Related by context. All words. (Click for frequent words.) 67 nucleolar 66 transferase 66 downregulation 66 mediated inhibition 66 costimulation 66 NADPH 66 oligomerization 65 tyrosine phosphorylation 65 membrane fusion 65 Cdc# 65 secretase 65 exocytosis 65 Vps# 65 beta subunit 65 transcriptional activation 65 degranulation 65 1alpha 65 guanosine 65 polyamine 65 adenylate cyclase 65 phosphatase 64 dependent protein kinase 64 anaphase promoting complex 64 MAP kinase 64 GTPase 64 replicase 64 recombinase 64 catenin 64 phosphatidylinositol 64 Phosphorylation 64 cytokine receptor 64 proteolysis 64 tropomyosin 64 oxidative phosphorylation 64 aminopeptidase 64 cytochrome c oxidase 64 phosphorylates 64 tetramer 63 osteoblast 63 demethylation 63 kinase domain 63 heterodimers 63 1beta 63 adipogenic 63 phosphoinositide 63 BMAL1 63 4E BP1 63 glycosyltransferase 63 deacetylation 63 β catenin 63 activin 63 ERK pathway 63 gluconeogenesis 63 N acetylglucosamine 63 prolyl 63 FasL 63 Rap1 63 acyl CoA 63 peptidase 63 coexpression 63 HIF 1a 63 S nitrosylation 63 proteolytic cleavage 63 constitutively active 63 dephosphorylation 63 adduct 63 glucokinase 63 BMP signaling 63 alpha subunit 63 kinase pathway 63 phosphorylate 63 mitotic progression 63 acetyl CoA 63 peroxisome 63 thymidine kinase 63 Cytochrome 63 methyltransferase 63 LPS induced 63 GAPDH 63 NF kappaB activation 63 JAK STAT 63 posttranslational modification 63 cyclase 63 Upregulation 63 Rac1 63 proto oncogene 62 oocyte maturation 62 diphosphate 62 dimerization 62 gene inactivation 62 reductase 62 cytoplasmic domain 62 cotransporter 62 Rab5 62 ERK1 2 62 lysophosphatidic acid 62 glycosylated 62 photosystem II 62 DNA demethylation 62 ubiquitination 62 S#K# 62 upregulates 62 operon 62 cyclooxygenase COX 62 isomerase 62 phosphoprotein 62 polypeptide 62 vesicle fusion 62 ribosomal protein 62 homodimers 62 Klf4 62 ß1 62 p# MAPK 62 cyclic nucleotide 62 pilus 62 Ca2 + 62 prostaglandin synthesis 62 cathepsin B 62 cytosolic 62 Peyer patches 62 intracellular proteins 62 hydroxylation 62 transcriptional regulation 62 Notch1 62 IRE1 62 PIP2 62 cytidine 62 astrocytic 61 transcriptional repressor 61 6S RNA 61 biosynthetic pathway 61 methyltransferases 61 conformational changes 61 substrate specificity 61 coactivators 61 1α 61 ENaC 61 Fas ligand 61 selenoproteins 61 MEK1 61 tumor suppressor protein 61 acyl 61 osteoblast differentiation 61 metabolic enzymes 61 isoenzyme 61 Vpr 61 adipogenesis 61 homolog 61 hydrolases 61 steroidogenesis 61 beta globin 61 histone H3 61 dimeric 61 transgenic mice expressing 61 inflammasome 61 Hedgehog signaling 61 IL #p# 61 deoxy 61 KLF4 61 receptor kinase 61 ATP hydrolysis 61 transactivation 61 cytochrome 61 SIRT2 61 mRNA splicing 61 mediated phosphorylation 61 STIM1 61 quinone 61 β1 61 intestinal mucosa 61 ERK phosphorylation 61 biogenesis 61 splice variants 61 serine protease 61 proteolytic 61 matrix metalloproteinases MMPs 61 transcriptional regulator 61 ribonucleoprotein 61 GABAA receptors 61 covalently attached 61 receptor mediated endocytosis 61 SGLT 61 Dpp 61 CTLs 61 heterochromatic 61 beta tubulin 61 SUMOylation 61 transduced 61 vesicle formation 61 Extracellular 61 cofactors 61 mRNA translation 61 IFN g 61 mediated apoptosis 61 CaM 61 secretory pathway 61 proteinase 61 polyadenylation 61 FOXO3a 61 eIF2 61 c MYC 61 caspase activation 60 peroxidase 60 glycosylation 60 transgene expression 60 FGFs 60 trimeric 60 coactivator 60 intracellular pH 60 calpain 60 pyrimidine 60 regulator CFTR protein 60 avidin 60 ACh 60 F actin 60 Protein Kinase C 60 morphogen 60 TrkA 60 secretory 60 peroxisomal 60 presynaptic 60 mitochondrial respiration 60 Nedd4 60 RAS RAF MEK 60 TNFR 60 downregulates 60 endocytic 60 thymocyte 60 prostaglandin E2 PGE2 60 MyD# 60 serpin 60 H#K# [001] 60 TGF b 60 beta. 60 ligand receptor 60 casein kinase 60 phagocytic cells 60 oxidase 60 Sgk1 60 cyclic AMP cAMP 60 Smoothened 60 protein tyrosine phosphatase 60 homodimer 60 Arp2 3 60 VE cadherin 60 PU.1 60 S6K 60 siderophore 60 muscarinic receptors 60 baroreceptor 60 CPEB 60 pertussis toxin 60 serine threonine 60 Tie2 60 amino terminal 60 lipoxygenase 60 mannose 60 GlcNAc 60 antiapoptotic 60 E3 ligase 60 condensin 60 matrix metalloproteinases 60 histone acetyltransferase 60 5' triphosphate 60 protein phosphatase 60 ubiquitin ligase 60 κ 60 transcriptional repression 60 TXNIP 60 colocalization 60 SOCS3 60 heterodimer 60 Hh pathway 60 IL 1β 60 PKC alpha 60 nodulation 60 AhR 60 uracil 60 ectopic expression 60 mitogen activated protein kinase 60 MyoD 60 hematopoietic progenitor cells 60 hydrolase 60 cell adhesion molecule 60 syntaxin 60 homeobox 60 tau phosphorylation 60 ATP synthase 60 chromosome condensation 60 pDC 60 bile acid 60 enzymatic reactions 60 actin binding 60 ras gene 60 telomeric 60 covalently linked 60 Flt3 60 E#F# 60 CRAC channel 60 T lymphocyte 60 fig. S6 60 inflammatory cytokine 60 cofactor 60 constitutively 60 PAX5 60 VEGF receptor 60 calcineurin 60 FGF signaling 60 overexpressing 60 caveolin 1 60 TFIIH 60 lyase 60 intracellular Ca 2 60 upregulate 60 Tubulin 60 urate oxidase 60 hypothalamic pituitary 60 histidine 60 mTORC1 60 depolarization 60 NF KB 60 RNA polymerases 60 electrophilic 60 receptor tyrosine kinase 60 ouabain 60 osteogenic 60 CD4 + T lymphocytes 60 Foxp3 60 phagocytosis 59 proximal tubule 59 kinase gene 59 Cdc7 59 amyloid formation 59 p# activation 59 palytoxin 59 triggers apoptosis 59 protein tyrosine kinase 59 ornithine 59 pyrophosphate 59 cell lysis 59 acinar 59 glyceraldehyde 3 59 N acetyl 59 cyclic peptide 59 polycystin 59 endonuclease 59 thymidylate synthase TS 59 hematopoietic progenitors 59 prostanoid 59 mineralocorticoid 59 IFN γ 59 tyrosine kinase receptor 59 transmembrane domain 59 modulatory 59 subcellular localization 59 dystroglycan 59 cyclin B1 59 CArG 59 SMN1 59 eIF4E 59 stably transfected 59 H#K#me# 59 phorbol 59 catalytically active 59 C1q 59 glucocorticoid receptor 59 cytokinesis 59 c myc 59 metalloprotease 59 PDGFR 59 enterocytes 59 NR2B subunit 59 Kir#.# 59 RNA polymerase II 59 adrenoceptor 59 upregulation 59 Wnts 59 anti apoptotic 59 triphosphate 59 LKB1 59 G6PD 59 Schematic representation 59 hypoxia inducible factor 59 β2 59 functionalization 59 dipeptide 59 vWF 59 GABAergic 59 glycolytic 59 hydroxylase 59 biosynthesis 59 peroxynitrite 59 glycogen metabolism 59 Dysregulation 59 solubilizing 59 NAD + 59 metalloproteinase 59 isoenzymes 59 tumorigenesis 59 gamete formation 59 sinoatrial node 59 p# mitogen activated 59 M1 muscarinic 59 carboxylase 59 bone morphogenetic proteins 59 ESCRT 59 potent inhibitors 59 SNARE complex 59 transcriptionally 59 TNFalpha 59 melanocyte 59 covalently bound 59 HDAC2 59 aminobutyric acid 59 Secretase 59 suppressor gene 59 cystic fibrosis transmembrane conductance 59 ncRNA 59 replicon 59 mitogenic 59 cellular prion protein 59 endocytosis 59 sequence homology 59 Drp1 59 TGF ß 59 nephron 59 palmitoylation 59 intramolecular 59 lysosomal 59 CagA 59 phosphorylase 59 vacuolar 59 tumor suppressor p# 59 potent stimulator 59 alpha secretase 59 catabolism 59 paracellular 59 fibril formation 59 Skp2 59 erythropoiesis 59 peptide receptor 59 beta globin gene 59 HepG2 cells 59 aldose reductase 59 chemisorption 59 IL6 59 virulence genes 59 c fos 59 endosomal 59 microsomal 59 heme oxygenase 59 paxillin 59 neurite outgrowth 59 p#Kip# 59 carboxyl terminal 59 anti CD3 59 pDCs 59 site directed mutagenesis 59 epoxide 59 glutamate receptor 59 synaptogenesis 59 gliadin 59 androgen receptor AR 59 palmitate 59 flavin 59 steroidogenic 59 cdk5 59 selectively inhibited 59 proapoptotic 59 JNK1 58 phosphatidylinositol 3 58 nitric oxide synthase NOS 58 PKC isoforms 58 oncogenic transformation 58 kD 58 neuronal signaling 58 keratinocyte 58 Western blotting 58 myofibroblast 58 lysates 58 receptor activation 58 kinetochore 58 tumorigenicity 58 receptor internalization 58 c MET 58 COL#A# 58 ubiquitylation 58 ERK signaling 58 cyclic adenosine monophosphate 58 diacylglycerol 58 TRAIL induced apoptosis 58 chaperone protein 58 ligases 58 Interferon gamma 58 cell adhesion molecules 58 nitration 58 inducible 58 DGAT1 58 STAT1 58 dsRNA 58 cytochrome c 58 endogenous ligand 58 Amino acid 58 furin 58 phospholipase 58 kinetochores 58 endonucleases 58 CEACAM1 58 dynamin 58 evolutionarily conserved 58 PGC 1α 58 nucleoprotein 58 phosphatases 58 adipocyte 58 proline rich 58 oligomeric 58 thrombospondin 58 PKM2 58 histone deacetylases HDACs 58 ATF2 58 CCL# 58 muscarinic 58 Fig. 2b 58 Cyclin E 58 antiproliferative activity 58 ^ sup ^ 58 cysteine protease 58 Sp1 58 apo AI 58 Annexin V 58 dynactin 58 hexose 58 LRP6 58 glycolipids 58 NHEJ 58 isotypes 58 EGF receptor 58 P2X 58 mitochondrial enzyme 58 adenosine diphosphate ADP 58 lytic 58 stoichiometry 58 antigenic epitopes 58 constitutively activated 58 chromosome segregation 58 nitric oxide synthase 58 Aromatase 58 nicotinamide 58 IRP1 58 Aâ 58 importin 58 fatty acid synthesis 58 HDACi 58 Hh 58 mucins 58 thyroid hormone receptor 58 transcriptional activity 58 cellular respiration 58 TGF β 58 hypothalamus pituitary 58 converting enzyme 58 tRNA synthetase 58 HEK# cells 58 TrkB 58 NF kappaB 58 histidine kinase 58 TRPV4 58 E3 ubiquitin ligase 58 aggrecan 58 γ 58 Histone 58 glucosides 58 neurofilament 58 TORC2 58 p# p# 58 histone methylation 58 c Myb 58 desaturase 58 C. albicans 58 plasminogen 58 microglial 58 mitochondrial biogenesis 58 MAPKs 58 c myb 58 PTH secretion 58 acyltransferase 58 LIS1 58 glucose transporter 58 Pax6 58 disulfide 58 phospholipase C 58 uPAR 58 acetylcholine receptor 58 autocrine 58 osteoinductive 58 Epithelial 58 subcellular compartments 58 annexin V 58 autophagic 58 P selectin 58 SCD1 58 plasmid encoding 58 primary cilium 58 haematopoietic 58 Eg5 58 CD1d 58 synaptic vesicle 58 S. enterica 58 mesoderm 58 Sertoli cell 58 Chinese Hamster Ovary 58 IKKß 58 Fig. 1c 58 BMP4 58 rRNA 58 lysis 58 RhoA 58 hematopoiesis 58 null mice 58 thymic 58 Monocyte 58 HIF 1alpha 58 mevalonate 58 microglial activation 58 JAK2 enzyme 58 bifunctional 58 druggable target 58 granzyme B 58 cytokine signaling 58 Cystic Fibrosis Transmembrane conductance 58 biotransformation 58 selectively binds 58 selective inhibition 58 neurotransmitter receptor 58 cyclin dependent kinase 58 monophosphate 58 Src kinase 58 ,#,# [002] 58 isoprenoid 58 M2 macrophages 58 Akt activation 58 Six3 58 axonal degeneration 58 C3 convertase 58 myofibroblasts 58 Matrix metalloproteinase 58 osteogenic differentiation 58 basolateral 58 depolarizing 58 induced phosphorylation 58 μ opioid receptor 58 RKIP 58 RAD# [001] 58 transmembrane domains 58 enzymatic pathways 58 postsynaptic 58 oxidases 58 potent inducer 58 ganglioside 58 actin polymerization 58 glycogen synthase 57 GLUT4 57 EGFP 57 phosphorylated proteins 57 downregulated 57 enzyme cytochrome 57 posttranslational modifications 57 esterase 57 Phenylalanine 57 BCL2 57 transferrin receptor 57 Topoisomerase II 57 KLF2 57 cytochrome P#s 57 eicosanoid 57 somatostatin 57 NFAT 57 malate 57 induced apoptosis 57 RUNX3 57 RNAi pathway 57 Oncogenic 57 PKC inhibitors 57 cell organelles 57 atherogenesis 57 Runx2 57 carboxy terminal 57 kDa protein 57 AMPA receptor 57 potentiator 57 degrading enzyme 57 WNK1 57 insulin secreting cells 57 histone deacetylases 57 methylated DNA 57 Clusterin 57 bFGF 57 isogenic 57 focal adhesions 57 FGFR3 57 centromeres 57 porphyrin 57 Notch receptor 57 Neuropeptide Y 57 thermosensitive 57 biotinylated 57 GLI1 57 enzyme inhibitor 57 apoptosis pathway 57 inhibitory effects 57 oncoprotein 57 PPARgamma 57 cysteine residues 57 erythrocyte 57 TNFa 57 neurotrophic 57 Rab# 57 Polymerase 57 outer membrane proteins 57 MT1 MMP 57 chemotactic 57 lysine residues 57 effector cells 57 IL 1beta 57 opioid peptides 57 urothelial 57 MEFs 57 antigen receptor 57 intestinal epithelial cells 57 fig. S1 57 gene rearrangements 57 Smad4 57 NS5A 57 membrane protein 57 sGC 57 bispecific 57 overactivation 57 tricalcium phosphate 57 cyclin dependent kinase inhibitor 57 post transcriptional 57 mRNA decay 57 budding yeast 57 transduction 57 anterior pituitary 57 tyrosine hydroxylase 57 leukemic cell 57 posttranslational 57 MAPK 57 amyloidogenic 57 deacetylase 57 neuromelanin 57 NFκB 57 β actin 57 leukocyte adhesion 57 apoptotic pathway 57 membrane proximal 57 TGF ß1 57 glutamate signaling 57 dehydrogenase 57 HIF 1α 57 NR2B 57 downregulate 57 DNMT1 57 enkephalins 57 Rho GTPases 57 NS4B 57 serine threonine kinase 57 transmembrane protein 57 excitation contraction 57 transmembrane 57 disulfide bond 57 ChR2 57 oxygenic photosynthesis 57 chloroplast 57 CD#b 57 histone H4 57 Microtubule 57 ribosome biogenesis 57 acetyltransferase 57 contractile 57 trans Golgi network 57 fig. S2 57 DNA methyltransferases 57 CXCL# 57 HCV replication 57 efflux 57 Notch signaling 57 noncoding RNA 57 fatty acyl 57 TH1 57 chondrocyte 57 KATP channels 57 Nampt 57 GTPases 57 procaspase 3 57 hepatoma 57 alanine 57 SREBP 57 cells transfected 57 connexin# 57 apoptotic 57 protein encoded 57 PIP3 57 hexamer 57 hydrolyze 57 HbF 57 activated macrophages 57 acrosome reaction 57 mu receptor 57 exonuclease 57 coiled coil 57 depolymerization 57 MTT assay 57 transcriptional regulators 57 ERa 57 tetramers 57 naturally occurring molecule 57 JCV 57 polymerize 57 γ secretase 57 endogenous 57 lymphangiogenesis 57 Eq. 57 regulated kinase ERK 57 hydroxypropyl 57 dihydrofolate reductase 57 constitutively expressed 57 B lymphocyte 57 defensin 57 homologous recombination 57 calcitonin gene related 57 hnRNP 57 homologues 57 COX2 57 myelination 57 activating mutation 57 amine oxidase 57 Akt signaling 57 polypeptides 57 microinjection 57 transmembrane receptor 57 adrenergic receptors 57 chloride channels 57 xanthine oxidase 57 synthesizing enzyme 57 iNOS 57 extracellular signal 57 Neutrophil 57 supernatants 57 Bcl 57 antimicrobial peptide 57 oligomer 57 tubulin 57 cysteines 57 cyclization 57 vascular endothelial cells 57 mRNA expression 57 intraventricular 57 receptor ligand 57 Fig. 2B 57 dedifferentiation 57 activate p# 57 Cyclin D1 57 Cre recombinase 57 Integrin 57 NKX#.# 57 cholesterol homeostasis 57 acetylated 57 plasma kallikrein 57 esterases 57 eNOS 57 endothelial nitric oxide synthase 57 LDL receptor 57 alveolar macrophages 57 pRb 57 cAMP signaling 57 Myosin II 57 complexation 57 lyse 57 synthases 57 BMP2 57 TIMP 57 HepG2 57 costimulatory molecules 57 Gln 57 c Src 56 synthetase 56 DMT1 56 metaphase 56 missense mutation 56 Cathepsin B 56 Inactivation 56 STAT3 signaling 56 synaptotagmin 56 tubulin polymerization 56 hTERT 56 IL 1ß 56 habenula 56 chemokine receptor 56 SGK1 56 inducible nitric oxide synthase 56 calcium homeostasis 56 spermatogenesis 56 N methyl 56 secrete proteins 56 transduce 56 scavenger receptor 56 Cajal bodies 56 amyloid β 56 PPARγ 56 pharmacological inhibition 56 synapse formation 56 proNGF 56 osteoclast formation 56 ciliated 56 sphingolipid 56 TGF β1 56 quantitative PCR qPCR 56 ciliary 56 Adrenergic 56 PHD2 56 LRP5 56 X inactivation 56 RNA binding 56 lysate 56 lactamases 56 proton pump 56 Superoxide 56 immunofluorescence microscopy 56 TSLP 56 meiotic recombination 56 neuronal migration 56 PTHrP 56 glucan 56 cathepsins 56 Catenin 56 ubiquitinated 56 Sox9 56 Signal transduction 56 dNTP 56 thrombin receptor 56 protein p# 56 Fig. 3B 56 immunostimulatory 56 nucleolin 56 cAMP dependent 56 phosphatidylcholine 56 di GMP 56 anergy 56 proteolytic activity 56 oxidative enzymes 56 glutamyl 56 adhesion molecule 56 chemically modify 56 osteoclast activity 56 fatty acid synthase 56 chemotaxis 56 PI3K/Akt 56 ErbB receptors 56 cystic fibrosis transmembrane 56 IGFBP2 56 ERalpha 56 regulates gene expression 56 biomolecule 56 HSF1 56 Fig. 1A 56 Htt 56 L alanine 56 nucleic acid molecules 56 lysing 56 CDKs 56 lipogenesis 56 XBP1 56 methylate 56 cytoskeletal protein 56 acetylcholinesterase AChE 56 mRNA encoding 56 cytokine receptors 56 physiologically relevant 56 arabinose 56 Vascular endothelial growth 56 mononuclear 56 proinflammatory 56 integrin activation 56 PI3K Akt 56 TIR1 56 SOX9 56 protein acetylation 56 Î ² 56 guanine nucleotide exchange 56 diffusible 56 IGF1R 56 small molecule activators 56 immunodominant 56 ERK2 56 intracellular signaling 56 redox reactions 56 induced cytotoxicity 56 kinesin motor