Related by context. Frequent words. (Click for all words.) 70 mitochondrial dysfunction 66 cardiac hypertrophy 66 NF1 64 myelination 64 metabolic abnormalities 64 Notch signaling 64 GPR# [002] 64 malignant transformation 64 NKT cells 64 genomic instability 63 neuroendocrine 63 genetic alterations 63 Angelman syndrome 63 dysregulated 63 Wnt signaling 63 autosomal dominant 63 myotonic dystrophy 62 mice lacking 62 tumor suppressor gene 62 DISC1 62 molecular pathway 62 Oxidative stress 62 telomere shortening 62 leptin resistance 62 presenilin 62 misfolding 62 pathophysiological 62 progressive degeneration 61 genetic defect 61 mutant protein 61 genetic abnormality 61 protein misfolding 61 immunodeficiency 61 STAT3 61 MDM2 61 tau protein 61 muscular dystrophies 61 LRRK2 60 genetically inherited 60 nonsense mutation 60 proteolysis 60 mutations 60 Wnt pathway 60 cellular pathways 60 molecular pathways 60 glutamate receptors 60 EZH2 60 demyelination 60 Mitochondrial 60 Neuronal 60 SORL1 60 mammary tumors 60 poorer prognosis 60 neurodegenerative disorder 60 hyperinsulinemia 60 APOE4 60 dysregulation 60 molecular mechanisms underlying 59 tumorigenesis 59 retinal degeneration 59 neuropsychiatric disorders 59 familial hypercholesterolemia 59 Insulin resistance 59 NAFLD 59 IGF1 59 autoimmunity 59 genetic alteration 59 gene mutations 59 Retinopathy 59 signaling pathway 59 acute myelogenous leukemia AML 59 downregulation 59 gene mutation 59 mutated genes 59 disc degeneration 59 TGF beta 59 Fanconi anemia 59 p# gene 59 SIRT1 59 neurodevelopmental disorders 59 mutation 59 overactivity 59 motor neuron 59 protein kinase C 59 genetic mutation 59 medulloblastoma 59 ApoE 59 progeria 59 CMV infection 59 spermatogenesis 59 nonsense mutations 58 phagocytosis 58 astrocyte 58 neurodegenerative disease 58 aneuploidy 58 RANKL 58 amyloid deposits 58 JAK2 58 oncogenic 58 Th# cells 58 beta catenin