Related by context. All words. (Click for frequent words.) 75 temperature modulation 66 InnerCool endovascular 66 RapidBlue TM 62 RhinoChill 62 Neovasc Reducer 61 CoolBlue TM 61 Catheter System 60 CryoCor Cardiac Cryoablation System 60 LEUKINE 60 Ventavis 60 MicroThermX 60 SmoothShapes XV 60 Abbokinase 59 treat cardiac arrhythmias 59 NAVISTAR R 59 RhinoChill System 59 Aloxi R 59 CAPHOSOL R 59 EAA TM 59 EpiCeram 58 Zipsor 58 CardioFit 58 INOmax 58 Cotavance 58 refractory angina 58 vapreotide acetate 58 Cellegesic 57 Levulan PDT 57 FORE SIGHT 57 ExAblate R 57 Eluting Coronary Stent System 57 Azedra 57 ColonRing 57 ThermoSuit System 57 orthoPACE 57 Loramyc R 57 Paradigm Spine 57 Myocet 57 Fibrin Pad 57 Zirgan 57 OMNARIS HFA 57 Européenne Mark 57 ActiPatch Therapy 57 oxybutynin gel 56 skin permeation 56 vivo glucose 56 CRMD# 56 Vasomedical enhanced 56 drug eluting coronary stent 56 FloTrac 56 AneuRx AAAdvantage 56 hypervascular tumors 56 mechanical thrombectomy 56 Saizen R 56 IMRIScardio 56 RX ACCULINK 56 AzaSite Xtra 56 Contura MLB 56 Hydrelle 56 OmniWave 56 sumatriptan DosePro 56 SurgiFrost 56 VenaCure 56 BioSTAR R 56 Surgical Sealant 56 photodynamic therapy PDT 56 Myotech CSS 56 SonicOne 56 Cardica Microcutter XPRESS 56 Masimo Rainbow SET Pulse 56 carboxyhemoglobin SpCO 56 Zingo TM 56 AGGRASTAT ® 56 rocuronium bromide 56 Uracyst ® 56 SEDLine 56 DUROS 56 ThromCat 56 BioSTAR ® 55 EVICEL 55 HydroFix 55 catheter occlusion 55 urethral bulking agent 55 Precedex 55 OsseoFix 55 Microwave Ablation System 55 OMNARIS Nasal Spray 55 GED aPC 55 CAPHOSOL 55 AngioJet R 55 bifurcation stent 55 RE COVER 55 NEXTERONE 55 Levulan R 55 drug eluting stent DES 55 Ascendra 55 VALSTAR 55 Hemolung 55 Cooled ThermoTherapy 55 patented Bioral 55 Mobi C 55 TREDAPTIVE 55 treat refractory angina 55 BrachySil TM 55 Pharos Vitesse 55 Thermogard XP 55 Smartlipo MPX 55 Microstream 55 Sanvar R 55 PROMUS Element 55 REVELATION ® 55 Focused Ultrasound 55 TriReme 55 Litx 55 MEDRAD INC. 55 SANVAR 55 MYDICAR ® 55 Tavocept 55 nSpire Health 55 TAXUS Element Paclitaxel Eluting 55 Powerlink ® 55 Transdel TM 55 Alair System 55 Neurobionix 55 ablation catheters 55 IMRISNV 55 AZILECT ® 55 PATHFINDER R 55 peripheral stent 55 Plexur P 55 Cryoablation System 54 Left Ventricular Assist 54 Captisol 54 photodisinfection 54 Cell Pouch System 54 external counterpulsation systems 54 RECOTHROM R 54 radiofrequency RF energy 54 INTEGRILIN 54 Paradis Vaso Shield 54 PrandiMet 54 thrombus removal 54 topical NSAID 54 Metricath Gemini 54 Campath ® 54 ThermoDox ® 54 Cand5 54 Revo MRI 54 PATHFINDER ® 54 Optical Biopsy System 54 RenalGuard Therapy 54 Biliary System 54 OncoGel 54 RapidBlue 54 Ablation Frontiers 54 INOMAX 54 AxiaLIF 54 Nuclear Pharm Assist 54 SonoPrep 54 cryosurgical treatment 54 CentriMag 54 JenaValve 54 acetonide FA 54 Cellulaze 54 orthoPACE ™ 54 INTELLITEMP ® 54 StomaphyX 54 CO Oximetry 54 TriActiv 54 MYO VAD 54 EOquin TM 54 Neovasc Reducer TM 54 Personalized Immunotherapy 54 Miracor 54 systemic immunosuppressive drugs 54 KL4 surfactant 54 Surgical Ablation System 54 Calmare Therapy Treatment 54 AngioSculpt Scoring Balloon Catheter 54 herpetic keratitis 54 ALVESCO HFA 54 Avedro 54 QuadraSphere 54 FlexStent ® 54 LC Bead 54 Ventavis ® 54 QVAR 54 peripheral vascular stent 54 REVELATION ® Series 54 Adhesion Barrier 54 external counterpulsation 54 liposomal formulation 54 percutaneous aortic valve 54 drug eluting balloons 54 EverFlex 54 Icatibant 54 NeuroStar TMS Therapy 54 Dynamic Spine Stabilization 54 liquid fibrin sealant 54 brand ciclesonide HFA 54 CompuFlo 54 Evicel 54 Visonac TM 54 WavSTAT 54 VBLOC TM 54 intravascular 54 ClosureFAST 54 SANUWAVE 54 Ketotransdel 54 Zelrix 54 PROMUS 54 anti emetic therapy 54 Hemopurifier ® 54 Excellagen 54 Tarmogen 54 Besivance 54 PLX cells 53 IONSYS TM 53 noninvasive diagnostic 53 Pervasis 53 Vasomedical 53 CCR9 antagonist 53 TriActiv R 53 ALVESCO ® 53 bioabsorbable polymer 53 EECP R 53 CytoSorb TM 53 DepoBupivacaine TM 53 PerClot 53 REVELATION R 53 EndoFLIP 53 Emboshield 53 Arikace 53 MiniArc Precise 53 Sublative Rejuvenation 53 sublingual formulation 53 Hemospan 53 TMS Therapy 53 reslizumab 53 Stabilimax 53 Embolic Protection System 53 RenalGuard System TM 53 IntuiTrak 53 Vasogen Celacade 53 TactiCath 53 ABLAVAR ® 53 CRH O'Regan System 53 surgical ablation 53 Topical Suspension 53 Electronic Brachytherapy 53 PEAK PlasmaBlade 53 photodynamic 53 Novacor R 53 NeoVisc ® 53 AutoloGel System 53 PATHFINDER ® TRACER 53 TURBO Booster 53 irrigated catheter 53 ESBA# 53 Sonolith i move 53 Cerebral Oximeter 53 Surgical Mesh 53 ablation catheter 53 Custom NX 53 therapy PBRT 53 Endovascular System 53 Stabilimax NZ 53 ClosureFAST catheter 53 Ozurdex 53 eMatrix 53 compound Homspera 53 Perforomist ™ Inhalation Solution 53 RLY# 53 InterStim Therapy 53 Dural Sealant 53 IFS 2C 53 nasal antihistamine 53 Amplimexon 53 Oridion 53 CytoSorb 53 Anti Bacterial Envelope 53 AngioJet 53 liposomal doxorubicin 53 iChemVELOCITY 53 SUPERA VERITAS 53 ZoMaxx 53 MedicalCV 53 Humate P 53 CoreValve System 53 CD HORIZON 53 Direct Visualization 53 MGuard TM 53 Tekamlo 53 liver resection surgeries 53 TAXUS Liberté stent 53 ABThera 53 Stedivaze 53 Freezor 53 Thrombectomy System 53 MyoCell 53 inhaled prostacyclin 53 visit www.dobimedical.com 53 SoloPath 53 Monovisc 53 ARIKACE 53 Vivaglobin 52 Cardiolite 52 Anturol TM 52 EndoTAG TM 52 TARIS 52 Xcelerant Delivery System 52 TandemHeart System 52 coronary stent merged 52 bioabsorbable stent 52 resorbable biomaterials 52 ulimorelin 52 Cardio Vascu Grow 52 lucinactant 52 NeuroFlo 52 Liprostin 52 Valiant Thoracic Stent Graft 52 FullTerm 52 Lexiscan 52 somatostatin analogues 52 transmucosal delivery 52 R Perfexion TM 52 GTC recombinant human 52 INFUSE R 52 Embrella Embolic Deflector 52 NexACT ® 52 Uracyst R 52 inhaled formulation 52 AEG# 52 Endotis 52 Voltaren Gel 52 Bioral Amphotericin B. 52 Rainbow SET 52 Ceragenin ™ technology 52 transcatheter 52 OrSense 52 Cleviprex TM clevidipine 52 Sirolimus eluting Coronary Stent 52 STARFlex R 52 Dual Opioid 52 Lymphoseek ® 52 SNALP technology 52 punctal plug delivery 52 XOPENEX 52 Attrius 52 AngioJet System 52 Isolagen Process 52 PD2i Analyzer 52 Atom Stent 52 omega interferon 52 Tissue Matrix 52 biliary stent 52 XIENCE 52 kidney urologic 52 tissue ablation 52 Ketotransdel TM 52 NeuroMove 52 CytoSorb ™ 52 magnetic irrigated catheter 52 thrombolytic agents 52 HeartNet 52 Cyanokit R 52 drug eluting balloon 52 Facet Solutions 52 PRIALT 52 BioCision 52 FORE SIGHT r 52 Revimmune 52 OsteoGram 52 Polyzene R F 52 LipiScan IVUS 52 ThermoDox R 52 microcatheter 52 Therapeutic hypothermia 52 Turbo Tandem 52 TUMT 52 Lauriad 52 DepoDur TM 52 MelaFind R 52 Spinal Elements 52 OZURDEX 52 Catena ® 52 BFPET 52 treat atrial flutter 52 Resten NG 52 biologic therapeutics 52 Coronary Stent System 52 TheraSphere R 52 clevidipine 52 transcatheter aortic valve 52 interventional therapies 52 REPEL CV 52 AngioScore 52 IVTM 52 WATCHMAN device 52 MGuard ™ 52 Iluvien ® 52 Hizentra 52 noninfectious uveitis 52 Xencor XmAb 52 Nellix 52 QTinno TM 52 Axxent R 52 LibiGel ® 52 plasma kallikrein inhibitor 52 iobenguane 52 Actemra tocilizumab 52 ALTROPANE 52 CTO recanalization 52 AngioSculpt 52 StromaCel 52 aortic stent grafts 52 Degarelix 52 TAXUS Liberte 52 ablation procedures 52 INTELLITAB TM 52 COMT inhibitors 52 Unite Biomatrix 52 Oxiplex 52 replacement PAVR 51 DermTech International 51 laser assisted lipolysis 51 Endologix Powerlink System 51 Powerlink System 51 biodegradable implant 51 Flutiform TM 51 HyACT 51 REG1 51 INVOS System 51 paclitaxel eluting 51 SPRIX ® 51 vernakalant hydrochloride 51 Diamondback #deg 51 Angiox 51 PosiRx 51 Photomology 51 Vascular Wrap TM 51 Coherex FlatStent 51 BioScanIR R System 51 LightTouch 51 clot retrieval 51 AzaSite TM 51 fully bioabsorbable 51 eSVS MESH 51 surgical sealant 51 EndoFLIP ® 51 Nektar PEGylation technology 51 Symadex 51 Self Expanding Stent 51 OxiMax 51 nCPAP 51 tezampanel 51 XIENCE V stent 51 High Intensity Focused 51 DACH platinum 51 Biopsy System 51 tolperisone 51 convenient dosing regimens 51 SagaX 51 FORE SIGHT Absolute Cerebral 51 REOPRO 51 Edwards SAPIEN valve 51 OSMOPREP 51 BXT # 51 OsteoSponge ® SC 51 TachoSil 51 vertebral augmentation 51 Cysview 51 ThermoDox 51 CVProfilor 51 Trevo System 51 miniaturized implantable 51 Transurethral 51 VertiFlex ® 51 Biomerk Tumorgrafts 51 automated radiopharmaceutical distribution 51 Intravail ® 51 VBLOC Therapy 51 Bone Graft 51 BUPIVACAINE SURGICAL IMPLANT 51 mertansine 51 Cryoablation 51 SIR Spheres 51 +# degreesC 51 Optical Coherence Tomography OCT 51 Traficet EN 51 PresbyLens ® 51 ELACYT 51 accommodating IOL 51 Sygnis 51 Nellcor OxiMax 51 disposable catheter 51 DEEP AF 51 Combo Stent 51 DFine 51 HDL Selective Delipidation 51 Hiden Analytical 51 Aztreonam 51 ProSavin 51 EP# [005] 51 Embosphere Microspheres 51 Pivotal Trial 51 amikacin 51 Microplasmin 51 PFO closure 51 Telatinib 51 HALO# [002] 51 powderREV R 51 Cerashield 51 prostatic tissue 51 Endurant stent graft 51 GIPET 51 Adnectin 51 Gel Delivery Technology 51 Eraxis 51 luliconazole 51 liposome formulation 51 Ablatherm 51 silicon nitride ceramic 51 Epoprostenol 51 Embolic Protection Device 51 Rheos System 51 BCG refractory carcinoma 51 cerebral oximetry 51 ThromCat TM 51 Yondelis ® 51 Tryton Side Branch 51 CATANIA TM Coronary Stent 51 Cook Zenith TX2 51 alfa interferon 51 millisecond annealing 51 XIENCE PRIME 51 Omigard 51 Vascugel 51 Oximetry 51 PROMUS TM 51 stent coating 51 novel oral anticoagulant 51 ClearPath HDR 51 Thermage CPT 51 Coronary Stent 51 Benign Prostatic Hyperplasia BPH 51 Captisol Enabled 51 Lung Flute ® 51 ClearPath TM 51 intravascular imaging 51 CompuDent 51 Vascular Closure Device 51 Nanobody ® 51 vidofludimus 50 VAPRISOL 50 GreenLight XPS 50 Toraymyxin 50 MyoCath 50 Naviscan 50 HuMax Wnt 50 Fetal Fibronectin Test 50 Methylnaltrexone 50 XP #L 50 Bionate ® PCU 50 Plasmin 50 Chemetics R 50 Integrilin 50 radiofrequency RF 50 FlowCardia Inc. 50 IMPELLA 50 Stereotaxis System 50 HuMax EGFr 50 Biotec Pharmacon 50 DXL TM 50 endoluminal stent graft 50 multimodality imaging 50 electrosurgical generator 50 percutaneous catheter 50 Expression PACE 50 MYOBLOC 50 delivers fluocinolone acetonide FA 50 antithrombotics 50 VERSANT 50 immunodiagnostic 50 paclitaxel eluting stent 50 GORE TAG 50 Hexvix 50 Celution TM System 50 oral taxane 50 RAPAFLO 50 ATS CryoMaze 50 CorPath 50 generation rotary VAD 50 cinacalcet 50 Polymer Microspheres 50 Spirus Medical 50 NeuroAid TM 50 Octreotide 50 ™ Everolimus Eluting 50 PRT# 50 MAGE A3 ASCI 50 Xyfid 50 Neuromodulation System 50 Cardio3KG 50 CryoSeal FS System 50 pulsed electromagnetic field 50 VIAdel TM technology 50 MiniArc 50 VerifyNow System 50 vivo fluorescence imaging 50 MGN# 50 iChem R 50 BioSilicon 50 ATS CryoMaze TM 50 AcceleDent 50 StarClose 50 HVAD 50 Artelon ® 50 eTag assays 50 candidate NGX 50 BEMA TM Fentanyl 50 EP #R 50 osteobiologic 50 eBx 50 INTRABEAM 50 KALBITOR 50 hereditary deficiency 50 Powerlink XL 50 interferon beta therapy 50 XIENCE V Everolimus Eluting 50 investigational therapies 50 Covered Stent 50 SpaCapsule ® 50 maximally tolerated 50 CLENZIderm MD 50 Mitralign 50 Endoprosthesis 50 Merci Retrieval System 50 intranasal delivery 50 embolic protection device 50 TissuGlu 50 Cinnergen TM 50 ATS 3f Aortic Bioprosthesis 50 PEGylation technology 50 Panzem 50 Toraymyxin TM 50 TELIGEN 50 CSZ Medical 50 vertebral compression fractures 50 platinum chromium alloy 50 Reconstructive Tissue Matrix 50 opioid analgesia 50 Amelior 50 CINQUIL 50 BeneChill 50 Transdrug ® nanoparticle 50 HIFU therapy 50 Drug Eluting Stent System 50 Diamondback Predator 50 intravascular stent 50 PressureWire Certus 50 PROMUS Element Stent 50 HepaSphere 50 TM Embolic Protection 50 MammoView 50 Crystalens AO 50 ViaDerm 50 THERMOCOOL R 50 GlucoLight 50 efficacy tolerability 50 cardiac ablation procedures 50 Vascular Imaging 50 cardiac resynchronisation therapy 50 BioMatrix 49 drug zotarolimus 49 Aggrastat ® tirofiban hydrochloride 49 CE Marked 49 GORE VIABAHN Endoprosthesis 49 ReValving 49 lapatinib Tykerb 49 synthetic retinoid 49 HepaLife TM 49 anti infective therapies 49 thermal ablation 49 pain palliation 49 Zysolin TM 49 RADIESSE 49 Eurocor 49 MGuard stent 49 MEK inhibitor RDEA# 49 ApoB SNALP 49 Levacor 49 nonfusion 49 CoFactor 49 Plenaxis TM 49 ® Perfexion 49 Macroplastique ® 49 NumaDerm 49 buccal delivery 49 PROMACTA 49 MoxDuo 49 PROSTASCINT R 49 Aquapheresis 49 peripheral arterial 49 GelSite R polymer 49 MagniFuse 49 MicroPulse 49 laparoscopic instruments 49 stent DES 49 MediServe 49 Somatuline ® 49 NATRECOR ® 49 Microstream R capnography 49 hylan GF 49 Civacir 49 Heartmate 49 Masimo Rainbow SET 49 oral anticoagulant 49 Company proprietary Biochronomer 49 endovascular stent graft 49 granisetron 49 Metricath 49 Myoview 49 GORE TAG Device 49 immunocompromised patients 49 Epi LASIK 49 cardiac contractility 49 CorMatrix ECM 49 Vascular Grafts 49 Elekta Infinity 49 Talent Abdominal 49 VerifyNow 49 ablative therapy 49 antiarrhythmic drug 49 TM Drug Eluting 49 Omalizumab 49 Angio Seal 49 sodium chondroitin sulfate 49 Elagolix 49 surgical microscopes 49 Mitoxantrone 49 oncolytic virus 49 NanoWizard ® 49 bioartificial liver 49 Clearant Process R 49 embolics 49 microcirculatory 49 my3KG 49 PressureWire 49 Nitrolingual 49 Plexur M 49 Magnetecs 49 Contramid 49 vitamin D analogs 49 TAXUS Stent 49 Waterlase MD 49 Medtronic CoreValve System 49 vascular interventional 49 C7 XR 49 pharmacologic agents 49 treprostinil 49 L L Glutamine 49 Biolimus A9 49 SERMs 49 MetroGel R 49 Symplicity Catheter System 49 SPARC Enterprise servers 49 antiangiogenic agents 49 ComfortScan 49 EnCor 49 INT# [002] 49 AFRS TM 49 PreDx DRS 49 ACEON R 49 INTRABEAM ® 49 electrophysiology EP 49 Trofex 49 CryoMaze 49 Inhaled nitric oxide 49 Bryan Cervical Disc 49 ERYtech Pharma 49 GORE EXCLUDER AAA Endoprosthesis 49 DUSA Levulan 49 Acuson S# 49 Provent Therapy 49 immune modulatory 49 Plicator 49 SpideRX 49 ablation therapy 49 intracavitary 49 Delcath PHP System 49 PlasmaBlade 49 Rezular 49 therapeutic regimens 49 Dicer Substrate Technology 49 ruxolitinib 49 Applied Biosystems TaqMan 49 Endoscopic Ablation System 49 Vacuum Assisted Closure 49 OnControl 49 minimally invasive spinal fusion 49 TM Everolimus Eluting 48 Terumo CVS 48 Protelos 48 Interventional Spine 48 Zone Sonography TM 48 Stent Graft 48 sublingual route 48 TrueBeam 48 catheter ablation procedures 48 fluidjet 48 oral anticoagulants 48 Cardica Microcutter 48 PressureWire R 48 Fully Covered Stent 48 anticoagulant reversing agent 48 Warfarin Sensitivity Test 48 Crit Line 48 ReValving System 48 Oral Mucositis 48 Microvolt T Wave Alternans 48 hemostatic bandage 48 Peptidomics 48 VESTAsync 48 FIRMAGON R 48 Lymphoseek 48 RapidBlue System 48 transapical 48 ENLIGHT 48 counterpulsation 48 MacuSight 48 Capsulution 48 Ossatron R 48 SCNP 48 WS CRDS 48 antifungal therapy 48 endoluminal 48 PICC WAND 48 EndoTool 48 interventional oncology 48 Abbott HUMIRA 48 Augment Injectable 48 PD2i ® nonlinear algorithm 48 ABSORB trial 48 IN.PACT 48 HIF PH inhibitors 48 Axial Biotech 48 Optical Coherence Tomography 48 EndoBarrier 48 Bendavia 48 Leksell Gamma Knife Perfexion 48 Ophena 48 Balloon Sinuplasty TM 48 Technosphere ® 48 NIOX 48 VIVIMIND TM 48 toric lens 48 BriteLight 48 thermometry 48 Smartlipo Triplex 48 TLIF 48 DsiRNA 48 HALO# [001] 48 inhaled AAT 48 Permacol 48 MoxDuo IR 48 antiarrhythmic agent 48 cardiac PET 48 Sofradir EC 48 gamma detection 48 rEV# 48 Bucindolol 48 small molecule PEGylation 48 GORE VIABAHN ® 48 Visian Toric ICL 48 gynecologic procedures 48 myocardial infarct size 48 Combidex 48 Microcyn Technology platform 48 AVONEX PEN 48 CCX# 48 EchoCRT 48 ADAGIO study 48 QTinno 48 pharmacological chaperone 48 therapeutic radiopharmaceuticals 48 PolyTouch 48 CYPHER SELECT TM 48 Thrombectomy 48 GEM OS1 48 linear ablation 48 TECNIS ® 48 Lumbar Interbody Fusion 48 First Patient Treated 48 Ophena TM 48 OnDose TM 48 Xclair 48 XmAb# 48 iliac artery disease 48 PER.C6 ® production 48 Fondaparinux 48 Corus CAD 48 fentanyl citrate 48 PD2i algorithm 48 Tesetaxel 48 PD2i 48 NAVISTAR ® THERMOCOOL ® 48 -# degreesC 48 DEFINITY ® 48 Cardima Surgical Ablation System 48 TAXUS Liberte Stent 48 unoprostone isopropyl 48 uricase 48 preclinically 48 Coagulation System 48 Octreolin 48 Photodynamic therapy PDT 48 Purion ® 48 Revascor TM 48 miRview mets 48 retinal disorders 48 BeneFIX 48 Talent Abdominal Stent Graft 48 Apoptone 48 PROPRIO FOOT 48 OMS#HP 48 Genous 48 fosbretabulin 48 Axiogenesis 48 Activity Assay 48 EVLT 48 refractory recurrent 48 ABSORB 48 Linkam 48 radiofrequency ablation 48 CORTOSS 48 VeraTag 48 LAM IPM TM 48 electrocardiography ECG 48 TOCOSOL 48 Juvederm Ultra 48 Aerocrine 48 CO2 lasers 48 Micropelt 48 PureGraft ™ 48 bioartificial liver device 48 Multiferon R 48 Interferon alpha 48 Laser Lok 48 platelet inhibitor 48 iFuse Implant System 48 therapeutic modalities 48 Mitral Contour System 48 sulodexide 48 xCELLigence 48 LipiScan 48 Acute Ischemic Stroke 48 amifostine 47 CBLC# 47 SuperStitch 47 antifungal agent 47 Novacor LVAS 47 #F ML 47 Sugammadex 47 Embozene TM Microspheres 47 MelaFind ® 47 Labguard ™ 47 NEVO TM 47 ASTIGMATISM 47 TheCompany 47 hydrophilic coating 47 Platinum Chromium 47 WatchPAT 47 Heparin Bioactive Surface 47 rhITF 47 Thoracic Endoprosthesis 47 anti thrombotic 47 PSMA ADC 47 multiplexed assays 47 Acthar Gel 47 Radiofrequency ablation 47 SNALP 47 RSD# 47 transurethral 47 cardiac perfusion 47 small molecule activators 47 Diabetic Macular Edema 47 rxRNA ™ compounds 47 MIST II 47 Nitinol Stent 47 nonlinear algorithm 47 received CE Conformité 47 Fractional Flow Reserve 47 dermaPACE 47 laser photocoagulation 47 NPWT 47 extracorporeal 47 proprietary Zone Sonography 47 renin inhibition