Related by context. All words. (Click for frequent words.) 60 posttest 58 SGRQ 58 NIH CPSI 58 YMRS 58 UPDRS motor 58 Rating Scale MADRS 58 Montgomery Åsberg Depression 57 nasal symptom 57 DLQI 57 HAMD 56 Brief Psychiatric 56 IBDQ 56 Stroke Scale NIHSS 56 CNS LS 56 BMI z 55 PSQI 55 HDRS 55 QIDS SR 55 depressive symptom 55 PHQ 9 55 PANSS 55 ADAS cog 55 CDAI 55 PERMP 55 Crohn Disease Activity 55 Neuropsychiatric Inventory 55 NYHA functional class 55 MADRS score 55 p = .# [001] 55 GERD symptom 54 Global Impression CGI 54 PANSS total 54 FACIT Fatigue 54 Severity Index PASI 54 dose Iluvien 54 ADCS CGIC 54 Montgomery Asberg Depression 54 Stroke Scale 54 interrater reliability 54 HbA 1c levels 53 CHADS2 53 subscore 53 APACHE II 53 hemoglobin A1c levels 53 Alzheimer Disease Assessment 53 EQ 5D 53 Index CDAI 53 HbA 1c 53 NIHSS score 53 HAQ DI 53 calculated creatinine clearance 53 IPSS 53 NIHSS 53 subscales 53 Status Scale EDSS 53 HbA1c levels 53 CPAP adherence 53 glycated hemoglobin levels 53 MMSE score 52 Depression Inventory 52 posttreatment 52 meta regression 52 postintervention 52 HRQL 52 Y BOCS 52 biopsy Gleason 52 Renal Cell Carcinoma RCC 52 ICD therapy 52 Pain Intensity 52 ADAS Cog 52 ADHD RS 52 Visual Analog 52 adenotonsillectomy 52 FDG PET scan 51 Scale PANSS 51 UPDRS 51 subscores 51 HbA1C 51 CDAI score 51 Primary endpoints 51 Score DAS# 51 subscale scores 51 HRQoL 51 glycated hemoglobin HbA1c 51 TNSS 51 QoL 51 erection hardness 51 Secondary efficacy endpoints 51 interobserver reliability 51 hemodialysis patients 51 HAM D# 51 neuropsychological assessment 51 Reynolds Risk Score 51 exploratory endpoints 51 CORE OM 51 oral anticoagulation 51 multivariable analysis 51 somatization disorder 51 Ishak fibrosis score 51 HRQOL 50 #q# deletion syndrome 50 Subgroup analysis 50 Secondary endpoints include 50 psychoeducational 50 DAS# [002] 50 retrospective cohort 50 subjective sleepiness 50 receiving VICTRELIS 50 MADRS 50 salivary cortisol 50 exhaled nitric oxide 50 Hb A1C 50 postoperative complication 50 cirrhotic patients 50 dose atorvastatin 50 HOMA IR 50 DQI 50 QRS duration 50 Neuropsychiatric Inventory NPI 50 Charlson Comorbidity Index 50 COR Analyzer 50 HF ACTION 50 Negative Syndrome 50 glycosylated hemoglobin levels 50 MS DRG 50 Cardiorespiratory fitness 50 antidiabetic medication 50 nondiabetic patients 50 Health Assessment Questionnaire 50 Fibromyalgia Impact Questionnaire 50 Glasgow Coma Scale 50 MMSE scores 50 recurrent venous thromboembolism 50 PASI scores 50 procalcitonin 50 PSA nadir 50 preintervention 50 sociodemographic factors 50 Charlson comorbidity index 50 hydroxyvitamin D levels 49 platelet reactivity 49 metabolic parameters 49 bariatric surgical 49 Likert scale 49 autonomic dysfunction 49 Methods Retrospective 49 EDEMA3 trial 49 postoperative mortality 49 WOMAC pain 49 elective PCI 49 p = #.# [003] 49 VFQ 49 prognostic variables 49 diabetes mellitus DM 49 liver histology 49 biochemical recurrence 49 Sociodemographic 49 ETDRS 49 pharmacologic stress 49 atherogenic dyslipidemia 49 psychiatric outpatients 49 metaanalysis 49 Clinician Administered PTSD 49 intraobserver 49 rt PA 49 Geriatric Depression 49 timepoint 49 oral anticoagulant therapy 49 PROTECT II 49 baseline HbA1c 49 Cronbach alpha 49 F FDG PET 49 Interrater reliability 49 CHADS 49 multivariate regression analysis 49 CI -#.# 49 CRp 49 clinical pharmacology studies 49 electrophysiologic 49 meta analytic 48 serum sodium levels 48 intravenous tPA 48 OSDI 48 virological response 48 Unified Parkinson Disease 48 EORTC QLQ C# 48 MMSE 48 psychosocial functioning 48 hip BMD 48 MetS 48 posttransplant 48 psychiatric comorbidity 48 baseline PASI 48 CR nPR 48 glycated hemoglobin 48 nonpharmacologic 48 serum creatinine levels 48 CHAMPION PCI 48 leukocyte count 48 Hamilton Rating Scale 48 serum lipid levels 48 semiquantitative 48 RYGB 48 preoperative PSA 48 IIEF 48 dose escalation phase 48 comorbidity 48 subtests 48 Epworth Sleepiness Scale 48 somatic symptom 48 Multivariate logistic regression 48 STN stimulation 48 adenoma recurrence 48 convergent validity 48 Skin sterol 48 eculizumab therapy 48 Pain Rating Scale 48 International Prostate Symptom 48 postdischarge 48 multivariate analyzes 48 macroalbuminuria 48 Meta analyzes 48 aldosterone antagonist 47 RTOG 47 CINQUIL 47 retrospective observational study 47 postoperative radiotherapy 47 sonographic examinations 47 virologic response 47 multivariate logistic regression 47 D dimer 47 tumor histology 47 Scale EDSS 47 Negative Symptoms 47 underwent liver transplantation 47 mTSS 47 prospectively defined 47 polysomnographic 47 HSCT 47 Rating Scale UPDRS 47 liver biopsies 47 ICD implants 47 hematologic parameters 47 MELD 47 State Exam MMSE 47 randomized controlled trials RCTs 47 sustained virologic response 47 femoral neck BMD 47 inhaled AAT 47 RE LY 47 undetectable HBV DNA 47 binary logistic regression 47 State Examination MMSE 47 PROLARIS 47 antioxidant supplementation 47 NSQIP 47 MSCT 47 EDSS score 47 symptomatic VTE 47 oncologic outcomes 47 FFR guided treatment 47 polyp recurrence 47 ANOVA 47 Afib 47 clopidogrel pretreatment 47 pharmacokinetic pharmacodynamic 47 plasma renin activity 47 pharmacokinetic characteristics 47 lipid lowering therapy 47 prospective nonrandomized 47 nocturnal hemodialysis 47 Doxil ® 47 abdominal circumference 47 nonvertebral fracture 47 P = .# 47 glycoprotein IIb IIIa inhibitors 47 antithrombotic therapy 47 myocardial viability 47 MHQP 47 urodynamic 47 bivariate analysis 47 antibody titer 47 radiographic outcomes 47 hepatic cirrhosis 47 LV dysfunction 47 subthreshold depression 47 Coronary Artery Bypass Graft 47 logistic regression analyzes 47 pharmacokinetic PK 47 multivariable analyzes 47 nonobese 47 adrenal function 47 interobserver 47 Urogenital Distress Inventory 47 LVEF 47 T1DM 47 BPH symptom 47 diagnosing ADHD 47 eplerenone 46 CHADS 2 46 adjuvant therapies 46 estimated GFR 46 serum testosterone 46 hemoglobin A1C 46 pharmacologic treatments 46 prespecified 46 Multiple logistic regression 46 logistic regression analysis 46 OPT CHF 46 MDRD equation 46 multiple logistic regression 46 periprocedural MI 46 Physical Component 46 Randomized Evaluation 46 prognostic indicators 46 allogeneic SCT 46 transcranial Doppler ultrasound 46 preoperatively 46 underwent resection 46 warfarin dosage 46 carotid IMT 46 external beam radiotherapy 46 phase IIIb 46 cranial irradiation 46 periprocedural 46 mineral density BMD 46 medication nonadherence 46 HIV HCV coinfected 46 mRS 46 retrospective cohort study 46 WOMAC scores 46 ECOG PS 46 A1c levels 46 nonoperative 46 systolic hypertension 46 upper endoscopies 46 lymphadenectomy 46 univariate analysis 46 Adjuvant chemotherapy 46 ER CHOP 46 serum IGF 46 GWTG CAD 46 serum sodium 46 visceral adiposity 46 retest reliability 46 systolic dysfunction 46 autologous SCT 46 multivariate Cox 46 radical cystectomy 46 parasitological 46 plasma cortisol 46 myocardial reperfusion 46 patient centeredness 46 thorough QT 46 #F FDG PET 46 Edinburgh Postnatal Depression 46 mycophenolate mofetil MMF 46 pCR 46 Logistic regression 46 inhospital mortality 46 eC SSRS 46 antireflux surgery 46 dyssynchrony 46 perioperative complications 46 psychiatric comorbidities 46 DAS# scores 46 nonfatal myocardial infarction MI 46 axillary node dissection 46 serum PSA 45 BioSante LibiGel Phase III 45 diabetic polyneuropathy 45 pretest 45 Multicenter AIDS 45 glomerular filtration 45 Kaplan Meier estimates 45 Randomized controlled 45 chronic hemodialysis 45 Dr. Chenchen Wang 45 thromboprophylaxis 45 Visual Analog Scale 45 liver biopsy 45 interpersonal psychotherapy 45 resected pancreatic cancer 45 myocardial revascularization 45 mRCC 45 HEDIS 45 carotid artery stenting CAS 45 Recurrent Stroke 45 polysomnogram 45 MELD scores 45 transrectal ultrasound guided 45 PSADT 45 paricalcitol 45 LAGB 45 fetal echocardiography 45 Likert 45 FDG PET scans 45 tertiles 45 Healthy Eating Index 45 radical nephrectomy 45 Coronary angiography 45 sweat chloride 45 CsA 45 Fasting glucose 45 hemoglobin concentrations 45 Multivariate analysis 45 rFVIIa 45 nondepressed 45 histological subtype 45 β blockers 45 albumin excretion 45 Zevalin consolidation 45 hsCRP 45 Seattle Angina Questionnaire 45 Apgar scores 45 tryptophan depletion 45 transient elastography 45 perfusion CT 45 multivariable logistic regression 45 MADIT CRT trial 45 conditional logistic regression 45 chemoradiation therapy 45 obese adolescents 45 neurocognitive function 45 underwent CABG 45 ENDEAVOR clinical 45 ALND 45 D Dimer 45 esophageal manometry 45 Q#IR 45 HAM D 45 fibrinolysis 45 tertile 45 IPAH 45 lymphocyte count 45 comorbid conditions 45 subclinical atherosclerosis 45 revascularization procedures 45 dietary questionnaires 45 OBPM 45 serum ferritin 45 UKPDS 45 dose melphalan 45 thyrotropin levels 45 SIMPADICO 45 MitraClip device 45 Acute Physiology 45 cytoreductive nephrectomy 45 Genant modified Sharp 45 ImmuKnow 45 HDL Selective Delipidation 45 NEO3 45 microalbumin 45 presurgical 45 % CI #.#-#.# [007] 45 Depressive Symptomatology 45 preoperative chemotherapy 44 CT perfusion 44 randomized blinded 44 alteplase 44 unpaired t 44 reinfarction 44 prostate cancer CaP 44 Comorbidity 44 ENGAGE AF TIMI 44 hsCRP levels 44 FDG PET CT 44 Wilcoxon rank sum 44 Thrombolysis 44 gallstone disease 44 semistructured interviews 44 covariates 44 QALYs 44 Prostate Specific Antigen PSA 44 Surgical resection 44 neuropsychological assessments 44 R0 resection 44 Appropriateness Criteria 44 Disease Activity 44 perioperatively 44 coronary catheterization 44 sociodemographic characteristics 44 NHAMCS 44 polysomnography 44 NCQA accreditation 44 IMPACT DCM 44 nonfasting triglyceride levels 44 serum calcium 44 carotid artery stenosis 44 adjuvant radiation 44 hemoglobin A1c 44 psychometric properties 44 GWTG 44 Univariate analysis 44 clinicopathological 44 Regression analyzes 44 Coronary artery calcium 44 MS DRGs 44 neuro cognitive 44 neurodevelopmental impairment 44 PD2i ® 44 IMPROVE HF 44 fasting lipid 44 complete cytogenetic response 44 oncological outcomes 44 Erectile function 44 Coronary calcium 44 colonography 44 specific antigen PSA 44 atrial fibrillation ablation 44 Bonferroni correction 44 warfarin therapy 44 limiting generalizability 44 Kruskal Wallis test 44 ACC AHA 44 multivariable Cox 44 mCRPC 44 screening colonoscopy 44 nomogram 44 ECOG 44 intelligence quotient IQ 44 cystoscopic 44 subanalysis 44 baseline LDH 44 dosimetric 44 variceal bleeding 44 Mental Component 44 BMI percentiles 44 RE LY ® 44 multivariable adjustment 44 warfarin dose 44 HCAHPS scores 44 microplasmin Phase III 44 State Trait Anxiety 44 concurrent ITP 44 IRLS 44 univariate analyzes 44 Functional Capacity 44 DEXA scan 44 PK PD modeling 44 recurrent VTE 44 preadmission 44 Oral NKTR 44 predictive validity 44 nonischemic cardiomyopathy 44 HER2 overexpression 44 asymptomatic carotid stenosis 44 oral glucose tolerance 44 methodologic 44 overnight polysomnography 44 T1c 44 Kaplan Meier survival 44 urolithiasis 44 SPECT MPI 44 Expanded Disability Status 44 inhibin 44 Atkins dieters cardiovascular 44 refractory ischemia 44 observational cohort study 44 imatinib therapy 44 NSTE ACS 44 FOLFIRINOX 44 Inhaled nitric oxide 44 DSM IV diagnoses 43 Depressive symptoms 43 coinfected patients 43 Numeric Rating Scale 43 ASSERT trial 43 neurodevelopmental outcomes 43 methylmalonic acid 43 risk stratification 43 CLIRS 43 postoperative pulmonary 43 Wechsler Adult 43 Patient Satisfaction Survey 43 CALGB 43 TVAAS 43 Viral load 43 IQR 43 audiometric 43 NWEA MAP 43 perioperative morbidity 43 cirrhotic CHC patients 43 FDG PET 43 serum HBV DNA 43 thyroglobulin 43 fasting triglyceride levels 43 BFPET 43 univariate 43 renal biopsy 43 ALLHAT 43 NAEP math 43 bivariate 43 hepatitis C genotype 43 noncardiac 43 preoperative MRI 43 budesonide MMX Phase III 43 SKAMP D 43 Post hoc 43 thrombocytopenic 43 nonalcoholic steatohepatitis 43 stage IIIb IV 43 functional mitral regurgitation 43 HBsAg 43 EuroSCORE 43 Cronbach 43 coronary revascularization 43 multicentre prospective 43 adjuvant radiotherapy 43 HORIZONS AMI trial 43 undergoing liver transplantation 43 subtest 43 confirmed CCyR 43 EGFR mutation status 43 adenoidectomy 43 atherothrombotic disease 43 hematological parameters 43 troponin T 43 logistic regression model 43 MGN# 43 Scale Cognitive Subscale 43 curative resection 43 Glycemic Control 43 Tumor Response 43 prospective longitudinal 43 HIV tropism 43 chi squared 43 VCUG 43 differentiate squamous 43 creatinine levels 43 tumor recurrence 43 clinico pathological 43 QRISK 43 mammographic density 43 inter rater reliability 43 Arch Intern Med 43 MELD score 43 NT proBNP 43 perceptual reasoning 43 somatoform disorders 43 Framingham Offspring Study 43 Polysomnography 43 residual platelet reactivity 43 VTE prophylaxis 43 decompensated cirrhosis 43 Kaplan Meier analysis 43 bladder carcinoma 43 SUVmax 43 Congenital Heart Surgery 43 EDSS 43 Cognitive Abilities Test 43 preoperative evaluation 43 GWTG Stroke 43 KRAS status 43 Lung transplantation 43 syndromal 43 beta blocker therapy 42 Recurrence Score 42 NCT# ClinicalTrials.gov 42 allogeneic transplantation 42 Poisson regression 42 perioperative mortality 42 intraclass correlation coefficients 42 chemoradiotherapy 42 quantitative gene expression 42 Child Behavior Checklist 42 microsatellite instability 42 CLIRS trial 42 undergoing radical prostatectomy 42 kidney allograft 42 Decitabine 42 AlloMap test 42 Acute Stroke 42 adjuvant tamoxifen 42 MDRD 42 neoadjuvant treatment 42 biostatistical analysis 42 BLLs 42 distant metastasis 42 adjuvant chemotherapy 42 perinatal outcomes 42 comorbidities 42 thrombophilia 42 pancreatic fistula 42 pretransplant 42 HoLEP 42 BEXXAR Therapeutic Regimen 42 ICD implantation 42 neoadjuvant chemotherapy 42 allogeneic hematopoietic stem cell 42 nondiabetics 42 ACS NSQIP 42 Fontan procedure 42 percutaneous vertebroplasty 42 diagnostic workups 42 NHANES III 42 biostatistical 42 empiric therapy 42 coronary CTA 42 nonpregnant women 42 SHPT 42 preserved ejection fraction 42 T1a 42 pacemaker implantation 42 pulmonary artery catheterization 42 left ventricular systolic 42 HYVET 42 Economically disadvantaged students 42 glomerular filtration rate 42 Renal dysfunction 42 EmbraceAC 42 CMV disease 42 recombinant PSMA vaccine 42 acute myocardial infarction MI 42 disease progression TTP 42 STEP BD 42 histopathological 42 adjuvant endocrine therapy 42 acute cholecystitis 42 ejection fractions 42 potent antiretroviral therapy 42 thrombus aspiration 42 Prehypertension 42 Vectra DA 42 decompensated heart failure 42 MTWA testing 42 PLCO 42 cranial radiation 42 diagnostic angiography 42 VerifyNow P#Y# 42 BMI ≥ 42 Acute Myeloid Leukaemia AML 42 CardioPET 42 Comparative effectiveness 42 multivariate statistical 42 colonoscopic 42 liver transplant recipients 42 mutated K ras 42 azacitidine 42 postmarket safety 42 hepatorenal syndrome 42 nonoperative treatment 42 postmarketing surveillance 42 Phase IIIb study 42 adjuvant tamoxifen therapy 42 diagnosing coronary artery 42 Heavy menstrual bleeding 42 pharmacodynamic endpoints 42 UPPP 42 anti JCV antibody 42 Mantel Haenszel 42 GIK infusion 42 histologically proven 42 portal vein thrombosis 42 recurrent miscarriage 42 System IPSS 42 AMOR IPAT 42 multivariable regression 42 Median survival 41 nonfatal MI 41 Prostate Specific Antigen 41 semistructured interview 41 stratify patients 41 endoscopist 41 thrombolytic therapy 41 carotid artery blockage 41 prognostic factors 41 QOPI 41 Perceived Stress Scale 41 genotoxicity reproductive toxicology 41 ECLS 41 longitudinal observational study 41 BRCA2 mutation carriers 41 pharmacodynamic markers 41 prospective observational cohort 41 stepwise logistic regression 41 correlation coefficients 41 IDET procedure 41 genomewide 41 QIDS 41 causal inference 41 TACE 41 MDCT scans 41 PCI ExTRACT TIMI 41 Adjuvant therapy 41 preceptorship 41 Estrogen Receptor 41 Pegylated Interferon 41 parenteral antibiotics 41 TQT 41 nodal dissection 41 antimicrobial prophylaxis 41 Descriptive statistics 41 ofpatients 41 Mastery Test 41 microalbuminuria 41 NAFLD 41 allele frequencies 41 transthoracic echocardiography 41 postsurgical 41 CareFocus 41 allogenic stem cell 41 CA9 SCAN 41 psychodynamic therapy 41 acute mania 41 Breslow thickness 41 venous thromboembolism prophylaxis 41 TOP2A 41 wedge resection 41 radiofrequency catheter ablation 41 PROMETA protocols 41 periodically reassessed 41 ELBW infants 41 ovarian cancer biomarker 41 QuickOpt 41 Kidney Disease Outcomes 41 epoetin alfa 41 lipoprotein levels 41 endoscopic examinations 41 coronary CT angiography 41 Pearson correlation coefficients 41 pediatric liver transplants 41 MelaFind R 41 bronchial reactivity 41 neuropsychological tests 41 intraoperative ultrasound 41 ependymoma 41 psychometrically sound 41 #.#ng/ml 41 Baseline characteristics 41 ITBS 41 TEVAR 41 TKAs 41 EMPOWER TM 41 multicenter randomized controlled 41 PCPT 41 pelvic ultrasound 41 operable breast cancer 41 ± SD 41 nulliparous women 41 OPCAB 41 UPDRS II 41 revision hip arthroplasty 41 colectomy 41 cytogenetic response 41 underwent bariatric surgery 40 baseline A1C 40 blood counts CBCs 40 boards IRBs 40 hepatectomy 40 Wisconsin Sleep Cohort 40 International Prognostic Scoring 40 MPCP 40 mechanistic studies 40 Prostate Cancer Prevention 40 HAART initiation 40 KRAS mutation 40 nonmetastatic 40 Solid Tumors RECIST 40 PRIMO CABG 40 Hypertrophy 40 graft patency 40 novel antifolate currently 40 nationally normed test 40 intravenous thrombolysis 40 vWD 40 geologic interpretations 40 noncardiovascular 40 posterior lumbar interbody fusion 40 Follicular Lymphoma 40 hospitalwide 40 μg liter 40 axillary dissection 40 Framingham Risk Score 40 Patient Registry 40 asymptomatic hyperuricemia 40 LeadCare II 40 Doppler sonography 40 INTERMACS 40 Rigorous scientific 40 renal cell carcinomas 40 TAXUS ARRIVE 40 substance induced psychosis 40 AVERROES 40 co morbidities 40 neuropsychological evaluations 40 diagnostic workup 40 chemotherapeutic regimen 40 HCAHPS survey 40 ERBITUX infusion 40 Commended Performance 40 ICD implantations 40 SLNB 40 blinded randomized controlled 40 DIBELS 40 longitudinal cohort study 40 poststroke depression 40 www.hospitalcompare.hhs.gov 40 immunosuppressive regimens 40 ELBW 40 CMMI maturity 40 immunochemical fecal occult 40 SWOG 40 Carotid artery stenting 40 Liver biopsy 40 Scheuermann kyphosis 40 internalizing behaviors 40 Complication rates 40 acute leukemias 40 nonsquamous 40 AZ Learns 40 adiponectin concentrations 40 % CI #.#-#.# [005] 40 APEX AMI 40 SCr 40 patients 40 5q deletion 40 pharmacoeconomic analysis 40 Sentinel Lymph Node Biopsy 40 Kyphon Balloon Kyphoplasty 40 allogeneic transplant 40 prospective multicenter study 40 CVD mortality 40 Kruskal Wallis 39 eGFR 39 neuropsychological testing 39 assigns numeric 39 DSST 39 WKCE 39 sonographic examination 39 symptom onset 39 neuro psychological 39 HIV RDEA# 39 ipsilateral stroke 39 MYTHOS trial 39 Phase IIb III 39 undergoing CABG 39 Glomerular Filtration Rate 39 STEMI patients 39 HOMA scores 39 Colorectal cancer screening 39 EPDS 39 Mandometer 39 thoracoscopic lobectomy 39 transcatheter aortic valve implantation 39 primary percutaneous coronary 39 tuberculin skin testing 39 adverse cytogenetics 39 postapproval 39 ejection fraction 39 CMV infection 39 Eisenmenger syndrome 39 OPTIMIZE HF 39 pancreatectomy 39 Patient Satisfaction 39 isokinetic 39 QTinno TM 39 highest tertile 39 Norm Referenced Test 39 sleeve lobectomy 39 empirically validated 39 DCE MRI 39 enzymatic assay 39 MAQC 39 Neoadjuvant 39 polysomnography PSG 39 OnDose TM 39 metastatic lung cancer 39 Neuropsychological Status 39 rALLy trial 39 CABG 39 statin medications 39 esophageal varices 39 MADIT II 39 revascularization procedure 39 invasive prenatal 39 micronutrient supplementation 39 axillary node 39 Torisel 39 morbidly obese adolescents 39 genomic biomarker 39 colonoscopy flexible sigmoidoscopy 39 ventilator weaning 39 congenital toxoplasmosis 39 cTnT levels 39 radioiodine therapy 39 Appendix VII 39 inhospital 39 fraternal twin pairs 39 SYMMETRY trial 39 RightStart 39 esophagectomy 39 Scale EDSS score 39 Multivariate analysis revealed 39 colorectal cancer CRC 39 perinatal mortality 39 ventricular function 39 endoscopic retrograde cholangiopancreatography ERCGrant Parpan 39 Hydroxyurea