Related by context. All words. (Click for frequent words.) 64 postintervention 62 postoperative mortality 62 oncologic outcomes 62 preintervention 62 tubular diskectomy 62 perioperative mortality 62 hepatic resection 62 radical cystectomy 61 chemoradiation therapy 61 clinically localized prostate 61 hepatectomy 60 postoperative morbidity 60 Radical prostatectomy 60 pancreatic resection 60 rFSH 59 lymphadenectomy 59 pelvic lymphadenectomy 59 postoperative chemotherapy 59 Operative mortality 59 TKAs 59 postoperative complication 59 liver resection 59 EDSS scores 59 HbA 1c levels 59 PSA nadir 59 radical nephrectomy 58 nephron sparing surgery 58 OPCAB 58 external beam radiotherapy 58 cytoreductive nephrectomy 58 definite stent thrombosis 58 posttreatment 58 cystectomy 58 biochemical relapse 58 univariate analysis 58 microdebrider 58 nondiabetic patients 58 primary patency 57 nephrectomy 57 preoperative chemotherapy 57 interquartile range 57 radical prostatectomy 57 androgen suppression 57 abdominal hysterectomy 57 p = #.# [003] 57 PASI scores 57 TURBT 57 ovulation induction 57 subtrochanteric 57 CABG surgeries 57 periprocedural 57 adenoma recurrence 57 underwent radical prostatectomy 57 nonmetastatic prostate cancer 57 vaginal hysterectomy 57 coronary revascularization procedures 57 inguinal hernia repair 57 HoLEP 57 biochemical recurrence 57 CR nPR 56 BRCA2 mutation carriers 56 parathyroidectomy 56 sacrocolpopexy 56 MMSE scores 56 TURP 56 laparoscopic cholecystectomy 56 bariatric procedure 56 carotid artery stenting CAS 56 risk reducing salpingo 56 UPPP 56 cytoreduction 56 perioperative morbidity 56 trabeculectomy 56 percutaneous vertebroplasty 56 laparoscopic nephrectomy 56 PCIs 56 lymph node dissection 56 radioiodine therapy 56 adrenalectomy 56 ER CHOP 56 paclitaxel eluting stents 56 patients undergoing CABG 56 interstitial brachytherapy 56 ICSI cycles 56 Coronary artery bypass grafting 56 total knee arthroplasties 56 nephrectomies 56 postdischarge 56 univariate analyzes 56 total abdominal hysterectomy 56 advanced neoplasia 56 knee arthroplasty 56 HBeAg seroconversion 55 debulking surgery 55 radical prostatectomy RP 55 thyroidectomy 55 laparotomy 55 P = .# 55 perioperative complications 55 ELBW infants 55 revascularization procedures 55 intravenous diuretics 55 pump CABG 55 nonoperative 55 multivariate analyzes 55 paracentesis 55 CIN3 55 % CI #.#-#.# [003] 55 nonoperative treatment 55 adenoma detection 55 HSCT 55 NIHSS score 55 GnRH agonist 55 intravitreal injections 55 CYPHER Stent 55 MACCE 55 calcaneal fractures 55 pCR 55 serum estradiol 55 Coronary artery bypass graft 55 VATS lobectomy 55 MMSE score 55 pelvic lymph node dissection 55 psychiatric comorbidities 55 GnRH agonists 55 lung resection 55 colectomy 55 tumor resection 55 polyp detection 55 underwent CABG 55 cardiopulmonary bypass CPB 55 primary percutaneous coronary 55 cerebral angiography 55 bolus dose 55 % CI #.#-#.# [008] 55 pneumonectomy 55 lipid lowering agents 55 elective PCI 55 MitraClip device 55 postprocedure 54 coronary artery bypass grafting 54 % CI #.#-#.# [007] 54 % Confidence Interval 54 suicide attempters 54 p = .# [002] 54 R0 resection 54 potent antiretroviral therapy 54 insulin detemir 54 cytoreductive surgery 54 symptomatic carotid stenosis 54 endoscopists 54 preoperative radiotherapy 54 renal tumors 54 logistic regression models 54 gauge vitrectomy 54 dose Iluvien 54 androgen deprivation 54 multivariable analysis 54 autologous chondrocyte implantation 54 epidural analgesia 54 fragility fracture 54 oral anticoagulant therapy 54 hemoglobin A1c levels 54 everolimus eluting stents 54 angiographic restenosis 54 myocardial revascularization 54 coronary revascularization 54 bariatric surgical 54 pulmonary dysfunction 54 beta blocker therapy 54 APTIVUS r 54 multivariate Cox 54 CI #.#-#.# [001] 54 nonobese 54 femoral neck fractures 54 hip BMD 54 kidney allograft 54 oral anticoagulation 54 ALND 54 antibiotic regimens 54 serum lipid levels 54 p = NS 54 preoperative PSA 54 lobectomies 54 EDSS score 54 pulmonary artery banding 54 Poisson regression 54 postoperative complications 54 dacarbazine chemotherapy 54 cystoscopic 54 ALT elevation 54 PRADAXA #mg 54 logistic regression model 54 serum urate 54 conventional angiography 54 recanalization 54 endometrial thickness 54 Doxil ® 54 partial nephrectomy 54 LVRS 54 adenotonsillectomy 54 sympathectomy 54 CI -#.# 54 underwent resection 54 revascularization procedure 54 lipid lowering therapy 54 histologically confirmed 54 relapsed MM 54 F FDG PET 54 ALT flares 53 mitral valve replacement 53 μg liter 53 Cardiopulmonary bypass 53 atherosclerotic renal artery stenosis 53 virological response 53 plasma cortisol 53 HbA1C levels 53 endotracheal intubation 53 transurethral resection 53 cataract extraction 53 flutamide 53 Bonferroni correction 53 locoregional 53 total knee arthroplasty 53 angiographies 53 IOP lowering 53 thromboprophylaxis 53 methotrexate monotherapy 53 femoral shaft fracture 53 axillary node dissection 53 nulliparous women 53 ANCOVA 53 conditional logistic regression 53 VAD implantation 53 mg kg dose 53 nonvertebral fractures 53 KRAS mutations occur 53 LNG IUS 53 pancreatectomy 53 reperfusion therapy 53 logistic regression analysis 53 VLBW infants 53 Lumbar spine 53 follicular phase 53 coronary angiograms 53 thoracoscopic lobectomy 53 Kaplan Meier estimates 53 TMC# r 53 logistic regression analyzes 53 amoxicillin clavulanate 53 VTE prophylaxis 53 renal transplants 53 Kaplan Meier analysis 53 CORE OM 53 chronic hemodialysis 53 divalproex sodium 53 euthyroid 53 ovarian stimulation 53 colorectal neoplasia 53 nondepressed 53 intravesical therapy 53 diagnostic angiography 53 nonfatal MI 53 dalteparin 53 NATRECOR ® 53 hypofractionated radiation 53 penetrating keratoplasty 53 arterial grafts 53 coronary stenting 53 Phacoemulsification 53 transthoracic echocardiography 53 pegylated interferon alfa 53 angioplasty stenting 53 evaluable subjects 53 surgical excision 52 enucleation 52 chemoradiotherapy 52 comorbid illnesses 52 Breast conserving 52 unsedated colonoscopy 52 cholecystectomy 52 timepoints 52 % CI #.#-#.# [005] 52 ICD therapy 52 XIENCE V demonstrated 52 tapentadol ER 52 HIPEC 52 donor nephrectomy 52 femoral neck fracture 52 corticosteroid dose 52 symptomatic VTE 52 percutaneous drainage 52 inpatient hospitalizations 52 aldosterone antagonist 52 DAPT 52 carotid stenosis 52 recombinant FSH 52 recurrent VTE 52 solifenacin 52 NNT = 52 FFR guided 52 MADRS score 52 β blockers 52 Subgroup analysis 52 antiretroviral naïve 52 extensive metabolizers 52 hepatorenal syndrome 52 CPAP adherence 52 guideline concordant 52 Score DAS# 52 eplerenone 52 care regimens CCR 52 hsCRP levels 52 pulsatile flow 52 mg BID dose 52 iPTH 52 NSTEMI 52 multivariate logistic regression 52 estimated GFR 52 foveal thickness 52 helical CT 52 ovulatory 52 severe exacerbations 52 MDRD 52 esophagectomy 52 tipranavir r 52 pelvic prolapse 52 undetectable HBV DNA 52 endarterectomy 52 CC genotype 52 lymphocytosis 52 transfemoral 52 colorectal adenoma 52 operable pancreatic cancer 52 total hip arthroplasty 52 surgical revascularization 52 sociodemographic characteristics 52 undergoing radical prostatectomy 52 undergone radical prostatectomy 52 serum PSA 52 TLIF 52 NATRECOR R 52 aged ≥ 52 ENGAGE AF TIMI 52 oophorectomy 52 serum concentrations 52 Index CDAI 52 estimated glomerular filtration 52 nonadherent 52 PSADT 52 morphometric vertebral fractures 52 Non inferiority 52 % CI #.#-#.# [004] 52 coronary arteriography 52 advanced adenoma 52 invasive coronary angiography 52 chronic LBP 52 balloon valvuloplasty 52 partial meniscectomy 52 multivariable logistic regression 52 spine fusions 52 spirometric 52 SCIg 52 transrectal ultrasound guided 52 nonobstructive CAD 52 gadolinium enhanced 52 ipsilateral stroke 52 liver histology 52 pacemaker implantation 52 lamivudine monotherapy 52 enhanced sonography 52 serum phosphate 52 interferon ribavirin 52 prostate cancer CaP 52 IFN alfa 51 Patency 51 placebo dexamethasone 51 electrical cardioversion 51 epithelial ovarian cancer 51 QALE 51 cecal intubation 51 hypogonadal men 51 biologic DMARDs 51 posttransplant 51 extracorporeal circulation 51 multiple logistic regression 51 comorbid conditions 51 transesophageal echocardiography 51 candidemia 51 Carotid stenting 51 virologic response 51 prospectively defined 51 prevalences 51 neoadjuvant 51 extubation 51 PCA3 scores 51 PCa 51 conventional coronary angiography 51 NMIBC 51 liver biopsies 51 ejection fractions 51 baseline LDH 51 screening colonoscopy 51 virologic failure 51 hemodilution 51 seroconverted 51 neoadjuvant chemotherapy 51 paroxysmal AF 51 ziprasidone 51 perioperatively 51 ECD kidneys 51 prostate brachytherapy 51 QTcF 51 NHANES III 51 artery bypass 51 comorbid disorders 51 abnormal cytology 51 elevated LDH 51 catheterisation 51 hMG 51 systemic corticosteroids 51 concurrent chemoradiation 51 DCCT 51 symptom exacerbation 51 ofpatients 51 adjuvant tamoxifen 51 carotid artery stenting 51 Export Aspiration Catheter 51 histologically proven 51 randomized controlled trials RCTs 51 antibiotic prophylaxis 51 allogeneic HSCT 51 serum creatinine levels 51 transthoracic 51 SYNTAX trial 51 IQR 51 LV dysfunction 51 distal radial fractures 51 colorectal liver metastases 51 symptomatic BPH 51 laparoscopic technique 51 breast carcinoma 51 colonoscopic 51 LDLT 51 TT genotype 51 Serum creatinine 51 Baseline characteristics 51 endoscopic sinus surgery 51 IPAH 51 reintervention 51 randomizing patients 51 IELT 51 5-FU/LV 51 NNRTI resistance 51 CABG 51 dexmedetomidine 51 aortic root replacement 51 recurrent venous thromboembolism 51 extracapsular extension 51 CVD mortality 51 premenopause 51 needleless connectors 51 prostate carcinoma 51 gastrectomy 51 argatroban 51 undergoing CABG 51 LMWH 51 myocardial reperfusion 51 5-fluorouracil/leucovorin 51 advanced adenomas 51 genotypic resistance 51 specific antigen PSA 51 cannulation 51 psychiatric morbidity 51 colorectal carcinomas 51 transarterial chemoembolization 51 hepatitis C genotype 51 baseline HbA1c 51 pretransplant 51 autologous SCT 51 ketorolac 51 de novo AML 51 catheter ablations 51 tertile 51 laparoscopic partial nephrectomy 51 Multicenter AIDS 51 Watchful Waiting 51 intravaginal ejaculatory latency 51 lowest tertile 51 PCI percutaneous coronary 51 Tumor Response 51 afterload 51 anticoagulation therapy 51 radiotherapy RT 51 HER2 positive cancers 51 allogeneic hematopoietic stem cell 51 retroperitoneal 51 Hb A1C 51 duplex ultrasonography 51 laparoscopic hysterectomy 51 robotic prostatectomy 51 postoperative hemorrhage 51 comorbidity 51 acetabular components 51 experienced virologic failure 51 metastatic RCC 51 NSTE ACS 51 retrospectively analyzed 51 urethral strictures 51 salmeterol fluticasone 51 prospectively randomized 50 lobectomy 50 CCyR 50 venous thromboembolism prophylaxis 50 incomplete revascularization 50 operable breast cancer 50 vertebral fracture 50 Fontan procedure 50 GH deficiency 50 glomerular filtration 50 metastatic lung cancer 50 LUTS 50 % CI #.#-#.# [006] 50 MIRAPEX 50 OGTT 50 MS DRGs 50 ADAS cog 50 endometrial carcinoma 50 prospective nonrandomized 50 Desferal 50 nonfasting triglyceride levels 50 seminal vesicle invasion 50 dosage regimens 50 adjunctive placebo 50 serum testosterone 50 certolizumab 50 mIU ml 50 percutaneous intervention 50 paroxysmal atrial fibrillation 50 mg/m2 cohort 50 Logistic regression 50 thrombocytopenic 50 postoperative atrial fibrillation 50 fluticasone salmeterol 50 biologic DMARD 50 air insufflation 50 highest tertile 50 oncological outcomes 50 SpO 2 50 varicoceles 50 urodynamic parameters 50 bariatric procedures 50 coronary calcification 50 receiving VICTRELIS 50 venography 50 chemoembolization 50 glycated hemoglobin levels 50 bypass grafting 50 mg/m2 dose 50 platelet reactivity 50 pulmonary resection 50 HIV HCV coinfected 50 PCWP 50 symptomatic hyponatremia 50 titrated glipizide 50 dysglycemia 50 pancreatic adenocarcinoma 50 antihypertensive therapy 50 neurologic complications 50 Zevalin consolidation 50 treat NNT 50 unfractionated heparin 50 STEMI patients 50 retrospective cohort 50 retrospective cohort study 50 HbA1c levels 50 perfusion abnormalities 50 percutaneous transluminal coronary angioplasty 50 Hormonal therapy 50 retrospective observational study 50 randomized multicenter trial 50 anagrelide 50 immunocompetent 50 odds ratios ORs 50 carotid artery stenosis 50 seropositivity 50 steroid dexamethasone 50 carotid IMT 50 conjugated equine estrogen 50 serum calcium levels 50 femoral neck BMD 50 observational cohort 50 aminotransferase elevations greater 50 efficacy evaluable 50 concomitant AEDs 50 incontinence episodes 50 achieved sustained virological 50 acromegalic patients 50 dose cohort 50 systemic corticosteroid 50 neurocognitive function 50 mcg albinterferon alfa 2b 50 eculizumab therapy 50 fibrinolysis 50 Kaplan Meier method 50 darunavir ritonavir 50 coronary angiography 50 pulmonary artery catheter 50 T2DM 50 ischemic mitral regurgitation 50 tacrolimus ointment 50 warfarin therapy 50 liver transplant recipients 50 recurrent GBM 50 pulmonary angiography 50 crossclamp 50 XIENCE V PROMUS Stent 50 REYATAZ r arm 50 nadolol 50 percutaneous interventions 50 overt nephropathy 50 macroalbuminuria 50 pharmacokinetic characteristics 50 interobserver 50 lipid lowering drugs 50 tolterodine 50 T2 lesions 50 chemoradiation 50 PLCO 50 paricalcitol 50 singleton pregnancies 50 fibrinolytic therapy 50 confidence interval #.#-#.# 50 HIV uninfected 50 ASCT 50 virologic responses 50 LTBI 50 alanine aminotransferase ALT 50 postinjury 49 methotrexate therapy 49 virologic breakthrough 49 treated nonsurgically 49 stage IIIB 49 colorectal cancer incidence 49 symptomatic intracranial hemorrhage 49 MetS 49 Gamma Knife surgery 49 clinicopathological features 49 chronic GVHD 49 postoperatively 49 intravascular ultrasonography 49 INRs 49 HER2 expression 49 coronary interventions 49 cinacalcet 49 Acute Decompensated Heart Failure 49 secondary efficacy endpoint 49 prospective observational cohort 49 efavirenz EFV 49 androgen suppression therapy 49 reoperation 49 epidural anesthesia 49 FOLPI 49 preserved LVEF 49 alteplase 49 deferoxamine 49 androgen ablation 49 coinfected patients 49 TACE 49 XELOX 49 sustained virological response 49 ± SD 49 cardiopulmonary bypass 49 polytherapy 49 transaminase levels 49 neurologic sequelae 49 imipenem 49 coronary artery bypass grafts 49 postoperative 49 tirofiban 49 BPH LUTS 49 #mg q8h 49 elevated troponin 49 atrophic gastritis 49 endoscopic retrograde cholangiopancreatography ERCGrant Parpan 49 relapsed AML 49 ritonavir boosted 49 VADT 49 atazanavir ritonavir 49 Flu Cy 49 Crohn Disease Activity 49 ureteroscopy 49 TAXUS Express Stent 49 intra abdominal abscess 49 surgical interventions 49 dose escalation phase 49 acetabular fracture 49 thrombolytic therapy 49 oxygen desaturation 49 nondiabetic 49 DEXA scan 49 familial aggregation 49 psychiatric outpatients 49 stable angina 49 cerebral microbleeds 49 corticosteroid therapy 49 brachial artery flow 49 dosing frequency 49 Readmission 49 Free Survival PFS 49 dual antiplatelet therapy 49 HIV seronegative 49 TEMODAL 49 anovulatory 49 TMP SMX 49 underwent liver transplantation 49 pamidronate 49 thrombus aspiration 49 BMD measurements 49 reteplase 49 Screening Trial 49 serum homocysteine 49 vasopressor 49 cytotoxic chemotherapy 49 TEAEs 49 mitral valve repair 49 histologically 49 heterozygotes 49 rt PA 49 severe neutropenia 49 mITT population 49 prospective multicenter study 49 antimicrobial prophylaxis 49 CABG procedures 49 visceral metastases 49 Kruskal Wallis test 49 loop diuretics 49 sacral nerve stimulation 49 DAS# scores 49 normotensive 49 Multivariate analyzes 49 pathologic fractures 49 Apgar scores 49 reintubation 49 dysfunctional voiding 49 attain statistical significance 49 CK # plasma concentrations 49 COPD exacerbation 49 atrioventricular block 49 angiographically 49 tenecteplase 49 aortic crossclamp 49 BMI z 49 lymphocyte count 49 revision hip arthroplasty 49 immunosuppression therapy 49 STN DBS 49 RE LY ® 49 ug kg 49 antiangiogenic therapy 49 arteriography 49 ARIXTRA 49 moderately emetogenic 49 rHuEPO 49 nonelective 48 concomitant medications 48 euthymic patients 48 glycated hemoglobin HbA1c 48 functional mitral regurgitation 48 valve implantation 48 pegylated interferon alfa 2b 48 recurrent endometrial cancer 48 inotropic 48 T1DM 48 CABG surgery 48 multivariable adjustment 48 parous 48 Mechanical ventilation 48 neurodevelopmental impairment 48 nonsignificant difference 48 urothelial cancer 48 #.#ng/ml 48 post operatively 48 isolated systolic hypertension 48 peak VO2 48 affective psychosis 48 BRCA mutation carriers 48 cells mcL 48 amenorrhoea 48 ABC/3TC 48 unipolar depression 48 psychiatric comorbidity 48 Carotid endarterectomy 48 CsA 48 NAVISTAR R 48 AGILECT R 48 postoperative bleeding 48 ACR Pedi 48 nonunions 48 subscale scores 48 rebleeding 48 renal transplantation 48 onset diabetes mellitus 48 nonsignificant 48 post thrombotic syndrome 48 Radio Frequency Ablation 48 comorbidities 48 retinal thickness 48 symptomatic intracranial 48 FDA defined valvulopathy 48 glycoprotein IIb IIIa inhibitors 48 elective percutaneous coronary 48 ELBW 48 clinico pathological 48 null responder HCV 48 observational cohort study 48 LRTI 48 UPDRS scores 48 undergoing coronary angiography 48 ß blockers 48 adiponectin concentrations 48 virological failure 48 Pemetrexed 48 cytogenetic response 48 gynecologic procedures 48 inhaled budesonide 48 pretreatment baseline 48 systolic dysfunction 48 RBC transfusions 48 interrater 48 elevated serum creatinine 48 metabolic parameters 48 low dose cytarabine 48 antihypertensive medications 48 chemotherapeutic regimen 48 cortical activation 48 therapeutic regimens 48 mL kg 48 Febrile neutropenia 48 left ventricular systolic 48 oral olanzapine 48 endoscopist 48 postoperative AF 48 thoracoscopic 48 intravenous vancomycin 48 PCNL 48 tumor histology 48 chest radiographs 48 Aquadex 48 Vasotrac 48 ZYVOX 48 seminomas 48 suboptimal adherence 48 subclinical hypothyroidism 48 sirolimus eluting stents 48 bivariate analyzes 48 hemodynamically significant 48 LASIK procedures 48 graft patency 48 μmol L 48 dyslipidaemia 48 ml min 48 dose statin therapy 48 prostate TURP 48 pulmonary capillary wedge 48 intravenous dosing 48 timepoint 48 echocardiographic parameters 48 AZOR 48 undergoing bariatric surgery 48 subanalysis 48 urologic surgeons 48 nicardipine 48 protease inhibitor PI 48 PET CT scanning 48 atrial fibrillation ablation 48 Feasibility Trial 48 HYVET 48 sevelamer 48 maximal doses 48 lumbar fusion 48 pegylated liposomal doxorubicin 48 hypoglycemic events 48 endoscopic remission 48 HAQ DI 48 HIV seroconversion 48 titration phase 48 hematopoietic cancers 48 nonsurgical treatments 48 percutaneous coronary interventions 48 neutrophil counts 48 serum PTH 48 coronary intervention 48 Osteoporotic Fractures 48 calculated creatinine clearance 48 WOMAC pain 48 hemodialysis patients 48 EURIDIS 48 MADIT CRT trial 48 graft dysfunction 48 serum HCV RNA 48 HORIZONS AMI trial 48 plasma creatinine 48 acetazolamide 48 Angiox R 48 bowel resection 48 syndromal 48 mean ± SEM 48 carotid artery stent 47 chronic periodontitis 47 Visual Analogue Scale VAS 47 DSM IV diagnosis 47 DMARD therapy 47 prognostic variables 47 atherothrombotic disease 47 GYTS 47 bone allografts 47 hippocampal volumes 47 underwent bariatric surgery 47 Prograf ® 47 mL/min/#.# m2 47 thrombolysis 47 fistula closure 47 dobutamine 47 thymectomy 47 nonpsychotic 47 NSABP B 47 progression TTP 47 noncardiac surgery 47 NIH CPSI 47 echocardiographic 47 scalpel vasectomy 47 carotid surgery 47 #mg doses [002] 47 severe hypoglycaemia 47 Liver transplantation 47 elevated ALT 47 cirrhotic patients 47 LS BMD 47 immunosuppressive medications 47 MS DRG 47 pulmonary artery catheterization 47 abdominal adiposity 47 mm ³ 47 null responder 47 HALO# [002] 47 tiotropium 47 thrombolytics 47 MIRAPEX ER 47 radiographic progression 47 doxorubicin cyclophosphamide 47 AF ablation 47 oral prednisolone 47 DMIST 47 sociodemographic factors 47 prevalent vertebral fracture 47 serum IGF 47 concomitant antibiotics 47 nocturnal awakenings 47 doxorubicin docetaxel 47 intravenous tPA 47 RECIST criteria 47 ablation procedures 47 LEXIVA r 47 HGPIN 47 metastatic GIST 47 heavily pretreated patients 47 fluorescence cystoscopy 47 Wistar rats 47 peri procedural 47 oral hypoglycemic agent 47 endocrine therapies 47 sentinel node biopsy 47 luteal phase 47 systemic hypotension 47 IL#B 47 ICD shocks 47 proton MR spectroscopy 47 racemic albuterol 47 Hypotension 47 IFN beta 47 Lucentis ranibizumab Genentech 47 Venous thromboembolism 47 lactate dehydrogenase 47 asthma exacerbation 47 VO2 peak 47 AIR2 Trial 47 bivariate 47 nonrandomized 47 cryptogenic stroke 47 abdominal laparoscopic surgery 47 Subgroup analyzes 47 microbiologically evaluable 47 oral hypoglycemic agents 47 ventricular enlargement 47 FOSRENOL ® 47 urinary incontinence UI 47 comorbid diagnoses 47 longitudinal cohort study