MSH6

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(Click for frequent words.) 73 MLH1 69 MSH2 65 PALB2 65 PTPN# 64 GSTP1 64 receptor tyrosine kinase 63 variant allele 63 succinate dehydrogenase 62 TSC2 62 CHEK2 62 LRAT 62 TSC1 62 CDKN2A 62 SMN1 61 Activating mutations 61 Chromosomal 61 CDH1 61 constitutively expressed 61 cell adhesion molecule 61 polycystin 61 heterozygotes 61 MTHFR 61 BRCA1 BRCA2 61 microsatellite instability 61 C#Y 61 lysine residues 61 ERBB2 61 methyltransferase 60 variant alleles 60 RRM1 60 pRb 60 ubiquitinated 60 wildtype 60 ABCB1 60 microdeletions 60 rs# [004] 60 heterozygous 59 COL#A# 59 ribosomal protein 59 intermediate filaments 59 Transgenic Mice 59 missense mutations 59 Polymorphisms 59 Clusterin 59 cystic fibrosis transmembrane conductance 59 Upregulation 59 chromosome #q 59 mRNA expression 59 MDA MB 59 TYMS 59 FGFR3 59 ERCC1 59 TACI 59 HFE gene 59 evolutionarily conserved 59 #q# [001] 59 #p#.# [002] 59 transthyretin 59 cytokeratin 59 p# mutations 59 BRAF V#E 59 proto oncogene 59 endonuclease 59 GNAQ 59 promoter methylation 59 Homozygous 59 BRAF protein 59 Histone 59 matrix metalloproteinase 59 PTEN gene 58 metalloproteinase 58 subcellular localization 58 Phosphorylation 58 TOP2A gene 58 tumor suppressor gene 58 HNPCC 58 forkhead 58 rs# [001] 58 MTHFR gene 58 GSTT1 58 BMP2 58 germline mutations 58 rRNA 58 SLC#A# [001] 58 methylenetetrahydrofolate reductase 58 BRCA2 58 CYP#C# [002] 58 CFTR gene 58 JAK2 gene 58 deacetylation 58 synthases 58 Drosha 58 SCN5A 58 P2X 58 HepG2 cells 58 somatic mutations 58 substrate specificity 58 heterozygosity 58 MLL gene 58 connexin 58 NKX#.# 58 ribosomal proteins 58 coding genes 58 NFKBIA 58 #q# [002] 58 #q#.# [001] 58 PIK3CA 58 TIMP 58 NPC1 58 FGFR4 58 caveolin 1 58 BRCA2 gene 58 androgen receptor AR 58 syngeneic 58 genes encoding 58 DU# [002] 58 p# tumor suppressor 58 allelic 58 tyrosine kinase receptor 58 At#g# 57 PDGFR 57 CAG repeats 57 constitutively activated 57 ankyrin repeat 57 missense 57 c KIT 57 cyclin E 57 proapoptotic 57 chromosome #q#.# [001] 57 GSTM1 57 T#M 57 phosphorylates 57 MnSOD 57 mtDNA mutations 57 BRAF gene 57 LDL receptor 57 aneuploidy 57 caveolin 57 homozygotes 57 #S rRNA 57 #p#.# [001] 57 gene polymorphism 57 E3 ubiquitin ligase 57 ALK gene 57 TP# mutations 57 maternally inherited 57 mutations 57 Western blotting 57 STAT1 57 pDC 57 HLA DQ2 57 ERK1 2 57 mutant allele 57 Inactivation 57 #p# [003] 57 heterozygote 57 mutated BRCA1 57 homozygous 57 splice junctions 57 leukemic cell 57 breast cancer genes BRCA1 57 ERK signaling 57 intercellular adhesion molecule 57 GPC3 57 leptin receptor 57 CYP# [002] 57 vimentin 57 gamma H2AX 57 RAR beta 57 DNA methyltransferases 57 metaplasia 57 homologous recombination 57 human leukocyte antigen HLA 57 UGT#B# 57 gene encoding 57 Li Fraumeni syndrome 57 genes predisposing 57 Pten 57 HOTAIR 56 hydroxylase 56 MDM2 56 SMN2 56 carboxyl terminal 56 transmembrane receptor 56 chromosomal regions 56 LRP5 56 KCNE2 56 miRNA expression 56 phosphatase 56 encodes protein 56 Amino acid 56 WT1 56 IgA deficiency 56 RASSF1A 56 phospholipase A2 56 TOP2A 56 mRNA transcripts 56 SMN1 gene 56 PRNP 56 splice variants 56 BRIP1 56 mutated K ras 56 H#K# [002] 56 Cytochrome 56 JAK2 enzyme 56 APOE e4 56 apolipoprotein E 56 MYBPC3 56 NFkB 56 LNCaP cells 56 virulence genes 56 DNMT1 56 KRAS oncogene 56 β catenin 56 autosomal recessive 56 CHD7 56 transgene expression 56 acid phosphatase PAP 56 inherited mutations 56 circadian genes 56 Macrophage 56 mutation 56 Microtubule 56 abnormal methylation 56 hTERT 56 mitogen activated protein kinase 56 exonuclease 56 CCR5 delta# 56 uracil 56 adenylate cyclase 56 overexpress 56 Cytogenetic 56 homodimer 56 Immunohistochemical analysis 56 familial ALS 56 fibulin 56 R#W [002] 56 rRNA genes 56 TGF β 56 Genotypes 56 chaperone proteins 56 Rho GTPases 56 gene polymorphisms 56 extracellular domain 56 NOTCH1 56 SPINK1 56 MLL2 56 nuclease 56 E#F# 56 lysosomal 56 Heterozygous 56 upregulating 56 chromosome #q# [001] 56 serine threonine kinases 56 linkage disequilibrium 56 Rb#/p# 56 indels 56 proteins encoded 56 transfected 56 #q#.# [002] 56 regulator CFTR gene 56 ETV1 56 polyamine 56 NF1 gene 55 Dysregulation 55 monocytic 55 downregulated 55 ß catenin 55 E cadherin 55 Mutational 55 p#Kip# 55 gene amplification 55 protein encoded 55 55 phosphoinositide 55 germline mutation 55 LIS1 55 transmembrane protein 55 carcinoembryonic antigen 55 1alpha 55 BRCA1 55 replicase 55 pathogenic mutations 55 tumor suppressor protein 55 transferase 55 transiently transfected 55 ERK1 55 EGFP 55 crystallin 55 55 phosphorothioate 55 Apolipoprotein E 55 hepatic lipase 55 mosaicism 55 PALB2 gene 55 colocalization 55 phosphorylate 55 missense mutation 55 FMR1 gene 55 isoenzyme 55 histological subtype 55 homozygosity 55 FLT3 55 MEF2A 55 FGFR2 55 adhesion molecule 55 RUNX3 55 lipoxygenase 55 PON1 55 FGFR1 55 VNTR 55 MMP9 55 Janus kinase 55 transmembrane 55 glycosyltransferase 55 BRAC2 55 immunoglobulin genes 55 beta globin 55 claudin 55 G6PD 55 breast carcinomas 55 CD8 + 55 Shc 55 NS3 55 cGPS ® 55 GLI1 55 mutant alleles 55 TMEM#B 55 ERalpha 55 HCT# 55 Fragile X mental retardation 55 mice lacking 55 H#K# methylation 55 cyclin dependent kinase 55 SOCS3 55 cytokine receptors 55 Supplemental Figure 55 BRCA1 gene 55 globin 55 monocyte 55 dystrophin gene 55 inactivating mutations 55 sequence homology 55 proband 55 lymph node metastasis 55 transient transfection 55 catenin 55 LRRK2 gene 55 neuroblastoma tumors 55 mitochondrial gene 55 MYH9 gene 55 amino terminal 55 KIT mutations 55 Oncogenic 55 CagA 55 OGG1 55 constitutively active 55 telomeric 55 upregulated 55 hypermethylation 55 IRE1 55 LKB1 55 upregulates 55 hypermethylated 55 Nedd4 55 alternatively spliced 55 V#E 55 orthologs 55 D. melanogaster 55 human leukocyte antigens 55 VEGF receptor 55 EGFR gene 55 uPAR 55 frameshift mutation 55 paraoxonase 55 homozygote 55 H#K#me# 55 tyrosine phosphorylation 55 dinucleotide 55 Sox2 55 NKX2 55 histone modification 55 monogenic 55 colorectal carcinoma 55 anaplastic lymphoma kinase ALK 55 short hairpin RNAs 55 RNase H 55 retinol binding protein 55 phosphoprotein 55 thrombospondin 55 IKZF1 55 chromosome #p# [001] 55 CpG island 55 RAD# [001] 54 deacetylases 54 MMP2 54 neuroligins 54 Rap1 54 TCF#L# 54 intronic 54 G#D 54 insertion deletion 54 EphB4 54 Vps# 54 CD1d 54 receptor kinase 54 kinase domain 54 constitutively 54 steroidogenic 54 serine threonine 54 alleles 54 Haplotype 54 CYP#B# 54 cytochrome b 54 alpha subunit 54 trophoblast cells 54 PTEN protein 54 TMPRSS2 ERG 54 plasminogen activator inhibitor 54 TERT 54 extracellular signal 54 secretory pathway 54 GATA4 54 genes differentially expressed 54 nucleotide sequences 54 promoter hypermethylation 54 decarboxylase 54 serine protease 54 proteolysis 54 activating mutations 54 ribonucleic acid RNA 54 coding exons 54 nucleotide excision repair 54 IDH1 gene 54 FANCD2 54 SLITRK1 54 orthologous 54 Dystrophin 54 autosomal dominant 54 uniparental 54 tropomyosin 54 APOA5 54 AMACR 54 ubiquitylation 54 tyrosine kinase 54 N acetyltransferase 54 beta actin 54 amino acid residues 54 apoE 54 induces apoptosis 54 kD 54 tyrosine kinases 54 thymidine kinase 54 BRCA1 mutation carriers 54 transduced 54 microdeletion 54 CYP#C# * 54 allele frequencies 54 somatic mutation 54 NSCLC tumors 54 Mutation Analysis 54 E3 ligase 54 kinase gene 54 CGG repeats 54 K#N 54 HLA DRB1 * 54 glutathione S transferase 54 BMAL1 54 NQO1 54 autophagic 54 VKORC1 54 LRP6 54 immunoreactive 54 single nucleotide polymorphism 54 PDGFRA 54 synthetase 54 adipogenic 54 tryptase 54 membrane proximal 54 5 lipoxygenase 54 K#R [002] 54 methylated DNA 54 Interferon gamma 54 KIF6 gene 54 rs# [003] 54 constitutive activation 54 rs# [002] 54 interleukin IL 54 rs# rs# 54 microglial 54 CYP#A# [002] 54 APOC3 54 MECP2 gene 54 c myc 54 chromosomal deletions 54 Supplementary Fig 54 HLA DR4 immune 54 paternally inherited 54 V#F mutation 54 iNOS 54 mRNAs 54 5q 54 alkaline phosphatase 54 SNP rs# [001] 54 Dpp 54 exon 54 LMNA 54 neurofibromatosis type 54 chromosome #q#.# [002] 54 APOL1 54 unmethylated 54 gag pol 54 melanocyte 54 stem cell pluripotency 54 genes BRCA 54 phosphatidylinositol 3 54 ortholog 54 ectopic expression 54 mesangial 54 polyadenylation 54 chromosomal instability 54 DQB1 * 54 metabolizing enzyme 54 GPI anchored 54 CYP#C# [001] 54 CDK4 54 Polymorphism 54 nonsense mutations 54 TNFalpha 54 KCNQ1 54 suppressor gene 54 differentially expressed genes 54 insertions deletions 54 mRNA molecules 54 nucleolar 54 spontaneous mutations 54 CYP#D# gene 54 intergenic 54 aggrecan 54 mutational analysis 54 protein CETP 54 inducible nitric oxide synthase 54 Ser# 54 TP# gene 54 micro RNA 54 FMR1 54 EGF receptors 54 Streptococcus agalactiae 54 recessive mutations 54 mRNA 54 mRNA encoding 54 GAPDH 54 ciliated 54 CXCL# 54 homeobox gene 54 SMAD4 54 metalloprotease 54 IgG antibody 54 cytochrome c oxidase 54 TIMP 1 54 ssDNA 54 budding yeast 54 UGT#A# * 54 mitochondrial enzyme 54 SOD1 protein 54 qRT PCR 54 lung adenocarcinomas 54 Leydig cell 54 receptor gene 54 p# mutation 54 autosomal dominant disorder 54 p# MAPK 54 microRNAs miRNAs 54 coactivator 54 microcephalin 54 RhoA 54 RNA polymerases 54 atypical hyperplasia 54 karyotypes 54 Cx# [001] 54 nucleotide substitutions 54 variant rs# 53 BRCA1 mutations 53 BARD1 53 regulated kinase 53 oxidase 53 Li Fraumeni 53 OCT4 53 matrix metalloproteinases MMPs 53 Cytoplasmic 53 MeCP2 gene 53 palladin 53 TTR gene 53 ERK2 53 kilobase 53 SMN protein 53 K ras mutations 53 JAK2 V#F 53 GTPase 53 Epidermal Growth Factor Receptor 53 Meckel Gruber 53 Endothelial 53 ABL1 53 survivin 53 polyomavirus 53 inherited maternally 53 huntingtin gene 53 CYP# [001] 53 β1 53 Caspase 53 cysteines 53 phosphorylated tau 53 sporadic ALS 53 CTCF 53 nucleic acid sequence 53 PAX5 53 NS1 53 downregulation 53 Saccharomyces cerevisiae 53 cytosolic 53 Tie2 53 thyroid carcinoma 53 methylation 53 chromosomal 53 microRNA expression 53 kDa protein 53 intergenic regions 53 exons 53 Germline 53 FLT3 kinase 53 Kinesin 53 heterochromatic 53 KIAA# 53 spontaneous mutation 53 Her-2/neu 53 unmutated 53 PARP inhibition 53 transactivation 53 enolase 53 mitochondrial DNA mtDNA 53 C#BL 6 mice 53 germline 53 ß lactamase 53 EGFR receptor 53 immunoblotting 53 sphingolipid 53 actinin 53 HbF 53 receptor CD# 53 Monocyte 53 surgically resected 53 receptor mediated endocytosis 53 HER2 neu 53 Akt1 53 overexpressing 53 Papillary 53 isogenic 53 CpG 53 BRCA2 gene mutation 53 homodimers 53 haplotypes 53 colorectal tumor 53 serum prostate 53 IGFBP 53 N. gonorrhoeae 53 HER2 receptor 53 BRAF mutations 53 protein kinases 53 abnormal p# 53 apolipoprotein E4 53 transcriptional coactivator 53 transmembrane proteins 53 Protein Kinase C 53 TT genotype 53 Jhdm2a 53 cytidine 53 histone H3 53 DNA methyltransferase 53 stably transfected 53 cadherin 53 BCL2 53 CD3 + 53 NF1 53 assay detects 53 neurofilament 53 haematopoietic 53 Wwox 53 MAPT 53 ORFs 53 globin genes 53 bronchoalveolar lavage fluid 53 transcriptional repressor 53 heterodimers 53 HLA B 53 thyroid carcinomas 53 homolog 53 ankyrin B 53 intrahepatic 53 valine 53 centromeric 53 allelic variants 53 BCR ABL 53 HLA loci 53 H2AX 53 cerevisiae 53 p# activation 53 TAp# 53 tumorigenicity 53 proximal tubule 53 RNase P 53 dysbindin 53 myoepithelial 53 mutant genes 53 mutated genes 53 immunoreactivity 53 gene mutations 53 breast cancer metastasis 53 ZNF# 53 endothelial activation 53 parkin gene 53 miRNA genes 53 anterior pituitary 53 nucleotide sequence 53 ApoE 53 Elevated serum 53 genes BRCA1 53 proteolytic cleavage 53 hemagglutinin H 53 glucose transporter 53 HLA DRB1 53 DGAT1 53 C1q 53 chromosomal aberrations 53 Trichophyton rubrum 53 enteroviral 53 metaphase 53 HLA B# 53 Epstein Barr virus EBV 53 HepG2 53 GenBank accession 53 mutated gene 53 Transmembrane 53 miR #a [001] 53 MDMX 53 transcriptional repression 53 immunostaining 53 HIV reverse transcriptase 53 coexpression 52 bisulfite sequencing 52 p# deficient 52 BMPR2 52 overexpression 52 μ opioid receptor 52 Cyclin D1 52 grade squamous intraepithelial 52 glycosylated 52 synovial cells 52 serine threonine kinase 52 kilobases 52 Cadherin 52 paralogs 52 intron 52 Fig. 3b 52 coding sequences 52 clusterin 52 RIP1 52 androgen receptor gene 52 autosomes 52 p# p# 52 SMN2 gene 52 isomerase 52 murine leukemia virus 52 bronchial epithelial cells 52 cytoplasmic tail 52 LPS induced 52 activating mutation 52 lactate dehydrogenase 52 Prox1 52 virulence determinants 52 transgenic rats 52 VEGFR1 52 EZH2 52 CD4 + CD8 + 52 gastric carcinomas 52 prostate carcinoma 52 replicon 52 CCL2 52 BAC clones 52 estrogen receptor alpha 52 protein tyrosine kinase 52 telomerase reverse transcriptase 52 Transcriptional 52 ESR1 52 ataxin 52 heterozygosity LOH 52 beta subunit 52 chromosome #q# [002] 52 isoprostane 52 MGMT gene 52 ductal lobular 52 nitrotyrosine 52 sFlt 1 52 adipocyte 52 precursor lesions 52 hypothalamic pituitary 52 mesotheliomas 52 glucokinase 52 monocytes macrophages 52 interferon pathway 52 β amyloid 52 ligase 52 vWF 52 Mitochondrial 52 CEACAM1 52 mitotic progression 52 polymorphisms 52 trinucleotide 52 leucine zipper 52 IGF2 52 cyclin D1 52 gastrointestinal stromal tumors GISTs 52 telomerase RNA 52 heme oxygenase 52 vesicular stomatitis virus 52 autosomal 52 nucleotide 52 paxillin 52 HER2 overexpression 52 Notch receptor 52 transcriptionally active 52 pyruvate kinase 52 urothelial carcinoma 52 Alanine 52 p# [001] 52 IDH1 52 murine model 52 PIP3 52 chemokine receptor 52 PDGFR alpha 52 threonine 52 SOD1 gene 52 miRNA 52 Drp1 52 lymphangiogenesis 52 GPC5 52 miRNAs 52 1beta 52 cytokine receptor 52 polymorphism 52 JAK2 mutation 52 gene BRCA2 52 NR#A# 52 S. cerevisiae 52 pyrimidine 52 microRNA molecules 52 TCF#L# gene 52 mtDNA 52 prolyl 52 aneuploidies 52 vacuolar 52 neurexin 52 E. faecalis 52 overexpressed 52 Peutz Jeghers syndrome 52 p# gene 52 HER2 gene 52 Rad# 52 cisplatin resistant 52 BMP signaling 52 induced phosphorylation 52 Angiotensin converting enzyme 52 insulin signaling pathways 52 Leydig cells 52 gamma globin 52 testicular germ cell 52 Epstein Barr Virus EBV 52 retinoblastoma Rb 52 Single nucleotide polymorphisms 52 H#D 52 DLX5 52 Abeta peptide 52 gp# [002] 52 ATF2 52 alpha1 52 GISTs 52 Argonaute 52 steroidogenesis 52 Solexa sequencing 52 filaggrin gene 52 regulates gene expression 52 FUS1 52 ADAMTS# 52 HER2 expression 52 CD# ligand 52 MC1R 52 Immunohistochemical staining 52 homologue 52 homologs 52 CD# expression [001] 52 potent inducer 52 amino acid substitution 52 VIPR2 52 HER2 HER2 52 uM 52 adenocarcinomas 52 eIF4E 52 acinar 52 presenilin 52 Src 52 tau protein 52 β actin 52 cytoplasmic domain 52 gene deletions 52 cytochrome oxidase 52 phosphatidylinositol 52 PDE#A 52 endoglin 52 trophoblast 52 shRNAs 52 CIN2 + 52 mediated inhibition 52 P selectin 52 glutamic acid decarboxylase 52 amino acid sequences 52 #S rRNA gene 52 Supplementary Table 52 apolipoprotein E APOE 52 aneuploid 52 UTRs 52 KLF4 52 gene MECP2 52 hydrolase 52 M#V 52 cyclin dependent kinase inhibitor 52 SCN1A 52 neoplastic 52 BubR1 52 phenotype 52 #q# deletion 52 dynamin 52 tRNA synthetase 52 gene APOE 52 eotaxin 52 Phenotypic 52 CYP#D# 52 hypomethylation 52 transcriptional regulation 51 xenograft tumors 51 CFTR cystic fibrosis transmembrane 51 RNA extraction 51 beta1 integrin 51 GPx 51 proteoglycan 51 carboxy terminal 51 gene 51 microsatellite markers 51 covalently bound 51 thymidylate synthase TS 51 gene encodes 51 micro RNAs 51 Human Leukocyte Antigen 51 heme oxygenase 1 51 SHANK3 51 major histocompatibility complex 51 molecular scissors 51 hyper IgE syndrome 51 monozygotic twins 51 DICER1 gene 51 fig. S8 51 C#T [002] 51 thyroid hormone receptor 51 miR #a [002] 51 alanine 51 SNCA 51 Apolipoprotein 51 Cathepsin B 51 ß1 51 FasL 51 thioredoxin 51 amplicons 51 Arp2 3 51 adherens junctions 51 RFLP 51 51 telomere dysfunction 51 syntaxin 51 transcriptional regulator 51 subcellular compartments 51 protein tyrosine phosphatase 51 lacZ 51 cytoplasmic 51 Frizzled 51 proteolytic processing 51 MEFs 51 #S rDNA 51 IDH2 51 miRNAs miR 51 enzymatic activity 51 apoE4

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