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(Click for frequent words.) 67 homodimers 67 constitutively 67 KIAA# 67 heterodimers 66 Polycomb 66 MT1 MMP 66 cytoplasmic domain 66 serine protease 66 cdk5 66 PcG 66 sequence homology 66 constitutively expressed 65 proteins encoded 65 CagA 65 transcriptional repressor 65 subcellular localization 65 lysine residues 65 oligomerization 65 H#K# [002] 65 JAK STAT 65 metabolizing enzymes 65 histone H4 65 deacetylation 65 proline rich 65 actin binding 65 intronic 65 FOXO3a 65 Histone 64 synthetase 64 phosphorylates 64 kDa protein 64 4E BP1 64 genes encoding 64 #S rRNA 64 paxillin 64 HepG2 cells 64 evolutionarily conserved 64 sphingolipid 64 metabolic enzymes 64 Rab5 64 PKC isoforms 64 Ago2 64 tropomyosin 64 nucleolar 64 plastid 64 methylated DNA 64 ß catenin 64 amine oxidase 64 PDZ domain 64 glycosyltransferase 64 downregulated 64 KLF4 64 rRNA 64 TAp# 64 plastids 64 beta actin 64 subcellular compartments 64 glycosylated 64 mammalian tissues 64 tetramer 64 uPAR 64 SUMOylation 64 fission yeast 64 ubiquitylation 63 alpha subunit 63 substrate specificity 63 defensin 63 catenin 63 transcriptional activation 63 protein fragment 63 neuroligins 63 furin 63 receptor ligand 63 coreceptor 63 acetylcholine receptor 63 SVZ 63 FGF2 63 ras gene 63 H#K#me# 63 chloroplast 63 ubiquitin ligase 63 Immunohistochemical analysis 63 anterior pituitary 63 IKKß 63 non coding RNA 63 centromeric 63 kinase domain 63 AMACR 63 Nedd4 63 constitutively active 63 Cytochrome 63 protein tyrosine phosphatase 63 polyamine 63 dimeric 63 orthologous 63 tRNA synthetase 63 At#g# 63 transiently transfected 63 null mice 63 colocalization 63 MAPK 63 mRNA transcripts 63 p#NTR 63 phospholipase 63 NR2B subunit 63 retinoid X 63 dioxygenase 63 Alu elements 63 metabolizing enzyme 63 Rap1 63 nAChR 63 transcriptional regulation 63 protein encoded 63 CD1d 63 CYP#B# 63 MAP kinase 63 BMP4 62 PrPSc 62 oligomeric 62 orthologs 62 ribosomal protein 62 serine threonine kinase 62 mucins 62 LDL receptor 62 chromatin structure 62 piRNAs 62 PTPN# 62 perivascular 62 peroxidase 62 TRAF6 62 Sp1 62 cytochrome 62 coactivator 62 PPARg 62 mitogen activated protein kinase 62 inhibin B 62 F actin 62 hydrolase 62 cell adhesion molecule 62 acetyltransferase 62 phosphatase 62 unmethylated 62 transcriptionally active 62 cytoplasmic 62 missense mutations 62 cathepsins 62 synthases 62 esterase 62 adenylate cyclase 62 ESR1 62 NFAT 62 enolase 62 receptor tyrosine kinase 62 DLC1 62 RhoA 62 transduced 62 proteinase 62 lipid rafts 62 RNA binding 62 ERK signaling 62 centromeres 62 mRNA expression 62 adduct 62 Kir#.# 62 synthase 62 p#/CBP 62 IgG1 62 Vps# 62 myo inositol 62 aminopeptidase 62 demethylase 62 kinase gene 62 polypeptide 62 Notch receptor 62 MDR1 62 endonuclease 62 kinesin motor 62 fig. S4 62 coexpression 62 ubiquitination 62 methyltransferases 62 pDCs 62 splice variants 62 TRPV3 62 carboxyl terminal 62 LRP6 62 NKX#.# 62 odorant receptor 62 circadian clock genes 62 hippocampal neurons 62 mutant allele 62 MALAT1 62 transcriptional coactivator 62 apoE 62 SIRT2 62 alternatively spliced 62 proteolytic 61 overexpressing 61 disulfide bond 61 RNA polymerases 61 dehydrogenase 61 guanosine 61 Upregulation 61 ERK1 61 DARPP 61 DNMT1 61 histone H3 61 receptor gamma 61 potent inhibitors 61 glutamine synthetase 61 virulence genes 61 homodimer 61 insulin signaling pathway 61 monomeric 61 beta subunit 61 ribonuclease 61 presenilin 61 COL#A# 61 A. thaliana 61 β1 61 immunoreactivity 61 Proteobacteria 61 amino terminal 61 methylation patterns 61 cathepsin B 61 RNA transcripts 61 nucleolin 61 N. benthamiana 61 Clusterin 61 phagocyte 61 syntaxin 61 ERK1 2 61 CXCL# 61 caveolae 61 calpain 61 miR# 61 glutamate receptors 61 metalloprotease 61 ploidy 61 proto oncogene 61 histone acetyltransferase 61 c Myb 61 peroxisomal 61 EphB4 61 osteoblast 61 regulated kinase ERK 61 HOTAIR 61 lymphoid cells 61 H#K# [001] 61 cDNAs 61 transcriptional silencing 61 vacuolar 61 glycolipid 61 ERBB2 61 lysates 61 acetyl CoA 61 posttranslational modifications 61 Sox9 61 proapoptotic 61 Xenopus laevis 61 HipA 61 Leydig cells 61 GABAB receptors 61 transferrin receptor 61 exonuclease 61 Hh 61 prolyl 61 Cathepsin B 61 phosphoinositide 61 heterochromatic 61 recombinase 61 major histocompatibility complex 61 epigenetically 61 amino acid substitutions 61 miRNA expression 61 FUS1 61 TrkB 61 postsynaptic 61 centrosome 61 importin 61 untranslated regions 61 cytopathic 61 pRb 61 coactivators 61 5 hydroxymethylcytosine 61 glucocorticoid receptor 61 GLUT4 61 splenocytes 61 autoreactive 61 GPx 61 degrading enzymes 61 adhesion molecule 61 cell adhesion molecules 61 translationally 61 CD#b 61 morphogen 61 oxidases 61 DNA methyltransferases 61 WNK1 61 IFN g 61 astrocytic 61 transcriptional regulators 61 constitutive expression 61 beta1 integrin 61 homeobox gene 61 homologues 61 E3 ligase 61 biosynthetic pathway 61 GTPase 61 polyamines 61 thioredoxin 61 short hairpin RNAs 61 E1A 61 acid phosphatase 61 PKD1 61 phosphoprotein 61 carboxylic acid 61 phosphorylated 61 HDAC2 61 1alpha 61 tumorigenicity 61 TGF ß 61 AMPA receptor 61 Androgen receptor 60 glycolipids 60 EGFP 60 p# MAPK 60 lacZ 60 diffusible 60 alpha secretase 60 histone modifications 60 Prox1 60 cultured neurons 60 synuclein 60 isoleucine 60 FGFs 60 quinone 60 exocytosis 60 p#Kip# 60 isotypes 60 cytochrome b 60 Phosphorylation 60 DRD2 60 tetramers 60 hexose 60 peptidoglycan 60 TCF#L# 60 presynaptic 60 prostaglandin E2 PGE2 60 SNP rs# [001] 60 nitrogenase 60 sphingomyelin 60 enterocytes 60 operon 60 Jurkat cells 60 polyploid 60 IGF1R 60 activin 60 Fig. 1A 60 Dopaminergic 60 cysteine residues 60 proteases 60 tyrosine phosphorylation 60 receptor molecule 60 vasopressin receptor 60 caveolin 60 isozymes 60 uracil 60 CCL# 60 BALB c mice 60 membrane proximal 60 cyclic AMP cAMP 60 unicellular organism 60 ABCB1 gene 60 ZNF# 60 HER2 HER3 60 T#M 60 phosphatases 60 keratins 60 kappa opioid receptor 60 oncogenic 60 microglial 60 budding yeast 60 promoter methylation 60 MAPK pathway 60 evolutionary conserved 60 heterozygotes 60 differential gene expression 60 paralogs 60 STAT1 60 primary cilia 60 CYP#E# 60 site directed mutagenesis 60 gamma aminobutyric acid 60 MMP# 60 immunostaining 60 GAPDH 60 cyclin dependent kinase inhibitor 60 oxidative enzymes 60 ribonucleotide 60 matrix metalloproteinase 60 synaptogenesis 60 acyl CoA 60 CTCF 60 focal adhesion kinase FAK 60 transgenic mice expressing 60 mitotic progression 60 MLL gene 60 heterochromatin 60 oncoprotein 60 aromatase 60 Foxp3 60 pyramidal neurons 60 ligases 60 ribonucleoprotein 60 hypermethylated 60 kinase enzymes 60 ortholog 60 isoforms 60 lipoxygenase 60 EF Tu 60 phosphorylate 60 glycoproteins 60 secretory 60 proteolytic cleavage 60 transmembrane receptor 60 Notch1 60 microsatellite markers 60 ubiquitinated 60 neurite outgrowth 60 FKBP# 60 neurofilament 60 D aspartic acid 60 CYP#A# [002] 60 1beta 60 forkhead 60 β 60 palmitoylation 60 hapten 60 hydrolases 60 PGC 1α 60 GPI anchored 60 MAPKs 60 ciliated 60 cypin 60 MnSOD 60 H2AX 60 androgen receptor AR 60 5' triphosphate 60 JAK2 enzyme 60 cytokine receptor 60 phytochrome 60 BubR1 60 downregulate 60 deacetylase 60 serine threonine 60 olfactory receptor 60 melanocyte 60 eukaryotic cell 60 HERV 60 autophagic 60 stromal cells 60 cyclophilin D 60 FGFR2 60 RAD# [001] 60 plasminogen activator 60 EBNA1 60 kD 60 TGF beta1 60 Monocytes 60 extracellular domain 60 dimerization 60 secretase 60 ncRNAs 60 GluR1 60 mosaicism 60 USP# 60 vascular endothelial cells 60 tyrosine kinase receptor 60 HSF1 60 BMP signaling 60 gene encodes protein 60 dehydrogenases 60 PDGFR 60 receptor gene 60 chemokine receptor 60 nicotinic receptor 60 lincRNA 60 SOD1 60 PKM2 60 transmembrane domains 60 VEGFR1 60 FGFR4 60 ribosomal proteins 60 Fig. 2a 60 secreted protein 60 SMN1 60 histidine 60 outer membrane proteins 60 gene encodes 60 cytosolic 60 Jhdm2a 60 subventricular zone 59 fascin 59 SGK1 59 CaM 59 immunodominant 59 Western blotting 59 intermediate filaments 59 intestinal epithelial cells 59 glutamate receptor 59 mitochondrial gene 59 globin genes 59 ERalpha 59 histone modification 59 Arabidopsis 59 mitogen activated protein kinases 59 cyclic adenosine monophosphate cAMP 59 steroidogenic 59 RANTES 59 striatal 59 CPEB 59 perilipin 59 tumor suppressor protein 59 oligosaccharide 59 Purkinje cell 59 DNA methyltransferase 59 NKCC1 59 Microtubule 59 Argonaute 59 ATPase 59 enzymatic pathway 59 metalloproteinase 59 IgG4 59 TEL AML1 59 CHD7 59 p# mutation 59 FGFR1 59 interleukins 59 PGCs 59 lyase 59 immunofluorescence microscopy 59 spermatogonia 59 thiol 59 Phenylalanine 59 capsid protein 59 TRP channels 59 MyD# 59 Mice deficient 59 aggrecan 59 beta. 59 MMP9 59 phosphatidylinositol 3 59 noncoding RNAs 59 proline 59 serotonin transporters 59 upregulates 59 β actin 59 PAK1 59 centrioles 59 cysteines 59 GLI1 59 Protein Kinase C 59 GPR# [002] 59 nucleotide sequences 59 PPARγ 59 PDZ domains 59 RNase L 59 proteinases 59 CD# ligand 59 membrane protein 59 Kupffer cells 59 neural progenitor cells 59 chemoattractant 59 E3 ubiquitin ligase 59 serotonin transporter 59 chitinase 59 Nanog 59 effector molecules 59 microRNA expression 59 soluble fms 59 actin polymerization 59 VEGF receptor 59 phosphatidylinositol 59 Drosophila embryos 59 PAX5 59 vimentin 59 endogenous ligand 59 pyruvate kinase 59 somatostatin 59 flavin 59 eukaryotic 59 STIM1 59 NFκB 59 Cdc# 59 Secretase 59 homologs 59 Fas ligand 59 heparan sulfate 59 μ opioid receptor 59 BMAL1 59 Vpr 59 γ 59 PTP1B 59 PGC1 59 synaptotagmin 59 palmitate 59 HBx 59 ErbB4 59 aspartate 59 erythrocytes 59 plant Arabidopsis thaliana 59 glyceraldehyde 3 59 C EBP alpha 59 fig. S1 59 hnRNP 59 Wwox 59 transmembrane 59 insulin signaling pathways 59 acyltransferase 59 regulates gene expression 59 SOX9 59 protein isoforms 59 PLA2 59 CD#c 59 RRM1 59 LIS1 59 transcriptionally 59 estrogen receptor alpha 59 TEP1 59 XPB 59 vitamin D receptors 59 ADAM# 59 Cx# [001] 59 aberrantly activated 59 fig. S# 59 tyrosine residues 59 COOH terminal 59 MiRNAs 59 DNA demethylation 59 aryl hydrocarbon receptor 59 MDSCs 59 cerevisiae 59 cofilin 59 effector protein 59 intracellular bacteria 59 mammary stem cells 59 Caenorhabditis elegans 59 Rho GTPases 59 GFP fusion 59 hematopoietic progenitor cells 59 enzymatic activity 59 bilayers 59 C#Y 59 cadherin 59 germline mutations 59 oligomers 59 differentially regulated 59 protein subunits 59 acylated 59 cells transfected 59 Smad4 59 serum antibodies 59 operons 59 JNK1 59 Aromatase 59 TERT 59 CXCR2 59 apical membrane 59 TRPV4 59 cyclin E 59 mitochondrial enzyme 59 transactivation 59 tyrosine phosphatase 59 TIMP 59 cultured rat 59 costimulatory 59 soluble proteins 59 PON1 59 Butyrate 59 stably transfected 59 unmethylated DNA 59 HLA DQ2 59 PIP2 59 adipokines 59 phospho 59 UCP1 59 RNA silencing 59 histone 59 EphA2 59 endocytic 59 Or#b 59 Cytoplasmic 59 thymocytes 59 meiotic recombination 59 ssDNA 59 neuronal stem cells 59 reductase 59 miRNA genes 59 microRNAs miRNAs 59 retrotransposon 59 carboxy terminal 59 thrombospondin 59 protein tyrosine kinase 59 p# mitogen activated 59 upregulate 59 cytokine receptors 59 PIP3 59 mitochondrial enzymes 59 ribosomal DNA 59 antiproliferative activity 59 phosphorylated proteins 59 nAChRs 59 59 SMAD4 59 glycosylated proteins 59 ribonucleic acids 59 heterozygote 59 secretory pathway 59 Metabolites 59 MC1R 59 RAR beta 59 condensin 59 superoxide dismutase 59 hydroxylase 59 Pax6 59 immunoreactive 59 dystroglycan 59 transmembrane proteins 59 cardiac fibroblasts 59 endospores 59 histone methylation 59 thyrotropin 59 Pol IV 59 HDACs 59 mouse testes 59 matrix metalloproteinases MMPs 59 transferase 59 eotaxin 59 SAP# 59 previously uncharacterized 59 centromere 59 chromatin remodeling complex 59 NKG2D 58 transcriptional regulator 58 Kv#.# 58 palladin 58 acetylated 58 lysosomal 58 extracellular domains 58 neuromuscular junction 58 quantitative trait loci 58 biogenesis 58 amino acid residues 58 eIF4E 58 lysophosphatidic acid 58 NF1 gene 58 Syt II 58 protein kinase C 58 SOCS3 58 torsinA 58 amino acid alanine 58 mutant proteins 58 luciferase reporter 58 C#BL 6 58 inflammatory cytokine 58 myosin VI 58 ectopic expression 58 micro RNAs 58 immunoblotting 58 tyrosine hydroxylase 58 GABAergic 58 neuropeptides 58 mRNA molecules 58 Notch signaling 58 APOBEC3G 58 spectrin 58 olfactory receptor neurons 58 GnRH neurons 58 PTEN gene 58 MDCK cells 58 synapse formation 58 estrogen metabolism 58 SCD1 58 hTERT 58 eNOS 58 GRP# 58 supernatants 58 beta amyloid peptide 58 ligand binding domain 58 S. cerevisiae 58 cAMP signaling 58 Ca2 + 58 interleukin 1ß 58 cysteine protease 58 morphogens 58 chloroplast genome 58 glutathione S transferase 58 MAP kinases 58 dysbindin 58 TLE3 58 methyltransferase 58 ALDH2 58 carboxylate 58 prodynorphin 58 protein p# 58 paraventricular nucleus 58 plasmacytoid dendritic cells 58 carboxyl 58 protein phosphatase 58 Cytotoxic T 58 upregulation 58 FGFR3 58 actin cytoskeleton 58 hydroperoxide 58 GSK3B 58 C1q 58 oligodendroglial progenitor cells 58 CEACAM1 58 tenascin C 58 inherited maternally 58 p# mutations 58 suppressor gene 58 Id1 58 hypervariable 58 transmembrane protein 58 iNOS 58 DDB1 58 trophoblast cells 58 LNCaP 58 N acetyltransferase 58 LNCaP cells 58 interneurons 58 antimicrobial peptide 58 bispecific 58 intracellular signaling 58 transgene expression 58 Synthase 58 focal adhesion 58 fibronectin 58 cytidine 58 beta globin 58 #β HSD1 58 opioid peptides 58 HER2 receptor 58 DNA adducts 58 equimolar 58 extracellular signal 58 FGF signaling 58 protein kinases 58 Sonic Hedgehog 58 adrenal cortex 58 Hypoxia Inducible Factor 58 c Src 58 diphosphate 58 adrenoceptor 58 histone deacetylases HDACs 58 overexpressing cells 58 upregulated 58 PrPC 58 isogenic 58 micronuclei 58 Prolactin 58 unconjugated 58 genetic loci 58 endogenous ligands 58 druggable target 58 nitric oxide synthase 58 C#BL 6 mice 58 alpha2 58 intracellular Ca 2 58 trimeric 58 acinar 58 redox active 58 cyclic nucleotide 58 IL 1beta 58 cyclooxygenase COX 58 6S RNA 58 trypanosome 58 ENaC 58 Tie2 58 ERa 58 catalase 58 Arf gene 58 receptor subunit 58 trophoblast 58 phagocytic cells 58 ERK2 58 cytochromes 58 NS3 58 M1 muscarinic 58 Wnts 58 Fig. 2C 58 noncoding 58 acetylcholine receptors 58 gene locus 58 sGC 58 superfamily 58 p# activation 58 human mammary epithelial 58 Hsp# [001] 58 Oncogenic 58 GNAQ 58 topoisomerases 58 histone methyltransferase 58 isoenzyme 58 isoenzymes 58 posttranslational modification 58 ERK pathway 58 synaptic vesicle 58 synaptic vesicles 58 chromatin proteins 58 glycosylation 58 microRNA molecules 58 HEK# cells 58 Auxin 58 E#F# 58 globin gene 58 mediated inhibition 58 mammaglobin 58 molecule binds 58 cis regulatory 58 chick embryos 58 ALDH 58 IRE1 58 excitatory synapses 58 #β estradiol 58 Drosha 58 polymerases 58 copper zinc superoxide 58 glomerular 58 Src kinase 58 CCR7 58 telomerase RNA 58 AhR 58 replicase 58 OCT4 58 adipocyte differentiation 58 VE cadherin 58 oligodendrocyte 58 methyl groups 58 PALB2 58 BMP2 58 transcriptomes 58 chromosome #q# [002] 58 glutamate transporter 58 oxidative phosphorylation 58 ribosomal genes 58 replicon 58 keratinocyte 58 TMEM#B 58 hippocampal cells 58 coiled coil 58 #S proteasome 58 spermidine 58 IFN gamma 58 HIF 1alpha 58 MTHFR 58 transduce 58 TSP1 58 GFP fluorescence 58 telomeric 58 ribosomal RNA rRNA 58 miR #a [001] 58 pulvinar 58 Fig. 1C 58 MyoD 58 transporter proteins 58 MMP2 58 preferentially bind 58 desaturase 58 #ß 58 GABA receptor 58 reinhardtii 58 histone acetylation 58 tumor suppressive 58 glutamatergic 58 T lymphocyte 58 intracellularly 58 S. pombe 58 glycan binding 58 multiprotein complex 58 glycogen synthase 58 nuclease 58 nucleic acid molecules 58 tyrosine 58 mammalian sperm 58 Arabidopsis genome 58 TSLP 58 #BP# 58 oxysterols 58 mutant huntingtin protein 58 enzymatically active 58 cytokeratin 58 sialic acids 58 polyadenylation 58 maternally inherited 58 moieties 58 Klf4