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(Click for frequent words.) 75 tumorigenicity 74 constitutively expressed 74 ERCC1 74 TIMP 1 73 subcellular localization 73 GSTP1 73 splice variants 73 Immunohistochemical staining 73 thymidylate synthase TS 73 HepG2 cells 73 mediated inhibition 73 immunohistochemical analysis 73 Western blotting 73 cell adhesion molecule 73 mRNA expression 73 Clusterin 73 ERK1 2 72 prostate carcinoma 72 siRNA knockdown 72 carcinoembryonic antigen 72 P2X 72 Immunohistochemical analysis 72 Upregulation 72 immunostaining 72 AMACR 72 ERBB2 72 promoter methylation 72 hypermethylated 72 MDR1 72 antiproliferative activity 72 mRNA transcripts 72 mutated K ras 72 ZNF# 72 BRAF V#E 71 Cathepsin B 71 TGF alpha 71 immunohistochemical 71 Microarray analysis 71 ABCB1 71 syngeneic 71 FGFR3 71 K ras mutations 71 NKX#.# 71 c MYC 71 AGTR1 71 BCL2 71 gene polymorphisms 71 DNA methyltransferases 71 colon carcinoma 71 lactate dehydrogenase LDH 71 ERK signaling 71 immunoblotting 71 EGFR HER2 71 HER2 neu 71 adipogenic 71 β1 71 E#F# 71 TNFalpha 71 ERalpha 71 HER2 expression 71 PTPN# 71 P cadherin 71 lymphangiogenesis 71 HIF 1alpha 71 HER2 HER2 71 methylation patterns 71 CEACAM1 70 rs# [004] 70 NSCLC tumors 70 protein tyrosine phosphatase 1B 70 MLH1 70 p#NTR 70 cisplatin resistant 70 PCA3 gene 70 IGFBP2 70 HIF 1a 70 monocytes macrophages 70 beta actin 70 antiapoptotic 70 pancreatic endocrine 70 vimentin 70 lactate dehydrogenase 70 bronchial epithelial cells 70 TTR gene 70 gastric adenocarcinoma 70 bFGF 70 poly ADP ribose polymerase 70 upregulates 70 miRNA expression 70 transthyretin 70 qRT PCR 70 Leydig cells 70 interleukin IL -# 70 FUS1 70 colorectal adenocarcinoma 70 p#Kip# 70 sequence homology 70 pathophysiological effects 70 microglial 70 TRAIL R2 70 thyrotropin 70 androgen receptor AR 70 proapoptotic 70 PDGFR 69 DEAR1 69 PHD2 69 Ki# 69 mitogen activated protein kinases 69 serine threonine 69 pDC 69 gastric carcinomas 69 histone acetylation 69 hepatocyte 69 neurite outgrowth 69 potently inhibited 69 S#A# [002] 69 #T# L1 69 caveolin 1 69 colorectal carcinoma 69 bronchoalveolar lavage fluid 69 homodimers 69 p# INK4a 69 matrix metalloproteinases 69 ERK pathway 69 heparanase 69 p# MAPK 69 beta1 integrin 69 protein tyrosine phosphatase 69 Dysregulation 69 matrix metalloproteases 69 SMAD4 69 Protein Kinase C 69 ESR1 69 isoenzyme 69 M1 muscarinic 69 flavopiridol 69 miR #a [001] 69 GRP# 69 hepatoma 69 Cytotoxic T 69 deacetylation 69 CD# CD# 69 metalloproteinase 69 RAR beta 69 ultrastructural 69 COL#A# 69 hypomethylation 69 PDGF B 69 HOXB# 69 somatostatin 69 PC3 cells 69 TGF beta1 69 papillary renal cell carcinoma 69 cytokeratin 69 gene polymorphism 69 downregulated 69 MMP9 69 transgene expression 69 HER2 overexpression 69 MTT assay 69 TMPRSS2 ERG 69 circadian genes 69 proto oncogene 69 trophoblast cells 69 Jhdm2a 69 differentially expressed genes 69 FLT3 69 5alpha reductase 69 uPAR 69 mitogen activated protein kinase 69 Akt activation 69 PIK3CA 69 redox active 69 p# p# 69 tryptase 69 effector function 69 CD# expression [001] 69 T#M 69 mutated p# 69 gefitinib Iressa 69 FGFR2 69 immunohistochemical staining 69 Tie2 69 5 HT2A serotonin 69 differential gene expression 69 CXCR4 expression 69 antisense inhibition 69 XL# inhibits 69 pro angiogenic 68 SNP rs# [001] 68 constitutively active 68 PTHrP 68 MAP kinase 68 monocytic 68 Histone 68 p# activation 68 inhibin B 68 MMP# 68 serine threonine kinase 68 TIMP 68 WT1 68 NKG2D 68 miRs 68 p# biomarker 68 Leydig cell 68 CYT# potent vascular disrupting 68 MSH2 68 Histologic 68 metabolomic profiles 68 glutathione S transferase 68 peripheral blood mononuclear 68 Polymorphisms 68 PDGF receptor 68 LRP6 68 ADAMTS# 68 antiproliferative effects 68 lymph node metastasis 68 Fibroblast 68 constitutively activated 68 GLUT4 68 VEGF receptor 68 metabolizing enzyme 68 SSc 68 rs# [001] 68 steroidogenic 68 aurora kinase 68 KRAS oncogene 68 cyclin dependent kinase inhibitor 68 Fas ligand 68 interferon γ 68 CDKN2A 68 HCV replicon 68 synovial tissue 68 ABL1 68 transiently transfected 68 Angiotensin converting enzyme 68 MCF7 cells 68 receptor inhibitor 68 posttranslational modifications 68 TOP2A 68 uricase 68 activin 68 ß catenin 68 substrate specificity 68 GLUT1 68 CpG island 68 orthologs 68 cytotoxicity assays 68 potent suppressor 68 cyclin E 68 mutational status 68 microsatellite instability 68 HIF 1α 68 LNCaP cells 68 Oncogenic 68 microsomal 68 GLI1 68 IGF IR 68 HepG2 68 c fos 68 induces apoptosis 68 Mutational 68 p# Shc 68 somatic mutations 68 FKBP# 68 clinicopathological 68 annexin 68 prostate epithelial cells 68 intercellular adhesion molecule 68 coexpression 68 downregulates 68 HLA DR 68 #S rRNA 68 Fc receptor 68 nutlin 3a 68 MT1 MMP 68 heterozygotes 68 ectopic expression 68 GPI anchored 68 inducible nitric oxide synthase 68 HER2 amplification 68 receptor tyrosine kinase 68 serine protease 68 transferase 68 gene amplification 68 promoter hypermethylation 68 MMP2 68 #ß 68 methylenetetrahydrofolate reductase 68 alkaline phosphatase ALP 68 haematopoietic 67 CYP#A# [002] 67 tyrosine phosphorylation 67 DNA methylation patterns 67 PC# cells 67 clonogenic 67 PARP1 67 cAMP signaling 67 acinar 67 ribosomal protein 67 Cytochrome P# 67 IFN g 67 EGFP 67 eIF4E 67 TLE3 67 annexin V 67 paxillin 67 microvessel density 67 CagA 67 wildtype 67 CDK4 67 endoglin 67 Activating mutations 67 selectively inhibited 67 LPS induced 67 OCT4 67 siRNAs targeting 67 Caveolin 1 67 colorectal tumor 67 intact parathyroid hormone 67 Immunohistochemical 67 H#K#me# 67 Rb#/p# 67 DNMT1 67 TRAIL induced apoptosis 67 demonstrated antitumor activity 67 alveolar epithelial cells 67 osteoblast 67 novel VDA molecule 67 CD#b 67 chondrocyte 67 neural progenitor 67 LRP5 67 IFN γ 67 Phosphorylation 67 gene expression microarrays 67 IL 1ß 67 Xenograft 67 quantitative RT PCR 67 aminotransferase 67 RNA polymerases 67 microRNA expression 67 #S rRNA gene 67 IL #p# 67 lymphoid cells 67 hydrolase 67 Rap1 67 pRb 67 isotypes 67 VSV G 67 glutamic acid decarboxylase 67 immunoreactivity 67 hTERT 67 selective modulator 67 fruitfly Drosophila 67 Eg5 67 iNOS 67 intermediate filaments 67 E selectin 67 HLA DQ2 67 RAS RAF MEK 67 caveolin 67 HAAH 67 clinicopathological features 67 Aromatase 67 BMP2 67 c myc 67 breast carcinomas 67 ptau 67 Sertoli cell 67 Î ² 67 pharmacodynamic markers 67 potently inhibit 67 CIN2 + 67 EGF receptors 67 lymphomas leukemias 67 HDAC enzymes 67 histologic subtype 67 transgenic mouse model 67 colocalization 67 4E BP1 67 BRAF V#E mutation 67 neovasculature 67 NOD SCID mice 67 transduced 67 induced apoptosis 67 androgen dependent 67 TPMT 67 myo inositol 67 cytokine receptor 67 Introgen ADVEXIN 67 immunocytochemistry 67 estrogen receptor alpha 67 HER2 HER3 67 intronic 67 malignant prostate 67 tumor infiltrating lymphocytes 67 SNP rs# [002] 67 lesional 67 orthologous 67 vascular endothelial 67 Histological 67 epithelia 67 IL #R 67 FGFR4 67 monogenic 67 acyltransferase 67 STK# [002] 67 GHRH 67 Flt3 67 murine model 67 apoE 67 proteoglycan 67 Elevated serum 67 GPC3 67 genes encoding 67 SLC#A# [002] 67 LHRH receptor positive 67 osteoprotegerin 67 HCT# 67 ErbB1 67 transgenic mouse models 67 situ hybridisation 67 kidney allograft 67 umbilical vein 67 retinoic acid receptor 67 fosbretabulin 67 ultrastructure 67 HEK# cells 67 radiosensitivity 67 functional polymorphism 67 anti CD3 67 mRNA encoding 67 unresectable tumors 67 Cx# [001] 67 HER2 ErbB2 67 selective inhibition 67 FGF2 67 HepDirect prodrug 67 enolase 67 muscarinic receptor 67 tumor antigen 67 transgenic rats 67 adrenocortical 66 SOX9 66 aT cell 66 aggrecan 66 LRAT 66 Lp PLA 2 66 rs# [002] 66 epithelial tumors 66 EGFR receptor 66 supernatants 66 MAPK pathway 66 overactivation 66 kidney urologic 66 oxidases 66 breast cancer subtypes 66 EGFR mutant 66 vitro cytotoxicity 66 ligand induced 66 Epidermal Growth Factor Receptor 66 motoneurons 66 phosphorylates 66 gene rearrangements 66 eNOS 66 EGFR protein 66 stably transfected 66 synovial cells 66 Modulates 66 hypoxia inducible factor 66 mutational analysis 66 inactivating mutations 66 adenylate cyclase 66 Overexpression 66 KRAS mutation 66 prostate cancer CaP 66 methyltransferase 66 c KIT 66 dose proportionality 66 ankyrin repeat 66 hydroxylase 66 heterodimers 66 astrocytic 66 thyroid carcinoma 66 interleukin IL -6 66 virulence genes 66 NFKBIA 66 somatostatin receptors 66 Smad3 66 mucinous 66 Nedd4 66 mda 7 66 PKC delta 66 PGC 1α 66 nodal metastasis 66 telomerase inhibition 66 mononuclear 66 TET2 66 flow cytometric 66 tumor necrosis 66 Drosha 66 NF kappaB activation 66 oncogenic mutations 66 osteogenic 66 CD#c 66 P selectin 66 paralogs 66 gastrointestinal stromal tumors GISTs 66 prognostic markers 66 drug metabolizing enzymes 66 Factor Receptor 66 decarboxylase 66 urate oxidase 66 TGF ß 66 dinucleotide 66 MAPK 66 cytokines chemokines 66 GPx 66 receptor kinase 66 TOP2A gene 66 N cadherin 66 V#F mutation 66 #beta HSD1 66 clusterin 66 monocyte chemotactic protein 66 tumor xenograft models 66 ovarian pancreatic 66 murine models 66 HER3 66 regulated kinase ERK 66 thyroglobulin 66 transmembrane receptor 66 Adrenergic 66 CDK inhibitor 66 DU# [002] 66 transcriptional regulator 66 cMET 66 RT qPCR 66 γ secretase 66 pancreatic ductal 66 serum biomarkers 66 gastric carcinoma 66 gp# protein [002] 66 renal fibrosis 66 metalloprotease 66 splice variant 66 transmembrane protein 66 HER2 receptor 66 integrin expression 66 1beta 66 lysine residues 66 autophagic 66 transcriptional regulation 66 A3 adenosine receptor 66 antisense inhibitors 66 Tg mice 66 microtubule associated 66 T#I [002] 66 Androgen receptor 66 catenin 66 EphB4 66 #β HSD1 66 Leukemias 66 Epstein Barr Virus EBV 66 chemosensitivity 66 F FLT 66 urothelial carcinoma 66 retinoid X 66 elastase 66 JNK1 66 potent inducer 66 glutamine synthetase 66 mitogenic 66 FasL 66 miR #a [002] 66 VKORC1 66 mTOR mammalian target 66 PI3K AKT 66 Rab5 66 transcriptional activation 66 DNA methyltransferase 66 TMPRSS2 ERG fusion 66 Cyclin E 66 cells overexpressing 66 ERa 66 RAF kinase VEGFR 66 mediated apoptosis 66 immunoreactive 66 GATA3 66 ETV1 66 surgically resected 66 Endometrial 66 B7 H3 66 anaplastic lymphoma kinase ALK 66 C#Y 66 isoprostane 66 cytochrome P 66 kDa protein 66 oncogenic transformation 66 antiangiogenic activity 66 evolutionarily conserved 66 lung epithelial cells 66 histological subtype 66 phosphoprotein 66 CDH1 66 DLC1 66 Hepatocytes 66 Macrophage 66 lipoxygenase 66 VEGFR1 66 TRPV4 66 SPINK1 66 renal cysts 66 Estrogen Receptor 66 proteomic analysis 66 TGF ß1 66 CHD7 66 tumor xenografts 66 thyroid peroxidase 66 tests miRview TM 66 UGT#A# 66 urothelial 66 TNF α 66 upregulating 66 leukocyte counts 66 NS3 66 CD# ligand 66 Secretase 66 polyamine 66 cytosolic 66 proteins encoded 66 transcriptional profiles 66 PPARgamma 66 immunofluorescence microscopy 66 experimentally validated 66 mutant allele 66 phosphoinositide 66 c Myb 66 cyclin dependent kinase 66 AT1R 66 Annexin V 66 HLA DR4 66 c myb 66 Akt phosphorylation 66 MEK ERK 66 Extracellular 66 hypothalamic pituitary 66 Tasigna prolongs 66 myeloperoxidase 66 multivariate Cox 66 SETDB1 66 colony stimulating factor 66 ^ sup #m 65 p#INK#a 65 bronchoalveolar lavage 65 IgG1 65 K RAS 65 p# mutation 65 metaplasia 65 histone deacetylases 65 Monocyte 65 human chorionic gonadotropin hCG 65 potent inhibition 65 TNFa 65 Cystatin C 65 SOCS3 65 hnRNP 65 anterior pituitary 65 antibody mediated 65 hematological relapse 65 succinate dehydrogenase 65 Pharmacodynamic 65 potent inhibitors 65 BCR ABL1 65 CD1d 65 p tau 65 STAT3 signaling 65 circadian clock genes 65 NS5B 65 HDAC2 65 microvessel 65 extracellular domain 65 cyclic AMP cAMP 65 CTGF 65 bisulfite sequencing 65 mineralocorticoid receptor 65 TMEM#B 65 differentially expressed proteins 65 abnormal p# 65 PTEN gene 65 survivin 65 COX2 65 NQO1 65 tumorigenic 65 #F FDG 65 pyruvate kinase 65 SCD1 65 antitumor efficacy 65 GPR# [001] 65 VEGF expression 65 c Src 65 GNAQ 65 IgG4 65 MGMT gene 65 Inosine 65 CYP#B# 65 potent stimulator 65 Polymorphism 65 KIT mutations 65 C#BL 6 mice 65 EGF receptor 65 xenograft models 65 luciferase reporter 65 metastatic lymph nodes 65 hepatic lipase 65 FGFR1 65 factor HGF 65 transcriptional repressor 65 prostanoid 65 ncRNA 65 BEXXAR Therapeutic Regimen 65 BMAL1 65 Intracellular 65 Her2/neu 65 ALDH 65 K + ATPase 65 db db mice 65 PPARg 65 adenoviral 65 1α 65 KRAS mutations 65 RNA binding 65 cytochrome oxidase 65 Foxp3 65 prognostic significance 65 IL#B 65 cyclooxygenase 2 65 nNOS 65 comparative genomic hybridization 65 thymidine 65 GRNCM1 65 p# antigen 65 BMP4 65 pancreatic adenocarcinoma 65 VEGFR2 65 #β estradiol 65 gag pol 65 Tissue Factor 65 NR#A# 65 cDNA microarray 65 serum concentrations 65 galectin 65 stem cell pluripotency 65 hypermethylation 65 Antigen Specific 65 Immunohistochemistry 65 OGG1 65 genomic alterations 65 gene loci 65 dephosphorylation 65 tumoral 65 Cytoplasmic 65 Multivariate analysis 65 ER alpha 65 Subgroup analysis 65 immunoregulatory 65 FoxP3 65 IRE1 65 nucleolar 65 hENT1 65 dorsal root ganglion 65 genetic loci 65 C1q 65 PDE#A 65 Genotypic 65 causative mutations 65 Microtubule 65 triacylglycerol 65 amyloidogenic 65 GSTT1 65 thymidine kinase 65 kinase domain 65 protein encoded 65 vacuolar 65 5 HT1A receptor 65 Univariate analysis 65 superoxide dismutase 65 thromboxane A2 65 extracellular signal 65 IL 1β 65 adipokines 65 chimeric monoclonal antibody 65 apoptotic pathway 65 Bcl XL 65 cells transfected 65 pleiotropic 65 quantitative trait loci 65 esophageal carcinoma 65 polycystin 65 Nod1 65 steroidogenesis 65 FDG uptake 65 NS5b 65 amino acid residue 65 NMIBC 65 quantitative PCR 65 histone modifications 65 Vidaza ® 65 PTEN protein 65 FOXP3 65 lysyl oxidase 65 HBx 65 ß amyloid 65 transgenic mice expressing 65 GABAergic interneurons 65 IFN α 65 microglial activation 65 basolateral 65 PECAM 1 65 tumor histology 65 ubiquitylation 65 Histone deacetylase 65 BCL#A 65 CD# expression [002] 65 beta subunit 65 PARP inhibition 65 mTOR inhibitors 65 PBMCs 65 nucleolin 65 EGFR expression 65 Topoisomerase II 65 PSMA ADC 65 potently inhibits 65 TEL AML1 65 STAT3 activation 65 S. cerevisiae 65 p# mutations 65 SCID mice 65 splenocytes 65 CCR9 65 binds selectively 65 subcellular compartments 65 Src kinases 65 RQ PCR 65 EGFRvIII 65 peroxisomal 65 PKCi 65 NPRL2 65 Epigenomics proprietary 65 thymidylate synthase 65 glycosyltransferase 65 missense mutations 65 ALK inhibitors 65 phosphorylated tau 65 p# alpha [001] 65 immunofluorescence 65 pancreatic prostate 65 phosphatidylinositol 3 65 constitutive activation 65 Ad5FGF 4 65 renal cell carcinomas 65 ploidy 65 tumor suppressor protein 65 Stromal 65 Amino acid 65 EBNA1 65 CD3 + 65 unmutated 65 CD# + [001] 65 β catenin 65 intratumoral injection 65 regulated kinase 65 transfected cells 65 extramedullary 65 constitutively 65 alpha7 65 nitrotyrosine 65 pituitary adenomas 65 Cre recombinase 65 endogenous ligands 65 FGFs 65 Fibroblast Growth Factor Receptor 65 inhibits VEGF 65 immunotoxin 65 overexpressing 65 receptor subtypes 65 IDH1 mutation 65 SNCA 65 DNA hypermethylation 65 metastatic neuroendocrine tumors 65 hamartomas 65 synthases 65 Phenotypic 65 IGF1R 65 vascular endothelial cells 65 HER1 65 proteolysis 65 Aurora Kinase 65 Pgp 65 chemoresistance 65 GABRA2 65 metastatic malignant 65 glutamyl 65 LDL receptor 65 TGF β1 65 SELDI TOF MS 65 alpha#beta# integrin 65 E. faecalis 65 cytolytic 65 neoplastic cells 65 kallikrein 65 CHO cells 65 IL6 65 MEF2A 65 CYP#A# CYP#D# 65 factor PlGF 65 MCF7 65 IL8 65 genes differentially expressed 65 vivo potency 65 urocortin 65 mitochondrial respiration 65 dose dependently 65 RASSF1A 65 Wnt signaling pathway 65 downstream effector 65 sFlt 1 65 Mesenchymal 65 independent prognostic marker 65 TP# mutations 65 transfection efficiency 65 TrkB 65 striatal 65 sphingolipid 65 Inactivation 65 globin genes 65 calcium calmodulin dependent 65 posttranslational modification 65 HLA DR4 immune 65 ortholog 65 NO synthase 65 Prognostic factors 65 orally administered inhibitor 65 epididymal 65 transcriptional silencing 65 chromatin immunoprecipitation ChIP 65 pancreatic lung 65 BRCA1 BRCA2 65 trophoblasts 65 chromatin immunoprecipitation 65 neurturin 64 replicase 64 gene expression biomarkers 64 plasma pharmacokinetics 64 polynucleotides 64 apoptosis inducing 64 HER2/neu 64 phosphate S1P 64 erythropoiesis 64 metastatic gastric 64 granzyme B 64 ligand binding 64 Immunohistochemistry IHC 64 antiangiogenic agent 64 normal karyotype 64 NFκB 64 keratinocyte 64 CHEK2 64 Gleevec resistant 64 ductal adenocarcinoma 64 Lymph node 64 Dopaminergic 64 hematopoietic progenitor cells 64 cathepsins 64 CYP #D# 64 telomerase reverse transcriptase 64 metabolite concentrations 64 CCR1 64 LHRH receptors 64 KIAA# 64 xenograft tumors 64 oligomerization 64 Phylogenetic analysis 64 neural progenitor cells 64 myocardial necrosis 64 trophoblast 64 azacytidine 64 Polymerase 64 leukotriene B4 64 deacetylase 64 variant allele 64 cytolytic activity 64 Hypothalamic 64 Aâ 64 intestinal mucosal 64 focal adhesion kinase FAK 64 ubiquitin ligases 64 interferon IFN