TSC2

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(Click for frequent words.) 74 TSC1 69 Phosphorylation 68 pRb 67 constitutively expressed 66 phosphorylates 66 downregulates 66 ERK pathway 65 tyrosine phosphorylation 65 COL#A# 65 Upregulation 65 androgen receptor AR 64 NKX#.# 64 ERK1 2 64 regulated kinase ERK 64 Overexpression 64 cell adhesion molecule 64 H#K# methylation 64 upregulating 64 receptor tyrosine kinase 64 ERK signaling 64 mitogen activated protein kinase 64 PTPN# 63 MLH1 63 BMAL1 63 β catenin 63 CXCL# 63 proximal tubule 63 Oncogenic 63 extracellular signal 63 induced apoptosis 63 MSH2 63 GLUT4 63 proapoptotic 63 Pten 63 Kir#.# 63 overexpress 63 SMN1 63 JAK2 enzyme 63 Macrophage 63 vacuolar 63 mice lacking 62 induced phosphorylation 62 lysosomal 62 PTP1B 62 hyperactivation 62 SOCS3 62 MSH6 62 astrocytic 62 serine threonine kinase 62 Hedgehog signaling 62 Cathepsin B 62 peroxisomal 62 dependent protein kinase 62 virulence genes 62 NOTCH1 62 anterior pituitary 62 encodes protein 62 presynaptic 62 CEACAM1 62 E3 ligase 62 lymphangiogenesis 62 RNA binding 62 PTEN gene 62 Interferon gamma 62 proto oncogene 62 paxillin 62 Activating mutations 62 Histone 62 NFAT 62 transmembrane protein 62 ribosomal protein 62 phosphate dehydrogenase 62 Epithelial 62 serine threonine 62 tyrosine kinase receptor 62 hydroxylase 62 leptin receptor 62 constitutive activation 62 coexpression 62 LRAT 61 Extracellular 61 Transcription Factor 61 LRP5 61 cystic fibrosis transmembrane conductance 61 tumor suppressor protein 61 Dysregulation 61 LIS1 61 evolutionarily conserved 61 potent inhibition 61 R#W [002] 61 muscarinic receptors 61 Factor Receptor 61 leptin receptors 61 transferase 61 glyceraldehyde 3 61 downregulation 61 caveolin 1 61 synthetase 61 adhesion molecule 61 Purkinje cell 61 deacetylation 61 4E BP1 61 regulated kinase 61 beta actin 61 succinate dehydrogenase 61 CHD7 61 mRNA translation 61 FGFR3 61 FGFR4 61 cystic fibrosis transmembrane 61 autophagic 61 phospholipase A2 61 BRCA1 BRCA2 61 NFkB 61 pDC 61 methylenetetrahydrofolate reductase 61 Inactivation 61 T#M 61 aberrantly activated 61 homodimer 61 p# MAPK 61 MAP kinase 61 NKT cell 61 OCT4 61 granzyme B 61 MTHFR 61 carboxyl terminal 61 GSTP1 61 Drp1 61 dynactin 61 Smoothened 61 Drosha 61 GSTT1 61 G6PD 61 acinar 61 Arp2 3 61 transiently transfected 61 constitutively activated 61 Transmembrane 61 Klf4 61 subcellular localization 61 PKD1 61 cyclic AMP cAMP 61 GNAQ 61 polycystin 60 V#F mutation 60 ERa 60 Or#b 60 proteolysis 60 Nedd4 60 Cx# [001] 60 transcriptional repressor 60 potent inducer 60 VEGFR1 60 myocyte enhancer factor 60 adenylate cyclase 60 TMEM#B 60 somatostatin 60 coding genes 60 CaM 60 Dystrophin 60 Purkinje cells 60 metalloproteinase 60 EGFR signaling 60 tau phosphorylation 60 adenomatous polyposis coli 60 Secretase 60 ubiquitinated 60 prostaglandin synthesis 60 forkhead 60 At#g# 60 cell adhesion molecules 60 PI3K/Akt 60 Rho GTPases 60 PDGFR 60 inducible nitric oxide synthase 60 LRP6 60 transmembrane receptor 60 estrogen receptor alpha 60 triggers apoptosis 60 Sonic Hedgehog 60 basolateral 60 GAPDH 60 Apc 60 rs# [004] 60 methyltransferase 60 CYP#C# [002] 60 NF kB pathway 60 synaptogenesis 60 inherited mutations 60 receptor mediated endocytosis 60 nitric oxide synthase NOS 60 DNMT1 60 UCP1 60 Modulates 60 catenin 60 ß catenin 60 intergenic regions 60 transgenic mice expressing 60 LDL receptor 60 transduced 60 MMP9 60 c myc 60 decarboxylase 60 p# mitogen activated 60 PARP1 60 adipocyte 60 Nkx#.# 60 Dpp 60 cytokine signaling 60 MyD# 60 Polymorphisms 60 ectopic expression 60 ACC2 60 glucose transporter 60 copper zinc superoxide 60 Sp1 60 SIRT3 59 Tie2 59 Stromal 59 E#F# 59 Protein Kinase C 59 p#Kip# 59 mutant proteins 59 primary cilium 59 HIF 1alpha 59 mitogen activated protein kinases 59 kinase gene 59 SUMOylation 59 HIF 1α 59 TrkB 59 p# alpha [001] 59 Dopaminergic 59 TRIM5 59 FOXO 59 genes encoding 59 homodimers 59 phosphatidylinositol 3 59 alternatively spliced 59 EphB4 59 Streptococcus agalactiae 59 ornithine decarboxylase 59 ABCB1 59 TGF b 59 mRNA expression 59 DGAT1 59 secretory pathway 59 immunoreactive 59 homolog 59 KCNQ1 59 SMN1 gene 59 AT1R 59 antiapoptotic 59 differentially regulated 59 Signaling Pathway 59 1beta 59 Proteasome 59 cytidine 59 Microtubule 59 cyclin dependent kinase 59 PPARgamma 59 Synuclein 59 GTPase 59 plasminogen 59 constitutively active 59 Mice lacking 59 SCN5A 59 MEFs 59 #q#.# [002] 59 protein tyrosine phosphatase 1B 59 plasmacytoid dendritic cells 59 Calcineurin 59 GABAergic 59 FasL 59 phosphoinositide 59 downstream effector 59 receptor gamma 59 cypin 59 chemoattractant 59 baroreceptor 59 ERalpha 59 cellular prion protein 59 overactivation 59 LMNA 59 histone deacetylation 59 Rho GTPase 59 1alpha 59 Heterozygous 59 LKB1 59 MAPK pathway 59 syngeneic 59 sortilin 59 histone H4 59 transgene expression 59 RUNX3 59 uPAR 59 FUS1 59 hematopoietic progenitors 59 abnormal methylation 59 mediated inhibition 59 immunoreactivity 59 prolyl 59 TNFalpha 59 Smad3 59 kinase domain 59 transcriptional regulation 59 hypermethylation 59 severe congenital neutropenia 59 H#K# [002] 59 S#K# 59 synapse formation 59 lipoxygenase 59 Transgenic Mice 59 Tumor Suppressor 59 thioredoxin 59 c MET 59 Bmal1 59 regulator CFTR gene 59 iNOS 59 telomerase reverse transcriptase 58 ACVR1 58 neurite outgrowth 58 TRPV4 58 Nf1 58 glycosyltransferase 58 downstream effectors 58 telomere maintenance 58 caveolin 58 cytosolic 58 KCNE2 58 hypermethylated 58 enzyme AMPK 58 glucokinase 58 MAP kinases 58 telomeric 58 Rab5 58 Mutational 58 transactivation 58 Notch1 58 Fas ligand 58 coactivator 58 protein p# 58 antiproliferative activity 58 PIP2 58 miRNA genes 58 JAK STAT 58 FGFs 58 mRNA encoding 58 induces apoptosis 58 5 lipoxygenase 58 LPS induced 58 TORC2 58 Endothelial Cells 58 alpha subunit 58 rRNA 58 vitamin D receptor 58 circadian genes 58 PrPC 58 Intracellular 58 matrix metalloproteinase 58 transcriptional activation 58 thyroid peroxidase 58 PIP3 58 PI3K pathway 58 C#Y 58 trophoblast cells 58 leukocyte adhesion 58 Notch receptor 58 Hh pathway 58 BMP2 58 podocytes 58 Prox1 58 Immunohistochemical analysis 58 acetylcholine receptor 58 ERBB2 58 maternally inherited 58 PGC 1α 58 mitogenic 58 PECAM 58 colonic mucosa 58 phosphorylate 58 p# mutations 58 mTOR signaling 58 vimentin 58 cyclooxygenase COX 58 amino terminal 58 cytokine receptor 58 paralogs 58 potent inhibitors 58 Hypoxia Inducible Factor 58 chemotaxis 58 thymidylate synthase TS 58 anaphase promoting complex 58 Rb#/p# 58 apical membrane 58 autosomal recessive 58 Rap1 58 RNA polymerases 58 IKKß 58 focal adhesions 58 protein encoded 58 downregulated 58 genus Plasmodium 58 Neuronal 58 missense mutations 58 Epstein Barr Virus EBV 58 Sonic hedgehog 58 phosphatidylinositol 58 β1 58 mitochondrial gene 58 Vps# 58 MEK ERK 58 Rac1 58 acyltransferase 58 phosphoprotein 58 tensin homolog 58 neuroligins 58 β cells 58 thymidine kinase 58 Cdc# 58 homeobox 58 KRAS oncogene 58 Transcriptional 58 phosphatase 58 survival motor neuron 58 hepatic lipase 58 Progenitor Cells 58 cryopyrin 58 lymphoid organs 58 kinase pathway 58 osteoblast 58 NR2B subunit 58 regulates gene expression 58 S6K 58 EP4 58 receptor kinase 58 Pax6 58 missense 58 phospho 58 thrombospondin 58 prion protein PrP 58 Clusterin 58 microglial 58 tryptophan hydroxylase 58 cAMP dependent 58 retinoic acid receptor 58 TRAIL induced apoptosis 58 vesicle formation 58 transcriptional regulator 58 Neurotransmitter 58 F actin 58 NKG2D 58 p# activation 58 FKBP# 58 P2X 58 nAChRs 58 beta1 integrin 58 NADPH 58 WNK1 58 mosaicism 58 ataxia telangiectasia mutated 58 p# tumor suppressor 58 CYP #D# 58 TGF beta pathway 58 AMPA receptor 58 lysates 58 GLI1 57 fibulin 57 IFN γ 57 Fibroblast 57 activated protein kinase 57 HBx 57 IRAK1 57 transcriptional activity 57 prostanoid 57 mitogen activated protein 57 Polymerase 57 sinoatrial node 57 mesoderm 57 SMAD4 57 G#S [002] 57 STAT4 57 gamma H2AX 57 Germline 57 Dehydrogenase 57 subcellular compartments 57 cytoplasmic domain 57 PDGFR alpha 57 K ras mutations 57 LNCaP 57 DU# [002] 57 nAChR 57 PALB2 57 TACI 57 overexpressing 57 BRAF protein 57 stellate cells 57 hepatic glucose production 57 HCV replication 57 gene MECP2 57 carboxy terminal 57 phospholipase C 57 deacetylase 57 CAG repeats 57 p tau 57 HFE gene 57 beta subunit 57 microglial activation 57 lipid rafts 57 Caspase 57 endonuclease 57 gene encodes 57 JAK2 gene 57 CagA 57 polyamine 57 beta catenin protein 57 SH2 domain 57 E cadherin 57 endosomal 57 PIK3CA 57 histone methyltransferase 57 SETDB1 57 CDKN2A 57 Cytotoxic T 57 Skp2 57 HER2 HER3 57 caveolae 57 p# alpha [002] 57 noncoding RNAs 57 HepG2 cells 57 mineralocorticoid 57 Akt signaling 57 mitochondrial enzyme 57 Mice deficient 57 MLL2 57 presenilin 57 Oncogenes 57 #BP# 57 EAAT2 57 nephronophthisis 57 UCP2 57 c KIT 57 CDK5 57 cyclin dependent kinase inhibitor 57 homeobox gene 57 costimulatory 57 p#NTR 57 cytoskeletal protein 57 dephosphorylation 57 ankyrin repeat 57 somatic mutations 57 beta3 57 unmethylated 57 PC# cells 57 peptide receptor 57 serine proteases 57 kappa opioid receptors 57 Janus kinase 57 adipogenic 57 ciliated 57 chromosomal rearrangement 57 Cytoplasmic 57 Wnt signaling pathway 57 IFNg 57 paracellular 57 colorectal carcinoma 57 DSBs 57 tumor suppressor gene 57 IL 1β 57 Glycoprotein 57 vascular endothelial 57 HOTAIR 57 57 substrate specificity 57 selective inhibition 57 glucocorticoid receptor GR 57 NFKBIA 57 isomerase 57 Foxp3 57 Lyn kinase 57 neurofilament 57 promoter methylation 57 oncogenic transformation 57 cytochrome c oxidase 57 orthologs 57 metaphase 57 NFκB 57 PECAM 1 57 mediated phosphorylation 57 Differentially 57 p# MAP kinase 57 MAP kinase pathway 57 chromosome #q# [001] 57 murine leukemia virus 57 coding exons 57 cultured neurons 57 ERK phosphorylation 57 Integrins 57 suprachiasmatic nucleus 57 COX2 57 Frizzled 57 PAK1 57 chromosomal regions 57 Tyrosine Kinase 57 proteosome 57 frameshift mutation 57 perivascular 57 MeCP2 gene 57 osteoclast activity 57 actinin 57 casein kinase 57 missense mutation 57 TFIIH 57 motor neuron degeneration 57 poly ADP ribose polymerase 57 hematopoietic progenitor cells 57 intestinal epithelial cells 57 Hsp# [001] 57 MEK1 57 #q# deletion 57 homologues 57 Inhibits 57 apoptotic pathway 57 Cyclin D1 57 Catenin 57 hnRNP 57 histone H3 57 inactive X chromosome 57 upregulation 57 Chromosomal 57 histone modification 57 heterodimer 57 trophoblast 57 Mesenchymal 57 upregulated 57 messenger RNAs 57 JNK1 57 melanocyte 57 superoxide dismutase 57 leucine zipper 57 PKC isoforms 57 heterochromatic 56 serine protease 56 Lymphocytic 56 gene encoding 56 TIMP 56 leptin signaling 56 sphingolipid 56 cellular metabolism 56 mutated p# 56 exocrine glands 56 tumorigenesis 56 coronary vasodilation 56 protein phosphorylation 56 interferon pathway 56 DNA methyltransferases 56 TGF ß 56 synthetases 56 glutamate receptors 56 c Src 56 enzymatic activity 56 piRNAs 56 constitutively 56 protein secreted 56 catalytic subunit 56 isoleucine 56 IRS1 56 gene locus 56 GlcNAc 56 Smad 56 ERK2 56 Dictyostelium discoideum 56 SOD1 protein 56 Trypanosoma brucei 56 induce pluripotency 56 apoE 56 Notch signaling 56 epigenetic modifications 56 non coding RNA 56 intestinal epithelium 56 polyadenylation 56 splice variants 56 phosphorylated tau 56 mitochondrial fragmentation 56 MAP#K# 56 receptor subtypes 56 Mcl 1 56 tyrosine kinase 56 heterozygotes 56 μ opioid receptor 56 intracellular signaling 56 Transcription factors 56 Tyrosine 56 polycystin 1 56 apo AI 56 Wnt#b 56 DDB1 56 Reductase 56 gag pol 56 NR#A# 56 hypomethylation 56 chromatin remodeling 56 transmembrane domains 56 FOXP3 56 histone acetylation 56 lysine residues 56 Huntingtin 56 herpesviruses 56 reductase 56 receptor subunit 56 apolipoprotein E4 56 hemagglutinin H 56 alveolar epithelial cells 56 misregulation 56 CPEB 56 hepatoma 56 replicon 56 XBP 1 56 transcriptional repression 56 MAPK 56 myoepithelial 56 capillary endothelial cells 56 chemokine receptor 56 EZH2 56 Cadherin 56 upregulate 56 FGF signaling 56 TOP2A gene 56 CTLs 56 SLC#A# [001] 56 connexin 56 γδ T cells 56 #beta HSD1 56 oncogenic signaling 56 osteogenic differentiation 56 Methylation 56 Arf gene 56 glutathione S transferase 56 caspase activation 56 retinoblastoma protein 56 folate receptor 56 glycolipids 56 IKK 56 condensin 56 FMR1 gene 56 TP# gene 56 epigenetic silencing 56 Brain derived neurotrophic 56 ribosomal DNA 56 N myc 56 homologous recombination 56 ENaC 56 Tuberous sclerosis 56 endocytic 56 disulfide bond 56 mRNA transcripts 56 Secretion 56 CFTR gene 56 replicase 56 eIF2 56 RTKs 56 Akt phosphorylation 56 MLL gene 56 inflammatory cytokine 56 eIF4E 56 peroxisome 56 glutamate receptor 56 NF KappaB 56 Mammalian 56 ubiquitination 56 Secretory 56 epigenetic alterations 56 glutamic acid decarboxylase 56 PDGF receptor 56 calpain 56 hyperphosphorylation 56 innate immune responses 56 E1A 56 IKK beta 56 hydrolases 56 chromosome #q 56 C#T [002] 56 receptor protein 56 P selectin 56 promoter hypermethylation 56 PP2A 56 NF κB 56 ubiquitylation 56 TGFβ 56 intracellular signal transduction 56 #S rRNA 56 centromeric 56 mitotic catastrophe 56 TNFR 56 MAPKs 56 p# mutation 56 breast epithelial cells 56 methyl CpG binding 56 glutamatergic 56 HER2 neu 56 Cystic Fibrosis Transmembrane conductance 56 Endothelial 56 Vpr 56 PPARg 56 CDK4 56 cells transfected 56 TRAF6 56 embryonal carcinoma 56 NR2B 56 Cdc7 56 brain neurotransmitter 56 threonine 56 chromosome #q#.# [001] 56 virulence determinants 56 MnSOD 56 haematopoietic 56 protein tyrosine kinase 56 Htt 56 FGF ligands 56 miR #a [001] 56 tumor suppressor p# 56 fatty acid synthase 56 transthyretin TTR 56 BubR1 56 coiled coil domain 56 HIV reverse transcriptase 56 retinoblastoma Rb 56 demethylase 56 phosphorylase 56 cysteines 56 endogenous ligands 56 synthases 56 GPC5 56 TET2 56 Escherichia coli Klebsiella pneumoniae 56 cyclooxygenase 56 SCN1A 56 Alleles 56 Angiotensin II 56 monogenic 56 mPGES 1 56 coreceptor 55 Cytochrome 55 GTP hydrolysis 55 GABAergic interneurons 55 BRAF gene 55 CDKs 55 pharmacological inhibition 55 microcephalin 55 null mice 55 X inactivation 55 keratinocyte 55 abnormal angiogenesis 55 CREBBP 55 eNOS 55 GenBank accession 55 synaptic transmission 55 paracrine 55 #p#.# [002] 55 sensory axons 55 NF1 gene 55 syntaxin 55 Src 55 enterocytes 55 Lkb1 55 pheromone receptor 55 hypothalamic pituitary adrenal axis 55 apoE4 55 PTEN phosphatase 55 bFGF 55 CCR7 55 oncoprotein 55 neuronal plasticity 55 RNA splicing 55 histone deacetylases 55 KLF4 55 MDR1 55 transmembrane 55 Vpu 55 lymphoid cells 55 sequence homology 55 SNARE proteins 55 Synthase 55 Treg cells 55 PDE#A 55 Inflammatory Pain 55 embryonic tissues 55 protein tyrosine phosphatase 55 Glucocorticoid 55 SIRT4 55 GATA1 55 trimeric 55 Nuclear Receptor 55 IGFBP2 55 amyloidogenic 55 aminopeptidase 55 XPB 55 overexpression 55 RAD# [001] 55 nucleotide sequence 55 huntingtin 55 mediated apoptosis 55 activating mutation 55 TCF#L# 55 vascular endothelial cells 55 MiRNAs 55 Sox9 55 Ras pathway 55 p# subunit 55 TGF β 55 proviral 55 immunoblotting 55 microtubule associated 55 Wnt 55 metalloprotease 55 vomeronasal 55 EphA2 55 FLT3 55 gene encodes protein 55 HIF 2alpha 55 pulmonary metastases 55 Olig2 55 Kupffer cells 55 PML RARA 55 progranulin gene 55 endothelial nitric oxide synthase 55 Cyclooxygenase 2 55 HepG2 55 biogenesis 55 chromosomal aberrations 55 c myb 55 NS5A 55 VEGF receptor 55 PPARγ 55 chromosome #q# [002] 55 microtubule dynamics 55 somatic mutation 55 nucleolar 55 PPAR peroxisome proliferator activated 55 glycogen synthase kinase 55 chemotactic 55 breast cancer genes BRCA1 55 insulin signaling pathways 55 TCF#L# gene 55 Src kinases 55 budding yeast 55 cholinergic neurons 55 bacterium Escherichia coli 55 proteolytic cleavage 55 lyase 55 SLC#A# gene [002] 55 transgenic mouse model 55 hippocampal cells 55 oxytocin receptor 55 Mouse Model 55 5' monophosphate 55 mucins 55 RASSF1A 55 BRAF V#E 55 calcium calmodulin dependent 55 Phosphatase 55 renal fibrosis 55 centromeres 55 chaperone proteins 55 gene polymorphism 55 PBMCs 55 Hh 55 homozygotes 55 ncRNA 55 VE cadherin 55 Eukaryotic 55 unmutated 55 SHANK3 55 XBP1 55 Kinases 55 MECP2 gene 55 NKX2 55 TNF α 55 microRNAs miR 55 KSHV 55 beta globin 55 posttranslational modification 55 Protein Kinase 55 Cdx2 55 mutated K ras 55 glutamatergic neurons 55 mutant huntingtin protein 55 lung epithelial cells 55 fatty acid synthesis 55 perilipin 55 H#K#me# 55 monocytes macrophages 55 CArG 55 myeloid 55 FGFR2 55 Chinese hamster ovary 55 cAMP signaling 55 dendritic cells DCs 55 beta amyloid peptide

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