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(Click for frequent words.) 62 E#F# 62 Foxp3 60 NKT cell 60 MT1 MMP 60 catenin 60 transmembrane protein 59 JAK STAT 59 BMAL1 59 Rap1 59 tyrosine phosphorylation 59 BMP signaling 59 Vps# 59 phosphorylates 59 protein tyrosine phosphatase 59 TGF β 59 monocyte 59 Sox9 59 MAPK pathway 59 melanocyte 59 androgen receptor AR 59 c MYC 59 Dystrophin 59 constitutively active 59 MEK1 58 tumor suppressor protein 58 CD1d 58 uPAR 58 transmembrane receptor 58 NF kappaB activation 58 SIRT2 58 MyoD 58 modulatory 58 glycosyltransferase 58 RhoA 58 MAP kinase 58 transactivation 58 SMN1 58 Id1 58 pDCs 58 catalytic subunit 58 HIF 1alpha 58 coactivator 58 occludin 58 transcriptional repressor 58 ubiquitination 58 VEGF receptor 58 ectopic expression 58 c myc 58 Htt 58 constitutively 58 T#M 57 transcriptional regulators 57 survivin 57 phosphorylate 57 HDAC2 57 Notch1 57 Caspase 57 CXCL# 57 methyltransferase 57 SOX9 57 osteoblast 57 siRNA mediated 57 TG2 57 VE cadherin 57 PIP2 57 syntaxin 57 HERV 57 #β HSD1 57 TAp# 57 beta subunit 57 c Src 57 HIF 1a 57 apoptotic pathway 57 EP4 57 chemokine receptor 57 serine protease 57 virulence genes 57 LIS1 57 NKX#.# 57 Vpr 57 evolutionarily conserved 57 estrogen receptor alpha 57 oncogenic transformation 57 transcriptional activation 57 ligase 57 beta globin 57 cardiac fibroblasts 57 STAT1 57 iNOS 56 VEGFR1 56 adhesion molecule 56 nucleolar 56 coexpression 56 proto oncogene 56 serine threonine kinase 56 eIF2 56 p#NTR 56 recombinase 56 cell adhesion molecule 56 Nampt 56 phosphatase 56 GSK 3ß 56 X inactivation 56 ribosomal protein 56 ZBP1 56 TIMP 1 56 alpha secretase 56 β catenin 56 intracellular signaling 56 XBP1 56 cathepsins 56 glucocorticoid receptor 56 Catenin 56 cytoskeletal structure 56 KLF# 56 hnRNP 56 E1A 56 receptor tyrosine kinase 56 pRb 56 leptin signaling 56 Wnt signaling pathway 56 oncoprotein 56 Math1 56 cell receptor TCR 56 SOCS3 56 ERK1 2 56 IKKß 56 EBNA1 56 Six3 56 adipogenic 56 COX2 56 actin cytoskeleton 56 extracellular signal 56 CaM 56 E3 ubiquitin ligase 56 noncoding RNA 55 tRNA synthetase 55 MMP2 55 SREBP 55 thrombospondin 55 RSK2 55 alpha subunit 55 SUMOylation 55 IRAK1 55 cardiomyocyte 55 oligomerization 55 CTLs 55 Phosphorylation 55 miR #a [002] 55 PKD1 55 caveolin 55 ER alpha 55 FGFR4 55 NKG2D 55 substrate specificity 55 metabolic enzymes 55 nucleolin 55 selectively binds 55 H#K# [002] 55 adipogenesis 55 Notch signaling 55 ras gene 55 DNA ligase 55 trophoblast 55 Rb#/p# 55 sonic hedgehog 55 E3 ligase 55 Kv#.# 55 MMP# 55 NOTCH1 55 cytokine signaling 55 mutant huntingtin protein 55 cytidine 55 BCL#A 55 MDM2 55 JAK2 enzyme 55 Stat3 55 TH1 55 deacetylation 55 ERK pathway 55 chaperone proteins 55 EGFP 55 Integrins 55 p# mitogen activated 55 RNA polymerases 55 kinase pathway 55 tumor antigen 55 cyclins 55 TNFR 55 A3G 55 membrane proximal 55 colocalization 55 NF κB 55 junctional 55 Flt3 55 FAK 55 LKB1 55 STAT3 55 Cyclin D1 55 GTPase 55 Integrin 55 Bcl 55 trimeric 55 MMP9 55 UCP2 55 Th2 55 microglial activation 55 Mdm2 55 interneurons 55 Cx# [001] 55 phagocyte 55 CCL# 55 TGF ß 55 clonogenic 55 rRNA 55 ubiquitylation 55 aromatase 55 histone H3 54 cAMP signaling 54 GRP# 54 TrkB 54 metalloproteinases 54 Smoothened 54 Sonic hedgehog 54 tyrosine kinase receptor 54 Protein Kinase C 54 T lymphocyte 54 receptor molecule 54 protein p# 54 FoxO1 54 Upregulation 54 Microtubule 54 5 lipoxygenase 54 ADAM# 54 oncogenic 54 IGF IR 54 S#K# 54 neuromuscular junction 54 globin gene 54 casein kinase 54 pDC 54 MicroRNA 54 Vpu 54 receptor kinase 54 beta adrenergic receptors 54 mitogen activated protein kinases 54 actin polymerization 54 TNFalpha 54 HDAC3 54 KLF4 54 integrins 54 Sonic Hedgehog 54 STAT5 54 cytoplasmic domain 54 p# subunit 54 Cytotoxic T 54 kinesin motor 54 SMN2 54 microRNAs miRNAs 54 cytoplasmic tail 54 EZH2 54 cyclooxygenase 2 54 RANK ligand 54 corpus luteum 54 cAMP 54 TNFα 54 mGluR 54 focal adhesion kinase 54 HOTAIR 54 heterologous 54 Cytochrome 54 inhibitory receptor 54 Arp2 3 54 murine 54 MALAT1 54 mitogen activated protein kinase 54 telomerase gene 54 Src 54 matrix metalloproteinase 54 cyclic AMP cAMP 54 Akt activation 54 CD#b 54 ESCRT 54 mRNA transcripts 54 cystic fibrosis transmembrane conductance 54 furin 54 PTPN# 54 caveolin 1 54 ribonuclease 54 MAPK 54 Runx1 54 adrenoceptor 54 downstream effector 54 cdk5 54 interleukin IL 54 6S RNA 54 IGFBP2 54 homodimer 54 BMP4 54 IgG1 54 PTP1B 54 constitutively activated 54 transferase 53 tumor suppressor 53 DGAT1 53 RASSF1A 53 utrophin 53 MAPKs 53 morphogen 53 NFAT 53 homolog 53 epigenetically 53 GAPDH 53 Wnt pathway 53 AMACR 53 enzymatic activity 53 Transcription Factor 53 cysteine residues 53 CatB 53 isoenzyme 53 Rac1 53 NFkB 53 receptor CXCR4 53 nAChR 53 Cre recombinase 53 gluconeogenesis 53 GPR# [002] 53 nicotinic receptor 53 Î ² 53 IKK beta 53 chaperone protein 53 glutamate receptors 53 Rho kinase 53 ACh 53 glucocorticoid receptor GR 53 Nanog 53 IGF1R 53 PAX5 53 Fig. 1D 53 cyclic AMP 53 ligand binding 53 ribonucleotide reductase 53 cyclophilin D 53 estrogen receptor beta 53 exonuclease 53 cell adhesion molecules 53 gene p# 53 COL#A# 53 Neuropeptide Y 53 μ opioid receptor 53 autocrine 53 activin 53 cadherin 53 FOXP3 53 enterocytes 53 Runx2 53 prostaglandin E2 PGE2 53 DMT1 53 SIRT6 53 MDSCs 53 calcineurin 53 TEL AML1 53 reductase 53 Skp2 53 splice variants 53 GRK2 53 TrkA 53 protein phosphatase 53 alveolar macrophages 53 endonuclease 53 Oncogenic 53 scavenger receptor 53 dynamin 53 pyruvate kinase 53 Shh signaling 53 chromosome condensation 53 MYCN 53 TGFß 53 C EBP alpha 53 receptor signaling 53 S#A# [002] 53 R#W [002] 53 glucose transporter 53 globin 53 germline mutation 53 Notch receptor 53 transgenic mice expressing 53 phosphorylated 53 RNA transcripts 53 TH2 53 mRNA encoding 53 MEF2A 53 Polymerase 53 EGFRvIII 53 GATA3 53 p# MAPK 53 cyclin 53 isoleucine 53 phosphoinositide 53 TFIIH 53 peptidase 53 Germline 52 TGFβ 52 NS5A 52 5' triphosphate 52 receptor CD# 52 Smad3 52 leptin receptor 52 Smurf1 52 cortisol receptor 52 myocyte enhancer factor 52 adipokine 52 myeloid cells 52 synapse formation 52 HepG2 cells 52 Epithelial 52 HGF 52 IRE1 52 overexpressing cells 52 p# p# 52 heterodimers 52 LSD1 52 synaptotagmin 52 Muscarinic 52 MEFs 52 DLX5 52 ubiquitin ligase 52 mesenchymal cells 52 Th1 cells 52 aminopeptidase 52 immunoreactivity 52 glucokinase 52 1alpha 52 Kinases 52 PI3K signaling pathway 52 Syk 52 ErbB4 52 glutamate signaling 52 Cdc# 52 FGFR1 52 transgenic mouse model 52 postsynaptic 52 TRIM# 52 adenosine receptor 52 dimerization 52 Smad4 52 guanosine 52 POMC neurons 52 Mutational 52 PTEN gene 52 matrix metalloproteinases MMPs 52 NR2B subunit 52 antigenic epitopes 52 SAP# 52 heterodimer 52 mRNA decay 52 anterior pituitary 52 effector 52 NF κB activation 52 micro RNAs 52 osteocalcin 52 CD# CD# 52 connexin 52 Nrf2 52 cytoskeletal 52 adrenergic receptors 52 PDGFR 52 coiled coil domain 52 ciliary 52 cyclin D1 52 E cadherin 52 leucine zipper 52 nitric oxide synthase NOS 52 HEK# cells 52 protein encoded 52 B7 H4 52 endonucleases 52 Ubx 52 SGK1 52 MLL gene 52 pyramidal neurons 52 cortical neurons 52 demethylation 52 annexin 52 V3 loop 52 cyclin B1 52 Fig. 4a 52 Factor NGF 52 bispecific 52 PIP3 52 cytokine secretion 52 PcG proteins 52 transcriptionally 52 Vif 52 MAP kinase pathway 52 MEF2 52 mesenchyme 52 plasminogen activator 52 RUNX3 52 muscarinic receptor 52 Supplemental Figure 52 messenger molecule 52 ARF1 52 TEP1 52 PrP 52 IFNg 52 androgen receptor 52 calpain 52 Topoisomerase 52 TGFbeta 52 FGF# 52 LDLR 52 integrin 52 histone protein 52 protein kinase C 52 5 HT1A 52 Myelination 51 TORC2 51 transmembrane 51 caspases 51 p#Kip# 51 Macrophage 51 RNase H 51 antigen binding 51 EGFR signaling 51 KLF2 51 #HT#A 51 transcriptional coactivator 51 EphB4 51 leukocyte recruitment 51 amino terminal 51 lysyl oxidase 51 Histone 51 51 presynaptic 51 M1 muscarinic 51 RANKL 51 tyrosine kinase 51 Tumor Necrosis Factor 51 Pax6 51 pericytes 51 NF kappaB 51 cytoskeletal protein 51 CD4 + CD# 51 cGPS ® 51 operon 51 CaMKII 51 FABP 51 kinase domain 51 protein tyrosine kinase 51 acyltransferase 51 Androgen receptor 51 amino terminus 51 peroxisomes 51 interferon pathway 51 LRP5 51 membrane glycoprotein 51 Fig. 3b 51 NK1R 51 glucocorticoid receptors 51 CDK4 51 heterochromatic 51 thyroid hormone receptor 51 OGG1 51 glutamate receptor 51 mesoderm 51 astrocyte 51 SWI SNF 51 adenylyl cyclase 51 mitochondrial respiration 51 Signaling Pathway 51 gene encodes protein 51 tyrosinase 51 Pten 51 adenylate cyclase 51 LRP6 51 ERa 51 COOH terminal 51 murine monoclonal antibody 51 PECAM 51 receptor gamma 51 focal adhesion 51 ABCA1 51 Rab# 51 Polycomb 51 Lhx2 51 Sox2 51 exocytosis 51 tumor suppressor gene 51 Kinase 51 intracellular proteins 51 kDa 51 CD#L 51 tyrosine hydroxylase 51 microtubule dynamics 51 Jurkat cells 51 transcription factors 51 RNA polymerase II 51 ectodomain 51 DU# [002] 51 inflammatory cytokine 51 hypoxia inducible transcription 51 centromeric 51 downregulation 51 D. melanogaster 51 cell signaling pathway 51 EGF receptor 51 fibronectin 51 major histocompatibility complex 51 c Abl 51 Mesenchymal 51 Wnt 51 epithelial stem cells 51 PAR1 51 arginase 51 Ras pathway 51 SIRT3 51 BCL6 51 homologs 51 serotonin receptor 51 adduct 51 tumor suppressors 51 hedgehog signaling 51 Inducible 51 RAD# [001] 51 p#INK#a 51 Cathepsin B 51 TGF beta pathway 51 GTP hydrolysis 51 intron 51 Wnt signaling 51 c Fos 51 Myosin 50 tetherin 50 GATA1 50 protein kinase 50 chemokine SDF 1 50 phospholipase 50 Argonaute 50 Ca2 + 50 ligand receptor 50 immunostimulatory 50 Neurogenesis 50 RecA 50 Endothelial 50 Mice deficient 50 cytochrome c 50 X Chromosome 50 Differentially 50 Extracellular 50 Wnts 50 CIB1 50 ESR1 50 glycan 50 avidin 50 PON1 50 HMG CoA reductase 50 lipid rafts 50 huntingtin protein 50 p# gene 50 claudin 50 secretase 50 PAK1 50 peptide receptor 50 myofibroblast 50 MeCP2 50 kinase enzymes 50 Bruton tyrosine kinase 50 allelic variants 50 fascin 50 ephrin 50 presenilin 50 chromatin remodeling 50 HMGA2 50 Fibroblast Growth Factor 50 serpin 50 Nkx#.# 50 Cell Receptor 50 activated macrophages 50 potassium ion 50 gp# [002] 50 transfected 50 NMDA receptor 50 Tie2 50 endoplasmic reticulum stress 50 5 HT2A receptor 50 olfactory receptor 50 AMPA receptors 50 protein fragment 50 mammary stem cells 50 conformational changes 50 carcinoembryonic antigen 50 clade C 50 c Myc 50 repressor 50 costimulatory molecules 50 Th1 type 50 ChR2 50 TSLP 50 P#X# 50 acetylcholine receptors 50 ORFs 50 amino acid residues 50 kappa B 50 mPGES 1 50 phosphoprotein 50 Modulators 50 GTPases 50 catalase 50 CXCR2 50 TGF beta 50 kinase substrate 50 beta arrestin 50 focal adhesion kinase FAK 50 histone 50 glycoprotein 50 biotinylated 50 transduced 50 CHD5 50 Wnt beta catenin 50 orthologs 50 Ang2 50 STIM1 50 Th2 cells 50 NS1 50 vWF 50 semaphorin 50 resistin 50 amino acid substitutions 50 regulating gene expression 50 TERT 50 Rb gene 50 extracellular domain 50 Lrp5 50 stromal cells 50 calcium ion 50 CDK8 50 phosphatidylinositol 50 Neurotransmitter 50 RNAP 50 protein conformation 50 cannabinoid receptor 50 Alu elements 50 Interferon gamma 50 OCT4 50 miR# 49 osteopontin 49 CpG island 49 heterozygotes 49 WT1 49 dependent protein kinase 49 Cyclic AMP 49 Protein kinase 49 phospholipase C 49 Nucleotide 49 SIRT1 gene 49 valine 49 homology 49 Transcriptional 49 dinucleotide 49 uracil 49 Oncogenes 49 overexpression 49 mitochondrial gene 49 PI3K Akt 49 ErbB 49 xenograft model 49 Pdx1 49 C#Y 49 nucleolar dominance 49 hyperactivated 49 Epidermal Growth Factor Receptor 49 neurone 49 PI3 Kinase 49 PTEN phosphatase 49 Bone marrow derived 49 FOXM1 49 c fos 49 proNGF 49 transthyretin 49 signaling cascade 49 PKC alpha 49 thioredoxin 49 TSP1 49 UCP1 49 mammaglobin 49 neurexin 49 Cytoplasmic 49 BMP receptor 49 lacZ 49 IRS1 49 Intracellular 49 cytochrome 49 caveolae 49 Modulating 49 GABAergic neurons 49 Hox gene 49 effectors 49 succinate dehydrogenase 49 inflammatory cytokines 49 immunofluorescence staining 49 RNase 49 Notch pathway 49 ryanodine receptor 49 fibrogenesis 49 ssDNA 49 polyadenylation 49 hepatocyte growth 49 Glial 49 BACE1 49 PKM2 49 Nrf2 pathway 49 miRNAs 49 fig. S2 49 Myc 49 gB 49 lipid homeostasis 49 CatSper 49 Alu RNA 49 mechanotransduction 49 Fig. 1C 49 MUC1 49 Hh 49 metabotropic glutamate receptors 49 intergenic 49 3' 49 short hairpin RNA 49 opioid receptor 49 silencing RNA 49 aldose reductase 49 connexin# 49 FGF2 49 KSHV 49 transmembrane domain 49 Frizzled 49 adipose cells 49 viral genome 49 polypeptide 49 kappa opioid receptor 49 adhesion molecules 49 tumor suppressor p# 49 KEAP1 49 NS3 49 IL2 49 tRNA 49 Atoh1 48 TRPM8 48 aspartyl 48 antisense oligonucleotide 48 reversibly 48 amyloid fibrils 48 microRNA miRNA 48 activating receptors 48 DEAR1 48 Eukaryotic 48 potently inhibits 48 Cell Proliferation 48 MDMX 48 Ubiquitin 48 downstream effectors 48 TRIM5 alpha 48 retrotransposon 48 PMR1 48 NFKB 48 CDKN2A 48 rabbit polyclonal 48 receptor gene 48 mammary cancers 48 Pax3 48 Akt1 48 PEPCK 48 FOXP3 gene 48 melanocyte stimulating hormone 48 IGF2 48 Akt 48 5 hydroxytryptamine 48 EphB2 48 ceramide 48 tumor microenvironment 48 Tumor Suppressor 48 fig. S1 48 thrombin receptor 48 TRPV3 48 haemagglutinin 48 mutant protein 48 Cytokine 48 sphingomyelin 48 HER2 HER3 48 transcriptional activity 48 PGE2 48 CB2 receptors 48 beta1 48 plasma membrane 48 NEDD8 48 Bcl xL 48 Neuronal 48 intercellular adhesion molecule 48 neuronal membranes 48 NRF2 48 radial glia 48 deletion mutant 48 epigenetic alterations 48 multidomain 48 G quadruplex 48 tyrosine phosphatase 48 angiotensin II receptor 48 lysine residues 48 Glucocorticoid 48 RNA polymerase 48 GluR1 48 malonyl CoA 48 Mitochondrial 48 nucleotide sequence 48 Figure 1A 48 Hsp# chaperone 48 osteocytes 48 estrogen receptor 48 SRY 48 gene expression 48 NF kB pathway 48 amacrine 48 Smad proteins 48 fission yeast 48 MDCK cells 48 amyloid β 48 aP2 48 HGF c Met 48 inhibitory 48 BrdU 48 melatonin receptors 48 Protein Interactions 48 cryopyrin 48 NF kB 47 C#BL 6 47 encodes protein 47 PDGF alpha receptor 47 σ 47 morphogens 47 lactamases 47 cultured rat 47 IKKa 47 Fig. 2C 47 HDAC enzymes 47 gonadotrophin releasing hormone 47 serotonin transporter 47 cytokine 47 neuropeptides 47 FLT3 kinase 47 proteins 47 protein myosin 47 PPAR gamma 47 DHPLC 47 subunit 47 WNT pathway 47 Supplementary Fig 47 Fig. 3B 47 mRNA 47 A#V 47 glucocorticoid 47 synaptic 47 G#S [002] 47 PAM4 47 integrin alpha 4 47 meiotic recombination 47 NRTI resistance 47 carboxypeptidase 47 stromal derived 47 transcriptional activator 47 Annexin 47 MYBPC3 47 covalently attached 47 Cyclooxygenase 2 47 amyloid beta peptides 47 Cyclin E 47 Chk1 47 Wnt#b 47 glycoproteins 47 microsatellite instability 47 NF kappa B 47 Gamma secretase 47 menin 47 CD# receptor 47 reverse transcriptase 47 apoptosis proteins 47 heme oxygenase 1 47 amygdala neurons 47 coding sequences 47 Cell Adhesion 47 polymerase 47 Figure 1C 47 PGC 1alpha 47 TRPA1 receptor 47 potent inhibition 47 beta defensin 47 fusion proteins 47 osteoblasts 47 signaling molecule 47 tumor suppressor genes 47 neuropeptide Y NPY

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