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(Click for frequent words.) 70 oral salmon calcitonin 70 Enhanze Technology 69 5 HT3 antagonist 68 liposomal formulation 68 Zuplenz 68 VISICOL R 67 RECOTHROM R 67 Restoraderm 67 transdermal gel 67 intranasal formulation 67 topical ophthalmic 67 Fortical R 67 transdermal spray 67 NeuroSTAT ® 67 subcutaneous formulation 67 proprietary transdermal 67 Perforomist ™ Inhalation Solution 66 ATD gel 66 zileuton 66 capsule formulation 66 topical formulation 66 Emezine 66 INTELLITAB TM 66 Linjeta TM 66 injectable depot 66 ferumoxytol Injection 66 orally disintegrating tablet 66 MoxDuo 66 antiarrhythmic agent 66 OSMOPREP 66 PRT# 66 ZEGERID Capsules 66 orally disintegrating tablets 66 NexACT ® 66 XOPENEX HFA 66 orally inhaled 66 topiramate Topamax 66 patented Bioral 66 topical formulations 66 lingual spray 66 inhibitor PPI 66 oral transmucosal 66 octreotide acetate 65 acetonide FA 65 NanoEmulsion 65 pharmacodynamic properties 65 reslizumab 65 intranasal delivery 65 OMNARIS Nasal Spray 65 Aloxi R 65 PDE4 inhibitor 65 topical antifungal 65 TRISENOX ® 65 intravenous formulations 65 Saizen R 65 Combo Stent 65 biodegradable implant 65 injection USP 65 anti infective treatments 65 SARMs 65 Contramid 65 Proquin XR 65 orally disintegrating 65 adenosine injection 65 Serostim ® 65 Cyclosert 65 sumatriptan DosePro 65 TLK# 65 PharmFilm ® 65 Vaxfectin TM 65 oxybutynin gel 65 Dual Opioid TM 65 EpiCeram 65 oral prodrug 65 PTH1 65 Veregen TM 65 Orally administered 65 Dual Opioid 65 PolyActive ® 65 DUROS 65 Nektar pulmonary 65 Azedra 65 Alexza Staccato 64 transdermal delivery 64 vapreotide acetate 64 CAPHOSOL R 64 DURECT proprietary 64 INKP 64 oral taxane 64 neuroprotective properties 64 ADP receptor antagonist 64 histamine dihydrochloride 64 INT# [002] 64 SUMAVEL 64 MOVIPREP R 64 ActiPatch Therapy 64 DsiRNA 64 NanoTab 64 proton pump inhibitor PPI 64 Eligen ® Technology 64 systemic immunosuppressive drugs 64 paclitaxel Taxol ® 64 rxRNA ™ compounds 64 Sumatriptan Succinate 64 Xanafide 64 muco adhesive technology 64 PolyActive 64 Zelapar 64 Tekturna HCT 64 RFF Pen 64 BEMA Granisetron 64 MoxDuo IR 64 Amplimexon 64 inhaled formulation 64 liposomal formulations 64 transmucosal delivery 64 pharmacologically active isomer 64 targeted antifolate 64 Gel repository corticotropin injection 64 AzaSite Xtra 64 AMMONUL R sodium phenylacetate 64 Pennsaid R 64 Locked Nucleic Acid LNA 64 Leukine ® 64 Cetuximab Erbitux 64 Altera Nebulizer System 64 Civacir 64 ACUROX ® 64 methylnaltrexone bromide 64 convenient dosing regimens 64 dihydrochloride 64 Transdel TM 63 successfully commercialize Iluvien 63 Soriatane 63 TRANSDUR ™ 63 S1P antibody 63 Nexavar sorafenib tablets 63 Mycamine 63 Intravail R 63 Foradil Aerolizer 63 Levetiracetam 63 docetaxel Taxotere ® 63 novel oral anticoagulant 63 granisetron 63 mometasone 63 Accordion Pill 63 fluoroquinolone antibiotic 63 TriRima 63 sublingual tablets 63 Zingo TM 63 VersaFilm 63 nasal antihistamine 63 salmon calcitonin 63 TELINTRA 63 metered dose 63 LEX System 63 Novasome R 63 Twinject ® 63 prednisolone sodium phosphate 63 Orapred ODT 63 Allovectin 7 r 63 TPI ASM8 63 rxRNA 63 efficacy tolerability 63 SNALP technology 63 PEGylation technology 63 INTEGRILIN ® 63 Locteron ® 63 OMNARIS HFA 63 pioglitazone HCl 63 Lauriad 63 Cefepime 63 DuraSite R 63 brand ciclesonide HFA 63 Topical Suspension 63 lapatinib Tykerb 63 Myocet 63 PHX# 63 Dabigatran etexilate 63 Biochronomer 63 ATL# [002] 63 XOPENEX 63 Sufentanil 63 tramadol HCl 63 proprietary transdermal patch 63 experimental immunotherapeutics antivirals AmpligeGI mucosa resulting 63 eligen 63 sufentanil 63 pegfilgrastim 63 tezampanel 63 Elevess 63 diclofenac potassium 63 DURIN TM 63 Alvesco R 63 HGS# 63 MAGE A3 ASCI 63 prostone 63 targeted radiotherapeutic 63 Ganciclovir 63 nasal spray formulation 63 DepoDur 63 Bioral 63 Oracea ® 63 Octreolin 63 DuraSite 63 Zirgan 63 Zysolin TM 63 ENMD # 63 pen injector 63 Ketotransdel 63 Polymer Microspheres 63 dihydroergotamine 63 KL4 surfactant 63 injectable formulations 63 Cleviprex TM clevidipine 63 hydrochloride tablets 63 topical dermatology 63 Nektar PEGylation technology 63 omega interferon 63 DAVANAT 62 PNP inhibitor 62 OMNARIS 62 Oral NKTR 62 sevelamer carbonate 62 EXALGO 62 oral transdermal 62 IONSYS TM 62 HuLuc# 62 Hydrelle 62 GLASSIA 62 granisetron formulated 62 Methylnaltrexone 62 Granisetron 62 Captisol Enabled 62 Nektar proprietary 62 Anturol TM 62 orally disintegrating tablet ODT 62 DiLA2 62 Xencor XmAb 62 transdermal patch 62 Vfend 62 ARIKACE ™ 62 AzaSite Plus 62 punctal plugs 62 DexaSite 62 amphotericin B 62 diclofenac sodium 62 morphine sulfate extended 62 selective adenosine 62 generation purine nucleoside 62 Nebido 62 AstraZeneca Symbicort 62 esomeprazole Nexium 62 Dyloject TM 62 oral gallium 62 LibiGel ® 62 ENTEREG ® 62 Investigational eFlow Nebulizer System 62 biomodulator 62 antiplatelet agent 62 Personalized Immunotherapy 62 Fludara ® 62 BIO SET 62 Pegasys peginterferon alfa 2a 62 vinorelbine tartrate 62 Besivance 62 cidofovir 62 hPTH #-# 62 ZOMIG 62 candidate NGX 62 adipiplon 62 TRANSDUR Bupivacaine 62 intradermal delivery 62 adapalene 62 Panzem R NCD 62 Desonate 62 BioSilicon 62 TOCOSOL 62 VIAject R 62 hydrochloride capsules 62 Cotavance 62 anti thrombotic 62 BAL# [002] 62 Lipofen 62 PharmFilm R 62 Hyalgan 62 RLY# 62 naltrexone hydrochloride 62 DACH platinum 62 erlotinib Tarceva R 62 Keppra XR 62 docetaxel Taxotere R 62 INVANZ 62 mertansine 62 intradermal injection 62 topical acne 62 Linjeta ™ 62 Zorbtive TM 62 ViaDerm 62 bevacizumab Avastin ® 62 topical diclofenac 62 ulimorelin 62 Frova ® 62 REG1 62 nucleoside analogs 62 ESBA# 62 Cardene ® 62 FACTIVE R gemifloxacin 62 Saizen ® 62 faropenem 62 Esmya 62 anticancer compound 62 metaglidasen 62 GVAX cancer 62 sodium benzoate prescription 62 Ca DTPA 62 acyclovir Lauriad R 62 plasma kallikrein inhibitor 62 ospemifene 62 NUVIGIL ® 62 topically applied SEPA 62 Rapaflo 62 Aztreonam 62 INFeD ® 62 LEVAQUIN ® 62 EpiCeram R 62 ATPace 62 selective orally bioavailable 62 SYCREST 62 CINTREDEKIN BESUDOTOX 62 SinuNase ™ 62 Amlodipine Besylate 62 potent CYP#A# inhibitors 62 Sumavel DosePro 62 DETERx ™ 62 Inhalation Solution 62 ORADUR 62 Zipsor 62 pregabalin Lyrica 62 LEP ETU 62 ALVESCO ® 62 topical non steroidal 62 ocular formulation 62 busulfan 62 Ophena TM 62 nasal formulation 62 selective immunoproteasome inhibitor 62 ciprofloxacin hydrochloride 62 forodesine 62 Aloxi ® 62 R bendamustine hydrochloride 62 topical retinoid 62 Colesevelam 62 TIMERx 62 MetroGel 62 Pertuzumab 62 ATD TM gel 62 ALVESCO HFA 62 transmucosal 62 AeroLEF TM 62 VANOS TM 62 oral rivaroxaban 62 Liposomal 62 radiation sensitizer 61 Glucose RapidSpray 61 mesylate tablets 61 oxymorphone ER 61 BioVant 61 Navelbine ® 61 PrevOnco 61 cyclobenzaprine hydrochloride extended 61 PROMUS Element Stent 61 risedronate sodium tablets 61 ciclesonide 61 MP4 molecule 61 treat male hypogonadism 61 cromolyn sodium 61 Extina 61 Xeloda ® 61 TREDAPTIVE 61 Emollient Foam 61 Budesonide 61 Cerashield 61 trazodone hydrochloride 61 Captisol 61 Sanctura XR 61 ganetespib 61 Traficet EN 61 molecular imaging radiopharmaceutical 61 IntelGenx proprietary 61 rHuPH# enzyme 61 EXPAREL ™ 61 Itraconazole 61 REPRONEX ® menotropins 61 aerosol formulation 61 Nanobody ® 61 oxybutynin 61 Tilidine 61 oral formulations 61 mucoadhesive 61 sorafenib Nexavar 61 Resten NG 61 FACTIVE tablets 61 DuraSite ® 61 rHuPH# recombinant human 61 XTEN 61 sd rxRNA 61 betamethasone dipropionate 61 Bioral Amphotericin B. 61 Ventavis ® 61 AAG geldanamycin analog 61 Rylomine 61 BeneFIX 61 NovaBay Aganocide compounds 61 Ketotransdel TM 61 buccal tablet 61 pitavastatin 61 pegylated interferons 61 ruxolitinib 61 antiepileptics 61 MediVas 61 proprietary DuraSite ® 61 GTC recombinant human 61 topical ocular 61 Cellegesic 61 tamsulosin hydrochloride 61 Abbokinase 61 casopitant 61 NitroMist TM 61 emulsion formulation 61 Ophena 61 carbidopa levodopa 61 Iluvien ® 61 Q#IR 61 OMS#HP 61 NEXTERONE 61 dermal patch 61 Toctino ® alitretinoin 61 cytotoxics 61 QuadraSphere 61 XP #L 61 metformin HCl 61 Factor Xa inhibitor 61 TOCOSOL Camptothecin 61 arsenic trioxide injection 61 Heparins 61 inhalation aerosol 61 Duromist ™ 61 herpetic keratitis 61 FOLOTYN ® 61 Pazopanib 61 BioSilicon TM 61 Trobalt 61 long acting muscarinic 61 arsenic trioxide ATO 61 Evamist TM 61 topical NSAID 61 Vascular Wrap TM 61 Clonicel 61 Surgical Sealant 61 DOS# 61 ATD Gel 61 candidate iSONEP TM 61 SOLODYN 61 topical gel 61 rosiglitazone maleate 61 besylate 61 vaginal lidocaine 61 eTag assays 61 HFA MDI 61 parenterally administered 61 AMRIX R 61 AZILECT ® 61 Nascobal R 61 Promist 61 NasalFent 61 antiretroviral medicinal 61 sorafenib tablets 61 echinocandin 61 BiDil XR 61 Vimpat R 61 Oxiplex 61 oxycodone acetaminophen 61 Aversion r Technology 61 DepoDur TM 61 Nutra Pharma wholly owned 61 FOLFOX6 chemotherapy regimen 61 Tekamlo 61 Emend 61 THR beta agonist 61 lidocaine hydrochloride monohydrate powder 61 BUPHENYL R 61 OmniWave 61 NMDA antagonist 61 HepaGam B 61 Fenoglide 61 Exforge HCT 61 platinum chemotherapeutic 61 SyncroDose TM 61 LIVALO 61 lenalidomide dexamethasone 61 Urea Cycle Disorder 61 Medarex UltiMAb R 61 OROS ® 61 XP# XP# 61 Opterone R 61 GIPET 61 BrachySil 61 dispersible tablet 61 DYSPORT 61 Surfaxin LS 61 transdermally 61 opioid induced bowel dysfunction 61 ALN TTR# 61 amikacin 61 Nascobal 61 OMS# 61 proprietary PEGylation 61 amifostine 61 QUADRAMET R 61 Zemiva TM 61 SOLODYN R 61 TAFA# 61 paclitaxel Taxol 61 Preclinical studies suggest 61 BYETTA ® 61 Elagolix 61 situ gelling 61 Etoposide 61 zafirlukast 61 LNP formulations 61 bioabsorbable polymer 61 Octreotide 61 hypervascular tumors 61 Locked Nucleic Acid 61 GelVac TM 61 Nivestim 61 FENTORA 61 BEMA TM 61 EP #R 61 Eligen R Technology 61 quinolone 61 mesalamine 61 Mitoxantrone 61 nebulized formoterol fumarate 61 Xolegel 61 Myolimus 61 levalbuterol 61 Captisol enabled 61 Entereg R 61 PecFent 61 PerClot 61 topical dermatological products 61 mesylate 61 SIMCOR 61 investigational transdermal 61 OraDisc 61 Brimonidine 61 acne impetigo 61 Lumacan 61 aripiprazole Abilify 61 stable nucleic acid 61 INOmax 61 AMITIZA ® 61 PharmFilm 61 KNS # 61 etanercept Enbrel 60 XmAb ™ 60 Soliris eculizumab 60 TRANSDUR ® 60 LPM TM 60 levoleucovorin 60 Zolpimist 60 JAK inhibitor 60 Losartan Potassium 60 ONCASPAR 60 anti amnesic 60 Tezampanel 60 VALSTAR 60 Gonal f R 60 Cardio Vascu Grow 60 antitussive 60 HYLENEX recombinant 60 Medoxomil 60 CyDex Captisol 60 injectable gel 60 Rythmol SR 60 Release Tablets 60 Mg Usa 60 Cobalamin TM mediated 60 NitroMist 60 ABILIFY R 60 macrolide antibiotics 60 Fenofibrate 60 Pegasys ® 60 Fosphenytoin 60 COLAZAL R 60 ELADUR 60 Sporanox 60 Intravenous Human 60 Amrix 60 Zavesca R 60 selective estrogen receptor modulator 60 Actonel ® 60 Microcyn Technology platform 60 Lamictal ODT 60 hormone LHRH antagonist 60 GEM OS2 60 acting injectable formulation 60 DepoFoam 60 IV Busulfex 60 PARI eFlow 60 SPRIX ® 60 LEVAQUIN 60 azelastine 60 TLR9 agonist 60 ROZEREM TM 60 piperacillin 60 zidovudine AZT 60 liposome encapsulated 60 molecular chaperone regulation 60 trospium 60 LEUKINE 60 R bisoprolol Euthyrox 60 CoFactor 60 OTCBB HXBM developer 60 Xcytrin R 60 zaleplon 60 Oracea TM 60 immunotherapies 2A/Furin 60 Celadrin R 60 immune modulatory 60 Alinia 60 gel formulation 60 Relivar 60 SIR Spheres 60 Kepivance 60 INTEGRILIN 60 SonoPrep 60 ZYFLO R 60 candidate deforolimus 60 drug ISA# 60 lenalidomide Revlimid ® 60 MEK inhibitors 60 APL # 60 Teysuno 60 lucinactant 60 AMRIX 60 Pliaglis 60 Company TAIFUN R 60 Panzem R 60 Cetirizine 60 EvaMist TM 60 esomeprazole magnesium 60 ACTIQ ® 60 Anturol ® 60 1mg tablets 60 Spiegelmer ® 60 endothelin antagonist 60 DU #b 60 Advanced Transdermal Delivery 60 investigational humanized monoclonal antibody 60 Vaxfectin TM adjuvant 60 FOSAMAX PLUS D 60 nasal powder 60 Helixate FS 60 AEGR 60 VAPRISOL 60 Dalbavancin 60 commercialize conjugates consisting 60 soft gelatin capsule 60 calcipotriene 60 novel prodrug 60 XOPENEX Inhalation Solution 60 PrevOnco ™ 60 Irinotecan 60 hyaluronidase enzyme 60 Delivery System NTDDS 60 oral anticoagulant 60 CBLC# 60 Glumetza TM 60 Zemplar 60 Visicol 60 ELIQUIS 60 Anturol 60 treat refractory angina 60 Piperacillin 60 torezolid phosphate 60 FUSILEV ® 60 Azedra ™ 60 Atrigel 60 Lauriad R 60 Testim R 60 antifungal agent 60 acitretin 60 Ciclesonide 60 pan HDAC inhibitor 60 OsmoPrep 60 Alair System 60 Fleximer 60 Axid 60 sublingual formulation 60 Nexavar ® 60 HuMax 60 ceftazidime 60 erlotinib Tarceva ® 60 Cethrin R 60 Relieva 60 SANVAR 60 cyclophilin inhibitor 60 Sumatriptan 60 coronary stent merged 60 docetaxel Taxotere 60 Pruvel 60 somatostatin analogue 60 apomorphine 60 Initiate Clinical Trial 60 CG# [003] 60 Migranal 60 Intermezzo ® zolpidem tartrate 60 HuMax EGFr 60 Altastaph 60 NGX# 60 Hydrochloride 60 TM Aganocide 60 Formoterol 60 dexlansoprazole 60 doxercalciferol 60 ACUROX 60 fluvoxamine maleate 60 evaluating tivozanib 60 sodium sulfate sodium chloride 60 tinidazole 60 sapropterin dihydrochloride Tablets 60 Oracea R 60 ACUROX R 60 tezampanel NGX# 60 palonosetron 60 Dapagliflozin 60 granulated mesalamine 60 DORIBAX 60 apomorphine hydrochloride 60 transdermal patches 60 thrombolytic agent 60 EXPAREL TM 60 rHuPH# 60 xanthine oxidase inhibitor 60 orally dosed 60 AMEVIVE 60 Lysteda 60 platelet inhibitor 60 PORxin TM 60 Tarceva TM 60 IMA# 60 stent coating 60 Panzem NCD 60 Carvedilol 60 targeting Inflammatory Bowel 60 Degarelix 60 Elestrin TM 60 transfection reagents 60 gel formulations 60 oral antiviral 60 Nanobody 60 Tazorac 60 enoxaparin sodium 60 small molecule PEGylation 60 Belerofon 60 reformulates existing FDA 60 DXL TM 60 topically applied 60 Pafuramidine 60 YONDELIS 60 glycopyrrolate 60 CAPHOSOL 60 pharmacokinetic interactions 60 prescribed proton pump 60 EMBEDA ™ 60 incyclinide 60 CobaCyte 60 ZOLINZA 60 LE SN# 60 Rebif ® 60 antiemetics 60 rasagiline tablets 60 virus HCV protease inhibitor 60 therapeutic radiopharmaceuticals 60 Zemiva ™ 60 HCV protease inhibitors 60 Bendamustine 60 histone deacetylase inhibitor 60 Orally Disintegrating Tablets 60 anti infective therapies 60 Radix Isatidis Dispersible Tablets 60 drug zotarolimus 60 Zoraxel TM 60 CANCIDAS 60 clonidine hydrochloride 60 SERMs 60 RELISTOR ® 60 Zegerid OTC 60 XYZAL R 60 Salmeterol 60 OLEPTRO 60 ACTIQ 60 Embosphere Microspheres 60 AstraZeneca Toprol XL 60 Clolar ® 60 VersaFilm drug 60 topical gel formulation 60 VaxImmune 60 tablet formulation 60 sublingual tablet 60 TriGrid ™ 60 USL# 60 Tamibarotene 60 RNAi compounds 60 Adnectin 60 TLR agonists 60 juvenile chondrocytes 60 VIAdel TM technology 60 LidoSite 60 INVIRASE 60 Alferon N 59 Revimmune 59 subcutaneous implant 59 RADIESSE R 59 Prilosec omeprazole 59 Phospha E 59 Soriatane R 59 Multimeric 59 Bioral ® 59 antiemetic 59 oral picoplatin 59 leukotriene receptor antagonist 59 infusional 5-FU/LV 59 opioid fentanyl 59 personalized immunotherapy 59 Intravail ® 59 Vidaza R 59 Augment TM 59 Loceryl ® 59 tenofovir TDF 59 liver resection surgeries 59 TYSABRI natalizumab 59 injectable formulation 59 pegylated alpha interferon 59 MyVax R 59 mycophenolate mofetil 59 MNTX 59 HCl Tablets 59 Fodosine 59 IN.PACT Falcon 59 Bicalutamide 59 timolol maleate 59 Survivin antagonist 59 NAVISTAR R 59 Efudex 59 dSLIM 59 Moxifloxacin 59 antiangiogenic agents 59 AZILECT R 59 SUMAVEL DosePro 59 Fluticasone 59 CCX# 59 Ventavis 59 Hyphanox 59 Combunox 59 BROVANA 59 Kristalose R 59 dasatinib Sprycel 59 alvimopan 59 dry powder inhaler 59 RECOTHROM ® 59 Elan NanoCrystal 59 dosing frequency 59 Zn DTPA 59 treat facial wrinkles 59 HydroFix 59 aztreonam 59 tazarotene 59 Filgrastim 59 delivers sumatriptan 59 Sitagliptin 59 Chrysalin 59 miconazole 59 inhalation powder 59 GelVac 59 Oxaliplatin Injection 59 tizanidine hydrochloride 59 indinavir Crixivan 59 rhIGF-I/rhIGFBP-3 59 thalidomide Thalomid 59 PDX pralatrexate 59 small molecule thrombopoietin 59 CDP# 59 Exelixis compounds 59 Striant 59 MYOBLOC 59 fentanyl citrate 59 lamivudine zidovudine 59 IoGen 59 Cefazolin 59 Xyfid TM 59 VivaGel ™ 59 calcitonin 59 Icatibant 59 Tyrima 59 treat dysmenorrhea 59 intravenous acetaminophen 59 markets HP Acthar 59 corticotropin injection 59 EMSAM 59 Thrombin topical Recombinant 59 Topical Solution 59 Microspheres 59 FDA APPROVES 59 proprietary encapsulation 59 Neuromodulation System 59 candidate TNFerade biologic 59 Amnesteem 59 luliconazole 59 Oral Spray 59 Initiates Enrollment 59 Gelnique 59 eprotirome 59 balsalazide disodium 59 JZP 59 SPL# Gel vaginal microbicide 59 GelSite R 59 OLUX 59 CytoSorb 59 ProLindac TM 59 therapy Atrigel R 59 long acting bronchodilator 59 SGLT2 inhibitors 59 HMG CoA reductase inhibitors 59 opiate analgesic 59 interferon alfa 2b 59 PGL# 59 NanoCrystal ® technology 59 Renvela ® 59 Aplenzin 59 Differin ® 59 Indomethacin 59 human microdosing 59 abacavir sulfate lamivudine 59 Onalta 59 ALVESCO R 59 aerosolized AAT 59 include PLX IBD 59 BUPHENYL R sodium phenylbutyrate 59 GAMMAGARD LIQUID 59 RX ACCULINK 59 econazole 59 bioerodible 59 Transdel TM platform 59 Chemophase 59 MEVACOR 59 Fortigel 59 Targeted Chemotherapy 59 sapropterin dihydrochloride 59 HP Acthar R 59 ARIKACE 59 Clindesse 59 fesoterodine 59 BrachySil TM 59 Combination therapy 59 Rocuronium 59 ZYFLO CR 59 Oral Controlled 59 ELADUR TM 59 SEPET TM 59 Stedivaze 59 SMaRT ™ 59 Voltaren Gel 59 Anidulafungin 59 Cinnechol 59 NUEDEXTA ™ 59 synthetic retinoid 59 Eraxis 59 thymalfasin 59 Plenaxis TM 59 trodusquemine 59 ClearPath HDR 59 GelStat Migraine 59 angiotensin receptor blocker ARB 59 PSN# [001] 59 metformin sulfonylurea 59 nasally delivered 59 OncoGel 59 Enjuvia 59 losartan potassium 59 Aphthasol R 59 maleate 59 Clindamycin 59 GelSite R polymer 59 embolotherapy 59 direct thrombin inhibitors