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(Click for frequent words.) 68 miR #a [001] 68 siRNAs targeting 67 miR #a [002] 67 anti miRs targeting 66 RNA antagonist 66 PPARg 65 CCR1 65 HIF 1α 65 oral JAK1 65 5 HT2A serotonin 64 HepG2 cells 64 endogenous ligands 64 Anticalins R 64 TRAIL Receptor 64 selective inhibition 64 GPI anchored 64 vivo potency 64 microRNA miR 64 Granulocyte Colony Stimulating Factor 64 antagomirs 64 tumor antigen 63 thromboxane A2 63 amyloidogenic 63 protein tyrosine phosphatases 63 4E BP1 63 CCX# 63 mutated K ras 63 TRAIL induced apoptosis 63 mGluR5 antagonist 63 Factor Receptor 63 activin 63 biologic therapeutics 63 Eg5 63 antitumor efficacy 63 Upregulation 63 glycosylation profile 63 splice variants 63 pharmacodynamic parameters 62 miR #b [002] 62 anti CD3 62 effector function 62 c MYC 62 Janus kinase 62 TLR9 agonists 62 Clusterin 62 Tß4 62 humanized monoclonal antibodies 62 microglial activation 62 tumorigenicity 62 FGFR4 62 neuroprotective properties 62 cisplatin resistant 62 mda 7 62 Epidermal Growth Factor Receptor 62 HDAC enzymes 62 K ras mutations 62 cytostatic 62 pleiotropic 62 mTOR inhibition 62 Neuropeptide Y 62 isotypes 62 HSP# inhibitors 62 novel VDA molecule 62 FLT3 62 chemokine receptor 62 Anticalins ® 62 AT1R 62 Janus Kinase 62 enzyme inhibitors 62 ABCB1 62 immunotoxin 62 protein tyrosine phosphatase 1B 62 Flt3 62 immunoregulatory 62 mTOR inhibitors 62 HIF 1alpha 62 antiproliferative effects 62 uPAR 62 antisense inhibition 61 microtubule inhibitor 61 JAK3 61 carcinoembryonic antigen 61 neurite outgrowth 61 TÎ ² 4 61 GPx 61 cyclin dependent kinase inhibitor 61 histone deacetylases 61 serine threonine 61 effector functions 61 VEGF receptor 61 peptide antigens 61 HMGCR 61 eIF 4E 61 chemopreventive agents 61 interferon lambda 61 pathophysiological effects 61 proteins peptides 61 ENMD # 61 nAChRs 61 heparanase 61 hepatoma 61 NS5A 61 galectins 61 pro angiogenic 61 ALK inhibitor 61 antisense oligonucleotides 61 antitumor effects 61 small molecule tyrosine 61 IL #p# 61 TGR5 61 reverse transcriptase inhibitors 61 PPARγ 61 small molecule activators 61 EGFR HER2 61 PDGFR 61 rxRNA 61 CYT# potent vascular disrupting 61 intranasal delivery 61 LRAT 61 VEGF receptors 61 ERK1 2 61 dihydrofolate reductase 61 protein kinase C 61 constitutively expressed 61 XL# inhibits 61 c myb 61 GSK3B 61 A3 adenosine receptor 61 peptibody 61 microRNAs miR 61 IFN g 61 annexin 61 potent inhibition 61 antisense molecules 61 Interferon Beta 61 ghrelin receptor 61 cyclooxygenase 61 TSP1 61 KLF4 61 glucose transporter 61 bFGF 61 cMET 61 HER2 expression 61 Cdc7 61 HDAC6 61 superoxide dismutase 61 neuronal nicotinic receptors NNRs 61 targeting CD# 61 telomerase inhibitor 61 microRNA #b 61 histone deacetylase inhibitor 61 Estrogen Receptor 61 cyclophilin inhibitor 60 FBPase 60 aggrecan 60 Fibroblast Growth Factor Receptor 60 novel peptide 60 cytokine receptor 60 noncoding RNAs 60 Wnt beta catenin 60 ERK signaling 60 5 HT4 receptor 60 eotaxin 60 tumor necrosis 60 AMACR 60 cleavable linker 60 stem cell pluripotency 60 splice variant 60 GSOs 60 cyclin E 60 inhibitory effects 60 #beta HSD1 60 sequence homology 60 cationic lipid 60 OGG1 60 immunostimulatory effects 60 selectively inhibited 60 chemopreventive agent 60 reversible inhibitor 60 TRAIL receptor 60 VEGF expression 60 Angiotensin converting enzyme 60 inhibiting COX 60 HER3 60 preclinical efficacy 60 norepinephrine reuptake inhibition 60 RRM1 60 Preclinical studies suggest 60 eIF4E 60 Galectin 60 rBChE 60 CCR2 60 antimitotic 60 Aurora kinase 60 liposome encapsulated 60 transgene expression 60 Jhdm2a 60 nanomolar 60 CB2 receptor 60 MT1 MMP 60 acetylcholine receptor 60 acyltransferase 60 ORFs 60 DGAT 60 5 HT2C receptor 60 phosphate S1P 60 androgen receptor AR 60 molecular biomarkers 60 glutamyl 60 PI3K Akt 60 p# INK4a 60 rRNA 60 immunoregulation 60 pyrimidines 60 busulfan 60 agonist compounds 60 Parathyroid Hormone 60 siRNA therapeutics 60 CEACAM1 60 prostanoid 60 interferon IFN 60 RAF kinase VEGFR 60 lipid nanoparticles 60 transthyretin 60 MetAP2 60 KIAA# 60 trastuzumab Herceptin ® 60 mediated inhibition 60 inhibitor COX 60 ncRNA 60 virus AAV 60 selectively inhibit 60 NR2B subunit 60 neuroblastoma tumors 60 orally bioavailable mimics 60 Th2 cytokines 60 BRAF kinase 60 anti angiogenic agents 60 granzyme B 60 nucleosides 60 LNP formulations 60 ERK pathway 60 HER2 receptor 60 fusion enhancers 60 N cadherin 60 molecular determinants 60 mGluR2 NAM 60 short hairpin RNAs 60 Akt signaling 59 Aurora Kinase 59 PC# cells 59 TLE3 59 rxRNA compounds 59 unconjugated 59 cell adhesion molecule 59 mTOR mammalian target 59 prostaglandin synthesis 59 replicase 59 siRNA conjugates 59 p# activation 59 PTHrP 59 isoenzymes 59 somatostatin 59 antiangiogenic agents 59 p# Shc 59 SIRT1 activators 59 tumor antigens 59 DiLA2 59 tumor suppressor PTEN 59 vitro cytotoxicity 59 TGF β 59 MEK ERK 59 alkylating agent 59 colorectal tumor 59 tryptase 59 chromatin structure 59 chimeric monoclonal antibody 59 SIRT2 59 poly ADP ribose polymerase 59 M2 subunit 59 pharmacodynamic markers 59 cDNAs 59 BEXXAR Therapeutic Regimen 59 ANGPTL4 59 VEGF inhibitors 59 MAPK pathway 59 dAbs 59 thymidylate synthase TS 59 HCV replication 59 globin genes 59 survivin 59 sd rxRNA compounds 59 thapsigargin 59 peroxisomal 59 peptide fragments 59 selective agonists 59 anticancer therapeutics 59 murine model 59 EGF receptor 59 cholesteryl ester transfer 59 WT1 59 Her-2/neu 59 MTHFR 59 cytoprotective 59 Protein Kinase C 59 MEK inhibitors 59 small molecule agonists 59 immunostimulatory 59 therapeutically relevant 59 histone deacetylase 59 delta isoform 59 mutant BRAF 59 LRP5 59 NF kB pathway 59 bryostatin 59 Tie2 59 ARRY # 59 glucocorticoid receptors 59 Chemokine Receptor 59 compound AEZS 59 siRNA sequences 59 Immunomodulatory 59 MCF7 59 antisense compounds 59 lactate dehydrogenase 59 PKCi 59 cytochrome P 59 TLR8 59 missense mutations 59 Histone 59 GLI1 59 IGF1R 59 MGd 59 E#F# 59 DHFR 59 glycolipids 59 HER1 59 nicotinic acetylcholine receptor 59 chemically modified siRNA 59 ACC2 59 retinoic acid receptor 59 glutamic acid decarboxylase 59 pharmacodynamic properties 59 orally administered inhibitor 59 nanocarrier 59 Ii Key 59 pancreatic islet 59 hedgehog pathway 59 idiotype protein 59 MicroRNA 59 Kinoid 59 Drosha 59 GSTP1 59 miRNA expression 59 HER2 HER2 59 FGFR 59 hTERT 59 mimetics 59 NKX#.# 59 syngeneic 59 mRNA transcripts 59 Genotypes 59 p# alpha [001] 59 KSP inhibitor 59 Interferon alpha 59 TRPV1 agonist 59 FasL 59 lymphangiogenesis 59 Syk 59 PI3K/mTOR 59 cytokine receptors 59 R roscovitine 59 uricase 59 Akt activation 59 ALN TTR 59 IFNs 59 Systemic Delivery 59 S#P# 59 M1 muscarinic 59 antisense oligonucleotide 59 pan HDAC inhibitor 59 PDE#A 59 inverse agonist 59 selective inhibitors 59 soluble CD# 59 anionic backbone 59 TMEM#B 59 TGF alpha 59 estrogen receptor beta 59 kappa B 59 sd rxRNA 59 Wnt signaling pathway 59 IGF IR 59 Overexpression 58 targeting PCSK9 58 nucleotide analog 58 phosphoprotein 58 antiepileptics 58 Deforolimus 58 Interferon gamma 58 P selectin 58 GCase 58 Liposomal 58 anaplastic lymphoma kinase ALK 58 SCD1 58 monoclonal antibody mAb 58 RANTES 58 histone deacetylase inhibitors 58 HCV protease inhibitors 58 Fas ligand 58 biologic pathway 58 adipogenic 58 CDK inhibitor 58 JAK2 inhibitor 58 TGF ß 58 Sym# 58 microtubule targeting 58 Antiangiogenic 58 gp# protein [002] 58 gene amplification 58 Monoclonal Antibody 58 c MET 58 Aptamer 58 histone deacetylase HDAC 58 miRs 58 CDK4 58 Recombinant Human 58 BChE 58 PKC delta 58 protein tyrosine phosphatase 58 histologies 58 humanized monoclonal 58 parthenolide 58 substrate specificity 58 neurotrophic factor 58 beta1 integrin 58 lysosomal 58 Anticalin ® 58 Symadex 58 IFN gamma 58 adipokines 58 CCR9 58 RNA sequences 58 HepDirect prodrug 58 vimentin 58 factor HGF 58 lymphomas leukemias 58 xenograft models 58 Squalamine 58 combinability 58 metalloproteinase 58 sphingolipid 58 V#F mutation 58 peroxisome proliferator activated 58 Reports Preclinical Data 58 TLR9 agonist 58 therapeutic peptide 58 depsipeptide 58 liposomal formulation 58 metabolomic profiles 58 peroxidase 58 Shp2 58 vascular disrupting agents 58 Solorel TM 58 flavopiridol 58 Tissue Factor 58 Nanobodies 58 downregulates 58 vinblastine 58 inhibit viral replication 58 5 lipoxygenase 58 physico chemical properties 58 epithelial tumors 58 isoform selective 58 IL 1ß 58 BRAF mutant 58 Rap1 58 IGFBP 3 58 triphosphate 58 anti CD# antibodies 58 cytokines IL 58 potent antitumor activity 58 NMDA antagonists 58 HER2 ErbB2 58 DNA intercalator 58 developmental neurotoxicity 58 antiapoptotic 58 SPINK1 58 downregulation 58 Signaling Pathway 58 mRNA expression 58 tumor specific antigen 58 Thrombin 58 beta globin gene 58 MUC1 58 tubulin inhibitor 58 antisense inhibitors 58 pRb 58 Transmembrane 58 tyrosine phosphorylation 58 differential gene expression 58 intracellular uptake 58 virulence genes 58 Antisense 58 SNALP formulations 58 lipidoid 58 aurora kinase inhibitor 58 ESBA# 58 anticancer therapies 58 adipocyte 58 Tumor Necrosis Factor 58 topical formulations 58 ADAMTS# 58 selective modulator 58 mRNA splicing 58 FUS1 58 radiosensitivity 58 HIF 1a 58 oxidative stress inducer 58 proapoptotic 58 Pgp 58 peptides proteins 58 FGFR2 58 RNAi therapeutic targeting 58 immunohistochemical staining 58 Fibroblast 58 PI3K signaling 58 #beta HSD 1 58 neuropilin 58 Rigel R# 58 myelofibrosis polycythemia vera 58 pyrimidine 58 Oligonucleotides 58 coding genes 58 IFN α 58 nutlin 58 neurotrophic factors 58 sGC 58 HER2 neu 58 Anti Tumor 58 NFKBIA 58 antiandrogens 58 DNA methyltransferases 58 potently inhibits 58 mRNA molecules 58 Kahalalide F 58 CYP#B# 58 potent inhibitors 58 p# MAPK 58 immunological responses 58 rxRNA ™ compounds 58 TTR gene 58 PDE4 58 redox active 58 HCV replicon 58 binding affinities 58 p#NTR 58 GRNCM1 58 nucleotide analogs 58 druggable target 58 NPRL2 58 sphingolipids 58 adenosine receptor 58 Factor VIIa 58 small molecule activator 58 NSCLC tumors 58 CCL5 58 glucokinase 58 apoE 58 IgG1 58 mechanistic insights 58 Interferon alfa 58 JAK2 enzyme 58 eicosanoid 58 hypoxia inducible factor 58 Fibroblast Growth Factor 58 Amino acid 58 CYP#A# CYP#D# 57 phosphorylated proteins 57 Xenopus embryos 57 constitutively active 57 lentiviral vectors 57 serine proteases 57 peptide conjugated 57 phosphatidylinositol 3 57 echocardiographic parameters 57 Abeta peptide 57 VIPR2 57 agonists antagonists 57 coexpression 57 NF KB 57 intestinal mucosal 57 genotypic resistance 57 β catenin 57 AAV vectors 57 AKT1 57 therapeutic monoclonal antibody 57 P#X# 57 PECAM 1 57 cytidine 57 transgenic rats 57 replicon 57 nucleic acid sequence 57 matrix metalloproteinases 57 direct thrombin inhibitors 57 PDE7 inhibitors 57 erythropoietic 57 protein secreted 57 DiLA2 platform 57 PHD2 57 integrin receptors 57 Secretase 57 azacytidine 57 PC3 cells 57 Induces Apoptosis 57 auristatin 57 EphA2 57 liposome formulation 57 ERBB2 57 thrombin receptor 57 JVRS 57 serum homocysteine 57 AKT inhibitor 57 matrix metalloproteinases MMPs 57 rxRNA TM compounds 57 TRAIL receptors 57 abnormal p# 57 serum lipid 57 GRNVAC1 57 Mg Uk 57 ascorbate 57 Dendritic cell 57 potent antitumor 57 IFN beta 57 anti angiogenic agent 57 ZFP TF 57 selective kinase inhibitor 57 liver hepatocytes 57 oral picoplatin 57 heterodimers 57 peptidomimetic 57 CDK8 57 myo inositol 57 peptide hormone 57 secretase 57 Decitabine 57 Transgenic Mice 57 cellular pathways 57 #ME# 57 cardiometabolic disorders 57 mTOR signaling 57 transcriptional repressor 57 lytic 57 Trp p8 57 LDL receptor 57 neovasculature 57 small molecule thrombopoietin 57 serotonin receptor 57 Histone Deacetylase 57 Epidermal Growth Factor 57 HMG CoA reductase 57 Activating mutations 57 Novel Oral 57 plasmid DNA vaccine 57 Cytochrome P# 57 Treg cell 57 LRP6 57 colon carcinoma 57 telomerase reverse transcriptase 57 miRNA molecules 57 telomere lengths 57 cytolytic 57 Locked Nucleic Acid LNA 57 proprietary polysaccharide 57 enzyme inhibitor 57 Poly ICLC 57 adipogenesis 57 Smac mimetic 57 tumor microenvironment 57 Subunit 57 genes encoding 57 Technosphere ® 57 Angiolix 57 Immunotherapeutic 57 HOTAIR 57 protein phosphorylation 57 antiangiogenic 57 SERMs 57 targeted antifolate 57 Cyclin D1 57 transfection efficiency 57 Nilotinib 57 antibody MT# 57 kidney urologic 57 PSMA ADC 57 KRAS oncogene 57 Small Molecule 57 rifamycin 57 p# biomarker 57 DNA glycosylase 57 LHRH antagonists 57 synthetic peptides 57 μ opioid receptor 57 Galectins 57 mitogen activated protein kinase 57 prognostic biomarker 57 BCL2 57 RNAi therapeutic targeting PCSK9 57 Myostatin 57 FGFs 57 JAK2 kinase 57 RANK Ligand 57 ERa 57 coactivator 57 Kinase Inhibitor 57 adenoviral 57 G Protein Coupled 57 protein tyrosine kinase 57 proliferative disorders 57 Degarelix 57 non nucleoside HCV 57 soluble receptor 57 Macrophage 57 EGF receptors 57 IGF 1R 57 HDAC Inhibitor 57 Notch1 57 PBMCs 57 Hypoxia Inducible Factor 57 PI3K inhibitor 57 Darinaparsin 57 CCR3 57 chromosomal regions 57 inflammatory biomarkers 57 CagA 57 Mutagenesis 57 plasmin 57 MCSP respectively 57 mutated p# 57 selectively inhibiting 57 anti apoptotic 57 5 HT1A receptor 57 cathepsins 57 Analogs 57 colorectal carcinoma 57 fosbretabulin 57 FSHR 57 novel immunotherapeutic 57 proteolytic 57 ligases 57 PI3K AKT 57 Mimetics 57 CD4 + CD# 57 SMARTICLES ® 57 Hepatocytes 57 dopamine transporter DAT 57 GAD# 57 acetylcholinesterase AChE 57 retroviral vectors 57 gastrointestinal stromal tumors GISTs 57 Plasmid DNA 57 HDAC inhibition 57 ZFN modified 57 diphosphate 57 micro RNAs 57 XL# XL# 57 N Myc 57 specific lectin receptors 57 Nedd4 57 kinase inhibition 57 aurora kinase 57 selective inhibitor 57 A. thaliana 57 peptidic 57 IAP inhibitor 57 UsiRNAs 57 methylation markers 57 ERK phosphorylation 57 costimulation 57 proteasome inhibitor 57 dsRNA 57 TNFa 57 NS#/#A protease 57 SOCS3 57 TLR agonists 57 molecule therapeutics 57 multitargeted 57 p# mitogen activated 57 accumulate preferentially 57 lipid particles 57 overexpress 57 PDGF receptor 57 orexin receptors 57 glycolipid 57 OCT4 57 phosphatases 56 polyclonal antibody 56 dose proportional pharmacokinetics 56 DGAT1 56 nonnucleoside reverse transcriptase inhibitors 56 allergic airway inflammation 56 NFκB 56 EGFR signaling 56 CHD5 56 mevalonate 56 metabolic parameters 56 mRNA sequences 56 enkephalin 56 MAPK signaling pathway 56 alpha#beta# integrin 56 potently inhibit 56 Temsirolimus 56 Supplementary Table 56 hypermethylated 56 murine models 56 Talabostat 56 isotype 56 Mucosal 56 colonic mucosa 56 Receptor Antagonists 56 Kinases 56 co stimulatory molecules 56 Nanobodies ® 56 matrix metalloproteases 56 histone modifications 56 hERG 56 cytotoxic agents 56 Antisense Oligonucleotides 56 histone H3 56 pharmacokinetic PK profile 56 Onconase 56 pharmacological inhibition 56 nucleoside analog 56 TAp# 56 selective antagonist 56 folate receptor 56 serum concentrations 56 Anavex #-# 56 thyroid hormone receptor 56 caveolin 1 56 pamidronate 56 intracellular proteins 56 HER2/neu 56 adult mesenchymal stem 56 TLR antagonists 56 dasatinib Sprycel 56 Cytotoxic T 56 morpholino 56 hexose 56 ZFP Therapeutic TM 56 uM 56 TPMT 56 antitumor immunity 56 interleukin IL -# 56 radiolabeled monoclonal antibody 56 viral kinetics 56 PGC 1α 56 tkRNAi 56 ON #.Na 56 bone marrow stromal cells 56 Aldosterone 56 PGDH 56 bronchial epithelial cells 56 PI3K inhibitors 56 unmutated 56 Dasatinib 56 defensins 56 Anticalins 56 γ secretase 56 polyketides 56 TGF beta signaling 56 promoter methylation 56 Gleevec resistant 56 apolipoprotein AI 56 sphingosine 1 56 TNFα 56 Vidaza ® 56 tRNA synthetases 56 DLC1 56 EGFR HER 56 Prolongs Survival 56 IGFBP 56 allergenic protein 56 monoamines 56 FKBP# 56 vorinostat 56 antiangiogenesis 56 PEGylated interferon 56 inhibitory receptor 56 diagnostic biomarker 56 cyclophilin D 56 liposomal formulations 56 radiolabeled TM# 56 pancreatic lung 56 metalloprotease 56 MMP2 56 Allogeneic 56 subcellular compartments 56 CD4 + T lymphocytes 56 cytoplasmic domain 56 Foxp3 56 antidiabetic drugs 56 acid phosphatase PAP 56 oral renin inhibitor 56 antitumoral 56 Preclinical Study 56 Akt1 56 pharmacokinetic characteristics 56 AGHD 56 cytotoxicity assays 56 conventional DMARDs 56 HIF PH inhibitors 56 microRNAs miRNAs 56 overexpressing 56 antisense RNA 56 Zysolin TM 56 potent antiproliferative 56 radiolabeled antibodies 56 DermaVir 56 immune modulating 56 thymosin beta 4 56 VitiGam 56 potent cytotoxic 56 inhibiting telomerase 56 CYP# [002] 56 histone deacetylase HDAC inhibitor 56 MDR1 56 Mesenchymal 56 secreted protein 56 hormone gastrin 56 HQK 56 Leukemias 56 RAV# 56 metabolic inhibitor 56 histone modification 56 axonal degeneration 56 homodimers 56 TLR8 agonist 56 gamma tocotrienol 56 investigational humanized monoclonal antibody 56 tumor hypoxia 56 drug metabolizing enzyme 56 SGLT 56 DNA Methylation 56 TSH receptor 56 poloxamer 56 regulating gene expression 56 systemically administered 56 Enkephalin 56 Cytotoxicity 56 GMX# 56 Mesenchymal Stem Cells 56 endostatin 56 anti inflammatory cytokine 56 subunit vaccines 56 aminolevulinic acid 56 nucleolin 56 GPCR targets 56 cationic lipids 56 alpha#beta# 56 immune modulatory 56 subcutaneous immunoglobulin 56 epoetin alpha 56 NEUGENE R 56 Nat Biotechnol 56 antisense inhibitor 56 Cathepsin B 56 inhibiting tumor 56 CRLX# 56 renal tubular 56 ZFP TFs 56 Hsp# Inhibitor 56 transmembrane receptor 56 histone deacetylation 56 chemokine receptors 56 serum lipid levels 56 induced phosphorylation 56 Dendritic Cells 56 MTHFR gene 56 MEK inhibitor 56 inhibit replication 56 micro RNA 56 pharmacodynamic biomarkers 56 MAb 56 EGFR pathway 56 E. faecalis 56 SGLT2 56 ALK inhibitors 56 transcriptional activation 56 Catenin 56 synthetic retinoid 56 glycosylated 56 inhibit angiogenesis 56 JAK1 56 OHR/AVR# 56 inhibit enzymes 56 deacetylation 56 Presents Preclinical Data 56 tumor biopsies