chemotypes

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(Click for frequent words.) 63 enzymatic reactions 63 dAbs 63 glycolipids 62 phosphorylated proteins 62 physicochemical properties 62 splice variants 60 chromatin structure 60 bacterial genomes 60 RNA sequences 60 GPCR targets 60 biochemical assays 60 DNA gyrase 59 untranslated regions 59 Anticalins 59 polymersomes 59 antisense oligonucleotides 59 peptidic 59 eukaryotic genomes 59 KinomeScan 59 extracellular proteins 59 siRNA duplexes 59 short hairpin RNAs 59 chiral compounds 59 mRNA sequences 59 biosynthetic pathways 59 synthetic peptides 59 macrocycles 59 microRNA molecules 59 shRNAs 58 non coding RNA 58 tRNA synthetase 58 multiplex assay 58 miRNA molecules 58 cellulases 58 posttranslational modifications 58 nucleotide sequences 58 polyketides 58 ribosomal DNA 58 Nucleic acids 58 genetic loci 58 accurate quantitation 58 viral genomes 58 #S rRNA 58 soluble proteins 58 mRNA molecules 58 chromatin proteins 58 substrate specificity 58 p# inhibitors 58 amplicons 58 Anticalins R 58 sRNA 58 medicinal chemists 58 nanolayers 58 synthases 58 protein tyrosine phosphatases 58 nucleic acid molecules 58 druggable targets 57 genomic alterations 57 Streptomyces bacteria 57 receptor ligand 57 intergenic regions 57 ALK mutations 57 NR2B subunit 57 peptide antigens 57 replicase 57 amplicon 57 heterogeneous catalysts 57 viral proteins 57 multiprotein complex 57 cis regulatory 57 metalloenzymes 57 molecular biomarkers 57 cellular pathways 57 integrin receptors 57 peptoid 57 serine protease 57 anticancer therapeutics 57 allosteric 57 isotypes 57 macromolecular complexes 57 oligonucleotide 57 Affibody ® molecules 57 recombinant antibody 57 macromolecule 57 enzymatic pathways 57 unnatural amino acids 57 RNA splicing 57 physico chemical properties 57 enzyme inhibitors 57 antisense RNA 56 MEK inhibitors 56 recombinant antibodies 56 proteolytic 56 RGD peptide 56 ligases 56 putative biomarkers 56 histone deacetylase HDAC 56 tumor antigens 56 binding affinities 56 electrophysiological properties 56 micellar 56 isotype 56 trans splicing 56 ligand receptor 56 cellular organelles 56 multiplexed assays 56 Alu elements 56 MHC proteins 56 siRNA sequences 56 microenvironments 56 PCR primers 56 HCV replication 56 Anticalins ® 56 analytes 56 hybridoma 56 splice variant 56 ligand binding 56 methyltransferases 56 clonally 56 fluorescent probes 56 HDACs 56 Nanobodies 56 splice junctions 56 molecularly 56 microRNA molecule 56 heterogeneous catalysis 56 5 hydroxymethylcytosine 56 RNA strands 56 phosphatases 56 HipA 56 secreted proteins 56 biologic therapeutics 56 combinatorial libraries 56 cDNA libraries 56 Arabidopsis genes 56 effector protein 56 enzymatically active 56 monoclonals 56 P. furiosus 56 structural rearrangements 56 lincRNAs 56 biosynthetic enzymes 56 subcellular compartments 56 fungal genomes 56 CB1 antagonists 55 histone modifications 55 somatic mutations 55 monomeric 55 Nanobodies ® 55 protein subunits 55 heterochromatic 55 enzymatic pathway 55 noncoding RNAs 55 modifier genes 55 PI3K inhibitors 55 genomic loci 55 peptide sequences 55 TRP channels 55 porphyrin 55 glycosylated 55 novel anticancer therapies 55 molecules 55 virulence genes 55 aptamer therapeutics 55 Trichoderma 55 chiral molecules 55 TLR8 55 phage display libraries 55 metazoan 55 stereochemistry 55 intercellular signaling 55 Drosophila genome 55 proteomes 55 bisulfite sequencing 55 siRNA compounds 55 #S rRNA gene 55 KLF4 55 catalytic antibodies 55 genomic proteomic 55 filamentous fungi 55 degrading enzymes 55 dimensional nanostructures 55 CXCR4 receptor 55 PIP3 55 N glycan 55 bicyclic 55 selective antagonists 55 ErbB3 HER3 55 bilayers 55 protein isoforms 55 ligands 55 exons 55 microtissues 55 nucleases 55 recombinants 55 glycosylation profile 55 glycoside 55 MAPK pathway 55 rRNA 55 extracellular domains 55 prokaryotic 55 antigen receptors 55 siRNA therapeutic 55 Nanobodies TM 55 nucleotide sequence 55 pyrimidines 55 insoluble proteins 55 galectin 55 yeast genome 55 patterning technique 55 LSD1 55 bandgaps 55 KIAA# 55 outer membrane proteins 55 lipid vesicles 55 granzyme B 55 quantitative proteomics 55 moieties 55 molecular abnormalities 55 cathepsins 55 transmembrane proteins 55 secretory pathway 55 therapeutic monoclonal antibodies 55 effector molecules 55 breast cancer subtypes 55 coactivators 55 amino acid residues 55 analyte 55 #S subunit 55 sequence homology 55 antibacterial compounds 55 bacterial enzyme 55 nucleic acid sequence 55 polymer scaffolds 55 immunogens 55 hexamer 55 nucleosides 54 FFPE tissues 54 intergenic 54 ncRNA 54 hyperbranched polymers 54 PcG 54 Gene Ontology terms 54 n cofilin 54 humanized monoclonal antibodies 54 single stranded oligonucleotides 54 metabolite profiles 54 rxRNA compounds 54 biosynthetic pathway 54 chromosomal regions 54 neuroepithelial cells 54 NNR subtypes 54 deuterated 54 horseradish peroxidase 54 silencing RNAs 54 cyclodextrins 54 SIRT2 54 chemical reactivity 54 glutamate receptors 54 JAK#/JAK# 54 kinase inhibitors 54 gDNA 54 pyrimidine 54 transferrin receptor 54 genomically 54 biologies 54 proteasome inhibitors 54 biocatalytic processes 54 functionalization 54 carbonaceous meteorites 54 cell signaling pathways 54 drug metabolizing enzymes 54 carbonyls 54 miRNA expression 54 deacetylase inhibitors 54 PI3K/mTOR 54 oligomer 54 ADME properties 54 noncoding 54 non nucleoside 54 chromatin immunoprecipitation ChIP 54 molecularly targeted 54 pentamer 54 siRNA therapeutics 54 tumor subtypes 54 bioactive molecules 54 coding genes 54 kinase inhibition 54 multipotent stem cells 54 metabolizing enzymes 54 potent inhibitors 54 coding sequences 54 vertebrate embryos 54 nucleolar 54 HybSelect 54 prodrugs 54 amino acid substitutions 54 tRNA synthetases 54 topoisomerases 54 mammalian fatty acid 54 serum antibodies 54 heterocyclic 54 activatable 54 epithelial tissues 54 metabolomic profiles 54 ribozymes 54 carboxylic acid 54 U1 Adaptors 54 anti angiogenic drugs 54 optical biosensors 54 vacuolar 54 Arp2 3 54 histone deacetylation 54 quasispecies 54 malaria parasite genome 54 ESBA# 54 CHO K1 54 beta lactamases 54 ETBs 54 LNP formulations 54 hapten 54 Nedd4 54 novel peptide 54 microRNAs miRNAs 54 biochemical mechanisms 54 Cdc7 54 transcriptomes 54 chromatin immunoprecipitation 54 heterochromatin 54 miR #b [002] 54 lysate 54 gene deletions 54 #S rDNA 54 hydrogel nanoparticles 54 cofactors 54 homodimers 54 metabolic enzymes 54 bacterial chromosome 54 eukaryotic cells 54 carbohydrate polymers 54 gene expression assays 54 epitopes 54 proteases 54 lentiviral 54 microarray experiments 53 neurotransmitter receptor 53 metalloproteins 53 resonant frequencies 53 FSH receptor 53 ribosomal RNA rRNA 53 biotechnologically 53 enterotypes 53 aptamer 53 polyketide 53 alpha helices 53 quinone 53 efflux pump 53 lipid membrane 53 Htt 53 protease enzyme 53 PPARg 53 fatty acid biosynthesis 53 delipidation 53 aptamers 53 boron nitride nanotubes 53 asymmetric catalysis 53 epitope 53 cytotoxicity assays 53 heterojunctions 53 biological molecules 53 affinity antibodies 53 polymerase inhibitors 53 triphosphate 53 peptidomimetic 53 V3 loop 53 GSK3B 53 small molecule activators 53 viral antigens 53 proteins peptides 53 Anticalin 53 IMPDH 53 lymphoid tumors 53 kinase assay 53 redox reactions 53 prion strains 53 nanoparticle aggregates 53 aminoacyl tRNA synthetases 53 Rad# 53 proteomic analysis 53 mitochondrial membranes 53 HIV protease 53 DNA oligonucleotides 53 cDNAs 53 urothelial cells 53 receptor proteins 53 antisense molecules 53 genetic manipulations 53 bioconjugation 53 biocatalytic 53 synthetic chemists 53 patient subpopulations 53 ORFs 53 amyloid fibers 53 messenger RNA mRNA molecules 53 antagomirs 53 mammalian genomes 53 histone deacetylases 53 HCV protease inhibitors 53 bioinformatic approaches 53 chemoinformatics 53 kinase domain 53 M. pneumoniae 53 protein filaments 53 peroxidase 53 peptide ligands 53 fluorophores 53 FGFs 53 mitochondrion 53 PI3K AKT 53 microarray datasets 53 TLR agonists 53 peptoids 53 sequenced genomes 53 FUS1 53 terpenes 53 noncoding RNA 53 small molecule inhibitors 53 histone protein 53 antiviral compounds 53 paralogs 53 solubilizing 53 stilbene 53 chemically modified siRNA 53 cypin 53 metabolic pathway 53 protein ligand 53 Xenopus embryos 53 spider silks 53 RNA fragments 53 botulinum neurotoxins 53 MT1 MMP 53 membrane fusion 53 biodegradable biocompatible 53 Mass spectrometry 53 enzyme inhibitor 53 nanoprobe 53 microRNA biomarkers 53 cyclic peptides 53 fluorescently labeled 53 directed mutagenesis 53 supramolecular 53 zeolites 53 salinomycin 53 extracellular matrix proteins 53 enzyme catalysis 53 mesoporous 53 miRNA biomarkers 53 collagen molecules 53 glycopeptides 53 photosystems 53 biomolecule 53 morphogen 53 genotyping arrays 53 aggrecan 53 CRAC channel 53 tetracycline derivatives 53 non coding RNAs 53 eIF 4E 53 operons 53 rotaxanes 53 inorganic ions 53 protein kinases 53 peptides 53 homologies 53 heterogeneously 53 mutagenesis 53 de novo sequencing 53 microbial enzymes 53 therapeutically relevant 53 amyloid peptides 53 fluorogenic 53 cytotoxin 53 endonucleases 53 nanocluster 53 halloysite nanotubes 53 CB2 receptor 53 HSP# inhibitors 53 posttranslational modification 53 MSn 53 polymer nanofibers 53 gene expression microarrays 53 nanosprings 53 biomolecular interactions 53 DGGE 53 HSF1 53 adenosine receptor 53 ANGPTL4 53 Drosophila embryos 53 unconventional superconductivity 53 RNA polymerases 53 macrocyclic 53 polymer scaffold 52 RNA silencing 52 gene locus 52 bacterial toxins 52 RNA antagonist 52 inhibit angiogenesis 52 micrometer sized particles 52 amine oxidase 52 esterases 52 biotinylated 52 donor acceptor 52 conjugated polymers 52 conformers 52 mAbs 52 nanoparticulate 52 pharmacophore 52 physiochemical properties 52 intracellular pathways 52 partial agonists 52 UTRs 52 DNA demethylation 52 chemistries 52 membrane proteins 52 histocompatibility 52 virulence factors 52 PPARγ 52 immune stimulatory 52 PI3K inhibitor 52 polypeptides 52 gene rearrangement 52 Notch receptors 52 endospores 52 primate genomes 52 nanoarrays 52 bacterial ribosome 52 DNase 52 ubiquitin ligases 52 RNA synthesis 52 microarray gene expression 52 pro angiogenic 52 chloride channels 52 β galactosidase 52 Ubx 52 cationic lipids 52 lipid bilayers 52 comparative genomic analysis 52 anionic 52 ERK signaling 52 oligonucleotide arrays 52 ALK inhibitors 52 indibulin 52 transferase 52 VDAs 52 beta globin gene 52 Formic acid 52 AvalonRx R 52 serine threonine 52 ChIP seq 52 oligonucleotide microarrays 52 toxicogenomic 52 genetic modifiers 52 uncharacterized 52 massively parallel sequencing 52 fibril 52 mTOR inhibitors 52 cyto 52 polyamines 52 mechanistic insight 52 methylated DNA 52 tetramer 52 capsid proteins 52 transcriptionally active 52 mammalian organisms 52 macromolecular 52 immunofluorescence microscopy 52 ribozyme 52 GABAB receptors 52 nanomagnets 52 serine proteases 52 capsular polysaccharide 52 Vaccinia virus 52 interfacial properties 52 enantiomers 52 chemical syntheses 52 MAbs 52 enveloped viruses 52 undifferentiated stem cells 52 single celled yeast 52 immunodominant 52 histone deacetylase 52 biodegradable scaffold 52 parthenolide 52 peptide fragments 52 prokaryotic cells 52 vesicle fusion 52 meganuclease 52 antisense compounds 52 antifungal compounds 52 transduce 52 dimeric 52 ncRNAs 52 biosynthetic 52 pharmacodynamic markers 52 siRNAs targeting 52 trimer 52 TRPV4 52 ligand binding domain 52 RNA molecules 52 nanohorns 52 photosystem 52 adenoviral 52 aptamers derives 52 antibody antigen 52 genetic aberrations 52 druggable target 52 metabolomic 52 JAK2 inhibitors 52 cell nuclei 52 enolase 52 Membrane proteins 52 gamete formation 52 chemically modify 52 CDK inhibitors 52 polymeric materials 52 coexpression 52 PAK1 52 enzymes catalyze 52 alpha hydroxyl acids 52 acetylcholinesterase AChE 52 ribonucleic acids 52 AMACR 52 magnetosomes 52 small molecule agonists 52 nonlinear optical 52 var genes 52 fluorescent molecules 52 H#K#me# 52 quantitative PCR qPCR 52 Argonaute proteins 52 organometallic compounds 52 transcriptional repressor 52 compounds 52 chromosomal DNA 52 spectroscopic techniques 52 validate biomarkers 52 ChemBridge 52 microreactors 52 supramolecular structures 52 fluorescent quantum dots 52 EGF receptors 52 topoisomerase II 52 vitamin D receptors 52 messenger RNAs 52 tetramers 52 receptor molecules 52 P. putida 52 vivo potency 52 NMR spectra 52 gene duplications 52 phenotyping 52 molecular subtypes 52 liquid crystalline 52 gene loci 52 microbial genomes 52 PI3 kinase 52 mitochondrial gene 52 electrospray mass spectrometry 52 transcriptional machinery 52 targeted resequencing 52 hypericin 52 glycolipid 52 proline 52 endogenous ligand 52 extracellular matrices 52 antigenic peptide 52 hexamers 52 DHFR 52 synthetic polymers 52 photocatalysts 52 transcriptomic 52 polymorphs 52 ubiquitin ligase 52 peptide inhibitors 52 TNF receptors 52 hES cells 52 site directed mutagenesis 52 synthetic analogues 52 odorants 52 PKC isoforms 52 pre mRNA splicing 52 human leukocyte antigens 52 neuronal nicotinic receptors NNRs 52 vertebrate genomes 52 piggyBac 52 paraffin embedded tissue 52 sphingolipid 52 biophysical techniques 52 infecting organism 52 cyclization 52 dopant atoms 52 amino acid sequence 52 glycosylated proteins 52 differentially expressed proteins 52 catalytic reactions 52 RNA amplification 52 lentiviral vectors 52 RNA transcripts 52 radiolabeled antibodies 52 protein tyrosine phosphatase 52 Fibroblast Growth Factor Receptor 52 protease enzymes 52 diagnostic biomarkers 52 ImmuneY2 52 lipid rafts 52 P#s [002] 52 phosphoprotein 52 molecule 52 Phylomer ® 52 antisense inhibitors 52 mutational analysis 52 follicular dendritic cells 52 integral membrane proteins 52 endocytic 52 CellCarta R 52 molecule binds 52 cyclic peptide 51 nanoscale patterning 51 transcriptome sequencing 51 eicosanoid 51 pleiotropic effects 51 Anticalin ® 51 tubulin binding 51 mRNA transcripts 51 RNA enzymes 51 carbohydrate molecules 51 ABL1 51 missense mutations 51 biologically derived 51 thymidylate synthase TS 51 functional annotation 51 multiplex immunoassays 51 biodegradable nanoparticles 51 antitumour 51 biotransformation 51 enzyme cofactor 51 heterodimers 51 TLR9 agonists 51 TP# gene 51 pyrophosphate 51 cell lysate 51 physiologically relevant 51 JAK inhibitors 51 MMP# 51 homologs 51 nanocarrier 51 phage display 51 amyloid fibrils 51 anticoagulant reversing agent 51 Smac mimetic 51 antimitotic 51 cDNA microarray 51 ACTCellerate ™ 51 anionic backbone 51 hydrolyze 51 protein quantitation 51 peroxisomal 51 Monoclonal antibodies 51 motile cells 51 viral isolates 51 yeast mutants 51 tyrosine phosphorylation 51 mammary stem cells 51 Lactic acid bacteria 51 protein clumps 51 bioactives 51 fluorination 51 isoprenoid 51 AChE 51 clinically validated targets 51 Androgen receptor 51 DLC1 51 CD4 + T lymphocytes 51 isoenzymes 51 nano crystals 51 hydroxide ions 51 lymphoid cells 51 nanoclays 51 human proteome 51 FKBP# 51 immunoregulatory 51 prognostic markers 51 gold nanoclusters 51 cellulose hemicellulose 51 exosome 51 PI3 kinase inhibitor 51 glyco 51 protocells 51 riboswitches 51 C3 convertase 51 bioactive compound 51 magnetic nanoparticle 51 Proteobacteria 51 plasminogen 51 nanoscale phenomena 51 Carbon nanotube 51 III nitride 51 Gene Ontology 51 intracellular proteins 51 nanocomposite materials 51 ChIP chip 51 Immunohistochemical analysis 51 GPCRs 51 crystal lattices 51 Kinexus 51 fluorescent pigments 51 chloroplast genome 51 retroviral vector 51 eukaryotic 51 monodisperse 51 reverse transcriptase 51 fusion enhancers 51 rxRNA 51 humanized antibodies 51 insecticidal properties 51 transient transfection 51 experimentally validated 51 detection reagents 51 dimerization 51 BioSilicon 51 histologies 51 mammalian circadian clock 51 epithelial tumors 51 tumor biopsies 51 DNA methyltransferases 51 MEK1 51 gp# [002] 51 polymerases 51 Fc gamma receptor 51 HDAC inhibitors 51 benzimidazole 51 carbenes 51 poly dA 51 BiTE 51 biochemical pathways 51 nucleic acids proteins 51 PARP inhibitors 51 cordycepin 51 microsatellite markers 51 morphologies 51 viral genome 51 disulfide bonds 51 nanocomponents 51 oligomers 51 phenotypic traits 51 epigenetically 51 selective orally bioavailable 51 GLUT4 51 GPR# agonists 51 biocatalysts 51 Kv#.# 51 intracellular 51 heterologous 51 susceptibility loci 51 dendrimer 51 nanochannels 51 Golgi apparatus 51 chemiluminescence 51 molecules peptides 51 melanocortin receptors 51 cellulase enzymes 51 MDSCs 51 guanosine 51 Diels Alder reaction 51 CD# antibodies 51 PcG proteins 51 nanobubbles 51 infectious prion proteins 51 p#/CBP 51 bifunctional 51 inorganic compounds 51 catalytically active 51 indel 51 LT IIa 51 PDZ domain 51 glycan binding 51 EMBL scientists 51 coiled coil 51 anti miRs 51 fibronectin 51 borane 51 chromatogram 51 methylation patterns 51 cyclic AMP cAMP 51 interactome 51 biological macromolecules 51 inorganic salts 51 nanocarriers 51 TLE3 51 polymerase chain reactions 51 Pseudomonas syringae 51 xylan 51 HLAs 51 Chilkoti 51 shRNAmir 51 cytoskeletal structure 51 oligomerization 51 peptide hormones 51 epiblast stem cells 51 proteins nucleic acids 51 ACTCellerate TM 51 zebrafish Danio rerio 51 homologues 51 mediated autoimmune diseases 51 bispecific antibody 51 nanoelectronic devices 51 conserved sequences 51 beta lactam 51 ERK2 51 substituents 51 cytokine receptors 51 PI3K Akt 51 protocell 51 intracellular bacteria 51 trimeric 51 TAT Bim 51 eukaryotic organisms 51 nitrogenase 51 chemogenomics 51 transmembrane protein 51 hERG 51 DNA rearrangements 51 myosins 51 cleavable 51 secrete proteins 51 demethylase 51 condensin 51 Magnetic nanoparticles 51 Tarvacin Anti Viral 51 antibody arrays 51 siRNA mediated 51 proteins 51 T#I [002] 51 histone H4 51 epigenetic enzymes 51 neural progenitor cells 51 anticancer compounds 51 polymer gels 51 synaptogenesis 51 noncancerous cells 51 preclinically 51 membrane protein 51 indels 51 lipid nanoparticles 51 proteolytic cleavage 51 Fanconi proteins 51 Fc receptor 51 microRNA expression 51 nucleated cells 51 PKM2 51 HepDirect prodrug 51 oligomeric 51 ribonucleic acid RNA 51 electroactive 51 mass spectrometric 51 inhibitory receptors 51 NEUGENE 51 combinatorial chemistry 51 CD#b 51 BChE 51 intracellular signal transduction 51 inorganic nanoparticles 51 ATP synthase 51 microfluidic channels 51 optogenetic 51 fluorescent dye molecules 51 miRNA sequences 51 xenobiotic 51 impurity atoms 51 nicotinic receptors 51 C5a receptor 51 photosynthetic bacteria 51 tumor antigen 51 glycolytic 51 proline rich 51 transmembrane 51 micro RNA 51 colloidal nanocrystals 51 cyclins 51 telomerase inhibitor 51 resistant mutants 51 effector functions 51 PI3 K 51 Nanobody ® 51 sd rxRNA 51 nucleic 51 macromolecules 51 Smac mimetics 51 APOBEC3G

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