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(Click for frequent words.) 71 lomitapide 70 GRN# 70 midstage clinical 70 phase IIb trial 70 riociguat 70 NP2 Enkephalin 70 Phase IIb clinical trials 70 oxymorphone ER 70 forodesine 70 opioid induced bowel dysfunction 69 bicifadine 69 diabetic neuropathic pain 69 rhIGF-I/rhIGFBP-3 69 Prosaptide 69 NV1FGF 69 sitaxsentan 69 cannabinor 69 Cinquil 69 Mipomersen 68 Corlux 68 Octreolin 68 ZOLINZA 68 Fx #A 68 refractory angina 68 MAGE A3 ASCI 68 reslizumab 68 GGF2 68 KRN# 68 Cloretazine 68 phase IIb clinical 68 acute mania 68 EVIZON TM 68 Tocosol Paclitaxel 68 phase IIa clinical 68 SomatoKine 67 TELINTRA 67 refractory gout 67 Fibrillex TM 67 Pagoclone 67 Zenvia ™ 67 oxypurinol 67 eritoran 67 macitentan 67 Troxatyl 67 TASKi3 67 Phase IIB 67 Bicifadine 67 aflibercept VEGF Trap 67 YONDELIS 67 CRMD# 67 SinuNase 67 ruxolitinib 67 SNT MC# 67 dacetuzumab 67 trial evaluating PRX# 67 rEV# 67 KIACTA ™ 67 randomized Phase IIb 67 recurrent glioblastoma multiforme 67 ELACYT 67 TOCOSOL Camptothecin 67 Gattex 67 gepirone ER 67 Androxal TM 67 Phase #b/#a 67 clazosentan 67 ProSavin 67 Canvaxin 67 Telintra 67 budiodarone 67 terlipressin 67 OHR/AVR# 67 tezampanel 67 midstage trials 67 Aflibercept 67 MyVax 66 Phase IIIb clinical 66 thetreatment 66 incyclinide 66 urocortin 2 66 IL# PE#QQR 66 oral methylnaltrexone 66 Nicole Onetto MD 66 Pimavanserin 66 BrachySil TM 66 Glypromate 66 elotuzumab 66 metastatic sarcomas 66 Prestara 66 BAY #-# 66 Fibrin Pad 66 OMNARIS HFA 66 eosinophilic asthma 66 calcineurin inhibitor 66 PDE# inhibitors 66 nalbuphine ER 66 rBChE 66 HQK 66 Viprinex TM 66 diabetic gastroparesis 66 Viprinex 66 Behcet uveitis 66 Panzem R NCD 66 CINTREDEKIN BESUDOTOX 66 PRT# 66 dirucotide 66 Major Depressive Disorder MDD 66 Phase Ib study 66 Asentar 66 mertansine 66 rALLy clinical trial 66 Phase Ib II 66 alvespimycin 66 oral ridaforolimus 66 vidofludimus 66 Clonicel 66 TBC# 66 severe gastroparesis 66 Ketotransdel 66 Archexin 66 otelixizumab 66 LymphoStat B TM 66 invasive candidiasis 66 talactoferrin 66 esophageal candidiasis 66 neurogenic orthostatic hypotension 66 rufinamide 66 Dacogen injection 66 DDP# 65 ularitide 65 tafamidis 65 pertuzumab 65 Milnacipran 65 OvaRex 65 Inc. Nasdaq NLTX 65 postoperative ileus POI 65 motesanib 65 GSK# [002] 65 EFAPROXYN 65 receptor tyrosine kinase inhibitor 65 Tasimelteon 65 Vernakalant 65 Pyridorin 65 OvaRex ® MAb 65 MGd 65 Aclidinium 65 Desmoteplase 65 JAK inhibitor 65 EP #R 65 midstage clinical trial 65 methylnaltrexone 65 Phase #b/#a clinical 65 OMS#HP 65 schizophrenia CIAS 65 Cethrin R 65 Cethrin 65 ospemifene 65 Evoltra TM 65 Sulonex 65 Elocalcitol 65 Plicera 65 investigational monoclonal antibody 65 eltrombopag 65 novel oral anticoagulant 65 Cloretazine R VNP#M 65 CytoFab ™ 65 severe hypercholesterolemia 65 almorexant 65 HGS# 65 cangrelor 65 baminercept 65 faropenem medoxomil 65 velafermin 65 oral prodrug 65 sorafenib Nexavar 65 iniparib 65 edifoligide 65 HeFH 65 torezolid phosphate 65 rALLy 65 Kepivance 65 tramiprosate 65 lumiliximab 65 canakinumab 65 rolofylline 65 Aplidin 65 placebo controlled clinical 65 CEQ# 65 Itopride 65 glufosfamide 65 colorectal cancer liver metastases 65 aerosolized AAT 65 Phase IIb III 65 TLK# 65 R#/MEM # 65 Factor VIIa 65 thalidomide Thalomid 65 Fibrillex 65 chronic thromboembolic pulmonary 65 Pegloticase 65 Azedra 65 deforolimus 65 antithrombotic therapy 65 opioid induced constipation 65 INCB# [001] 65 pseudobulbar affect PBA 65 Neurodex 65 including eniluracil ADH 65 CBLC# 65 Phase 1a clinical 64 Frova ® 64 Adentri 64 Vilazodone 64 tolevamer 64 metastatic HRPC 64 cediranib 64 Cloretazine ® 64 Orencia abatacept 64 cobiprostone 64 retinal vein occlusion induced 64 axitinib 64 docetaxel Taxotere ® 64 phase IIb 64 Vorapaxar 64 GED aPC 64 Acute Radiation Syndrome ARS 64 Arcalyst 64 RhuDex ® 64 ACZ# 64 aerosolized KL4 surfactant 64 Stanate R 64 vernakalant hydrochloride 64 PRIMO CABG 64 Lixivaptan 64 Genasense ® 64 Deferiprone 64 Ataluren 64 cilengitide 64 Perforomist ™ Inhalation Solution 64 Tavocept 64 Aviptadil 64 PI3K/Akt pathway inhibitor 64 Provacel 64 ISTODAX 64 Hepatocellular Carcinoma HCC 64 CDP# 64 tezampanel NGX# 64 aflibercept 64 VAPRISOL 64 PDE4 inhibitor 64 Revlimid lenalidomide 64 RSD# oral 64 Bifeprunox 64 BRAF inhibitor 64 OMP #R# 64 catheter occlusion 64 uric acid lowering 64 Zybrestat 64 phase IIa 64 Tarceva TM 64 blood clot dissolving 64 relapsing remitting MS RRMS 64 relapsed multiple myeloma 64 AGHD 64 Dacogen decitabine 64 alvimopan 64 idiopathic thrombocytopenic purpura ITP 64 ATL# [001] 64 either acutely decompensated 64 recurrent herpes labialis 64 Phase IIb trials 64 Alimta pemetrexed 64 Benlysta belimumab 64 post operative ileus 64 PEARL SC 64 JAK2 inhibitor 64 Vidaza azacitidine 64 oral talactoferrin 64 visilizumab 64 Ceflatonin R 64 teriflunomide 64 CIPN 64 Frozen Shoulder Syndrome 64 acetonide FA 64 PXD# 64 MyVax personalized immunotherapy 64 SinuNase TM 64 Onconase 64 Abbokinase 64 maribavir 64 intravenous methylnaltrexone 64 ThGRF 64 Ceflatonin 64 RezularTM 64 Azedra TM 64 Phenoptin 64 Phase 2a trial 64 anticancer therapy 64 acute decompensated heart 64 TNF antagonist 64 adipiplon 64 rindopepimut 64 Onrigin 64 Phase Ib clinical 64 Microplasmin 64 rasagiline tablets 64 LidoPAIN SP 64 ACV1 64 ATL# [002] 64 Nebido 64 amrubicin 64 orBec 64 mapatumumab 64 Xanafide 64 Dextofisopam 64 TACI Ig 64 Proquin XR 64 Tolamba 64 lupus nephritis 64 OncoGel 64 TTF Therapy 64 postoperative ileus 64 VNP#M 64 eprotirome 63 AEGR 63 GLPG# 63 Balaglitazone 63 ocrelizumab 63 MYDICAR ® 63 ziconotide 63 sulodexide 63 Allovectin 7 63 oral antiviral 63 hylan GF 63 INxin 63 TYSABRI natalizumab 63 enzastaurin 63 eniluracil 63 symptomatic neurogenic orthostatic hypotension 63 opioid bowel dysfunction 63 apoptosis inducer 63 phase IIb study 63 Somatuline Depot 63 medically refractory 63 Tyrima 63 vaginally administered lidocaine 63 clevidipine 63 Phase 2a clinical 63 Panzem R 63 TNF inhibitor 63 TNF inhibitor therapy 63 Insegia 63 Nexavar sorafenib 63 BNC# 63 dextofisopam 63 Gaboxadol 63 oral anticancer 63 SomatoKine R 63 PPAR gamma agonist 63 Cloretazine R 63 Golimumab 63 Deforolimus 63 OvaRex R 63 AA Amyloidosis 63 vosaroxin 63 Nuvion 63 MNTX 63 neratinib 63 rFVIIa 63 glucokinase activator 63 Gleevec imatinib 63 alemtuzumab Campath 63 Egrifta 63 Oglemilast 63 Personalized Immunotherapy 63 ganetespib 63 Phase 2b study 63 PNP inhibitor 63 Cimzia TM 63 GALNS 63 Annamycin 63 intravenous cyclophosphamide 63 CTAP# Capsules 63 intranasal formulation 63 posaconazole 63 AEG# 63 AQ4N 63 ixabepilone 63 bortezomib Velcade 63 immune modulator 63 PF # [002] 63 PhG alpha 1 63 phase Ib 63 Cardio Vascu Grow 63 Candesartan 63 immune thrombocytopenic purpura ITP 63 Synavive 63 relapsed ALL 63 hypervascular tumors 63 Stedivaze 63 treat chronic sinusitis 63 briakinumab 63 Amrubicin 63 cortical stimulation 63 UPLYSO 63 teplizumab 63 Saforis 63 Morquio 63 atacicept 63 canagliflozin 63 phase III isavuconazole 63 ICA # 63 tecarfarin 63 systemically administered 63 IV Busulfex 63 GAMMAGARD 63 Omacetaxine 63 cetuximab Erbitux 63 Aggrastat ® tirofiban hydrochloride 63 ganaxolone 63 EndoTAG TM -1 63 Zingo TM 63 Pazopanib 63 Ophena TM 63 Xerecept 63 Zemplar Capsules 63 trastuzumab DM1 T DM1 63 Gemzar gemcitabine 63 TRO# 63 Bezielle 63 overactive bladder syndrome 63 midstage clinical trials 63 CytoFab 63 Myelodysplastic Syndrome MDS 63 pain palliation 63 Phase 2a clinical trials 63 Zelapar 63 bifeprunox 63 CCR9 antagonist 63 radiation sensitizer 63 Velcade bortezomib 63 BST CarGel R 63 budesonide foam 63 senicapoc 63 GLYX 63 Rezular 63 Safinamide 63 generation purine nucleoside 63 TNF alpha inhibitor 63 Posidur 63 bardoxolone 63 constipation predominant irritable bowel 63 confirmatory Phase III 63 factor Xa inhibitor 63 Civacir 63 opioid analgesia 63 fampridine SR 63 pamidronate 63 Allovectin 7 ® 63 randomized Phase 2b 63 antifibrinolytic 63 acyclovir Lauriad R 63 Muraglitazar 63 Catena ® 63 GSK# [001] 63 IPL# 63 DACH platinum 63 AZILECT R 63 Degarelix 63 oxaliplatin Eloxatin 63 steroid refractory GvHD 63 antibody MAb 63 Friedreich Ataxia FRDA 63 BEMA Buprenorphine 63 ATL/TV# 63 antifibrotic 63 dirucotide MBP# 63 brivaracetam 63 IPLEX 63 antimetabolite 63 HuMax EGFr 63 Lupuzor 63 idiopathic thrombocytopenic purpura 63 HuMax CD4 63 insulin sensitizing 63 myeloproliferative disorders 63 Diamyd ® 63 chronic myocardial ischemia 63 Zenapax 63 Rasagiline 63 Sutent sunitinib 63 Exelixis compounds 63 Panzem 63 zanolimumab 63 Protexia ® 63 phase IIb III 63 CIMZIA ™ 63 MAXY VII 63 Factor Xa inhibitor 63 verteporfin 63 davunetide intranasal AL 63 pharmacokinetic PK study 63 metastatic CRC 63 galiximab 63 choroidal vasculopathy 63 phase 2a 63 DU #b 63 SinuNase ™ 63 IPLEX TM 63 MyVax ® 63 samalizumab 63 Traficet EN 63 TNF blocker 63 abiraterone 63 docetaxel Taxotere R 63 CA9 SCAN 63 SNT-MC#/idebenone 63 Valtropin 63 Evoltra 63 Abilify aripiprazole 62 Triapine R 62 AGILECT R 62 synthetic retinoid 62 cystinosis patients 62 SYN# 62 ponatinib 62 Preos 62 Removab 62 regorafenib 62 DEB# 62 therapeutic monoclonal antibody 62 treprostinil 62 benign prostatic hypertrophy BPH 62 adalimumab Humira 62 postsurgical pain 62 gamma secretase inhibitor 62 lintuzumab SGN 62 VA# [002] 62 BrachySil ™ 62 TYZEKA 62 INTEGRILIN 62 PLX cells 62 ORENCIA R 62 xanthine oxidase inhibitor 62 novel therapeutic antibodies 62 elacytarabine 62 sunitinib malate 62 Valdoxan 62 novel histone deacetylase 62 Inc. NASDAQ NLTX 62 perampanel 62 Ixempra 62 Targretin capsules 62 pharmacologic therapies 62 drug figitumumab 62 INS# [001] 62 Hedgehog Pathway Inhibitor 62 Phase IIb trial 62 ACOMPLIA R 62 FM VP4 62 heterozygous FH 62 Romiplostim 62 Laquinimod 62 Aryplase 62 omecamtiv mecarbil 62 Proxinium TM 62 MOZOBIL 62 oral mTOR inhibitor 62 neurologic progression 62 Trofex 62 KAPVAY ™ 62 cancer neuroendocrine tumor 62 DXL# 62 tasisulam 62 RSR# 62 Pafuramidine 62 beta 1a 62 pemetrexed Alimta 62 multiple myeloma MM 62 systemic fungal infections 62 interferon beta therapy 62 erlotinib Tarceva 62 Aurexis 62 Gleevec imatinib mesylate 62 PRX # 62 PrevOnco 62 ALN VSP Phase 62 Azixa 62 lapatinib Tykerb 62 MYLOTARG 62 ozarelix 62 RhuDex 62 trial evaluating Prochymal 62 Lu AA# 62 fosbretabulin 62 EDEMA3 trial 62 CB2 selective receptor agonist 62 iroxanadine 62 ELND# 62 Alzhemed TM 62 Ketotransdel TM 62 bardoxolone methyl 62 metaglidasen 62 sodium thiosulfate STS 62 CytoFabTM 62 TRV# [001] 62 Kiacta 62 anticlotting drugs 62 EVIZON ™ 62 anagrelide 62 Kamada AAT 62 adjuvant colon cancer 62 Cx# [002] 62 ARIKACE ™ 62 oral salmon calcitonin 62 CIMZIA TM certolizumab pegol 62 AZILECT ® 62 palliative radiotherapy 62 hepatitis B vaccine Heplisav 62 systemic ALCL 62 Ceflatonin ® 62 IRX 2 62 Cerovive 62 Phase Ib IIa 62 SILENOR 62 Alequel 62 solanezumab 62 Campath ® 62 ReN# 62 Taxol paclitaxel 62 mGluR2 NAM 62 investigational therapies 62 Levetiracetam 62 refractory CLL 62 Spiegelmer ® 62 ProMune 62 Alocrest 62 Targretin 62 bowel dysfunction 62 mTOR inhibition 62 IMA# 62 triphendiol 62 NASDAQ OMER 62 thrombin inhibitor 62 Diamyd R 62 antithrombotic 62 Combidex 62 romidepsin 62 octreotide implant 62 STRIDE PD 62 OncoVEX 62 LAS# [002] 62 Wellstat 62 Mycograb 62 Hedgehog antagonist 62 ocular inflammation 62 carcinoid syndrome 62 dose escalation phase 62 relapsing remitting multiple sclerosis 62 Myocet 62 Erbitux cetuximab 62 BioNumerik 62 immunotherapeutic vaccine 62 Voraxaze 62 trodusquemine 62 immunomodulatory therapy 62 PSN# [001] 62 OncoVEX GM CSF 62 relapsed MM 62 pivotal bioequivalence 62 treat dysmenorrhea 62 MabThera rituximab 62 Phase IIa clinical 62 lipid lowering therapies 62 EOquin TM 62 Aloxi injection 62 kidney urologic 62 rilonacept 62 eculizumab therapy 62 Cancidas 62 ACTEMRA TM 62 CCR5 mAb 62 tremelimumab 62 BENLYSTA ® 62 E2F Decoy 62 Aurograb 62 tipifarnib 62 Reverset 62 Memryte 62 MEND CABG II 62 glatiramer 62 Serdaxin 62 Tykerb lapatinib 62 anidulafungin 62 somatostatin analogues 62 ticagrelor Brilinta 62 Zemiva TM 62 noninfectious uveitis 62 vemurafenib 62 Resten NG 62 MIST II 62 SEPET TM 62 R sorafenib tablets 62 blood clot dissolver 62 lucinactant 62 IV APAP 62 Arikace 62 corticosteroid dexamethasone 62 neoadjuvant setting 62 anti thrombotic 62 phase III ACCLAIM 62 EndoTAGTM 1 62 HuMax CD# 62 oral anti arrhythmic 62 ASONEP 62 Phase IIa trial 62 FROVA 62 Addrenex 62 ONCONASE R 62 hormone LHRH antagonist 62 intravenous immunoglobulin 62 opioid induced constipation OIC 62 Altastaph 62 optimal dosing regimens 62 Vimpat R 62 BEMA TM Fentanyl 62 Panzem ® 62 lintuzumab 62 LibiGel ® 62 Chrysalin 62 Fodosine 62 BLA filing 62 BRIM2 62 Inhalation Solution 62 agomelatine 62 teduglutide 62 Genz # 62 histamine dihydrochloride 62 neurogenic bladder 62 non metastatic osteosarcoma 62 modified REGENESIS Phase IIb 62 nucleotide analog 62 dose escalation clinical 62 pediatric malignancies 62 Prodarsan 62 figitumumab 62 immunomodulatory agents 62 Squalamine 62 HDL Selective Delipidation 62 Camvia 62 refractory acute myeloid 62 squalamine 62 vismodegib 62 smoldering multiple myeloma 62 Hematide ™ peginesatide 62 Adlea TM 62 oral antifungal 62 familial hypercholesterolemia FH 62 PROMACTA 62 pregabalin Lyrica 62 bevacizumab Avastin ® 62 VALSTAR 62 pouchitis 62 DPP4 62 HCD# [002] 62 telaprevir VX 62 polycythemia vera essential thrombocythemia 62 ulimorelin 62 Silodosin 62 pafuramidine 62 DPX Survivac 62 tiapamil 62 Zoraxel 62 Zarnestra 62 Tolvaptan 62 targeted radiotherapeutic 62 StemEx 62 unresectable malignant mesothelioma UMM 62 arterial thrombosis 62 calcineurin inhibitors 62 hypoparathyroidism 62 Troxatyl TM 61 PSMA ADC 61 JAK3 inhibitor 61 GLP1 agonist 61 MYDICAR 61 inhaled AAT 61 Phase 2b clinical trials 61 Symadex 61 PHX# 61 drug ISA# 61 Mirapexin 61 Amplimexon 61 leukemia AML 61 huC# DM4 61 chronic neuropathic pain 61 selective androgen receptor modulator 61 INTEGRILIN ® 61 Seliciclib 61 diarrhea predominant irritable 61 LAF# 61 MEVACOR 61 initiate Phase 1b 61 factor VIIa 61 CVBT #H 61 Enzastaurin 61 omega interferon 61 CRD5 61 PRADAXA 61 Evoltra ® 61 TNF alpha antagonist 61 brentuximab vedotin SGN 61 ELIQUIS 61 RSD# 61 etanercept Enbrel 61 Arranon 61 sargramostim 61 haematological cancers 61 Pivotal Phase III 61 opioid induced 61 mitoxantrone plus 61 ADAGIO study 61 Ophena 61 ONTAK 61 multicenter Phase II 61 Triolex 61 BRIM3 61 faropenem 61 bafetinib 61 adenosine A2A 61 superficial bladder cancer 61 Viramidine 61 dopaminergic therapy 61 AQUAVAN R 61 chronic idiopathic thrombocytopenic purpura 61 Solazed 61 zalutumumab 61 Myoblast Program 61 Urocortin 2 61 EXJADE 61 gastrointestinal mucositis 61 Cogane 61 anti CD3 antibody 61 Kynapid 61 pradefovir 61 cognitive impairment associated 61 Fabry Disease 61 Cleviprex TM clevidipine 61 lenalidomide Revlimid R 61 Clolar ® 61 Vitaxin 61 Omnitarg 61 Vectibix panitumumab 61 daptomycin 61 THALOMID 61 Dificid 61 INVEGA ® 61 AZX# 61 oral rivaroxaban 61 isavuconazole 61 INCB# [003] 61 DepoDur 61 Cotara ® 61 post herpetic neuralgia PHN 61 Sudhir Agrawal D.Phil 61 octreotide acetate 61 biliary tract cancer 61 LE DT 61 clinical pharmacology studies 61 subcutaneous methylnaltrexone 61 PDX pralatrexate 61 Promacta 61 palifermin 61 Ereska 61 varespladib 61 therapeutic regimens 61 Starlix 61 Abiraterone 61 paliperidone ER 61 investigational humanized monoclonal antibody 61 Tamibarotene 61 temsirolimus 61 interferon therapy 61 zileuton CR 61 Pirfenidone 61 induced macular edema 61 ostarine 61 FOLOTYN ® 61 diabetic kidney 61 ADVANCE PD 61 thrombolytic agent 61 Tekamlo 61 MP4OX 61 intranasal delivery 61 TMS Therapy 61 weekly subcutaneous injections 61 Denufosol 61 hour bronchodilation 61 Cethromycin 61 recurrent malignant glioma 61 AGGRASTAT R 61 Genentech Rituxan 61 Zenvia Phase III 61 Roche Actemra 61 5-fluorouracil/leucovorin 61 naronapride 61 aromatase inhibitors AIs 61 liprotamase 61 apricitabine 61 rhThrombin 61 efalizumab 61 SUTENT ® 61 Soliris eculizumab 61 oral deforolimus 61 dasatinib Sprycel 61 Actemra tocilizumab 61 Increlex ® 61 Exherin TM 61 SUCCEED trial 61 sJIA 61 Specifid 61 Huntexil 61 trastuzumab DM1 61 eculizumab 61 albiglutide 61 hereditary deficiency 61 HCV antiviral 61 hypercholesterolemic patients 61 Severe Primary IGFD 61 menadione 61 class mGluR5 inhibitor 61 PROCHYMAL 61 antiplatelet agent 61 atherothrombotic events 61 edifoligide E2F Decoy 61 Neupogen ® 61 bevacizumab Avastin 61 Begins Dosing 61 thrombolytic agents 61 Advagraf 61 Spiro Rombotis President 61 prophylactic therapy 61 pancreatic insufficiency 61 subcutaneous formulation 61 Prodarsan ® 61 Lantus insulin 61 preclinically 61 anticoagulant reversing agent 61 Potiga 61 Proellex TM 61 LEP ETU 61 inhaled treprostinil 61 RhuDex R 61 TriRima 61 nephrotoxicity 61 IMPACT DCM clinical 61 desvenlafaxine 61 Tarceva erlotinib 61 midstage studies 61 GMX# 61 EMSAM 61 successfully commercialize Iluvien 61 psoriatic arthritis PsA 61 Teriflunomide 61 Enzyme Replacement Therapy 61 UCB Cimzia 61 Xyfid TM 61 cetuximab Erbitux R 61 OZURDEX ® 61 Atrasentan 61 Zerenex 61 secondary hyperparathyroidism 61 malignant ascites 61 confirmatory clinical 61 rivaroxaban Xarelto 61 obatoclax 61 NATRECOR R 61 systemic immunosuppressive drugs 61 chronic angina 61 post menopausal osteoporosis 61 Mepact 61 Safi Bahcall Ph.D. 61 interferon ribavirin 61 Zytiga 61 CIMZIA TM 61 relapsed AML 61 painful diabetic neuropathy 61 GW# [003] 61 personalized cellular immunotherapy 61 zileuton 61 Achieves Primary Endpoint 61 telcagepant 61 tizanidine hydrochloride short 61 BYETTA exenatide injection 61 gefitinib Iressa 61 renoprotective 61 HP Acthar Gel 61 desmoteplase 61 Urocidin