Related by context. Frequent words. (Click for all words.) 68 caloric restriction 67 calorie restriction 63 insulin secretion 62 glucocorticoid 62 SIRT1 61 mitochondrial function 61 leptin 59 telomere length 59 Leptin 59 rapamycin 59 adiponectin 59 mTOR 59 signaling pathway 59 metabolic 59 metabolism 58 signaling pathways 58 molecular pathway 58 arginine 58 insulin resistance 58 molecular pathways 58 autophagy 58 glucose tolerance 58 lipid metabolism 58 serum cholesterol 57 neurogenesis 57 overexpression 57 insulin sensitivity 57 protein synthesis 57 platelet aggregation 57 thyroid hormones 57 STAT3 57 BDNF 57 PYY 56 oxidative damage 56 oxidative stress 56 metabolic processes 56 endothelial function 56 telomere 56 fat diet 56 signaling molecule 56 protein 56 amino acid 56 calcium absorption 56 endothelial dysfunction 56 curcumin 56 dietary fat 56 estrogen receptors 56 neuroendocrine 56 bone resorption 56 molecular mechanism 56 phenotype 56 TGF beta 55 inflammatory cytokines 55 aldosterone 55 glutamine 55 orexin 55 metabolic pathways 55 Akt 55 inhibitory 55 lipid levels 55 folate 55 retinoic acid 55 ghrelin 55 glucose metabolism 55 cysteine 55 carcinogenesis 55 phosphorylation 55 telomeres 55 proteins 54 AMPK 54 secretion 54 gene expression 54 cognitive function 54 enzyme 54 adipocytes 54 interferon beta 54 thyroid hormone 54 mammalian cells 54 NF kB 54 dopamine neurons 54 glutamate 54 resveratrol 54 calorie diet 54 fat diets 53 neurodegeneration 53 dietary intake 53 mRNAs 53 dysregulation 53 hormone insulin 53 glucocorticoids 53 immune responses 53 metformin 53 isoflavones 53 estrogen receptor 53 angiotensin II 53 histone 53 androgen receptor 53 tumor suppressor 53 probiotic bacteria 53 methylation 53 endothelin