Related by context. Frequent words. (Click for all words.) 65 dysregulation 64 Oxidative stress 62 Chronic inflammation 62 pathophysiological 61 carbohydrate metabolism 59 hormone imbalances 59 estrogen deficiency 59 neuroinflammation 59 HPA axis 59 neuroendocrine 59 hyperinsulinemia 59 Acid reflux 59 ADAM# 59 oncogenesis 59 endocrine glands 59 hormonal imbalances 58 COX2 58 thyroid dysfunction 58 metabolic acidosis 58 pathophysiologic 58 gluconeogenesis 58 platelet activation 58 serotonin neurotransmitter 57 inflammatory cascade 57 dysregulated 57 cholesterol metabolism 57 NADPH oxidase 57 overactivity 57 Chronic fatigue 57 neuropeptides 57 resistin 57 galanin 57 psychogenic 57 fatty acid oxidation 56 synapse formation 56 metabolic abnormalities 56 degenerative disorders 56 QT prolongation 56 hormone secreted 56 catecholamine 56 Insulin resistance 56 protein misfolding 56 fatty acid metabolism 56 developmental abnormalities 56 suppresses appetite 56 genomic instability 56 systemic inflammation 56 neurochemistry 55 GABA receptors 55 Hyperthyroidism 55 Wnt signaling pathway 55 endocannabinoid system 55 flavanoids 55 biologically plausible 55 genetic susceptibility 54 leptin resistance 54 nNOS 54 eNOS 54 hyperglycaemia 54 ketoacidosis 54 hyperparathyroidism 54 Lactose intolerance 54 fatty acid synthase 54 Periodontal disease 54 microglial cells 54 innate immune 54 estrogen receptor alpha 54 nutritional deficiency 54 thyroid hormones 54 hormonal fluctuations 54 physiological mechanisms 54 glucose homeostasis 54 catabolism 54 Pulmonary hypertension 54 act synergistically 54 innervation 54 potentially modifiable 54 Soluble fiber 54 proinflammatory cytokines 54 adrenal fatigue 53 etiologic 53 vascular abnormalities 53 vascular inflammation 53 seratonin 53 Autoimmune diseases 53 Uric acid 53 misfolding 53 incompletely understood 53 PDGFR 53 untreated sleep apnea 53 molecular underpinnings 53 polyamines 53 biochemical mechanisms 53 mitochondrial dysfunction 53 periodontal diseases 53 Prenatal exposure 53 biochemical processes 53 Sirt1 53 oestrogens 53 proinflammatory 53 cellular metabolism