druggable

Related by string. * * druggable targets . druggable target . druggable genome *

Related by context. All words. (Click for frequent words.) 68 NS4B 67 potent inhibitors 67 JAK3 66 druggable targets 66 immunotoxin 65 druggable target 65 undruggable 64 Protein Kinase C 64 immunomodulation 64 VEGF receptor 64 vascular disrupting agents 64 preclinically 64 histone deacetylases 64 engineered RAP peptides 64 Kinases 64 galectin 63 A3 adenosine receptor 63 splice variants 63 ErbB3 63 Tyrima 63 siRNA therapeutic 62 Sphingomab 62 glycosylated 62 NS5A 62 PI3K/mTOR 62 lysophosphatidic acid LPA 62 selective serotonin 2C receptor 62 RNA silencing 62 therapeutic monoclonal antibody 62 recombinant antibodies 62 MEK inhibitors 62 Wnt signaling pathway 62 potent inhibitor 62 noncoding RNA 62 mimetics 62 therapeutic modality 61 TLR8 61 isoform selective 61 HuLuc# 61 immune modulating 61 antiproliferative effects 61 therapeutically relevant 61 chemokine receptor 61 nucleosides 61 cholesteryl ester transfer 61 peptide conjugated 61 molecularly targeted 61 orally bioavailable 61 P#X# 61 glucagon receptor 61 protein tyrosine phosphatase 1B 61 #beta HSD1 61 USP# 61 CCR2 61 eIF 4E 61 selective inhibition 61 siRNA therapeutics 61 JAK2 inhibitor 61 small molecule inhibitors 61 ENMD # 61 SGLT2 inhibitors 61 IGFBP2 61 small molecule activators 61 heparanase 61 Galectins 61 Anticalins 61 antiapoptotic 61 γ secretase 61 HDAC6 61 muscarinic 61 5 HT4 receptor 61 peptide antigens 61 enzymatic reactions 61 HMG CoA reductase 60 NEUGENE 60 Hedgehog pathway 60 thromboxane A2 60 histone methyltransferases HMTs 60 HDACs 60 EphA2 60 cyclophilin D 60 retinoid X 60 IgG1 antibody 60 Membrane proteins 60 ubiquitin ligases 60 posttranslational modifications 60 PKCi 60 potent antiproliferative 60 Hsp# inhibition 60 AT1R 60 glucocorticoid receptor 60 SERMs 60 multiplexed assays 60 Enkephalin 60 cytoprotective 60 Gamma secretase 60 neuronal nicotinic receptors NNRs 60 p# activation 60 HCV protease 60 Upregulation 60 CRTH2 60 TMEM#B 60 PPARγ 60 Nanobody ® 60 Cyclin E 60 FGFR3 60 stapled peptides 60 immunoregulatory 60 proteasome inhibitors 60 VDAs 60 NKX#.# 60 Nanobodies 60 DNA methyltransferases 60 tumor suppressor protein 60 TLE3 60 Curaxins 60 partial agonists 60 Symadex 60 aberrantly activated 60 #ME# 60 cathepsins 60 Nav#.# 60 androgen receptor AR 60 mGluR2 NAM 60 ALK inhibitors 60 affinity antibodies 60 anti angiogenic therapies 60 non coding RNA 60 Notch receptors 60 LSI #P 60 HCV protease inhibitors 60 selectively inhibited 60 selective modulator 60 DHFR 60 p#/CBP 60 PKM2 60 miR #a [002] 60 targeted radiotherapeutic 60 interferon lambda 60 HSP# inhibitor 60 pro angiogenic 60 homodimers 60 PDGFR 60 selective adenosine 60 peptidic 60 rxRNA 60 Fibroblast Growth Factor Receptor 60 Metallophile ™ Technology 60 sd rxRNA 60 CB2 receptor 60 biased ligands 59 conserved sequences 59 potent anticancer 59 therapeutic monoclonal antibodies 59 cytostatic 59 Kinase inhibitors 59 protein tyrosine phosphatase 59 c MET 59 morpholino 59 GKAs 59 mutational analysis 59 micro RNAs 59 selective kinase inhibitors 59 5 HT2A serotonin 59 nucleoside 59 evolutionarily conserved 59 anti angiogenic drugs 59 CXCR4 receptor 59 CCR9 59 JAK STAT 59 experimentally validated 59 site directed mutagenesis 59 Eg5 59 Anticalins R 59 Anticalins ® 59 chemopreventive agent 59 secretory pathway 59 PPARgamma 59 Smac mimetics 59 methyltransferases 59 Interferon beta 59 sphingolipid 59 polyketide 59 CYT# potent vascular disrupting 59 targeting CD# 59 neuroprotective properties 59 chimeric monoclonal antibody 59 epothilone 59 Nedd4 59 epigenetic therapies 59 histone deacetylase HDAC 59 catalytic antibodies 59 transient receptor 59 HSP# inhibitors 59 MEK ERK 59 FGFR 59 histone deacetylase inhibitors 59 DNA gyrase 59 Anticalin ® 59 protein secretion 59 molecular biomarkers 59 selectively inhibit 59 FK# 59 TLR agonists 59 immune stimulatory 59 constitutively expressed 59 Factor Receptor 59 antisense inhibitors 59 prognostic markers 59 physico chemical properties 59 Isis antisense 59 JAK#/JAK# 59 prostanoid 59 MEK1 59 melanocortin receptors 59 biomarker identification 59 CHD5 59 E#F# 59 protein misfolding 59 Angiolix 59 nicotinic receptor 59 RNAi therapeutic targeting 59 oncoprotein 59 humanized antibody 59 sGC 59 FOXO3a 59 multiplex assay 59 hormone gastrin 59 neuroinflammation 59 p# subunit 59 ETBs 59 antiangiogenic agent 59 endogenous ligands 59 tumor hypoxia 59 Cathepsin S 59 Factor VIIa 59 Qdot 59 CDK inhibitor 59 COX enzymes 59 Ets2 59 PI3K inhibitors 58 mGluR5 antagonist 58 U1 Adaptors 58 uricase 58 PARP inhibitors 58 antisense oligonucleotides 58 humanized monoclonal antibodies 58 mTOR signaling pathway 58 ERK signaling 58 treating neuropathic pain 58 kinase inhibition 58 TriRima 58 chemopreventive agents 58 JAK2 enzyme 58 gamma secretase inhibitors 58 gamma secretase activating 58 FSH receptor 58 single stranded oligonucleotides 58 TLR9 agonists 58 NKG2D 58 CCR9 antagonist 58 isoprenoid 58 mutated K ras 58 plectasin 58 GMX# 58 p# mutations 58 potent cytotoxic 58 A2A receptor 58 p# MAPK 58 ErbB3 HER3 58 pharmacologic intervention 58 MAPK pathway 58 5 hydroxymethylcytosine 58 mediated inhibition 58 specific lectin receptors 58 orally administered inhibitor 58 insulin sensitizers 58 LDL receptor 58 demethylase 58 cleavable linker 58 ddRNAi 58 JAK inhibitors 58 proteasome inhibitor 58 granzyme B 58 pharmacologically relevant 58 enzyme inhibitor 58 inhibiting tumor 58 metabolic enzymes 58 peroxisomal 58 mRNA sequences 58 selective agonists 58 therapeutically beneficial 58 CRAC channel 58 PET tracers 58 tubulin inhibitors 58 stable nucleic acid 58 Cytolin R 58 LRRK2 58 Pertuzumab 58 pleiotropic 58 endothelin receptors 58 oxysterols 58 58 glutathione peroxidase 58 anti CD3 58 PPARg 58 acadesine 58 apoptotic pathway 58 undruggable targets 58 sequence homology 58 TG2 58 GSK3B 58 amyloid peptide 58 protein tyrosine phosphatases 58 procaspase 3 58 AMPK activators 58 immune modulator 58 multipotent 58 transgene expression 58 MALAT1 58 TGF β 58 validating biomarkers 58 Receptors GPCRs 58 inhibit angiogenesis 58 ALV# 58 GRP# 58 ligases 58 HDAC inhibitors 58 colony stimulating factor 58 NTDDS 58 developing TB4 58 IMPDH 58 multitargeted 58 chemoresistant 58 histone deacetylase HDAC inhibitors 58 PKC isoforms 58 triphosphate 58 glutamate receptors 58 GPx 58 p# inhibitor 58 sarcosine 58 thrombin receptor 58 deacetylase inhibitors 58 miRagen 58 neuroregenerative 58 RAR beta 58 biologic therapeutics 58 vinca alkaloid 58 Transfection Reagent 58 histone acetyltransferase 58 axonal degeneration 58 Squalamine 58 activating mutation 58 Monoclonal antibodies 58 PI3K Akt 58 tumor antigen 58 CCX# 58 allosteric 58 polyamine 58 immunomodulatory 58 thymidylate synthase 58 DLC1 58 ARF1 58 FGFR2 58 pDCs 58 Nanobodies ® 58 GABAB receptors 58 nucleoside analogues 58 JAK1 58 PTP 1B 58 cell adhesion molecules 58 UsiRNAs 58 inhibit replication 58 synthetic siRNA 58 gene inactivation 58 terminally differentiated 58 resolvins 58 FGFR4 58 HCV replication 58 predictive biomarkers 58 substrate specificity 58 gamma secretase 57 multigenic 57 metabonomics 57 GPCR targets 57 CTLs 57 FUS1 57 Xanafide 57 acetylcholinesterase AChE 57 intracellular signal transduction 57 radioprotective 57 paxillin 57 antitumoral 57 M2 subunit 57 RONDEL 57 dimerization 57 tyrosine phosphorylation 57 IDO inhibitor 57 Src inhibitors 57 Notch1 57 LSD1 57 TGR5 57 RAS RAF MEK 57 C5aR 57 Lisofylline 57 peroxidase 57 FGFs 57 proto oncogene 57 misfolded SOD1 57 EGFR pathway 57 Stat5 57 HIF 1a 57 phosphodiesterase inhibitors 57 PDE# 57 enzyme inhibitors 57 Nanobody 57 Hh pathway 57 PI3K delta 57 Lyn kinase 57 pyruvate kinase 57 bacterial enzyme 57 metaglidasen 57 anticancer agent 57 pharmacological chaperone 57 MTP inhibitor 57 incretin 57 diagnostic biomarkers 57 Onconase 57 Hedgehog inhibitor 57 eotaxin 57 methylated DNA 57 PROfusion 57 TGF beta1 57 norepinephrine reuptake inhibition 57 selectively binds 57 beta subunit 57 reverse transcriptase inhibitors 57 histone deacetylase inhibitor 57 virulence genes 57 Pancreate ™ 57 Cdc7 57 mda 7 57 polyamines 57 taxane derivative 57 Fc receptor 57 galanin 57 potentiator 57 SIRT1 activators 57 mGluR5 antagonists 57 adenosine receptor 57 signal transduction inhibitors 57 Exelixis XL# 57 lipid particles 57 hematopoietic cells 57 vWF 57 DsiRNA 57 Guanilib 57 mevalonate 57 non nucleoside 57 Mcl 1 57 antitumour 57 MUC1 * 57 anticancer therapeutics 57 PTPN# 57 mitochondrial toxicity 57 alternatively spliced 57 anticancer therapies 57 HDAC inhibition 57 FoxO1 57 ANTISENILIN ® 57 PI3K inhibitor 57 antifibrotic 57 KIT mutations 57 NNRs 57 novel anticancer 57 bispecific 57 tranilast 57 triphendiol 57 cyclin dependent kinase inhibitor 57 pathophysiological effects 57 siRNA mediated 57 HIF PH 57 Fc fusion protein 57 Angiocept 57 targeting PCSK9 57 anti fibrotic 57 pharmacologically 57 EndoTAG TM -1 57 potent inhibition 57 PHD2 57 IGF1R 57 nanocarriers 57 PDGF receptor 57 chemically modified siRNA 57 dimeric 57 PI3K/AKT 57 pertussis toxin 57 Allosteric 57 genetic loci 57 proteases 57 neurotrophic 57 clonogenic 57 IgG1 57 novel immunomodulatory 57 isotype 57 biomarker assays 57 mGluR 57 renin inhibitors 57 TAT# 57 phosphorylated proteins 57 fatty acid synthase 57 peptide receptor 57 Spiegelmers 57 delipidation 57 coexpression 57 CDKs 57 Epothilones 57 NADPH oxidase 57 intracellular signaling pathways 57 LNP formulations 57 protein tyrosine kinase 57 SGLT inhibitors 57 neuro protective 57 PKC# 57 receptor tyrosine kinase inhibitor 57 oncolytic 57 ghrelin antagonist 57 annexin V 57 GAP #B# 57 Protein Kinase 57 IFNs 57 Curaxin 57 immunomodulatory properties 57 SIRT3 57 G Protein Coupled 57 aptamers 57 neoplastic transformation 57 ribonuclease 57 alpha fetoprotein AFP 57 AMPAKINE 57 beta lactams 57 activin 57 cardioprotective effects 57 MDR1 57 Anticalin 57 p#NTR 57 AFFiRiS 57 DNA demethylation 57 DCCR 57 HCV polymerase 57 geldanamycin 57 intracellular pathogens 57 trans splicing 57 molecular abnormalities 57 CYP #D# 57 antiproliferative activity 57 Anticalin R 57 Smac mimetic 57 secreted protein 56 miR #b [002] 56 CB1 antagonists 56 therapeutically useful 56 clinically validated targets 56 peptide therapeutics 56 selective inhibitors 56 asymmetric catalysis 56 SERCA2a 56 LED# 56 immunomodulating 56 investigational therapies 56 adipogenic 56 Tumour Vascular Disrupting Agent 56 cyclooxygenase 56 Talabostat 56 thymidylate synthase TS 56 PDE7B 56 short hairpin RNAs 56 S6K 56 Aviptadil 56 Sanger Sequencing 56 antiangiogenic 56 EphB4 56 trimeric 56 Gleevec resistant 56 hpSCs 56 siRNAs targeting 56 antibody cytokine 56 Hsp# [001] 56 NKT cells 56 syntaxin 56 binds selectively 56 ubiquinol 56 Dysregulation 56 viral polymerase 56 albumin binding 56 synthetic peptides 56 EGF receptor 56 cyclase 56 tubulin inhibitor 56 CD#b 56 insulin sensitizing 56 soluble proteins 56 receptor subtypes 56 iPSC 56 favorable pharmacokinetic profile 56 recombinant fusion 56 beta secretase inhibitors 56 transmembrane proteins 56 human pluripotent stem 56 eprotirome 56 renal fibrosis 56 silico prediction 56 antitumor 56 Stapled Peptide 56 antiangiogenesis 56 eicosanoid 56 Fleximer 56 peptide mimetics 56 dopamine receptor 56 neuroligins 56 dihydrofolate reductase 56 monoclonals 56 PROCHYMAL 56 Vidofludimus 56 HERV 56 TAp# 56 biosynthetic 56 microRNA biomarkers 56 ASONEP 56 inhibit metastasis 56 LHRH antagonists 56 cytidine 56 MetAP2 56 thyroid hormone receptor 56 AVI NEUGENE 56 DNA intercalator 56 NOD mouse 56 NS4A 56 glycolipids 56 epigenetically 56 Phage Pharmaceuticals 56 prodrugs 56 Caspases 56 small molecule defensin 56 trans isomers 56 novel peptide 56 TNFa 56 Trofex 56 glycosyltransferase 56 pharmacologically active 56 Alpha lipoic acid 56 apoptosis inducing 56 proliferative disorders 56 Elvitegravir 56 BiTE 56 secreted proteins 56 orally bioavailable mimics 56 liposomal formulation 56 pleiotropic effects 56 renin inhibition 56 vidofludimus 56 binding affinities 56 Dystrophin 56 sCD# 56 HyACT 56 Chemokine Receptor 56 C#T [002] 56 Panzem R NCD 56 hepatotoxic 56 lentiviral vectors 56 agonism 56 XmAb# 56 novel anticancer therapies 56 Anti angiogenic 56 pharmacokinetic interactions 56 cathepsin B 56 LKB1 56 NF kB pathway 56 shRNA libraries 56 Hsp# inhibitors 56 MTP inhibitors 56 lysosomal storage diseases 56 p# alpha [002] 56 Biomerk Tumorgrafts 56 S#P# 56 synthetic ligand 56 selective agonist 56 TrkB 56 TGF ß 56 3p siRNAs 56 IAP inhibitor 56 N glycan 56 adenoviral 56 polymerase inhibitors 56 Aliskiren 56 Bendavia 56 nanomolar range 56 HepDirect 56 tryptase 56 stimulate insulin secretion 56 Valproic acid 56 NF kappaB activation 56 NR2B subunit 56 enzymatically active 56 heterodimers 56 drug conjugates 56 vivo validation 56 nicotinic alpha 7 56 TRPV4 56 WT1 56 labetuzumab 56 Virulizin ® 56 neuroprotectant 56 KLF4 56 synaptogenesis 56 nanobacteria 56 PTEN gene 56 erythropoietic 56 optimized siRNA 56 nicotinic acetylcholine receptor 56 beta1 integrin 56 phosphatases 56 ligand TRAIL 56 c MYC 56 Bortezomib 56 PDE4 inhibitors 56 Cardiotoxicity 56 chemopreventive 56 MDSCs 56 TLR9 agonist 56 PDE4 inhibitor 56 Alfacell proprietary ribonuclease 56 Panzem R 56 endoxifen 56 PDGF alpha receptor 56 cyclic AMP cAMP 56 Carfilzomib 56 MMP9 56 THR beta agonist 56 Immunotherapeutic 56 MALDI-TOF/TOF 56 ZFP TFs 56 Trophos 56 synthetic analogues 56 integrin receptors 56 mAbs 56 ERK pathway 56 romazarit 56 sodium glucose transporter 56 Aromatase 56 fatty acid biosynthesis 56 Anavex #-# 56 histone deacetylase 56 anticancer agents 56 FTIs 56 GPCRs 56 MAbs 56 telomere dysfunction 56 Th# 56 oral prodrug 56 NFκB 56 Src kinase 56 transduce 56 theranostic 55 IKK2 55 NFkB 55 Mipomersen 55 mtDNA mutations 55 Pancreate 55 tumorigenic 55 calcitonin gene related 55 c Myb 55 antimitotic 55 S#A# [002] 55 cholesterol biosynthesis 55 glycosylation profile 55 kinase inhibitors 55 alpha7 55 RhuDex ® 55 OMP #M# 55 nonviral 55 quinone 55 Interferon alpha 55 glucocorticoid receptors 55 monodisperse 55 murine models 55 Th2 cytokines 55 oligomers 55 rhIL 7 55 replicative senescence 55 ERK1 2 55 ERK5 55 costimulation 55 MEK inhibitor 55 TG# [003] 55 5 HT6 55 antisense drugs 55 short interfering RNA 55 Prodarsan ® 55 ActA 55 bifunctional 55 immunostimulatory effects 55 highly selective endothelin 55 TGF b 55 racemic mixture 55 synthetic lethality 55 biologic pathways 55 PDE4 55 RNA antagonists 55 breast cancer subtypes 55 Elevated serum 55 inhibit viral replication 55 IL 1ß 55 protein kinase inhibitor 55 IAP inhibitors 55 eIF4E 55 CFTR inhibitors 55 Mutational 55 oncoproteins 55 biocatalytic 55 amyloid beta peptides 55 cytokine signaling 55 TNF receptors 55 prostaglandin D2 55 mTOR inhibitors 55 CDK inhibitors 55 pRb 55 FKBP# 55 Litx 55 Preclinical studies suggest 55 GFT# 55 anti angiogenic agent 55 oligomerization 55 allosteric modulator 55 peptidomimetic 55 reverse transcriptase 55 hepatic lipase 55 antibody mediated 55 transmembrane protein 55 histone deacetylases HDACs 55 chaperone proteins 55 antisense compounds 55 NO synthase 55 receptor partial agonist 55 chemically modify 55 K ras mutations 55 Corgentin 55 TRAF6 55 inhibiting viral replication 55 immune modulatory 55 AEG# 55 serotonin receptor 55 phosphatidylserine PS targeting 55 neuroinflammatory 55 investigational humanized monoclonal antibody 55 amyloidogenic 55 Olaparib 55 DFMO 55 potentiating 55 ENaC 55 Pepducin 55 urokinase plasminogen activator 55 CEQ# 55 Pathway Inhibitor 55 LTB4 55 miRs 55 Bruton tyrosine kinase Btk 55 cyclooxygenase COX 55 oxidative stress inducer 55 Retinoic Acid 55 lymphotoxin 55 POTELLIGENT ® 55 #HT#A 55 telomerase inhibitor 55 glycolytic 55 Stromal 55 glutamyl 55 anti secretory 55 alkylating 55 bcl 2 55 small molecule tyrosine 55 Fas ligand 55 tezampanel 55 biosynthetic pathways 55 ADME properties 55 TKM ApoB 55 abzymes 55 ubiquinone 55 NPC#L# 55 Adnectin 55 Ii protein 55 antisense inhibition 55 HQK 55 FAAH 55 transfection reagents 55 muscle contractility 55 RIP1 kinase 55 Elesclomol 55 epothilones 55 HCV NS3 protease 55 JUVISTA R Human 55 polymerase inhibitor 55 ADDLs 55 unnatural amino acids 55 Microtubule 55 sodium glucose cotransporter 55 RayBiotech 55 Methotrexate MTX 55 M1 muscarinic 55 CTAP# Capsules 55 apoptosis pathway 55 RNAi compounds 55 TRAIL induced apoptosis 55 hypermethylation 55 lipoprotein metabolism 55 signal transduction 55 Umbilical cord stem cells 55 B7 H4 55 cyclin E 55 5 HT2A inverse 55 immunostimulatory 55 aT cell 55 thermostable 55 thioredoxin 55 HIF 1α 55 systemically administered 55 kidney urologic 55 pharmacologic agents 55 Micro RNAs 55 preferentially bind 55 #T# L1 55 Viprovex TM 55 Vincent Mutel CEO 55 flavopiridol 55 act synergistically 55 FGF2 55 HbF 55 Klf4 55 VEGF receptors 55 dihydrofolate reductase DHFR 55 cytolytic 55 PI3K AKT 55 synthetic retinoid 55 receptor blocker 55 MT1 MMP 55 TGFβ 55 Sudhir Agrawal D.Phil 55 Endotis 55 IRF5 55 dehydrogenases 55 immune modulators 55 NFAT 55 INT# [002] 55 SPC# [001] 55 antisense drug 55 intracellular pathways 55 PTP1B 55 covalently bound 55 intracellular protein 55 NovaBay Aganocide compounds 55 insertional mutagenesis 55 CYP#B# 55 Clusterin 55 Proteases 55 bioactive lipids 55 Inhaled corticosteroids 55 autism susceptibility genes 55 BRAF inhibitors 55 pyrimidines 55 CGEN # 55 receptor agonists 55 inverse agonist 55 constitutively activated 55 clinically differentiated 55 siRNA duplexes 55 iRGD 55 intracellular bacteria 55 Ampligen r 55 siRNA sequences 55 lysosomal 55 Novosom 55 VeraTag 55 opioid antagonists 55 Amplimexon 55 selective receptor agonist 55 colorectal carcinogenesis 55 plasma lipid 55 Viamet 55 plasminogen 55 induce pluripotency 55 AMACR 55 neuroprotection 55 PDE#A 55 miR #a [001] 55 theranostics 55 N acetyltransferase 55 Enzastaurin 55 secretase 55 replicon

Back to home page