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(Click for frequent words.) 74 mice genetically engineered 73 transgenic mice 73 knockout mice 71 genetically modified mice 70 genetically altered mice 70 mutant mice 69 mice lacking 67 mice 65 telomerase gene 64 mouse embryos 64 mutant mouse 64 mutant protein 63 genetically engineered mouse 63 deficient mice 63 neural cells 63 mutant flies 63 ES cells 63 mutant proteins 62 transgenic mouse model 62 Pin1 62 mice genetically altered 62 p# gene 61 GFP gene 61 mammary cells 61 iPSCs 61 c Myc 61 Foxp3 61 prion proteins 61 genes encoding 61 breast epithelial cells 61 PKM2 60 apoE 60 PrP 60 zebrafish 60 transgenic mouse 60 neural stem cells 60 pancreatic cells 60 transgenic rats 60 iPS cells 60 Wnt#b 60 Skp2 60 gene 60 nematode worms 60 C EBP alpha 60 HOTAIR 60 mammalian cells 59 chimeric mice 59 stathmin 59 leptin receptors 59 zebrafish embryos 59 leptin 59 proteins 59 CaMKII 59 miR #a [002] 59 Notch signaling 59 TNFa 59 SH2 B 59 ubiquitylation 59 C. elegans 59 UCP2 59 tumor suppressor gene 59 Wnt signaling 58 genetically altered mouse 58 yeast cells 58 tumor suppressor protein 58 GABAergic neurons 58 Hsp# [001] 58 leptin receptor 58 genes 58 cultured cells 58 nestin 58 mutant worms 58 Pten 58 fibroblast cells 58 melanopsin 58 estrogen receptor alpha 58 Akt1 58 GBM tumors 58 androgen receptor 58 reprogramming genes 58 protein encoded 58 SIRT1 gene 58 NKT cells 58 TAp# 58 induced pluripotent cells 58 cardiomyocytes 58 RGS2 58 SIRT1 58 neuroblastoma cells 58 follistatin 58 microRNAs 58 RUNX3 58 mutant SOD1 58 progerin 58 cyclin D1 58 laforin 58 reprogrammed cells 58 CXCL# 58 FGF# 58 chitinase 58 hair follicle stem cells 57 cultured neurons 57 MAPCs 57 S#A# [002] 57 myostatin gene 57 XBP1 57 Kv#.# 57 miRNAs 57 tumor suppressor genes 57 GRK2 57 HSCs 57 oncogenes 57 Wnt1 57 lung fibroblasts 57 PPARγ 57 overexpress 57 SIR2 gene 57 molecular mechanism 57 SIRT3 57 mutant strains 57 hypocretin 57 myostatin 57 FMR1 gene 57 TRPA1 gene 57 mouse embryo 57 MDM2 57 gene encoding 57 humanized mice 57 Myc 57 germ cells 57 RNA molecule 57 C1q 57 E cadherin 57 lentiviruses 57 LIS1 57 SMN protein 57 PTEN gene 57 CatB 57 pRb 57 humanized mouse 57 GDNF 57 caveolin 1 57 PTEN protein 57 imprinted genes 57 vimentin 57 histone modifications 57 insulin receptors 57 mutant gene 56 catenin 56 CD8 T cells 56 FUS1 56 microglial cells 56 normal prion protein 56 glioblastoma cells 56 micro RNAs 56 BACE1 56 skin fibroblasts 56 WT1 56 fission yeast 56 OCT4 56 p#NTR 56 epigenetically 56 zebrafish embryo 56 DGAT1 56 cyclophilin D 56 demethylase 56 nNOS 56 cyclins 56 Wwox 56 oncoprotein 56 miR #b [001] 56 BMP signaling 56 fluorescent protein 56 gene expression 56 Wnt 56 PGE2 56 p# protein 56 TGF beta 56 activin 56 retinoic acid 56 MeCP2 56 endostatin 56 alpha synuclein gene 56 molecular pathways 56 Schwann cells 56 protein fragment 56 AMPK 56 dendritic cells 56 immune cells 56 primordial germ cells 56 micro RNA 56 aP2 56 IKK2 56 granule cells 56 transplanted stem cells 56 mRNA transcripts 56 glioma cells 56 diabetic mice 56 fibroblasts 56 causative genes 56 TGF β 56 Math1 56 neurofibromin 56 interfering RNA 56 hormone receptors 56 enzyme 56 hippocampal neurons 56 oncomodulin 56 molecular pathway 56 Klotho gene 56 IGFBP2 56 IGF2 56 podocytes 56 neurons 56 telomerase 56 BALB c 56 beta catenin 56 luciferase 56 gene expression patterns 56 thymosin 56 miR #a [001] 56 progranulin 56 db db mice 56 myoblasts 56 DISC1 56 Tregs 56 HHMI investigator 56 transgene 56 GRP# 56 LKB1 56 apoptotic pathway 56 signaling pathway 56 furin 55 myocytes 55 DLC1 55 kalirin 55 connexin 55 PINK1 55 calpain 55 methylation patterns 55 NFkB 55 cryopyrin 55 receptors 55 chimeric gene 55 triptolide 55 phenotype 55 BDNF gene 55 Htt 55 Nkx#.# 55 mutated gene 55 CEACAM1 55 DLX5 55 SAPAP3 55 TRAF6 55 BCL#A 55 genotoxic stress 55 calcineurin 55 virulence genes 55 Hox genes 55 metabolic enzymes 55 NF kB 55 SOD1 protein 55 mitochondrial dysfunction 55 iPSC 55 PTPN# 55 NK cells 55 glial cell 55 Mice genetically engineered 55 planarians 55 mRNAs 55 hormone leptin 55 Neuregulin 1 55 arginase 55 Cx# [001] 55 PTP1B 55 SATB1 55 antisense RNA 55 GPR# [002] 55 piRNAs 55 dystroglycan 55 tetramers 55 p#INK#a 55 cystic fibrosis transmembrane conductance 55 neuroligin 55 murine 55 STAT4 55 epigenetic silencing 55 Mice lacking 55 TERT 55 c myc 55 Myostatin 55 hypermethylation 55 copper zinc superoxide 55 skeletal muscle cells 55 transgenic mouse models 55 motor neuron 55 retinoblastoma protein 55 Jhdm2a 55 Nrf2 55 bacterium Escherichia coli 55 retinal degeneration 55 ChR2 55 FGF2 55 microglial 55 DEAR1 55 KLF# 55 overexpression 55 Wnt signaling pathway 55 mitochondria 55 transcription factors 55 glia 55 Akt 55 BMP4 55 mutant huntingtin 55 planaria 55 SOD1 gene 55 receptor protein 55 proto oncogene 55 protein 55 enzymatic activity 55 CCR7 55 p#Kip# 55 prion protein 55 neuronal cells 55 kisspeptin 55 Mcl 1 55 stress hormone corticosterone 55 gene p# 55 inosine 55 interferon gamma 55 paxillin 55 neurones 55 fatty acid synthase 55 antibodies 55 LRRK2 55 ERa 54 astrocytes 54 ADDLs 54 genetic alteration 54 Peutz Jeghers syndrome 54 adhesion molecule 54 eotaxin 54 ghrelin 54 HER2 neu 54 GLI1 54 RANKL 54 fruitflies 54 bone marrow stem cells 54 RNA molecules 54 BH4 54 Brd4 54 endothelial cells 54 HSP# 54 lincRNAs 54 TGF ß 54 Sirt3 54 mitochondrial proteins 54 Sir2 54 IRF5 54 DNMT1 54 abnormal prions 54 glycoproteins 54 neural progenitor cells 54 glutamate receptors 54 inbred strains 54 missense mutation 54 IL 1beta 54 Th# cells 54 leptin deficient 54 C. elegans mutants 54 neurogenesis 54 BRCA1 gene 54 ceramide 54 CD# protein 54 NFATc1 54 PAR1 54 siRNAs 54 noncoding RNAs 54 FOXP3 54 Sox2 54 TLR2 54 S#K# 54 var genes 54 tau protein 54 SGK1 54 progenitor cells 54 oxysterols 54 mutated genes 54 cardiac fibroblasts 54 transcriptional repression 54 neutralizing antibody 54 SIR2 54 constitutively 54 Cdk5 54 fatty acid metabolism 54 beta1 integrin 54 toxic beta amyloid 54 transposon 54 AgRP neurons 54 NRG1 54 beta galactosidase 54 stathmin gene 54 uncoupling protein 54 dynamin 54 microglia 54 autoimmune encephalitis 54 STAT3 54 SOD1 54 Six3 54 siRNA knockdown 54 vascular endothelial cells 54 Helicobacter 54 neuroligins 54 CHD7 54 PP2A 54 mouse embryonic stem 54 dystrophin 54 synapse formation 54 selective inhibitors 54 hepatocytes 54 islet cells 54 DUX4 54 mutant genes 54 Klf4 54 MC4R gene 54 hTERT 54 PGC 1alpha 54 Przedborski 54 miR# 54 cardiac myocytes 54 TrkB 54 RNA transcripts 54 Rad# 54 insulin secreting cells 54 normal prion proteins 54 TRPV1 54 osteoblasts 54 luteolin 54 normal littermates 54 signaling molecule 54 Nrf2 gene 54 POMC neurons 54 BMAL1 54 coreceptor 54 keratins 54 isoforms 54 telomerase enzyme 54 microRNA miR 54 Id1 54 histone 54 Caenorhabditis elegans 54 Smad3 54 Neu5Gc 54 NMDA receptors 54 germline stem cells 54 SIRT6 54 palladin 54 Wnts 54 CIB1 54 glucocorticoid receptors 54 receptor molecule 54 estrogen receptor 54 Treg cells 54 VHL gene 54 embryonic stem ES 54 Dpp 54 Akt3 54 hippocampal cells 54 genomic instability 54 intestinal epithelial cells 54 Wnt pathway 54 MeCP2 protein 54 alpha synuclein 54 lipin 54 IGFBP7 54 Oct4 54 viral vector 54 tumor cells 54 Mdm2 54 myogenesis 54 LMNA 54 luminal cells 54 small interfering RNA 54 sphingolipid 54 microRNAs miRNAs 54 EphA2 54 flavopiridol 54 fluorescent molecules 54 mutated protein 53 PPAR gamma 53 hematopoietic cells 53 bryostatin 53 orexin 53 proteases 53 mutant p# 53 uPAR 53 retinal cells 53 Cre recombinase 53 PPAR delta 53 clusterin 53 telomerase reverse transcriptase 53 EGFRvIII 53 β catenin 53 ion channels 53 longdaysin 53 B7 H1 53 genetic manipulations 53 EZH2 53 TMEM#B 53 FANCD2 53 iPS cell 53 SOCS1 53 astrocyte 53 Neural stem cells 53 aldose reductase 53 Jagged1 53 neural crest cells 53 LRRK2 gene 53 tumor suppressing 53 immunized mice 53 fibrocytes 53 CCR5 receptors 53 antigen receptor 53 TACI 53 AMPA receptors 53 Srs2 53 RKIP 53 myotonic dystrophy 53 HMGA2 53 OGG1 53 roundworms 53 transplanted bone marrow 53 skeletal muscle actin 53 NF kappaB 53 phosphorylated 53 microRNA molecules 53 PC# cells 53 receptor 53 Sonic hedgehog 53 HDAC2 53 galanin 53 genetic mutations 53 MyoD 53 FOXO1 53 STAT1 53 retroviruses 53 miR 53 MEF2C 53 OPHN1 53 inhibitory receptors 53 iNOS 53 SH#B# 53 TRIM5 53 NPY AgRP neurons 53 mutations 53 mutant zebrafish 53 lentivirus 53 utrophin 53 neurite outgrowth 53 RNA splicing 53 myeloid cells 53 p# pathway 53 c MYC 53 TRPV4 53 skeletal muscle 53 NKX#.# 53 FKBP# 53 cPLA2 53 serotonin receptor 53 selective inhibition 53 losartan 53 Smurf1 53 palmitoylation 53 molecular mechanisms 53 tau proteins 53 stem cells 53 nerve cells 53 mutant alleles 53 cybrids 53 ERK1 2 53 primary cilia 53 hedgehog signaling pathway 53 transthyretin 53 yeast prions 53 dystrophin gene 53 acetylation 53 nicotinic receptors 53 ncRNAs 53 fibrillin 1 53 urocortin 53 Notch receptor 53 doublecortin 53 p# deficient 53 GPR# [001] 53 undergo apoptosis 53 Clusterin 53 phytochrome 53 pyruvate kinase 53 hedgehog pathway 53 retrovirus 53 cell signaling pathways 53 Transgenic mice 53 anthrax toxin 53 HER2 receptors 53 amyloid ß 53 calorically restricted 53 MECP2 53 FDDNP 53 myosin VI 53 interferon pathway 53 amyloid protein 53 neural crest stem cells 53 peptides 53 Or#b 53 amyloids 53 CDK4 53 ERK2 53 RNAs 53 leptin hormone 53 methylation 53 Vpu 53 membrane protein 53 overexpressing 53 CFTR 53 Sox9 53 JAK STAT 53 neuronal stem cells 53 E1A 53 mesenchymal 53 plexin D1 53 pDCs 53 outer membrane proteins 53 caveolae 53 defensins 53 RNA sequences 53 biosynthetic pathway 53 Runx2 53 LRP1 53 upregulated 53 suppressor gene 53 Arabidopsis plants 53 calcium homeostasis 53 HIF 1α 53 rhodopsin 53 lentiviral vectors 53 cells 53 hypermethylated 53 opsins 53 phosphorylates 53 inhibitory receptor 53 neuronal pathways 53 LDL receptor 53 PKC beta 53 miRNA genes 53 channelrhodopsin 53 Siglec 8 53 plasminogen 53 granulocytes 53 nAChR 52 Stat3 52 mitochondrial 52 nicotinamide 52 trophoblast cells 52 lacZ 52 SMN1 52 phage 52 mesenchymal cells 52 HDAC inhibitors 52 LDLR 52 dsRNA 52 KSHV 52 HDAC 52 genetic alterations 52 protein kinase C 52 motor neurons 52 NKCC1 52 fluorescent probes 52 receptor proteins 52 TEL AML1 52 TGF alpha 52 constitutively active 52 centrosomes 52 huntingtin protein 52 epigenetic marks 52 Genetically engineered mice 52 glycolysis 52 MAPK 52 N Myc 52 glycosylation 52 PECAM 1 52 protein synthesis 52 cypin 52 EGF receptor 52 globin genes 52 pericytes 52 Alu elements 52 proteins encoded 52 cannabinoid receptors 52 chromosomal aberrations 52 kinase gene 52 SCD1 52 TSLP 52 microcephalin 52 ESCs 52 antisense inhibition 52 telomere dysfunction 52 germline cells 52 p# mutations 52 medulloblastomas 52 SIRT1 protein 52 epigenetic changes 52 CCL# 52 gamma secretase inhibitor 52 protein dystrophin 52 Prox1 52 MIF gene 52 measles virus 52 mammalian 52 gene mutation 52 derived neurotrophic factor 52 hypothalamic neurons 52 prion protein gene 52 Klotho 52 hedgehog signaling 52 hyperactivation 52 zebra fish 52 osteocalcin 52 Hox gene 52 LRAT 52 MHC molecules 52 orexin receptors 52 dopamine neurons 52 HSF1 52 KLF4 52 tRNAs 52 5 hydroxymethylcytosine 52 NF1 gene 52 Nanog 52 messenger RNAs mRNAs 52 PKD1 52 FGF signaling 52 melanoma tumors 52 Fibroblasts 52 bcl 2 52 poxvirus 52 mtDNA mutations 52 biological molecules 52 hairless mice 52 fascin 52 tumor suppressor 52 enzymes 52 regulated kinase ERK 52 breast cancer metastasis 52 transcriptional activation 52 p# [001] 52 adaptive immunity 52 HER2/neu 52 Atoh1 52 human ESCs 52 PDE#A 52 lysin 52 adenovirus 52 sirtuin 52 RGS# 52 oligodendrocytes 52 polymerases 52 Myb 52 chromatin structure 52 NPY 52 IL 7R 52 cholesterol metabolism 52 Salk researchers 52 inhibitory neurons 52 chromosomal DNA 52 mitochondrial respiration 52 TLR3 52 Cyclin D1 52 BRAF mutation 52 gene variant 52 RhoA 52 porphyrins 52 PB1 F2 52 neural stem cell 52 short hairpin RNA 52 shRNAs 52 downregulated 52 beta subunit 52 viral vectors 52 morphogen 52 Stat5 52 transfected 52 FAK 52 ALDH 52 Pax3 52 FGFR1 52 IL 1β 52 osteopontin 52 IRAK1 52 HCV replication 52 rhesus monkeys 52 T lymphocytes 52 artificial chromosomes 52 radial glia 52 thioredoxin 52 odorant receptor 52 hepcidin 52 stromal cells 52 Th2 52 GSTP1 52 beta spectrin 52 NADPH oxidase 52 CFTR gene 52 Smoothened 52 BMP2 52 suppressor cells 52 Drosophila 52 epigenetic alterations 52 cofilin 52 Pten gene 52 naturally occurring enzyme 52 effector functions 52 FOXP2 52 spontaneous mutations 52 Rap1 52 oxidative phosphorylation 52 HBx 52 Th2 cytokines 52 noncoding RNA 52 PPAR alpha 52 LXRs 52 IKK beta 52 NKT cell 52 neuropilin 52 misfolded 52 Syk 52 IKKa 52 bioengineered mice 52 Hypoxia Inducible Factor 52 endocannabinoids 52 FOXP3 gene 52 tau gene 52 c Abl 52 polyamines 52 ACh 52 neurotrophin 52 BCL6 gene 52 ribozyme 52 ubiquitination 52 basal cells 52 Arf gene 52 messenger RNAs 52 bacterial enzymes 52 Ph.D. postdoctoral fellow 52 non coding RNA 52 Lrp5 52 TGF ß1 52 HER2 protein 52 CD#L 52 SMN2 52 HepG2 cells 52 hepatocyte 52 IRE1 52 Notch1 52 Src 52 habenula 52 sortilin 52 adult neurogenesis 52 fruitfly Drosophila 52 nonhuman primate 52 Velculescu 52 NF kB pathway 52 Hfq 52 tyrosine kinases 52 lamin 52 gene sequences 52 SWI SNF 52 matrix metalloproteinases 52 CXCL5 51 tumor suppressors 51 Frizzled 51 PEDF 51 epigenetic mechanisms 51 neuregulin 1 51 genetic variants 51 MAP kinase 51 Epstein Barr virus EBV 51 synaptic function 51 vomeronasal organ 51 PRDM# 51 cardiomyocyte 51 olfactory neurons 51 molecule 51 gene variants 51 skeletal muscles 51 embryonic stemcells 51 fusion protein 51 Nf1 51 CB2 receptor 51 obestatin 51 naturally occurring molecule 51 phosphorylate 51 mRNA 51 IGF1 51 sooty mangabeys 51 hESCs 51 huntingtin 51 E#F# 51 autophagy 51 Pdx1 51 transgenic zebrafish 51 ErbB4 51 JAK2 enzyme 51 MC4R 51 tumor antigen 51 HDAC6 51 shRNA 51 Her2/neu 51 CFTR protein 51 innate immune response 51 MT1 MMP 51 macrophages 51 Xenopus 51 E3 ubiquitin ligase 51 PKCi 51 antisense molecules 51 microRNA 51 cells overexpressing 51 autoantibodies 51 familial ALS 51 endoxifen 51 biochemical pathways 51 genetic mutation 51 Fc receptor 51 cellular signaling pathways 51 MAPKs 51 circadian cycles 51 NKX2 51 NMDA receptor 51 T cadherin 51 Huntingtin 51 neuropeptides 51 enzymatic pathway 51 senescent cells 51 Hh 51 coexpression 51 oxidized lipids 51 oxyntomodulin 51 dentate gyrus 51 telomere shortening 51 IL #R 51 GSTM1 51 worm C. elegans 51 adiponectin 51 undifferentiated hESCs 51 gene encodes 51 mouse oocytes 51 Rhes 51 mouse ESCs 51 plectasin 51 ubiquitin ligase 51 FMRP 51 tiny roundworm 51 telomerase activity 51 blastomeres 51 NFKBIA 51 neuropeptide Y NPY 51 roundworm C. elegans 51 melanocyte stimulating hormone 51 heterodimers 51 neurobiologists 51 secretory cells 51 transgenic animals 51 amyloid deposition 51 CPEB 51 enkephalin 51 P. gingivalis 51 trophoblasts 51 p# INK4a 51 MDSCs 51 ERBB2 51 chromatid 51 HuR 51 biochemical pathway 51 hepatoma 51 androgen receptors 51 GAPDH 51 DISC1 gene 51 inactive X chromosome 51 FOXP2 gene 51 NR2B 51 histone deacetylase inhibitors 51 ependymal cells 51 CHO cells 51 arrestin 51 hematopoietic stem cells 51 costimulatory 51 prions 51 cisplatin resistant 51 small molecule inhibitors