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(Click for frequent words.) 74 ERK1 2 74 M1 muscarinic 74 HepG2 cells 72 methyltransferase 72 cell adhesion molecule 71 metalloproteinase 71 4E BP1 71 RAS RAF MEK 71 IFN γ 71 GSTP1 71 pDC 71 ERK pathway 71 antiapoptotic 70 cyclic AMP cAMP 70 VEGFR1 70 neurite outgrowth 70 serine threonine 70 acyl CoA 70 intercellular adhesion molecule 70 TrkB 70 Tie2 70 steroidogenic 69 ERalpha 69 constitutively expressed 69 1alpha 69 TRAIL R2 69 extracellular domain 69 serine protease 69 alpha subunit 69 TGF ß1 69 Leydig cells 69 monocyte 69 TGF ß 69 Rab5 69 thymidylate synthase TS 69 transgenic mice expressing 69 endothelial nitric oxide synthase 69 guanosine 69 Extracellular 69 RNA polymerases 68 constitutively active 68 rRNA 68 NS3 68 protein tyrosine kinase 68 FGFR3 68 endonuclease 68 ERK signaling 68 microglial 68 TIMP 1 68 catenin 68 BMAL1 68 TNFalpha 68 Western blotting 68 p#Kip# 68 SOCS3 68 Upregulation 68 aggrecan 68 tumorigenicity 68 hydroxylase 68 CD# CD# 68 IL 1beta 68 cytidine 68 ectopic expression 68 #ß 68 umbilical vein 68 CD#c 68 upregulates 68 SCN5A 68 adipogenic 68 lymphangiogenesis 68 IFN g 68 HOTAIR 68 HIF 1alpha 68 carcinoembryonic antigen 68 HUVEC 67 Cathepsin B 67 PHD2 67 protein tyrosine phosphatase 67 acyltransferase 67 DNA methyltransferase 67 cytokines IL 67 mediated inhibition 67 transmembrane protein 67 transcriptional activation 67 carboxyl terminal 67 matrix metalloproteinase 67 5 HT2C receptor 67 VEGF receptor 67 isoenzyme 67 phosphorylated tau 67 cyclin dependent kinase 67 PDGFR 67 cyclooxygenase COX 67 bone marrow lymph nodes 67 androgen receptor AR 67 beta actin 67 receptor kinase 67 serine threonine kinase 67 5 hydroxytryptamine 67 tyrosine hydroxylase 67 CD# molecule 67 UCP1 67 PDGF B 67 c MYC 67 phosphorylates 67 amino terminal 67 glutamyl 67 Rap1 67 hypoxia inducible factor 67 adenosine diphosphate ADP 67 nitrotyrosine 67 vesicle fusion 67 FKBP# 67 chemokine receptor 67 #S rRNA 67 short hairpin RNAs 67 erythroid 67 transiently transfected 67 c Fos 67 catalytic subunit 67 interleukin IL 67 Macrophage 67 nitric oxide synthase NOS 67 TGF alpha 67 HIF 1α 67 TGF beta1 67 phosphatidylinositol 67 adipocyte 67 pathophysiological effects 67 interferon γ 67 Clusterin 67 lipoxygenase 67 polyamine 67 heterochromatic 67 Runx1 67 IRE1 67 RRM1 67 H#K#me# 66 dioxygenase 66 downregulate 66 inducible nitric oxide synthase 66 DNA methyltransferases 66 5 HT2A serotonin 66 cytosolic 66 OCT4 66 epithelial cells lining 66 costimulatory molecules 66 nitric oxide synthase 66 transcriptional activity 66 cytolytic activity 66 glucose transporter 66 TIMP 66 oncogenic transformation 66 avidin 66 cytokine receptors 66 IGF1R 66 GABAergic interneurons 66 MEK1 66 mRNA transcripts 66 inhibitory receptor 66 IL6 66 MAPK pathway 66 eNOS 66 cytoplasmic domain 66 coding genes 66 virulence genes 66 RT qPCR 66 thioredoxin 66 5alpha reductase 66 adhesion molecule 66 CaM 66 cytokine signaling 66 LRAT 66 effector memory 66 messenger ribonucleic acid 66 HEK# cells 66 COL#A# 66 transcriptional repressor 66 anterior pituitary 66 ligand receptor 66 VSV G 66 granzyme B 66 ACh 66 GLUT4 66 mitogen activated protein kinase 66 EphB4 66 1α 66 IL #p# 66 vWF 66 ESR1 66 trophoblast cells 66 MMP2 66 bone morphogenic protein 66 hematopoietic progenitors 66 colony stimulating factor 66 cytokeratin 66 DGAT1 66 caveolin 66 Eg5 66 monocytes macrophages 66 uPAR 66 methylenetetrahydrofolate reductase 66 PTPN# 66 PBMCs 66 MAP kinase 66 allogeneic epidermal 66 p# alpha [001] 66 ankyrin repeat 66 beta globin 66 Jhdm2a 66 Secretase 66 1beta 66 triacylglycerol 66 pyrimidine 66 PDE#A 66 GAPDH 66 Aâ 66 dimeric 66 HER2 HER2 66 chemoattractant 66 Sertoli cell 66 Phosphorylation 66 Mesenchymal 66 matrix metalloproteinases 66 elastase 66 HIF 1a 66 CD8 + 66 CXCL# 66 FGFs 66 HepG2 66 tyrosine phosphorylation 66 hepatoma 66 presynaptic 66 mRNA expression 66 cathepsin B 66 transgene expression 66 p# subunit 66 activin 66 iNOS 66 neurofilament 66 Androgen receptor 66 hematopoietic progenitor cells 66 protein tyrosine phosphatase 1B 66 KLF4 66 lymphoid cells 66 inverse agonist 66 TRAIL receptors 66 extracellular signal 66 IL 1ß 66 p# mitogen activated 66 potent inhibition 66 factor HGF 66 stably transfected 66 cisplatin resistant 65 deacetylation 65 dinucleotide 65 siRNA knockdown 65 S#A# [002] 65 hTERT 65 phosphoprotein 65 microvessel density 65 replicon 65 Protein Kinase C 65 cytochrome c oxidase 65 subcellular localization 65 CYP#A# CYP#D# 65 K ras mutations 65 phospholipase 65 deacetylase 65 FGF2 65 heterodimers 65 thyrotropin 65 Adrenergic 65 amino acid residue 65 endogenous ligands 65 retinoid X 65 toxic amyloid beta 65 Supplementary Fig 65 glucocerebroside primarily 65 prostaglandin E 65 ribosomal protein 65 CD# + [001] 65 lysates 65 fig. S1 65 BMP signaling 65 H#K# [002] 65 β1 65 fractional shortening 65 microRNA molecule 65 GNAQ 65 osteoblast 65 striatal 65 miR #a [002] 65 proteoglycan 65 ncRNA 65 cyclin dependent kinase inhibitor 65 homodimers 65 phospho 65 heme oxygenase 65 isoenzymes 65 globin genes 65 FUS1 65 FGFR4 65 alveolar epithelial cells 65 FasL 65 hypermethylated 65 phosphoinositide 65 homodimer 65 receptor tyrosine kinase 65 wildtype 65 F actin 65 downregulates 65 ,#,# [002] 65 Hypoxia Inducible Factor 65 striated muscle 65 Mutational 65 anionic backbone 65 coexpression 65 stem cell pluripotency 65 lyase 65 cyclic nucleotide 65 E#F# 65 glycosylated 65 β catenin 65 JAK STAT 65 autophagic 65 tetramer 65 Corynebacterium 65 interleukin IL -# 65 E cadherin expression 65 Fc receptor 65 tumor antigen 65 murine 65 immunoblotting 65 uracil 65 cytokine receptor 65 histone H3 65 ErbB1 65 Histone deacetylase 65 kinase domain 65 fibrin deposition 65 NOD SCID mice 65 serine proteases 65 tumor xenograft models 65 decarboxylase 65 methylation patterns 65 PIP3 65 myofibroblasts 65 factor PlGF 65 phosphate dehydrogenase 65 Fig. 1A 65 cystic fibrosis transmembrane conductance 65 chromatin modification 65 encodes protein 65 cyclic adenosine monophosphate cAMP 65 membrane proximal 65 T#M 65 CagA 65 lactate dehydrogenase 65 cell adhesion molecules 65 STAT1 65 microsomal 65 TTR gene 65 NKT cell 65 constitutively activated 65 osteoblastic 65 TET2 65 GluR1 65 mammaglobin 65 ptau 65 PDGF receptor 65 synthases 65 EGFR protein 65 isoprostane 65 telomerase reverse transcriptase 65 PTHrP 65 pro angiogenic 65 p#NTR 65 Angiotensin converting enzyme 65 tryptase 65 cardiac fibroblasts 65 Immunohistochemical staining 65 thymidine kinase 65 ABL1 65 glutamic acid decarboxylase GAD 65 glycolipid 65 BCL2 65 cytolytic 65 vacuolar 65 eotaxin 65 melanocyte 65 adrenoceptor 65 c fos 65 transferrin receptor 65 proto oncogene 65 immunostaining 65 angiotensinogen 65 urothelial 65 Signal transduction 65 reductase 65 HFE gene 65 centromeric 65 erythrocytes 65 Skeletal muscle 65 ADAMTS# 65 MT1 MMP 65 steroidogenesis 65 Abeta# 65 myocyte enhancer factor 65 Flt3 65 potent inducer 65 Cytotoxic T 65 miRNA expression 65 P2X 65 matrix metalloproteinases MMPs 65 Amino acid 65 haematopoietic 65 anaphase promoting complex 65 receptor mediated endocytosis 65 CD1d 65 collagen degradation 65 cytokines chemokines 65 adenylyl cyclase 65 splenocytes 65 Overexpression 65 deoxy 65 PECAM 65 t# c# CLA 65 ATP Adenosine 65 #S rRNA gene 65 gag pol 64 metabolizing enzyme 64 D aspartate 64 cytochrome b 64 bFGF 64 Annexin V 64 coreceptor 64 condensin 64 monocytic 64 coactivator 64 ß catenin 64 ectodomain 64 CD# ligand 64 P cadherin 64 regulated kinase 64 transmembrane receptor 64 CD#b 64 lysine residues 64 polycystin 64 plasminogen activator inhibitor 64 protein phosphatase 64 ERBB2 64 keratinocyte 64 downregulated 64 clonogenic 64 Wnt beta catenin 64 dehydrogenase 64 HDAC2 64 IL #E 64 p# MAPK 64 upregulating 64 Histone 64 Leydig cell 64 threonine 64 cAMP signaling 64 promoter methylation 64 cyclin B1 64 adrenocortical 64 tiny roundworm 64 colorectal tumor 64 secretase 64 CCL# 64 cathepsins 64 EF Tu 64 S6K 64 MMP# 64 acetyl CoA 64 cystic fibrosis transmembrane 64 NFκB 64 hippocampal neurons 64 FGF receptor 64 Sgk1 64 leukemic cell 64 heterozygotes 64 β galactosidase 64 antisense inhibition 64 gamma globin 64 genes encoding 64 ciliated 64 HER1 64 64 P selectin 64 p# p# 64 NFkB 64 glycosyltransferase 64 peripheral blood mononuclear 64 sarcomere 64 microglial activation 64 immunostimulatory 64 glutamic acid decarboxylase 64 TGF β 64 dependent protein kinase 64 apolipoprotein B 64 NO synthase 64 Ca2 + 64 #T# L1 64 EGFP 64 proapoptotic 64 axon guidance 64 Cytochrome 64 potent stimulator 64 alpha2 64 receptor CD# 64 GSTT1 64 radioligand 64 C#Y 64 glomerular 64 toxic beta amyloid 64 histone protein 64 motoneurons 64 GLUT1 64 metalloprotease 64 morphogen 64 miR# 64 ACC2 64 cytoplasmic tail 64 pyruvate kinase 64 nucleolin 64 monocyte chemotactic protein 64 forkhead 64 ERK1 64 immunoreactive 64 FGFR1 64 aspartyl 64 lymphoid tissue 64 apolipoprotein AI 64 myocytes 64 5 HT1A 64 lysosomal 64 myeloid derived 64 TGF β1 64 leucocytes 64 Smad3 64 defensin 64 contractile function 64 γ secretase 64 histone modifications 64 proteolytic cleavage 64 metabolizing enzymes 64 anti inflammatory cytokine 64 c Myb 64 pituitary hormone 64 TP# gene 64 tropomyosin 64 selectively binds 64 synthetases 64 Fig. 1D 64 covalently bound 64 caveolin 1 64 intronic 64 neural progenitor cells 64 somatostatin 64 transduced 64 null mice 64 ß amyloid 64 transfected cells 64 SWI SNF 64 cells transfected 64 noncoding 64 calcium calmodulin dependent 64 noncoding RNA 64 HER2 neu 64 thymidine 64 Hepatocytes 64 cholecystokinin CCK 64 proinflammatory cytokines 64 Dysregulation 64 succinate dehydrogenase 64 ENaC 64 CEACAM1 64 proximal tubule 64 posttranslational modification 64 interleukin IL -6 64 cAMP dependent 64 histone methylation 64 Tubulin 64 regulated kinase ERK 64 intracellular pH 64 Caveolin 1 64 cytochrome P 64 hypothalamic pituitary 64 intermediate filaments 64 CDK4 64 Nampt 64 oligomerization 64 urate oxidase 64 TMEM#B 64 phosphate S1P 64 integrin expression 64 Monocyte 64 immunoreactivity 64 protein tyrosine phosphatases 64 mitogen activated protein kinases 64 glyceraldehyde 3 64 Oncogenic 64 transgenic mouse model 64 vascular endothelial cells 64 DNMT1 64 Heterozygous 64 bronchoalveolar lavage fluid 64 SIRT2 64 selectively inhibited 64 ERK phosphorylation 64 AT1R 64 Î ² 64 RQ PCR 64 peroxidase 64 ribosomal DNA 64 MDR1 64 STAT4 64 TMPRSS2 ERG 64 matrix metalloprotease 64 muscarinic receptors 64 KLF2 64 intracellular proteins 64 transgenic mouse models 64 ALDH 64 transmembrane 64 microRNA #a 64 cytokine interleukin 64 ubiquitinated 64 LRP6 64 esterase 64 plasmacytoid dendritic cells 64 Epstein Barr Virus EBV 64 IFN gamma 64 BRAF protein 64 micronuclei 64 DU# [002] 63 MnSOD 63 phagocytosis 63 LPS induced 63 arachidonic acid AA 63 enkephalin 63 mouse fibroblasts 63 pro inflammatory cytokine 63 RhoA 63 lysophosphatidic acid 63 mononuclear cells 63 cortisol synthesis 63 HT 1A 63 Fas ligand 63 erythropoiesis 63 Interferon gamma 63 Src kinases 63 ChR2 63 IgG1 63 oligomeric 63 protein secreted 63 postsynaptic 63 vimentin 63 c MET 63 antibody antigen 63 glycogen synthase 63 lysosomal enzyme iduronate 63 lymphocyte activation 63 cysteine protease 63 EBNA1 63 IFNg 63 ligand induced 63 fast skeletal troponin 63 binding affinities 63 Foxp3 63 immunoregulatory 63 potently inhibited 63 NADPH 63 nicotinic receptor 63 #S proteasome 63 endothelial activation 63 syngeneic 63 #β HSD1 63 cyclin E 63 mitochondrial gene 63 regulates gene expression 63 MMP9 63 differential gene expression 63 Drosha 63 acetylcholine receptor 63 LRP5 63 mononuclear 63 carboxy terminal 63 Dopaminergic 63 TNFa 63 PI3K/mTOR 63 kD 63 gene encodes 63 MEK ERK 63 radiosensitivity 63 osteogenic 63 degranulation 63 prostaglandin E2 PGE2 63 Epidermal Growth Factor 63 FLT3 63 transfected 63 peptide receptor 63 ER alpha 63 transthyretin 63 Ki# 63 actin polymerization 63 endoglin 63 histone modification 63 N acetyl 63 sGC 63 phagocyte 63 IL 1β 63 oxidative phosphorylation 63 Notch receptor 63 VE cadherin 63 NKX#.# 63 Caspase 63 HER2 expression 63 ErbB4 63 vesicular stomatitis virus 63 BMP4 63 kidney urologic 63 Fig. 1d 63 downregulation 63 Catenin 63 MAPKs 63 vesicular monoamine transporter 63 adipokines 63 neuronal signaling 63 annexin V 63 HbF 63 colon carcinoma 63 astrocytic 63 mTOR mammalian target 63 PON1 63 survival motor neuron 63 intergenic regions 63 secretory pathway 63 receptor blocker 63 CTLs 63 allelic variants 63 FSHR 63 caspase activation 63 Fig. 4a 63 Vascular endothelial growth 63 noradrenergic 63 BoNT 63 vanA gene 63 Thyroid hormone 63 somatostatin receptors 63 beta amyloid peptide 63 glycolytic 63 adipogenesis 63 PGC 1α 63 surgically resected 63 immunodominant 63 amino acid residues 63 Supplementary Table 63 Prolactin 63 colorectal carcinoma 63 eIF4E 63 cytochrome c 63 dsRNA 63 antiproliferative activity 63 Fig. 1b 63 tyrosine kinase receptor 63 NFkappaB 63 Lymphocytes 63 overexpressing 63 CCR7 63 leukotriene B4 63 CHO cells 63 Fibroblast Growth Factor Receptor 63 CYP#A# [002] 63 sequence homology 63 Histologic 63 transthyretin TTR 63 mitotic progression 63 nAChR 63 TRPV4 63 ABCB1 63 Transcription factors 63 Hcrt 63 adrenal cortex 63 acetyltransferase 63 FDG uptake 63 serpin 63 myocyte 63 histone H3 lysine 63 MCF7 63 CDK inhibitor 63 Tissue Factor 63 antigenic peptide 63 siRNAs targeting 63 Wnt signaling pathway 63 costimulatory 63 glutamate transporter 63 proteinase 63 paralogs 63 HLA DR 63 subcellular compartments 63 T lymphocyte 63 uM 63 5 lipoxygenase 63 circulating endothelial 63 DR5 63 ephrin 63 adipose cells 63 cytoplasmic 63 Xenopus laevis 63 hydroxyproline 63 RIP1 63 clade B 63 transferase 63 NR2B subunit 63 gliosis 63 PPARg 63 Cre recombinase 63 thrombospondin 63 WT1 63 VEGF protein 63 KIAA# 63 ortholog 63 ERa 63 effector function 63 haemagglutinin 63 cytotoxicity assays 63 dendritic cells DCs 63 NMDAR 63 granulocyte 63 Monocytes 63 syntaxin 63 fig. S2 63 TRAIL R1 63 Endothelial Cells 63 PKC enzyme 63 potently inhibits 63 triphosphate 63 site directed mutagenesis 63 3' UTR 63 Immunohistochemical analysis 63 quantitative reverse transcriptase 63 fibronectin 63 isomerase 63 monomeric 63 nAChRs 63 hypothalamus pituitary 63 pancreatic endocrine 63 GLI1 63 Janus kinase 63 specific CD8 + 63 MLL2 63 glioblastoma cells 63 differentially regulated 63 gastric mucosa 63 CCR9 63 Akt activation 63 eIF2 63 redox sensitive 63 PC3 cells 63 actinin 63 desmin 63 synthetase 63 mice lacking 63 TNF receptors 63 interleukins 63 adenomatous polyposis coli 63 mitogenic 63 c Src 63 CpG island 63 desaturase 63 Stat1 63 germinal center 63 Dpp 63 C#T [002] 63 hepatic glucose production 63 MYCN 63 dephosphorylation 63 retinoic acid receptor 63 PKC delta 63 beta globin gene 63 TSLP 63 basic fibroblast 63 disulfide bond 63 arcuate nucleus 63 non coding RNA 63 activated microglia 62 beta adrenergic receptors 62 NF κB 62 #β estradiol 62 triiodothyronine 62 ribonucleic acid RNA 62 neuronal nitric oxide synthase 62 hydrolases 62 junctional 62 SMAD4 62 Platelet Derived Growth 62 induces apoptosis 62 Epithelial 62 Figure 1C 62 cellularity 62 JAK2 enzyme 62 azacytidine 62 galectins 62 HDAC6 62 chemokine receptors 62 CD# expression [001] 62 Arp2 3 62 murine model 62 mineralocorticoid 62 PPARgamma 62 ribonuclease 62 Fig. 1c 62 actin binding 62 hyperplastic 62 pancreatic islet beta 62 immunofluorescence microscopy 62 TNFR1 62 Ab# 62 dehydrogenases 62 B lymphocyte 62 soluble TNF receptor 62 fatty acid oxidation 62 RTKs 62 sphingomyelin 62 Phenylalanine 62 chondrocyte 62 receptor gene 62 histone acetylation 62 GPR# [002] 62 CD# expression [002] 62 raphe 62 CXCR2 62 tRNA synthetase 62 major histocompatibility complex 62 leptin signaling 62 IGFBP2 62 HuR 62 prostate epithelial cells 62 nicotinamide adenine dinucleotide 62 bronchial epithelial cells 62 cell nuclei 62 intestinal epithelium 62 leukocyte adhesion 62 contractile 62 calcium homeostasis 62 RANTES 62 pDCs 62 induced apoptosis 62 cell receptor TCR 62 Nod1 62 At#g# 62 myeloid 62 muscarinic receptor 62 glycogen synthase kinase 62 missense mutations 62 basal forebrain 62 HCV replicon 62 enzymatic pathways 62 hexose 62 diphosphate 62 SOD2 62 PU.1 62 cells overexpressing 62 pRb 62 c myc 62 assay detects 62 erythrocyte 62 miR #a [001] 62 MyoD 62 CD#L 62 splice variants 62 SETDB1 62 UCP2 62 Sp1 62 synuclein 62 ERK2 62 extracellular domains 62 GH secretion 62 macrophage colony stimulating 62 inhibin B 62 microcephalin 62 TOP2A gene 62 hypoxia induced 62 CD3 + 62 RNA splicing 62 anti CD3 62 vasoactive 62 evolutionary conserved 62 Beta catenin pathway 62 metabolite concentrations 62 heme oxygenase 1 62 CYP #D# 62 selective inhibition 62 serotonin synthesis 62 constitutively