perforin

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(Click for frequent words.) 60 GSK3 60 bacterial enzyme 60 proteasomes 59 palytoxin 59 proton pump 58 intracellular pathogens 58 tumor suppressor protein 58 macrophage cells 57 antimicrobial peptides 57 TRIM5a 57 vascular endothelial cells 57 protein fragment 57 pRb 57 HCV replication 57 primary cilia 57 TRIM# 56 phagosome 56 TAp# 56 intracellular bacteria 56 invading microorganisms 56 neuroblastoma cells 56 Wnt signaling pathway 56 BMP4 56 secrete proteins 56 anthrax toxin 56 GLUT4 55 elastase 55 E1A 55 TGF β 55 ryanodine receptor 55 receptor molecule 55 tenascin C 55 plasminogen 55 protease enzyme 55 phagocyte 55 APOBEC3G 55 Vpu 55 viral proteins 55 immune cells 55 chitinase 55 intracellular proteins 55 VEGF receptor 55 TRAF6 55 hedgehog pathway 55 IKKa 55 Skp2 55 C EBP alpha 55 metalloproteinases 55 Nedd4 55 HCMV 55 RUNX3 55 palladin 55 adhesion molecule 55 PKM2 55 Wnt pathway 55 CK2 55 naturally occurring enzyme 55 NK cells 55 Akt3 54 cyclic AMP cAMP 54 virally infected cells 54 calcineurin 54 invading microbes 54 bacterial toxin 54 SIRT2 54 cellular signaling pathways 54 uPAR 54 MT1 MMP 54 naturally occurring molecule 54 SGK1 54 cellular metabolism 54 PIP2 54 ligases 54 anthrax toxins 54 EphB2 54 phagocytosis 54 NFkB 54 pyruvate kinase 54 LED# 54 PP2A 54 caveolae 54 defensins 54 hematopoetic stem cells 54 bacterial enzymes 53 microglial 53 trypanosomes 53 IKKß 53 androgen receptors 53 PKC alpha 53 intracellular signaling 53 FGFs 53 SOD1 53 EphA2 53 cathepsins 53 lectins 53 EGF receptor 53 macrophage 53 peroxisomes 53 MDM2 53 IKK2 53 beta adrenergic receptors 53 amyloid proteins 53 PrP 53 c MYC 53 HDAC2 53 Alu RNA 53 Rab5 53 CXCR4 receptor 53 cAMP signaling 53 astrocyte cells 53 Math1 53 sortilin 53 CD#L 53 CXCR2 53 cofilin 53 eotaxin 53 podocytes 53 ubiquitin ligase 53 focal adhesion kinase FAK 53 IGFBP7 53 p# MAPK 53 outer membrane proteins 53 SIRT6 53 caveolin 1 53 catenin 53 TGF ß 53 PIP3 53 Rad# 53 GAPDH 53 PI3 kinase pathway 53 fibrocytes 53 ubiquitylation 53 MAPKs 53 HSP# 53 beta amyloid peptide 53 p# subunit 53 glioblastoma cells 52 neurite outgrowth 52 Rb protein 52 M.tb 52 Src kinases 52 osteocalcin 52 STAT3 52 membrane receptors 52 CD# protein 52 integrin 52 Smurf1 52 integrins 52 chromatin remodeling complex 52 Mcl 1 52 tetherin 52 alveolar macrophages 52 synapse formation 52 S#A# [002] 52 ERK2 52 granzyme B 52 Immunohistochemical analysis 52 Nrf2 52 intracellular 52 mTORC1 52 Fc receptors 52 mammaglobin 52 tumor cells 52 FGFR1 52 suppressor cells 52 BACE1 52 melanocyte 52 PAK1 52 CatB 52 SATB1 52 antioxidant enzymes 52 TRIM5 52 PHD2 52 autophagic 52 CCL# 52 TGF beta pathway 52 molecule 52 mutant huntingtin 52 transferrin receptor 52 gut mucosa 52 calpain 52 ATF2 52 Vif 52 CD8 cells 52 arginase 52 metalloproteases 52 coreceptor 52 cytotoxic T lymphocytes 52 mRNA translation 52 antimicrobial peptide 52 C5aR 52 VEGFR1 52 LRP1 52 RKIP 52 MAP kinase 52 phosphorylates 52 PPARg 52 nestin 52 XBP1 52 PPAR alpha 52 Cytotoxic T 52 nicotinic receptors 52 misfolded protein 52 proteins 52 actin cytoskeleton 52 STAT1 52 NKT cell 52 HOTAIR 52 prostaglandin E2 52 TNFa 52 calcium ion 52 paxillin 52 IL 1β 52 neuromuscular junction 52 myeloid derived 52 PTP1B 52 porphyrins 51 pro apoptotic proteins 51 gene p# 51 NF kappaB 51 LKB1 51 MAP kinases 51 cyclophilin D 51 cdk5 51 MIF protein 51 hypoxia inducible factor 51 p#Kip# 51 acetylcholine receptors 51 bacterial toxins 51 FOXO3a 51 oncomodulin 51 RANK ligand 51 caspases 51 messenger molecule 51 TGF ß1 51 virulence genes 51 glioma cells 51 PKD1 51 BMP signaling 51 micro RNAs 51 RAD# [001] 51 myeloma cells 51 proteases 51 A3G 51 EF Tu 51 neural progenitor cells 51 cyclic AMP 51 cyclic GMP 51 miR #b [002] 51 SWI SNF 51 enzyme 51 Notch1 51 riboswitches 51 glucocorticoid receptor 51 nucleolus 51 IFNg 51 beta catenin 51 metabolic enzymes 51 PPAR gamma 51 UCP2 51 Kv#.# 51 microparticles 51 CTLA 4 51 interferon pathway 51 CD8 T cells 51 bacterial virulence 51 S. mutans 51 mutated protein 51 β catenin 51 Notch signaling 51 BCL6 51 Siglec 8 51 protein interleukin 51 ERK1 2 51 Wnt proteins 51 syntaxin 51 Wnt signaling 51 alpha synuclein 51 Prox1 51 miR #a [002] 51 apoptotic pathway 51 microvesicles 51 ceramide 51 transgenic rats 51 chemokine receptor 51 serotonin receptor 51 NPC#L# 51 oncoprotein 51 breast cancer metastasis 51 Monocytes 51 TGF beta1 51 phagocytes 51 ACE2 51 LDL receptor 51 mesenchymal cells 51 uPA 51 TB bacterium 51 gp# [002] 51 NFκB 51 mutant protein 51 PGE2 51 effector cells 51 ubiquitination 51 IL 1beta 51 receptor molecules 51 trophoblasts 51 enzyme telomerase 51 naturally occurring protein 51 nNOS 51 VEGF 51 activin 50 costimulatory 50 cardiac fibroblasts 50 interleukins 50 amyloid ß 50 microbial invaders 50 soluble receptor 50 AMPA receptor 50 ADDLs 50 S#K# 50 MAPK 50 malonyl CoA 50 melanoma tumors 50 HDACs 50 PI3 kinase 50 Polycomb 50 cathepsin B 50 adaptive immunity 50 TSLP 50 T lymphocytes 50 SIRT3 50 microRNA molecules 50 normal prion protein 50 Cdc# 50 retinoic acid 50 osteoblast 50 autoreactive T cells 50 clusterin 50 constitutively 50 secretory pathway 50 Mdm2 50 p# pathway 50 fibrogenesis 50 malaria parasite Plasmodium falciparum 50 NMDA receptors 50 telomerase gene 50 TLR2 50 invadopodia 50 effector proteins 50 thioredoxin 50 integrin alpha 4 50 lysosome 50 orexin 50 vascular endothelial 50 invading pathogen 50 protein kinase C 50 glucocorticoid receptors 50 DGAT1 50 fatty plaques 50 opiate receptors 50 ARF1 50 MEF2 50 molecular pathway 50 microglial cells 50 genotoxic stress 50 cardiolipin 50 eNOS 50 TNFα 50 inflammatory cytokine 50 miR# 50 glutamate receptors 50 c myc 50 RANKL 50 HER2 receptors 50 intronic 50 monocyte 50 antisense RNA 50 epithelial cell 50 glycosyltransferase 50 cyclins 50 cell cytoplasm 50 adenylate cyclase 50 telomerase reverse transcriptase 50 serine proteases 50 WT1 50 Robo4 50 phospholipase C 50 ABCA1 50 p# [001] 50 ACAT2 50 effector molecules 50 cell signaling pathway 50 CIB1 50 CXCL# 50 Foxp3 50 Stat3 50 pDCs 50 Oncogenic 50 N Myc 50 protease enzymes 50 telomerase enzyme 50 IRF5 50 cellular pathways 50 E selectin 50 microvascular endothelial cells 50 intestinal epithelial cells 50 tumorigenesis 50 ATPase 50 cells 50 Akt1 50 amyloid protein 50 TNF α 50 osteoclasts 50 P. gingivalis 50 lipid rafts 50 CLL cells 49 tyrosine kinase 49 CB1 receptors 49 Rap1 49 TSP1 49 fusion protein 49 Helicobacter 49 interferon gamma 49 amyloids 49 proteasome 49 T lymphocyte 49 TNFalpha 49 matrix metalloproteinases 49 protease 49 #S proteasome 49 biochemical pathway 49 SREBP 49 Th# cells 49 tumor suppressor 49 c Myc 49 RecA 49 Wnt 49 MetAP2 49 Th1 type 49 inducible 49 FGF# 49 P selectin 49 P glycoprotein 49 mutant proteins 49 mesothelin 49 adrenergic receptors 49 beta1 integrin 49 Hsp# [001] 49 galectin 49 cannabinoid receptors 49 neutralizing antibody 49 beta amyloid protein 49 apoptosis inducing 49 enzymatic activity 49 signaling pathway 49 receptor protein 49 cancerous cells 49 protein 49 tumor microenvironment 49 49 NF κB 49 tau proteins 49 biotinylated 49 p#NTR 49 CCR5 receptor 49 phosphorylate 49 dsRNA 49 Langerhans cells 49 enzymes 49 gamma interferon 49 TNF receptors 49 uninfected cells 49 trypsin 49 EGFR pathway 49 NRG1 49 p# protein 49 OCT4 49 apical membrane 49 Sertoli cells 49 bacterial invaders 49 tumor suppressor p# 49 PDGFR 49 MDSCs 49 TGFbeta 49 antibody mediated 49 acyltransferase 49 protein p# 49 PrPSc 49 amyloid beta protein 49 Th1 cells 49 IGF 1R 49 CXCL5 49 phagocytic cells 49 platelet activating 49 tau protein 49 NF kappa B 49 Dpp 49 neural stem 49 innate immunity 49 virulence factors 49 Vps# 49 Smad3 49 presynaptic 49 tumor suppressors 49 coexpression 49 molecules 49 JAK2 enzyme 49 macrophages 49 fatty acid synthesis 49 transferase 49 TORC1 49 endogenous cannabinoids 49 NMDA receptor 49 E cadherin 49 pyrophosphate 49 acetyltransferase 49 cyclin D1 49 Pax6 49 disulfide bond 49 androgen receptor 49 PGC1 49 cysteine 48 CTLs 48 EZH2 48 amyloid deposits 48 tumor antigens 48 iNOS 48 leukocyte recruitment 48 EphB4 48 signaling pathways 48 aT cell 48 apoptotic 48 enterocytes 48 CD4 + T lymphocytes 48 lysosomal 48 innate immune 48 MMP2 48 oxidized lipids 48 GRK2 48 basophils 48 MALAT1 48 TGF beta 48 androgen receptor AR 48 histone deacetylases 48 toxic beta amyloid 48 Treg cells 48 fibronectin 48 lysates 48 membrane protein 48 innate immune response 48 diseased cells 48 diffusible 48 Notch pathway 48 tumor angiogenesis 48 4E BP1 48 Ku# 48 prion proteins 48 Stat1 48 cell signaling pathways 48 Oct4 48 S1P 48 SUMOylation 48 Wnts 48 peptide antigens 48 TGF b 48 mammary cells 48 Pdx1 48 signaling molecule 48 ADAM# 48 abzymes 48 acetyl CoA 48 CaM 48 intracellular signaling pathways 48 vesicle 48 RhoA 48 NAD + 48 erythroid 48 estrogen receptor alpha 48 p# activation 48 Notch receptors 48 Purkinje cell 48 beta amyloid plaques 48 KLF# 48 divide uncontrollably 48 PAX5 48 breast epithelial cells 48 IGFBP 3 48 urease 48 morphogen 48 hyperactivation 48 Th2 immune 48 histone modifications 48 angiotensin II 48 PPAR delta 48 endocytosis 48 Src 48 CCR5 receptors 48 pericytes 48 innate immune system 48 Immune cells 48 SOCS3 48 hematopoietic cells 48 bile acid 48 leukemic cells 48 insulin secreting cells 48 TORC2 48 hippocampal neurons 48 dimeric 48 intestinal epithelium 48 superoxide dismutase 48 senescent cells 48 sphingomyelin 48 glycoproteins 48 lymphoid tissue 48 mutant SOD1 48 PEDF 48 adhesion molecules 48 autophagy 48 Smoothened 48 SIRT1 48 enteric nervous 48 NKT cells 48 Nrf2 pathway 48 SH2 B 48 anti inflammatory cytokine 48 RGS2 48 integrin receptors 48 allergic inflammation 47 Th2 cytokines 47 p# gene 47 RNA molecule 47 neurones 47 granulocytes 47 messenger RNAs 47 cells secrete 47 splenocytes 47 p# MAP kinase 47 basal lamina 47 LXRs 47 protein kinase 47 bradykinin 47 PPARγ 47 TGFb 47 cAMP 47 HER2 protein 47 peptides 47 lipid synthesis 47 Cajal bodies 47 NF kB 47 BRAF gene 47 CXCR4 47 mucosal immunity 47 protein synthesis 47 Kv#.# channels 47 cytosol 47 NR1 47 47 chaperone protein 47 HDAC 47 Lymphocytes 47 tumor vasculature 47 chemokine 47 receptor CD# 47 HER2 receptor 47 tumor suppressor gene 47 digesting enzyme 47 Shiga toxin 47 lipases 47 enzyme phosphodiesterase 47 renal fibrosis 47 vitamin D receptors 47 M1 muscarinic 47 induced apoptosis 47 antigen presenting cells 47 bryostatin 47 proto oncogene 47 Th# 47 receptor gamma 47 stellate cells 47 leptin signaling 47 nucleolar 47 neuronal cell 47 eukaryotic cells 47 CD#b 47 thyroid hormone receptor 47 galectins 47 cardiac myocytes 47 EGFP 47 misfolded 47 hedgehog signaling 47 cytokines 47 progranulin 47 hormone ghrelin 47 nicotinic acetylcholine receptor 47 Hedgehog pathway 47 IRAK1 47 adipose cells 47 AMPA receptors 47 BCL#A 47 neurone 47 dendritic cells 47 OGG1 47 sporozoites 47 GSK3B 47 endosome 47 keratinocyte 47 lymphoid cells 47 alpha Gal 47 estrogen receptors 47 effector T 46 Annexin V 46 MHC molecules 46 mRNA molecules 46 IFN γ 46 beta defensins 46 glutathione S transferase 46 polymorphonuclear leukocytes 46 HLA molecules 46 beta amyloid 46 reactive oxygen 46 proteolysis 46 superantigens 46 Plasmodium 46 focal adhesions 46 mammalian cells 46 glycoprotein 46 eosinophil 46 mitochondria 46 glutathione 46 microRNAs 46 cytokine secretion 46 PGC 1alpha 46 lymphoid organs 46 Akt 46 FAK 46 ZFN modified cells 46 cytokine 46 malignant cells 46 IFN gamma 46 adherens junctions 46 Myc 46 antigen receptor 46 GTPase 46 invading pathogens 46 innate immune responses 46 neural cells 46 Neutrophils 46 pancreatic cells 46 immature dendritic cells 46 activated macrophages 46 antibodies 46 malaria parasite 46 viral RNA 46 EGFRvIII 46 molecular pathways 46 mice lacking 46 NF kB pathway 46 effector functions 46 hypermethylation 46 PI3K pathway 46 outer membrane 46 sirtuin 46 mesenchymal stem cells MSCs 46 glutathione GSH 46 MAPCs 46 DMT1 46 M1 macrophages 46 neutrophil 46 plasmacytoid dendritic cells 46 signaling molecules 46 midgut 46 mRNAs 46 IL# [001] 46 1alpha 46 autoreactive 46 netrin 1 46 TAT2 46 Stat5 46 virions 46 dendritic cells DCs 46 tumor suppressor genes 46 inflammasome 46 tumor antigen 46 scavenger cells 46 Fig. 1C 46 C5a 45 amyloid beta 45 messenger RNAs mRNAs 45 erythropoiesis 45 P2X 45 leukocytes 45 lymphocytes 45 amyloid beta proteins 45 mononuclear 45 IgG antibodies 45 B lymphocytes 45 phosphorylated 45 amyloid 45 activated lymphocytes 45 endothelial progenitor cells 45 Fibroblasts 45 receptor 45 antiproliferative activity 45 angiogenesis 45 malarial parasites 45 Th2 cells 45 neutrophils 45 Neural stem cells 45 apoptotic cells 45 leukocyte 45 antibody IgE 45 intestinal mucosa 45 FOXO1 45 lymphoid tissues 45 eicosanoids 45 1beta 45 erythrocytes 45 inhibitory neurons 45 receptor proteins 45 eIF2 45 Ca2 + 45 neurotrophins 45 Fc receptor 45 paracrine 45 NADPH oxidase 45 adaptive immune 45 pancreatic islet 45 CCL5 45 transmembrane domain 45 neuronal stem cells 45 dendritic cell 45 leucocytes 45 mutant worms 45 CaMKII 45 neurofilament 45 glutamine synthetase 45 STIM1 45 supramolecular assembly 45 goblet cells 45 Wwox 45 endothelial cell 45 protein kinases 45 TLR9 45 AMPK 45 osteopontin 45 polymerases 45 monocyte macrophage 45 telomerase 45 β galactosidase 45 neurotransmitter glutamate 45 epithelial tissues 45 integrin mediated 45 glutamate 45 antibody 45 hepcidin 45 effector memory 45 Phosphorylation 45 amyloid plaque 45 chemokine receptors 45 germinal centers 45 mice 45 plasma membrane 45 Secretase 45 focal adhesion 45 Notch receptor 44 TRPV4 44 misfolded proteins 44 lipopolysaccharide 44 caspase 44 retinal cells 44 transmembrane 44 glycolipids 44 RNA molecules 44 bacterial 44 TNFR 44 astrocytes 44 co stimulatory molecules 44 phage 44 Microtubule 44 astrocyte 44 Dendritic cells 44 gluconeogenesis 44 TUNEL 44 Tumor cells 44 immunological 44 TH1 cells 44 PTEN gene 44 CD4 + cells 44 oncogenes 44 fibroblast 44 viral antigens 44 TNF alpha 44 TH# cells 44 pyramidal neurons 44 PU.1 44 JAK3 44 interleukin 44 myostatin 44 transcription factor 44 epicardium 44 CD# receptor 44 viral particles 44 RNA polymerase II 44 vWF 44 inactivating 44 leukaemic cells 44 phosphatidylinositol 44 HBx 44 mononuclear phagocytes 44 RAP# 44 scavenger receptor 44 MMPs 44 intestinal lining 44 binding proteins 44 SIRT1 gene 44 HSCs 44 keratinocytes 44 leukocyte adhesion 44 Fig. 1A 44 CCR7 44 inhibitory 44 Tubulin 44 Nampt 44 monocytes 44 Macrophages 44 vasculature 44 PAR1 44 surface plasmon 43 yeast cells 43 eosinophils 43 transcription factors 43 exosomes 43 antigen presenting cell 43 bile acids 43 Tregs 43 myofibroblasts 43 epitope 43 diseased tissues 43 angiogenic 43 amyloid plaques 43 deficient mice 43 serotonin receptors 43 CB2 receptors 43 Aldosterone 43 nerve cells 43 neoplastic cells 43 PlGF 43 angiotensin 43 Th2 43 SH2 domain 43 glial cells 43 mesenchymal cell 43 glycosylated 43 chemotaxis 43 KSHV 43 stromal cells 43 Neu5Gc 43 lipids 43 RNAs 43 PBMCs 43 incretin hormones 43 CD8 T 43 junctional 43 myeloid cells 43 GTPases 43 mRNA 43 inflammatory cytokines 43 nitric oxide 43 fibroblast cells 43 chemokines 43 myelin sheath 43 skeletal muscle cells 43 hair follicle stem cells 43 acetylcholine 43 huntingtin protein 43 EP4 43 donor marrow 43 pro inflammatory cytokines 43 bacterium 43 tumors 43 endothelial cells 43 glutamine 42 Th1 42 phages 42 Catenin 42 antitumor immune 42 suppressor 42 oncoproteins 42 folate receptor 42 cytotoxic T 42 haematopoietic stem cells 42 cell membrane 42 leukemic stem cells 42 epithelial cells 42 receptors 42 Leishmania parasite 42 isoleucine 42 hyperactivated 42 malaria parasites

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