Related by context. Frequent words. (Click for all words.) 79 pharmacokinetics 72 pharmacokinetic 70 pharmacokinetic profile 67 tolerability 67 safety tolerability 66 immunogenicity 65 pharmacodynamic 65 dose escalation trial 64 Phase Ib 64 GRN#L 64 placebo controlled 63 dose escalation study 63 single ascending dose 62 dosing regimens 62 Phase 2a trial 62 dose escalation 61 pharmacokinetic properties 61 Phase IIa trial 61 antitumor activity 61 Phase 1b 61 tolerability profile 61 Phase 2a clinical 61 blind randomized placebo 61 tolerated dose MTD 61 blind placebo controlled 60 efficacy 60 label dose escalation 60 Phase IIa clinical 60 antiviral activity 60 Phase 2b study 60 Phase 2b clinical 60 double blind placebo 60 multiple ascending dose 60 PF # [001] 60 CTCE 60 ISIS # 59 Phase IIb clinical 59 randomized placebo controlled 59 investigational oral 59 phase IIb 59 randomized double 59 BAY #-# 59 HGS ETR1 59 active metabolite 59 randomized clinical 59 bosentan 59 blind randomized 59 CYT# 58 multicenter randomized double 58 tgAAC# 58 dose regimen 58 Phase IIa 58 relapsing remitting multiple sclerosis 58 Phase III clinical 58 dose limiting toxicities 58 preclinical studies 58 Secondary endpoints 58 orally administered 58 dosing schedules 58 allopurinol 58 clinical trial 57 mg dose 57 Phase IIb trial 57 monotherapy 57 CA4P 57 belinostat 57 mg BID 57 CERE 57 ISENTRESS 57 immunomodulatory 57 antisense drug 57 plasma concentrations 57 vivo 57 IMGN# 57 protease inhibitor 57 RDEA# 57 antitumor 57 Debio 57 Secondary endpoints include 56 eltrombopag 56 bortezomib 56 LEVADEX 56 MGCD# [001] 56 pivotal Phase III 56 vandetanib 56 Phase 2b trial 56 placebo controlled trials 56 ARRY 56 docetaxel 56 oral bioavailability 56 adalimumab 56 bioavailability 56 FTY# 56 mitoxantrone 56 CK # 56 pivotal Phase 56 Pharmacokinetics 56 glucose lowering 56 investigational drug 56 bevirimat 56 RG# [001]