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(Click for frequent words.) 65 epothilone 64 vitamin D analogs 63 proteasome inhibitors 63 small molecule activators 63 MEK inhibitors 62 Fleximer 62 catalytic antioxidant compounds 62 biologic therapeutics 62 molecularly targeted 62 LNP formulations 62 Anavex #-# 62 optical biosensors 61 Symadex 61 Kinase inhibitors 61 P#X# 60 therapeutic modality 60 renin inhibitors 60 VDAs 60 CCX# 60 HuLuc# 60 antitumour 60 siRNA therapeutics 60 Adnectin 60 SARMs 60 prostanoid 60 HCV protease inhibitors 60 maturation inhibitors 60 opioid antagonists 60 CBLC# 60 peptidomimetic 60 antiangiogenic agents 59 XmAb# 59 Anticalins R 59 anticoagulant reversing agent 59 siRNA therapeutic 59 selective inhibition 59 Nanobody ® 59 anti angiogenic drugs 59 orally bioavailable 59 novel peptide 59 histone deacetylase HDAC inhibitors 59 stapled peptides 59 antisense oligonucleotide 59 polyketides 59 KL4 surfactant 59 therapeutic monoclonal antibody 59 TriRima 59 EP #R 59 Pentad TM 59 small molecule PEGylation 59 vascular disrupting agents 59 synthetic siRNA 59 acetylcholinesterase AChE 58 anticancer agent 58 synthetic retinoid 58 insulin sensitizers 58 Nanobodies 58 pharmacologic approaches 58 oncolytic vaccine 58 histone deacetylase inhibitors 58 liposome formulations 58 Bioral 58 LHRH antagonists 58 metaglidasen 58 dAbs 58 rxRNA 58 immunotherapeutics 58 selective inhibitors 58 sd rxRNA 58 epigenetic therapeutics 58 Fc fusion protein 58 protein tyrosine phosphatase 58 antithrombotic agents 58 ZFP TF 58 vascular disrupting agent 58 transfection reagents 58 anticancer agents 58 orally bioavailable mimics 58 biomarker identification 58 protein kinase inhibitors 58 HepDirect prodrug 58 PORxin TM 58 affinity antibodies 58 CRAC channel 58 SiMoA 58 macrolide antibiotics 58 PI3K/mTOR 58 multitargeted 58 beta Estradiol 58 therapeutic monoclonal antibodies 58 anti mitotic 58 highly selective endothelin 58 Peptidomics 58 JAK inhibitors 58 histone deacetylase HDAC 58 Mipomersen 58 RONDEL ™ 58 HepDirect R 58 Squalamine 58 platinum chemotherapeutic 58 immunotherapeutic agent 58 TLR agonists 58 Enkephalin 57 multiplexed assays 57 enzyme inhibitors 57 chemical entities NCEs 57 nano encapsulation technology 57 monoclonal antibody therapeutics 57 anticancer therapeutics 57 anti CD3 57 mGluR2 NAM 57 #beta HSD1 57 Fleximer R 57 PPAR gamma agonists 57 Metallophile ™ Technology 57 immunosuppressive regimens 57 ENMD # 57 peptidic 57 mimetics 57 Isis antisense 57 direct thrombin inhibitors 57 BCR ABL inhibitors 57 MDRNA proprietary 57 Hsp# inhibition 57 PARP inhibitors 57 PDE4 inhibitor 57 HSP# inhibitor 57 ATL/TV# 57 chemotherapeutics 57 TRV# [001] 57 mTOR inhibitors 57 polymer coatings 57 antifolate 57 pegylation 57 selective kinase inhibitors 57 tkRNAi technology 57 molecular biomarkers 57 delta isoform 57 Transfection Reagent 57 RNAi compounds 57 TOF TOF 57 NovaBay Aganocide compounds 57 proprietary PEGylation 57 Smac mimetic 57 Pepducin 57 U1 Adaptors 57 HDAC inhibitors 57 nucleosides 57 drug zotarolimus 57 AngioJet System 57 exon skipping 57 CB1 antagonists 57 proprietary LNA 57 protein biochip 57 AKT inhibitor 56 Photodynamic therapy PDT 56 CYT# potent vascular disrupting 56 sodium glucose cotransporter 56 insulin analogs 56 kinase inhibitors 56 rxRNA ™ compounds 56 HSP# inhibitors 56 COMT inhibitors 56 liposomal formulation 56 cyclin dependent kinase inhibitor 56 kinase inhibition 56 Curaxin 56 intravenous cyclophosphamide 56 polyketide 56 antisense drug 56 quinolone 56 selective androgen receptor modulators 56 disease modifying 56 vorinostat 56 multiplex assay 56 dSLIM 56 anticancer therapies 56 LentiVector 56 AEG# 56 pharmacologic agents 56 Factor VIIa 56 AMPAKINE 56 Anticalins 56 antiangiogenic 56 KL4 Surfactant 56 selective orally bioavailable 56 antiapoptotic 56 ImmuneY2 56 monoclonal antibody therapies 56 Cyclosert TM 56 oral taxane 56 dasatinib Sprycel 56 XmAb 56 XP #L 56 Epothilones 56 preclinically 56 Hemopurifier ® 56 antithrombotic 56 antiplatelet therapies 56 synthetic siRNAs 56 small molecule tyrosine 56 therapeutic peptide 56 generation antisense 56 siRNAs targeting 56 proprietary Biochronomer 56 Azedra 56 buccal delivery 56 adrenergic regulation 56 antisense oligonucleotides 56 PDGF receptor 56 cleavable linker 56 Cdc7 56 VitiGam 56 brain penetrant 56 Alfacell proprietary ribonuclease 56 pulsed electromagnetic field 56 Tasimelteon 56 HGS# 56 histone methyltransferases HMTs 56 peptide conjugated 56 metabolite profiling 56 NNRTIs 56 SGLT Inhibitors 56 HDAC inhibition 56 Protein Kinase C 56 NNR Therapeutics 56 rxRNA compounds 56 NTDDS 56 Intravenous CP 56 SGLT2 inhibitors 56 DXL TM 56 immunomodulation 56 HDAC6 56 taxane derivative 56 vinca alkaloid 56 HIV maturation inhibition 56 PET tracers 56 UCOE 56 TLR Therapeutics 56 selective antagonists 56 AAV vectors 55 proprietary encapsulation 55 antimitotic 55 DOS# 55 LTQ Orbitrap 55 antibody humanization 55 Locked Nucleic Acid LNA 55 Stapled Peptide 55 Archexin 55 Biomerk Tumorgrafts 55 patented Bioral R nanocochleate 55 Litx 55 PDE4 inhibitors 55 proteasome inhibitor 55 selective antagonist 55 mGluR5 antagonist 55 SERCA2a 55 druggable targets 55 nitric oxide donating 55 photoactivation 55 VEGF inhibitors 55 lipid nanoparticles 55 immunosuppressive 55 Liposomal 55 AAV vector 55 bioabsorbable polymer 55 Ambrotose ® complex 55 Hsp# inhibitors 55 Revimmune 55 FD SOI 55 otelixizumab 55 Affibody ® molecules 55 receptor tyrosine kinase inhibitor 55 iRGD 55 Interferon beta 55 coronary stent merged 55 metalloenzymes 55 SERMs 55 bifurcation stent 55 XIENCE PRIME 55 chemically modified siRNA 55 Regado 55 resolvins 55 TARIS 55 ganaxolone 55 topical formulations 55 Bendavia 55 AclarusDx ™ 55 biased ligands 55 BFPET 55 Nanobody 55 immunotherapeutic approaches 55 chemopreventive agents 55 iPSC 55 calcineurin inhibitors 55 ArQule Kinase Inhibitor Platform 55 Aptamer 55 CCR9 antagonist 55 Vidofludimus 55 molecular abnormalities 55 pharmacological treatments 55 OncoVEX 55 nucleoside analogue 55 Zysolin TM 55 camptothecin 55 insulin sensitizer 55 ProSavin 55 #ME# 55 Acetylon 55 rHuPH# enzyme 55 small molecule inhibitors 55 ErbB3 HER3 55 galectin 55 x ray optics 55 isoform selective 55 SGLT inhibitors 55 Smac mimetics 55 peptide antigens 55 nanomedicines 55 PI3K inhibitors 55 nanomotors 55 patterning technique 55 Calcineurin inhibitors 55 L L Glutamine 55 cancer immunotherapies 55 patented Bioral 55 therapeutic mAbs 55 DACH platinum 55 punctal plug delivery 55 sirtuin therapeutics 55 tubulin inhibitor 55 Pimavanserin 55 chemotherapeutic drug 55 peptide therapeutics 55 MAXY VII 55 Photodynamic therapy 55 immunotherapeutic vaccine 55 NexACT ® 55 SNALP formulation 55 PSN# [002] 55 accommodating IOL 55 Curaxins 55 Anticalins ® 55 Cerashield ™ 55 prodrugs 54 allosteric modulation 54 mineralocorticoid receptor 54 renin inhibition 54 oxazolidinone 54 antisense drugs 54 antitumoral 54 Cytolin R 54 Pertuzumab 54 neuro inflammatory 54 antigen sparing 54 PI3K delta 54 PNP inhibitor 54 diagnostic biomarker 54 targeted biologic therapies 54 RECAF TM 54 small molecule agonists 54 BGC# 54 Exelixis compounds 54 heterogeneous catalysts 54 recombinant antibodies 54 Xencor XmAb 54 Activity Assay 54 microtubule inhibitor 54 oncolytic viruses 54 lentiviral vectors 54 multiphoton microscopy 54 deacetylase inhibitors 54 photodynamic 54 protein kinase inhibitor 54 targeted radiotherapeutic 54 transdermal gel 54 Guanilib 54 synthetic peptides 54 targeted antifolate 54 Valdoxan 54 act synergistically 54 Corus CAD 54 ReCyte 54 cytoprotective 54 DsiRNA 54 HDAC enzymes 54 signal transduction inhibitor 54 drug eluting stent DES 54 Transdel TM 54 interventional therapies 54 entacapone 54 antithrombotics 54 Cyclosert 54 biomodulator 54 Src inhibitors 54 Poly ICR 54 MolecularBreeding 54 EML4 ALK 54 predictive biomarkers 54 Aquinox 54 INT# [002] 54 antidiabetic drugs 54 biomarker assay 54 biochemical profiling 54 glycosylation profile 54 5 hydroxymethylcytosine 54 nanoelectronic devices 54 tyrosine kinase inhibitor TKI 54 Shark cartilage 54 pharmacological chaperone 54 fusion inhibitor 54 Sugammadex 54 retinoid 54 bioimaging 54 tyrosine kinase inhibitors 54 TLR9 agonists 54 anti angiogenic agents 54 Factor Xa inhibitors 54 Hydroxyapatite HAp 54 QTinno TM 54 cytotoxic agents 54 ALN TTR# 54 CFTR inhibitors 54 kinase inhibitor 54 multimodality imaging 54 selective inhibitor 54 Sopherion 54 pharmacological therapies 54 AvalonRx R 54 lipidoid 54 AMPK activators 54 DSSCs 54 synthetic genomics 54 enzyme inhibitor 54 potent cytotoxic 54 LentiVector technology 54 conjugate vaccines 54 Amplimexon 54 mda 7 54 adrenal steroid hormones 54 patented NanoStat TM 54 integrase inhibitor 54 cognitive enhancer 54 dexpramipexole 54 nanoviricide 54 immunoregulation 54 mitochondrial inhibitor 54 anticancer treatments 54 antiviral therapies 54 sphingolipid 54 kinase profiling 54 LSI #P 54 PI3K inhibitor 54 Nanobodies ® 54 HemoTech TM 54 Hsp# inhibitor 54 CMOx TM 54 idarubicin 54 fibrotic disease 54 BRAF inhibitors 54 TLR8 54 protein tyrosine phosphatases 54 Qdot 54 oxidative stress inducer 54 stimulate insulin secretion 54 #F FDG PET 54 FVIIa 54 protein homeostasis 54 JAK2 inhibitor 54 tubulin inhibitors 54 Inhaled nitric oxide 54 SNP Array #.# 54 cellular immunotherapy 54 conductive plastics 54 curative therapies 54 electro optic polymers 54 integrase inhibitors 54 accumulate preferentially 54 Bellicum Pharmaceuticals Inc. 54 novel immunomodulatory 54 retroviral vectors 54 TRIOLEX TM HE# 54 IAP inhibitors 54 DXL# 54 oncolytic virus 54 OHR/AVR# 54 small molecule activator 54 glycosylated 54 photocatalysts 54 epigenetic therapies 54 Curaxin CBLC# 54 CXCR4 receptor 54 TNF alpha inhibitor 53 anti CD# antibodies 53 triple quadrupole mass spectrometer 53 nucleoside analogues 53 myelofibrosis polycythemia vera 53 cationic lipids 53 theranostic 53 pro angiogenic 53 anti angiogenic therapies 53 echinocandin 53 pharmacological approaches 53 CCR3 53 busulfan 53 blood clot dissolver 53 ACTCellerate 53 coronary stenting 53 LNPs 53 cancer therapeutics 53 therapies 53 potent inhibitors 53 Lauriad 53 Tr DNA 53 oral prodrug 53 small molecule inhibitor 53 agonism 53 biocatalysts 53 pharmacologic intervention 53 prostone 53 systemic immunosuppressive drugs 53 immune modulating 53 PbC battery 53 cytotoxic chemotherapy 53 DirectSelect TM 53 telomerase inhibitors 53 VAPRISOL 53 humanized monoclonal 53 Lisofylline 53 commercializable 53 PEGylated 53 microbubble 53 dendritic cell vaccines 53 kidney urologic 53 Sym# 53 bispecific antibody 53 JAK3 53 therapeutic modalities 53 Chk1 inhibitors 53 biologic therapies 53 immunotherapeutic 53 liposomal formulations 53 Panzem R NCD 53 GIPET 53 cytotoxics 53 humanized antibodies 53 mitotic kinesins 53 novel antiviral therapeutics 53 clinically differentiated 53 Talabostat 53 GPCR targets 53 regorafenib 53 olfactory perception 53 nanocarrier 53 reuptake inhibitors 53 AV HALT 53 DiLA2 53 NuMimetic TM 53 JAK1 53 diagnostic modality 53 vidofludimus 53 riociguat 53 epitaxial structures 53 Calibrant 53 TLR9 agonist 53 HIV integrase inhibitors 53 proteins peptides 53 BACcel 53 pharmacologic 53 CCR1 53 anti angiogenic 53 anti infective therapies 53 bispecific antibodies 53 microRNA therapeutics 53 small molecule 53 stem cell therapeutics 53 eIF 4E 53 obatoclax 53 histone deacetylase inhibitor 53 eTag assays 53 vivo potency 53 cartilage regeneration 53 Inhaled corticosteroids 53 Neowater TM 53 molecularly targeted therapies 53 JAK#/JAK# 53 FPGA Supercomputing 53 fatty acid biosynthesis 53 ErbB1 53 TRC# 53 transgenic mouse models 53 Célle 53 systemic RNAi 53 ospemifene 53 ANTISENILIN ® 53 ViaDerm 53 Tamibarotene 53 MEK ERK 53 anemias 53 Starpharma dendrimer 53 immunomodulatory 53 oncology therapeutics 53 uricase 53 bioactive lipids 53 enhance ApoA 53 peptide inhibitors 53 Fibroblast Growth Factor Receptor 53 radionuclide therapy 53 spintronic 53 investigational therapies 53 Inhaled AAT 53 progressive neurodegenerative disorder 53 atomically precise manufacturing 53 genetic biomarkers 53 validating biomarkers 53 Tekmira lipid nanoparticle 53 siRNA mediated 53 DepoFoam 53 LHRH agonists 53 selective kinase inhibitor 53 IFS 2C 53 CD# antibody [001] 53 receptor modulators 53 GelSite R polymer 53 Panzem 53 angiogenesis inhibitor 53 BRAF kinase 53 antineoplastic agents 53 SIRT1 activators 53 convenient dosing regimens 53 sublingual formulation 53 VIAdel TM technology 53 pharmacologic treatments 53 bexarotene 53 ESBA# 53 PRT# 53 Ceragenin 53 visilizumab 53 TNFa 53 HyACT 53 pharmacotherapies 53 QTRAP 53 immunological diseases 53 presymptomatic 53 RLY# 53 EGFr 53 KinomeScan 53 TRIOLEX HE# 53 TAFA# 53 imatinib resistance 53 GMX# 53 ClearPath TM 53 GeneICE 53 immunomodulatory therapy 53 MaxCyte STX 53 CEQ# 53 Tumorgraft 53 ARRY # 53 A3 adenosine receptor 53 mertansine 53 biocatalytic processes 53 Neuradiab 53 NexACT 53 Cerashield 53 thrombolytic agents 53 PEGylation technology 53 epigenetic enzymes 52 Debio 52 antibiotic anti infective 52 #beta HSD 1 52 IMA# 52 LDL cholesterol lowering 52 Gefitinib 52 undruggable targets 52 platelet inhibitor 52 synthetic peptide 52 FGFR 52 D#g#tal Dr1ve 52 BioSilicon TM 52 NOX A# 52 nucleoside analogs 52 orphan GPCRs 52 immunomodulator 52 Onconase 52 Dicer Substrate Technology 52 Pathway Inhibitor 52 ISF# 52 U1 Adaptor 52 ChronVac C R 52 echinocandins 52 quantitative proteomics 52 Silodosin 52 antiproliferative effects 52 oncolytic 52 Contramid R 52 pyrimidines 52 ddRNAi 52 muscular dystrophies 52 thapsigargin 52 biomarker assays 52 tetrapod quantum dots 52 RECOTHROM R 52 AChE inhibitors 52 proven proprietary AcuForm 52 bioseparation 52 aptamers 52 noninfectious uveitis 52 Dasatinib 52 Sapacitabine 52 Cylene 52 PD2i ® algorithm 52 CD# monoclonal antibody 52 neurogenic 52 Aviptadil 52 optogenetic 52 liposomal 52 Tarvacin 52 immunotoxin 52 nanocomposite materials 52 Captisol 52 therapeutic radiopharmaceuticals 52 mass spectrometry instrumentation 52 lymphoid tumors 52 PET molecular imaging 52 p# inhibitors 52 anti restenotic 52 hES cells 52 MMP inhibitors 52 humanized antibody 52 ZFN technology 52 regenerative medicine therapies 52 Vidaza azacitidine 52 UsiRNAs 52 Aethlon ADAPT ™ 52 therapeutic regimens 52 histone deacetylases HDACs 52 hypoxic tumors 52 chemopreventive agent 52 5 HT2C receptor 52 JAK inhibitor 52 tyrosine kinase inhibitor 52 sd rxRNAs 52 noninvasive prenatal tests 52 depsipeptide 52 Annamycin 52 mechanistic insights 52 intranasal delivery 52 microdroplet based 52 biocatalytic 52 prophylactic vaccine 52 TriGrid ™ 52 standard chemotherapy regimens 52 situ gelling 52 BioSilicon 52 antisense compounds 52 REG1 52 GPx 52 refractory angina 52 erlotinib Tarceva 52 preclinical compounds 52 AAIsafeR 52 TOCOSOL Camptothecin 52 antiviral therapeutics 52 secretory pathway 52 EndoTAG TM 52 pertuzumab 52 PI3K/Akt pathway inhibitor 52 ErbB3 52 CINQUIL 52 gemcitabine Gemzar 52 Chemokine Receptor 52 norepinephrine reuptake inhibition 52 MAXY G# 52 lysosomal enzyme 52 sd rxRNA compounds 52 MediVas 52 N glycan 52 GRN# 52 targeting CD# 52 carbohydrate compounds 52 telomerase activation 52 Gleevec resistant 52 biocompatible polymers 52 proprietary chromatographic purification 52 nucleotide analogs 52 Nucleic acids 52 boron chemistry 52 Therapeutic antibodies 52 Interferon alpha 52 JAK2 inhibitors 52 neuronal nicotinic receptors NNRs 52 OvaRex R 52 Anticalin 52 engineered proteases 52 hematopoietic malignancies 52 NanoCrystal Technology 52 P2V TM 52 NS4B 52 PSMA ADC 52 MYDICAR ® 52 MEK inhibitor 52 antimetabolite 52 thymidylate synthase TS 52 resorbable biomaterials 52 investigational humanized monoclonal antibody 52 VEGF receptor 52 Mitoxantrone 52 biotherapies 52 LNA TM 52 levodopa carbidopa 52 anti thrombotic 52 siRNA sequences 52 lupus nephritis 52 PyraDerm TM 52 WS CRDS 52 supercritical fluids 52 accurate quantitation 52 HQK 52 radiotracers 52 Halozyme Ultrafast Insulin 52 GlycoPEGylation TM technologies 52 Crystalens AO 52 Myotech CSS 52 nanopore sequencing 52 metabolomic profiles 52 circuitries 52 mTOR inhibition 52 protein quantitation 52 anticancer drugs 52 Ii Key 52 oral anticancer 52 mAbs 52 RGD peptide 52 ZFPs 52 cytotoxic compounds 52 thermostable 52 antibody therapeutics 52 Phylomer ® 52 teriflunomide 52 adenosine receptor 52 proteomic biomarkers 52 NRAM TM 52 Alequel TM 52 epothilones 52 aggregated Abeta 52 somatostatin analogue 52 Referenced EEG 52 HepDirect technology 52 biomolecular interactions 52 DETERx ™ 52 pharmacological 52 Rasagiline 52 ThermaVolt 52 anticancer compound 52 VA# [002] 52 selective serotonin 2C receptor 52 nitride semiconductor 52 commercialize microRNA 52 ANG# 52 Aeolus Pharmaceuticals 52 potentiostat 52 macrocycles 52 Selective Electrochemical Tumor Ablation 52 Oral Spray 52 WELD PLANNER 52 ALN TTR 52 anti miRs 52 mRNA antagonists 52 kinase assay 52 DiLA2 Platform 52 endogenous ligands 52 NeoLipid TM 52 Combo Stent 52 Carigent 52 siRNA compounds 52 OXi# 52 multidose dry 52 Theranostics 52 nanoparticulate 52 TÎ ² 4 52 doxorubicin HCl 52 affinity ligands 52 phage display libraries 52 Mass spectrometry 52 Aricent ISS 52 RAS MAPK pathway 52 c MET 51 glial tumors 51 tiapamil 51 near infrared spectroscopic 51 humanized monoclonal antibodies 51 bioartificial liver 51 NOD mouse 51 Hemospan 51 FE DMFC 51 ADME properties 51 DepoVax 51 electro optic polymer 51 OncoGel 51 oral ghrelin agonist 51 ulimorelin 51 allosteric modulator 51 Salk scientists 51 Imatinib 51 antibody fragment 51 immune modulatory 51 fusion proteins 51 IAP inhibitor 51 microwell plate 51 Integrase inhibitors 51 lentiviral 51 multiplex immunoassays 51 ProLindac TM 51 OXIGON TM 51 OncoVEX GM CSF 51 neoplastic diseases 51 VersaFoam 51 abzymes 51 anti infective treatments 51 oral proteasome inhibitor 51 indibulin 51 regenerative therapy 51 biologic therapy 51 aptamer therapeutics 51 HuCAL 51 NPC 1C 51 HDACs 51 NIC5 51 Molecular imaging 51 Tocomin ® ™ 51 LY# [003] 51 siRNA delivery 51 Dyax phage display 51 AtuRNAi 51 efficacious therapies 51 receptor monoclonal antibody 51 ADME Tox 51 romazarit 51 liposomal delivery 51 POTELLIGENT ® 51 FLT3 51 antiarrhythmic 51 antagomirs 51 proprietary bioresorbable polymer 51 Sphingomab 51 CRTH2 51 spintronic devices 51 Amrubicin 51 neuroprotectant 51 CardioPET 51 cilengitide 51 cediranib 51 chemotherapeutic agents 51 Taxanes 51 Stapled Peptides 51 monoclonal antibody MAb 51 CTLA4 Ig 51 antithrombotic therapy 51 LHRH agonist 51 muscle contractility 51 cardiotoxic 51 abiotic stress tolerance 51 LCQ Fleet 51 epigenomics 51 isoprenoid 51 oral anticoagulant 51 anticancer therapy 51 Receptos 51 chemotherapeutic 51 CDK inhibitor 51 multi kinase inhibitor 51 Neovasc Reducer TM 51 stent coating 51 histone deacetylase 51 CellPort Technologies 51 Capsulution 51 Pentraxin 2 51 Accelerated Seldinger Technique 51 neurotrophic 51 clot retrieval 51 synergistic combinations 51 Anticalin R 51 proteomic analysis 51 HDAC inhibitor 51 nCounter Analysis System 51 patented NanoStat ™ 51 Adaptive DPSK 51 chemotherapeutic regimens 51 DNA methyltransferases 51 combinatorial libraries 51 splice variant 51 BAY #-# 51 Adnectins 51 RNAi therapeutic targeting 51 vivo fluorescence imaging 51 topiramate Topamax 51 oral talactoferrin 51 Transfluor 51 CMOS photonics