Related by context. All words. (Click for frequent words.) 65 Survival 58 Kloski noted 58 furthers procreation essential 54 survive 53 fittest Bucher 52 surviving 50 survivals 49 survivability 48 survivial 48 Median progression 47 Free Survival PFS 46 progression TTP 46 mortality 45 locoregional control 45 Spokeswoman Amy Cianciaruso 44 Sovereign Deed LLC 43 Bystander CPR 43 Helicopters whirred overhead 42 locoregional disease 42 Disorienting episodes added 42 Petty Officer Crystal Kneen 42 forequarter amputation 42 Portable defibrillators 42 VIDAZA azacitidine 41 Kaplan Meier 41 VcMP 41 biochemical recurrence 41 bacterial bloodstream infections 41 prognosis 41 survial 41 bears Servheen 40 stage IIIB IV 40 KellyAnn Bonnell whose 40 Kaplan Meier method 40 dying 40 Median survival 40 recurrent GBM patients 40 horror experienceA student 40 recurrent Hodgkin 40 free survival PFS 40 Chermaine Lee 40 irradiated mice 39 inexpressible joy 39 biochemical relapse 39 Michael Fricklas Viacom 39 neoadjuvant therapy 39 disease progression TTP 39 Max Newnham 39 resected pancreatic cancer 39 skin sparing mastectomies 39 cytoreduction 39 Rectal cancer 39 allogeneic SCT 39 ALSFRS R 39 Kaplan Meier analysis 39 survived 39 viability 39 CR nPR 39 Kattmeyer 38 ovarian function 38 locoregional 38 locoregional recurrence 38 squamous histology 38 Kaplan Meier estimates 38 oceanic ecosystems 38 operable breast cancer 38 myeloablative 38 TUCSON Ariz. Recovering 38 ALND 38 Knivila 38 distant metastasis 38 longevity 38 Kaplan Meier estimate 38 androgen deprivation 38 mildly hypothermic 38 prolongs survival 38 CYP#D# genotype 38 Roma Rosenblat recantation 38 oral Hycamtin 38 habitat poaching 37 5-fluorouracil/leucovorin 37 perioperative morbidity 37 medically inexplicable 37 sustained virologic response 37 immune reconstitution 37 EGFR mutation positive 37 KRAS status 37 Captive breeding 37 curability 37 lethally irradiated 37 courtesies seamanship skills 37 Halaven 37 Garcia Manero 37 Lung transplantation 37 virologic response 37 shortened lifespan 37 Tassie devil 37 plus prednisone 37 distant metastases 37 BEXXAR Therapeutic Regimen 37 Ora Doris 37 type KRAS 37 engraftment 37 mutant KRAS 37 % CI #.#-#.# [003] 37 pCR 37 Domenick Brouillette 37 surgical debulking 37 undetectable PSA 37 KRAS mutant 37 median survivals 37 limb salvage 36 pancreatic adenocarcinoma 36 tumor recurrence 36 avoiding relegation 36 Said Hirsh 36 nonmetastatic 36 Bcl xL 36 durable remissions 36 fecundity 36 unresectable stage 36 lung metastasis 36 FOLFOX 36 preoperative chemotherapy 36 virological suppression 36 liver metastasis 36 untalented contestants 36 tumor resection 36 sickest colon cancer 36 Businesses battening 36 resilience 36 oral clodronate 36 IV malignant melanoma 36 tumor shrinkage 36 Rio Grande silvery minnow 36 Metastatic colorectal cancer 36 recurrence 36 RBC transfusion 36 Fiddler crabs 36 Universal Sanctum 36 stage IIIb IV 36 target lesion revascularization 36 non mutated KRAS 36 autologous transplants 36 hormone receptor status 36 clonogenic 36 KRAS wild 36 reoperation 35 untreated mice 35 automakers KeyBanc 35 K ras gene 35 incurable prostate 35 sustained virological response 35 pT3 35 postoperative mortality 35 extinction 35 cardiomyocyte proliferation 35 surivors 35 Anessa Rahman co 35 cancer mCRC 35 EGFR mutation status 35 FOLFOX4 35 mutated KRAS 35 Prognostic factors 35 Sophisticated treadmills 35 virologic responses 35 FOLFIRI alone 35 aristocratic splendor 35 tumor regression 35 satraplatin Phase 35 randomized multicenter Phase III 35 mCRC patients 35 R0 resection 35 Dr Luckin 35 postoperative chemotherapy 35 neoadjuvant radiation 35 Rasool Bakhsh Rais 35 RBC transfusions 35 islet transplants 35 Clot busting 35 bone metastasis 35 genetic variability 35 bystander CPR 35 evolutionary adaptations 35 colorectal metastases 35 ERCC1 35 Survitec 35 curative resection 35 genetic diversity 35 tiniest preemies 35 debulking surgery 35 antibody mediated 35 alveolar rhabdomyosarcoma 35 postoperative radiotherapy 35 underwent resection 35 progression 35 prognostic factor 35 refractory colorectal cancer 35 neurologic progression 35 urgent revascularization 35 oblimersen 35 Adjuvant therapy 35 arterial thickening 35 leukaemic cells 35 CR CRu 35 Chronic Myeloid Leukaemia 35 radiochemotherapy 35 care regimens CCR 35 survivorship 35 KRAS mutant tumors 35 Adjuvant chemotherapy 35 perpetuation 35 plus dexamethasone 35 survives 35 mutant p# 35 mitoxantrone 35 Rosendo Delgado 35 diffuse intrinsic pontine glioma 35 complete cytogenetic response 34 owl kingdoms 34 CD4 + lymphocytes 34 median PFS 34 standard chemotherapy regimen 34 reintervention 34 custirsen 34 adjuvant cisplatin 34 adjuvant therapies 34 lymph node involvement 34 success 34 pool accidentA little 34 protein Mcl 1 34 HRPC 34 tumor subtype 34 yellow legged frogs 34 hormone refractory 34 posttransplant 34 metastatic castration resistant 34 Muraskas 34 Avastin Tarceva 34 PSADT 34 pig islets 34 disease progression 34 Wound healing 34 kidney allograft 34 randomized Phase 2b 34 adjuvant radiation 34 tumor progression 34 radioiodine therapy 34 acute lymphoblastic 34 anthracycline containing 34 NSCL cancer 34 Richard Pazdur MD 34 Randomized clinical trials 34 fantastical tale 34 Alpine Meadows ski 34 Tom Luchento president 34 tumor progression TTP 34 KRAS mutations 34 Circulating tumor cells 34 VT VF 34 CCyR 34 term nonprogressors 34 IL 7R 34 radical prostatectomy 34 life expectancy 34 HNSCC 34 Wang Ziqi director 34 endangered marsupials 34 leukemic stem cells 34 prostate cancer CRPC 34 stage IIIA 34 siblings girls Ebuka 34 ECD kidneys 34 neurodevelopmental impairment 34 reperfusion 34 Untreated mice 34 pulmonary metastasis 34 sentinel lymph node biopsy 34 curative treatments 34 nephron sparing surgery 34 KRAS mutation status 34 cystectomy 34 oncologic outcomes 34 gemcitabine carboplatin 34 remission CR 34 tesmilifene 34 Unhealthy habits 34 Progression 34 histologic 34 diffuse pontine glioma 34 Reducing maternal mortality 34 kidney transplant recipients 34 transplanted kidneys 34 life 34 immunosuppressive regimens 34 BREAST cancer 34 EUROCARE 34 Caloric restriction 34 Recurrence 33 perioperative complications 33 RECIST criteria 33 hematologic malignancy 33 BRCA carriers 33 bronchopulmonary dysplasia BPD 33 Species extinction 33 hover precariously 33 lymph node dissection 33 Parma wallabies 33 resuscitation 33 node dissection 33 eribulin 33 anoikis 33 stem cell engraftment 33 spawning escapement 33 seemingly insurmountable odds 33 follicular Non Hodgkin 33 ferroportin levels 33 PSA nadir 33 response pCR 33 % CI #.#-#.# [007] 33 Eliezer Zomer Ph.D. 33 rock crystal ewers 33 Yangtze finless porpoise 33 ADVEXIN efficacy 33 tenecteplase 33 antioxidant supplementation 33 gp# vaccine 33 Microbial Ecology Journal 33 leukaemic 33 Autologous stem cell 33 Dr. Hennenfent 33 Secondary endpoints include 33 bioartificial kidney 33 Mortality 33 leukemic bone marrow 33 prognostically 33 nodal metastasis 33 catheter colonization 33 pulmonary dysfunction 33 baseline CD4 + 33 patients undergoing chemotherapy 33 peritoneal carcinomatosis 33 Median PFS 33 substantially improves treatability 33 Improved Progression 33 palliation 33 kangaroo rats 33 CMV disease 33 liver metastases 33 citing Wang Ziqi 33 prematurity birth defects 33 underwent liver transplantation 33 nonischemic cardiomyopathy 33 lung transplantation 33 anti leukemic 33 cabazitaxel 33 A1c levels 33 cintredekin besudotox 33 SEALFIT camp 33 cytogenic 33 cancer recurred 33 breed giant pandas 33 transplantation HCT 33 remission 33 neoadjuvant chemotherapy 33 transplanted organ 33 called Abydosaurus mcintoshi 33 surrogate endpoint 33 Inhaled nitric oxide 33 Immunosuppressive drugs 33 revascularisation 33 chemoradiation 33 spontaneous circulation ROSC 33 cowbird chicks 33 prognostic indicator 33 resensitize 33 T1c 33 Natalie Portman ballet 33 topotecan 33 telomere lengths 33 TYAs 33 chemoradiotherapy 33 small lymphocytic lymphoma 33 hyperglycaemic 33 Kaplan Meier curve 33 relapse 33 islet transplant 33 FOLFIRINOX 33 induced neuropathy 33 seminoma 33 cytoreductive surgery 33 spontaneously regress 33 chemotherapy 33 cyclophosphamide chemotherapy 33 PROSTVAC VF 33 Radical prostatectomy 33 Acute myeloid leukemia 33 advanced individualized immunotherapies 33 neutrophil counts 33 VIDAZA ® 33 ADVEXIN therapy 33 salvation 33 extirpation 33 renal transplantation 33 GVAX 33 virological response 33 normothermia 33 serum clusterin levels 33 radiographic progression 33 homing instincts 33 prostate tumor 33 childhood acute lymphoblastic 33 lymph node metastasis 33 cells multiply uncontrollably 33 HH GLI 33 intensity allogeneic stem 33 prognostic 33 transplanted islets 33 clodronate 33 MCSD implantation 33 gallstone formation 33 low dose cytarabine 33 peritoneal cancer 33 refractory metastatic 33 Keith Bowermaster 33 EGFR TKI 33 ocular melanoma 33 evolutionary adaptation 33 relapsed SCLC 33 prognostic factors 32 metastatic renal cell carcinoma 32 type KRAS tumors 32 physiological adaptations 32 autologous transplantation 32 Palifosfamide delivers 32 regrow limbs 32 acute myelogenous 32 Graft Versus Host 32 RECIST Response Evaluation Criteria 32 lifesaving 32 gemcitabine 32 bronchopulmonary dysplasia 32 non progressors 32 renal carcinoma 32 neurodevelopmental outcome 32 Migrating songbirds 32 residual stenosis 32 Kalantar Zadeh 32 inducing hypothermia 32 Doxil ® 32 TMEM density 32 minimally symptomatic 32 Critically endangered 32 perioperative mortality 32 zibotentan 32 survival instinct 32 BEACOPP 32 metastasis 32 germination 32 triglyceride concentrations 32 imatinib therapy 32 ispinesib administered 32 heavily pretreated 32 immunosuppression 32 mammary tumor formation 32 Female GIs 32 Tadano cradling 32 androgen suppression 32 patency 32 relapsed ovarian cancer 32 multivessel coronary artery 32 calorie restriction diets 32 auto allo 32 maximal lifespan 32 nonsquamous 32 VEGF inhibition 32 angiographic restenosis 32 vernal pool species 32 immunosuppressive regimen 32 cystic fibrosis sufferers 32 daughter Renesmee 32 metastatic renal 32 temsirolimus 32 SIV infection 32 sheer smallness 32 PCA3 scores 32 KRAS mutation 32 neurodevelopmental outcomes 32 CD4 cell 32 irinotecan chemotherapy 32 ciclosporin 32 liver transplantation 32 innate immune defenses 32 metastatic prostate 32 matching marrow donor 32 abiraterone acetate 32 mTOR inhibition 32 evil Pure Ones 32 p = #.# [004] 32 malignant phenotype 32 Gombe chimps 32 phthalate syndrome 32 allogeneic HSCT 32 chemoresistant 32 abiraterone 32 nonmetastatic breast cancer 32 chemotherapy docetaxel 32 survivin expression 32 graft patency 32 malignant neoplasm 32 extrapleural pneumonectomy 32 seed dispersers 32 CPAP adherence 32 gemcitabine chemotherapy 32 Psychosocial interventions 32 Ets2 32 Vitamin D intake 32 lung fibrosis 32 baseline CD4 32 lymphoma 32 Acute myelogenous leukemia 32 cecal intubation 32 donor pancreases 32 clopidogrel therapy 32 Blood transfusions 32 Tassie devils 32 p# Shc 32 fellow strugglers Bolton 32 Irulas 32 HbA1C 32 granulocyte 32 TroVax ® 32 muscular dystrophy cystic fibrosis 32 Proper nutrition 32 thrombotic complications 32 XL# administered orally 32 immunosuppressive medication 32 uninterrupted chest compressions 32 bleak prognosis 32 mutated K ras 32 neurocognitive function 32 HSCT 32 completely resected 32 precancerous colon growths 32 ovulatory cycles 32 humoral immunity 32 CD4 + cell 32 platelet transfusion 32 ulcer healing 32 NNRTI resistance 32 burdensome prolongation 32 Non Hodgkins Lymphoma 32 nestin expression 32 chemosensitivity 32 GISTs 32 antithrombotic therapy 32 noncarriers 32 colorectal cancer liver metastases 32 BMPR2 32 lifesaving jolts 32 circulating lymphocytes 32 surgical resection 32 lymphocyte count 32 prospectively stratified 32 tumor histology 32 adjuvant chemotherapy 32 angiogenesis inhibition 32 FLT3 ITD 32 detecting precancerous 32 KRAS gene 32 Hormone Refractory Prostate Cancer 32 enzymatic modification 32 called ammart 32 cardiac allograft vasculopathy 32 mammary tumor 32 rituximab refractory 32 estramustine 32 shrink cancerous tumors 32 WNV encephalitis 32 cardiac dysfunction 32 chemo radiotherapy 32 faulty BRCA2 gene 32 noncardiovascular mortality 32 preeclamptic 32 recurrent VTE 32 ashy storm petrels 32 intravenous CK # 32 infarct size 32 extracapsular extension 32 Stage IIIb 32 androgen ablation 32 pegylated liposomal doxorubicin 32 neoadjuvant 32 Narod 32 CD# upregulation 32 PDE7B 32 liver transplant recipients 32 reproductivity 32 poorer prognosis 32 doxorubicin docetaxel 32 prognostic indicators 32 RECIST 32 antiangiogenic agents 32 evolutionary lineage 32 surive 32 #.#ng/ml 32 Kaklamani 32 imperiled 32 stage IIIb 32 heavily pretreated patients 32 chick hatches 32 recurrent metastatic 32 metastatic kidney 32 glomerular filtration 32 Genetic variation 32 inhaled tobramycin 32 coronary revascularization 32 visceral metastases 32 motility 32 IDH2 32 chronic HBV 32 clinicopathological features 32 antitumor effect 32 TRAIL induced apoptosis 32 genetically identical 32 carnivorous predators 32 localized prostate 32 iniparib BSI 32 nephron sparing 32 ras oncogene 32 hENT1 32 Cyalume chemical 32 immunosuppression therapy 31 synovial cell 31 Extinction 31 severe neutropenia 31 systolic function 31 chimpanzees bonobos 31 immunosuppressant medications 31 Malaria parasite 31 adjuvant hormonal therapy 31 genomic imprinting 31 Skydive survivor 31 glufosfamide 31 clinically localized prostate 31 KRAS 31 tiny invertebrates 31 chronic myeloid 31 whales dolphins porpoises 31 Kim Ho keun 31 rhabdoid 31 Leukemia lymphoma 31 vasectomy reversal 31 preservation 31 sabertooth cats 31 Mariana crows 31 solenodon 31 neurologic outcomes 31 preparedness 31 recanalization 31 survivors 31 ipilimumab 31 perioperatively 31 viral titers 31 clinicopathological 31 cytogenetic response 31 breast conserving lumpectomy 31 avian predators 31 Stage IIB 31 artery reclogging 31 hormonally responsive 31 myocardial viability 31 transplanted marrow 31 axillary dissection 31 pancreatic islet cell 31 colo rectal cancer 31 relapsed AML 31 EGFR mutant 31 circulating endothelial 31 moist meadows 31 spontaneous regression 31 bortezomib 31 Asiatic cheetahs 31 male silverbacks 31 radical retropubic prostatectomy 31 Kaplan Meier curves 31 Kate Sofia Vassilieva 31 antithymocyte globulin 31 telomere length 31 Homo sapiens evolved 31 ± SEM 31 life nibbling decomposed 31 BRCA mutation carriers 31 baseline LDH 31 freshwater invertebrates 31 mammary tumors 31 CMV reactivation 31 pemetrexed 31 livelihood 31 acute GVHD 31 dwelling mammal 31 preoperative PSA 31 parkinsonian symptoms 31 localized renal 31 telomerase activity 31 metastatic gastric 31 Scooptown 31 symptomatic intracerebral hemorrhage 31 P = .# 31 GvHD 31 prognostic marker 31 MIF gene 31 Partial Responses 31 wellbeing 31 lymphoid cancers 31 EGFR expressing mCRC 31 fibrinolysis 31 hematopoietic cell 31 neoadjuvant chemoradiotherapy 31 leukocyte count 31 ringed seal pups 31 induce remission 31 relapsed GBM 31 renal allograft 31 standard chemotherapy regimens 31 gefitinib 31 haematopoietic 31 cisplatin chemotherapy 31 erlotinib 31 nadroparin 31 twin Candice Hermeler 31 Folfox 31 zoledronic acid 31 seroprotection 31 intra arterial chemotherapy 31 indolent lymphomas 31 summum bonum 31 etoposide 31 Gleevac 31 anti inflammatory cytokine 31 hyperoxia 31 carboplatin 31 relapsed ALL 31 Hh pathway 31 moderate immunologic 31 GBV C 31 Wearing seatbelt 31 Locust Horde nightmarish 31 stay afloat 31 myeloma 31 Sonoran pronghorn 31 p# biomarkers 31 incidental bycatch 31 seabird populations 31 dopaminergic neuron 31 VIDAZA 31 AJCC 31 asexual organisms 31 K ras mutation 31 milatuzumab 31 Rocky Thyme 31 Paraplatin ® carboplatin 31 AZA zoos 31 stem cell transplant 31 mismatched bone marrow 31 cisplatin gemcitabine 31 Oral Cavity Soft Palate 31 metabolize sugar 31 dinosaur physiology 31 BR.# study 31 Whooping crane 31 Dr. Paul Fassbach 31 survivalism 31 nodal metastases 31 SURVIVAL 31 estrogen receptor negative 31 clinically evaluable patients 31 sea turtle populations 31 thymic carcinoma 31 kidney transplantation 31 chemotherapeutic regimens 31 rescuing 31 perinatal asphyxia 31 prognostic significance 31 multiple myeloma MM 31 Sumatran orang utan 31 polyp recurrence 31 transgene expression 31 Liver fibrosis 31 PFS 31 differentiating squamous 31 evaluable 31 sustenance 31 NF κB activation 31 dietary regimens 31 Ancrenaz 31 preoperative staging 31 transplanted livers 31 aneuploid 31 pulmonary function 31 anti angiogenic agents 31 Leydig cell 31 pelvic lymphadenectomy 31 cisplatin resistant 31 Xyotax 31 recurrent myocardial infarction 31 refractory ALCL 31 metastatic lung cancer 31 Babec 31 cancerdefine 31 Platinol ® cisplatin 31 conceiving naturally 31 pancreatic resection 31 histological subtype 31 vandetanib #mg 31 imatinib 31 graft dysfunction 31 http:/media#.washingtonpost.com/wp-dyn/content/phSamantha Cassetty 31 T1a 31 overexploit 31 adenoma recurrence 31 axitinib 31 ependymoma 31 Selwin Hart delegate 31 chemoresistance 31 livelihoods 31 bowel resection 31 continuous chest compressions 31 Secondary endpoints included 31 ixabepilone 31 pulmonary artery banding 31 morbidity mortality 31 yachting vacation 31 oncological outcomes 31 following antiestrogen therapy 31 heel lance 31 verified Volkow 31 mRCC 31 cisplatin 31 demonstrated antitumor activity 31 Rescuing 31 QRS interval 31 Chronic lymphocytic leukemia CLL 31 Colleen Manassa assistant 31 brood parasitism 31 lifelong immune suppressing 31 Vectibix monotherapy 31 recurrent wheezing 31 5FU 31 interferon ribavirin 31 Pribilofs 31 synthase TS 31 concurrent chemoradiation 31 FOLFIRI 31 confirmed CCyR 31 gastric atrophy 31 dopamine neuron 31 intraperitoneal therapy 31 adjuvant therapy 31 Lvov Poland 31 myelogenous leukemia 31 cardiopulmonary resuscitation 31 CD4s 31 lung scarring 31 Ozark hellbender 31 TNFerade 31 Caribbean monk seals 31 percutaneous biopsy 31 self sufficiency 31 LVEF 31 Colorectal cancer incidence 31 tumor regressions 31 rats stoats 31 Vectibix 31 noninfected 31 stratifying 31 Jhdm2a 31 preterm newborns 31 SOCS2 31 malignant brain 31 Matrix ARV 31 carotid plaques 31 Implantable cardioverter defibrillators ICDs 31 bevacizumab Avastin Genentech 31 lifespan 31 outcomes 31 rFVIII 31 melanocyte 31 prostate cancer CaP 31 p = #.# [002] 31 irrigation shutoffs 31 chemotherapies 31 ER CHOP 31 natterjack toad 31 BioShock toolset 31 decitabine 31 taxotere 31 poult survival 31 modified RECIST criteria 31 seropositivity 31 chronic HCV genotype 31 invasiveness 31 revascularization 31 Mdm2 31 postmenopausal breast cancer 31 cells/mm3 31 rapid virological response 31 Oesophageal cancer 31 Wilms tumors 31 pulmonary exacerbations 31 phenotypic expression 31 embryo implantation 31 breat cancer 31 extra centrosomes 31 prognostic variables 31 non Hodgkin Lymphoma 31 AML acute myeloid 31 pulmonary exacerbation 31 viral reactivation 31 vaccine Oncophage 31 paclitaxel poliglumex 31 phenotypic characteristics 31 Quino checkerspot butterfly 31 breast cancer recurrence 31 Randomized trials 31 refractory acute myeloid 31 paclitaxel cisplatin 31 marsupial carnivore 31 waterfowl populations 31 Mathematical modeling 31 Major Adverse Cardiac 31 telomere shortening 31 HIV tropism 31 exogenous insulin 30 EGFR inhibitors 30 ungulate species 30 recurrent glioblastoma 30 sero positive 30 hemodialysis patients 30 suppress viral replication 30 humanlike creatures 30 MACCE 30 Liver transplant 30 Eleanor Bimla Schwarz 30 carboplatin chemotherapy 30 swim Dorrestijn 30 EGFR mutation 30 Colorectal cancer screening 30 unless Widrlechner 30 Lorianne Masuoka MD 30 nesting females 30 EGFR expression 30 attain statistical significance 30 dacarbazine chemotherapy 30 Waldenstrom macroglobulinemia 30 binary restenosis 30 spontaneous preterm delivery 30 relapsed follicular 30 Exclusive breastfeeding 30 β cell 30 placental malaria 30 Stomach stapling 30 penguin colonies 30 fight Tutka 30 wife Delyse 30 chronic periodontitis 30 epirubicin cyclophosphamide 30 musician Wladyslaw Szpilman 30 methotrexate monotherapy 30 CRp 30 valley elderberry longhorn beetle 30 paclitaxel carboplatin 30 intra abdominal abscess 30 oncoplastic 30 castrate resistant 30 nocturnal hypoglycaemia 30 hepatic fibrosis 30 lung function 30 MELD scores 30 dozen concrete fishways 30 invasive fungal 30 persistency mortality 30 ungulate populations 30 myocardial function 30 lowering blood glucose 30 cranial irradiation 30 Shark cartilage 30 IV NSCLC 30 Horseshoe crabs 30 mg kg dose 30 hematopoetic stem cells 30 pelvic radiotherapy 30 neoadjuvant treatment 30 Floreana mockingbird 30 de ath 30 virologic failure 30 previously untreated follicular 30 asymptomatic PAD 30 achieving sustained virologic