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(Click for frequent words.) 65 transcriptional activation 64 Src kinase 64 MAP kinase 64 BCL2 64 Rho GTPases 63 tropomyosin 63 PIP2 63 phosphoinositide 63 Hfq 63 Smad3 63 deacetylation 62 tumor suppressor protein 62 cytokine receptors 62 serine threonine kinase 62 ERK signaling 62 PAK1 62 ß catenin 62 NFkB 62 Hedgehog signaling 62 Arp2 3 61 PAR1 61 PGC1 61 SGK1 61 vacuolar 61 mitogen activated protein kinase 61 Transcriptional 61 mitotic checkpoint 61 Rap1 61 uPAR 61 actin cytoskeleton 61 SUMOylation 61 prostaglandin synthesis 61 NF kappaB 61 anaphase promoting complex 61 overactivation 61 downstream effectors 61 antisense molecules 61 molecular signaling pathway 61 Foxp3 60 FGFs 60 Mdm2 60 JAK STAT 60 E3 ligase 60 repressor 60 intracellular signaling 60 β catenin 60 transactivation 60 neurite outgrowth 60 PGC 1α 60 kinase gene 60 H#K# [001] 60 Phosphorylation 60 transcriptional repressor 60 chromatin structure 60 melanocyte 60 β1 60 kinase pathway 60 androgen receptor AR 60 Wnts 60 Cre recombinase 60 FOXO3a 60 histone deacetylases 60 NKX#.# 60 receptor tyrosine kinase 60 helicase 59 effector cells 59 tyrosine phosphorylation 59 epigenetically 59 SOCS3 59 ryanodine receptor 59 Cdc# 59 MT1 MMP 59 proapoptotic 59 misregulation 59 caspases 59 Myostatin 59 peroxisome 59 pRb 59 caveolin 1 59 NFAT 59 autocrine 59 cell motility 59 Clusterin 59 phosphorylates 59 SCD1 59 JAK2 enzyme 59 tumor suppressor PTEN 59 tumor suppressor proteins 59 MEF2A 59 cytokine signaling 59 ubiquitination 59 lysine residues 59 MAPK pathway 59 axon guidance 59 protein phosphatase 59 4E BP1 59 subcellular localization 59 C EBP alpha 59 MAP kinase pathway 59 proteostasis 59 ubiquitylation 59 metalloproteinase 59 tumor suppressor p# 59 Rab5 59 proteolysis 59 Upregulation 59 CDK5 59 beta1 integrin 59 Notch receptor 59 myofibroblasts 59 evolutionarily conserved 59 GTPases 59 cyclic peptide 59 isoenzymes 59 ATPase 59 Runx2 59 PPARγ 59 sRNA 59 receptor gamma 59 protein kinase C 59 cytoplasmic domain 59 sphingolipid 59 MMP2 59 kinase domain 59 upregulates 59 stellate cells 59 GTPase 59 LXRs 59 E#F# 59 GABAA receptor 59 oligomerization 59 beta adrenergic receptors 59 cyclins 59 Flt3 59 homolog 58 proto oncogene 58 osteoclast formation 58 F actin 58 JNK1 58 transcription factors 58 E3 ubiquitin ligase 58 LIS1 58 oncoprotein 58 Oncogenic 58 apoptosis pathways 58 micro RNAs 58 phosphatases 58 catenin 58 AMPA receptor 58 intracellular proteins 58 Nedd4 58 metabolic enzymes 58 gastric carcinomas 58 E cadherin expression 58 cAMP signaling 58 Pdx1 58 paxillin 58 NF kappaB activation 58 forkhead 58 TGF beta1 58 protein tyrosine kinases 58 BMP signaling 58 Wnt proteins 58 epithelial mesenchymal transition 58 casein kinase 58 tyrosine kinase receptors 58 Wnt signaling pathway 58 mediated inhibition 58 KLF4 58 IRE1 58 TOR pathway 58 Wnt pathway 58 COL#A# 58 HDAC3 58 FGF signaling 58 HSF1 58 P cadherin 58 glucocorticoid receptor GR 58 HIF 1a 58 Rho kinase 58 postsynaptic 58 druggable target 58 HIF 1α 58 TGF b 58 p#Kip# 58 alpha subunit 58 tumorigenicity 58 Androgen receptor 58 MAPK 58 Htt 58 fibrogenesis 58 regulates gene expression 58 LRP5 58 beta subunit 58 glucokinase 58 PI3K signaling 58 Wnt signaling 58 ERK1 2 58 Notch signaling 58 activin 58 RNA polymerase II 58 Vpr 58 BCL6 58 EGF receptor 58 cholesterol homeostasis 58 prophase 58 eicosanoid 58 PKC isoforms 58 apoptotic cell 58 apoE 58 Smad proteins 58 chromatin modifications 58 chemokine 58 downregulate 58 epithelial stem cells 58 muscarinic receptors 58 prodynorphin 58 cytosolic 57 multinucleated 57 TrkB 57 protein p# 57 N Myc 57 glutamate signaling 57 c myb 57 cypin 57 GLI1 57 virulence genes 57 Th2 57 FKBP# 57 intronic 57 BRAF protein 57 inducible 57 Sox9 57 histone modification 57 TGF ß 57 RNA polymerases 57 protein kinase 57 VE cadherin 57 Polo kinase 57 TGF beta pathway 57 HepG2 cells 57 GABAergic 57 functional polymorphism 57 Neuropeptide Y 57 NEIL1 57 Runx1 57 EGFR protein 57 morphogenesis 57 EBNA1 57 signaling pathways 57 STAT1 57 vasopressin receptor 57 cystic fibrosis transmembrane conductance 57 histone methylation 57 GLUT4 57 transcriptionally 57 USP# 57 fascin 57 proliferative disorders 57 Ets2 57 BMP4 57 cytochrome P#s 57 CaM 57 beta globin gene 57 constitutively expressed 57 aldose reductase 57 CEACAM1 57 APOBEC3G 57 PC# cells 57 SMAD4 57 PIP3 57 neuronal differentiation 57 opioid peptides 57 KLF# 57 protein tyrosine phosphatases 57 secretory pathway 57 Protein Kinase C 57 miR# 57 immunoregulatory 57 acetylcholine receptor 57 Akt3 57 synapse formation 57 gene p# 57 ligand binding domain 57 nucleoli 57 tumor suppressive 57 constitutively 57 MyoD 57 coactivators 57 orexin receptors 57 mTORC1 57 Dictyostelium 57 pleiotropic 57 mTOR signaling 57 potent inducer 57 branching morphogenesis 57 adenylate cyclase 57 SREBP 57 mutated EGFR 57 biogenesis 57 morphogen 57 actin binding 57 nucleolar 57 overexpressing 57 aminopeptidase 57 oncogenic 57 cyclic nucleotide 57 CXCL# 57 chromosome condensation 57 1beta 57 protein encoded 57 transcriptional regulators 57 lipid synthesis 57 genotoxic stress 57 p# MAPK 57 Src 57 neuromuscular junction 57 NF κB activation 57 HDAC2 57 epithelial mesenchymal 57 BCL#A 57 NOTCH1 57 cyclase 56 Pten 56 cotransporter 56 AhR 56 RhoA 56 Histone 56 secretory 56 ligases 56 alternatively spliced 56 mitogen activated protein 56 cellular pathways 56 signaling cascades 56 DGAT1 56 polyglutamine diseases 56 circadian genes 56 Sox2 56 BMAL1 56 caveolin 56 calpain 56 PTEN gene 56 XBP1 56 IFNg 56 hydrolase 56 Oct4 Sox2 56 transmembrane protein 56 vimentin 56 phagocyte 56 costimulation 56 effector protein 56 MyD# 56 cathepsins 56 E cadherin 56 monocyte 56 Pax6 56 beta catenin 56 demethylase 56 lymphoid cells 56 TFIIH 56 mutant huntingtin protein 56 cell signaling pathway 56 RCAN1 56 GABAA receptors 56 IL 1β 56 Sonic hedgehog 56 subcellular compartments 56 protein acetylation 56 Six3 56 alpha MSH 56 PU.1 56 IFN γ 56 MC4R gene 56 FOXO 56 adhesion molecule 56 neuropeptides 56 MAP kinases 56 urokinase plasminogen activator 56 Wnt 56 secreted protein 56 glutamate receptor 56 mammary stem cells 56 PPARg 56 methylation patterns 56 PKD1 56 neuronal synapses 56 cadherin 56 ribosomal genes 56 HOTAIR 56 transcriptional coactivator 56 neural crest 56 N cadherin 56 exocytosis 56 macrophage activation 56 matrix metalloproteinases 56 signaling pathway 56 G9a 56 Caspases 56 inflammatory cytokine 56 H#K# methylation 56 DDB1 56 FOXO1 56 steroidogenic 56 Notch1 56 endogenous ligands 56 genes encoding 56 SIRT1 gene 56 tRNA synthetase 56 neuronal pathways 56 effector molecules 56 CaMKII 56 habenula 56 PKC zeta 56 phospholipase A2 56 suppressor genes 56 histone H3 lysine 56 adipogenic 56 tyrosine kinase receptor 56 MMP7 56 ERBB2 56 HIF 1alpha 56 inhibit viral replication 56 guanosine 56 GRP# 56 cyclic AMP cAMP 56 TRPV1 receptors 56 monogenic 56 H#K#me# 56 embryonic tissues 56 gene encodes 56 oxidase 56 LSD1 56 metabolizing enzyme 56 bone morphogenetic proteins BMPs 56 protein tyrosine 56 TIR1 56 P#X# receptor 56 upregulating 56 ouabain 56 retinoic acid receptor 56 FasL 56 Skp2 56 pre mRNA splicing 56 mRNA decay 56 agouti gene 56 phagocytosis 56 Wnt1 56 TrkA 56 c Myc 56 N myc 56 membrane proximal 56 palmitoylation 56 antigenic epitopes 56 phosphorylated 56 Sonic Hedgehog 56 actin dynamics 56 chaperone protein 56 innate immune responses 56 hypothalamic pituitary 56 oncogenic signaling 56 TGF β 56 ER alpha 56 prostaglandin E2 PGE2 56 Rb#/p# 56 hormone secretion 56 focal adhesions 56 PLA2 56 presynaptic 55 Abl 55 SMN1 55 CCL# 55 TNFR 55 histone modifications 55 receptor subtypes 55 synthases 55 basolateral 55 viral proteins 55 glycolipids 55 MMP9 55 FGFR3 55 lysosomal 55 cyclin D1 55 cofilin 55 encodes protein 55 Myosin II 55 NF κB 55 rRNA 55 CHD5 55 promoter hypermethylation 55 sortilin 55 mitogen activated protein kinases 55 downregulation 55 HuR 55 Aurora kinases 55 Treg cells 55 gene rearrangements 55 mitogenic 55 Id1 55 Cathepsin B 55 thymocyte 55 proteolytic cleavage 55 glycosyltransferase 55 ARNT 55 microRNA miR 55 ADAM# 55 protein CETP 55 CDK2 55 signaling cascade 55 transcriptional regulator 55 leukemic stem cells 55 Sertoli cell 55 embryonal carcinoma 55 epigenetic modifications 55 effector 55 retinoblastoma protein 55 ubiquitin ligases 55 calcineurin 55 homeobox 55 ZNF# 55 SIRT2 55 histone deacetylation 55 caspase activation 55 CYP#E# 55 ChR2 55 Fas ligand 55 noncoding RNAs 55 matrix metalloproteinase 55 coiled coil domain 55 amyloidogenic 55 EF Tu 55 c Myb 55 transcription factor 55 chromatin remodeling 55 MDM2 55 tyrosine kinases 55 microRNAs miRNAs 55 Lyn kinase 55 E1A 55 telomeric DNA 55 cyclic adenosine monophosphate 55 GPR# [002] 55 OCT4 55 enzymatically active 55 tumor suppressor gene 55 At#g# 55 receptor molecule 55 cryptochromes 55 epigenetic mechanisms 55 molecular determinants 55 ribonucleoprotein 55 Drosha 55 melanocortin receptors 55 LDL receptor 55 protein phosphorylation 55 CPEB 55 γ secretase 55 phosphoprotein 55 FUS1 55 #HT#A receptor 55 FoxP3 55 Rac1 55 hnRNP 55 beta arrestin 55 subunit 55 c MYC 55 HOX genes 55 miRNA expression 55 micro RNA 55 signal transduction 55 myopathies 55 glucocorticoid receptors 55 microRNA molecules 55 protein fragment 55 WNK1 55 TGF ß1 55 protein isoforms 55 serotonin uptake 55 TAp# 55 CXCR2 55 thyroid hormone receptor 55 miR #a [002] 55 K ras gene 55 cystic fibrosis transmembrane 55 NF kappa B 55 tyrosine kinase 55 cofactors 55 LKB1 55 CXCR4 55 constitutively active 55 IGFBP2 55 proteolytic 55 Shh signaling 55 basophils 55 T. brucei 55 malignant phenotype 55 P2X 55 mesenchymal cell 55 nicotinic receptor 55 multigenic 55 NR2B 55 glycoproteins 55 non coding RNA 55 bacterial virulence 55 angiotensinogen 55 proteases 55 ARID1A 55 repressor protein 55 enzymatic activity 55 S#P# 55 transmembrane receptor 55 replicase 55 globin gene 55 activated protein kinase 55 Calcineurin 55 metalloprotease 55 budding yeast 55 SREBP 1c 55 extracellular signal 55 CD#b 55 ubiquitin ligase 55 hypoxia inducible transcription 55 cerevisiae 55 podocyte 55 coreceptor 55 induced phosphorylation 55 PI3 kinase 55 constitutive activation 55 TGFBR1 55 cysteine protease 55 DARPP 55 estrogen receptor alpha 55 hematopoietic progenitors 55 inhibitory receptors 55 MAPKs 55 LRP6 55 ERK pathway 55 proNGF 55 glucocorticoid receptor 55 μ opioid receptor 55 aT cell 55 substrate specificity 55 PTP1B 55 Integrins 55 morphogens 55 SH2 B 55 renal fibrosis 55 Hh pathway 55 metalloproteases 55 cytoskeletal 55 SWI SNF 55 c myc 55 mice lacking 55 amyloid fibrils 55 vesicle formation 55 paracrine 55 coexpression 55 mTOR signaling pathway 55 receptor gene 55 RUNX3 55 calcium homeostasis 55 ARF1 55 esterase 55 synaptic transmission 55 Topoisomerase II 55 hydroxylation 55 JAZ proteins 55 perivascular 55 centrioles 55 lipid homeostasis 55 cyto 55 6S RNA 54 PPAR gamma 54 histone acetylation 54 trypanosome 54 primary cilia 54 phosphatidylinositol 3 54 DLX5 54 cyclin E 54 PDGF receptor 54 trypsin 54 neural precursors 54 dopamine synthesis 54 provirus 54 signal transduction cascade 54 Th2 immune 54 hyperactivated 54 cyclooxygenase 2 54 c myc gene 54 reductase 54 beta amyloid peptide 54 centromeric 54 histidine kinase 54 tubulin 54 striatal neurons 54 demethylation 54 Oct4 54 Smurf1 54 RNAi pathway 54 mammary epithelial cells 54 dysregulated 54 KIAA# 54 VHL gene 54 tyrosine phosphatase 54 interleukin 1beta 54 lysyl oxidase 54 Schwann cell 54 messenger molecule 54 oncogenic mutations 54 carboxyl terminal 54 astrocytic 54 enterocytes 54 fatty acid synthesis 54 transcriptional machinery 54 RNA binding 54 mRNA splicing 54 plectasin 54 acid phosphatase 54 metabolizing enzymes 54 Kv#.# 54 HBx 54 topoisomerase II 54 gene transcription 54 receptor PPAR 54 S#A# [002] 54 proinflammatory cytokine 54 epigenetic modification 54 hypothalamic 54 endonuclease 54 endosomal 54 neurotransmitter receptor 54 glioma cells 54 NFκB 54 nicotinic acetylcholine receptor 54 CD8 cells 54 miR #b [002] 54 adipogenesis 54 adipocyte 54 catalytic subunit 54 cytokine 54 cell signaling pathways 54 heterochromatic 54 proline rich 54 oligodendrocyte 54 thymidine kinase 54 epigenetic regulation 54 apoptotic pathway 54 ras gene 54 cathepsin B 54 globin genes 54 oxidases 54 vascular endothelial cells 54 podocytes 54 apoptotic 54 previously uncharacterized 54 secretase 54 neurofilament 54 proinflammatory 54 HEK# cells 54 transgene expression 54 gene inactivation 54 Kir#.# 54 Hh 54 telomerase reverse transcriptase 54 FGFR1 54 serine proteases 54 polyamine 54 ErbB2 54 interferon γ 54 histone methyltransferase 54 Atoh1 54 prolyl 54 VEGF receptor 54 synaptogenesis 54 RNA splicing 54 neurone 54 MEFs 54 IRF6 54 ERa 54 S#K# 54 phosphatase 54 circadian clock genes 54 C1q 54 coagulation cascade 54 NR2B subunit 54 metazoan 54 tumor metastasis 54 tumor stroma 54 RNA transcription 54 invadopodia 54 protein tyrosine kinase 54 p#/CBP 54 dopamine signaling 54 autophagic 54 primary cilium 54 PcG 54 clonal expansion 54 keratinocyte 54 Activating mutations 54 transcriptional repression 54 unicellular organism 54 amyloid formation 54 CHD7 54 TORC1 54 survivin 54 cyclin dependent kinase 54 transcriptional regulation 54 endocytic 54 thymidylate synthase TS 54 MDR1 54 epigenetic alterations 54 transferrin receptor 54 NFkappaB 54 Dpp 54 synthetase 54 NR#A# 54 evolutionary conserved 54 splenocytes 54 PGC 1alpha 54 neuroligins 54 monocytes macrophages 54 leukocyte recruitment 54 NS5A 54 mRNA expression 54 inverse agonist 54 FGF receptor 54 glial 54 constitutively activated 54 protein misfolding 54 HDACs 54 bradykinin 54 receptor subunit 54 proteolytic activity 54 TLE3 54 transcriptional activity 54 TGFb 54 Skeletal muscle 54 Nup# 54 DNMT1 54 pharmacological inhibition 54 SETDB1 54 misregulated 54 receptor tyrosine kinase RTK 54 acetylation 54 Cyclin D1 54 p# Shc 54 neuronal migration 54 kinesin motor 54 receptor CXCR4 54 membrane protein 54 bronchial epithelial cells 54 RRM1 54 palytoxin 54 PI3K AKT 54 caveolae 54 PP2A 54 NKT cells 54 neural progenitor cells 54 cytoskeletal protein 54 fibril formation 54 Hox gene 54 thrombospondin 54 neuroinflammatory 54 GATA1 54 TXNIP 54 fusogen 54 Tbx5 54 Notch pathway 54 mechanotransduction 54 Cdx2 54 alpha secretase 54 KLF2 54 iNOS 54 GPC5 54 MeCP2 54 missense mutation 54 dynamin 54 dynactin 54 airway epithelial 54 inhibiting COX 54 S nitrosylation 54 ACVR1 54 SOD2 54 hammerhead ribozyme 54 progranulin gene 54 Phylogenetic analysis 54 enkephalin 54 activated macrophages 54 Polycomb proteins 54 TSC1 54 proximal tubular 54 synovial cells 54 H#K# [002] 54 PcG proteins 54 mitotic progression 54 mesolimbic 54 potent inhibitors 54 TGF beta signaling 54 outer membrane proteins 54 chemotaxis 54 lipid rafts 54 CpG island 54 ErbB4 54 acinar 54 homodimers 54 nucleolin 54 FGF2 54 JAK STAT signaling 54 experimental autoimmune encephalomyelitis 54 amino terminal 54 adrenergic receptors 54 receptor signaling 54 heterodimer 54 cAMP dependent 54 Akt 54 MEF2 54 PPAR alpha 54 HipA 54 MiRNAs 54 GCN2 54 processive 54 dephosphorylation 54 topoisomerases 54 inhibitory 54 SIR2 gene 54 ABCG2 54 HER2 neu 54 downregulating 54 endosymbiont 54 serotonin receptor 54 aryl hydrocarbon receptor 54 IGF1 54 vitamin D receptor VDR 54 microRNAs 54 ESR1 54 post transcriptional 54 regulated kinase ERK 54 chemoresistance 53 downregulates 53 lymphangiogenesis 53 elastase 53 misfolded 53 phospholipase 53 AT1R 53 chromosomal regions 53 PGE2 53 PPARs 53 noncoding RNA 53 GABAergic neurons 53 lacZ 53 mitotic spindles 53 DNA demethylation 53 cyclopamine 53 SIRT6 53 neuronal signaling 53 motoneurons 53 Mice lacking 53 glutamatergic 53 CDK4 53 MECP2 gene 53 NADPH 53 IL 1beta 53 peptide inhibitors 53 mucins 53 Her-2/neu 53 M2 macrophages 53 unmutated 53 breast epithelial cells 53 FLT3 53 secreted proteins 53 hydroxylase 53 matrix metalloproteinases MMPs 53 ß1 53 HPA axis 53 NF kB 53 TGF β1 53 FLT3 kinase 53 mineralocorticoid 53 BCR ABL 53 dimeric 53 cellular metabolism 53 oncogenic transformation 53 cyclic AMP 53 ribonuclease 53 torsinA 53 NAc 53 isoforms 53 serotonin transporter 53 Dopaminergic 53 Abeta peptide 53 huntingtin protein 53 serine protease 53 erythrocyte 53 hypermethylation 53 transmembrane domains 53 TORC2 53 Ago2 53 S6K 53 Mutant mice 53 proteins