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(Click for frequent words.) 75 transgene expression 75 CD#c 73 transduced 72 hTERT 72 PBMCs 72 alveolar epithelial cells 72 transfected 72 lymphoid cells 71 HepG2 cells 71 downregulated 71 cells transfected 71 HEK# cells 71 immunoreactivity 71 EGFP 70 transgenic mice expressing 70 mRNA transcripts 70 murine 70 mRNA expression 70 annexin V 70 Immunohistochemical analysis 70 constitutively 70 proteolytic cleavage 70 IFN gamma 70 DNMT1 70 splenocytes 70 IFN γ 70 apical membrane 70 MDCK cells 70 explants 70 PC3 cells 70 coexpression 69 Western blotting 69 LNCaP cells 69 TGF ß 69 CD# + [001] 69 VSV G 69 MEFs 69 E#F# 69 overexpressing 69 bronchial epithelial cells 69 CD#b 69 peripheral blood mononuclear 69 prostate epithelial cells 69 P selectin 69 lysates 69 pDCs 69 iNOS 69 TGF beta1 69 thymocytes 69 cellular prion protein 69 somatostatin 69 immunostaining 69 effector function 69 glycosylated 69 glioma cells 69 xenograft tumors 69 lytic 69 virulence genes 69 hepatoma 69 stably transfected 69 CTLs 69 lung fibroblasts 69 CCR7 69 CHO cells 69 TNFa 69 pDC 69 thymic 68 CCL# 68 glioblastoma cells 68 ^ sup #m 68 hippocampal neurons 68 trophoblasts 68 PrPSc 68 Foxp3 68 PC# cells 68 Fig. 1D 68 supernatants 68 gene rearrangements 68 CD# expression [001] 68 tumorigenicity 68 constitutively expressed 68 adipogenic 68 enzymatic activity 68 vimentin 68 constitutively active 68 oncogenic transformation 68 wildtype 68 IgG1 68 HCV replication 68 C#BL 6 mice 68 Stat1 68 hematopoietic cells 68 MTT assay 68 trophoblast cells 68 fibroblast 68 FasL 68 transmembrane protein 68 VEGFR1 68 fluorescence intensity 68 outer membrane proteins 68 phagocytosis 68 homodimer 68 Supplementary Fig 68 potent inhibition 68 IL 1ß 68 vascular endothelial cells 68 IL 1beta 68 ERK activation 68 viral antigen 68 neuroblastoma cells 68 microglial activation 68 Cre recombinase 68 MDR1 68 Rab5 68 cDNAs 68 FUS1 67 Leydig cells 67 splice variants 67 activin 67 CD8 + 67 Annexin V 67 cisplatin resistant 67 siRNA knockdown 67 xenografts 67 SIRT2 67 erythrocytes 67 leukemic cell 67 Fas ligand 67 ERK1 2 67 transgenic rats 67 EGF receptors 67 Rap1 67 alternatively spliced 67 midgut 67 PAX5 67 Jhdm2a 67 luciferase reporter 67 nanomolar 67 osteoblast 67 replicon 67 binding affinities 67 mature dendritic cells 67 equimolar 67 c MYC 67 phagocyte 67 CEACAM1 67 cytokine signaling 67 neurite outgrowth 67 antiproliferative activity 67 EGFRvIII 67 MAP kinase 67 cathepsin B 67 plasmacytoid dendritic cells 67 tyrosine phosphorylation 67 keratinocyte 67 H#K#me# 67 Htt 67 lysate 67 mRNA molecules 67 IL 1β 67 RANTES 67 ERK signaling 66 mononuclear cells 66 cyclin E 66 paralogs 66 proto oncogene 66 ChR2 66 immunoreactive 66 XL# inhibits 66 peptide antigens 66 mutant alleles 66 epithelial tumors 66 TNF α 66 chemotactic 66 interferon γ 66 mutant proteins 66 micronuclei 66 TGF ß1 66 isoenzymes 66 GLUT4 66 unmutated 66 PTPN# 66 β1 66 P cadherin 66 inducible 66 beta actin 66 pertussis toxin 66 retroviral vector 66 GLI1 66 granulocytes 66 deficient mice 66 virions 66 breast epithelial cells 66 transfection 66 cytosolic 66 breast carcinomas 66 TNFalpha 66 ouabain 66 #T# L1 66 cell lysates 66 astrocytic 66 Clusterin 66 nucleated cells 66 thymocyte 66 SOCS3 66 antisense inhibition 66 substrate specificity 66 synuclein 66 mesothelin 66 heterozygotes 66 #β estradiol 66 adenoviral 66 p# activation 66 gene amplification 66 IFN ß 66 cDNA library 66 β cells 66 transcriptional repressor 66 induced apoptosis 66 myocytes 66 soluble receptor 66 colon carcinoma 66 MDSCs 66 androgen receptor AR 66 lysosomal 66 isoenzyme 66 skin fibroblasts 66 uPAR 66 IGF 1R 66 motoneurons 66 mice lacking 66 EBNA1 66 transferase 66 FLT3 66 transfection efficiency 66 microglial 66 oncoprotein 66 apoptotic cells 66 BALB c mice 66 CLL cells 66 qRT PCR 66 isogenic 66 effector memory 66 Notch1 66 β actin 66 cellularity 66 inhibitory effects 66 proteolysis 66 deacetylation 66 methylated DNA 66 dinucleotide 66 autophagic 66 neutralizing antibody responses 66 cytosol 66 tumoral 66 oligomerization 66 STAT1 66 ectopic expression 66 transiently transfected 66 siRNA mediated 66 miRNA expression 65 myeloma cells 65 homodimers 65 CD1d 65 Arabidopsis plants 65 myoblasts 65 shRNAs 65 bone marrow stromal cells 65 survivin 65 isotype 65 pRb 65 cell lysis 65 acinar 65 dimeric 65 CXCL# 65 TUNEL 65 monocyte 65 HSCs 65 sphingolipid 65 costimulatory 65 multinucleated 65 replicase 65 phagocytic cells 65 tumor antigen 65 nucleotide substitutions 65 lung epithelial cells 65 T lymphocyte 65 zebrafish embryos 65 DRG neurons 65 C. albicans 65 polymerases 65 MyoD 65 β catenin 65 catenin 65 hematopoietic progenitors 65 HbF 65 Cyclin D1 65 Jurkat cells 65 fibroblast cells 65 Ki# 65 morphogen 65 cytotoxicity assays 65 cDNA 65 PGCs 65 TTR gene 65 Corynebacterium 65 dsRNA 65 mitochondrial respiration 65 Nedd4 65 innate immune responses 65 TIMP 1 65 VEGFR2 65 GAPDH 65 Fig. 3a 65 chemokine receptor 65 IL #p# 65 serum antibodies 65 cDNA libraries 65 neoplastic cells 65 tumor xenografts 65 intratumoral 65 immunofluorescence microscopy 65 recombinants 65 p#Kip# 65 colocalization 65 miR #a [001] 65 MMP9 65 K#R [002] 65 N Myc 65 IFN g 65 hepatocytes 65 gene inactivation 65 myofibroblasts 65 immunized mice 65 lacZ 65 short hairpin RNAs 65 amplicons 65 cytologically 65 umbilical vein 65 IgG antibodies 65 overexpressing cells 65 COL#A# 65 intestinal epithelial cells 65 colorectal carcinoma 65 interleukin IL -# 65 kDa protein 65 antiapoptotic 65 CD8 T cell 65 CagA 65 anti CD3 65 microvascular endothelial cells 65 immunoblotting 65 MT1 MMP 65 intracellular bacteria 65 μg ml 65 microvessel density 65 hypermethylated 65 TAp# 65 ubiquitinated 65 tumorigenic 65 annexin 65 monomeric 65 perivascular 65 short hairpin RNA 65 cytotoxicity 65 FGFR3 65 BRAF protein 65 RRM1 65 IGFBP7 65 adenylate cyclase 65 NKX#.# 65 EGFR protein 65 nucleolin 65 cytokine receptor 65 Fig. 1c 65 cytoplasmic domain 65 CD4 + T lymphocytes 65 aminopeptidase 65 endostatin 65 mammary cells 65 mesenchymal cells 65 neutralizing antibody 65 inflammatory cytokine 65 mediated inhibition 65 exocytosis 65 NOD mice 65 Vpu 65 BMP2 65 peroxidase 65 granzyme B 65 beta subunit 65 fig. S2 65 EphB4 65 prostate carcinoma 65 adipose cells 65 metaphase 65 immunodeficient mice 65 humoral immunity 65 endosomal 65 striated muscle 65 activating mutations 65 RKIP 65 caveolin 1 65 missense mutation 64 Tubulin 64 leukemic stem cells 64 vitro cytotoxicity 64 biodistribution 64 isotypes 64 pyruvate kinase 64 operon 64 serine threonine kinase 64 Flt3 64 homogenates 64 intestinal epithelium 64 CDK4 64 #ß 64 ERBB2 64 dephosphorylation 64 osteoclast 64 mutant SOD1 64 N. benthamiana 64 leukemic cells 64 cultured cells 64 Overexpression 64 IL #E 64 proteinase 64 Th1 cells 64 immunofluorescence staining 64 granulocyte 64 nucleolar 64 cell lysate 64 subcellular compartments 64 HER2/neu 64 chromosomal aberrations 64 CYP#B# 64 downregulation 64 TMPRSS2 ERG 64 beta1 integrin 64 hepatocyte 64 focally 64 neurofilament 64 CD# CD# 64 ATPase activity 64 uninfected cells 64 PrP 64 TRAIL induced apoptosis 64 adrenocortical 64 RhoA 64 enterocytes 64 deletion mutant 64 colorectal tumor 64 agonist induced 64 EGFR expression 64 viral proteins 64 adenoviral vector 64 TGF β 64 glomerular 64 HCV replicon 64 haematopoietic 64 induces apoptosis 64 cathepsins 64 transferrin receptor 64 LPS induced 64 Kupffer cells 64 IgG4 64 serotonin synthesis 64 4E BP1 64 RNA transcripts 64 c Fos 64 Figure 1C 64 potently inhibited 64 db db mice 64 N cadherin 64 vacuolar 64 microinjection 64 flavopiridol 64 Leydig cell 64 ovalbumin 64 shRNA 64 CXCL5 64 immunohistochemical analysis 64 PKC delta 64 MUC1 64 isoforms 64 kinase gene 64 Fig. 3b 64 mutated KRAS 64 trophoblast 64 tumor xenograft models 64 lactate dehydrogenase 64 N. gonorrhoeae 64 p# Shc 64 phosphatidylinositol 64 PCR assay 64 orthologs 64 EpCAM 64 sequence homology 64 transcriptional activation 64 GPx 64 gametocytes 64 aT cell 64 IFN α 64 S. cerevisiae 64 cholera toxin 64 5alpha reductase 64 phosphoprotein 64 CD8 T cells 64 acyltransferase 64 melanocyte 64 c Src 64 activating mutation 64 mutant p# 64 steroidogenic 64 monocytes macrophages 64 paxillin 64 viral nucleic acid 64 S. enterica 64 aneuploid cells 64 PAK1 64 null mice 64 monocyte derived dendritic cells 64 neural progenitor cells 64 MCF7 cells 64 mRNA encoding 64 TIMP 64 ERalpha 64 V#F 64 hMSCs 64 embryonal carcinoma 64 Hcrt 64 E. faecalis 64 ribonuclease 64 cardiac fibroblasts 64 mononuclear 64 vesicle fusion 64 NKT cell 64 radiosensitivity 64 microRNA molecules 64 MAPK pathway 64 apoptotic 64 immunostimulatory 64 T#I [002] 64 LRAT 64 EGF receptor 64 Cytotoxic T 64 IFNg 64 GLUT1 64 #S rRNA gene 64 basic fibroblast 64 Th2 cytokines 64 GHRH 64 microsomes 64 Tissue Factor 64 germinal center 64 missense mutations 64 urease 64 transactivation 64 ciliated 64 VE cadherin 64 upregulated 64 basolateral 64 mRNA translation 64 methylation patterns 64 syngeneic 64 erythrocyte 64 EphA2 64 heterochromatic 64 gastric mucosa 64 cytokeratin 64 TrkB 64 defensin 64 mutant allele 64 miR #b [001] 64 hematopoietic progenitor cells 64 resistant mutants 64 HIF 1a 64 3'UTR 64 mitogen activated protein kinase 64 EGFR receptor 64 Neutrophil 64 inhibitory activity 64 Aâ 64 inhibitory receptor 64 TGF alpha 64 SDS PAGE 64 p# MAPK 63 effector functions 63 nutlin 3a 63 Akt activation 63 carcinoembryonic antigen 63 hnRNP 63 receptor subtypes 63 mycobacterial 63 suppressor gene 63 actin polymerization 63 Cyclin E 63 HIF 1alpha 63 ADAMTS# 63 rhIL 7 63 lesional 63 glioblastoma tumors 63 cytokine secretion 63 cells hESCs 63 V#F mutation 63 specific CD8 + 63 Prox1 63 cyclic AMP cAMP 63 CD4 + CD# 63 microsomal 63 HER2 neu 63 occludin 63 mutant worms 63 TGF β1 63 viral nucleic acids 63 caspase activation 63 coding genes 63 endonuclease 63 tryptase 63 ovarian carcinoma 63 FSH receptor 63 1alpha 63 thymidine 63 busulfan 63 activated macrophages 63 monocyte chemotactic protein 63 undifferentiated hESCs 63 ENaC 63 CpG 63 leukocyte 63 plastid 63 Fig. 2A 63 PDGF receptor 63 centromeric 63 cyclin B1 63 oncoproteins 63 orthotopic 63 HERV 63 NKG2D 63 radiolabeled 63 tumor specific antigen 63 ENMD # 63 transgenic mouse models 63 polyclonal 63 epidermidis 63 Treg cell 63 immunological responses 63 serine protease 63 transmembrane receptor 63 stromal cells 63 homozygotes 63 cysteine protease 63 fig. S1 63 factor HGF 63 MYCN 63 chondrocytes 63 xenograft models 63 immunoglobulin G 63 FKBP# 63 ex vivo 63 heterozygote 63 p# NTR 63 F actin 63 NOD SCID mice 63 ACh 63 plasminogen 63 inducible nitric oxide synthase 63 NF kappaB activation 63 thymidylate synthase TS 63 cell adhesion molecule 63 lymphocyte counts 63 cells overexpressing 63 glycolipids 63 #F FDG 63 TNFR1 63 germline mutation 63 Fig. 4a 63 FGF2 63 transgene 63 MAb 63 Gleevec resistant 63 keratinocytes 63 6S RNA 63 effector molecules 63 murine models 63 murine model 63 bcl 2 63 ERK2 63 5 HT2C receptor 63 DNA demethylation 63 telomerase reverse transcriptase 63 histologically 63 pro apoptotic proteins 63 vitro experiments 63 immune deficient mice 63 adrenoceptor 63 DLC1 63 hepatocellular carcinomas 63 osteoblastic 63 transmembrane 63 p# alpha [001] 63 fluorescently tagged 63 neurotrophin 63 mammalian cells 63 M1 muscarinic 63 cytolytic activity 63 GRP# 63 PDGF B 63 circulating endothelial 63 thymidine kinase 63 fluorescently labeled 63 thioredoxin 63 carboxyl terminal 63 Histological examination 63 phagocytes 63 CD4 + cells 63 LRP6 63 secretory pathway 63 nanomolar range 63 elastase 63 depolarization 63 IGFBP 3 63 humoral responses 63 TGF beta pathway 63 NSCLC tumors 63 cAMP signaling 63 selectively inhibited 63 BCL2 63 Alkaline Phosphatase 63 induce apoptosis 63 colony stimulating factor 63 effector cells 63 polypeptides 63 lymphoid organs 63 isoform 63 ErbB2 63 primordial germ cells 63 subcellular localization 63 miR #a [002] 63 pleiotropic 63 malignant transformation 63 p# deficient 63 operons 63 alkaline phosphatase ALP 63 GABAergic neurons 63 heterologous 63 nM 63 hypermethylation 63 PHD2 63 FGFR4 63 lymphoid tissue 63 Anticalins ® 63 malignant prostate 63 CD# + [002] 63 nAChR 63 Gram stain 63 folate receptor 63 ribosomal DNA 63 Cathepsin B 63 mediated apoptosis 63 Immunohistochemical staining 63 KLF4 63 lentiviral vector 63 prostaglandin E2 PGE2 63 telomerase inhibition 63 tau phosphorylation 63 allelic variants 63 rRNA 63 Secretase 63 enzymatically active 63 ER alpha 63 CXCR4 expression 63 immunodominant 63 FDG uptake 63 RQ PCR 63 pyrimidines 63 Upregulation 63 intracellular signaling 63 clonogenic 63 differential gene expression 63 tumor necrosis 63 polymorphonuclear leukocytes 63 biotinylated 63 cytoplasmic 63 BMP signaling 63 redox active 63 autoreactive 63 ERK phosphorylation 63 megakaryocytes 63 globin gene 63 basophils 63 cultured neurons 63 Th2 immune 63 epithelia 63 miR #b [002] 63 Fig. 1C 63 globin 63 lymphoid 63 embryoid bodies 63 costimulatory molecules 63 RNA polymerases 63 S. Typhimurium 63 estrogen receptor alpha 63 leucocytes 63 HLA DR 63 DNase 63 Fibroblast 63 Lymphocytes 63 microRNA miR 63 pancreatic endocrine 63 retinal neurons 63 transgenic mouse model 63 miRs 63 cortical neurons 63 lentiviral vectors 63 estrogen receptor beta 63 human ESCs 63 alpha subunit 63 neuropilin 63 epithelial cell 63 constitutively activated 63 luciferase 63 ß amyloid 63 phospholipase 63 atherosclerotic lesions 63 LHRH receptors 63 leukocytosis 63 t# c# CLA 63 chemotaxis 63 neuroblastoma tumors 63 ribosomal protein 63 Eg5 63 ligand binding 63 P. gingivalis 62 eotaxin 62 5' triphosphate 62 locomotor activity 62 HDAC6 62 oxidative phosphorylation 62 #beta estradiol 62 humoral immune responses 62 ERK pathway 62 IGFBP 62 Dpp 62 procaspase 3 62 PCR amplified 62 pro angiogenic 62 Androgen receptor 62 Pgp 62 WT1 62 TRAIL R2 62 μM 62 dose dependently 62 S#A# [002] 62 viral antigens 62 plasmacytoid 62 antigen binding 62 insertional mutagenesis 62 secretory 62 pDNA 62 eNOS 62 glucocorticoid receptor 62 costimulation 62 normal prion protein 62 PDGFR 62 neoplastic 62 muscarinic receptor 62 Shp2 62 ovarian follicles 62 B lymphocyte 62 CXCR4 62 cardiomyocyte 62 CD# expressing 62 differentially expressed genes 62 GSTP1 62 MAPKs 62 PTHrP 62 VEGF receptor 62 osteogenic 62 PKC isoforms 62 E1A 62 TET2 62 monocytic 62 Phosphorylation 62 T#M 62 Aβ 62 immunofluorescence 62 bispecific 62 CD8 cells 62 CpG ODN 62 MDM2 62 glycolytic 62 Fibroblasts 62 lymphoblasts 62 mitogen 62 osteogenic differentiation 62 IGF1R 62 MMP# 62 erythropoiesis 62 eukaryotic cells 62 overexpress 62 posttranslational modification 62 bispecific antibody 62 Microarray analysis 62 proinflammatory mediators 62 intratumoral injection 62 GM CSF granulocyte 62 secretase 62 astrocyte cells 62 RT qPCR 62 ERa 62 beta amyloid peptide 62 ganglioside 62 Fig. 2B 62 protein tyrosine phosphatase 62 mammaglobin 62 antibody titers 62 muscle actin 62 CDK inhibitor 62 downregulate 62 antisera 62 Chinese hamster ovary 62 NMDAR 62 RUNX3 62 quasispecies 62 P gp 62 metabolizing enzyme 62 prion protein PrP 62 tumor stroma 62 neural cells 62 PGE2 62 VCAM 1 62 cytidine 62 intronic 62 Trp p8 62 immunoblot 62 antitumor efficacy 62 GABAergic interneurons 62 monoclonal 62 endocytic 62 milatuzumab 62 AAV2 62 replicative 62 adrenal cortex 62 pancreatic islet 62 CaM 62 NFκB 62 ectodomain 62 immunohistochemical staining 62 humoral immune response 62 avidin 62 lysine residues 62 indirect immunofluorescence 62 effector T 62 Akt1 62 beta globin gene 62 cytoprotective 62 JCV 62 histone acetylation 62 polyamine 62 biochemical assays 62 lipoxygenase 62 carcinoids 62 antigenic epitopes 62 AT1R 62 chemiluminescence 62 β amyloid 62 MnSOD 62 ß catenin 62 phospho 62 thyrotropin 62 serine threonine 62 bleomycin 62 antibody secreting cells 62 allergic airway inflammation 62 E selectin 62 melanoma tumors 62 Fig. 2a 62 mammary epithelial cells 62 TGF b 62 cytochrome c oxidase 62 62 gut mucosa 62 polypeptide 62 hypoxia induced 62 Abeta# 62 mouse fibroblasts 62 exonuclease 62 AGTR1 62 EZH2 62 mtDNA mutations 62 immunohistochemical 62 PAM4 62 azacytidine 62 adipocyte 62 inhibited tumor 62 basal cells 62 K ras mutations 62 intraperitoneal injection