Related by context. All words. (Click for frequent words.) 81 allele 75 mutations 74 haplotype 74 genotypes 74 polymorphisms 74 heterozygous 73 polymorphism 72 mutation 72 genotype 70 homozygous 70 phenotype 70 homozygotes 69 loci 69 haplotypes 68 genes 68 genetic variant 68 gene variants 68 intron 68 gene 67 heterozygotes 67 MTHFR 67 phenotypes 67 isoforms 67 #q# [001] 67 homozygosity 66 mutant allele 66 SNPs 66 rs# [004] 66 missense mutations 66 rs# [003] 65 mtDNA 65 germline mutations 65 chromosome #q# [001] 65 nucleotide 65 orthologs 65 gene mutations 65 allele frequencies 65 allelic 65 mutated gene 65 homozygote 64 C#Y 64 CNVs 64 haplogroups 64 subtype 64 heterozygosity 64 homologs 64 subtypes 64 gene variant 64 5 HTTLPR 64 genetic variants 64 rs# [002] 64 FGFR2 63 PTPN# 63 isoform 63 receptor gene 63 X chromosome 63 susceptibility genes 63 allelic variants 63 ApoE 63 heterozygote 63 FMR1 63 #q# [002] 63 genes encoding 63 gene mutation 63 ABCB1 63 D. melanogaster 63 MC1R gene 63 mosaicism 63 genetic variation 63 linkage disequilibrium 63 chromosome 63 SLC#A# [002] 62 chromosomal 62 APOE4 62 GSTM1 62 G allele 62 apolipoprotein E gene 62 APOC3 62 rs# [001] 62 chromosomal alterations 62 haplogroup 62 FMR1 gene 62 single nucleotide polymorphism 62 clades 62 mutant alleles 62 variant alleles 62 APOE gene 62 proband 62 genotypic 62 diploid 62 penetrance 62 APOE e4 62 miRNAs 61 mRNA expression 61 TT genotype 61 mutant gene 61 K#R [002] 61 gene encoding 61 functional polymorphism 61 CDKN2A 61 MSH2 61 chromosomal rearrangements 61 MnSOD 61 OPRM1 gene 61 intergenic 61 genetic mutations 61 A. thaliana 61 paralogs 61 intronic 61 phenotypically 61 HLA genes 61 #p#.# [001] 61 IL#B 61 MHC genes 61 chromosomal regions 61 MLH1 61 germline 61 monozygotic twins 61 #q#.# [002] 61 APOE 61 karyotype 61 transgene 61 methylation 61 spontaneous mutation 61 genetic polymorphisms 61 CagA 61 coding sequences 61 DRD2 61 K#N 61 PALB2 61 deleterious mutations 61 missense mutation 61 VNTR 61 chromosome #q# [002] 61 genetic mutation 61 virulence genes 60 MTHFR gene 60 tumor suppressor gene 60 chromosomal aberrations 60 indels 60 dinucleotide 60 alternatively spliced 60 genes predisposing 60 constitutively 60 codons 60 CYP#D# 60 Supplementary Fig 60 IgA deficiency 60 phenotypic variation 60 QTLs 60 HLA B# 60 gene locus 60 segmental duplications 60 dopamine transporter gene 60 dizygotic 60 autosomal 60 lineages 60 germline mutation 60 PON1 60 Alu elements 60 susceptibility gene 60 ERBB2 60 heritable 60 major histocompatibility complex 60 APOE ε4 60 apolipoprotein E 60 homologue 60 mice lacking 60 sporadic ALS 60 ultraconserved elements 60 APOE4 gene 60 monozygotic 60 #q#.# [001] 60 valine 60 BDNF gene 60 overexpression 60 homolog 60 nucleotide sequence 60 apoE4 59 CCR5 delta# 59 IFN gamma 59 KRAS mutations 59 pseudogenes 59 EGFR gene 59 enzymatic activity 59 gene polymorphisms 59 microdeletions 59 genetic variations 59 TP# mutation 59 CFH gene 59 synuclein 59 exon 59 gene expression patterns 59 variant allele 59 microdeletion 59 Rap1 59 MLL gene 59 S. cerevisiae 59 LIS1 59 somatic mutations 59 transfected 59 transgene expression 59 globin genes 59 mRNA transcripts 59 miRNA expression 59 recessive genes 59 microcephalin 59 chromosomal deletions 59 CAG repeats 59 spontaneous mutations 59 centromeres 59 microsatellite markers 59 evolutionarily conserved 59 CYP#B# 59 ApoE gene 59 COMT gene 59 recessive gene 59 V#F mutation 59 cyclin E 59 aneuploidy 59 PTEN mutations 59 CDH1 59 activating mutations 59 IGFBP 59 CHEK2 59 imprinted genes 59 COL#A# 59 mutated genes 59 LPA gene 59 selfing 59 CGG repeats 59 cytosine 59 inherited mutations 59 IGF2 59 MECP2 gene 58 cyclin 58 ApoE4 58 dimers 58 tumor suppressor genes 58 GSTP1 58 cadherin 58 inbred strains 58 genomes 58 genetic polymorphism 58 exons 58 autosomal dominant 58 chromosomal rearrangement 58 rDNA 58 TCF#L# gene 58 chromosome #p# [001] 58 Foxp3 58 UGT#B# 58 GSTT1 58 ZNF# 58 mtDNA mutations 58 leptin receptor 58 methylation patterns 58 splice variants 58 C#BL/#J 58 GABRA2 58 NF1 gene 58 UGT#A# * 58 HLA DRB1 * 58 IKZF1 58 breast carcinomas 58 recessive mutation 58 TACI mutations 58 p# mutation 58 C. neoformans 58 mitochondrial 58 X chromosomes 58 DLC1 58 autosomal recessive 58 E cadherin 58 LRRK2 gene 58 BRCA2 mutation 58 proto oncogene 58 SNP rs# [001] 58 autosomes 58 methylenetetrahydrofolate reductase 58 HPV# 58 amino acid substitutions 58 NF1 58 maternally inherited 58 serum concentrations 58 constitutively active 58 serine 58 untranslated regions 58 suppressor gene 58 TMEM#B 58 CNTNAP2 58 STAT4 58 homodimers 58 uPAR 58 HLA DQ2 58 tyrosine phosphorylation 58 unmethylated 58 de novo mutations 58 clade 58 transactivation 58 clusterin 58 NNRTI resistance 58 RASSF1A 58 EGFR mutations 58 genetic abnormalities 58 hypermethylation 58 genetic alterations 58 translocations 58 gene polymorphism 58 #p# [003] 57 cytoplasmic 57 Notch1 57 BRCA1 mutations 57 X inactivation 57 KLF4 57 CC genotype 57 dizygotic twins 57 indel 57 amplicons 57 BRCA1 gene 57 MC1R 57 TP# mutations 57 herpesviruses 57 SMAD4 57 chromosomes 57 colorectal neoplasia 57 P. falciparum 57 epitope 57 WT1 57 mRNAs 57 APOL1 57 chromosome #q#.# [001] 57 premutation 57 epigenetically 57 DRD2 gene 57 Genetic variation 57 BRCA1 57 estrogen receptor 57 outcrossing 57 #S rRNA 57 BRAF V#E 57 monophyletic 57 ApoE4 gene 57 genomic deletions 57 clonally 57 serotonin transporter gene 57 VHL gene 57 genetic loci 57 introns 57 TCF#L# 57 haploid 57 TAp# 57 cDNA 57 genetic variability 57 epistasis 57 CYP#D# gene 57 HLA molecules 57 promoter methylation 57 EBNA1 57 nucleotide substitutions 57 MAPK pathway 57 alpha synuclein gene 57 Haplogroup 57 genes CYP#C# 57 phenotypic 57 genetic markers 57 caveolin 57 miRNA genes 57 substrate specificity 57 CpG 57 BRCA mutations 57 ncRNAs 57 SORL1 57 hTERT 57 H#K#me# 57 sequence homology 57 phylogenetically 57 BARD1 57 transgenes 57 amino acid residues 57 beta globin 57 genotyped 57 neuroligins 57 HbF 57 isoenzymes 57 chromosome #q 57 DNA sequences 57 null mice 57 cDNAs 57 quantitative trait loci 57 gene expression 57 nucleotide sequences 57 TP# gene 57 MHC molecules 57 autoantibodies 57 chromosomal translocations 57 ribosomal proteins 57 CCL#L# 57 5 HTT gene 57 bacterial genomes 57 CD1d 57 glycoproteins 57 APOE allele 57 outbred 57 MYH9 gene 57 mitochondrial gene 57 serotonin transporter 57 KRAS gene 57 KIAA# 57 miR #a [001] 57 clonal 57 cytosolic 57 STAT1 57 ribosomal protein 57 LRAT 57 SLC#A# [001] 56 ciliated 56 PrP 56 epigenetic silencing 56 unmutated 56 acetylation 56 prion protein gene 56 VKORC1 56 DRD4 56 PTEN gene 56 HepG2 cells 56 phosphorylated 56 variants 56 amino acid sequence 56 IL#R 56 thymocytes 56 MyoD 56 MDM2 56 mutational 56 malignant transformation 56 RUNX3 56 orthologous 56 genomic instability 56 CCR7 56 KIF6 gene 56 E#F# 56 cyclin D1 56 cytochrome 56 ALDH2 56 wildtype 56 catenin 56 beta subunit 56 tau gene 56 SRY gene 56 SMN1 56 MLL2 56 #p#.# [002] 56 dopamine receptor gene 56 noncoding RNAs 56 downregulated 56 MAOA gene 56 OCA2 56 hypermethylated 56 BRCA2 56 K ras mutations 56 transmembrane protein 56 cysteines 56 frameshift mutation 56 GAPDH 56 activin 56 SMN2 gene 56 Homozygous 56 cystatin 56 iNOS 56 Clusterin 56 beta globin gene 56 defensin 56 HFE gene 56 RNA sequences 56 Leydig cell 56 thymine 56 hepatoma 56 Wwox 56 microglial 56 colorectal tumors 56 cytochrome b 56 HLA B 56 G#S mutation 56 dopamine D4 receptor 56 telomeric 56 karyotypes 56 HLA alleles 56 differentially expressed genes 56 recessive trait 56 #p# [001] 56 CYP#C# [002] 56 gene rearrangements 56 lymph node metastasis 56 N Myc 56 clade B 56 Polymorphisms 56 C. trachomatis 56 fig. S1 56 myostatin gene 56 cells transfected 56 gene variation 56 basal cell nevus syndrome 56 overexpressing 56 androgen receptor gene 56 S#A# [002] 56 subfamily 56 phenotypic traits 56 mRNA 56 CYP#C# * 56 intergenic regions 56 genes BRCA1 56 repeat allele 56 allele frequency 56 histone modifications 56 CHD7 56 MAOA 56 coding genes 56 neoplastic 56 hippocampal neurons 56 centromeric 56 ε4 56 PCa 56 receptor binding 56 p# mutations 56 At#g# 56 autism susceptibility genes 56 Pol IV 56 GlcNAc 56 ESR1 56 morphologically 56 adenoma 56 dysbindin 56 protein isoforms 56 SOD2 56 familial ALS 56 hepatocellular carcinomas 56 K ras gene 56 ADH1B * 56 fig. S2 56 ribosomal DNA 56 GSTM1 gene 56 monocyte 56 monogenic 56 protein encoded 56 murine 55 transcriptional repressor 55 BRCA2 gene 55 FLT3 55 genetically 55 allelic variation 55 proteins 55 polyploidy 55 lymphocyte 55 serotype 55 transcription factor 55 MGUS 55 chromosomal abnormalities 55 transgenic mice 55 serogroup 55 mitochondrial genome 55 autoantibody 55 superfamily 55 WNK1 55 breast cancer genes BRCA1 55 phosphorylation 55 SOD1 protein 55 CFTR gene 55 transcription factors 55 heritable traits 55 prognostic factor 55 KCNQ1 55 D#N 55 micro RNAs 55 C#BL 6 55 CYP#E# gene 55 NEIL1 55 GLUT1 55 ERCC1 55 transgenic mice expressing 55 somatic mutation 55 gene APOE 55 Pten 55 BRCA mutation 55 SLC#A# gene [001] 55 ABCB1 gene 55 membrane proximal 55 B. subtilis 55 Alleles 55 HNPCC 55 Jhdm2a 55 Fig. 1C 55 gene sequences 55 inhibin 55 HTLV 55 kinases 55 mitochondrial genomes 55 genome 55 amino acid sequences 55 defective gene 55 aneuploidies 55 gene expression profiles 55 H#K# [002] 55 vimentin 55 subcellular localization 55 subunit 55 piRNAs 55 synthase 55 claudin 55 apoE 55 c Myb 55 DR4 55 DRB1 * 55 EGFR mutation 55 methylated 55 eukaryote 55 CD8 + 55 microsatellite instability 55 recessive traits 55 HBV genotype 55 DNMT1 55 var genes 55 androgen receptor AR 55 HLA DRB1 55 TSC1 55 chromosome #p#.# 55 DRD4 gene 55 inducible 55 polyploid 55 ataxin 55 Plasmodium 55 RNAs 55 gene loci 55 Mus musculus 55 ErbB2 55 constitutively expressed 55 polymerases 55 aldehyde dehydrogenase 55 BRAF mutations 55 TGFBR1 * 6A 55 immunoreactivity 55 neutralizing antibody 55 nucleoli 55 CYP#C# [001] 55 familial pancreatic cancer 55 probands 55 cystatin C 55 amino acid substitution 55 phylogenetic analyzes 55 codon 55 RhoA 55 cDNA libraries 55 downregulation 55 deacetylation 55 p# [001] 55 mRNA molecules 55 MeCP2 gene 55 Li Fraumeni syndrome 55 oncogenic 55 pRb 55 K ras 55 transfected cells 55 ALK mutations 55 genomic DNA 55 microRNA molecules 55 Arabidopsis 55 genetic 55 kinase gene 55 single nucleotide polymorphisms 55 BRCA2 mutation carriers 55 HMGA2 55 heterochromatin 55 rRNA 55 NPY gene 55 tetramers 55 C1q 55 ERK2 55 erythrocytes 55 parkin gene 55 syngeneic 55 TCF4 55 PAX5 55 telomere length 55 isoenzyme 55 IGF1 55 FXTAS 55 viral strains 55 cell adhesion molecule 55 ependymomas 55 histone modification 55 ortholog 55 E selectin 55 autosomal recessive disease 55 fetal hemoglobin 55 mammary cells 55 CYP#E# 55 neuroblastomas 55 gene duplications 55 CDK4 55 Vps# 55 nucleotide substitution 55 missense 54 prion gene 54 isoleucine 54 goblet cells 54 Fig. 3a 54 paternally inherited 54 globin gene 54 CYP#A# [002] 54 APOE epsilon 4 54 medulloblastomas 54 mammary stem cells 54 trypanosome 54 BRCA1 mutation 54 SHANK3 54 epithelial tissues 54 pathogenic mutations 54 hamartomas 54 Prox1 54 MSH6 54 epigenetic mechanisms 54 gambiae 54 tumor suppressor protein 54 NRTIs 54 tyrosine kinases 54 sCJD 54 perilipin 54 ploidy 54 glycosylation 54 chromosome rearrangements 54 genetic variants associated 54 splice junctions 54 chromosome #q#.# [002] 54 transcriptional activation 54 mutant worms 54 Candida species 54 Leydig cells 54 cyclins 54 Smad3 54 glycoprotein 54 esophageal squamous cell carcinoma 54 DQB1 * 54 SOX9 54 LNCaP cells 54 polymorphic 54 monozygotic twin 54 bcl 2 54 metabolic abnormalities 54 apolipoprotein E APOE 54 EGFP 54 M. pneumoniae 54 Genetic variants 54 GBM tumors 54 homologues 54 CNTNAP2 gene 54 transgenic rats 54 protein tyrosine phosphatase 54 mammalian genomes 54 IFN alpha 54 synthases 54 mammary tumors 54 synthetase 54 kilobases 54 BRCA2 mutations 54 noncoding 54 EBV infection 54 IL# [001] 54 hypomethylation 54 STAT3 54 C. albicans 54 H. influenzae 54 progranulin gene 54 fraternal twin pairs 54 PDGFR 54 globin 54 PIK3CA 54 receptor subtypes 54 epithelia 54 modifier genes 54 alpha2 54 subfamilies 54 oxytocin receptor 54 CXCL# 54 serotypes 54 Th2 54 heterodimers 54 Th1 54 IDH2 54 differential gene expression 54 deficient mice 54 DISC1 54 centrosome 54 mutant strains 54 parkinsonism 54 LRP6 54 MYH9 54 DARPP 54 homologous chromosomes 54 estrogen receptor ER 54 GTPase 54 telomere lengths 54 transcriptome 54 coexpression 54 biotype 54 gametocytes 54 CEACAM1 54 TOP2A 54 prion strains 54 N. gonorrhoeae 54 genetic traits 54 ectopic expression 54 familial clustering 54 ORFs 54 proteolysis 54 YKL 54 heterologous expression 54 genomewide 54 promoter polymorphism 54 SE alleles 54 isogenic 54 BRAF mutation 54 Cre recombinase 54 HLA DR 54 TLR3 54 mitochondrial DNA mtDNA 54 JAK2 mutation 54 G6PD 54 lactis 54 mutated K ras 54 FasL 54 tetraploid 54 transposable elements 54 mammary cancers 54 cellularity 54 β 54 3' UTR 54 mutant protein 54 cytopathic 54 cytoplasmic tail 54 DNA methylation 54 deleterious mutation 54 melanocyte 54 Aß 54 outer membrane proteins 54 neoplasm 54 alanine 54 apolipoprotein 54 Haplotype 54 apolipoprotein E4 54 viral genome 54 kilobase 54 mutant proteins 54 non coding RNA 54 phospho 54 chromosomal DNA 54 antibody titers 54 M. genitalium 54 histone deacetylases 54 binding affinity 54 transmembrane 54 TGF β 54 HLA DRB1 SE 54 HIF 1alpha 54 histone H3 54 coinfection 54 behavioral disinhibition 54 lysine residues 54 chromosomal instability 54 retinal ganglion cells 54 melatonin receptor 54 TNF α 54 atopy 54 matrix metalloproteinase 54 TRAF1 C5 54 radial glia 54 mutant genes 54 lymphoid 54 incomplete penetrance 54 SNP rs# [002] 54 Fas ligand 54 chromosome segregation 54 RNA transcripts 54 syntaxin 54 dimerization 54 NFKBIA 54 lymphocytic 54 conserved sequences 54 simian immunodeficiency virus 54 T2DM 54 lymphoid cells 54 subclinical 54 fig. S4 54 pDCs 54 EGFR 54 Heterozygous 54 BMP receptor 53 GISTs 53 HDL2 53 estrogen receptor alpha 53 MIF gene 53 testis 53 MC4R gene 53 HLA gene 53 amyloidogenic 53 generalized vitiligo 53 HNSCC 53 ENaC 53 kinase 53 meiotic 53 granulocytes 53 short hairpin RNA 53 tRNA synthetase 53 c KIT 53 NKT cells 53 Activating mutations 53 Rac1 53 genetic alteration 53 polyadenylation 53 ApoE4 allele 53 EZH2 53 prostate cancer CaP 53 palmitoylation 53 DRB1 53 brucei 53 Fig. 3b 53 3'UTR 53 NPM1 mutations 53 serine threonine kinase 53 CYP# [002] 53 R#W [002] 53 STK# [002] 53 GPR# [002] 53 NAFLD 53 pea aphid 53 ER alpha 53 TGF ß 53 recombinants 53 UTRs 53 upregulated 53 RAR beta 53 RNA viruses 53 microRNA expression 53 ubiquitination 53 CD#b 53 endostatin 53 COMT 53 genetic trait 53 tRNAs 53 HMGA2 gene 53 TNFR1 53 gene amplification 53 CYP#C# gene 53 cell adhesion molecules 53 poorer prognosis 53 PB1 F2 53 taxa 53 Skp2 53 somatostatin 53 MECP2 53 mitochondrial genes 53 BCL#A 53 GNAQ 53 serotonin receptor 53 NRTI resistance 53 atypical hyperplasia 53 operon 53 telomerase reverse transcriptase 53 Cx# [001] 53 TMPRSS2 ERG 53 proteolytic cleavage 53 capsular polysaccharide 53 presenilin 53 C#BL 6 mice 53 isotypes 53 β amyloid 53 cytokeratin 53 ApoB 53 methylated DNA 53 metaplasia 53 adenylate cyclase 53 Pin1 53 lymph node metastases 53 homology 53 causal variants 53 IGFBP 3 53 mutant mice 53 receptor signaling 53 leucine zipper 53 survivin 53 IFN γ 53 DICER1 gene 53 interferon IFN 53 Akt 53 heterochromatic 53 hydroxylase 53 non coding RNAs 53 breast carcinoma 53 lysosomal 53 LKB1 53 Phylogenetic analysis