ghrelin chitinase IP3 hypersensitive habenular countyhas intracellular phosphofructokinase cytokines ferroportin histamine RasGAP Presenilin norepinephrine upregulate allosteric CSNB1 neurotransmitter osteoblast bisphosphoglycerate glycoalkaloids excitability Glucokinase luciferase cyclase upregulated MyoD autophagic curculin DDAH oxygenase gliotransmission Ghrelin bifunctional aromatase GABA NFQundB serotonin Leptin