Cre Nudix phage ribohydrolase require hQund3 CD33 Ubiquitin homeodomain ribonucleoside caviae recombinase UAS HOXD tripeptide ZFN VSGs exon display tetraspanins streptavidin oligonucleotide NQfs IS2404 NEDD8 placegetters selected mRNA multicomponent applications microRNA gammaQund0 methylates noncovalently mutagenesis recombinant cDNA