Related by context. All words. (Click for frequent words.) 69 TTR gene 69 selective inhibition 68 androgen receptor AR 68 CCR2 68 selectively inhibits 67 MAPK pathway 67 E#F# 67 c MYC 67 TRAIL induced apoptosis 66 mediated inhibition 66 CYT# potent vascular disrupting 66 myeloproliferative diseases 66 FGFR2 66 antiapoptotic 66 Cyclin E 66 endogenous ligands 66 c MET 66 Janus kinase 66 targeting CD# 66 preclinically 65 5 HT2A serotonin 65 Epidermal Growth Factor Receptor 65 Androgen Receptor 65 phosphate S1P 65 PI3K Akt 65 Wnt signaling pathway 65 cathepsins 65 mda 7 65 potent inhibition 65 anti amnesic 65 antiproliferative effects 65 COX2 65 FLT3 65 CCR1 65 neurotrophic 65 immune modulating 65 induces apoptosis 65 phosphatidylinositol 3 65 potent inhibitors 65 Clusterin 65 apoptosis inducing 65 protein tyrosine phosphatase 1B 65 tubulin inhibitor 65 PC# cells 65 missense mutations 64 PDGFR 64 FGFR 64 antitumor effects 64 pathological hallmark 64 Lyn kinase 64 Symadex 64 M1 muscarinic 64 CCR9 64 DNA methyltransferase inhibitors 64 retinoid X 64 pan HDAC inhibitor 64 xenograft models 64 colon carcinoma 64 mGluR2 NAM 64 transgenic mouse model 64 GSK3B 64 oncogenesis 64 serine protease 64 kinase inhibition 64 neurite outgrowth 64 ENMD # 64 GRP# 64 NKG2D 64 HDAC enzymes 64 endoplasmic reticulum stress 64 AMPK activators 64 irreversible inhibitor 64 cyclooxygenase 2 64 ERK1 2 64 inhibitory receptor 64 protein kinase C 64 JAK inhibitors 64 K ras mutations 64 miR #a [001] 64 pro apoptotic 64 eIF 4E 64 Aurora kinase 64 pDCs 64 antiangiogenic 64 KRAS oncogene 64 deacetylation 64 VEGF receptor 64 HIF 1α 64 pathophysiological effects 64 pharmacodynamic biomarkers 64 cMET 64 mTOR mammalian target 64 GMX# 64 demethylating agents 64 neuronal dysfunction 64 cyclin E 64 Factor Receptor 64 MEK ERK 63 cyclin dependent kinase inhibitor 63 eotaxin 63 factor receptor FGFR 63 Dysregulation 63 antisense inhibitors 63 Eg5 63 lysophosphatidic acid LPA 63 glycogen synthase kinase 63 selective antagonists 63 tumor suppressive 63 pleiotropic 63 receptor tyrosine kinase 63 Protein Kinase C 63 EGF receptor 63 Smac mimetics 63 γ secretase 63 mediated apoptosis 63 chemokine receptor 63 drug metabolizing enzymes 63 2 methoxyestradiol 63 activin 63 antisense inhibition 63 p# MAPK 63 redox active 63 GPR# [002] 63 receptor tyrosine kinase inhibitor 63 Angiolix 63 HER2 HER2 63 glutamic acid decarboxylase 63 HIF 1alpha 63 CK2 63 IGF IR 63 aberrantly activated 63 proto oncogene 63 mitogen activated protein kinase 63 MUC1 63 isoenzymes 63 caveolin 63 anti proliferative 63 carcinoembryonic antigen 63 cell adhesion molecule 63 XL# inhibits 63 Raf MEK ERK 63 PARP inhibition 63 cytoprotective 63 splice variants 63 monocytes macrophages 63 demonstrated antitumor activity 63 orally administered inhibitor 63 #HT#A 63 A3 adenosine receptor 63 ADAMTS# 63 ERK1 63 c myc gene 63 poly ADP ribose polymerase 63 GATA3 63 JAK2 kinase 63 vimentin 63 enkephalin 63 leukocyte adhesion 63 V#F mutation 63 MAP kinase 63 VIPR2 63 immunomodulating 63 overactivation 63 tumorigenicity 63 5 HT6 receptor 63 Tissue Factor 63 selective inhibitors 63 Tumor Necrosis Factor 63 IGF 1R 63 HDAC inhibition 63 neuroprotective properties 62 multitargeted 62 histone deacetylases 62 ectopic expression 62 serine threonine 62 immunostimulatory 62 phosphatases 62 antiangiogenesis 62 potently inhibits 62 myelofibrosis polycythemia vera 62 PPARg 62 TGF beta1 62 Wnt beta catenin 62 PTPN# 62 oral JAK1 62 Smad3 62 histone deacetylase HDAC 62 multi kinase inhibitor 62 Tyrima 62 acetylcholine receptor 62 pathological hallmarks 62 CRAC channel 62 VEGF inhibitors 62 oral prodrug 62 c Raf kinase 62 Factor VEGF 62 mGluR5 antagonist 62 chromosomal rearrangement 62 IDH mutations 62 mTOR inhibition 62 retinoic acid receptor 62 HER2 ErbB2 62 Histone 62 #ME# 62 ENaC 62 PDE# 62 antagomirs 62 anaplastic lymphoma kinase ALK 62 AEG# 62 alpha folate receptor 62 selectively inhibited 62 HepG2 cells 62 Sphingomab 62 HSP# inhibitor 62 Akt inhibitor 62 Flt3 62 HuLuc# 62 IGF1R 62 neuroregenerative 62 miR #b [001] 62 vinca alkaloid 62 AT1R 62 IL #p# 62 TMEM#B 62 Bafetinib 62 SERMs 62 D aspartic acid 62 selective antagonist 62 activate SIRT1 62 histone deacetylase 62 ERBB2 62 certain protein tyrosine 62 Upregulation 62 JAK3 62 potent antiproliferative 62 EGFR tyrosine kinase inhibitors 62 HER1 62 splice variant 62 IL 1ß 62 specific lectin receptors 62 antitumor 62 MDR1 62 antisense inhibitor 62 homodimers 62 IGFBP2 62 SIRT2 62 myeloproliferative disorders 62 humanized monoclonal antibodies 62 RNA antagonist 62 telomerase inhibitor 62 EGFR HER2 62 antiproliferative activity 62 CDK4 62 receptor CXCR4 62 Six3 62 metalloprotease 62 related apoptosis inducing 62 LRP5 62 NS#/#A protease 62 PKM2 62 Aplidin 62 transient receptor 62 adrenoceptor 62 ErbB2 positive 62 S#P# 62 IL#R 62 potent inhibitory 62 antisense oligonucleotide 62 HCV protease 62 ERK pathway 62 cytostatic 62 SMAD4 62 glucagon receptor 62 CYP#B# 62 microtubule targeting 62 FGFR1 62 orthotopic model 62 LPS induced 62 Angiotensin converting enzyme 62 N cadherin 62 upregulates 62 ZNF# 62 PML RARA 62 p# activation 62 antimetastatic 62 susceptibility gene 62 molecularly targeted 62 Camptothecin 62 Nod1 62 miR #a [002] 62 selective agonist 62 pharmacokinetic interactions 62 Activating mutations 61 PI3K/mTOR 61 T#I [002] 61 Preclinical studies suggest 61 MEK inhibitors 61 IAP inhibitor 61 calcitonin gene related 61 vascular disrupting 61 C5aR 61 Epothilones 61 AAG geldanamycin analog 61 epithelial tumors 61 HER pathway 61 HER2 overexpression 61 microglial activation 61 renal fibrosis 61 PDE#A 61 cyclins 61 pathogenetic 61 Cdc7 61 P#X# 61 Epstein Barr Virus EBV 61 alpha#beta# 61 nucleoside analogues 61 TNF α 61 geldanamycin 61 p# Shc 61 immunotoxin 61 antiangiogenic agents 61 IgG1 61 MGd 61 TrkA 61 constitutively active 61 protein tyrosine phosphatase 61 kallikrein 61 microRNA miR 61 CYP#A# CYP#D# 61 biologic pathway 61 Interferon gamma 61 potently inhibit 61 #beta HSD1 61 extracellular signal 61 kinase pathway 61 anticancer therapeutics 61 alpha#beta# integrin 61 5 HT4 receptor 61 histone deacetylase inhibitors 61 underlying vasculopathy 61 malignant lymphomas 61 Kinase Inhibitor 61 CD# CD# 61 NS5b 61 galectins 61 depsipeptide 61 interferon IFN 61 Fc fusion protein 61 p#NTR 61 receptor activator 61 PCA3 gene 61 SSc 61 histone deacetylase inhibitor 61 FGFR3 61 reversible inhibitor 61 induce apoptosis 61 adipogenic 61 TNFalpha 61 Hypoxia Inducible Factor 61 pathogenic mechanisms 61 mutational status 61 LRAT 61 cell adhesion molecules 61 5 HT1A 61 IMA# 61 vascular disrupting agents 61 Galectins 61 LymphoStat B belimumab 61 somatostatin receptors 61 thromboxane A2 61 MAbs targeting 61 EGFRvIII 61 RANK ligand 61 glucocorticoid receptor 61 LHRH antagonists 61 potent anticancer 61 Kinases 61 gene rearrangements 61 apoE4 61 gene polymorphisms 61 Cyclin D1 61 ADAM# 61 clusterin 61 Estrogen Receptor 61 tumor antigen 61 immunomodulatory effects 61 IGFBP 3 61 EGFR signaling 61 vinca alkaloids 61 inhibit angiogenesis 61 survivin 61 transgenic mouse models 61 druggable target 61 FGFs 61 MAGE A3 ASCI 61 Akt activation 61 novel VDA molecule 61 prolyl 61 ankyrin repeat 61 IDH1 mutation 61 hypermethylated 61 RhuDex R 61 EphA2 61 focal adhesion kinase FAK 61 CCR9 antagonist 61 Oncogenic 61 sequence homology 61 Myeloid 61 kidney urologic 61 potent antitumor activity 61 small molecule tyrosine 61 GPNMB 61 Histone deacetylase 61 immune modulatory 61 YONDELIS R 61 heparanase 61 HDACs 61 molecular biomarkers 61 FasL 61 HER2 receptor 61 TGF alpha 61 engineered RAP peptides 61 selective kinase inhibitor 61 PGC 1α 61 highly selective inhibitor 61 PTHrP 61 antimitotic 61 OMP #M# 61 NF κB 61 osteopontin 61 PDE# inhibitors 61 effector function 61 Sertoli cell 61 anti fibrotic 61 underlying pathophysiology 61 HDAC inhibitors 61 antisense oligonucleotides 61 AKT inhibitor 61 TAp# 61 humanized monoclonal 61 ErbB2 61 mTOR inhibitors 61 autocrine 61 gastrin 61 somatostatin 61 cardioprotective effects 61 glycosylation profile 61 annexin 61 immune stimulatory 61 cyclin dependent kinases 61 peroxisome proliferator activated 61 4E BP1 61 NKX#.# 61 M2 subunit 61 TLR9 agonists 60 RAF kinase VEGFR 60 Rap1 60 ATG#L# 60 NS4A 60 inverse agonist 60 immuno modulatory 60 potent inhibitor 60 binds selectively 60 thymidylate synthase TS 60 Cathepsin B 60 thrombin receptor 60 MTHFR 60 COX enzymes 60 factor HGF 60 pro angiogenic 60 CDK inhibitor 60 STAT3 signaling 60 lymphoid cells 60 CB2 receptor 60 enzyme inhibitor 60 TNFa 60 immunoregulatory 60 underlying molecular mechanisms 60 SLC#A# [002] 60 SIRT1 activators 60 miR #b [002] 60 aberrant activation 60 neovasculature 60 MCSP respectively 60 apoptotic pathway 60 chemopreventive agent 60 VEGFR1 60 neuroinflammation 60 beta1 integrin 60 TGF β 60 RANK Ligand 60 inhibit EGFR 60 Factor VIIa 60 transmembrane receptor 60 proteoglycan 60 virulence genes 60 lymphocyte activation 60 virulence determinants 60 NMDA N 60 peptide receptor 60 TSH receptor 60 NS5B polymerase 60 PDE4 inhibitor 60 5 HT4 60 PKC inhibitor 60 DNA hypermethylation 60 endophenotypes 60 proapoptotic 60 protein tyrosine kinase 60 PKCi 60 cisplatin resistant 60 ERK signaling 60 upregulating 60 cytotoxin 60 uPAR 60 resolvins 60 dopamine D2 60 heme oxygenase 1 60 oncoprotein 60 oncogenic 60 PI3K AKT 60 cAMP signaling 60 protein tyrosine phosphatases 60 IgG1 antibody 60 CENP E 60 receptor ligand 60 PI3K/Akt pathway inhibitor 60 pyrimidines 60 superoxide dismutase 60 PHD2 60 glutamatergic neurons 60 Hedgehog signaling 60 flavopiridol 60 PPARγ 60 synovial cells 60 alpha synuclein gene 60 cyclic AMP cAMP 60 microRNAs miR 60 gastrointestinal stromal tumors GISTs 60 immunomodulatory 60 novel therapeutic antibodies 60 molecular abnormalities 60 gamma tocotrienol 60 peroxisomal 60 novel immunomodulatory 60 PI3K pathway 60 PI3K inhibitor 60 mitochondrial toxicity 60 mutated p# 60 activated microglia 60 selective modulator 60 Chemokine Receptor 60 HDACi 60 erlotinib Tarceva ® 60 NMDA antagonist 60 IMiDs ® 60 S/GSK# 60 cardiotoxic 60 Pathway Inhibitor 60 β amyloid 60 NFκB 60 neoplastic 60 imexon 60 NS5A 60 STK# [002] 60 novel peptide 60 anti CD3 60 LHRH receptor positive 60 mTOR pathway 60 prodynorphin 60 constitutively activated 60 catenin 60 IL #R 60 FK# 60 Notch receptors 60 receptor subtypes 60 cytokines IL 60 Hsp# inhibition 60 tumor xenograft models 60 p# alpha [001] 60 immunoconjugate 60 GSK3 60 TRAIL Receptor 60 activin receptor type 60 EZH2 60 receptor partial agonist 60 siRNA knockdown 60 lymphangiogenesis 60 intercellular signaling 60 transcriptional regulation 60 genetic loci 60 Thiovir 60 subtype selective 60 amyloidogenic 60 HER2 neu 60 proteasome inhibitor 60 selective agonists 60 Mutational 60 Trp p8 60 HCV replicon 60 hyperphosphorylation 60 vidofludimus 60 CD1d 60 colorectal carcinoma 60 fosbretabulin 60 BCR ABL inhibitors 60 Panzem R NCD 60 LPA1 60 P#X# receptor 60 ARRY # 60 PI3 kinase 60 gemcitabine Gemzar 60 IL 1β 60 SGLT2 60 LRP6 60 GSTP1 60 Gleevec resistant 60 selective orally bioavailable 60 murine models 60 bioactive lipid 60 therapeutic monoclonal antibody 60 N methyl 60 neuropsychiatric diseases 60 TÎ ² 4 60 neurokinin 1 60 TCF#L# 60 papillary renal cell carcinoma 60 Treg cell 60 neuroblastoma tumors 60 Kinase inhibitors 60 suppresses tumor 60 ribonucleotide reductase clinically validated 60 bleomycin 60 GPC5 60 cystic fibrosis transmembrane conductance 60 refractory metastatic 60 RAS RAF MEK 60 hypoxia inducible factor 60 NR2B selective 60 serine threonine kinase 60 antibody mediated 60 peptidic 60 potent cytotoxic 60 prostaglandin D2 60 dasatinib Sprycel 60 mitogen activated protein 60 familial amyloidotic polyneuropathy FAP 60 isotypes 60 epigenetic regulation 60 receptor inhibitor 60 gastric carcinogenesis 60 mouse xenograft models 60 RAS MAPK pathway 60 eNOS 60 #q#.# [002] 60 murine model 60 MMP# 60 SPINK1 60 estrogen receptor beta 60 isoform selective 60 TLR8 60 1α 60 bronchial epithelial cells 60 inhibit metastasis 60 cardio metabolic diseases 59 alkylating 59 EGFR pathway 59 upregulation 59 Monoclonal antibody 59 receptors PPARs 59 nucleolin 59 anticancer activity 59 cellular pathways 59 Macrophage 59 ubiquitin ligase 59 BCL2 59 HCV polymerase inhibitors 59 MEK1 59 constitutively expressed 59 inhibit viral replication 59 tryptase 59 STAT3 59 humanized antibody 59 autophagic 59 HIF 1a 59 ABCB1 59 downregulation 59 receptor antagonism 59 tumor necrosis 59 MAP kinase pathway 59 Sudhir Agrawal D.Phil 59 CagA 59 potent suppressor 59 PDGF receptor 59 nicotinic receptor 59 Voreloxin 59 mGluRs 59 HER3 59 GRNOPC1 contains 59 histone methylation 59 cytokine signaling 59 thetreatment 59 carbohydrate antigens 59 clonogenic 59 orally bioavailable 59 phosphoprotein 59 peptidomimetic 59 DNA adducts 59 OXIGON TM 59 GABAB receptors 59 c KIT 59 Epidermal Growth Factor 59 CD# CEA 59 Aβ 59 neuroinflammatory 59 glycolipids 59 PTP 1B 59 caveolin 1 59 trastuzumab Herceptin ® 59 stem cell pluripotency 59 AGTR1 59 Raf kinase 59 Notch1 59 selectively inhibit 59 cytolytic 59 humanised antibody 59 naturally occurring neuroprotective 59 protein kinases 59 PSMA ADC 59 Fibroblast Growth Factor Receptor 59 multikinase inhibitor 59 Angiotensin II 59 imatinib Gleevec ® 59 pulmonary metastases 59 fusion enhancers 59 MLL2 59 EGFr 59 Enzastaurin 59 investigational humanized monoclonal antibody 59 membrane receptors 59 mimetics 59 taxane derivative 59 hypothalamic pituitary 59 tubulin binding 59 methyl D aspartate 59 skeletal metastases 59 tumor microenvironment 59 anti angiogenic drugs 59 mGluR4 59 sphingolipid 59 sphingosine 1 59 chemokine receptors 59 lysosomal 59 downstream effector 59 activating mutations 59 endothelin receptor 59 DP VPA 59 adrenocortical 59 ER alpha 59 5 HT2B receptor 59 RAF kinase 59 inhibitory effects 59 HBx 59 selective inhibitor 59 5 lipoxygenase 59 NS3 protease 59 hepatoma 59 TTR amyloidosis 59 Htt 59 signal transduction inhibitors 59 oncogenic signaling 59 protein kinase inhibitor 59 siRNA sequences 59 S1P 59 small molecule activators 59 trastuzumab Herceptin R 59 TRAIL receptor antibodies 59 synaptogenesis 59 Akt signaling 59 NF kB pathway 59 gp# protein [002] 59 Cytotoxic T 59 potent inducer 59 Th2 cytokines 59 gene locus 59 siRNAs targeting 59 CCX# 59 prostanoid 59 endogenous ligand 59 apoE 59 EML4 ALK 59 Archexin 59 TGF ß 59 immunomodulation 59 chemokine 59 small molecule modulators 59 PEGylated Fab fragment 59 cathepsin B 59 HER2/neu 59 Fas ligand 59 receptor alpha 59 progressive neurodegenerative disorder 59 Kv#.# 59 anti apoptotic 59 Overexpression 59 proteasome inhibitors 59 Squalamine 59 Endothelin 59 WT1 59 UsiRNAs 59 muscarinic 59 EpCAM 59 oral ghrelin agonist 59 liposomal formulation 59 IRAK1 59 p# inhibitor 59 pRb 59 JAK2 inhibitor 59 histone deacetylase HDAC inhibitor 59 osteoblastic 59 erlotinib Tarceva 59 ErbB3 59 prognostic marker 59 inhibitor COX 59 regulated kinase ERK 59 Granulocyte Colony Stimulating Factor 59 HCV replication 59 trans retinoic acid 59 peptibody 59 GAD# 59 novel anticancer 59 neuro protective 59 Deforolimus 59 sGC 59 tumorigenic 59 immunohistochemical staining 59 melatonin receptor 59 MECP2 gene 59 Selective Inhibitor 59 HDAC 59 prodrugs 59 potently inhibited 59 cyclin dependent kinase CDK 59 molecule epidermal 59 Hsp# inhibitors 59 chimeric monoclonal antibody 59 OXi# 59 MMP9 59 antibody MT# 59 CGEN # 59 lysosomal storage diseases 59 Pten 59 MEK inhibitor 59 tRNA synthetase 59 airway remodeling 59 pegylated liposomal doxorubicin 59 transactivation 59 III EGFRvIII 59 mitogenic 59 molecularly targeted therapies 59 Abeta# 59 casein kinase 59 agonists antagonists 59 prostaglandin synthesis 59 demethylation 59 FTIs 59 serotonin receptor 59 beta subunit 59 peptide antigens 59 superantigens 59 cyclooxygenase 59 Src kinases 59 steroidogenic 59 plasma kallikrein inhibitor 59 CTGF 59 PI3K inhibitors 59 Polymorphisms 59 JAK kinases 59 huntingtin gene 59 miRNA genes 59 osteogenic differentiation 59 DLX5 58 biologic therapeutics 58 Oxidative damage 58 selective serotonin 2C receptor 58 luciferase reporter 58 D aspartate NMDA receptor 58 thrombopoietin 58 phosphoinositide 3 58 Smoothened 58 ActA 58 granzyme B 58 SOD1 gene 58 pancreatic colon 58 secretase 58 lung fibrosis 58 BRAF mutant 58 DNA gyrase 58 novel orally bioavailable 58 germline mutations 58 demyelinating disease 58 AMACR 58 Ras pathway 58 peptide CGRP 58 Wnt pathway 58 LPA1 receptor 58 TRAIL receptors 58 interferon γ 58 RNA silencing 58 Androgen receptor 58 E3 ligase 58 HMG CoA reductase 58 Aurora kinases 58 Reports Preclinical Data 58 melanocyte stimulating hormone 58 Neuroprotection 58 Cytotoxic 58 cyclin D1 58 BAL# [001] 58 NTDDS 58 c myc 58 JAK2 enzyme 58 Monoclonal 58 immunostimulatory effects 58 MKC# MT 58 Onconase 58 Hedgehog pathway 58 extramedullary 58 small molecule inhibitors 58 peptide hormone 58 anti neoplastic 58 NNRs 58 acetylcholinesterase AChE 58 vascular endothelial 58 DNA intercalator 58 Î ² 58 epigenetic mechanisms 58 tRNA synthetases 58 FGFR4 58 Liposomal 58 mevalonate 58 autoantigen 58 uPA 58 Darinaparsin 58 Zalypsis 58 demyelination 58 thalidomide Thalomid 58 neuronal differentiation 58 PEDF 58 posttranslational modification 58 small molecule thrombopoietin 58 heterodimer 58 MCF7 58 orally bioavailable mimics 58 IL8 58 abnormal p# 58 isoprenoid 58 myeloproliferative neoplasms 58 sphingosine kinase 58 HLA DQ2 58 modulatory 58 p# mutations 58 BZL# 58 ß1 58 Id1 58 microglial 58 myo inositol 58 antitumoral 58 noradrenergic 58 RAV# 58 compound AEZS 58 corticosteroid dexamethasone 58 aetiology 58 CD# antigen 58 inducing apoptosis 58 plasma kallikrein 58 Leydig cells 58 SOD1 58 hyperalgesia 58 MAP kinases 58 amyloid beta plaques 58 glial tumors 58 Panzem NCD 58 coagulation cascade 58 Beta catenin pathway 58 immunomodulatory properties 58 tyrosine kinase 58 oncogenic transformation 58 metabotropic glutamate receptors 58 pathophysiologic 58 functional polymorphism 58 inosine 58 Leukemias 58 inducible nitric oxide synthase 58 β1 58 Tumor necrosis factor 58 polyketides 58 vascular disrupting agent 58 renal cell carcinomas