Related by context. Frequent words. (Click for all words.) 63 Sir2 63 SIRT1 63 insulin receptors 62 MAPK 61 Aß 61 Klotho 61 cellular metabolism 61 downregulation 61 mice lacking 60 BACE1 60 superoxide dismutase 60 mitochondrial function 60 MDM2 60 calpain 60 aromatase 60 iNOS 60 overexpressing 60 PGE2 60 p# protein 60 reductase 60 CD8 + 60 mRNA expression 59 monocyte 59 cyclooxygenase 2 59 eNOS 59 Notch signaling 59 Overexpression 59 adipocyte 59 bile acid 59 APOE4 59 NF κB 59 MMPs 59 FGF# 59 Src 59 MeCP2 59 RANKL 59 IL 1beta 59 IFN gamma 59 IGFBP 3 58 p# tumor suppressor 58 CXCL# 58 hyperinsulinemia 58 osteocalcin 58 defensins 58 PPAR gamma 58 Ghrelin 58 proinflammatory cytokines 58 calcineurin 58 hypoxia inducible factor 58 IGF1 58 NMDA receptors 58 EZH2 58 enzymatic activity 58 Caspase 58 Aβ 58 nicotinic receptors 58 glucocorticoid 58 encodes protein 58 Wnt signaling 58 coenzyme 58 Oxidative stress 58 Mcl 1 57 proteolysis 57 leptin hormone 57 RhoA 57 Akt 57 tumor suppressor gene 57 progranulin 57 clusterin 57 galactose 57 FLT3 57 SREBP 57 induced apoptosis 57 telomere shortening 57 dietary restriction 57 protein encoded 57 inflammatory cytokines 57 peripheral tissues 57 PPAR delta 57 NF kappaB 57 nicotinamide 57 signaling molecule 57 Leptin 57 MicroRNA 57 vitamin D receptor 57 Insulin resistance 57 NF1 57 receptor gene 56 XIAP 56 EphA2 56 beta catenin 56 receptor protein 56 STAT3 56 Mice lacking 56 PrP 56 glucose homeostasis 56 protein kinase C 56 GPR# [002] 56 thyroid hormones 56 fatty acid metabolism 56 ubiquitination