Related by context. Frequent words. (Click for all words.) 62 Varki 61 mice lacking 60 cholesterol metabolism 60 Klotho 60 SIRT1 59 neural cells 58 Oxidative stress 58 innate immune 58 Wnt signaling 57 lipid metabolism 57 tumorigenesis 57 mitochondrial function 57 Sir2 57 upregulation 57 mitochondrial dysfunction 57 HHMI investigator 56 NKT cells 56 neuronal cells 56 evolutionarily conserved 56 calpain 56 insulin receptors 56 nicotinamide 56 catalase 56 genetically altered mice 56 superoxide dismutase 56 PNAS paper 56 caloric restriction 56 progranulin 56 dietary restriction 55 #:#-# [035] 55 molecular pathway 55 Nrf2 55 hyperinsulinemia 55 glucose homeostasis 55 Wnt 55 Mozaffarian 55 c Myc 55 glucocorticoid 55 Nedergaard 55 molecular mechanisms underlying 55 MD Ph.D. associate professor 55 NAD + 54 proteolysis 54 neuroprotection 54 Notch signaling 54 NF kB 54 Neu5Gc 54 #:#-# [028] 54 developmental biologist 54 oxidative damage 54 Mayo Clinic neurologist 54 gut microbes 54 Am J Clin 54 synaptic plasticity 54 cell signaling pathways 54 mutant mice 54 Deisseroth 54 induced apoptosis 54 retinal degeneration 54 pathophysiological 54 neurogenesis 54 reactive oxygen species 54 Mitochondrial 54 deficient mice 54 eNOS 54 TGF beta 54 biofilm formation 54 signaling pathway 54 STAT3 54 PrP 54 genomic instability 53 tumor suppressor 53 Caenorhabditis elegans 53 Samuel Lunenfeld Research 53 carcinogenesis 53 myelination 53 proteases 53 Sahlgrenska Academy 53 dysregulated 53 FGF# 53 neuroprotective effects 53 vom Saal 53 Th# cells 53 malignant transformation 53 knockout mice 53 homolog 53 overexpressing 53 stem cell differentiation 53 TLR4 53 protein synthesis 53 Tononi 53 reactive oxygen species ROS 53 spermatogenesis 53 retinoic acid 53 Umea University 53 proinflammatory cytokines 53 osteopontin 53 oxidative stress 53 neuroblastoma cells 53 defensins 53 histone modifications