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(Click for frequent words.) 80 transcriptional activation 79 catenin 77 mitogen activated protein kinase 77 ERK1 2 76 E#F# 76 c MYC 76 Rab5 76 IL 1beta 76 constitutively active 76 proapoptotic 75 Oncogenic 75 c Src 75 deacetylation 75 MAP kinase 75 androgen receptor AR 75 EGF receptor 75 Smad3 75 serine threonine kinase 75 uPAR 74 monocyte 74 IL 1β 74 cytoplasmic domain 74 β catenin 74 constitutively 74 cell adhesion molecule 74 p# MAPK 74 telomerase reverse transcriptase 74 Clusterin 74 RUNX3 74 GLI1 74 LRP6 74 p#Kip# 74 nucleolin 74 autocrine 74 JAK STAT 74 CaM 74 transmembrane protein 74 activin 74 Dystrophin 73 MMP9 73 LNCaP cells 73 CD1d 73 homodimers 73 Fas ligand 73 ß catenin 73 TGF ß 73 caveolin 1 73 TGF alpha 73 proteolysis 73 HIF 1alpha 73 FasL 73 HepG2 cells 73 proteolytic cleavage 73 melanocyte 73 apoptotic pathway 73 SGK1 73 HIF 1a 73 Phosphorylation 73 cathepsin B 73 phosphorylates 73 TGF b 73 CagA 73 vimentin 73 TAp# 73 transactivation 73 paxillin 73 mediated inhibition 73 VE cadherin 73 inducible nitric oxide synthase 73 KLF4 73 astrocytic 72 serine protease 72 prostaglandin E2 PGE2 72 cytochrome c 72 beta subunit 72 tumor suppressor protein 72 FGFR3 72 E3 ligase 72 HOTAIR 72 Macrophage 72 proto oncogene 72 subcellular localization 72 oncoprotein 72 induces apoptosis 72 ERK signaling 72 receptor tyrosine kinase 72 enzymatic activity 72 downregulates 72 transcriptional repressor 72 virulence genes 72 adhesion molecule 72 FKBP# 72 TGF β 72 cyclin E 72 upregulates 72 p#NTR 72 extracellular signal 72 lysosomal 72 EphB4 72 ectopic expression 72 microglial 72 ubiquitylation 72 coexpression 72 thioredoxin 72 iNOS 72 CD#b 72 SIRT2 72 cells transfected 72 cathepsins 72 matrix metalloproteinase 72 autophagic 72 synuclein 72 tyrosine phosphorylation 72 estrogen receptor alpha 72 TRAIL induced apoptosis 72 LDL receptor 72 Histone 72 histone H3 72 EBNA1 72 mitogen activated protein kinases 72 FGFs 72 transgene expression 72 DNMT1 71 Cytotoxic T 71 phosphatidylinositol 3 71 H#K#me# 71 IFN gamma 71 lymphoid cells 71 neurite outgrowth 71 constitutively expressed 71 induced apoptosis 71 MEK1 71 vascular endothelial 71 Hedgehog signaling 71 carcinoembryonic antigen 71 TNFalpha 71 mRNA expression 71 aberrantly activated 71 β1 71 KLF2 71 GSK 3ß 71 ERK1 71 microglial activation 71 STAT1 71 MAPK pathway 71 transduced 71 cytosolic 71 dimeric 71 IFNg 71 ubiquitin ligase 71 interferon γ 71 Sgk1 71 intracellular signaling 71 oncogenic transformation 71 GRP# 71 EGFP 71 c myc 71 morphogen 71 transmembrane receptor 71 EF Tu 71 protein kinase C 71 thyrotropin 71 E3 ubiquitin ligase 71 NFκB 71 hTERT 71 MyD# 71 MT1 MMP 71 transcriptional regulation 71 cyclin B1 71 CD#c 71 hepatoma 71 phosphoprotein 71 CXCL# 71 ENaC 70 MMP# 70 MMP2 70 adrenoceptor 70 Rac1 70 Akt activation 70 phagocytosis 70 homodimer 70 glycosylated 70 TGF beta1 70 thrombospondin 70 OCT4 70 Nedd4 70 regulated kinase ERK 70 GAPDH 70 antiapoptotic 70 phosphate S1P 70 Rb#/p# 70 hypoxia inducible factor 70 substrate specificity 70 IL #R 70 cyclooxygenase COX 70 NF kappaB activation 70 alpha subunit 70 Runx2 70 Overexpression 70 NKG2D 70 hydrolase 70 selectively inhibited 70 Cathepsin B 70 cardiac fibroblasts 70 isoenzyme 70 UCP2 70 Upregulation 70 TGF ß1 70 upregulating 70 cysteine protease 70 Foxp3 70 Vps# 70 Aromatase 70 NKX#.# 70 TNF α 70 selective inhibition 70 oligomerization 70 overexpressing 70 pRb 70 functional polymorphism 70 cadherin 70 proline rich 70 RhoA 70 glioma cells 70 serine threonine 70 VEGF receptor 70 SMN1 70 TGF β1 70 EphA2 70 metalloproteases 70 cAMP signaling 70 protein tyrosine kinase 70 intracellularly 70 Dysregulation 70 JAK2 enzyme 70 fibrogenesis 70 Protein Kinase C 70 aminopeptidase 70 MEFs 70 Epstein Barr Virus EBV 70 mediated apoptosis 70 erythrocytes 70 downregulation 70 cytokine signaling 70 GABAergic interneurons 70 leptin receptor 70 HIF 1α 70 Sp1 70 TXNIP 70 presynaptic 70 VEGF expression 70 IGFBP2 70 sortilin 70 Smoothened 70 P2X 70 Polymorphisms 70 IRE1 70 Leydig cells 70 eIF4E 70 keratinocyte 70 PIP3 70 nucleolar 70 N Myc 70 TNFa 70 chemokine receptor 70 kinase domain 70 protein tyrosine phosphatase 70 GFAP 70 receptor mediated endocytosis 70 tumorigenicity 70 PGC 1α 70 proteoglycan 70 vascular endothelial cells 70 ubiquitination 70 E1A 70 PDGFR 70 Vpr 70 adipogenic 69 RNA polymerases 69 epithelia 69 methyltransferase 69 tropomyosin 69 Huntingtin 69 acyl CoA 69 P selectin 69 LRP5 69 adipogenesis 69 PC# cells 69 glycosyltransferase 69 PKC isoforms 69 miR# 69 acinar 69 IL 1ß 69 thymidylate synthase TS 69 ERalpha 69 phosphorylated 69 kinase pathway 69 lymphoid 69 CEACAM1 69 phospholipase A2 69 phagocyte 69 phosphatase 69 isomerase 69 calpain 69 Dpp 69 Mcl 1 69 PTPN# 69 polyamine 69 neuromuscular junction 69 1alpha 69 plasmacytoid dendritic cells 69 cell adhesion molecules 69 subcellular compartments 69 Cyclin E 69 histone deacetylases 69 Inactivation 69 PAK1 69 Th1 type 69 Tie2 69 Activating mutations 69 metalloprotease 69 cyclin dependent kinase inhibitor 69 amino terminal 69 histone acetylation 69 nAChRs 69 IFN γ 69 Kv#.# 69 SMase 69 TIMP 1 69 pathophysiological effects 69 mRNA translation 69 Caspase 69 glucose transporter 69 dimerization 69 focal adhesion kinase FAK 69 WT1 69 phospholipase 69 AhR 69 TSLP 69 intronic 69 Notch signaling 69 cyclooxygenase 2 69 FGFR4 69 MAPK 69 Transcriptional 69 myofibroblast 69 genes encoding 69 M1 muscarinic 69 Htt 69 phosphoinositide 69 glomerular 69 CCL# 69 intestinal mucosa 69 CCR7 69 TGFß 69 pDC 69 MDM2 69 osteoblast 69 LPS induced 69 receptor signaling 69 synthetase 69 heme oxygenase 1 69 perivascular 69 downregulated 69 NFkappaB 69 TGFβ 69 Src kinase 69 Catenin 69 apoptosis pathways 69 tumor suppressor PTEN 69 Kupffer cells 69 Tissue Factor 69 Corynebacterium 69 ABCB1 69 Src 69 Secretase 69 oncogenic 69 costimulation 69 cyclic AMP cAMP 69 Galectin 69 dephosphorylation 69 COL#A# 69 caspase activation 69 renal fibrosis 69 constitutively activated 69 BMP signaling 69 Protein Kinase 69 survivin 69 hydrolases 69 cofilin 69 guanosine 69 apoE 69 monocyte chemotactic protein 69 mitogenic 69 DLX5 69 replicase 69 innate immune responses 69 cyclins 69 caveolin 69 chromatin structure 69 TIMP 69 splenocytes 69 proximal tubule 69 T lymphocyte 69 nitrotyrosine 69 Integrin 69 V#F mutation 69 cell motility 69 Extracellular 69 secretase 69 Flt3 69 lyase 69 osteogenic differentiation 69 Ca2 + 69 HER2 neu 69 p# activation 69 1α 69 peptidase 69 inverse agonist 69 sphingomyelin 69 Notch receptor 69 EZH2 69 FLT3 69 ER alpha 69 ChR2 69 P cadherin 69 S1P 69 Monocyte 69 p# mitogen activated 69 potent inducer 69 N cadherin 69 STIM1 69 myogenesis 69 C EBP alpha 69 matrix metalloproteinases 69 cystic fibrosis transmembrane conductance 69 FOXO3a 69 effector molecules 69 Nod1 69 epithelial cells lining 69 APOBEC3G 69 glucocorticoid receptor 69 NADPH oxidase 69 epithelial cell 69 carboxyl terminal 68 protein phosphatase 68 dependent protein kinase 68 adipocyte 68 biogenesis 68 miR #a [001] 68 luciferase reporter 68 intercellular adhesion molecule 68 beta1 integrin 68 hypermethylated 68 NF κB 68 1beta 68 ERBB2 68 H#K# [002] 68 inhibitory receptor 68 PrP 68 PKC alpha 68 retinoic acid receptor 68 BMAL1 68 eNOS 68 endocytosis 68 cytoplasmic 68 Skp2 68 apoptotic 68 PPARg 68 anaphase promoting complex 68 oxidase 68 thymidine kinase 68 LKB1 68 Drp1 68 Cyclin D1 68 acetylcholine receptor 68 HDAC2 68 caveolae 68 metabolic enzymes 68 ERK pathway 68 beta amyloid peptide 68 serine proteases 68 SUMOylation 68 Wnt signaling 68 Hypoxia Inducible Factor 68 c Myb 68 isoforms 68 beta actin 68 basolateral 68 Angiotensin converting enzyme 68 mice lacking 68 PI3K Akt 68 posttranslational modifications 68 Akt signaling 68 TLR2 68 histone modifications 68 ciliated 68 5 HT2A serotonin 68 Lyn kinase 68 oligomeric 68 lipoxygenase 68 PTEN protein 68 ubiquitinated 68 plasminogen 68 pDCs 68 Interferon gamma 68 eotaxin 68 BCL#A 68 Cdc7 68 γ secretase 68 extracellular domain 68 enterocytes 68 Rho GTPase 68 RIP1 68 Immunohistochemical analysis 68 hydroxylase 68 PU.1 68 AT1R 68 HER2 receptor 68 tyrosine kinase receptor 68 endonuclease 68 granzyme B 68 podocyte 68 antiproliferative activity 68 ncRNAs 68 splice variants 68 phosphatidylinositol 68 tRNA synthetase 68 metalloproteinase 68 factor HGF 68 TORC2 68 synaptogenesis 68 chemoattractant 68 GSTP1 68 NAD + 68 Wnt beta catenin 68 PB1 F2 68 mononuclear 68 Monocytes 68 acetyl CoA 68 CD# CD# 68 P. gingivalis 68 SOCS3 68 lipopolysaccharide 68 cardiac myocytes 68 secreted protein 68 tumorigenesis 68 CpG island 68 hypermethylation 68 secretory 68 annexin V 68 paracrine 68 regulated kinase 68 RANTES 68 PKM2 68 tumor antigen 68 lymphangiogenesis 68 prostaglandin synthesis 68 HBx 68 sphingolipid 68 cytolytic 68 actinin 68 operon 68 glycolipids 68 4E BP1 68 BMP4 68 ZNF# 68 Mutational 68 TMEM#B 68 actin polymerization 68 cyclin D1 68 ribosomal protein 68 K + ATPase 68 FGFR1 68 neurofilament 68 NKT cell 68 cytoplasmic tail 68 axon guidance 68 ErbB receptors 68 protein encoded 68 immunodominant 68 anti apoptotic 68 Id1 68 ß1 68 evolutionarily conserved 68 effector function 68 cysteine residues 68 acyltransferase 68 beta catenin 68 nNOS 68 SCD1 68 Tubulin 68 histone modification 68 hepatocyte 68 PIP2 68 proinflammatory 68 myofibroblasts 68 FUS1 68 NFAT 68 HSF1 68 secretory pathway 68 colorectal carcinoma 68 endosomal 68 peroxisome 68 IL #p# 68 null mice 68 immunoreactivity 68 Apc 68 TRPV4 68 amyloidogenic 68 calcineurin 68 adenylate cyclase 68 PDGFR alpha 68 p# Shc 68 c MET 68 MyoD 68 vacuolar 68 prodynorphin 68 potent inhibition 68 GNAQ 68 galectins 68 hematopoietic progenitors 68 inflammatory cytokine 68 prostate epithelial cells 68 TGF Beta 68 phospho 68 PAX5 68 epigenetically 68 transgenic rats 68 transcriptional repression 68 STAT3 68 alveolar macrophages 68 F actin 68 GTPase 68 IL6 68 fascin 68 rRNA 68 alveolar epithelial cells 68 TGF beta pathway 68 triggers apoptosis 68 colon carcinoma 68 p# deficient 68 HDAC6 68 E cadherin 68 Hypothalamic 68 S. cerevisiae 67 glucokinase 67 effector cells 67 missense mutation 67 interleukin IL -# 67 NQO1 67 wildtype 67 regulates gene expression 67 cyclin dependent kinase 67 GluR1 67 NF kappaB 67 Smad4 67 MnSOD 67 LDLR 67 tyrosine kinase 67 cofactor 67 ADAMTS# 67 heterodimers 67 BCL2 67 hepatic lipase 67 β actin 67 Jhdm2a 67 HSP# 67 stably expressing 67 nicotinic acetylcholine receptor 67 receptor subtype 67 Î ² 67 urease 67 COX2 67 IRAK1 67 receptor CD# 67 NOD2 67 Cx# [001] 67 cholecystokinin CCK 67 Transgenic Mice 67 cytokine receptor 67 S#A# [002] 67 integrins 67 DNA methyltransferases 67 CDK4 67 missense mutations 67 transferrin receptor 67 selenoproteins 67 CHD5 67 proinflammatory cytokines 67 oxidative phosphorylation 67 osteopontin 67 mitogen 67 anti apoptotic proteins 67 BRAF V#E 67 cellular prion protein 67 endogenous ligand 67 huntingtin 67 aryl hydrocarbon receptor 67 IGF1R 67 metallothionein 67 ERK2 67 homolog 67 TTR gene 67 CYP#B# 67 RNA binding 67 transgenic mice expressing 67 centromeric 67 isotypes 67 gluconeogenesis 67 transiently transfected 67 C5aR 67 Hepatocytes 67 occludin 67 cytokeratin 67 leukocyte adhesion 67 MDR1 67 TNFR 67 membrane proximal 67 Smad7 67 SETDB1 67 Cdc# 67 cell lysates 67 RAS RAF MEK 67 NF KB 67 CD4 + T lymphocytes 67 MAPKs 67 Factor Receptor 67 proteinase 67 perilipin 67 Sertoli cell 67 decarboxylase 67 peroxynitrite 67 TSC1 67 tetramer 67 neuronal dysfunction 67 RRM1 67 thymocyte 67 Nampt 67 Bcl xL 67 G6PD 67 cytosol 67 vesicular stomatitis virus 67 downregulating 67 cytokines IL 67 granzyme 67 fibrillin 1 67 BMP2 67 NFkB 67 synovial cells 67 apo AI 67 lysates 67 mononuclear cells 67 transfected cells 67 CaMKII 67 Microtubule 67 IFN g 67 paralogs 67 hnRNP 67 inflammasome 67 endogenous ligands 67 NMDAR 67 intracellular proteins 67 mesangial 67 SSc 67 Fibroblasts 67 supernatants 67 Rho kinase 67 E cadherin expression 67 effector memory 67 MMP7 67 excitatory neurotransmitter glutamate 67 tyrosine hydroxylase 67 stably transfected 67 RANKL 67 PAR1 67 EGFR receptor 67 mRNA encoding 67 superoxide dismutase 67 hyperactivated 67 haematopoietic 67 raphe 67 anti inflammatory cytokine 67 cellular metabolism 67 dehydrogenases 67 outer membrane proteins 67 ATPase 67 Western blotting 67 prostaglandin E 67 c fos 67 Intracellular 67 plasma membrane 67 untranslated regions 67 mitochondrial respiration 67 Notch1 67 telomere dysfunction 67 CCL5 67 downstream effector 67 colorectal adenocarcinoma 67 adipokines 67 messenger ribonucleic acid 67 muscarinic receptors 67 #BP# 67 CPEB 67 immunoregulatory 67 reductase 67 gene polymorphism 67 EGFRvIII 67 Aß 67 lectins 67 mTOR signaling 67 insulin signaling pathways 67 uracil 67 palmitate 67 RAR beta 67 Integrins 67 overactivation 67 protein secreted 67 cardiolipin 67 steroidogenic 67 Polymorphism 67 Factor VEGF 67 colocalization 67 spermidine 67 transthyretin 67 EGFR protein 67 HEK# cells 67 heterochromatic 67 fibrocytes 67 heterodimer 67 pyrimidines 67 plexiform 67 gene p# 67 pleiotropic 67 Wnts 67 adhesion molecules 67 transgenic mouse models 67 pro inflammatory cytokine 67 malignant phenotype 67 cyclic adenosine monophosphate cAMP 67 gastric mucosa 67 peroxidase 67 ribosomal DNA 67 PLA2 67 phosphorylate 67 GSTT1 67 mucins 67 intestinal epithelial cells 67 β cells 67 Abl 67 microtubule dynamics 67 ribosomal proteins 67 AMPA receptor 67 gene polymorphisms 67 lacZ 67 JNK1 67 tryptase 67 Protein kinase 67 syntaxin 67 somatostatin 67 upregulation 67 VSV G 67 tenascin C 67 Vascular endothelial growth 67 glycolytic 67 VEGFR1 67 antigen receptor 67 osteoclast formation 66 downstream effectors 66 CD8 + 66 H#K# [001] 66 Drosha 66 estrogen receptor beta 66 EGF receptors 66 UCP1 66 NADPH 66 NS5B 66 matrix metalloproteinases MMPs 66 GPR# [002] 66 PDGF receptor 66 IKKß 66 histone methylation 66 erythropoiesis 66 Wnt signaling pathway 66 Th2 cytokines 66 mRNA transcripts 66 ERa 66 adipose cells 66 somatostatin receptors 66 miRNA expression 66 TGF beta signaling 66 triphosphate 66 exocytosis 66 DGAT1 66 PI3K/Akt 66 Lymphocytes 66 methylated DNA 66 immunoblotting 66 prostaglandin E2 66 adaptive immunity 66 Rho GTPases 66 E selectin 66 Arp2 3 66 thyroid hormone receptor 66 peroxisomes 66 transcriptionally active 66 CXCR4 66 monocytic 66 alternatively spliced 66 posttranslational modification 66 ERK phosphorylation 66 Brain derived neurotrophic 66 acetyltransferase 66 TRAIL R2 66 murine model 66 lysine residues 66 multiprotein complex 66 Hh 66 calcium homeostasis 66 adrenocortical 66 chemokine receptors 66 gene encodes 66 Th2 66 ErbB2 66 peroxisomal 66 postsynaptic 66 tau phosphorylation 66 EGFR signaling 66 malignant prostate 66 actin cytoskeleton 66 Sirt1 66 adipocyte differentiation 66 tumor suppressor p# 66 transmembrane 66 HuR 66 proteinases 66 isoenzymes 66 Cadherin 66 diffusible 66 CCR9 66 aldehyde dehydrogenase 66 Neuropeptide Y 66 murine 66 microRNA #a 66 Cytoplasmic 66 mouse embryonic fibroblasts 66 Aβ 66 S. enterica 66 Phenylalanine 66 eicosanoid 66 GATA3 66 mesenchymal cell 66 PEDF 66 pharmacological inhibition 66 sequence homology 66 CD# expression [001] 66 steroidogenesis 66 ErbB4 66 SPINK1 66 proline 66 peptide receptor 66 Eg5 66 regulating gene expression 66 ribonuclease 66 FANCD2 66 DHFR 66 intracellular bacteria 66 Endothelial 66 cholesterol homeostasis 66 PHD2 66 ARF1 66 neuroblastoma cells 66 replicon 66 amyloid ß 66 Mdm2 66 PKD1 66 nitric oxide synthase 66 oncoproteins 66 protein tyrosine phosphatase 1B 66 ouabain 66 DNA demethylation 66 Polycomb 66 p# alpha [001] 66 PECAM 1 66 HER2 HER3 66 transcriptionally 66 BRAF protein 66 genomic instability 66 C. albicans 66 neuropeptide Y NPY 66 monocytes macrophages 66 costimulatory molecules 66 transferase 66 osteoblastic 66 gene rearrangements 66 S6K 66 polycystin 66 CD# expression [002] 66 Nf1