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(Click for frequent words.) 66 potently inhibit 64 tumor subtypes 64 VIPR2 64 gp# protein [002] 63 antimitotic 63 antiapoptotic 63 immune modulating 62 MAPK pathway 62 deacetylation 62 amyloid plaque formation 62 JAK#/JAK# 61 Epothilones 61 vivo potency 61 TNFR 61 HCV protease inhibitors 61 BRAF kinase 61 HuR 61 Anticalins R 61 estrogen receptor alpha 61 antigen adjuvant 61 Hedgehog inhibitor 61 IAP inhibitor 61 humanized monoclonal antibodies 61 melanocortin receptor 60 inverse agonist 60 inhibiting tumor 60 chimeric monoclonal antibody 60 #HT#A 60 LRP5 60 pleiotropic effects 60 metaglidasen 60 M2 subunit 60 HUMIRA resembles 60 potent antiproliferative 60 Protease inhibitors 60 5 HT2A inverse 60 IMiDs ® 60 tubulin inhibitor 60 fusion enhancers 60 immuno modulatory 60 cyclic AMP cAMP 60 Pim kinases 60 immune stimulatory 59 HER2 HER3 59 GnT 4a 59 glucocorticoid receptor 59 PI3K/mTOR 59 prostanoid 59 Smac mimetic 59 antibody mediated 59 humoral immune responses 59 inhibitory neurotransmitters 59 folate metabolism 59 tyrosine phosphorylation 59 drug metabolizing enzymes 59 histone deacetylase HDAC 59 microtubule inhibitor 59 rifamycins 59 IgG antibodies 59 cytoprotective 59 receptor inhibitor 59 MTP inhibitor 59 drug metabolizing enzyme 59 immunotherapeutic approaches 59 FGFs 59 Pathway Inhibitor 59 TXNIP 59 Notch receptors 59 CRAC channel 59 neuroinflammatory 59 reversible inhibitor 59 neuronal dysfunction 59 pre mRNA splicing 59 Anticalins ® 59 phenotypic expression 59 JAK inhibitors 59 MMP9 58 racemic mixture 58 GABA aminotransferase 58 lysophosphatidic acid 58 nanomolar 58 multigenic 58 eTag assays 58 opioid peptides 58 peptidic 58 muscarinic 58 potent suppressor 58 antibody reagents 58 IDH mutations 58 intracellular signal transduction 58 orally bioavailable 58 favorable pharmacokinetic 58 Onconase 58 airway responsiveness 58 MetAP2 58 anticancer therapeutics 58 ligand receptor 58 CoVal TM fusion 58 cytopathic 58 multitargeted 58 immunotoxin 58 Posiphen 58 pathogenic mutations 58 potently inhibits 58 DNA methylation patterns 58 glycolipids 58 serum PTH 58 neuroligins 57 glycogen synthesis 57 anticancer activity 57 glial tumors 57 Darapladib 57 triglyceride lowering 57 Smac mimetics 57 beta adrenergic receptors 57 #T# L1 57 norepinephrine reuptake inhibition 57 noncoding RNA 57 vascular endothelial 57 OMP #M# 57 gene rearrangements 57 potently inhibited 57 murine models 57 Modrenal 57 thymidylate synthase 57 p# activation 57 uroguanylin 57 BRAF V# mutation 57 5 HT2C receptor 57 CC genotype 57 integrin receptors 57 histone modification 57 pan genotypic 57 cell adhesion molecules 57 HCV replication 57 PDGF alpha receptor 57 phosphorylated proteins 57 immune suppressive 57 dihydrofolate reductase 57 rxRNA 57 gene polymorphism 57 polyketides 57 Preclinical studies suggest 57 antiangiogenesis 57 liposomal formulation 57 antitumour 57 Darinaparsin 57 intracellular pathway 57 microRNA molecules 57 fatty acid biosynthesis 57 paxillin 57 thrombopoietin TPO natural 57 NF kB Decoy 57 p# alpha [001] 57 neuroactive 57 proinflammatory mediators 57 nucleoside analogs 57 dopamine transporter DAT 56 act synergistically 56 neuropsychiatric diseases 56 Janus Kinase 56 nanomolar potency 56 epigenetically 56 GABAB receptors 56 NS4B 56 innate immune responses 56 Myolimus 56 proteasome inhibitors 56 warfarin erythromycin 56 cortisol synthesis 56 Squalamine 56 anti amnesic 56 cypin 56 anionic backbone 56 metabolite concentrations 56 p#/CBP 56 benzimidazole 56 suppresses tumor 56 acetylcholinesterase 56 mecamylamine 56 biogenic amine 56 cytostatic 56 coactivators 56 novel anticancer 56 antagomirs 56 prescribed proton pump 56 synthetic siRNA 56 KCNH2 56 calcitonin gene related 56 Rho GTPases 56 GRP# 56 CCR9 antagonist 56 antitumor effects 56 pharmacodynamic markers 56 lenalidomide dexamethasone 56 PI3K/Akt pathway inhibitor 56 Dyax phage display 56 SGLT Inhibitors 56 M. pneumoniae 56 chromatin structure 56 RAF kinase 56 REGN# 56 humoral responses 56 proliferation apoptosis 56 beta HSD1 56 novel orally bioavailable 56 osteosarcomas 56 butyrylcholinesterase 56 cholesterol homeostasis 56 retinoid X 56 Wnts 56 RGB # 56 protein kinase inhibitor 56 neuropilin 56 oral immunomodulatory 56 multiprotein complex 56 apoptosis proteins 56 MAP kinases 56 adhesion proteins 56 macrophage inflammatory 55 RNA antagonists 55 DNA gyrase 55 Apo2L 55 beta amyloid peptide 55 mitogen activated protein kinases 55 telomerase inhibitor 55 immune modulatory 55 amyloid formation 55 aurora kinase 55 OXIGON TM 55 fast skeletal troponin 55 activate SIRT1 55 alpha TNF α 55 nanomolar concentrations 55 hypericin 55 GSTM1 gene 55 DNA demethylation 55 cyclic adenosine monophosphate cAMP 55 CD8 T cell 55 TRIOLEX HE# APOPTONE HE# 55 synovial fibroblasts 55 transcriptional regulators 55 biomarker identification 55 mitochondrial metabolism 55 telomerase activator 55 prognostic biomarker 55 potent anticancer 55 toxic amyloid beta 55 Nanobodies TM 55 ADME properties 55 Rigel R# 55 ENPP1 55 adrenal hormones 55 synaptic transmission 55 glutamate signaling 55 auristatin 55 cellular uptake 55 histone modifications 55 resolvin 55 Archexin 55 genotype phenotype 55 Alternative splicing 55 insulin sensitizing 55 enzyme inhibitor 55 tubulin binding 55 gastrin 55 AKT pathway 55 IMiDs R 55 VDAs 55 IMiDs 55 adenosine 5' triphosphate ATP 55 electrophysiological recordings 55 TNF alpha antagonist 55 SGS# 55 sirtuin enzymes 55 siRNA sequences 55 TMPRSS2 ERG fusion 55 small molecule Hedgehog 55 5 HT4 55 immunological responses 55 rhIGFBP 3 55 protein synthesis inhibitors 55 subtype selective 55 AAV vector 55 autocrine 55 proteasome inhibitor 55 XL# XL# XL# XL# 55 dose proportionality 55 receiving immunosuppressive therapy 55 cellular pathways 55 methylation patterns 55 androgen signaling 55 underlying pathophysiology 55 proteinase 55 systemically administered 55 somatostatin receptor 55 Caspases 55 DXL# 55 receiving TNF blockers 55 CDKs 55 enzymatic pathways 55 sirtuin activators 55 CINOD 55 pyrimidines 55 prodynorphin 55 mechanistic insights 54 sulphoraphane 54 anti angiogenic agent 54 chloride channels 54 CCR5 co 54 nicotinic 54 protein conformation 54 Valproic acid 54 ActA 54 serotonin transporters 54 cyclic guanosine monophosphate 54 OnDose TM 54 vitro antiviral 54 DPP4 54 intracellular signaling 54 R#/MEM # 54 carbohydrate polymer 54 antimetastatic 54 lipidoid 54 biologic pathways 54 integrase enzyme 54 genomic variants 54 electrophysiological properties 54 hormone secretion 54 AKT inhibitor 54 glycan binding 54 antitumoral 54 Tyrima 54 PI3K inhibition 54 Genetic mutations 54 tau phosphorylation 54 Stress hormones 54 novel immunomodulatory 54 corticosteroid dexamethasone 54 Pterostilbene 54 Cathepsin S 54 genes predisposing 54 PI3K inhibitor 54 PI3 K 54 cyclophilin inhibitors 54 siRNA therapeutic 54 lipopeptide 54 gene expression patterns 54 PSMA ADC 54 mitochondrial fusion 54 IAP inhibitors 54 selectively inhibits 54 pulse amplitude 54 chemically modified siRNA 54 ErbB receptors 54 Bruton tyrosine kinase Btk 54 phage display libraries 54 factor TNF 54 radioprotective 54 kinesin motor 54 GABAA 54 pan HDAC inhibitor 54 chromatin remodeling 54 cytidine nucleoside analog 54 AKT1 mutation 54 PEGPH# 54 neurotransmitter receptors 54 signal transduction inhibitor 54 radiolabeled monoclonal antibody 54 signaling cascades 54 H#N# mAbs 54 CDDO Im 54 CYP#E# 54 extracellular dopamine 54 synthases 54 neurotransmitter receptor 54 oncogenic signaling 54 RTP #i 54 NF kB signaling 54 HIV protease 54 investigational therapies 54 synaptogenesis 54 Curaxin 54 endogenous ligand 54 histone deacetylases HDAC 53 synthetic siRNAs 53 genomic alterations 53 cellular prion protein 53 SAPAP3 53 insulin signaling pathway 53 hydrolytic 53 include ketoconazole acetaminophen 53 cortical excitability 53 LY# [003] 53 High Impact AMPAKINE 53 tRNA synthetases 53 Pimavanserin 53 inhaled TPI ASM8 53 LJ# [002] 53 Gag polymorphisms 53 Nod1 53 macrocyclic lactone 53 intestinal microflora 53 HQK 53 overactivated 53 intracellular compartments 53 alpha glucosidase 53 NS#/#A protease 53 selective adenosine 53 Spiegelmer 53 detoxify harmful 53 AMPK activators 53 partial agonists 53 TG# [003] 53 GABA receptors 53 APOE genotype 53 clefting 53 allosteric mechanism 53 glycogen metabolism 53 GABAA receptors 53 druggable target 53 Anticalins 53 radiolabeled 53 morpholino 53 stimulate neurogenesis 53 potent topoisomerase II 53 ATL# [001] 53 liposome formulation 53 BNC# 53 calcineurin 53 cell signaling pathways 53 mechanistic studies 53 Anticalin 53 AtuRNAi 53 POMC gene 53 genes encode proteins 53 CD# expressing 53 intracellular proteins 53 alpha 2A adrenergic 53 Chronic ITP 53 glyco 53 siRNA therapeutics 53 Oncotype 53 TRPV1 agonist 53 receptor activation 53 paclitaxel Taxol ® 53 synapse formation 53 enzymatic reactions 53 STAT3 activation 53 ATG#L# 53 psoriatic skin 53 Diels Alder reaction 53 REMINYL ® 53 potent activator 53 immunodeficient 53 inhibits tumor 53 GPR# agonist 52 anti resorptive 52 KSP inhibitor 52 glycosylation pattern 52 Misfolded proteins 52 Posiphen TM 52 HIF PHIs 52 adult neurogenesis 52 LXRs 52 cAMP signaling 52 ANAVEX #-# [002] 52 colorectal carcinogenesis 52 mutated EGFR 52 vitellogenin 52 XmAb# 52 engineered proteases 52 post translational modifications 52 antiplatelet medications 52 PKMzeta 52 EHT AGN 52 protein kinase inhibitors 52 CTA# 52 radiosensitive 52 biochemical abnormalities 52 Camptothecin 52 epigenetic regulation 52 fucoxanthin 52 bacterial enzyme 52 NPM1 gene 52 tarantula venom 52 MEK inhibitor 52 vascular disrupting 52 platelet adhesion 52 VA# [002] 52 PDZ domains 52 nitric oxide donating 52 protein tyrosine kinases 52 previously uncharacterized 52 N chlorinated antimicrobial 52 phosphorylated Akt 52 gamma synuclein 52 aptamer therapeutics 52 HMG CoA reductase inhibitory 52 molecularly defined 52 PARP inhibitor 52 Aganocide 52 Davanat 52 c myc gene 52 chromosome rearrangements 52 calcium calmodulin 52 physicochemical properties 52 2 methoxyestradiol #ME# 52 resorptive 52 modulate sirtuins 52 pharmacodynamic parameters 52 indibulin 52 glucagon secretion 52 GSOs 52 triterpenoids 52 hippocampal neurogenesis 52 #q# deletion 52 RAS blockers 52 tRNA synthetase 52 2DG 52 inhibit platelet function 52 RDEA# potent 52 RNA polymerases 52 blood clot dissolving 52 potency dosing 52 neurotransmitter GABA 52 pro apoptotic proteins 52 neural substrates 52 fusogen 52 endpoint assays 52 heavily pretreated 52 sodium stibogluconate 52 neurohormonal 52 reproducible quantitative multiplexed 52 conformational changes 52 drugable 52 Alu elements 52 novel chimeric natriuretic 52 DPOLT 52 neuronal plasticity 52 CRF1 receptor antagonist 52 radiolabeled antibodies 52 amyloid beta plaques 52 PU H# 52 EZN 51 α synuclein 51 Rh proteins 51 epothilones 51 locomotor activity 51 brivanib 51 anti cyclic citrullinated 51 endogenous cannabinoids 51 prognostically 51 mechanistic insight 51 nanomedicines 51 Purine 51 inhibitory transmitter 51 dopamine synthesis 51 medically inoperable 51 huN# DM1 51 imexon 51 ribosomal genes 51 membrane fusion 51 ApoA l 51 antisense molecules 51 intercellular communication 51 Stat5 51 PKC# 51 effector molecules 51 Lisofylline LSF 51 cyclic peptide 51 potent recombinant 51 RNA sequences 51 metabolomic 51 proteomes 51 Th2 immune 51 AQD class 51 clonal expansion 51 poloxamer 51 hormonal milieu 51 apoptosis inducer 51 PML RARA 51 chemical reactivity 51 Severe hypersensitivity reactions 51 Sgk1 51 PSN# [002] 51 aurora kinase inhibitor 51 DXL TM antibodies 51 PTK# 51 JAK STAT 51 acting inhaled anticholinergic 51 Membrane proteins 51 TIR1 51 leptin resistant 51 PKC enzyme 51 PEG SN# 51 paralogs 51 intra tumoral 51 exosome 51 nanoparticle formulations 51 alkylating agent 51 pegylated recombinant 51 tipifarnib 51 behavioral neurobiology 51 histone H4 51 TRPV1 receptor 51 lipid rafts 51 neuronal signaling 51 EBV infection 51 kynurenic acid 51 agonist compounds 51 K ras mutation 51 PV module efficiencies 51 PEGylated 51 phenotypic traits 51 synaptic function 51 Quorum sensing 51 phylogenetic analyzes 51 Apoptone HE# 51 bilaterians 51 L Annamycin 51 naringenin 51 inflammasome 50 PRLX # 50 enzymatic activity 50 translationally 50 huC# DM4 50 pentamidine 50 basal cell carcinoma squamous 50 novel topoisomerase 50 metazoan 50 commensal bacteria 50 salinomycin 50 enzyme catalysis 50 solubilization 50 purified inactivated vaccine 50 lipid particle 50 myosins 50 amygdala reactivity 50 prostratin 50 equimolar 50 RecA 50 Pancreate 50 carbonyls 50 Mipomersen 50 talabostat 50 TGFb 50 meiotic recombination 50 containing bioactive nutrients 50 SAR# [002] 50 include VALSTAR TM 50 kinase domain 50 Vps# 50 Genasense ® oblimersen 50 amygdala neurons 50 oral Factor Xa 50 OpenArray TM 50 polyethylene glycol PEG 50 nicotinic acetylcholine receptors 50 heritable diseases 50 beta lactam 50 Hsp# inhibitor 50 neurexins 50 antifungal compounds 50 GnRH neurons 50 L Ergothioneine 50 mertansine 50 Zysolin TM 50 neuronal synapses 50 chiral compounds 50 CRACM 50 Litx 50 fatty acid metabolism 50 Cand5 50 cytoskeletal structure 50 COX Inhibiting Nitric Oxide 50 viremic 50 Mycobacterium tuberculosis M.tb 50 conjugates 50 JAK inhibitor 50 SPP# Rasilez 50 chemically alters 50 vismodegib 50 phenotypic differences 50 inflammation thrombosis oncology 50 concurrent ITP 50 oral anticancer 50 ε4 50 ATL# [002] 50 enzymatic digestion 50 biomolecular interactions 50 small molecule defensin 50 mammary epithelial cells 50 Cipralex ® 50 sulfonylhydrazine class 50 topoisomerase II 50 adrenoceptor agonist 50 stem cell mobilizer 50 TRP channels 50 triptolide 50 Preimplantation Factor 50 polymer conjugate 50 novel orally administered 50 adrenergic regulation 50 administered concomitantly 50 antineoplastic 50 tubulin inhibitors 50 chemotherapeutic agent 50 anticoagulant reversing agent 49 LT NS# 49 salivary amylase 49 commercialize lorcaserin 49 apical membrane 49 cephalosporin antibiotics 49 genetically encoded 49 potent antibacterial 49 small molecule 49 CSF Tf 49 immunological mechanisms 49 Monoclonal antibodies 49 rhIGF-I/rhIGFBP-3 49 bioactive molecules 49 metalloenzymes 49 ABL kinase 49 genetic makeups 49 Chemokines 49 oral gallium 49 untranslated regions 49 Kevetrin ™ 49 novel prodrug 49 BioSilicon ™ 49 hereditary antithrombin deficiency 49 intracellular signaling cascades 49 antidiabetic 49 Erimos 49 becoming growingly numb 49 Hox proteins 49 selective kinase inhibitors 49 Rho proteins 49 amyloid imaging 49 mean ± SEM 49 oral isotype selective HDAC 49 pharmacologic treatments 49 mesolimbic 49 BioSilicon 49 angiotensin II receptors 49 #S subunit 49 Metallophile ™ Technology 49 Miraxion Amarin lead 49 oral antiviral 49 orthologous genes 49 physiologic responses 49 novel antiviral therapeutics 49 I3C 49 Transdrug R 49 MALAT1 49 TOCOSOL 49 statin HMG CoA reductase 49 hippocampal neurons 49 botulinum neurotoxins 49 KB# [002] 49 epigenetic changes 49 oral ferric iron 49 potent analgesic 49 immune effector cells 49 Amyloid Precursor Protein 49 SRT# [002] 49 necrotic core 49 Sutent sunitinib 49 CGH microarrays 49 antifolate 49 functional annotation 49 Myocardial Perfusion Imaging 49 MET inhibitor 49 hippocampal function 49 phenotypes 49 PER2 49 cytotoxics 49 fostamatinib disodium 49 defensins 49 glycoside 49 cryptochromes 49 synapse maturation 49 anticancer compound 49 receptor tyrosine kinases RTKs 49 melanocortin receptor agonists 49 silicon carbide SiC gallium 49 Herceptin monoclonal antibody 49 Molnar Szakacs 49 humoral immune response 49 immunological synapse 49 Parkinsonian 49 TSQ Vantage 49 psychopharmacologic 49 prokinetic 49 macrolide antibiotic 49 clioquinol 49 Posiphen ® 49 anti tubercular 49 prostone 49 renin inhibitor 49 potentiating 49 oral isoform selective HDAC 49 remains mystery Yairi 49 Novasome R 48 Arabidopsis genes 48 plus prednisone prednisolone 48 membrane lipids 48 lipid nanoparticle LNP 48 chromosome translocations 48 ELND# 48 homochirality 48 enzymatic pathway 48 NFTs 48 neuroprotectant 48 carbohydrate intolerance 48 mammalian neurons 48 EGFR signaling pathway 48 Eukaryotes 48 DexaSite 48 OPRM1 48 quinoline 48 biosynthetic enzymes 48 RSD# selectively blocks 48 systemic antifungal 48 beta defensins 48 causal pathways 48 perirhinal cortex 48 refractory Hodgkin 48 piperine 48 species ROS 48 heterogeneous catalysts 48 sildenafil citrate Viagra 48 Nonalcoholic fatty liver 48 gyri 48 treat iron deficiency 48 reactivity 48 equipotent 48 mimetic compounds 48 cellular organelles 48 chemotherapeutic drug 48 catalytically active 48 penile erection 48 Aganocide TM 48 novel DACH platinum 48 MultiStat 48 parahippocampal 48 oral hypoglycemic agent 48 Btk inhibitor 48 Junovan TM 48 photoactivated 48 sodium selenite 48 human rhinovirus HRV 48 Additionally MorphoSys 48 Stapled Peptide 48 HuMax Inflam 48 cells osteoblasts 48 Aganocide ® 48 MitoQ 48 epigenetic inheritance 48 using ImmunoGen TAP 48 abdominal subcutaneous fat 48 multiple sclerosis HIV integrase 48 Condroitin sulfate 48 fluorescent nanocrystals 48 myogenic cell 48 PF # [002] 48 Pharmos proprietary 48 patterning technique 48 Dictyostelium 48 fungal infections Hepatitis C 48 adipiplon 48 immunotherapeutic 48 cMET inhibitor 48 influenza neuraminidase 48 negative affectivity 48 nevirapine regimen 47 intestinal microbiota 47 biotransformation 47 metal cations 47 RiVax 47 psoriatic lesions 47 endocasts 47 toxicogenomic 47 novel antifolate 47 fission yeast 47 mu opioid agonists 47 Reactive oxygen species 47 imaging mass spectrometry 47 Formic acid 47 resveratrol quercetin 47 evolvability 47 cytosine methylation 47 PrevOnco ™ 47 peptoids 47 ShearWave Elastography 47 Etoposide 47 glucose intolerant 47 #F AV 47 cardiovascular disease osteoporosis 47 nanocarriers 47 development peramivir neuraminidase 47 sufficient quantities Phe 47 promising anticancer 47 postsynaptic neuron 47 #BP# 47 distantly related species 47 progressive PsA 47 epigallocatechin gallate EGCG 47 neuronal pathways 47 Dr. Leissring 47 correlate genetic variation 47 Biomerk Tumorgrafts 47 defensin mimetic antibiotic 47 gut microbiota 47 pharmacologically active 47 cleavable 47 biophysical characterization 47 enterotypes 47 use transdermal sumatriptan 47 microtissues 47 zebrafish larvae 47 Serum calcium 47 Personalised medicine 47 Bevasiranib 47 cadherins 47 stapled peptides 47 airway anatomy 47 genetic susceptibilities 47 CD4 receptor 47 AMPAKINE R 47 TNFR Fc 47 Clioquinol 47 serotonergic agents 47 gamma oscillations 47 dynamical processes 47 membrane transporters 47 Raman spectra 47 lipid molecules 47 protein filaments 47 circulating angiogenic 47 macrocycles 47 antiarrhythmic medications 47 bicyclic 47 Dense smoke billowed 47 AMP kinase 47 biological molecules 47 hypoxia selective 47 functionalised 47 systemic immunosuppressive 47 cordycepin 47 NITD# 47 intergenic 47 clinical efficacies 47 GSK# [002] 47 fluorescent pigments 47 BRIT1 47 cyclodextrins 47 cellular signaling pathways 47 metalloproteins 47 trastuzumab DM1 T DM1 46 particle morphology 46 habenula 46 gallium containing 46 lateral orbitofrontal cortex 46 PEPCK C 46 desmosomes 46 zotarolimus 46 www.soliris.net 46 underlying molecular mechanisms 46 synergistic combinations 46 apigenin 46 Sexual arousal 46 Atryn 46 Acura Buick Cadillac 46 Thermus thermophilus 46 either Celebrex naproxen 46 camptothecin 46 inherit predisposition 46 Prodrug 46 industrially relevant 46 rifamycin 46 infant formula contaminant 46 midstage trials 46 rolapitant 46 optimized siRNA 46 discodermolide 46 targets N cadherin 46 mitochondrial pathway 46 vincristine sulfate 46 homologies 46 Linaclotide 46 intestinal microbial 46 selective muscarinic 46 pan BCR ABL 46 epigallocatechin gallate 46 Particle acceleration 46 PD2i ® algorithm 46 potent topically