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(Click for frequent words.) 79 Notch signaling 78 neurite outgrowth 78 autophagic 77 ERK signaling 77 TGF ß 77 ERK1 2 77 catenin 77 mitogen activated protein kinase 77 MAPK pathway 76 renal fibrosis 76 caveolin 1 76 TGF b 76 melanocyte 75 tyrosine phosphorylation 75 MAP kinase 75 Rab5 75 caveolin 75 Hedgehog signaling 75 p# MAPK 75 TGF β 75 regulated kinase ERK 75 E#F# 75 Rap1 75 tumor suppressor protein 75 Wnt signaling 74 neuronal differentiation 74 pRb 74 proteolysis 74 p#Kip# 74 Pten 74 autocrine 74 GRP# 74 tumorigenesis 74 proto oncogene 74 receptor tyrosine kinase 74 ectopic expression 74 androgen receptor AR 74 c MYC 74 TGF beta1 74 IL 1beta 74 β catenin 74 phosphorylates 74 protein kinase C 74 proapoptotic 74 VE cadherin 74 Notch1 74 activin 74 TNFalpha 73 TGF ß1 73 metabolic enzymes 73 synaptogenesis 73 STAT3 73 NFAT 73 IL 1β 73 Nod1 73 c Myc 73 NF κB 73 podocyte 73 NFκB 73 calcineurin 73 estrogen receptor alpha 73 Fas ligand 73 cAMP signaling 73 eNOS 73 serine protease 73 microglial 73 HIF 1a 73 oncogenesis 73 serine threonine kinase 73 PGE2 73 ubiquitylation 73 ß catenin 73 IGFBP2 73 p# activation 73 NKG2D 73 Wnt signaling pathway 73 CaM kinase II 73 LKB1 73 FUS1 73 SGK1 73 FGFs 73 oncoprotein 72 HBx 72 SMAD4 72 uPAR 72 STAT3 signaling 72 Foxp3 72 RUNX3 72 SH2 B 72 extracellular signal 72 C EBP alpha 72 STAT1 72 cyclin D1 72 XBP1 72 iNOS 72 cytochrome c 72 TSLP 72 epithelia 72 neurofibromin 72 vimentin 72 JAK2 enzyme 72 downregulation 72 PDGFR 72 cell motility 72 inducible nitric oxide synthase 72 c myc 72 cytokine signaling 72 RhoA 72 LRP5 72 histone deacetylases 72 transcriptional activation 72 constitutively active 72 Nedd4 72 LIS1 72 upregulates 72 HIF 1alpha 72 hyperactivated 72 thioredoxin 72 Clusterin 72 TAp# 72 mediated inhibition 72 PPARγ 72 GATA3 72 cell adhesion molecules 72 IL #R 72 intestinal epithelium 72 HSF1 72 Wnts 72 CD1d 72 FGFR3 72 NFkB 72 Six3 72 phosphatidylinositol 3 72 transmembrane receptor 72 cell adhesion molecule 71 Src 71 E cadherin 71 intracellular signaling 71 transcriptional repressor 71 TNF α 71 UCP2 71 signaling pathway 71 IFN γ 71 epigenetic silencing 71 synapse formation 71 Akt1 71 Smad4 71 paracrine 71 enzymatic activity 71 CEACAM1 71 Cyclin D1 71 Smad7 71 hyperactivation 71 apoE 71 prostaglandin synthesis 71 axon guidance 71 DNMT1 71 evolutionarily conserved 71 ABCA1 71 adhesion molecule 71 transcriptional regulation 71 NF kB pathway 71 tumor suppressor gene 71 EGFR signaling 71 HOTAIR 71 HDAC2 71 deacetylation 71 heme oxygenase 1 71 myofibroblasts 71 Phosphorylation 71 Hh pathway 71 proteoglycan 71 RANKL 71 cytoplasmic domain 71 haematopoietic 71 podocytes 71 adipocyte 71 NFkappaB 71 cystic fibrosis transmembrane conductance 71 hepatocyte 71 COX2 71 Bcl xL 71 S#A# [002] 71 ERK2 71 TGF alpha 71 Lyn kinase 71 TGFβ 71 mesenchymal cell 71 transactivation 71 JNK1 71 Wnt beta catenin 71 LRP6 71 genomic instability 71 FGF# 71 lysosomal 71 microglial activation 71 Vpr 71 MAPK 71 DISC1 71 tumor suppressive 71 MT1 MMP 71 induced apoptosis 71 antiapoptotic 71 BMP signaling 71 HIF 1α 70 overactivation 70 upregulating 70 neural crest 70 VEGF receptor 70 retinoic acid receptor 70 neuromuscular junction 70 Cathepsin B 70 cathepsins 70 ACh 70 activating mutations 70 PGC 1α 70 IRAK1 70 proinflammatory cytokines 70 TGFß 70 demethylation 70 carbohydrate metabolism 70 mTORC1 70 airway remodeling 70 calpain 70 astrocytic 70 PTEN protein 70 NKT cells 70 neuronal dysfunction 70 TGF beta 70 upregulation 70 Akt 70 MAPKs 70 IFN gamma 70 glucocorticoid receptor 70 Fc receptor 70 Prox1 70 FOXP3 70 chromosome condensation 70 PC# cells 70 myeloid cells 70 selective inhibition 70 acinar 70 mitogenic 70 E1A 70 FoxO1 70 KLF# 70 Mcl 1 70 mRNA decay 70 4E BP1 70 p#NTR 70 beta1 integrin 70 protein tyrosine phosphatase 70 Activating mutations 70 lymphangiogenesis 70 epigenetic mechanisms 70 cyclic AMP 70 GABAergic neurons 70 MMP9 70 PEDF 70 ER alpha 70 constitutively expressed 70 mitogen activated protein kinases 70 signaling cascades 70 NOD2 70 nitric oxide synthase 70 cyclins 70 TrkB 70 receptor gamma 70 CTGF 70 TNFa 70 E cadherin expression 70 LDL receptor 70 HepG2 cells 70 NF kappaB activation 70 PTEN gene 70 MMP# 70 BMP4 70 E3 ligase 70 Wnt pathway 70 tropomyosin 70 leukocyte recruitment 70 histone modifications 70 TGF beta pathway 70 cyclooxygenase 2 70 sortilin 70 tyrosine kinase 70 genotoxic stress 70 TGF β1 70 tumor metastasis 70 epigenetic modifications 70 fatty acid oxidation 70 hematopoiesis 70 FKBP# 70 oncogenic 70 MDM2 70 ADAMTS# 70 histone acetylation 70 Sgk1 70 ADAM# 70 ERK pathway 70 Akt activation 70 cellular pathways 70 TGFb 70 IKK beta 70 exocrine 70 homodimers 70 thymidylate synthase TS 70 cell adhesion 70 PrP 70 Aβ 70 WT1 70 vascular endothelial 70 Wnt 70 c MET 70 N Myc 70 Treg cells 70 S1P 70 phosphatases 70 NKX#.# 70 γ secretase 70 cyclophilin D 70 Smurf1 70 PP2A 70 metalloproteinase 70 granzyme B 70 actin cytoskeleton 70 CHD5 70 mitogen activated protein 70 lung epithelium 70 micro RNAs 70 BMAL1 69 NKT cell 69 GLI1 69 paxillin 69 clusterin 69 TRAIL induced apoptosis 69 FGF2 69 fibrogenesis 69 IKK2 69 Ras pathway 69 cytosolic 69 transmembrane protein 69 oligomerization 69 vascular endothelial cells 69 plasminogen 69 CXCL# 69 Jhdm2a 69 Vascular endothelial growth 69 MAP kinase pathway 69 EGF receptor 69 tyrosine kinase receptor 69 dephosphorylation 69 IRE1 69 FOXO3a 69 C1q 69 lymphoid cells 69 p# pathway 69 c Src 69 KCNE2 69 constitutively 69 kinase pathway 69 inflammasome 69 cardiac fibroblasts 69 Dysregulation 69 NF kB 69 epithelial mesenchymal transition 69 GAPDH 69 protein p# 69 GABAergic interneurons 69 SOCS3 69 transthyretin 69 pro angiogenic 69 myogenesis 69 Aromatase 69 osteoblast 69 beta subunit 69 PTPN# 69 inflammatory cytokine 69 ubiquitin ligase 69 mesenchymal transition 69 Htt 69 virulence genes 69 integrins 69 PPARg 69 nNOS 69 Oncogenic 69 leptin signaling 69 tumor angiogenesis 69 p#INK#a 69 beta catenin 69 matrix metalloproteinases 69 gluconeogenesis 69 metalloprotease 69 sphingolipid 69 lymphocyte activation 69 RAS RAF MEK 69 DNA methylation patterns 69 alveolar macrophages 69 Src kinase 69 TET2 69 DLC1 69 TGF beta signaling 69 monocyte 69 KLF4 69 lymphoid 69 innate immune responses 69 Treg cell 69 FOXO1 69 ligases 69 factor HGF 69 Rac1 69 protein tyrosine kinase 69 cytokine 69 cAMP 69 FGFR1 69 Nurr1 69 humoral immunity 69 costimulatory 69 JAK STAT signaling 69 isoenzymes 69 circadian genes 69 eotaxin 69 regulates gene expression 69 AhR 69 hypoxia inducible factor 69 IL 1ß 69 POMC neurons 69 cellular metabolism 69 SIRT3 69 RANK ligand 69 NF kappaB 69 cardiac myocytes 69 MAP kinases 69 Dpp 69 oncogenic transformation 69 ERa 69 anti apoptotic 69 TORC2 69 TXNIP 69 EZH2 69 telomere maintenance 69 Sp1 69 keratinocyte 69 GSK 3ß 69 gene polymorphisms 69 SIRT2 69 cofactor 69 BCL#A 69 mRNA expression 69 epigenetic alterations 69 MLL gene 69 ubiquitination 69 GABAA receptors 69 muscarinic receptors 69 Cdc# 69 glucose transporter 69 telomerase reverse transcriptase 69 apoptotic pathway 69 Wnt1 69 Oxidative stress 69 V#F mutation 69 osteogenic differentiation 69 OCT4 69 N cadherin 69 FGFR2 69 lung fibrosis 69 beta amyloid peptide 69 hypermethylation 69 HDACs 69 PGC1 69 neuroinflammation 69 neuronal cell 69 homolog 69 occludin 69 beta globin gene 69 epithelial cells lining 69 PDGFR alpha 69 acinar cells 69 CPEB 69 Flt3 69 misregulation 69 cadherin 69 CCL# 69 NR#A# 69 FLT3 69 STIM1 68 mitogen 68 regulating gene expression 68 JAK STAT 68 Smoothened 68 AT1R 68 anti inflammatory cytokine 68 PKC alpha 68 DGAT1 68 endoplasmic reticulum stress 68 amyloid β 68 glycolipids 68 vacuolar 68 SUMOylation 68 hepatocyte growth 68 induces apoptosis 68 telomere dysfunction 68 transgene expression 68 Aß 68 polycystin 68 hedgehog signaling 68 CCR7 68 primary cilia 68 pDCs 68 posttranslational modification 68 signal transduction pathways 68 68 epigenetically 68 secretase 68 H#K# [002] 68 astrocyte 68 tumor suppressor genes 68 Wnt proteins 68 mutant protein 68 transcriptionally 68 protein encoded 68 VIPR2 68 cell signaling pathway 68 chaperone proteins 68 Th2 68 β2 68 glycosyltransferase 68 MyoD 68 ESCRT 68 DNA demethylation 68 miR #b [001] 68 insulin receptors 68 transcriptional repression 68 SOX9 68 NADPH oxidase 68 apoptotic cell 68 miR #a [001] 68 basophils 68 ß1 68 alveolar epithelial cells 68 myofibroblast 68 CCR9 68 matrix metalloproteinases MMPs 68 estrogen receptors 68 transgenic mouse model 68 osteoclast 68 FasL 68 gliosis 68 phagocytosis 68 synuclein 68 TRPV4 68 focal adhesions 68 NF KB 68 Runx2 68 CHD7 68 TERT 68 CD#c 68 VHL gene 68 P cadherin 68 miR# 68 γδ T cells 68 mice lacking 68 stromal cells 68 EphA2 68 JAK2 68 hepatic stellate cells 68 Th1 cells 68 thyrotropin 68 Kv#.# 68 FGF signaling 68 palytoxin 68 IGF IR 68 tumor microenvironment 68 mutant huntingtin protein 68 PPAR γ 68 Smad 68 cytoskeletal 68 PIP2 68 Stat5 68 cofilin 68 superoxide dismutase 68 KLF2 68 glycosylated 68 epithelial tissue 68 MEK1 68 ERBB4 68 ERBB2 68 p# alpha [001] 68 signaling pathways 68 beta arrestin 68 PI3 kinase 68 Akt signaling 68 proinflammatory 68 Nrf2 68 estrogen receptor beta 68 microRNAs miRNAs 68 DLX5 68 glycogen synthase kinase 68 cyclin E 68 prostate epithelial cells 68 BCL2 68 secretory pathway 68 SMN1 68 tumorigenicity 68 receptor protein 68 HER2 neu 68 progranulin 68 isoforms 68 enzymatic pathways 68 uPA 68 serine threonine 68 Rb#/p# 68 cholinergic neurons 68 caspase activation 68 Arp2 3 68 cholesterol homeostasis 68 DEAR1 68 acetylation 68 mPGES 1 68 p# mitogen activated 68 elastase 68 mTOR pathway 68 vascular permeability 68 H#K# [001] 68 cell signaling pathways 68 NFKBIA 68 TSC1 68 PU.1 68 homodimer 68 CD#L 68 secreted protein 68 IRF6 68 pDC 68 CRAC channel 68 TGFbeta 68 invadopodia 68 adaptive immunity 68 angiogenic 68 glioma cells 68 p# mutations 68 epithelial tissues 68 ERK1 68 pleiotropic 68 LPS induced 68 glutamate signaling 68 methylation patterns 68 peroxisome proliferator activated 68 chromatin structure 68 Factor VEGF 68 posttranslational modifications 68 Sox9 68 myo inositol 68 gastrin 68 chondrocyte 68 Hh signaling 68 phosphorylated 68 Runx1 68 retinoid X 68 neurotransmitter glutamate 68 phosphoprotein 68 Upregulation 68 RIP1 68 hnRNP 68 focal adhesion kinase FAK 68 immunoregulatory 68 spermatogenesis 68 leptin receptor 68 TMEM#B 68 Leydig cell 68 downstream effectors 68 Id1 68 Neurogenesis 68 arginase 68 gene p# 68 dystroglycan 68 serine proteases 68 adrenal cortex 68 β1 68 RNA splicing 68 GRK2 68 immunoreactivity 68 Skp2 68 osteocalcin 68 integrin 68 exocytosis 68 tumor stroma 67 osteoclast formation 67 cellular senescence 67 receptor signaling 67 proteolytic cleavage 67 Sox2 67 Cyclin E 67 p# INK4a 67 NOTCH1 67 IL #p# 67 dynamin 67 factor BDNF 67 suppressor cells 67 glomerular 67 epigenetic modification 67 CagA 67 cytokine receptor 67 spermidine 67 downregulates 67 thymocytes 67 cyclic adenosine monophosphate cAMP 67 mitochondrial enzyme 67 GTPases 67 microglial cells 67 TLR2 67 peroxisomal 67 TNFR 67 chromatin remodeling 67 clonogenic 67 osteopontin 67 mediated apoptosis 67 gene rearrangements 67 glial cell 67 missense mutation 67 Cadherin 67 collagen VI 67 cyclic AMP cAMP 67 PI3K pathway 67 calcium homeostasis 67 pathophysiological 67 matrix metalloproteinase 67 tyrosine kinases 67 PKCi 67 cypin 67 F actin 67 peroxisome 67 p# mutation 67 tumor suppressor p# 67 MECP2 gene 67 PTHrP 67 MMP2 67 PKM2 67 endothelial nitric oxide synthase 67 cardiolipin 67 apoptotic 67 chromosomal rearrangement 67 oncomodulin 67 Cx# [001] 67 mTOR mammalian target 67 splenocytes 67 insulin signaling pathway 67 murine model 67 neoplastic 67 SIRT6 67 mutated protein 67 glucocorticoid receptors 67 pro inflammatory cytokine 67 RAR beta 67 E3 ubiquitin ligase 67 Sir2 67 EGFr 67 thrombospondin 67 hypothalamic pituitary adrenal axis 67 presynaptic 67 bcl 2 67 mesenchymal cells 67 PIP3 67 caspases 67 casein kinase 67 primary cilium 67 ARF1 67 survivin 67 PHD2 67 CB2 receptor 67 Notch pathway 67 steroidogenic 67 neurotrophins 67 VEGF expression 67 neuronal migration 67 downstream effector 67 chemokine receptor 67 endothelial cell 67 prostaglandin E2 67 tissue fibrosis 67 SOD1 protein 67 SATB1 67 mammary cells 67 intracellular signal transduction 67 missense mutations 67 bone morphogenic protein 67 neurotrophic 67 acetylcholine receptor 67 genes encoding 67 pancreatic endocrine 67 effector function 67 Eg5 67 Klf4 67 ENaC 67 monocytes macrophages 67 motoneurons 67 nAChRs 67 synaptic transmission 67 neuronal degeneration 67 Th# cells 67 AMPA receptor 67 histone modification 67 receptor alpha 67 constitutively activated 67 PAK1 67 EphB2 67 T lymphocyte 67 protein conformation 67 phosphate S1P 67 receptor gene 67 endogenous ligand 67 phospho 67 caveolae 67 cholesterol metabolism 67 protein kinases 67 chromosomal instability 67 oncogenic proteins 67 proteolytic processing 67 histone methylation 67 CD8 + 67 neuroligins 67 endonuclease 67 Pin1 67 SOD1 67 GPR# [002] 67 Pdx1 67 epithelial cell 67 neuronal apoptosis 67 HMG CoA reductase 67 NF kappaB pathway 67 interferon γ 67 #BP# 67 overexpression 67 polyamines 67 leukocyte adhesion 67 HbF 67 hypothalamic pituitary 67 microtubule dynamics 67 Immunohistochemical analysis 67 endogenous ligands 67 SIRT1 gene 67 allergic inflammation 67 SLC#A# [002] 67 Macrophage 67 B7 H1 67 secretory 67 tau protein 67 morphogen 67 hippocampal neurons 67 striated muscle 67 bronchial epithelial cells 67 mutant proteins 67 glycosylation 67 membrane fusion 67 ErbB4 67 transcriptional machinery 67 FOXO 67 ERK5 67 ARNT 67 synovial cells 67 RKIP 67 striatal dopamine 67 gastric carcinogenesis 67 HOX genes 67 microvascular endothelial cells 67 CYP#B# 67 P selectin 67 miR #a [002] 67 SCD1 67 melatonin receptor 67 pleiotropic effects 67 Kupffer cells 67 SH#B# 67 motor neuron degeneration 67 chemoresistance 67 TTR gene 67 Rho GTPases 67 neuronal cells 67 PARP inhibition 67 TRPV1 receptors 67 LNCaP cells 67 biogenesis 67 signaling cascade 67 cytoprotective 67 IFNg 67 Overexpression 67 EGFRvIII 67 myopathies 67 tyrosine phosphatase 67 glial 67 nitrotyrosine 67 EBNA1 67 Mdm2 67 mitochondrial proteins 67 metalloproteases 67 Wnt#b 67 neurotrophin 67 PINK1 67 MEK ERK 67 oncogenes 67 chitinase 67 SOD2 67 Caspase 67 VEGFR2 67 PI3K Akt 67 retinoblastoma protein 67 Methylation 67 UCP1 67 oligodendrocyte 67 microRNA miR 67 induce apoptosis 67 LXRs 67 beta adrenergic receptors 67 extramedullary 67 synthetase 67 GABAergic 67 NHEJ 67 polyamine 67 ZNF# 67 erythrocytes 67 c myc gene 67 carcinoembryonic antigen 67 effector functions 67 trophoblast cells 67 stellate cells 66 Sirt1 66 signaling molecule 66 FANCD2 66 receptor molecule 66 CIB1 66 Tie2 66 RNAi pathway 66 TACI 66 ectoderm 66 tRNA synthetase 66 apoE4 66 phosphorylate 66 neutrophil recruitment 66 dysregulated 66 dopaminergic neurons 66 fascin 66 EGFR protein 66 hematopoietic 66 guanosine 66 K + ATPase 66 ChR2 66 IGFBP 3 66 extracellular 66 endocytosis 66 phospholipase 66 Aâ 66 GATA4 66 transcription factors 66 miRNA expression 66 oxidative phosphorylation 66 transgenic mice expressing 66 TRPV3 66 Fibroblast 66 substrate specificity 66 isotypes 66 brain derived neurotrophic 66 endocytic 66 isoenzyme 66 MDSCs 66 downregulated 66 chemokine receptors 66 adipogenesis 66 glutamatergic 66 Ago2 66 chemotactic 66 NMDAR 66 H2AX 66 pathogenic mechanisms 66 hedgehog pathway 66 IRS1 66 GSK3 66 N myc 66 CD4 + CD# 66 Epstein Barr Virus EBV 66 CD#b 66 LDLR 66 factor EGF 66 gastric carcinomas 66 Androgen receptor 66 IFRD1 66 Stat3 66 NF κB activation 66 T lymphocytes 66 NFKB 66 glutamate receptor 66 subcellular localization 66 Angiotensin converting enzyme 66 RRM1 66 dimerization 66 aberrantly activated 66 amyloid deposition 66 retinal ischemia 66 glutamate receptors 66 CENP E 66 protein tau