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(Click for frequent words.) 78 selective inhibition 78 serine threonine 77 M1 muscarinic 77 mediated inhibition 77 ERK1 2 76 cytoprotective 76 TNFalpha 76 anti apoptotic 75 neurite outgrowth 75 CEACAM1 75 HIF 1α 75 TGF beta1 75 ERK signaling 75 cell adhesion molecule 75 c MYC 74 upregulates 74 eNOS 74 FasL 74 antiproliferative activity 74 NKG2D 74 serine protease 74 cyclic adenosine monophosphate cAMP 74 pro apoptotic 74 receptor subtypes 74 SIRT2 74 HIF 1alpha 74 MEK1 74 PPARγ 74 5 HT2A serotonin 74 cyclic AMP cAMP 74 tyrosine phosphorylation 74 TGF ß 74 deacetylation 74 γ secretase 74 pro angiogenic 74 IL 1ß 74 IL #p# 74 Protein Kinase C 74 Upregulation 74 protein tyrosine phosphatase 1B 74 polyamine 74 ACh 74 RAS RAF MEK 74 receptor kinase 74 inhibitory effects 74 immunostimulatory 74 pathophysiological effects 74 proteoglycan 73 proapoptotic 73 immunomodulatory effects 73 mitogen activated protein kinase 73 potent inhibition 73 ERalpha 73 HIF 1a 73 hypoxia inducible factor 73 isoenzyme 73 glutamatergic 73 somatostatin 73 neurotrophic 73 adipogenic 73 PDGFR 73 potent antiproliferative 73 thymidylate synthase TS 73 TRAIL induced apoptosis 73 IFN γ 73 downregulates 73 cytokine signaling 73 FKBP# 73 immunoregulatory 73 pleiotropic 73 PI3K/mTOR 73 Aâ 73 p#Kip# 73 MAP kinase 73 nitrotyrosine 73 prostanoid 73 cyclooxygenase 2 73 muscarinic 73 mitogenic 73 mGluR2 NAM 73 cyclooxygenase COX 73 immune modulating 73 phosphoinositide 73 Akt activation 73 selective agonist 73 androgen receptor AR 73 colony stimulating factor 73 TNF α 73 AT1R 73 mineralocorticoid 73 p# MAPK 72 PHD2 72 dephosphorylation 72 ERK phosphorylation 72 covalently bound 72 p# activation 72 autophagic 72 serine threonine kinase 72 STAT1 72 acetylcholine receptor 72 BMAL1 72 c MET 72 protein tyrosine phosphatase 72 acetylcholinesterase AChE 72 inducible nitric oxide synthase 72 Vascular endothelial growth 72 activin 72 noradrenergic 72 receptor antagonism 72 regulated kinase 72 phospholipase 72 immune modulatory 72 extracellular signal 72 microsomal 72 VEGF receptor 72 mTOR mammalian target 72 phosphorylates 72 adrenoceptor 72 modulatory 72 Cathepsin B 72 catenin 72 Hypoxia Inducible Factor 72 MEK ERK 72 IL6 72 Clusterin 72 c fos 72 PTHrP 72 anaphase promoting complex 72 ERK pathway 72 downregulation 72 induces apoptosis 72 p# alpha [001] 72 constitutively active 72 anti proliferative 72 Eg5 72 Fibroblast Growth Factor Receptor 72 dopamine transporter 72 cyclin dependent kinase inhibitor 72 mRNA expression 72 selectively binds 72 thrombin receptor 72 Histone deacetylase 72 vasoactive 72 PPARgamma 72 PPARg 72 receptor inhibitor 72 Dysregulation 72 prostaglandin synthesis 72 selective antagonist 72 TMEM#B 72 endothelial nitric oxide synthase 71 lipoxygenase 71 #HT#A 71 COX2 71 NF kappaB activation 71 LPS induced 71 JAK#/JAK# 71 NFkappaB 71 receptor tyrosine kinase 71 NO synthase 71 glucagon receptor 71 cyclase 71 decarboxylase 71 TXNIP 71 Extracellular 71 TNFa 71 CGRP 71 phosphoprotein 71 oxidative phosphorylation 71 glucocorticoid receptor 71 ERa 71 antiangiogenic 71 Amino acid 71 inverse agonist 71 nitric oxide synthase NOS 71 eicosanoid 71 selective modulator 71 Rab5 71 p#NTR 71 IGF1R 71 peroxisome proliferator activated 71 transcriptional activation 71 proinflammatory 71 heparanase 71 fatty acid oxidation 71 HepG2 cells 71 Th1 type 71 GABAergic 71 prostaglandin E2 PGE2 71 TGR5 71 cell adhesion molecules 71 nitric oxide synthase 71 IL 1β 71 Signal transduction 71 N acetyl 71 #ß 71 Hedgehog signaling 71 effector function 71 Oncogenic 71 GHRH 71 transcriptional repressor 71 Phosphorylation 71 potently inhibit 71 MT1 MMP 71 dose dependently 71 monocyte chemotactic protein 71 FGFR1 71 mediated apoptosis 71 inflammatory cytokine 71 PTP 1B 71 glycolytic 71 calcitonin gene related 71 phosphatidylinositol 3 71 Abeta# 71 ERK activation 71 guanosine 71 microglial activation 71 PDGF receptor 71 enkephalin 71 serotonin reuptake 71 Cyclin E 71 chemokine receptor 71 nicotinic acetylcholine receptor 71 LTB4 71 P2X 71 regulated kinase ERK 71 Mutational 71 BCL2 71 microglial 71 PDE1 71 intracellular signaling 71 pRb 71 NFκB 71 1α 71 pDC 71 kinase pathway 71 metalloproteinase 71 synaptogenesis 71 Interferon beta 71 selectively inhibited 71 siRNA mediated 71 Ca2 + 71 Histone 71 mRNA encoding 71 Smad3 71 LRP5 71 MMP9 71 CYP#A# CYP#D# 70 factor HGF 70 FGFR3 70 D aspartate 70 IL 1beta 70 iNOS 70 ENaC 70 casein kinase 70 antiproliferative effects 70 isoenzymes 70 HDAC6 70 ligand TRAIL 70 JAK2 enzyme 70 neuronal dysfunction 70 Overexpression 70 intracellular accumulation 70 1beta 70 antisense inhibition 70 galectin 70 UCP1 70 eIF4E 70 ß amyloid 70 Rap1 70 tyrosine hydroxylase 70 protein tyrosine kinase 70 TGFβ 70 thromboxane A2 70 vWF 70 fast skeletal troponin 70 dopamine D2 70 cyclooxygenase 70 ß1 70 osteoblast 70 Nedd4 70 erythropoiesis 70 apoptosis inducing 70 NKX#.# 70 potentiation 70 posttranslational modification 70 glycosylated 70 degranulation 70 FGFR4 70 CRAC channel 70 alpha subunit 70 PKC isoforms 70 anti CD3 70 RRM1 70 redox active 70 constitutively expressed 70 vasodilatory 70 upregulating 70 leptin signaling 70 MMP2 70 Angiotensin II 70 PARP1 70 MAPK pathway 70 E#F# 70 TrkB 70 cholecystokinin CCK 70 vascular endothelial 70 PI3 kinase 70 β catenin 70 coexpression 70 transgenic mice expressing 70 interferon IFN 70 interleukin IL -# 70 CCR9 70 Nampt 70 transgene expression 70 PEDF 70 Fibroblast Growth Factor 70 Fc receptor 70 4E BP1 70 HDAC2 70 oligomerization 70 Notch1 70 renal fibrosis 70 ligand induced 70 norepinephrine reuptake inhibition 70 ß catenin 70 neuronal signaling 70 CDK inhibitor 70 potentiating 70 ADAMTS# 70 TRPV4 70 synthases 70 acyltransferase 70 mitochondrial respiration 70 osteoblastic 70 proto oncogene 70 DNMT1 70 p#/CBP 70 act synergistically 70 5 HT1A 70 TIMP 1 70 Akt signaling 70 superoxide dismutase 70 sGC 70 adipogenesis 70 NADPH 70 vimentin 70 immunomodulation 70 histone acetylation 70 neuronal nitric oxide synthase 70 HCV replication 70 IGFBP2 70 frataxin 70 serotonin receptor 70 acyl CoA 70 EGFR signaling 70 CB2 receptor 70 Galectin 70 NFAT 70 PI3K Akt 70 paxillin 70 FGFs 70 FGF2 70 aminobutyric acid 70 ectopic expression 70 Tubulin 70 c Fos 70 osteoclast formation 70 DNA intercalator 70 lymphangiogenesis 70 dimeric 70 Rho kinase 70 mineralocorticoid receptor 70 protease activated 70 tumor suppressive 70 naturally occurring molecule 70 Dehydrogenase 70 c Src 70 Endothelin 70 induced apoptosis 70 methyl D aspartate 70 CagA 70 CCR2 70 1alpha 70 TNFα 70 p# subunit 70 elastase 70 hydrolase 70 GLI1 70 mitochondrial biogenesis 70 agonism 70 carcinoembryonic antigen 70 heme oxygenase 70 immuno modulatory 70 transient receptor 70 partial agonist 70 Wnt beta catenin 70 Sgk1 70 serotonergic 70 NMDAR 70 GABAB receptors 70 amyloid β 70 Treg cell 70 neurotrophin 69 TGF β 69 CTGF 69 costimulation 69 transferase 69 selectively inhibits 69 receptor blocker 69 69 coactivator 69 Topoisomerase II 69 PGC 1α 69 T#M 69 caveolin 1 69 siRNA knockdown 69 p# MAP kinase 69 PC# cells 69 receptor activation 69 Flt3 69 diphosphate 69 beta actin 69 hydroxylase 69 aberrantly activated 69 5 HT2A 69 oncogenic transformation 69 Adenosine 69 coactivators 69 transgenic mouse models 69 urate oxidase 69 #β estradiol 69 potent suppressor 69 TGF b 69 SGLT 69 costimulatory 69 sphingolipid 69 protein kinase C 69 Adrenergic 69 matrix metalloproteinases 69 HDACi 69 mTOR signaling pathway 69 uPAR 69 lysosomal 69 CYP #D# 69 autocrine 69 ENMD # 69 NK1R 69 ERBB2 69 H#K#me# 69 peroxynitrite 69 guanylate cyclase 69 UCP2 69 leukotriene B4 69 peroxidation 69 IGFBP 3 69 NFkB 69 SCD1 69 P#X# 69 5alpha reductase 69 Dopaminergic 69 mTOR signaling 69 miR #a [001] 69 cAMP signaling 69 NR2B subunit 69 Smoothened 69 nicotinic receptor 69 receptor subtype 69 cytokine receptor 69 5 HT1A receptor 69 CD# CD# 69 serpin 69 glutamate receptors 69 DNA methyltransferases 69 AMPA receptor 69 adrenergic receptors 69 fibrotic disease 69 Tie2 69 matrix metalloproteases 69 estrogen receptor alpha 69 Lyn kinase 69 histone deacetylases 69 TGF alpha 69 5 hydroxytryptamine 69 extracellular dopamine 69 RANK Ligand 69 dependent protein kinase 69 KLF4 69 antitumoral 69 estrogen receptor beta 69 beta subunit 69 transmembrane receptor 69 interleukin 1β 69 receptor CXCR4 69 Aldosterone 69 phosphorylate 69 potently inhibited 69 secretase 69 mitogen activated protein 69 radiosensitivity 69 CDKs 69 immunoreactivity 69 adipocyte 69 ErbB1 69 glycogen synthase kinase 69 Fas ligand 69 DGAT1 69 neuronal differentiation 69 tau phosphorylation 69 inhibitory activity 69 Protelos R 69 GPx 69 retinoid X 69 cyclic nucleotide 69 reductase 69 receptor gamma 69 Fc fusion protein 69 potent inducer 69 IL #E 69 5HT 69 microtubule dynamics 69 dopaminergic 69 proteolysis 69 constitutive activation 69 overactivation 69 antiproliferative 69 FUS1 69 ABCA1 69 cytochrome P 69 messenger ribonucleic acid 69 osteogenic 69 adhesion molecule 69 CCL# 69 lymphocyte activation 69 thrombospondin 69 matrix metalloproteinases MMPs 69 immunomodulatory 69 cytosolic 69 allopregnanolone 69 heme oxygenase 1 69 CYT# potent vascular disrupting 69 TSLP 69 interleukin 1beta 69 5 lipoxygenase 69 S#P# 69 beta adrenergic 69 adenylate cyclase 69 transcriptional activity 69 5 HT2C receptor 69 NF KB 69 mitogen 69 monocytes macrophages 69 substrate specificity 69 drug metabolizing enzyme 69 ornithine decarboxylase 69 PDE#A 69 vascular endothelial cells 69 TrkA 69 superoxide dismutase SOD 69 HER1 69 N methyl 69 glucocorticoid 69 oligomeric 69 MAPK signaling pathway 69 TGF ß1 69 IL 1Ra 69 beta amyloid peptide 69 mitotic progression 69 acid GABA 69 potent inhibitors 69 ErbB4 69 anti inflammatory cytokine 69 hepatocyte growth 69 Interferon gamma 69 Inhibitory 69 related apoptosis inducing 69 phospho 69 peptide hormone 69 acetyltransferase 69 Secretase 69 arginase 69 type glutamate receptor 69 pertussis toxin 69 miR #a [002] 69 synthetase 69 adenosine receptor 69 LRP6 69 natriuretic 69 PLA2 69 Runx2 69 5 HT4 receptor 68 TORC2 68 Factor VEGF 68 EGFr 68 tyrosine kinase receptor 68 Androgen receptor 68 FLT3 68 hypothalamic pituitary adrenal axis 68 phosphate S1P 68 Macrophage 68 muscarinic receptors 68 IAP inhibitor 68 striatal dopamine 68 MAP kinases 68 Kv#.# 68 orally bioavailable mimics 68 mitogen activated protein kinases 68 calcineurin 68 inhibitory neurotransmitters 68 PPAR γ 68 induced phosphorylation 68 gamma aminobutyric acid GABA 68 somatostatin receptor 68 colon carcinoma 68 hydrolases 68 Cytochrome 68 dihydrofolate reductase 68 prostaglandin E 68 VIPR2 68 Lp PLA 2 68 catabolism 68 histone deacetylase inhibitor 68 F actin 68 antitumour 68 Fibroblast 68 EGF receptor 68 cyclic AMP 68 NF κB 68 β amyloid 68 Bcl xL 68 dimerization 68 Symadex 68 lymphotoxin 68 Tumor Necrosis Factor 68 fibrin deposition 68 uricase 68 PPAR peroxisome proliferator activated 68 adenosine diphosphate ADP 68 MnSOD 68 BMP signaling 68 K + ATPase 68 phosphatases 68 HMG CoA reductase 68 serine proteases 68 humanized monoclonal 68 GSTP1 68 intracellular uptake 68 cholesterol biosynthesis 68 phosphorylase 68 CCR1 68 #beta HSD1 68 depolarizing 68 phosphatidylinositol 68 JAK STAT 68 selectively inhibiting 68 antibody mediated 68 HER3 68 MET VEGFR2 68 cyclin dependent kinases 68 hydroxylation 68 steroidogenic 68 5 HT2A receptor 68 demethylation 68 nAChR 68 nNOS 68 Factor Receptor 68 potently inhibits 68 mitochondrial enzyme 68 histone acetyltransferase 68 cytochrome P# 68 NK1 68 tryptase 68 Catenin 68 beta adrenergic receptors 68 CYP #A# 68 esterase 68 potent cytotoxic 68 cytidine 68 monoamine 68 Rho GTPases 68 Tumor necrosis factor 68 induce apoptosis 68 alpha7 68 alpha MSH 68 chemokine SDF 1 68 E cadherin expression 68 intracellular signal transduction 68 transgenic mouse model 68 neurofibromin 68 caveolin 68 antiinflammatory 68 ERK1 68 nAChRs 68 S6K 68 endogenous ligands 68 SYN# 68 endothelial activation 68 peptide CGRP 68 VE cadherin 68 JNK1 68 Beta catenin pathway 68 receptor PPAR 68 potent anti angiogenic 68 GABAA receptors 68 MDR1 68 kallikrein 68 keratinocyte 68 glucokinase 68 transcriptional regulator 68 GSK3B 68 endoplasmic reticulum stress 68 epithelial sodium 68 glycosyltransferase 68 apoptotic pathway 68 prostaglandin E2 68 androgenic 68 Cdc7 68 GAPDH 68 leukotriene 68 adrenocortical 68 neurotransmitters serotonin 68 ubiquitylation 68 antimitotic 68 mevalonate 68 CaM 68 ABL1 68 ErbB receptors 68 histone deacetylase HDAC 68 VEGFR1 68 IFN gamma 68 thymidine kinase 68 plasminogen activator inhibitor 68 selective agonists 68 chromosome condensation 68 TNFR 68 Cytochrome P# 68 ErbB 68 peroxidase 68 inflammasome 68 lysophosphatidic acid LPA 68 GPR# [002] 68 GLP1 68 potent inhibitor 68 Inosine 68 pyrimidines 68 glutamyl 68 TRPV1 receptors 68 integrin receptor 68 intestinal permeability 68 plasmacytoid dendritic cells 68 eotaxin 68 myofibroblast 68 motilin 68 P cadherin 68 IFN g 68 Angiotensin 68 splice variants 68 astrocytic 68 triphosphate 68 downregulate 68 5 HT6 receptor 68 methyltransferase 68 interleukin IL -6 68 neuro protective 68 immune modulator 68 haematopoietic 68 Leydig cell 68 stem cell pluripotency 68 PTPN# 68 Rho GTPase 68 MAPK 68 hepatic lipase 68 SOCS3 68 ESR1 68 Wnt signaling pathway 68 nicotinic acetylcholine receptors 68 endogenous ligand 68 transduction 68 ligand receptor 68 nicotinic 68 metabolizing enzymes 68 selectively inhibit 68 TET2 68 acetyl L carnitine 68 peroxisomal 68 RAR beta 68 RANTES 68 TTR gene 68 PON1 gene 68 #ME# 68 Protein kinase 68 threonine 68 glycogen synthase 68 matrix metalloproteinase 68 experimental autoimmune encephalomyelitis 68 deacetylase 68 GMX# 68 xanthine 68 oxidase 68 hexose 68 endothelin receptor 68 smooth muscle myosin 68 glomerular 68 TGF beta pathway 68 RIP1 68 RhoA 68 thioredoxin 68 peptide receptor 68 c myc 68 homodimers 68 immunoreactive 68 phospholipase C 68 potent inhibitory 68 potent anticancer 68 drug metabolizing enzymes 68 innate immune responses 68 mGluR5 antagonist 68 PDZ domain 68 LPA1 receptor 68 HuR 68 p# mitogen activated 68 TLR2 68 Aß 68 protein phosphatase 68 tumorigenicity 68 interferon γ 68 cathepsins 68 metalloprotease 68 Angiotensin converting enzyme 68 insulin sensitizing 68 BRAF kinase 68 proteolytic 68 transmembrane protein 68 RANKL 68 superoxide anion 68 AT1 receptor 68 IFN ß 68 hypoxia inducible 68 neuroprotective properties 68 monomeric 68 neuropeptide Y NPY 68 soluble tumor necrosis 68 rhIL 7 68 erythropoietin receptor 68 enzyme inhibitor 68 A3 adenosine receptor 68 thyrotropin 68 dehydrogenases 68 SH2 domain 68 immunotoxin 68 triggers apoptosis 67 osteoclast activity 67 coronary vasodilation 67 enzymatic pathways 67 nicotinamide adenine dinucleotide 67 excitotoxic 67 downstream effector 67 overexpressing 67 cytokine receptors 67 SERCA2a 67 transduced 67 calcium calmodulin dependent 67 D aspartic acid 67 cytostatic 67 myeloid derived 67 intestinal absorption 67 oxidative enzymes 67 uroguanylin 67 downregulated 67 Pgp 67 ligand binding 67 Tasimelteon 67 PDE4 67 Phenylalanine 67 subcellular localization 67 Janus kinase 67 antiangiogenic activity 67 prolyl 67 serotonin synthesis 67 Cyclin D1 67 recombinant erythropoietin 67 presynaptic 67 selective adenosine 67 gamma aminobutyric acid 67 AMACR 67 mda 7 67 endoxifen 67 acadesine 67 EP4 67 gene polymorphisms 67 antisense inhibitors 67 Alpha lipoic acid 67 PDGF BB 67 Nod1 67 Prolactin 67 SGLT2 67 anti neoplastic 67 tropomyosin 67 pDCs 67 upregulate 67 cytochrome P# #A# 67 murine model 67 HER2 neu 67 inhibitory effect 67 virulence genes 67 PI3K/AKT 67 cytokines IL 67 osteoblast differentiation 67 Mcl 1 67 CCR3 67 lipoic acid 67 glucose transporter 67 Nicotinic 67 apoptosis pathway 67 platelet activation 67 secreted protein 67 Neurogenesis 67 pyrimidine 67 Myostatin 67 XL# inhibits 67 voltage gated 67 toxic beta amyloid 67 ouabain 67 syntaxin 67 HIF PH 67 allergic inflammation 67 upregulation 67 Nicotinamide 67 ribosomal protein 67 COL#A# 67 peptidomimetic 67 tyrosinase 67 opioid receptor 67 fatty acid synthase 67 signaling cascades 67 HCV protease 67 glucocorticoid receptors 67 GPI anchored 67 mu opioid 67 EP1 receptor 67 Htt 67 glutathione peroxidase 67 NMDA N 67 Neuropeptide Y 67 anti inflammatory cytokines 67 Jhdm2a 67 anti fibrotic 67 Pim kinases 67 Enkephalin 67 glutamate receptor 67 eIF2 67 vanilloid receptor 67 Muscarinic 67 5 HT2B receptor 67 proteolytic cleavage 67 Reductase 67 NS#/#A protease 67 Kinases 67 lipogenesis 67 cytotoxic T lymphocyte 67 vascular disrupting agents 67 osteocalcin 67 endogenous cannabinoids 67 MMP7 67 Glucocorticoid 67 antitumor 67 kinase inhibition 67 basic fibroblast 67 Transferrin 67 agonists antagonists 67 anti atherogenic 67 leukocyte adhesion 67 cytotoxicity assays 67 tyrosine kinase 67 Polymorphisms 67 tumor antigen 67 cyclin dependent kinase 67 NQO1 67 TGF β1 67 Aurora kinase 67 erythropoietic 67 gastric carcinogenesis 67 EGFR receptor 67 pharmacological inhibition 67 gamma glutamyl 67 Peroxisome proliferator activated 67 HDAC enzymes 67 renin angiotensin aldosterone 67 S#A# [002] 67 LNCaP cells 67 cytochrome oxidase 67 guanine nucleotide exchange 67 Notch signaling 67 CD#L 67 Homeostasis 67 cyclins 67 IKK2 67 HER2 HER2