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(Click for frequent words.) 79 ERK1 2 79 β catenin 78 Smad3 78 TGF ß 77 ERK signaling 77 BMP signaling 77 lysosomal 77 neurite outgrowth 76 p# MAPK 76 Smad4 76 tyrosine phosphorylation 76 myocyte 76 proteolysis 76 deacetylation 76 mitogen activated protein kinase 76 inducible nitric oxide synthase 76 caveolin 76 Rab5 75 renal fibrosis 75 TGF beta1 75 TNFalpha 75 cAMP signaling 75 TGF b 75 Hedgehog signaling 75 VE cadherin 75 pRb 75 melanocyte 75 TNF α 75 Cyclin D1 75 TGF ß1 75 glomerular 75 activin 75 acinar 75 nitric oxide synthase 75 fatty acid oxidation 74 STAT1 74 ectopic expression 74 p#Kip# 74 catenin 74 microglial activation 74 neuronal differentiation 74 eNOS 74 TRPV4 74 PDGFR 74 IL 1β 74 mitogenic 74 podocyte 74 ß catenin 74 epithelia 74 serine protease 74 HepG2 cells 74 MAP kinase 74 Wnt signaling 74 chondrocyte 74 ubiquitylation 74 Notch signaling 74 prostaglandin synthesis 74 p# activation 74 autocrine 74 vimentin 73 TGF β 73 E#F# 73 proteoglycan 73 phagocytosis 73 immunoreactivity 73 acetylcholine receptor 73 DNMT1 73 upregulating 73 vascular endothelial cells 73 hypothalamic pituitary 73 paracrine 73 uPAR 73 mediated inhibition 73 IL 1ß 73 upregulates 73 proto oncogene 73 MT1 MMP 73 PI3K signaling 73 pDC 73 induced apoptosis 73 c Src 73 myocardial tissue 73 proapoptotic 73 proximal tubule 73 IFN γ 73 microglial 73 synaptogenesis 73 proteolytic cleavage 73 dephosphorylation 73 PTPN# 73 transcriptional repressor 73 extracellular signal 73 metalloproteinases 73 GAPDH 73 Oncogenic 73 regulated kinase ERK 73 Notch1 73 leukocyte adhesion 73 vWF 73 ERK pathway 73 epithelial barrier 73 EGFR signaling 73 PGC 1α 73 alveolar epithelial cells 73 astrocytic 73 autoregulation 73 MMP9 73 plasminogen 73 Phosphorylation 73 Macrophage 73 FUS1 73 myogenesis 73 lymphangiogenesis 73 PIP2 72 heme oxygenase 1 72 downregulation 72 secretase 72 RUNX3 72 intestinal epithelium 72 LKB1 72 PTHrP 72 γ secretase 72 iNOS 72 androgen receptor AR 72 Dysregulation 72 hypothalamic pituitary adrenal axis 72 uPA 72 cytokine signaling 72 caveolin 1 72 Fc receptor 72 amyloid β 72 vacuolar 72 perivascular 72 JAK2 enzyme 72 antiapoptotic 72 lymphoid cells 72 SUMOylation 72 Akt activation 72 synaptic transmission 72 transcriptional activation 72 hyperactivation 72 CEACAM1 72 vasodilatation 72 metalloproteinase 72 downregulates 72 fibrin deposition 72 reductase 72 Pten 72 TGFβ 72 Cathepsin B 72 C1q 72 lysosomal enzyme 72 CTGF 72 neuronal dysfunction 72 excitotoxic 72 cytoprotective 72 keratinocyte 72 basophils 72 JAK STAT signaling 72 podocytes 72 superoxide dismutase 72 cystic fibrosis transmembrane conductance 72 NFAT 72 PHD2 72 Hh signaling 72 caspase activation 72 mitogen 72 GluR1 72 myofibroblast 72 neuromuscular junction 72 T lymphocyte 72 intracellular signaling 72 Rap1 72 ERalpha 72 NKT cell 72 cardiac myocytes 72 spermatogenesis 72 matrix metalloproteinases 72 receptor gamma 72 F actin 72 mitochondrial respiration 72 STAT3 signaling 72 leukocyte recruitment 72 phosphorylates 72 p#NTR 72 motoneurons 72 proinflammatory 72 abnormal angiogenesis 71 constitutively expressed 71 IFN gamma 71 phosphatidylinositol 3 71 IL 1beta 71 oxidative phosphorylation 71 mRNA expression 71 constitutively 71 motor neuron degeneration 71 endothelial nitric oxide synthase 71 GLI1 71 CD1d 71 TORC2 71 prostate epithelial cells 71 potent inhibition 71 adipogenic 71 serine threonine kinase 71 nAChR 71 adenylate cyclase 71 upregulation 71 neurotrophic 71 ABCA1 71 NKG2D 71 FasL 71 erythropoiesis 71 cofilin 71 ACh 71 VEGF receptor 71 fibrogenesis 71 homodimers 71 lung epithelium 71 overactivation 71 elastase 71 TGFbeta 71 inflammatory cytokine 71 protein kinase C 71 LRP6 71 IRE1 71 cytoplasmic domain 71 Htt 71 Cadherin 71 HIF 1alpha 71 aberrantly activated 71 estrogen receptor alpha 71 transactivation 71 cell adhesion molecule 71 IL #p# 71 tumorigenicity 71 cholinergic neurons 71 axonal 71 synapse formation 71 mitochondrial biogenesis 71 cholesterol homeostasis 71 Clusterin 71 Bcl xL 71 transthyretin 71 gliosis 71 CCL# 71 LPS induced 71 neuronal signaling 71 Nod1 71 MAPK pathway 71 effector functions 71 cyclooxygenase 2 71 Overexpression 71 exocytosis 71 ouabain 71 cellular senescence 71 neovascularization 71 nitric oxide synthase NOS 71 KCNE2 71 tryptase 71 MyoD 71 E cadherin expression 71 synovial cells 71 adhesion molecule 71 transcriptional regulation 71 IRS1 71 tyrosine hydroxylase 71 antibody mediated 71 anti inflammatory cytokine 71 costimulatory 71 transgene expression 71 adrenal cortex 71 Ca2 + 71 transmembrane protein 71 HIF 1a 71 intestinal mucosa 71 steroidogenic 71 leptin signaling 71 neuronal migration 71 cytosol 71 paxillin 71 nNOS 71 pro angiogenic 71 FANCD2 71 mice lacking 71 synaptic vesicle 71 cytoskeletal 71 heme oxygenase 71 Jhdm2a 71 MMP2 71 GABAergic neurons 71 Immunohistochemical analysis 71 caveolae 71 IFNg 70 #BP# 70 PP2A 70 SOCS3 70 SCD1 70 SMAD4 70 HUVEC 70 prostaglandin E2 70 HCV replication 70 apoptotic pathway 70 vascular endothelial 70 secretory pathway 70 constitutively active 70 muscarinic receptors 70 RANK Ligand 70 MEK1 70 NADPH oxidase 70 histone acetylation 70 cellular prion protein 70 EGF receptor 70 NFkappaB 70 STAT3 70 secretory 70 catabolism 70 eotaxin 70 osteoclast 70 matrix metalloproteinases MMPs 70 induces apoptosis 70 epithelial cells lining 70 Prolactin 70 microtubule dynamics 70 BMAL1 70 osteoblast 70 CXCL# 70 ligand induced 70 isoenzyme 70 Sp1 70 osteoclast activity 70 Factor VEGF 70 Caveolin 1 70 RhoA 70 PC# cells 70 ciliated 70 Endothelial 70 beta adrenergic receptors 70 isoenzymes 70 neuronal degeneration 70 glutamate receptors 70 S nitrosylation 70 axon guidance 70 NPD1 70 ß amyloid 70 epigenetic silencing 70 enzymatic activity 70 mitochondrial enzyme 70 Purkinje cell 70 Fas ligand 70 hypoxia inducible factor 70 cyclic nucleotide 70 NF kB pathway 70 oligomerization 70 calcium homeostasis 70 cell adhesion molecules 70 lymphocyte activation 70 HPA axis 70 striated muscle 70 S#A# [002] 70 SIRT2 70 selective inhibition 70 genotoxic stress 70 tropomyosin 70 polycystin 70 cyclic AMP 70 ERBB2 70 RAS RAF MEK 70 kinase pathway 70 NFκB 70 spectrin 70 ERK activation 70 osteogenic differentiation 70 dopaminergic neurons 70 peroxisomal 70 proteosome 70 CagA 70 PEDF 70 microvascular endothelial cells 70 osteogenic 70 Purkinje cells 70 TAp# 70 Vps# 70 ADAMTS# 70 neutrophil recruitment 70 Wnt pathway 70 NFkB 70 endonuclease 70 4E BP1 70 cofactor 70 miR# 70 c Fos 70 receptor subtype 70 Rac1 70 posttranslational modification 70 Mcl 1 70 actin cytoskeleton 70 PIP3 70 alveolar macrophages 70 dystroglycan 70 Treg cells 70 osteolytic 70 hypoperfusion 70 CD#c 70 TGF β1 70 Th1 cells 70 FGF2 70 Upregulation 70 breast epithelial cells 70 Dpp 70 demyelination 70 ERK phosphorylation 70 amyloid peptide 70 capillary endothelial cells 70 umbilical vein 70 redox active 70 oncogenic transformation 70 Prox1 70 PON1 70 AT1R 70 aberrant activation 70 receptor tyrosine kinase 70 hippocampal neurons 70 hypothalamic 70 NF KappaB 70 degranulation 70 BACE1 70 efferent 70 WNK1 70 antioxidant enzyme 70 endothelial activation 70 NF κB 70 sphingolipid 70 presynaptic 70 lipoxygenase 70 M1 muscarinic 70 ERK2 70 lysyl oxidase 69 ERK1 69 cardiolipin 69 Monocyte 69 proinflammatory cytokines 69 TSLP 69 endothelial 69 FGFs 69 sortilin 69 endocytic 69 N cadherin 69 myofibroblasts 69 Aβ 69 TGF beta signaling 69 trophoblast cells 69 factor HGF 69 acyl CoA 69 GRP# 69 dopaminergic 69 PECAM 1 69 focal adhesions 69 CHD7 69 thioredoxin 69 ß1 69 TrkA 69 cell adhesion 69 progerin 69 occludin 69 glycosyltransferase 69 TGF beta pathway 69 XBP1 69 metabolic enzymes 69 Runx2 69 sGC 69 proteolytic 69 proteinase 69 noradrenergic 69 phosphoprotein 69 desmin 69 ectodomain 69 mutant huntingtin protein 69 MAP kinases 69 c MYC 69 neurofibromin 69 excitatory neurotransmitter glutamate 69 prostaglandin E2 PGE2 69 FGFR4 69 ubiquitination 69 beta subunit 69 POMC neurons 69 cytosolic 69 MAP kinase pathway 69 Smad7 69 TOP2A gene 69 lymphatic vasculature 69 BMP4 69 cyclin B1 69 PPARg 69 monocyte 69 potent inducer 69 PTEN gene 69 ubiquitin ligase 69 downregulated 69 TNFa 69 adrenocortical 69 intercellular communication 69 fibrotic 69 atherogenesis 69 Angiotensin II 69 neoplastic cells 69 apoE 69 anti apoptotic 69 Abeta protein 69 FGF signaling 69 isotypes 69 gluconeogenesis 69 diffusible 69 phagocyte 69 carbohydrate metabolism 69 platelet activation 69 E3 ubiquitin ligase 69 hyperactivated 69 cyclin 69 Wnt signaling pathway 69 epithelial cell 69 gastric mucosa 69 GRK2 69 phosphate S1P 69 beta amyloid peptide 69 Foxp3 69 baroreflex 69 aminopeptidase 69 mTORC1 69 IKK2 69 PKC isoforms 69 LRP5 69 antiproliferative activity 69 oncomodulin 69 CCR7 69 Aâ 69 homodimer 69 Cx# [001] 69 oxidative DNA 69 β1 69 ischemia induced 69 CaM kinase II 69 C EBP alpha 69 neuroinflammatory 69 receptor subtypes 69 LIS1 69 acetylcholinesterase 69 LDL receptor 69 oligomeric 69 glutamatergic 69 potent stimulator 69 neuronal apoptosis 69 Microtubule 69 p# mitogen activated 69 dynamin 69 Dopaminergic 69 transgenic mice expressing 69 IL6 69 TrkB 69 cyclin E 69 circadian clock genes 69 striatal dopamine 69 glycolytic 69 chitinase 69 osteoclast formation 69 Dystrophin 69 oxidase 69 virulence genes 69 calpain 69 tumoral 69 kinase domain 69 GLUT1 69 arginase 69 T#M 69 c MET 69 RANK ligand 69 basolateral 69 ADAM# 69 SMN1 69 humoral 69 erythroid 69 ErbB4 69 innervation 69 apoptotic 69 KLF4 69 pro inflammatory cytokine 69 TIMP 69 Inactivation 69 thyrotropin 69 PARP1 69 polyamine 69 actin polymerization 69 biogenesis 69 NOD2 69 JNK1 69 myo inositol 69 pyrimidine 69 transcriptional repression 69 adenosine receptors 69 FKBP# 69 CD# expression [001] 69 Src kinase 69 tumorigenesis 69 Androgen 69 glycolipids 69 mononuclear 69 VEGFR1 69 alpha Gal 69 NKX#.# 69 GABAA receptors 69 erythrocyte 69 endothelial nitric oxide 69 GABAergic interneurons 69 nitrotyrosine 69 trophoblasts 69 protein tyrosine phosphatase 69 Kupffer cells 69 oxidative metabolism 69 humoral immunity 69 P selectin 69 CD#L 69 aggrecan 69 FGFR1 69 gut mucosa 69 glucokinase 69 pituitary hormone 69 renal tubular 69 c myc 69 H#K#me# 69 mediated apoptosis 69 cytochrome c 69 osteoblastic 69 GABAergic 68 pharmacological inhibition 68 postsynaptic 68 fibrotic disease 68 clonogenic 68 receptor activation 68 Tie2 68 Cdc# 68 inducible 68 striatal 68 Peyer patches 68 CD8 + 68 Hh pathway 68 oxidases 68 inhibitory effects 68 monomeric 68 organogenesis 68 serine proteases 68 contractile function 68 PGE2 68 hydrolase 68 glucose transporter 68 Th1 type 68 N myc 68 catecholamine 68 anterior pituitary 68 mitogen activated protein kinases 68 thymic 68 5 HT1A 68 tumor suppressor protein 68 PrPC 68 cyclic adenosine monophosphate cAMP 68 oligodendrocyte 68 palmitate 68 myelination 68 collagen synthesis 68 interstitium 68 beta arrestin 68 junctional 68 P cadherin 68 interferon γ 68 FGFR3 68 PLA2 68 focal adhesion kinase FAK 68 chromosome condensation 68 COL#A# 68 PDGFR alpha 68 AMPA receptor 68 beta globin gene 68 Neuropeptide Y 68 NR#A# 68 Ras pathway 68 TERT 68 cell motility 68 ATPase 68 osteocalcin 68 TNFR 68 TNFα 68 #ß 68 Sgk1 68 COX2 68 cyclophilin D 68 cell lysis 68 adipocyte 68 interstitial fibrosis 68 osteoblast differentiation 68 beta1 integrin 68 leucine zipper 68 hyperalgesia 68 cytoplasmic 68 vascular permeability 68 p# pathway 68 MAPK 68 miR #a [001] 68 null mice 68 lipoprotein lipase 68 cardiac fibroblasts 68 H#K# [002] 68 tau protein 68 axonal degeneration 68 haematopoietic 68 ENaC 68 oncoprotein 68 calcineurin 68 HIF 1α 68 bone morphogenic protein 68 Epithelial 68 induced neuronal 68 cellular metabolism 68 JAK STAT 68 leptin receptor 68 ABL1 68 mRNA translation 68 pDCs 68 telomere maintenance 68 remyelination 68 peroxynitrite 68 glucose homeostasis 68 cyclin D1 68 leukemic cell 68 RIP1 68 erythrocytes 68 Alu RNA 68 SOD1 68 insulin signaling pathways 68 HDAC2 68 PTP 1B 68 intimal hyperplasia 68 osteoprotegerin 68 E3 ligase 68 bile acid 68 metaphase 68 effector function 68 spermidine 68 NFKBIA 68 TGF beta 68 carcinoembryonic antigen 68 β cells 68 lymphoid 68 excess glutamate 68 chemokine receptor 68 apoptotic cells 68 factor PlGF 68 progranulin 68 palytoxin 68 colocalization 68 dehydrogenase 68 C5aR 68 Hypoxia Inducible Factor 68 Aß 68 aldose reductase 68 airway remodeling 68 Flt3 68 UCP1 68 immunoreactive 68 cadherin 68 Akt signaling 68 MMP# 68 vasodilatory 68 upregulated 68 gene encodes 68 GLUT4 68 Stat1 68 Rab# 68 K + ATPase 68 tumor vasculature 68 thymidylate synthase TS 68 pyrimidines 68 PrP 68 alpha synuclein protein 68 chromosomal rearrangement 68 IKKß 68 experimental autoimmune encephalomyelitis 68 murine model 68 synthetase 68 cerebral ischemia 68 TIMP 1 68 cytokine receptor 68 activate p# 68 retinal ischemia 68 lymphotoxin 68 costimulation 68 EP1 receptor 68 CD#b 68 tau phosphorylation 68 cathepsins 68 UCP2 68 myogenic 68 NF kB 68 cypin 68 urothelium 68 LRAT 68 Oxidative stress 68 malignant transformation 68 eIF2 68 Nkx#.# 68 monocytes macrophages 68 pathophysiological effects 68 DGAT1 68 Skp2 68 BRAF protein 68 chromatin structure 68 bFGF 68 tissue homeostasis 68 cathepsin B 68 PPARγ 68 Notch pathway 68 serotonergic 68 PKC beta 68 ischemia reperfusion injury 68 cytokine 68 Cyclin E 68 matrix metalloproteinase 68 NO synthase 68 HER2 neu 68 cyclins 68 CYP#B# 68 regulates gene expression 68 dimerization 68 TRAIL induced apoptosis 68 inhibits protein synthesis 68 downregulate 68 1alpha 68 chromosomal instability 68 nociceptive 68 lung fibrosis 68 renal tubules 68 toxic beta amyloid 68 serotonin reuptake 68 vascular endothelium 68 pleiotropic 68 NF KB 68 neuropeptide Y 68 Wnts 68 prostaglandin E 68 Thyroid hormone 68 AhR 68 TET2 68 mutant protein 68 SGK1 68 adrenoceptor 68 endoplasmic reticulum stress 68 nigrostriatal 68 proteolytic processing 68 Aldosterone 68 mutant huntingtin 68 innate immune responses 68 HSF1 68 agonist induced 68 retinoic acid receptor 68 Dehydrogenase 68 IRAK1 68 phosphatidylinositol 68 serotonin synthesis 68 synaptic function 68 phospholipase 68 platelet adhesion 68 VEGF expression 68 RANKL 68 cyclooxygenase COX 68 phosphorylate 68 NF kappaB activation 68 striatal neurons 68 gene polymorphisms 68 regulator CFTR protein 68 collagen degradation 67 neurturin 67 messenger molecule 67 adipogenesis 67 CaM 67 Rho kinase 67 dopamine signaling 67 hepatic glucose production 67 type plasminogen activator 67 glial derived neurotrophic 67 plasmin 67 GSK 3ß 67 p# mutation 67 Ago2 67 ependymal cells 67 membrane lipids 67 epithelial tissue 67 tyrosine kinase 67 lymphocytic 67 N Myc 67 murine 67 Smoothened 67 tenascin C 67 endothelial cell 67 intracellular pH 67 hematopoiesis 67 Treg cell 67 signaling cascades 67 polymorphonuclear leukocytes 67 Cytotoxic T 67 hnRNP 67 Wnt beta catenin 67 PTH secretion 67 glutamate receptor 67 casein kinase 67 β amyloid 67 undergo apoptosis 67 cytolytic 67 disulfide bond 67 amyloid deposition 67 GSTT1 67 MyD# 67 intestinal epithelial cells 67 hematopoietic cells 67 thrombin receptor 67 lipid homeostasis 67 tau proteins 67 hydrolases 67 1beta 67 apoE4 67 mineralocorticoid 67 CPEB 67 miRNA expression 67 proton pump 67 TRPV3 67 EAAT2 67 ornithine decarboxylase 67 Vasopressin 67 Amino acid 67 PrPSc 67 choroidal 67 glutathione GSH 67 cardiac fibrosis 67 receptor mediated endocytosis 67 glutamatergic neurons 67 p# protein 67 CB2 receptor 67 NAD + 67 intercellular signaling 67 excitatory neurotransmitter 67 cyclic AMP cAMP 67 endoplasmic reticulum 67 glycogen metabolism 67 intraventricular 67 inflammasome 67 neurotransmitter GABA 67 induce apoptosis 67 E selectin 67 receptor signaling 67 p# Shc 67 ARF1 67 basic fibroblast 67 insulin receptors 67 hypoxic tumor 67 FOXO1 67 telomere dysfunction 67 phospho 67 p# MAP kinase 67 lipid peroxides 67 tumor suppressor gene 67 EGFR expression 67 receptor inhibitor 67 skeletal muscle cells 67 serine threonine 67 metalloproteases 67 hypothalamic pituitary axis 67 telomeric 67 Nedd4 67 HBx 67 splenocytes 67 acetyltransferase 67 bone morphogenetic proteins BMPs 67 synovial tissue 67 endosomal 67 cysteine protease 67 nucleoli 67 raphe 67 H#K# methylation 67 phosphorylated tau 67 enkephalin 67 mitotic progression 67 mTOR signaling pathway 67 macrophage infiltration 67 presenilin 67 p# alpha [001] 67 overactivated 67 TFIIH 67 transmembrane receptor 67 clusterin 67 mRNA decay 67 focal adhesion 67 coexpression