Related by context. All words. (Click for frequent words.) 71 gamma secretase 67 PKC alpha 66 ERK1 2 66 PCSK9 66 COX enzymes 66 Wnt signaling pathway 65 prostaglandin synthesis 65 cyclooxygenase 65 γ secretase 65 enzyme HMG CoA 65 micro RNAs 65 CDK5 65 LDL receptor 65 aldose reductase 65 beta amyloid peptide 65 NADPH oxidase 65 hedgehog pathway 65 sortilin 65 cell signaling pathway 64 costimulation 64 mitogen activated protein kinase 64 cathepsins 64 toxic amyloid beta 64 5 lipoxygenase 64 androgen receptor AR 64 amyloid beta plaques 64 focal adhesion kinase FAK 64 serine protease 64 amyloid ß 63 tumor angiogenesis 63 protein tyrosine phosphatase 1B 63 AT1R 63 CCR3 63 calpain 63 PI3K/Akt pathway 63 renal fibrosis 63 IKK2 63 Src kinase 63 β catenin 63 regulating gene expression 63 tyrosine kinase 63 endothelial nitric oxide 63 casein kinase 63 phosphatidylinositol 3 63 mutant huntingtin 63 E3 ligase 63 enzyme COX 63 aberrantly activated 63 selective inhibition 63 secreted protein 63 toxic beta amyloid 62 protein kinase C 62 MMP2 62 thromboxane A2 62 uPAR 62 GSK3 62 protein fragment 62 HIF 1α 62 Aβ 62 tumorigenesis 62 proto oncogene 62 orexin receptors 62 TGF β 62 enzyme beta secretase 62 matrix metalloproteinases MMPs 62 ERK pathway 62 apoptotic pathway 62 phosphate S1P 62 FasL 62 PGC 1α 62 osteoclast formation 62 ARF1 62 Skp2 62 glucokinase 62 MEK ERK 62 MAP kinase 62 Angiotensin 62 Abeta# 62 catenin 62 neurite outgrowth 62 VEGF receptor 62 c MYC 62 cell adhesion molecules 62 eNOS 62 thioredoxin 62 IL #p# 62 VEGFR 62 RAS RAF MEK 62 potent inhibitors 62 VEGF pathway 62 FGFR1 62 Endothelin 62 Upregulation 62 immunoregulatory 62 acetylcholine receptor 62 cPLA2 61 secretase 61 FANCD2 61 leukotrienes 61 caveolin 1 61 IL 1β 61 osteoclast activity 61 nAChRs 61 Tissue Factor 61 deacetylation 61 neurofibrillary tangles 61 lymphangiogenesis 61 Wnt pathway 61 enzyme aromatase 61 NF kappaB 61 reductase 61 amyloid beta peptides 61 PAK1 61 proapoptotic 61 pRb 61 tau protein 61 p# MAP kinase 61 PKM2 61 glutamate receptors 61 FGFR3 61 mevalonate 61 S1P 61 tenascin C 61 PPARg 61 C5aR 61 nicotinic acetylcholine receptors 61 5 HT2A receptor 61 aromatase 61 nAChR 61 TGF b 61 cellular pathways 61 mediated inhibition 61 cyclooxygenase COX 61 oncoprotein 61 aP2 61 NF KB 61 inhibiting COX 61 LRP1 61 osteoblast differentiation 61 autocrine 61 microglial activation 61 SCD1 61 FGFR 61 FOXO1 61 thyroid hormone receptor 61 fibrogenesis 61 NFkB 61 chemokine receptor 61 serine threonine 61 activin 61 adhesion molecule 61 FGFs 61 acetylcholinesterase AChE 61 HDAC 61 Akt3 61 Pten 61 tumor suppressor protein 61 KLF2 61 neuronal apoptosis 61 GGTase 61 leukocyte adhesion 61 EP1 receptor 61 transcriptional activation 61 gamma aminobutyric acid 61 STAT3 60 SIRT2 60 HMG CoA reductase 60 kinase pathway 60 Cyclin D1 60 MAPK pathway 60 TGF beta 60 LRP6 60 protein beta amyloid 60 Fibroblast Growth Factor Receptor 60 4E BP1 60 alpha glucosidase 60 BACE1 60 cyclin dependent kinases 60 amyloid β 60 p# MAPK 60 synapse formation 60 histone deacetylases 60 neuronal migration 60 NF kB pathway 60 NF kB 60 MT1 MMP 60 Pin1 60 oncogenic signaling 60 IL 1beta 60 neuropeptide Y 60 HDAC6 60 cytokine IL 60 IKKß 60 podocyte 60 Hypoxia Inducible Factor 60 NFκB 60 PDGFR 60 mTOR mammalian target 60 trans splicing 60 c Abl 60 fatty acid synthase 60 HCV replication 60 proteoglycan 60 PP2A 60 pharmacological inhibition 60 TMEM#B 60 mediated apoptosis 60 Hedgehog signaling pathway 60 RNAi pathway 60 inhibit angiogenesis 60 viral proteins 60 MMP9 60 cell adhesion molecule 60 adipogenesis 60 Hedgehog signaling 60 sphingolipid 60 autophagic 60 GLI1 60 glycogen synthase kinase 60 #beta HSD1 60 enzyme cyclooxygenase 60 CB1 receptor 60 antioxidant enzyme 60 SOD1 60 transcriptional repressor 60 DNA intercalator 60 enzyme inhibitor 60 cyclooxygenase 2 60 caspases 60 dimerization 60 hypoxia inducible factor 60 TNFα 60 superoxide dismutase 60 gastrin 60 eotaxin 60 TNFR 60 TGF ß 60 miR# 60 CatB 60 Fas ligand 60 HDACs 60 amyloid beta protein 60 matrix metalloproteinases 60 cyclin B1 60 mutant protein 60 molecular signaling pathway 60 chitinase 60 BMP4 60 TXNIP 60 eicosanoid 60 tRNA synthetase 60 HDAC2 60 pro angiogenic 60 encodes protein 60 mRNA translation 60 RANK Ligand 60 CD# ligand 60 SGK1 60 p# tumor suppressor 60 E#F# 60 clusterin 60 serine threonine kinase 60 alpha synuclein 60 NF kappa B 59 intracellular signaling 59 cyclic adenosine monophosphate cAMP 59 MEK1 59 PKC isoforms 59 inverse agonist 59 selectively inhibited 59 osteoclast 59 demethylase 59 bacterial enzyme 59 EGF receptor 59 ABCA1 59 CXCR2 59 miR #a [002] 59 PI3K Akt 59 poly ADP ribose polymerase 59 nitric oxide synthase 59 osteoblast 59 5 HT2A serotonin 59 PDE5A 59 protease enzymes 59 Aâ 59 CB1 receptors 59 cholesterol homeostasis 59 BMP signaling 59 prostaglandin E2 59 Smad4 59 COX2 59 cannabinoid receptor 59 cytoplasmic domain 59 pyrimidines 59 IGF 1R 59 Wnt signaling 59 enzymatic activity 59 oxidative phosphorylation 59 acinar 59 cdk5 59 osteopontin 59 CCL5 59 cyclic GMP 59 MUC1 * 59 proteinase 59 non coding RNA 59 vWF 59 PPAR alpha 59 CB2 receptor 59 apoE 59 Notch receptor 59 enzyme inhibitors 59 CXCR4 receptor 59 NMDA receptor 59 Rho kinase 59 SIRT1 gene 59 TGF beta pathway 59 TMPRSS6 59 beta catenin protein 59 phosphatases 59 regulated kinase ERK 59 NF κB 59 cyclins 59 prostaglandin E2 PGE2 59 epigallocatechin gallate EGCG 59 lysosomal 59 RUNX3 59 enzyme 59 ERK signaling 59 neurite 59 microtubule dynamics 59 neuronal cell 59 CTLA 4 59 DNA methyltransferases 59 downregulates 59 extracellular signal 59 Rap1 59 Phosphorylation 59 glutamate receptor 59 signaling pathway 59 Clusterin 59 DNA adducts 59 lipid synthesis 59 EZH2 59 genes encode proteins 59 lipoxygenase 59 ubiquitin ligase 59 receptor tyrosine kinase 59 cytokine receptor 59 atherogenesis 59 antioxidant enzymes 59 androgen receptor 59 STAT1 59 apoptosis proteins 59 heme oxygenase 59 frataxin 59 serotonin uptake 59 LKB1 59 selenoproteins 59 Aldosterone 59 mTORC1 59 Htt 59 NMDA receptors 59 phosphatase 59 enkephalin 59 Hedgehog pathway 59 tyrosine phosphorylation 59 TFIIH 59 drug metabolizing enzyme 59 p# activation 59 autophagic cell death 59 synaptogenesis 59 HER1 59 amyloid formation 59 cyclin D1 59 nNOS 59 inhibit enzymes 59 myeloid derived 59 chaperone protein 59 receptor subtype 59 paxillin 59 protein CETP 58 reuptake 58 amyloid deposits 58 FGFR4 58 Nrf2 58 podocytes 58 S#K# 58 GATA3 58 serine proteases 58 FKBP# 58 c myc 58 Akt signaling 58 suppresses tumor 58 CYP#B# 58 DISC1 58 Orexin 58 interleukin 1beta 58 lipoprotein lipase 58 FOXO3a 58 HMG CoA 58 RANKL 58 nicotinamide 58 mitogenic 58 RANK ligand 58 Bcl2 58 c myc gene 58 ceramide 58 Smad7 58 VEGF receptors 58 serotonin receptor 58 TET2 58 overactivation 58 regulates gene expression 58 cellular senescence 58 CFTR cystic fibrosis transmembrane 58 Wnt beta catenin 58 protein tyrosine kinase 58 phosphorylates 58 sphingolipids 58 ENaC 58 Factor Receptor 58 TGF ß1 58 RNA silencing 58 hyperphosphorylation 58 angiotensin receptor 58 secretory pathway 58 furin 58 metabolic enzymes 58 adenosine receptor 58 PEDF 58 endocannabinoid receptors 58 iNOS 58 peroxisome proliferator activated 58 paracrine 58 TSP1 58 constitutively active 58 coactivator 58 endothelial nitric oxide synthase 58 STIM1 58 JAK2 enzyme 58 PI3 kinase 58 cytidine 58 PI3K pathway 58 neurotransmission 58 CRAC channel 58 Smurf1 58 galanin 58 tumor suppressor genes 58 TNFa 58 interleukins 58 TNF α 58 ß amyloid 58 humanized monoclonal antibodies 58 coenzyme 58 cAMP signaling 58 PHD2 58 transthyretin 58 synaptic transmission 58 excitotoxicity 58 PPAR gamma 58 coagulation cascade 58 cell signaling pathways 58 eIF4E 58 mitotic progression 58 VE cadherin 58 antisense inhibitor 58 adenylate cyclase 58 regulate gene expression 58 erythropoiesis 58 gluconeogenesis 58 PAR1 58 inhibiting tumor 58 motor neuron degeneration 58 lipoprotein metabolism 58 NKT cells 58 MAP kinase pathway 58 superoxide 58 bacterial enzymes 58 ADAMTS# 58 Aß 58 ErbB4 58 Akt activation 58 dehydrogenase 58 Th# cells 58 protein encoded 58 prostaglandin D2 58 intracellular signaling pathways 58 CTGF 58 myeloma cells 58 Notch pathway 58 GluR1 58 Smoothened 58 signaling cascades 58 SGLT2 58 synthetase 58 miR #b [002] 58 BCL#A 58 anti apoptotic 58 histamine receptors 58 mutant huntingtin protein 58 airway remodeling 58 tau tangles 58 oncomodulin 58 MAP kinases 58 arginase 58 p# mitogen activated 58 Eg5 58 oligomerization 58 naturally occurring amino acid 58 axonal degeneration 58 cyclic AMP 58 P glycoprotein 58 amyloid protein 58 potent inducer 58 polyamines 58 molecular pathway 58 opiate receptors 58 excitatory neurotransmitter glutamate 58 triptolide 58 Macrophage 58 nicotinic receptors 58 antiapoptotic 58 isoenzymes 58 fatty acid oxidation 58 Flt3 58 Nedd4 58 NRG1 58 receptor gamma 58 tumor suppressor gene 58 endonuclease 58 TGFβ 58 proteolytic 58 PDE1 58 CDK4 58 caspase activation 58 fatty acid metabolism 58 sphingosine 1 58 protein misfolding 57 JAK STAT 57 catabolism 57 EETs 57 peroxidation 57 intracellular proteins 57 RAS RAF MEK ERK 57 proteolytic cleavage 57 induces apoptosis 57 disulfide bond 57 calcineurin 57 Raf kinase 57 CCR2 57 amyloid proteins 57 histone H3 57 beta catenin 57 primary cilia 57 Jagged1 57 endoplasmic reticulum stress 57 integrin 57 LTB4 57 GSK3B 57 Abeta peptide 57 cholesterol metabolism 57 protein kinase 57 Th1 type 57 Notch signaling 57 EphA2 57 IAP inhibitor 57 MAPK 57 Ras pathway 57 LRAT 57 E3 ubiquitin ligase 57 neuronal nicotinic receptors NNRs 57 amyloid precursor protein 57 antiangiogenic 57 insulin signaling pathway 57 DLX5 57 acetylcholinesterase 57 HIF1 alpha 57 PIP2 57 CXCL# 57 vimentin 57 progranulin 57 tumor suppressors 57 dopamine transporter 57 FGFR2 57 proinflammatory cytokines 57 cell motility 57 metalloproteinase 57 cathepsin B 57 mPGES 1 57 Abeta 57 PECAM 1 57 ubiquitylation 57 copper zinc superoxide 57 Stat5 57 myelin repair 57 cytokines IL 57 PI3K AKT 57 Lyn kinase 57 Smad3 57 biosynthesis 57 glucocorticoid receptor 57 inhibit vascular endothelial 57 transmembrane receptor 57 ß catenin 57 VEGF 57 CEACAM1 57 PKC beta 57 Angiotensin II 57 cytokine signaling 57 muscarinic receptors 57 reversible inhibitor 57 ER alpha 57 polyamine 57 peroxisome 57 glucagon receptor 57 Sp1 57 RKIP 57 PARP1 57 fucose 57 Wnts 57 retinoic acid 57 invadopodia formation 57 Akt 57 DHFR 57 BRAF kinase 57 NO synthase 57 PECAM 57 calcium homeostasis 57 vascular endothelial cells 57 Oncogenic 57 IL 1ß 57 biosynthetic pathway 57 Akt1 57 CaMKII 57 neuromuscular junction 57 intracellular accumulation 57 bradykinin 57 acetyl groups 57 oncogenesis 57 protein alpha synuclein 57 neurotransmitter GABA 57 TSLP 57 PPARγ 57 cardiac fibroblasts 57 TNF receptors 57 Six3 57 neovascularization 57 ADAM# 57 USP# 57 pro inflammatory cytokines 57 TAp# 57 p# pathway 57 MEF2 57 CIB1 57 KLF4 57 neurotransmitter glutamate 57 E selectin 57 Hh pathway 57 Aurora kinases 57 cellular signaling pathways 57 mitogen activated protein 57 Bcl xL 57 beta adrenergic 57 GRP# 57 TGF beta1 57 enzyme phosphodiesterase 57 vascular endothelial 57 homodimers 57 oncogenic transformation 57 PIP3 57 caveolae 57 Bcl XL 57 Alu RNA 57 p#Kip# 57 mutant proteins 57 LRRK2 57 cypin 57 mTOR 57 mitochondrial respiration 57 protein phosphatase 57 c Src 57 focal adhesion kinase 57 synovial cells 57 Factor VEGF 57 PPAR peroxisome proliferator activated 57 VEGF signaling 57 neuro protective 57 sGC 57 glucocerebrosidase 57 Rac1 57 p#NTR 57 factor HGF 57 isoprenoid 57 adrenergic receptors 57 VEGF induced 57 peroxynitrite 57 amyloid beta 57 Protein Kinase C 57 intercellular signaling 57 VEGF vascular endothelial 57 P selectin 57 small molecule inhibitors 57 intracellular signaling pathway 57 PDE4 57 lysophosphatidic acid 57 angiotensin II receptor 57 heme oxygenase 1 57 Vpu 57 NF KappaB 57 intracellular protein 57 HIF 1alpha 57 tumor vasculature 57 engineered RAP peptides 57 ACh 57 SIRT3 57 estrogen receptor alpha 57 RNA splicing 57 histone deacetylase 57 Kv#.# 57 Integrins 57 β amyloid 57 oncogenic 57 Rab5 57 porphyrins 57 coronary vasodilation 56 TGF alpha 56 alpha#beta# 56 Th2 cytokines 56 protein kinases 56 MetAP2 56 downstream effectors 56 downregulating 56 CDK inhibitor 56 histone deacetylation 56 PLA2 56 adrenoceptor 56 osteoclasts 56 Cathepsin B 56 bcl 2 56 NF kappaB activation 56 triphosphate 56 cholesterol absorption 56 ANGPTL4 56 tubulin 56 integrase enzyme 56 Src 56 AChE 56 receptor alpha 56 Vascular endothelial growth 56 selectively inhibit 56 tumor metastasis 56 oxidase 56 ubiquitination 56 adipogenic 56 HIF 1a 56 POMC neurons 56 N cadherin 56 vascular endothelial growth 56 ERK2 56 IGF IR 56 FGF receptor 56 inflammatory cytokine 56 presynaptic 56 RNase L 56 upregulation 56 glycosyltransferase 56 CDKs 56 Caspase 56 DNMT1 56 enzymatic pathway 56 XBP 1 56 beta subunit 56 gene encodes protein 56 flavin 56 amyloid peptide 56 biochemical pathway 56 connexin 56 histone deacetylase inhibitors 56 inhibiting enzymes 56 cell adhesion 56 neurotransmitter acetylcholine 56 nitric oxide NO 56 VEGF protein 56 matrix metalloproteinase 56 naturally occurring molecule 56 amino sugar 56 neuroinflammation 56 ornithine decarboxylase 56 cholesterol biosynthesis 56 BCL2 56 adenosine receptors 56 proteolytic enzymes 56 transcytosis 56 glycolipids 56 proteasomes 56 acetylcholine receptors 56 thymidylate synthase TS 56 phosphorylate 56 BRAF protein 56 micro RNA 56 tumor suppressor PTEN 56 tyrosine kinase receptor 56 prostaglandins 56 c MET 56 estrogen metabolism 56 NR2B subunit 56 MDM2 56 nicotinic acetylcholine receptor 56 druggable target 56 PGE2 56 integrin receptors 56 ectopic expression 56 peptibody 56 factor VEGF 56 misfolded 56 osteoprotegerin 56 retinoic acid receptor 56 factor PDGF 56 thymidylate synthase 56 tumor suppressor 56 RAD# [001] 56 alveolar macrophages 56 hedgehog signaling pathway 56 TGF beta signaling 56 constitutive activation 56 mTOR pathway 56 carbohydrate metabolism 56 ERa 56 Stat3 56 TGFbeta 56 HER2 neu 56 glycosylated 56 Galectin 56 lysyl oxidase 56 signal transduction cascade 56 cyclophilin D 56 histone deacetylase HDAC 56 mTOR signaling 56 potent inhibitor 56 metalloprotease 56 Rab# 56 xanthine 56 receptor mediated endocytosis 56 proteolytic enzyme 56 autoreactive T cells 56 phosphoinositide 3 56 TLR9 56 IRAK1 56 caveolin 56 neurofibromin 56 cell lysis 56 ApoA1 56 methyl D aspartate 56 cathepsin 56 cytolytic 56 hematopoiesis 56 cannabinoid receptors 56 plasmin 56 redox active 56 chemically modify 56 GABAergic 56 IKKa 56 Bcr Abl 56 cyclin dependent kinases CDKs 56 NR2B 56 mTOR signaling pathway 56 autoantigens 56 Aurora kinase 56 mitochondrial function 56 receptor PPAR 56 C1q 56 angiotensinogen 56 HuR 56 angiotensin II 56 signal transduction pathway 56 UCP1 56 fatty acid biosynthesis 56 NKG2D 56 ligases 56 biosynthetic 56 IFNg 56 LRP5 56 apoE4 56 SREBP 56 proteolysis 56 galectin 3 56 abnormal angiogenesis 56 small molecule activators 56 alpha secretase 56 cyclin dependent kinase inhibitor 56 STAT3 signaling 56 siRNA binds 56 tumor suppressor proteins 56 ERK phosphorylation 56 tubulin polymerization 56 ribonuclease 56 receptor molecule 56 PTEN protein 56 Overexpression 56 excitatory neurotransmitter 56 CCN2 56 alpha synuclein gene 56 inhibit VEGF 56 dynamin 56 phosphodiesterases 56 inhibitory effects 56 intracellular pathways 56 allergic inflammation 56 MUC1 56 NF kappaB pathway 56 DGAT1 56 dendritic spine 56 beta adrenergic receptors 56 inhibit tumor 56 histone deacetylases HDACs 56 neuronal dysfunction 56 OCT4 56 phagocyte 56 ligand TRAIL 56 detoxification enzymes 56 lipases 56 factor PlGF 56 SWI SNF 56 Prolactin 56 NAD + 56 tyrosine kinases 56 neuronal signaling 56 H#K# methylation 56 cyclin dependent kinase 56 EGFR protein 56 E cadherin 56 effector functions 56 PI3K signaling 56 metalloproteinases 56 specific lectin receptors 56 Wnt 56 TORC2 56 nicotinic receptor 56 hypermethylation 56 inducing apoptosis 56 carbohydrate polymer 56 JAK3 56 anionic backbone 56 GNAQ 55 IFN γ 55 cystic fibrosis transmembrane conductance 55 DNA hypermethylation 55 selectively inhibiting 55 tau phosphorylation 55 AMPA receptor 55 insulin sensitizing 55 androgen receptor signaling 55 P#X# receptor 55 renin angiotensin system 55 upregulates 55 PKC inhibitor 55 lipid peroxides 55 Arp2 3 55 anti inflammatory cytokine 55 progerin 55 PDGF receptor 55 mediating pathological inflammation 55 SUMOylation 55 angiotensin 55 endogenous ligands 55 RIP1 55 CCL# 55 glycoproteins 55 aromatase enzyme 55 ALDH2 55 BCL6 gene 55 glial cell 55 NOTCH1 55 HIV reverse transcriptase 55 endocannabinoids 55 TGF Beta 55 TRPV3 55 chemically modifying 55 elastase 55 WWP2 55 Fc receptor 55 M1 muscarinic 55 thrombin receptor 55 neuroblastoma cells 55 apoptosis pathways 55 avidin 55 lysosomal enzyme 55 Cx# [001] 55 pathophysiological effects 55 Notch signaling pathway 55 pre mRNA splicing 55 vascular permeability 55 related apoptosis inducing 55 Mcl 1 55 vasodilatation 55 hyperactivation 55 CD#L 55 integrin receptor