downregulating

Related by string. downregulated * * *

Related by context. All words. (Click for frequent words.) 72 Akt signaling 72 mitogen activated protein kinase 72 IL 1β 71 IFN γ 71 mitogen activated protein kinases 71 ERK1 2 71 antibody mediated 70 leukocyte adhesion 70 TNFalpha 70 RAS RAF MEK 70 Treg cell 70 MAP kinase 70 aberrantly activated 70 upregulates 70 c MYC 69 FGFs 69 p# MAPK 69 Upregulation 69 NF kappaB activation 69 TGF b 69 serine threonine 69 neurite outgrowth 69 serine proteases 69 upregulating 69 androgen receptor AR 69 fibrogenesis 69 excitotoxic 69 renal fibrosis 69 pathophysiological effects 68 mucosal immune responses 68 γ secretase 68 CagA 68 p# activation 68 erythropoiesis 68 selectively inhibited 68 eotaxin 68 adrenoceptor 68 acetylcholine receptor 68 β catenin 68 adipogenic 68 proapoptotic 68 proteoglycan 68 Th2 cytokines 68 IL 1ß 68 SSc 68 hyperactivation 68 mitogenic 68 downregulates 68 Hedgehog signaling 68 ErbB4 68 cholesterol homeostasis 68 cyclic adenosine monophosphate cAMP 68 autocrine 68 nAChR 68 cAMP signaling 68 cathepsins 68 Clusterin 68 factor HGF 68 cytokine signaling 68 potent inducer 67 prostaglandin synthesis 67 overactivation 67 astrocytic 67 MAP kinases 67 effector cells 67 steroidogenic 67 cyclooxygenase COX 67 c myc gene 67 Th1 cells 67 isotypes 67 humoral antibody 67 ErbB receptors 67 cytoprotective 67 fibrin deposition 67 inducible nitric oxide synthase 67 basophils 67 apoptosis induced 67 ADAMTS# 67 EGF receptor 67 IL #p# 67 Rap1 67 cell adhesion molecule 67 FasL 67 ectopic expression 67 glucokinase 67 STAT1 67 LRP5 67 Jhdm2a 67 proto oncogene 67 prostaglandin E2 PGE2 67 nAChRs 67 microtubule dynamics 67 immunopathology 67 IKK2 67 activate p# 67 interleukin IL -# 67 IgG4 67 deacetylation 67 cyclic AMP cAMP 67 5 HT2A receptor 67 Kinoid 67 HIF 1alpha 67 gastric carcinomas 67 catenin 67 NADPH oxidase 67 antiapoptotic 67 HDAC2 67 adaptive immunity 67 MMP2 67 mediated inhibition 67 ornithine decarboxylase 66 epithelial tumors 66 NF KB 66 dephosphorylation 66 kidney urologic 66 oncogenic signaling 66 tumoral 66 HER2 neu 66 adenylate cyclase 66 lymphoid organs 66 tryptase 66 RUNX3 66 apoptotic pathway 66 pharmacological inhibition 66 thyroid peroxidase 66 c MET 66 TTR gene 66 ERK activation 66 NKG2D 66 Leydig cell 66 sortilin 66 Src kinase 66 NFκB 66 protein tyrosine phosphatase 1B 66 keratinocyte 66 iNOS 66 heme oxygenase 66 leukocyte recruitment 66 ACh 66 autophagic 66 ERK signaling 66 Th1 type 66 TGF ß 66 overactivated 66 IL #R 66 demethylation 66 intestinal epithelium 66 coagulation cascade 66 #HT#A 66 ADAM# 66 synovial cells 66 hypoxia inducible factor 66 cyclooxygenase 2 66 IRE1 66 P cadherin 66 CB2 receptor 66 constitutively expressed 66 isoenzyme 66 platelet activation 66 PDGFR 66 V#F mutation 66 myopathies 66 nNOS 66 ERK pathway 66 elastase 66 signaling cascades 66 cisplatin resistant 66 HIF 1a 66 glucocorticoid receptors 66 mediated apoptosis 66 selective inhibition 66 somatostatin 66 p# alpha [001] 66 phosphoprotein 66 pleiotropic 66 mevalonate 66 Wnt signaling pathway 66 AT1R 66 Oncogenic 66 JAK2 enzyme 66 eicosanoid 66 histone deacetylases 66 mitogen activated protein 66 S6K 66 costimulation 66 Neuropeptide Y 66 pRb 66 ERalpha 65 mda 7 65 PTHrP 65 DNMT1 65 myeloperoxidase 65 neuronal apoptosis 65 TrkA 65 NFkappaB 65 regulated kinase ERK 65 IL 1beta 65 VEGF receptor 65 innate immune responses 65 paxillin 65 myofibroblast 65 Smad3 65 IL 1Ra 65 phosphatidylinositol 3 65 MAPK pathway 65 nitric oxide synthase 65 genotoxic stress 65 NKT cell 65 neurotrophic 65 oncogenic transformation 65 eNOS 65 GABAA receptors 65 IFN ß 65 apoptosis pathways 65 constitutive activation 65 intracellular bacteria 65 activin 65 c Src 65 TGF ß1 65 neuromuscular junction 65 methyl D aspartate 65 sphingolipid 65 transduce 65 cyclic nucleotide 65 interleukin IL -6 65 DNA methyltransferases 65 lytic 65 ouabain 65 CEACAM1 65 N methyl 65 protein secreted 65 hypothalamic pituitary 65 CDK5 65 HIF1 alpha 65 Overexpression 65 p# MAP kinase 65 phosphorylates 65 PGC 1α 65 Interferon gamma 65 ß catenin 65 hCG Beta 65 metalloproteinase 65 glycated 65 retinal ischemia 65 5 HT2A serotonin 65 TRAIL induced apoptosis 65 Cytotoxic T 65 cardiac fibroblasts 65 regulating gene expression 65 thromboxane A2 65 ERBB2 65 neuronal differentiation 65 Angiotensin converting enzyme 65 PAK1 65 transcriptional repressor 65 selective modulator 65 inverse agonist 65 receptor inhibitor 65 antioxidant enzymes 65 TMEM#B 65 downregulated 65 PDGF alpha receptor 65 Fc receptor 65 osteoblastic 65 TGF alpha 65 D aspartate 65 beta subunit 65 thymidylate synthase TS 65 allergic inflammation 65 RANK Ligand 65 matrix metalloproteinases MMPs 65 LPS induced 65 cytokine receptor 65 Bcl xL 65 neoplastic diseases 65 proinflammatory 65 osteoprotegerin 65 FOXO3a 65 intracellular signaling 65 inflammatory cytokine 65 mTOR mammalian target 65 mucosal immunity 65 inhibitory neurotransmitters 65 CCL# 65 induced neuronal 65 SIRT2 65 transcriptional activation 65 motor neuron degeneration 64 peroxisomal 64 immunoreactivity 64 NLRP3 64 osteoclast formation 64 dedifferentiation 64 induces apoptosis 64 microglial activation 64 Cathepsin B 64 downregulation 64 cytolytic 64 monocytes macrophages 64 colorectal carcinoma 64 Foxp3 64 acinar 64 tumor suppressor protein 64 histone deacetylation 64 prostaglandin E2 64 Macrophage 64 serine threonine kinase 64 AhR 64 TGF beta signaling 64 mesenchymal cell 64 phosphate S1P 64 Protein Kinase C 64 glutamic acid decarboxylase 64 interleukin 1beta 64 HepG2 cells 64 homodimers 64 hypothalamic pituitary adrenal axis 64 Oxidative damage 64 HIF 1α 64 noradrenergic 64 IL6 64 GLI1 64 CD#c 64 extracellular signal 64 BCL2 64 ChR2 64 vasodilatation 64 mu receptor 64 effector function 64 aberrant activation 64 melanocyte 64 alpha subunit 64 #T# L1 64 tensin homolog 64 VEGF expression 64 beta1 integrin 64 antiviral cytokines 64 Hh pathway 64 HCV replication 64 RKIP 64 FGFR1 64 COX2 64 podocyte 64 immuno modulatory 64 aldose reductase 64 suppressor cells 64 fibrotic disease 64 gastric carcinoma 64 TXNIP 64 NKX#.# 64 GSK3B 64 PTP 1B 64 misregulation 64 PKC inhibitors 64 abnormal angiogenesis 64 costimulatory 64 tau phosphorylation 64 vascular endothelial cells 64 β1 64 alpha TNF α 64 PDGF receptor 64 CYP #A# 64 PECAM 1 64 tropomyosin 64 neuropeptide Y NPY 64 IGFBP 3 64 TNFa 64 innate immune 64 CD8 + 64 anti inflammatory cytokine 64 pancreatic endocrine 64 effector T 64 T lymphocyte 64 synaptogenesis 64 monocyte 64 membrane receptors 64 tumor suppressor PTEN 64 gastric carcinogenesis 64 effector memory 64 PC# cells 64 retinoic acid receptor 64 activated lymphocytes 64 humoral 64 CD#b 64 excitotoxicity 64 hematopoietic progenitors 64 hypoxia induced 64 TGF β 64 cytotoxic T lymphocyte 64 Factor VEGF 64 myeloid derived 64 CXCL# 64 HDAC6 64 tyrosinase 64 IRS1 64 Integrins 64 cyclooxygenase 64 airway hyper responsiveness 64 hydrolases 64 hyperalgesia 64 Wnt proteins 64 Runx2 64 intercellular adhesion molecule 64 induce apoptosis 64 CCL5 64 PPARg 64 EGFR receptor 64 fatty acid oxidation 64 hypermethylated 64 androgen dependent 64 nicotinic acetylcholine receptor 64 LRP6 64 isoenzymes 64 Th2 64 pyrimidines 64 JNK1 64 anionic backbone 64 uPAR 64 protein tyrosine kinase 64 glutamate receptors 64 PCA3 gene 64 TNF receptor 64 kappa opioid receptors 64 neuronal dysfunction 64 p# mitogen activated 64 vWF 64 c myc 64 Factor Receptor 64 casein kinase 64 JAK STAT 64 M1 macrophages 64 potent inhibitors 64 carcinoembryonic antigen 64 constitutively active 64 FGFR3 64 virulence genes 64 NMDA N 64 tyrosine kinase receptor 64 COX enzymes 64 downstream effectors 64 NF kB pathway 64 immunoregulatory 64 adipogenesis 64 lipopolysaccharide 64 VE cadherin 63 adrenocortical 63 hypersecretion 63 acyl CoA 63 adenosine diphosphate ADP 63 nutlin 3a 63 tyrosine phosphorylation 63 peroxisome 63 TNF α 63 BMP signaling 63 superantigens 63 FGFR4 63 mitogen 63 STAT3 signaling 63 uPA 63 immunomodulation 63 receptor tyrosine kinase 63 experimental autoimmune encephalomyelitis 63 upregulate 63 telomerase reverse transcriptase 63 organogenesis 63 CD8 cells 63 RIP1 63 mineralocorticoid 63 microglial 63 deacetylase 63 Rho kinase 63 monomeric 63 MAPKs 63 p# Shc 63 Tasigna prolongs 63 Flt3 63 BMP4 63 lymphoid tissues 63 M1 muscarinic 63 interleukin 1β 63 cdk5 63 EphB2 63 Lyn kinase 63 pDCs 63 osteogenic differentiation 63 Akt activation 63 thymidylate synthase 63 inhibiting enzymes 63 pro angiogenic 63 humoral immunity 63 E#F# 63 oncogenesis 63 intracellular accumulation 63 plasmacytoid dendritic cells 63 cyclin dependent kinases CDKs 63 transcriptional silencing 63 PAR1 63 Angiotensin II 63 hydroxylase 63 replicase 63 Th1 63 haematopoietic 63 motoneurons 63 Hypoxia Inducible Factor 63 Osteopontin 63 Tumor necrosis factor 63 5 HT1A receptor 63 osteoblast 63 apoptotic pathways 63 tissue fibrosis 63 osteolytic 63 proinflammatory cytokine 63 collagen deposition 63 potentiation 63 TGF beta1 63 RRM1 63 P#X# receptors 63 ligand TRAIL 63 human airway epithelial 63 autoreactive T cells 63 inhibit viral replication 63 TNFα 63 TRPV1 receptors 63 4E BP1 63 S1P 63 ERK phosphorylation 63 Androgen receptor 63 gene polymorphisms 63 transgenic rats 63 granzyme B 63 immunomodulatory effects 63 radiosensitivity 63 MCF7 63 neutrophil recruitment 63 trastuzumab resistant 63 cell adhesion molecules 63 PDGFR alpha 63 anti CD3 63 enzymatic pathways 63 molecule interleukin 63 nociceptive 63 degranulation 63 autoreactive 63 EP3 receptor 63 glioblastoma tumor 63 HIV reverse transcriptase 63 NS#/#A protease 63 transgene expression 63 hematopoiesis 63 PEDF 63 Notch signaling 63 partial agonist 63 S nitrosylation 63 aryl hydrocarbon receptor 63 myofibroblasts 63 glutamatergic 63 MAPK 63 inflammatory cytokines TNF 63 inhibitory transmitter 63 PI3K Akt 63 clonogenic 63 kinase pathway 63 pro inflammatory cytokine 63 PTEN protein 63 HER2 HER2 63 mucosal immune 63 leukemia inhibitory 63 pancreatic islet beta 63 dimeric 63 receptor subtypes 63 leukotriene pathway 63 Rb#/p# 63 bone morphogenic protein 63 neuronal signaling 63 Htt 63 pDC 63 cytokines chemokines 63 chloride secretion 63 cholesterol biosynthesis 63 granulocyte macrophage colony stimulating 63 TRPV4 63 Th2 immune 63 vimentin 63 vessel constriction 63 potent antiproliferative 63 Dysregulation 63 glial cell 63 underlying vasculopathy 63 triggers apoptosis 63 chemoresistance 63 metabolizing enzyme 63 pro inflammatory cytokines 63 humoral immune responses 63 IGFBP2 63 interferon pathway 63 interferon γ 63 downregulate 63 caveolin 1 63 histone acetylation 63 potentiating 63 LTB4 63 evolutionarily conserved 63 lactate dehydrogenase LDH 63 PTPN# 63 alpha#beta# 63 lymphangiogenesis 63 podocytes 63 Î ² 63 calcineurin 63 MT1 MMP 63 Cyclin E 63 cytokines IL 63 IGF IR 63 hepatic lipase 63 enzymatic activity 63 osteogenic 63 inhibits protein synthesis 63 p#Kip# 63 Fas ligand 63 potent stimulator 63 intracellular signal transduction 63 hyperactivated 63 monocyte chemoattractant protein 63 TGFß 63 upregulation 63 neuroinflammatory 63 polymorphonuclear 63 gluconeogenesis 63 neuron degeneration 63 Kupffer cells 63 ectodermal 63 interleukins 63 focal adhesion kinase 63 dose dependently 63 inhibitory effects 63 extracellular calcium 63 neoplastic 63 tenascin C 63 effector functions 63 tumor metastasis 63 chitinase 63 anaphase promoting complex 63 SIRT3 63 malignant phenotype 63 Treg cells 63 monocyte chemotactic protein 63 soluble TNF receptor 63 hormone secretion 63 XL# inhibits 63 oncoprotein 63 CYP#B# 63 monoclonal anti 63 paracrine 63 posttranslational modification 63 lipogenesis 63 Inappropriate activation 63 lactate dehydrogenase 63 neuronal plasticity 63 glycosylated 63 synaptic transmission 63 phosphatases 63 redox active 63 reductase 63 IAP inhibitor 63 PON1 63 ENaC 62 survivin expression 62 neurofibromin 62 neurosteroid 62 related apoptosis inducing 62 malignant transformation 62 oncomodulin 62 SETDB1 62 tumorigenicity 62 Vascular endothelial growth 62 NF κB 62 dependent cellular cytotoxicity 62 GRP# 62 neurturin 62 eIF4E 62 RANK ligand 62 Nedd4 62 Topoisomerase II 62 oligomerization 62 MEK1 62 N Myc 62 Cryptococcus neoformans 62 XP# Transported Prodrug 62 Phosphorylation 62 inhibiting COX 62 thrombospondin 62 Cx# [001] 62 muscarinic receptors 62 transthyretin 62 estrogen receptor alpha 62 matrix metalloproteases 62 vitamin D receptors 62 EGFr 62 EP1 receptor 62 leptin signaling 62 pro apoptotic 62 type glutamate receptor 62 colorectal adenocarcinoma 62 integrin alpha 4 62 ERa 62 paraneoplastic 62 NOD2 62 super oxide dismutase 62 HBV replication 62 NFkB 62 guanosine 62 Nod1 62 mononuclear 62 Selective Inhibitor 62 BMAL1 62 resistin 62 lymphoid cells 62 lymphotoxin 62 mutated K ras 62 Hcrt 62 Wnt beta catenin 62 proton pump 62 PEPCK 62 stem cell pluripotency 62 catalytic subunit 62 hematopoietic cells 62 ARNT 62 NF kappaB 62 Six3 62 cytokines interleukin 62 TGF beta pathway 62 Dystrophin 62 Leydig cells 62 phospholipase A2 62 heme oxygenase 1 62 excitatory neurotransmitter glutamate 62 functional polymorphism 62 activated microglia 62 gamma amino butyric 62 thyroid hormone receptor 62 CYP#A# enzyme 62 LRP1 62 adipokine 62 osteoclast 62 JAK#/JAK# 62 serine protease 62 SUMOylation 62 Sertoli cell 62 transcriptional regulation 62 HBx 62 epigenetic modification 62 EGFR pathway 62 microvascular endothelial cells 62 cholecystokinin CCK 62 CaMKII 62 proinflammatory cytokines 62 EGFR tyrosine kinase inhibitor 62 selectively inhibiting 62 genus Plasmodium 62 lipoxygenase 62 acetylcholinesterase 62 intercellular signaling 62 lung epithelium 62 mitochondrial respiration 62 Src kinases 62 proinflammatory mediators 62 Adrenergic 62 neuronal nitric oxide synthase 62 tyrosine hydroxylase 62 kinase gene 62 acid GABA 62 integrin activation 62 anti apoptotic proteins 62 CCR7 62 #ß HSD1 62 intestinal mucosal 62 endogenous cannabinoids 62 potent inhibition 62 calcitonin gene related 62 glutamatergic neurons 62 subcellular compartments 62 coiled coil domain 62 proteolytic 62 chondrocyte 62 siRNA knockdown 62 receptor mediated 62 axon guidance 62 GLUT1 62 receptor alpha 62 aminobutyric acid 62 CYT# potent vascular disrupting 62 CPEB 62 intimal hyperplasia 62 mycobacterial 62 neurogenic inflammation 62 glutamyl 62 LDL receptor 62 PI3K signaling pathway 62 Ribavirin causes 62 hypomethylation 62 potently inhibited 62 retinoid X 62 effector molecules 62 Nampt 62 melanocyte stimulating hormone 62 renin angiotensin aldosterone 62 p#NTR 62 invading pathogen 62 lung fibrosis 62 polyamine 62 proximal tubular 62 mutant huntingtin protein 62 pyramidal cells 62 coronary vasodilation 62 NKT cells 62 mTOR pathway 62 mitotic progression 62 colonic mucosa 62 #beta HSD1 62 ERK5 62 hepatocellular 62 adipokines 62 Hsp# [001] 62 PPARγ 62 D aspartate NMDA receptor 62 amyloid formation 62 JAK STAT signaling 62 steroidogenesis 62 PKC isoforms 62 GABRA2 62 interstitium 62 catalase 62 SMAD4 62 poly ADP ribose polymerase 62 hip osteonecrosis avascular 62 epithelial cells lining 62 CCR9 62 neurotransmitter GABA 62 cardiolipin 62 leptin receptor 62 basic fibroblast 62 glycolipids 62 receptor gamma 62 VEGF induced 62 neurofilament 62 TCF#L# 62 dorsomedial 62 NR#A# 62 E selectin 62 dorsolateral 62 Thyroid hormone 62 axonal damage 62 regulated kinase 62 beta adrenergic receptors 62 TGFb 62 cellular organelles 62 thyrotropin 62 HbF 62 STAT4 62 CD1d 62 protein tyrosine phosphatases 62 neurotrophic factors 62 premalignant 62 chlamydial 62 immunostimulatory 62 EBV infection 62 Tissue Factor 62 neuroinflammation 62 habenula 62 Notch1 62 Wnts 62 Rho GTPases 62 endocrine tumors 62 bacterial virulence 62 Fc receptors 62 regulates gene expression 62 virulence determinants 62 p#INK#a 62 cytidine 62 epigenetic alterations 62 anterior cortex 62 NO synthase 62 thymidine kinase 62 erythroid 62 EF Tu 62 CD# expression [001] 62 myelofibrosis polycythemia vera 62 superoxide dismutase 62 endothelial nitric oxide synthase 62 HER2 expression 62 RAS RAF MEK ERK 62 sGC 62 amyloid deposition 62 K + ATPase 62 TrkB 62 PPAR γ 62 cytokine 62 #ME# 62 RNA silencing 62 myoclonus 62 p# deficient 62 5 HT1A 62 CHD7 62 transcriptional activity 62 c Fos 62 glucocorticoid receptor 62 PKC inhibitor 62 prostatic tissue 62 hypermethylation 62 metabolizing enzymes 62 beta arrestin 62 histone deacetylase HDAC 62 ZNF# 62 Fibroblast Growth Factor Receptor 62 lysosomal 62 metastatic lymph nodes 62 mRNA expression 62 norepinephrine reuptake inhibition 62 Propionibacterium acnes 62 protein actin 62 agonists antagonists 62 spermidine 62 transactivation 62 MEF2A 62 IKKß 62 branching morphogenesis 62 FKBP# 62 antiproliferative effects 62 BRAF V#E 61 pathogenetic 61 Smad4 61 afferents 61 dihydrofolate reductase 61 antiproliferative 61 IFN g 61 potent anti angiogenic 61 beta. 61 leukocyte infiltration 61 alkaline phosphatase ALP 61 tumor necrosis 61 LPA1 receptor 61 cortical excitability 61 HLA DR4 immune 61 chemotactic 61 E3 ubiquitin ligase 61 diphosphate 61 pharmacologic approaches 61 VEGFR1 61 thymic 61 raphe 61 endoplasmic reticulum stress 61 alpha2 61 cofilin 61 NF kappa B 61 synthase TS 61 PPAR peroxisome proliferator activated 61 intracellular protein 61 mucociliary clearance 61 endothelial activation 61 fibrillin 1 61 collagen synthesis 61 glucagon receptor 61 airway hyperresponsiveness 61 mediated immunity 61 PI3 kinase 61 toxic beta amyloid 61 CYP#A# CYP#D# 61 acetylcholinesterase AChE 61 endotoxemia 61 proteinases 61 peripheral tissues 61 HDAC3 61 receptor activation 61 glomerular 61 Nkx#.# 61 oxidases 61 tyrosine kinase 61 glycolytic 61 P selectin 61 TORC2 61 nicotinic 61 CXCR2 61 cytokine interleukin 61 Y2 receptor 61 5 lipoxygenase 61 gonadotrophin releasing hormone 61 detoxify carcinogens 61 GPI anchored 61 inhibitory effect 61 DNA hypermethylation 61 Mcl 1 61 TNFR 61 FOXO 61 calpain 61 neutrophilic 61 FGFR2 61 prostanoid 61 multinucleated 61 NF kB signaling

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