Related by context. All words. (Click for frequent words.) 70 rFVIIa 69 AST ALT 69 divalproex sodium 69 clevidipine 69 oral anticoagulant therapy 69 guanfacine 69 vidofludimus 69 haematologic 69 deferiprone 69 intravascular hemolysis 68 relapsed MM 68 Hydroxyurea 68 inhaled iloprost 68 IOP lowering 68 Cloretazine 68 NATRECOR ® 68 coadministration 68 hematologic parameters 68 atrioventricular block 67 CHAMPION PCI 67 AGHD 67 thrombocytopenic 67 riociguat 67 MYCAMINE 67 inhaled treprostinil 67 MERLIN TIMI 67 sitaxsentan 67 miglustat 67 ATACAND 67 EDARBI 67 anagrelide 67 serum calcium levels 67 β blockers 67 canakinumab 66 FXIII 66 calcineurin inhibitor 66 ULORIC 66 fluvastatin 66 MAGE A3 ASCI 66 STRIDE PD 66 Insulin detemir 66 trastuzumab Herceptin ® 66 BrachySil TM 66 teriflunomide 66 NATRECOR R 66 myopathy rhabdomyolysis 66 recurrent glioblastoma multiforme 66 cardiac repolarization 66 hsCRP levels 66 GAMMAGARD 66 clomipramine 66 ziconotide 66 brivaracetam 66 paricalcitol 66 antiangiogenic therapy 66 antioxidant supplementation 66 tumor necrosis 66 oral anticoagulation 66 EXJADE 66 NPH insulin 66 macrolide antibiotic 66 nephrotoxicity 66 USL# 66 insulin detemir 66 VAPRISOL 66 liver histology 66 genotypic resistance 66 PASI scores 66 pyridostigmine 66 phase IIb trial 66 symptomatic VTE 65 angiographic outcomes 65 galiximab 65 DAPT 65 BARACLUDE ® 65 sipuleucel T 65 pamidronate 65 plasminogen activators 65 serum cortisol 65 prucalopride 65 CIMZIA ™ 65 fosbretabulin 65 nitrofurantoin 65 TYGACIL 65 Keppra XR 65 dexmedetomidine 65 PROMACTA 65 KAPIDEX 65 nicardipine 65 lipid lowering agents 65 oxcarbazepine 65 CANCIDAS 65 cinacalcet 65 levodopa carbidopa 65 ritonavir boosted 65 serum phosphate 65 antiepileptics 65 corticosteroid dexamethasone 65 treprostinil 65 serum lipid levels 65 OHR/AVR# 65 FOSRENOL ® 65 antidiabetic drug 65 morphometric vertebral fractures 65 denileukin diftitox 65 epoetin alpha 65 serum phosphate levels 65 Teriflunomide 65 Triapine R 65 antimuscarinic 65 Hepatotoxicity 65 dose cohort 65 alfuzosin 65 systemic bioavailability 65 systemic hypotension 65 HSCT 65 budesonide foam 65 tolterodine 65 IMPACT DCM 65 renal biopsy 65 REMINYL ® 65 PNH patients 65 colorectal adenoma 65 Natalizumab 65 SCIg 65 Tarceva TM 65 candidemia 65 HbA 1c levels 65 salmeterol fluticasone 65 plasma pharmacokinetics 65 APTIVUS r 65 bovine thrombin 65 PRADAXA 65 forodesine 65 Elitek 64 ORENCIA R 64 venous thromboembolic disease 64 Dacogen injection 64 dose proportionality 64 tegaserod 64 gallium nitrate 64 antiarrhythmic drugs 64 clonidine hydrochloride 64 RAPAFLO R 64 intermittent dosing 64 candesartan cilexetil 64 antithrombotic therapy 64 Decitabine 64 colorectal liver metastases 64 tolvaptan 64 hemodilution 64 INVEGA ® 64 ZOLINZA 64 pouchitis 64 certolizumab 64 hyperphenylalaninemia HPA due 64 pimecrolimus 64 desvenlafaxine succinate 64 LCP Tacro TM 64 deep venous thromboses 64 glycosylated hemoglobin levels 64 erythropoietic 64 EFFEXOR XR 64 symptomatic intracranial 64 MAS XR 64 Vimpat R 64 lanthanum carbonate 64 Xelox 64 mesalamine granules 64 tipranavir 64 PAOD 64 PROCRIT ® 64 antiplatelet therapies 64 atazanavir ritonavir 64 immunomodulatory therapy 64 DLTs 64 hMG 64 liposomal amphotericin B 64 guanfacine extended release 64 bolus dose 64 AGILECT R 64 IFN beta 64 LHRH agonists 64 Degarelix 64 HoFH 64 oral rivaroxaban 64 BENICAR HCT 64 pioglitazone HCl 64 MULTAQ 64 glomerular filtration 64 MYLOTARG 64 hepatorenal syndrome 64 posaconazole 64 serum urate 64 renoprotective 64 Traficet EN 64 CARE HF 64 postprocedure 64 oral diclofenac 64 pentoxifylline 64 paclitaxel Taxol R 64 Insulin PH# 64 ADHF 64 diabetic polyneuropathy 64 opioid analgesia 64 nimodipine 64 prospective multicenter study 64 gliclazide 64 glycosylated hemoglobin HbA1c 64 TMS Therapy 64 multidose 64 Vidaza azacitidine 64 QTc prolongation 64 aminotransferases 64 dosing frequency 64 pharmacokinetic PK study 64 antimicrobial prophylaxis 64 efalizumab 64 solifenacin 64 antibiotic prophylaxis 64 PREZISTA r 64 hematological toxicity 64 intravenous bisphosphonates 64 doxorubicin docetaxel 64 elacytarabine 64 inhaled budesonide 64 esophageal candidiasis 64 dosage regimens 64 mesilate 64 pharmacodynamic parameters 64 lenalidomide dexamethasone 64 ximelagatran 64 octreotide 64 ADAGIO study 64 AZILECT ® 64 invasive candidiasis 64 Aprotinin 64 hepatic encephalopathy HE 64 antiplatelet drugs 64 glycated hemoglobin levels 64 Zavesca R 64 oncologic outcomes 64 allogeneic HSCT 64 GOUT 64 macroalbuminuria 64 inotropes 64 DACH platinum 64 intravenous diuretics 64 REVLIMID lenalidomide 64 clazosentan 64 antithrombotic 64 pegaptanib 63 BEXXAR Therapeutic Regimen 63 perioperatively 63 levetiracetam 63 myocardial necrosis 63 intravitreal injections 63 ibandronate 63 serum urate levels 63 argatroban 63 bosentan 63 MS relapses 63 pharmacokinetic interactions 63 ALT flares 63 Dacogen decitabine 63 ARIXTRA 63 cytopenias 63 Kaplan Meier estimate 63 metastatic malignant 63 salmeterol HFA MDI 63 Alequel 63 pharmacokinetic characteristics 63 dose atorvastatin 63 thromboembolic disease 63 selective modulator 63 FIRMAGON 63 NAbs 63 antibody titer 63 hemodialysis patients 63 corticosteroid dose 63 Febrile neutropenia 63 DOXIL 63 vivo potency 63 sunitinib malate 63 hepatic enzymes 63 Eltrombopag 63 caspofungin 63 intracranial hemorrhage ICH 63 rhGH 63 #mg/day [001] 63 palivizumab 63 vaso occlusive crisis 63 Infusion Reactions Severe 63 thrombolytic agents 63 antiemetics 63 INFERGEN 63 subcutaneous dosing 63 intracerebral haemorrhage 63 ruboxistaurin 63 intravenous dosing 63 thalidomide Thalomid 63 oral FTY# 63 Zemplar Capsules 63 Myozyme alglucosidase alfa 63 antiarrhythmic drug 63 thrombotic complications 63 fibrinolysis 63 Tracleer R 63 RE LY ® 63 variceal bleeding 63 immunosuppressive regimen 63 virologic response 63 neutrophil counts 63 GLP1 agonist 63 chronic thromboembolic pulmonary 63 platelet inhibition 63 β blocker 63 randomized Phase IIb 63 mg/m2 dose 63 hypotensive 63 lipid lowering therapy 63 Gamunex C 63 histrelin 63 basal bolus regimen 63 PRISTIQ 63 serum creatinine levels 63 VP# [004] 63 elevated IOP 63 VIIBRYD 63 ritonavir boosted protease inhibitor 63 Raptiva ® 63 XL# SAR# 63 labetalol 63 hyperprolactinemia 63 antiplatelet medication 63 intravenous IV infusion 63 Fibrillex TM 63 acute mania 63 hematological parameters 63 adalimumab Humira 63 intravesical therapy 63 Prograf R 63 Candesartan 63 Nebulized 63 Betaferon R 63 serum HBV DNA 63 Hypotension 63 Kepivance 63 neutropenic patients 63 G CSFs 63 therapeutic regimens 63 intravesical 63 anticholinergic agents 63 steroid dexamethasone 63 virological response 63 chest radiographs 63 HIV HCV coinfected 63 Lamotrigine 63 CsA 63 hyperoxaluria 63 pretransplant 63 NIASPAN 63 Pemetrexed 63 alefacept 63 protease inhibitor PI 63 randomized multicenter Phase III 63 herpetic keratitis 63 AZOR 63 Teriparatide 63 postprandial glycemia 63 biliary tract cancer 63 micafungin 63 TMP SMX 63 analgesic medications 63 quetiapine XR 63 pharmacodynamic PD 63 cerebral vasospasm 63 docetaxel Taxotere ® 63 dorzolamide 63 fluticasone furoate 63 antihypertensive therapy 63 cranial irradiation 63 plasma renin activity 63 transaminase elevations 63 PROCHYMAL 63 corticosteroid therapy 63 neuroleptic 63 Targretin capsules 63 liver transaminases 63 Intra arterial 63 HER2 overexpression 63 biologic DMARD 63 Mycophenolate Mofetil 63 Effexor venlafaxine 63 RISPERDAL ® 63 randomized multicenter trial 63 TPV r 63 Evoltra ® 63 Tumor Response 63 SGPT 63 KAPVAY ™ 63 serum phosphorous 63 triglyceride concentrations 63 ORENCIA ® 63 demonstrated antitumor activity 63 rtPA 63 phase IIIb 63 parkinsonian symptoms 63 methotrexate therapy 63 Phase Ib study 63 pharmacokinetic interaction 63 adrenal suppression 63 alteplase 63 F FDG PET 63 rALLy 63 dopaminergic therapy 63 intestinal permeability 63 VADT 63 mild hepatic impairment 63 Postoperative complications 63 aripiprazole Abilify 63 INTEGRILIN 63 mycophenolate mofetil MMF 62 indiplon capsules 62 PSA nadir 62 lipid parameters 62 gastrointestinal stromal tumors GIST 62 dopamine partial agonist 62 BeneFIX 62 Femara letrozole 62 SPRYCEL ® 62 abacavir Ziagen 62 Akt activation 62 Cleviprex TM clevidipine 62 calcineurin inhibitors 62 glatiramer 62 rilonacept 62 DCCR 62 HeFH 62 Non inferiority 62 fibrinolytic therapy 62 quetiapine Seroquel 62 intracranial hypertension 62 LANTUS ® 62 radiographic outcomes 62 hepatic fibrosis 62 ularitide 62 intravenous cyclophosphamide 62 hematologic toxicity 62 lomitapide 62 cefepime 62 ZACTIMA 62 recurrent venous thromboembolism 62 ancrod 62 GI motility 62 INTERCEPT platelets 62 systemic corticosteroid 62 lactate dehydrogenase LDH 62 eplerenone 62 thrombolytic agent 62 GnRH agonist 62 ß blockers 62 aldosterone antagonist 62 Helicobacter pylori eradication 62 timepoint 62 zotarolimus 62 neurologic progression 62 keloid scarring 62 efficacy endpoint 62 CLORETAZINE TM VNP#M 62 antidiabetic medications 62 verteporfin 62 posttreatment 62 parasitemia 62 AMEVIVE 62 opioid dependent 62 thrombolytics 62 CIMZIA TM certolizumab pegol 62 severe hypersensitivity reactions 62 injectable formulations 62 Certolizumab pegol 62 femoral neck fracture 62 oxypurinol 62 RSD# oral 62 Privigen 62 CIMZIA TM 62 menadione 62 smoldering multiple myeloma 62 elotuzumab 62 thorough QT 62 thromboprophylaxis 62 RezularTM 62 elevated LDH 62 EGFRIs 62 thiazide diuretic 62 serum uric acid 62 H. pylori eradication 62 retrospective cohort 62 subcutaneously administered 62 postintervention 62 carotid endarterectomy CEA 62 sargramostim 62 pegfilgrastim 62 TLK# 62 dose melphalan 62 diabetic kidney 62 cystoid macular edema 62 blood glucose concentrations 62 tipranavir r 62 Losartan 62 Doxil ® 62 myeloproliferative diseases 62 PREVENT IV 62 RE LY trial 62 urinary N telopeptide 62 prodromal symptoms 62 deferasirox 62 pain palliation 62 pimecrolimus cream 62 CYPHER R Sirolimus eluting 62 hypoperfusion 62 OAB symptoms 62 MGd 62 APTIVUS 62 hA# 62 aldosterone antagonists 62 TYSABRI natalizumab 62 prospectively stratified 62 romiplostim 62 undetectable HBV DNA 62 eosinophilia 62 warfarin therapy 62 oxymorphone ER 62 Enzastaurin 62 oral antidiabetic medication 62 sevelamer 62 exogenous insulin 62 CYP#D# inhibitor 62 Heavy menstrual bleeding 62 decitabine 62 postoperative morbidity 62 RAPTIVA 62 adrenal insufficiency 62 hepatic function 62 anti androgen 62 CAELYX 62 cTnI 62 somatostatin analog 62 blood Phe levels 62 COPD exacerbations 62 eosinophilic asthma 62 CALGB # [002] 62 ACAPODENE 62 reinfarction 62 timepoints 62 alanine aminotransferase ALT 62 irbesartan 62 probiotic supplementation 62 homocysteine concentrations 62 Danazol 62 Azedra 62 receptor tyrosine kinase inhibitor 62 malignant ascites 62 DEXILANT 62 ICD therapy 62 Renal dysfunction 62 uricase 62 glomerular 62 icatibant 62 proton pump inhibitor PPI 62 Posaconazole 62 infliximab Remicade 62 C1 INH 62 preclinical pharmacokinetic 62 intratympanic 62 radiochemotherapy 62 liposome formulation 62 dose Iluvien 62 AVERROES 62 Meta analyzes 62 chemotherapeutic regimen 62 octreotide LAR 62 serum aminotransferase levels 62 Subgroup analysis 62 rt PA 62 ISTODAX 62 ovarian suppression 62 #I TM# 62 INCB# [001] 62 prospective nonrandomized 62 buprenorphine naloxone 62 GH deficiency 62 rALLy trial 62 invasive aspergillosis 62 Aplidin 62 acamprosate calcium 62 carotid artery stenting CAS 62 fulvestrant 62 dexanabinol 62 Advagraf 62 ALGRX 62 QT QTc 62 eliglustat tartrate 62 Procoralan 62 Adverse effects 62 BAL# [002] 62 eszopiclone 62 clinical pharmacology studies 62 Serious adverse reactions 62 lipid elevations 62 detemir 62 tiagabine 62 QD dosing 62 alanine aminotransferase 62 papillary renal cell carcinoma 62 Gabapentin GR 62 Myelodysplastic Syndrome MDS 62 crizotinib PF # 62 subcutaneous immunoglobulin 62 Eligen R B# 62 tigecycline 62 relapsing remitting MS RRMS 62 dimeglumine 62 PEARL SC 62 TORISEL 62 prazosin 62 elevated ALT 62 cannabinor 62 metaanalysis 62 QTc intervals 62 CAPHOSOL 62 complete cytogenetic response 62 NNT = 62 clinically meaningful efficacy 62 APTIVUS R 62 plasma cortisol 62 transthoracic 62 Vaprisol 62 vernakalant hydrochloride 62 milrinone 62 direct thrombin inhibitors 62 potent antiretroviral therapy 62 adefovir dipivoxil 62 platelet reactivity 62 FDG PET imaging 62 APRISO 62 drug eluting stent implantation 62 Aptivus ® 62 Phase III randomized controlled 62 mg/m2 cohort 62 cobiprostone 62 exploratory endpoints 62 colesevelam HCl 62 gross hematuria 62 aspartate aminotransferase AST 62 pegylated liposomal doxorubicin 62 Ventavis ® 62 sequestered naltrexone 62 interferon ribavirin 62 thyrotropin 62 primary hyperparathyroidism 62 BPS IC 62 preserved ejection fraction 62 davunetide intranasal AL 62 concurrent chemoradiation 62 intensive lipid lowering 62 BoNTA 62 pharmacokinetic PK profile 62 EMBEDA ™ 62 artery stenosis 62 teduglutide 62 antibiotic regimens 62 concomitant AEDs 62 fosamprenavir 62 SNT MC# 62 IPAH 62 RoACTEMRA 62 Abciximab 62 topical NSAIDs 62 lumiliximab 62 REYATAZ R 62 patientswith 62 HMG CoA reductase inhibitors 62 renal toxicity 62 clinically meaningful improvements 62 Abilify aripiprazole 62 multicenter trials 62 inotropic 62 clobazam 62 Valdoxan 62 NeuroStar TMS Therapy 62 myelodysplastic myeloproliferative diseases 62 lanreotide 62 lactulose 62 bladder carcinoma 62 T1DM 62 serum concentrations 62 null responder 62 urolithiasis 62 antiretroviral naïve 62 immunomodulation 62 insulin glulisine 62 TNF alpha inhibitor 62 TREDAPTIVE 62 DDP# 62 Fabry Disease 61 r hGH 61 lipid lowering therapies 61 EVIZON 61 ELACYT 61 somatostatin analogs 61 metabolic parameters 61 antitumor efficacy 61 omega interferon 61 tolterodine ER 61 GnRH agonists 61 grade cervical dysplasia 61 hemoglobin A1c levels 61 placebo controlled clinical trials 61 prochlorperazine 61 induce orthostatic hypotension 61 haematological 61 PROSTVAC TM 61 aspartate aminotransferase 61 paclitaxel eluting stents 61 SYN# 61 onset diabetes mellitus 61 combination antiretroviral therapy 61 Warfarin Coumadin 61 RRMS patients 61 Carbamazepine 61 myocardial reperfusion 61 antidepressants SSRIs 61 platelet inhibitor 61 antiresorptive 61 atypical hemolytic uremic syndrome 61 epoprostenol 61 antidiabetic medication 61 AA Amyloidosis 61 L PPDS 61 moderate hepatic impairment 61 antiretroviral naive 61 ARCOXIA 61 postoperative AF 61 Cimzia TM 61 CellCept mycophenolate mofetil 61 Retreatment 61 chemoradiation therapy 61 hepatotoxic 61 ganciclovir 61 LYSTEDA 61 Subgroup analyzes 61 nadolol 61 griseofulvin 61 clodronate 61 tinzaparin 61 extramedullary 61 Fulvestrant 61 strontium ranelate 61 Desferal 61 hyperalgesia 61 transaminase levels 61 chronic GVHD 61 liver metastasis 61 solithromycin 61 gastrointestinal perforation 61 endothelial activation 61 hour bronchodilation 61 disease progression TTP 61 everolimus eluting stents 61 rituximab Rituxan 61 repolarization 61 intracoronary 61 prospectively defined 61 YONDELIS 61 idraparinux 61 SEROQUEL R 61 prolactin levels 61 bezafibrate 61 Solorel 61 pharmacodynamic properties 61 Topiramate 61 relapsed ALL 61 ACOMPLIA R 61 severe gastroparesis 61 transdermal estrogen 61 postoperative mortality 61 sonographically guided 61 tasocitinib 61 GLIADEL R Wafer 61 Inhaled nitric oxide 61 unresectable tumors 61 hepatic cirrhosis 61 choroidal vasculopathy 61 scintigraphic 61 LHRH antagonists 61 flutamide 61 antiandrogens 61 olanzapine LAI 61 analgesic efficacy 61 Lubiprostone 61 Phase IIIb clinical 61 macrovascular events 61 dalteparin 61 haloperidol Haldol 61 daily subcutaneous injections 61 motilin 61 Relapsing Remitting Multiple Sclerosis 61 DMSA 61 Aloxi injection 61 curative resection 61 Patency 61 lymphocyte counts 61 visilizumab 61 virological suppression 61 aripiprazole 61 tipranavir ritonavir 61 pharmacologic therapies 61 empiric treatment 61 Phase 1a clinical 61 recurrent herpes labialis 61 virologic breakthrough 61 d4T stavudine Zerit 61 hypofractionated radiation 61 serum bicarbonate 61 metaplasia 61 dose titration 61 CTAP# Capsules 61 pharmacologic treatments 61 DVT prophylaxis 61 bronchodilation 61 ON #.Na 61 peak plasma concentrations 61 parathyroid hormone PTH 61 CONCERTA 61 Azacitidine 61 Androxal TM 61 elevated creatinine 61 diabetic gastroparesis 61 galantamine 61 Nesiritide 61 methylnaltrexone 61 Cipralex ® 61 trospium 61 latanoprost 61 maximal doses 61 rosuvastatin #mg 61 liposomal formulation 61 wilate ® 61 anticonvulsant medication 61 #beta estradiol 61 dysmenorrhoea 61 overt nephropathy 61 Focalin XR 61 vasoactive 61 prospectively enrolled 61 pharmacokinetic parameters 61 antiangiogenic agent 61 Dasatinib 61 CLL SLL 61 tapentadol ER 61 PSMA ADC 61 chronic idiopathic thrombocytopenic purpura 61 Neulasta ® 61 FAMPYRA 61 potentially hepatotoxic 61 Tacrolimus 61 KRAS status 61 Increlex R 61 ranolazine 61 conventional DMARDs 61 TNF antagonist 61 hypophosphatemia 61 docetaxel chemotherapy 61 prostate cancer CaP 61 systemic corticosteroids 61 relapsed AML 61 Nocturia 61 Perforomist ™ Inhalation Solution 61 ZD# [001] 61 Fibrillex 61 mycophenolate mofetil 61 serum IgG 61 granisetron 61 ocular disorders 61 CLARITY study 61 elective PCI 61 azacytidine 61 CINQUIL 61 sublingual tablets 61 rotigotine transdermal patch 61 Androgel R 61 chronic hemodialysis 61 resected pancreatic cancer 61 mecamylamine 61 Thalomid ® 61 edifoligide 61 HAART regimens 61 concomitant medications 61 HyQ 61 constipation OIC 61 MitraClip device 61 alvespimycin 61 venlafaxine Effexor 61 PDE4 inhibitors 61 tumorigenicity 61 titrated glipizide 61 paroxetine Paxil 61 visceral metastases 61 carotid artery stent 61 beta blocker therapy 61 oral ibandronate 61 EDEMA3 trial 61 hypercholesterolaemia 61 cediranib 61 mixed hyperlipidemia 61 HQK 61 androgen suppression 61 trials RCTs 61 nonrandomized 61 plasma triglycerides 61 serum lactate 61 VTE prophylaxis 61 LOVENOX R 61 Gattex 61 Capesaris 61 HBV infections 61 TEMODAL 61 Virulizin ® 61 Removab 61 diabetic neuropathic pain 61 hemodynamically significant 61 mRCC 61 CPAP adherence 61 atherosclerosis regression 61 intranasal formulation 61 BCR ABL inhibitor 61 surrogate markers 61 parathyroidectomy 61 elevated serum creatinine 61 adult chronic ITP 61 troponins 61 postsurgical pain 61 ONTAK 61 cysteamine bitartrate 61 Temsirolimus 61 pediatric acute lymphoblastic 61 dirucotide MBP# 61 azilsartan medoxomil 61 Acthar Gel 61 Pharmacokinetic 61 noninfectious uveitis 61 MIRAPEX 61 Cymbalta duloxetine HCl 61 pimozide 61 pramlintide metreleptin combination 61 Vernakalant 61 postmarketing surveillance 61 amisulpride 61 Acute Decompensated Heart Failure 61 THALOMID 61 esophageal reflux 61 hypercholesterolemic patients 61 Known hypersensitivity 61 BANZEL 61 hepatic enzyme 61 Bosentan 61 iloprost 61 FASLODEX 61 AGGRASTAT R 61 varespladib 61 Vimpat ® 61 hereditary deficiency 61 CINTREDEKIN BESUDOTOX 61 POSIDUR TM 61 acromegalic patients 61 EOquin TM 61 ADVANCE PD 61 Alvesco R 61 liver transplant recipients 61 PHPT 61 gemcitabine Gemzar ® 61 cardiac troponin 61 PhG alpha 1 61 fluticasone salmeterol 61 Squalamine 61 HBeAg 61 NP2 Enkephalin 61 immunosuppressives 61 Torisel 61 PrandiMet TM 61 somatostatin analogues 61 IL 1ß 61 alpha blocker 61 Primary endpoints 61 subgroup analyzes 61 UPLYSO 61 oxaliplatin Eloxatin 61 LPV r