Related by context. Frequent words. (Click for all words.) 74 pharmacodynamic 73 pharmacodynamic effects 70 Pharmacokinetic 69 pharmacokinetic 69 pharmacodynamics 68 imetelstat 67 PXD# 67 Azedra 67 Phase 1b 67 pharmacokinetic profile 67 pharmacokinetic profiles 67 rHuPH# 67 Phase 2a trial 67 Phase 1a 67 xenograft models 67 antitumor activity 66 pharmacokinetic studies 66 pharmacokinetics 66 Secondary endpoints include 66 orally bioavailable 66 vitro experiments 66 tanespimycin 65 CR# vcMMAE 65 radiolabeled 65 Phase Ib 65 nab paclitaxel 65 eniluracil 65 HGS ETR1 65 phase 2a 65 #ME# 65 serum concentrations 64 tolerated dose MTD 64 mRNA expression 64 pharmacokinetic properties 64 GRN#L 64 OXi# 64 dose limiting toxicities 64 Phase Ia 64 placebo controlled clinical 64 pertuzumab 64 Secondary endpoints 64 C1 INH 64 phase IIa 64 tolerability 64 Secondary endpoints included 64 safety tolerability pharmacokinetics 64 Phase 1b trial 64 tumor lysis syndrome 64 NGX# 64 CA4P 64 safety tolerability 63 limiting toxicity 63 administered subcutaneously 63 immunogenicity 63 Lenalidomide 63 serologic 63 TG# [001] 63 MAXY G# 63 PK PD 63 noninferiority 63 HER2 positive metastatic breast 63 Cloretazine R VNP#M 63 pharmacologic 63 IMC A# 63 genotypic 63 Tolerability 63 genotoxicity 63 DAVANAT 63 multiple ascending dose 63 neutralizing antibody 63 mg kg dose 63 secondary efficacy endpoints 63 immunohistochemical 63 Phase 1b clinical 63 Phase 2a clinical 63 NEUMUNE 63 CYT# 63 immunologic 62 dose escalation 62 cytotoxicity 62 MAP# 62 CoFactor 62 neoadjuvant chemotherapy 62 IMGN# 62 SCH # 62 achieved statistical significance 62 axitinib 62 antithrombotic 62 decitabine 62 Phase IIa clinical 62 antitumor 62 peripheral blood mononuclear 62 Phase 2b study 62 neoadjuvant 62 Pivotal Phase III 62 clinically relevant 62 confirmatory Phase III 62 dose cohorts 62 dose escalation study 62 histopathological 62 RG# [001]