Related by context. Frequent words. (Click for all words.) 81 pharmacokinetics 73 tolerability 72 immunogenicity 72 pharmacokinetic profile 71 pharmacodynamic 66 tolerability profile 66 safety tolerability 66 Phase IIa 65 Phase Ib 65 dose escalation study 64 Phase IIa clinical 64 clinical trial 64 efficacy 64 preclinical studies 63 Phase 1b 63 Phase III clinical 63 dose escalation 63 preclinical 62 double blind placebo 62 antiviral activity 62 RDEA# 61 dosing regimens 61 placebo controlled 61 Phase IIb 61 CYT# 61 Phase 2a 60 Phase 2b clinical 60 dosing 59 vivo 59 bioequivalence 59 Phase III trials 59 pivotal Phase III 59 antitumor activity 59 randomized placebo controlled 59 clinical trials 59 Phase III 58 mg dose 58 Phase IIb clinical 58 pivotal Phase 58 randomized double 57 bioavailability 57 PMX # 57 Phase 2b 57 Phase III clinical trials 57 CK # 57 Phase IIb trial 57 RG# [001] 56 ADX# 56 perifosine 56 dosing regimen 56 pharmacologic 56 clinically meaningful 55 investigational 55 clinically relevant 55 randomized clinical 55 monotherapy 55 pharmacological 55 Preclinical 54 plasma concentrations 54 INCB# [002] 54 randomized Phase 54 preclinical models 54 AEZS 54 randomized controlled 54 oral formulation 54 clinical 54 primary endpoint 53 Phase II 53 multicenter 53 orally administered 53 randomized 53 blind randomized placebo 53 randomized clinical trials 53 sunitinib 53 ANA# 53 evaluable patients 53 docetaxel 53 naproxcinod 53 secondary endpoints 53 APD# 53 Zenvia 53 ALKS 53 administered orally 53 picoplatin 53 investigational drug 53 5 FU 53 demonstrated statistically significant 52 AZD# 52 non inferiority 52 TMC# [001] 52 blind randomized 52 vitro 52 XL# [003] 52 blind placebo controlled 52 primary endpoints 52 immunological 52 Dosing 52 Vidaza 52 sitagliptin 52 MGCD# [002] 52 evaluable