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(Click for frequent words.) 71 phosphate S1P 70 transcriptional activation 70 intracellular signaling pathways 70 AT1R 70 non coding RNA 69 C5aR 69 cathepsins 69 sphingolipid 69 apoptotic pathway 69 neuromuscular junction 69 Hedgehog signaling 68 secretory pathway 68 trans splicing 68 potent inhibitors 68 intercellular signaling 68 MAP kinases 68 lysosomal 68 apoptosis pathways 68 RANK Ligand 68 potently inhibit 68 chemokine receptor 67 membrane receptors 67 Wnt signaling pathway 67 selective inhibition 67 Oncogenic 67 neurite outgrowth 67 granzyme B 67 cytolytic 67 intracellular proteins 67 serine proteases 67 Cathepsin B 67 Flt3 67 serine protease 67 serine threonine kinase 67 eotaxin 67 anticancer therapeutics 67 intracellularly 67 selectively inhibit 67 humanized monoclonal antibodies 67 histone deacetylase HDAC 67 E#F# 67 protein tyrosine kinase 67 P#X# receptor 67 CB2 receptor 67 peroxisome 67 Src kinase 67 cAMP signaling 67 EphA2 67 proteoglycan 67 cyclic AMP cAMP 67 retinoic acid receptor 67 inverse agonist 67 proto oncogene 67 mesenchymal cell 67 LSD1 67 immunoregulatory 67 cytoprotective 67 lysophosphatidic acid LPA 67 XL# inhibits 67 mitogen activated protein kinase 67 A3 adenosine receptor 67 telomerase inhibitor 67 pathophysiological effects 66 signaling cascades 66 renal fibrosis 66 VE cadherin 66 E3 ubiquitin ligase 66 transcriptional regulation 66 beta amyloid peptide 66 γ secretase 66 TXNIP 66 adhesion molecule 66 5 HT2A serotonin 66 protein CETP 66 ERK1 2 66 hypoxia inducible factor 66 Epstein Barr Virus EBV 66 Arp2 3 66 kidney urologic 66 oncoprotein 66 prostaglandin synthesis 66 Protein Kinase C 66 enzymatic pathways 66 sphingolipids 66 selectively inhibited 66 glutamate receptors 66 JAK2 enzyme 66 peptide hormone 66 FGFs 66 Rho GTPases 66 Gamma secretase 66 MAP kinase 66 aberrantly activated 66 Macrophage 66 small molecule agonists 66 druggable target 66 G Protein Coupled 66 vascular endothelial cells 66 potent inhibition 66 antisense oligonucleotides 66 p#/CBP 66 primary cilia 66 poly ADP ribose polymerase 66 Cytotoxic T 66 splice variants 66 messenger molecule 66 intracellular 66 hedgehog pathway 66 nicotinic acetylcholine receptor 66 PI3 kinase 66 acetylcholine receptor 66 potently inhibited 66 CCR2 66 kinase pathway 66 IL 1β 65 androgen receptor AR 65 pleiotropic 65 TTR gene 65 FGFR3 65 TNFR 65 4E BP1 65 synaptogenesis 65 potent inducer 65 neuroinflammatory 65 chemokine 65 Upregulation 65 endogenous ligands 65 VEGF receptor 65 Hedgehog signaling pathway 65 osteogenic differentiation 65 EGF receptor 65 synovial cells 65 siRNA therapeutic 65 MMP9 65 Fibroblast Growth Factor Receptor 65 neurotransmitter receptors 65 regulates gene expression 65 receptor mediated endocytosis 65 apoE 65 Integrins 65 autophagic 65 serine threonine 65 TGF alpha 65 intracellular signaling 65 adipogenic 65 CCR1 65 MDR1 65 Fc receptor 65 MAPK pathway 65 LRP5 65 deacetylation 65 nucleolin 65 engineered RAP peptides 65 NKX#.# 65 NF κB 65 proteosome 65 leukocyte adhesion 65 upregulates 65 tRNA synthetase 65 kinase PI3K 65 #HT#A 65 ubiquitin ligase 65 FGFR1 65 adipokines 65 metalloenzymes 65 microRNAs miRNAs 65 cellular pathways 65 ENMD # 65 secreted protein 65 β catenin 65 c MET 65 lymphoid cells 65 tumorigenicity 65 ERK pathway 65 Hedgehog pathway 65 costimulatory 65 Clusterin 65 cyclin dependent kinases 65 c myc 65 small molecule modulators 65 neurotransmitter glutamate 65 receptor tyrosine kinases RTKs 65 inflammatory cytokine 65 cytokine signaling 65 Rap1 65 induces apoptosis 65 histone deacetylase 65 mTOR mammalian target 65 RNAi therapeutic targeting 65 tissue fibrosis 65 focal adhesion kinase FAK 65 virulence determinants 65 matrix metalloproteinases 65 uPAR 65 cytotoxins 65 ERK signaling 65 Anticalins ® 64 TGF ß 64 redox active 64 phosphatidylinositol 3 64 lymphotoxin 64 autocrine 64 synaptic transmission 64 endosomal 64 molecular signaling pathway 64 pharmacological inhibition 64 adenoviral 64 CD# ligand 64 potent cytotoxic 64 monocytes macrophages 64 PKC isoforms 64 biologic pathway 64 TH# cells 64 HDAC6 64 cyclooxygenase 2 64 NKG2D 64 glucocorticoid receptors 64 eicosanoid 64 MTP inhibitor 64 HCV replication 64 subtype selective 64 SIRT2 64 FGFR 64 cyclin dependent kinases CDKs 64 pro angiogenic 64 mRNA translation 64 tyrosine kinase receptor 64 acetylcholinesterase AChE 64 PECAM 64 FKBP# 64 uPA 64 protein kinases 64 phosphorylates 64 chimeric monoclonal antibody 64 ubiquitin ligases 64 M1 muscarinic 64 novel peptide 64 S1P 64 telomerase RNA 64 Fas ligand 64 NF kB signaling 64 nAChRs 64 tyrosine kinase 64 synthetases 64 posttranslational modifications 64 receptor mediated 64 5 lipoxygenase 64 osteoprotegerin 64 receptor PPAR 64 IRAK1 64 immunotoxin 64 downregulate 64 actin cytoskeleton 64 tumor stroma 64 Skp2 64 vimentin 64 TGF beta1 64 GSK3B 64 c myc gene 64 AtuPLEX 64 histone acetylation 64 stem cell pluripotency 64 acinar 64 leukocyte recruitment 64 ornithine decarboxylase 64 lymphangiogenesis 64 somatostatin 64 cell signaling pathways 64 #T# L1 64 Nedd4 64 intracellular accumulation 64 vacuolar 64 neuronal nicotinic receptors NNRs 64 intracellular bacteria 64 basolateral 64 homodimers 64 antiproliferative activity 64 pRb 64 somatostatin receptors 64 neuronal nitric oxide synthase 64 cathepsin K 64 EGFR pathway 64 sRNA 64 Treg cell 64 selective antagonists 64 BCL#A 64 osteoclast 64 transmembrane proteins 64 pDCs 64 USP# 64 DNA methyltransferases 64 chemokine receptors 64 keratinocyte 64 paxillin 64 microRNA miRNA 64 constitutively expressed 64 deacetylase inhibitors 64 receptor molecule 64 mda 7 64 PcG 64 factor receptor FGFR 64 molecular biomarkers 64 TNF receptors 64 cyclin dependent kinase 64 RNA silencing 64 histone deacetylases 64 mediated inhibition 64 P#X# 64 induced neuronal 64 protein tyrosine phosphatases 64 oligomerization 64 CENP E 64 Receptors GPCRs 64 Dystrophin 64 RAS RAF MEK 64 inhibiting tumor 64 antibody mediated 64 post transcriptional 64 V#F mutation 63 RNAi pathway 63 caveolin 1 63 PDGF receptor 63 outer membrane proteins 63 transduce 63 alpha subunit 63 microtubule dynamics 63 proteinase 63 Rab# 63 T#M 63 cypin 63 mTOR signaling pathway 63 HIF 1α 63 FGF receptor 63 Htt 63 TRAIL induced apoptosis 63 biased ligand 63 Pim kinases 63 regulating gene expression 63 metabolic enzymes 63 NFAT 63 neurturin 63 cAMP dependent 63 Skeletal muscle 63 p# MAPK 63 PPARg 63 cell adhesion molecule 63 tumor suppressor protein 63 receptor tyrosine kinase 63 telomerase reverse transcriptase 63 prostaglandin E2 63 Aurora kinase 63 ERK1 63 LRP1 63 NKT cell 63 NS4B 63 potent stimulator 63 E3 ligase 63 antagomirs 63 osteoblast 63 fast skeletal troponin 63 potent antiproliferative 63 biosynthetic pathways 63 Anticalins R 63 PKD1 63 antimitotic 63 genes encode proteins 63 pre mRNA splicing 63 anti apoptotic 63 peroxisomes 63 BRAF protein 63 reversibly inhibits 63 mitotic kinesin 63 dopamine transporter DAT 63 immuno modulatory 63 cofactors 63 sortilin 63 IL #p# 63 cellular signaling pathways 63 MAP kinase pathway 63 fatty acid amide hydrolase 63 encodes protein 63 mTOR signaling 63 Id1 63 KLF4 63 AMPA receptor 63 LIS1 63 Kv#.# 63 BMP4 63 effector function 63 proliferative disorders 63 IAP inhibitor 63 endocytic 63 MEK ERK 63 cyclic peptide 63 synapse formation 63 COX2 63 MT1 MMP 63 Locked Nucleic Acid LNA 63 Hypoxia Inducible Factor 63 mitogen activated protein kinases 63 peroxisome proliferator activated 63 phosphatases 63 alpha MSH 63 signal transduction 63 druggable targets 63 Nod1 63 bioactive molecules 63 bacterial enzyme 63 tumor antigens 63 TGF b 63 protein kinase C 63 HER1 63 metalloprotease 63 nitric oxide synthase 63 fibrogenesis 63 oncogenesis 63 ribonuclease 63 plasminogen 63 p# pathway 63 short hairpin RNAs 63 mRNA molecules 63 specific lectin receptors 63 intercellular communication 63 CDK5 63 ß catenin 63 receptor gamma 63 podocyte 63 enzyme AMPK 63 NFkappaB 63 oncomodulin 63 MDSCs 63 antisense molecules 63 CCR3 63 hydrolases 63 transmembrane receptor 63 JAK2 63 DNMT1 63 PTPN# 63 dimeric 63 glycolipids 63 peptide antigens 63 gene rearrangements 63 anionic backbone 63 Rab5 63 JAK#/JAK# 63 ryanodine receptor 63 HIV reverse transcriptase 63 RUNX3 63 costimulation 63 Tß4 63 induce apoptosis 63 TLE3 63 Factor VEGF 63 antimetastatic 63 immune modulator 63 enzyme inhibitor 63 ADAMTS# 63 apoptosis induced 63 BCL2 63 MMP2 63 synaptic vesicle 63 fibrotic disease 63 neuronal dysfunction 63 nanoparticle aggregates 63 beta1 integrin 63 Immunohistochemical analysis 63 COX enzymes 63 Neuropeptide Y 63 BChE 63 CXCL# 63 beta adrenergic receptors 63 IGF 1R 63 NNRs 63 NS5B 63 oncogenic signaling 63 proapoptotic 63 proteolysis 63 TrkB 62 neurotrophic 62 SIRT1 gene 62 Factor Receptor 62 GABAA receptors 62 JAK kinases 62 overactivation 62 Smac mimetics 62 fibrillin 1 62 HIF 1alpha 62 granulosa cell 62 nucleic acid molecules 62 transactivation 62 Epidermal Growth Factor 62 Histone deacetylase 62 ARF1 62 cyclic nucleotide 62 efflux pump 62 CCR9 62 ESBA# 62 intracellular signal transduction 62 cyclin dependent kinase inhibitor 62 TLR8 62 PAR1 62 protein conformation 62 inhibit angiogenesis 62 upregulating 62 NR#A# 62 phosphoinositide 62 KRAS oncogene 62 selectively inhibits 62 biochemical pathway 62 NeuroTrans TM 62 p# subunit 62 coreceptor 62 subcellular compartments 62 microglial 62 Fibroblast 62 FOXO3a 62 subventricular zone 62 SCD1 62 acyl CoA 62 eIF4E 62 H#K#me# 62 virulence genes 62 galectins 62 osteogenic 62 PI3K AKT 62 MAPKs 62 mediated apoptosis 62 c myb 62 excitotoxic 62 selective inhibitors 62 hypermethylated 62 ribonucleoprotein 62 Hh pathway 62 alveolar macrophages 62 CTGF 62 thymidylate synthase TS 62 protein actin 62 sphingosine 1 62 tRNA synthetases 62 Src kinases 62 tumor antigen 62 catenin 62 heterochromatic 62 polyketides 62 GABA receptor 62 downregulation 62 lymphoid organs 62 tumor suppressor PTEN 62 LPA1 62 peroxisomal 62 RNA synthesis 62 interleukin 1beta 62 phosphoprotein 62 biogenesis 62 PI3K Akt 62 IGF IR 62 epigenetic modification 62 p# activation 62 HOTAIR 62 small molecule activators 62 GPC5 62 glycosylated 62 ErbB3 62 thrombin receptor 62 SGK1 62 basal lamina 62 FGFR2 62 anaphase promoting complex 62 ubiquitylation 62 intracellular pathways 62 TMEM#B 62 Curaxins 62 genotoxic stress 62 inducible nitric oxide synthase 62 Dysregulation 62 antisense inhibitors 62 CD#b 62 peroxidase 62 cytoplasmic domain 62 B lymphocyte stimulator 62 tropomyosin 62 IFN g 62 retinoid X 62 oncogenic transformation 62 extracellular signal 62 hyperactivation 62 PI3K pathway 62 cardiac fibroblasts 62 eIF 4E 62 GNAQ 62 glioma cells 62 vesicle formation 62 VEGFR2 62 antiapoptotic 62 CCL# 62 Th2 cytokines 62 carbohydrate antigens 62 membrane protein 62 neuroinflammation 62 lysosomal enzyme 62 lipid rafts 62 P glycoprotein 62 aldose reductase 62 protein synthesis machinery 62 ligase 62 Ii protein 62 tyrosine phosphorylation 62 lymphatic vasculature 62 IKKß 62 aberrant activation 62 CXCR4 receptor 62 mTORC1 62 Peripheral nerves 62 effector memory 62 LRP6 62 cell motility 62 osteoclast formation 62 copper zinc superoxide 62 rRNA 62 KIAA# 62 ligand binding 62 thymidylate synthase 62 noncoding RNAs 62 polyamine 62 thymosin beta 4 62 p# mitogen activated 62 mechanotransduction 62 eNOS 62 receptor subtypes 62 diagnostic biomarkers 62 receptor alpha 62 Tissue Factor 62 miR #b [002] 62 spectrin 62 alpha#beta# integrin 62 IFN γ 62 cardiac myocytes 62 alpha TNFa 62 targeting CD# 62 NFκB 62 siRNA therapeutics 62 macrophage activation 62 Vpr 62 mitochondrial electron 62 IL 1ß 62 antitumor 62 Cyclin D1 62 Abeta# 62 protein alpha synuclein 62 N Myc 62 protein biosynthesis 62 hematopoietic progenitors 62 protein misfolding 62 guanosine 62 cytostatic 62 adenosine A2A receptor 62 receptor CXCR4 62 M2 subunit 62 antitumoral 62 Overexpression 62 axon guidance 62 TNF α 62 anti amnesic 62 ENaC 62 Pten 62 histone deacetylases HDAC 62 UCP2 62 Huntingtin 62 tumor suppressors 62 NMDA N 62 isotypes 62 myopathies 62 collagens 62 excess TNF alpha 62 Histone 62 PI3K/mTOR 62 effector molecules 62 Alfacell proprietary ribonuclease 62 estrogen receptor beta 62 apoptosis inducing 62 viral proteins 62 mesenchymal stromal cells 62 Runx2 62 serotonin receptor 62 histone deacetylation 62 TGF β 62 RIP1 62 cyclins 62 enkephalin 62 ligases 62 downregulates 62 dopamine transporter 62 integrin receptors 62 Kinases 62 nucleases 62 pathological hallmark 62 isomerase 62 coexpression 62 PKM2 62 Wnts 62 NF kB pathway 62 coactivator 62 lysyl oxidase 62 ectopic expression 62 iNOS 62 mediating pathological inflammation 62 SETDB1 62 phosphorylate 62 tumor suppressor proteins 62 IL 1beta 62 neurofibromin 62 defective CFTR protein 62 BMP signaling 62 TLR9 62 amyloid ß 62 bone morphogenetic proteins 62 CagA 62 miR# 62 osteoclast activity 62 Leydig cells 62 messenger ribonucleic acid 62 lipid synthesis 62 monocyte macrophage 62 tumor microenvironment 62 cellular organelles 62 PARP inhibition 62 microvascular endothelial cells 62 neurotrophins 62 hormone gastrin 62 methyltransferases 62 MetAP2 62 inhibitory receptor 62 Akt3 62 phagocytosis 62 vascular endothelial 62 LDL receptor 62 podocytes 62 cholesterol homeostasis 62 RANK ligand 62 ribonucleotide reductase 62 Smad3 62 5 HT4 receptor 62 insertional mutagenesis 62 H#K# [002] 62 drug metabolizing enzymes 62 osteoblastic 62 HER2 neu 61 prostanoid 61 cMET 61 GRNOPC1 contains 61 LPA1 receptor 61 diagnostic biomarker 61 deacetylase 61 PAK1 61 peptidic 61 microRNA molecules 61 protein encoded 61 functional polymorphism 61 extracellular matrix ECM 61 synthetase 61 triterpenoids 61 transcriptional repressor 61 Drosha 61 adipocytes fat 61 MAPK 61 WASp 61 FSH receptor 61 downregulating 61 neurotrophic factors 61 posttranslational modification 61 Galectins 61 Fc fusion protein 61 neoplastic transformation 61 FasL 61 Protein folding 61 transient receptor 61 perivascular 61 therapeutically relevant 61 short interfering RNA 61 synthetic siRNA 61 ribonucleic acids 61 neuronal synapses 61 chromatin structure 61 CXCL5 61 ubiquitination 61 muscarinic receptors 61 glycosyltransferase 61 osteopontin OPN 61 humoral immunity 61 PluriCells TM 61 human airway epithelial 61 TRPV4 61 BubR1 61 thromboxane A2 61 mRNA sequences 61 coagulation cascade 61 missense mutations 61 transmembrane protein 61 proteases 61 HDAC enzymes 61 noradrenergic 61 lipid homeostasis 61 epigenetic regulation 61 cytokine receptor 61 caspase activation 61 retinoblastoma Rb 61 #beta HSD1 61 synthetic peptides 61 ligand induced 61 gliosis 61 endothelial activation 61 epithelial barrier 61 inhibit viral replication 61 clonogenic 61 hematopoietic cells 61 Myeloperoxidase 61 Cdc7 61 cytotoxic T lymphocyte 61 matrix metalloproteases 61 soluble receptor 61 Eg5 61 transferrin receptor 61 c MYC 61 oral JAK1 61 TGF ß1 61 factor GDNF 61 nAChR 61 anti CD3 61 NF kappaB activation 61 NS5A 61 cytochrome P# inhibition 61 intracellular pathogens 61 matrix metalloproteinases MMPs 61 nucleolar 61 small interfering RNA 61 steroidogenic 61 NR2B subunit 61 previously uncharacterized 61 EP1 receptor 61 O. volvulus 61 calcineurin 61 miR #a [002] 61 myeloproliferative diseases 61 mutated protein 61 oncoproteins 61 Smoothened 61 noncoding RNA 61 CB1 receptor 61 basophils 61 proline residues 61 neuroprotective properties 61 Th# cells 61 immune effector 61 nitric oxide synthase NOS 61 effector functions 61 histone deacetylase inhibitors 61 gut mucosa 61 enzyme beta secretase 61 adipogenesis 61 Phosphorylation 61 selectively inhibiting 61 dependent RNA polymerase 61 oligomeric 61 EGFR HER2 61 fibrocytes 61 chaperone protein 61 flavopiridol 61 ribosomal RNA rRNA 61 methyl D aspartate 61 Janus Kinase 61 allosteric 61 dysregulated 61 RNA polymerases 61 FGF signaling 61 GCN2 61 galectin 61 rapamycin mTOR 61 neuronal differentiation 61 Epothilones 61 fatty acid synthase 61 PPARγ 61 dopamine D1 61 mRNA cleavage 61 ribonucleic acid RNA 61 GPR# [002] 61 peptibody 61 malignant prostate 61 SWI SNF 61 prolyl 61 endosomal release 61 heparanase 61 tumor angiogenesis 61 RANTES 61 antiproliferative effects 61 selective kinase inhibitor 61 mutant enzymes 61 DNA demethylation 61 apical membrane 61 Mucosal 61 dimerization 61 IGF1R 61 JAK3 61 micro RNAs 61 monogenic 61 eukaryotic cell 61 trimeric 61 enzyme COX 61 HCV protease 61 antigen receptor 61 receptors PPARs 61 sd rxRNA compounds 61 RANKL 61 superoxide dismutase 61 polycystin 61 vitro assay 61 adenosine receptor 61 RNA antagonist 61 tumorigenesis 61 immune modulatory 61 plasma kallikrein 61 intestinal epithelial cells 61 hyperphosphorylation 61 cyclooxygenase COX 61 P#X# receptors 61 hepatic stellate cells 61 UsiRNAs 61 toxic amyloid beta 61 ErbB1 61 oxidative phosphorylation 61 Abeta peptide 61 CEACAM1 61 IRS1 61 VIPR2 61 oncolytic 61 antisense RNA 61 Notch receptor 61 hypothalamic pituitary adrenal axis 61 β1 61 selective modulator 61 cytokine receptors 61 glial derived neurotrophic 61 PHD2 61 amyloid peptide 61 circadian clock genes 61 p# Shc 61 microvesicles 61 ERK2 61 oncogenic 61 VEGF protein 61 bone marrow mesenchymal stem 61 S#P# 61 hypocretin neurons 61 histone H4 61 tumor metastasis 61 GAD# 61 histone acetyltransferase 61 excitatory neurotransmitter 61 cyclin E 61 ncRNA 61 protein homeostasis 61 transcriptionally active 61 PROT biotechnology 61 RNA ribonucleic acid 61 siRNA knockdown 61 genus Plasmodium 61 calpain 61 tenascin C 61 aT cell 61 GLUT4 61 intestinal mucosa 61 cyclic guanosine monophosphate cGMP 61 filamentous fungus 61 RNA splicing 61 Microtubule 61 FUS1 61 cofactor 61 sCD# 61 neurosteroid 61 immune modulating 61 protein tyrosine 61 FAAH 61 ErbB3 HER3 61 chromatin remodeling 61 Pichia pastoris 61 targeting PCSK9 61 APOBEC3G 61 organogenesis 61 Wnt pathway 61 chromosome condensation 61 attach auristatin 61 elastase 61 huntingtin 61 posttranslational 61 nicotinic receptors 61 LMNA 61 histone modifications 61 5 HT2A receptor 61 antimicrobial peptide 61 transfer RNA tRNA