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(Click for frequent words.) 72 TGF beta1 72 mediated inhibition 71 proteoglycan 71 M1 muscarinic 71 epididymal 70 phosphoprotein 70 autophagic 70 Amino acid 70 vesicle fusion 70 γ secretase 70 antiapoptotic 70 osteoblastic 69 eIF2 69 ERK1 2 69 F actin 69 Oncogenic 69 immunoreactive 69 TGF ß 69 FGFR3 69 osteogenic 69 Western blotting 69 haematopoietic 69 hypothalamic pituitary 69 neurite outgrowth 69 GLUT4 69 immunostaining 69 P cadherin 68 Rab5 68 oligomerization 68 DNA demethylation 68 ERK phosphorylation 68 dimeric 68 vimentin 68 intercellular signaling 68 mitotic progression 68 MT1 MMP 68 upregulates 68 metaplasia 68 ABL1 68 nitrotyrosine 68 VE cadherin 68 pyrimidine 68 subcellular localization 68 acinar 68 degranulation 68 SOCS3 68 Endothelial 68 occludin 67 ERK signaling 67 transgene expression 67 Annexin V 67 fibrin deposition 67 endothelial activation 67 ligand binding 67 synovial 67 Fibroblast 67 transgenic mice expressing 67 tumor necrosis 67 protein tyrosine phosphatase 67 tropomyosin 67 vascularisation 67 HIF 1a 67 IL 1ß 67 adipogenic 67 chondrocyte 67 methyltransferase 67 Alkaline Phosphatase 67 p#NTR 67 Microtubule 67 renal fibrosis 67 Clinical Relevance 67 NKG2D 67 glycosylated 67 eicosanoid 67 mononuclear 67 osteoclast 67 lymphangiogenesis 67 CD# expression [001] 67 complexation 67 tumorigenicity 67 immunoregulatory 67 RT qPCR 67 FGFR4 67 microglial 67 ß catenin 67 proximal tubule 67 secretory pathway 67 Fc receptor 67 gastric carcinoma 67 Upregulation 67 peroxisomal 67 paxillin 67 steroidogenic 66 myofibroblast 66 microvessel density 66 trophoblast cells 66 junctional 66 posttranslational modifications 66 RRM1 66 proteolytic cleavage 66 FGF signaling 66 pro angiogenic 66 RAS RAF MEK 66 p# activation 66 TGF ß1 66 Dysregulation 66 collagen degradation 66 xenobiotic 66 thymidylate synthase TS 66 monocytes macrophages 66 ß amyloid 66 ADAMTS# 66 peroxidation 66 interferon γ 66 ERK activation 66 RNase L 66 Lymph node 66 1beta 66 mitogenic 66 Mutational 66 modulatory 66 cytokeratin 66 cardiac myocytes 66 extraocular 66 hexose 66 metabolomic profiles 66 erythropoiesis 66 chemosensitivity 66 transgenic mouse models 66 Immunohistochemical 66 cell adhesion molecule 66 humoral immunity 66 basic fibroblast 66 E#F# 66 downregulates 66 striatal dopamine 66 polyamine 66 astrocytic 66 IFN g 66 pDC 66 T#M 66 vWF 66 acetylcholine receptor 66 glomerular 66 TNF α 66 eNOS 66 immunofluorescence microscopy 66 ERBB2 66 ribosomal protein 66 tenascin C 66 CD1d 66 keratinocyte 66 osteolytic 66 metabolizing enzyme 66 leukocyte adhesion 66 differential gene expression 66 atherogenesis 66 Smad4 66 isoenzyme 66 autoregulation 66 Histone 66 posttranslational modification 66 pertussis toxin 66 H#K#me# 66 Cathepsin B 66 Macrophage 66 Clusterin 66 p# MAPK 66 constitutively expressed 66 choroidal 66 ERalpha 66 glutamatergic 66 radiosensitivity 66 intraventricular 65 Skeletal muscle 65 Vps# 65 granzyme B 65 SSc 65 Schematic representation 65 hematopoietic progenitor cells 65 cathepsin B 65 adipocyte 65 VEGF expression 65 inducible nitric oxide synthase 65 glycosyltransferase 65 secretase 65 intracellular signal transduction 65 costimulatory 65 IL #p# 65 NF kappaB activation 65 osteoconductive 65 tumoral 65 PLA2 65 TIMP 1 65 coexpression 65 ultrastructure 65 CEACAM1 65 S nitrosylation 65 transcriptional repressor 65 P selectin 65 redox active 65 leiomyoma 65 osteoblast 65 bronchoalveolar lavage 65 FGFR1 65 inflammatory cytokine 65 replicase 65 intermediate filaments 65 immunohistochemical 65 MMP# 65 myofibroblasts 65 interleukin IL -# 65 TRPV4 65 pleiotropic effects 65 platelet adhesion 65 miRNA expression 65 antiproliferative activity 65 Glycosylation 65 cAMP signaling 65 hypothalamus pituitary 65 GPx 65 immunomodulation 65 nucleolar 65 IgG4 65 transabdominal 65 polycystin 65 Aâ 65 proteolysis 65 endocytic 65 nitric oxide synthase 65 cisplatin resistant 65 nonvascular 65 Nedd4 65 RQ PCR 65 oligomer 65 clonogenic 65 metalloproteinase 65 immunohistochemical analysis 65 aggrecan 65 Ferritin 65 cytoplasmic domain 65 matrix metalloproteinases 65 immunoreactivity 65 serine protease 65 malignant prostate 65 Cytotoxic 65 IFN γ 65 ARF1 65 protein biosynthesis 65 immunoblotting 65 covalently bound 65 IL6 65 thyroid carcinoma 65 mTOR signaling pathway 65 CD#c 65 proapoptotic 65 MDR1 65 beta actin 65 Transferrin 65 tubule 65 siRNA knockdown 65 prostaglandin synthesis 65 antibody mediated 65 Confocal microscopy 65 ß1 65 mRNA expression 65 MMP9 65 intratumoral 65 transmural 65 cyclic adenosine monophosphate cAMP 65 basolateral 65 annexin V 65 capillary endothelial cells 65 vascular endothelial cells 65 CCL# 65 effector function 65 β1 65 oncogenic transformation 65 ectopic expression 65 amyloid formation 65 oocyte maturation 65 neuronal differentiation 65 Fig. 2b 65 TGF β 65 TET2 65 synthase TS 65 intimal hyperplasia 65 Fas ligand 65 sGC 65 macrophage infiltration 65 protein conformation 65 Apoptotic 65 monomeric 65 bilayers 65 PHD2 65 Hematopoietic 65 Dopaminergic 65 PEDF 65 ERK pathway 65 microsomal 65 protease activated 65 endonuclease 65 polynucleotides 65 Cyclin E 65 alveolar epithelial cells 65 Integrins 65 IRE1 65 potent cytotoxic 65 neurotrophic 65 tyrosine phosphorylation 64 myocyte 64 matrix metalloproteinases MMPs 64 NFkappaB 64 Phosphorylation 64 factor HGF 64 seminal vesicle 64 proteolytic 64 Intravascular 64 Inhibitory 64 phospholipase 64 Smad3 64 Protein Kinase C 64 bronchial epithelial cells 64 NKT cell 64 clonal expansion 64 proteolytic activity 64 MTT assay 64 TNFalpha 64 carcinoembryonic antigen 64 gelsolin 64 bacterial virulence 64 fibrotic disease 64 PTPN# 64 neointimal hyperplasia 64 neovascularization 64 ligand receptor 64 neurogenic inflammation 64 overactivation 64 FGFs 64 LPS induced 64 mucinous 64 deacetylation 64 Figure 1C 64 P2X 64 ribonucleoprotein 64 adducts 64 natriuretic 64 lysosomal enzyme 64 Figure 1A 64 transferrin receptor 64 Immunohistochemical staining 64 reticular 64 lesional 64 GPI anchored 64 TGFβ 64 protein tyrosine kinase 64 DNMT1 64 Histologic 64 CYP #D# 64 NMDAR 64 c Src 64 immune modulatory 64 MAPK pathway 64 gastric carcinomas 64 depolarizing 64 neuronal dysfunction 64 Superoxide 64 HepG2 cells 64 endosomal 64 microvessel 64 cytidine 64 natriuretic peptides 64 PDGFR 64 ischemic mitral regurgitation 64 Flt3 64 prostatic tissue 64 FKBP# 64 cytokine signaling 64 cell adhesion molecules 64 Purkinje cell 64 Fibroblast Growth Factor Receptor 64 nucleases 64 amyloid β 64 T2 weighted images 64 tryptase 64 cytochrome c oxidase 64 nitric oxide synthase NOS 64 metastatic lymph nodes 64 CCR9 64 anti CD3 64 BMP signaling 64 hypothalamic pituitary adrenal axis 64 osteoblast differentiation 64 #S subunit 64 branching morphogenesis 64 pulsatility 64 myopathies 64 uPA 64 heparanase 64 intracellular signaling 64 catenin 64 selective inhibition 64 immunocytochemistry 64 colocalization 64 STAT3 signaling 64 CaM 64 AT1R 64 vasodilatory 64 VEGFR1 64 epithelia 64 adenylate cyclase 64 PTHrP 64 xenograft 64 vacuolar 64 myometrium 64 vasodilatation 64 PKC isoforms 64 FDG-PET/CT 64 PARP1 64 Immunohistochemical analysis 64 HCT# 64 CD# ligand 64 ESCRT 64 fluorescently tagged 64 CagA 64 Lyn kinase 64 chromosome condensation 64 galectin 64 gastrointestinal stromal tumors GISTs 64 cytoprotective 64 immunodominant 64 scintigraphic 64 extracellular matrix ECM 64 Phenotypic 64 SMAD4 64 hERG 64 umbilical vein 64 myeloperoxidase 64 alpha subunit 64 KLF4 64 Wnts 64 endonucleases 64 DNase 64 noradrenergic 64 androgen receptor AR 64 induced phosphorylation 64 focal adhesions 64 GAPDH 64 spectrin 64 thyrotropin 64 prostanoid 64 iRGD 64 thymic 64 cytotoxicity assays 64 FSH receptor 64 COL#A# 64 Notch1 64 thrombus formation 64 vitro assay 64 N glycan 64 HepDirect prodrug 64 flavopiridol 64 interleukin 1beta 64 murine models 64 IL 1β 64 colorectal adenocarcinoma 64 splenocytes 64 proteomic analysis 64 benign neoplasms 64 Anticalins ® 64 tissue oxygenation 63 Secretase 63 gene inactivation 63 LRP5 63 phosphorylates 63 synovial cells 63 STAT1 63 BMAL1 63 osteogenesis 63 colorectal tumor 63 Ca2 + 63 ectodomain 63 Quantitation 63 rostral 63 aggregated Abeta 63 Lp PLA 2 63 heterochromatic 63 adrenoceptor 63 EF Tu 63 guanosine 63 Htt 63 Mitotic 63 trimeric 63 homodimers 63 mRNA encoding 63 caveolin 1 63 ploidy 63 sarcomere 63 pharmacological inhibition 63 insertional 63 immunofluorescence 63 Neurogenesis 63 histopathologic examination 63 uracil 63 synthases 63 lytic 63 Leydig cell 63 Intracellular 63 immunofluorescence staining 63 constitutively active 63 HDAC6 63 motor neuron degeneration 63 isotypes 63 GABAergic interneurons 63 acetylcholinesterase AChE 63 JAK2 enzyme 63 potent inducer 63 Rap1 63 4E BP1 63 transient transfection 63 MEK1 63 pRb 63 aminotransferase 63 neuronal signaling 63 activin 63 ADAM# 63 Fibroblasts 63 PARP inhibition 63 tissue fibrosis 63 mitochondrial enzyme 63 Cytochrome 63 p# subunit 63 osteogenic differentiation 63 esophageal carcinoma 63 hypoperfusion 63 RNA polymerases 63 VSV G 63 Microarray analysis 63 intrahepatic 63 antiangiogenic 63 HIF 1α 63 antitumoral 63 CHD5 63 renal cysts 63 intestinal epithelium 63 Cardiotoxicity 63 Overexpression 63 dephosphorylation 63 serine threonine kinase 63 p#Kip# 63 luminal surface 63 multidrug 63 immunofluorescent 63 proline rich 63 trophoblastic 63 Parathyroid hormone 63 Runx2 63 inhibiting mTOR 63 Nicotinic 63 apolipoproteins 63 epithelial barrier 63 PGC 1α 63 urothelial carcinoma 63 translationally 63 tumor perfusion 63 Treg cell 63 mineralocorticoid 63 TXNIP 63 synovial tissue 63 PPARγ 63 hepatocyte 63 functionalization 63 Histopathologic 63 Prolactin 63 hypointense 63 Cadherin 63 striatal 63 LNCaP cells 63 microRNA profiling 63 hypervascular 63 Extracellular 63 CD# CD# 63 urothelial 63 messenger ribonucleic acid 63 receptor mediated 63 radiolabeling 63 Lipoprotein 63 protein glycosylation 63 focally 63 gene rearrangements 63 pulse amplitude 63 amyloid deposition 63 synaptogenesis 63 pleiotropic 63 inactivating mutations 63 PDGF BB 63 osteoclast formation 63 Dehydrogenase 63 Estrogen Receptor 63 PDGF B 63 PDGF receptor 63 triiodothyronine 63 lung epithelium 63 Ki# 63 TLE3 63 HIF 1alpha 63 Monocyte 63 PPARg 63 potent stimulator 63 Activating mutations 63 Sp1 63 VEGF induced 63 fig. S4 63 HER2 overexpression 63 cathepsins 63 cis regulatory 63 Signaling Pathway 63 CTGF 63 tetramer 63 mineralocorticoid receptor 63 acinar cells 63 apoE 63 Transmembrane 63 prostate carcinoma 63 beta subunit 63 disulfide bond 63 Xenograft 63 site directed mutagenesis 63 PDGFR alpha 63 intramolecular 63 osteoprotegerin 63 mitochondrial biogenesis 63 null mice 63 lysosomal 63 plasminogen activator 63 vitro pharmacology 63 coactivators 63 VEGF receptor 63 SCD1 63 cyclase 63 glucokinase 63 Hemodynamic 63 potent antiproliferative 63 kinase domain 63 NR2B subunit 63 β catenin 63 histone acetylation 63 colorectal carcinogenesis 63 SIRT2 63 neuritic 63 annexin 63 γδ T cells 63 beta globin 63 podocytes 63 isomerase 63 lactate dehydrogenase 63 microstructural 63 ribosomal DNA 63 Genistein 63 multiprotein complex 63 bFGF 63 NSCLC tumors 63 BCL2 63 vasoactive 63 lymphatic vessel 63 mRNA translation 63 dorsal root ganglion 63 adipogenesis 63 TGFß 63 type plasminogen activator 63 transferase 63 FK# 63 #T# L1 63 innervation 63 Akt activation 63 JAK STAT 63 intra tumoral 63 thermosensitive 63 acyclic 63 KRAS oncogene 63 leukotriene B4 63 acyltransferase 63 meiotic recombination 63 PECAM 1 63 myocardial function 63 chlamydial 63 transduced 63 Hcrt 63 mycobacterial 63 Mucosal 63 fig. S1 63 proteolytic degradation 63 beta globin gene 63 TGF b 63 thermostable 63 substrate specificity 63 E cadherin expression 63 mediated apoptosis 63 bone morphogenic protein 63 transmembrane receptor 63 hydroxylation 63 serine threonine 62 osteocalcin protein 62 mesangial 62 nodal metastasis 62 FasL 62 heterologous expression 62 c fos 62 aminopeptidase 62 extracellular proteins 62 fast skeletal troponin 62 lymphatic vasculature 62 N acetyl 62 Androgen receptor 62 retinoid X 62 contractile function 62 antitumor efficacy 62 MAP kinase 62 collagens 62 lysates 62 DNA methyltransferases 62 histopathological 62 endoglin 62 syntaxin 62 dermal collagen 62 antiproliferative 62 cyclic AMP cAMP 62 Transcriptome 62 small molecule activator 62 Dietary restriction 62 protein tyrosine phosphatase 1B 62 EGFR signaling 62 thymidine 62 de novo synthesis 62 JNK1 62 mda 7 62 VEGF protein 62 extrahepatic 62 nephron 62 C3 convertase 62 P gp 62 E Cadherin 62 Transcriptional 62 Placental 62 Aromatase 62 Fig. 1D 62 clathrin 62 #ß 62 vasomotor 62 IL 1beta 62 Calcium phosphate 62 lymphoid cells 62 selectively inhibiting 62 actin cytoskeleton 62 NKX#.# 62 solubilization 62 trophoblasts 62 dipeptide 62 diffusion tensor 62 HEK# cells 62 p# Shc 62 subcellular compartments 62 TIMP 62 amino terminal 62 oncogenic mutations 62 photobleaching 62 myocardial necrosis 62 radiographic findings 62 TGF alpha 62 anterograde 62 cytostatic 62 baroreflex 62 NS5B 62 epithelial mesenchymal transition 62 telomere maintenance 62 sphingomyelin 62 Tie2 62 muscarinic receptor 62 MyoD 62 ERK1 62 homodimer 62 protein ligand 62 c MYC 62 Alternative splicing 62 amyloid peptide 62 plasminogen activator inhibitor 62 ventricular myocardium 62 macromolecular complexes 62 antisense inhibition 62 CDK4 62 regulated kinase ERK 62 postsynaptic 62 peritoneal fluid 62 airway hyperresponsiveness 62 TAp# 62 FGF2 62 chemokine receptor 62 multimodality imaging 62 vivo potency 62 Hypothalamic 62 cytosolic 62 vascular endothelial 62 prefrontal cortical 62 stereochemistry 62 Nod1 62 transmembrane protein 62 Rb#/p# 62 Angiotensin II 62 LDL receptor 62 cTnI 62 tenascin 62 amino acid substitutions 62 demethylation 62 TMEM#B 62 C1q 62 PDZ domain 62 peripheral insulin sensitivity 62 PIP2 62 Fc receptors 62 arteriolar 62 neural tissues 62 TEL AML1 62 liposomes containing 62 metalloproteinases 62 erythrocyte 62 antiproliferative effects 62 intracoronary 62 Neuronal 62 colorectal carcinoma 62 neovascularisation 62 microglial activation 62 hypometabolism 62 uPAR 62 cardiac allograft vasculopathy 62 murine model 62 thymosin beta 4 62 #β estradiol 62 phenotypic expression 62 Phylogenetic analysis 62 transcriptionally 62 GLUT1 62 vascularization 62 activate p# 62 cyclic peptide 62 Fibroblast Growth Factor 62 telomere dysfunction 62 Monoclonal 62 presynaptic 62 lipoxygenase 62 lacrimal gland 62 antiangiogenesis 62 homology modeling 62 glutamyl 62 androgen dependent 62 MMP2 62 potent inhibitors 62 gamete formation 62 beta amyloid peptide 62 antimitotic 62 PON1 62 Troponin T 62 Pim kinases 62 Stromal 62 intestinal permeability 62 radicular 62 echo planar 62 protein CETP 62 deacetylase 62 fibrillar 62 conformational changes 62 Prognostic significance 62 receptor mediated endocytosis 62 hamartomas 62 OGG1 62 perivascular 62 Fig. 1C 62 TrkB 62 Rab# 62 bicyclic 62 Abeta# 62 extracellular signal 62 kinase pathway 62 PIGF 62 Autoantibodies 62 multiplanar 62 neuromuscular junction 62 5 HT2A serotonin 62 axon guidance 62 Endometrial 62 Cardiopulmonary bypass 62 Dystrophin 62 lamellar 62 apo B 62 thyroglobulin 62 dermal papilla 62 proteosome 62 monogenic 62 Epstein Barr Virus EBV 62 TOP2A 62 muscarinic 62 RANTES 62 baroreceptor 62 anterior posterior 62 UsiRNAs 62 hypericin 62 1alpha 62 ultrastructural 62 biogenesis 62 hapten 62 secretory 62 spectrophotometric 62 peroxidase 62 NFkB 62 P. gingivalis 62 pressure natriuresis 62 nuclease 62 quantitative computed tomography 62 hyperintensities 62 adherens junctions 62 efferent 62 gene rearrangement 62 cell lysis 62 neuroinflammation 62 purine 62 motoneurons 62 FISH fluorescence 62 melanin synthesis 62 atrioventricular 62 leukocyte recruitment 62 transporter proteins 62 protein electrophoresis 62 striated muscle 62 TOP2A gene 62 BMP4 62 cardiac fibroblasts 62 antisense molecules 62 colony stimulating factor 62 Leydig cells 62 trabecular 62 gene amplification 62 sequence homology 62 Leukocyte 62 Conjugated 62 SH2 domain 62 Polymerase 62 proteinases 62 retroviral infection 62 cardiolipin 62 muscarinic receptors 62 Histone deacetylase 62 thermodynamic stability 62 leiomyomas 62 hyperintensity 62 HER2 HER3 62 Inosine 62 ankyrin repeat 62 hypothalamic pituitary adrenal HPA 62 cyto 62 computed tomographic 62 PML RARA 62 transcriptional activation 62 pyruvate kinase 62 dimerization 62 Fig. 3b 62 cyclic nucleotide 62 hydrolytic 62 Proteostasis Network 62 cholesterol biosynthesis 62 chaperone proteins 62 intestinal mucosal 62 potentiation 62 morphogen 62 cyclic adenosine monophosphate 62 carboxyl terminal 62 act synergistically 62 xenograft tumors 62 evolutionarily conserved 62 adrenocortical 62 NFκB 62 selectively inhibited 62 GLI1 62 thymocyte 62 diffusible 62 nociceptive 62 membrane permeability 62 histone methylation 62 AMPA receptor 62 Prostaglandin 62 neoplastic transformation 62 IGFBP2 62 acyl CoA 62 Cytotoxicity 62 cadherin 62 beta1 integrin 62 intronic 62 electrophysiologic 62 Platelet Derived Growth 62 fatty acid oxidation 62 methylated DNA