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(Click for frequent words.) 62 SCID mice 61 mice lacking 61 bone marrow stromal cells 60 transgenic mice expressing 60 experimental autoimmune encephalomyelitis 60 mdx mice 59 M1 muscarinic 59 glutamate transporters 59 C#BL 6 59 C#BL 6 mice 59 EGFP 59 SOCS3 59 induced apoptosis 59 TrkB 59 P2X 59 BALB c 58 Myostatin 58 JAK2 enzyme 58 μ opioid receptor 58 experimentally induced 58 transgene expression 58 condensin 58 constitutively active 57 FKBP# 57 phosphorylates 57 BMAL1 57 beta subunit 57 leptin receptor 57 SUMOylation 57 neuroD2 57 antiapoptotic 57 Gly 57 posterior cingulate 57 NR2B subunit 57 PIP2 57 Histone 57 Rap1 57 BDNF gene 57 hippocampal neurons 57 cytidine 56 db db mice 56 coexpression 56 subcellular localization 56 activated macrophages 56 somatostatin 56 syngeneic 56 BMP signaling 56 adrenoceptor 56 GLUT4 56 GlcNAc 56 p#NTR 56 FGFR4 56 adenylyl cyclase 56 Hcrt 56 apo AI 56 dynactin 56 cytosolic 56 dorsal root 56 Dystrophin 56 presynaptic 56 Cytochrome 56 AMACR 56 transferase 56 microglial 56 C1q 56 cytochrome 56 hepatoma 56 muscarinic receptors 56 pDC 56 EP4 56 beta adrenergic receptors 56 Nf1 55 transgenic mouse model 55 UCP2 55 CaM 55 BALB c mice 55 CEACAM1 55 p# alpha [001] 55 CpG ODN 55 γδ T cells 55 xanthine oxidase 55 ERK signaling 55 capillary endothelial cells 55 mutant mice 55 alpha4 55 CD8 + 55 glutamyl 55 LDLR 55 HepG2 cells 55 6 OHDA 55 wildtype 55 adipogenic 55 STAT4 55 BCL#A 55 glutamatergic 55 ortholog 55 thymosin 55 TEL AML1 55 Akt phosphorylation 55 siRNA knockdown 55 ligand receptor 55 spinous 55 methyltransferase 55 IKKß 55 TRIM5 55 KLF4 55 ectopic expression 55 PDGFR 55 ChR2 55 HIF 1a 55 transduced 55 heterozygotes 55 cysteines 55 Fas ligand 55 cultured neurons 55 GHRH 55 ribosomal protein 55 cholecystokinin CCK 55 transgenic mouse models 55 receptor blocker 55 amylin 55 transient transfection 54 MDR1 54 TGF ß 54 ob ob mice 54 p#Kip# 54 IL 1beta 54 isomerase 54 ouabain 54 Dysregulation 54 ERK1 2 54 antiproliferative activity 54 S#K# 54 protein tyrosine phosphatase 54 alpha2 54 glucose transporter 54 COL#A# 54 null mice 54 interferon IFN 54 motoneurons 54 Sirt1 54 NR1 54 JAK STAT 54 myocytes 54 catenin 54 selectively binds 54 Phosphorylation 54 alveolar epithelial cells 54 IgG1 54 NF κB activation 54 ERK pathway 54 antisense inhibition 54 cyclin E 54 cyclin dependent kinase inhibitor 54 ESR1 54 splenocytes 54 Overexpression 54 glycosyltransferase 54 AMPA receptor 54 LRAT 54 ovariectomized 54 immunofluorescence staining 54 C#BL/#J 54 receptor subunit 54 nucleolin 54 lysates 54 locomotor activity 54 striatal 54 enterocytes 54 Rab5 54 CpG island 54 transcriptional repressor 54 ER alpha 54 Ca2 + 54 superoxide dismutase 54 cortical neurons 54 IGFBP2 54 D2 receptors 54 mRNA expression 54 c fos 54 PTHrP 54 morphogen 54 transgenic mice 54 IGFBP 3 54 glucocorticoid 54 Oncogenic 54 transiently transfected 54 ERa 54 oligomerization 54 1alpha 53 exendin 4 53 colony stimulating factor 53 homozygote 53 osteoblast 53 secretory 53 intraperitoneal injection 53 male Sprague Dawley 53 Catenin 53 Immunohistochemical analysis 53 Fig. 3a 53 CXCL# 53 PC# cells 53 cyclophilin D 53 neurotrophin 53 inhibitory 53 CD#c 53 lipid accumulation 53 Transgenic Mice 53 Polymorphism 53 PPARγ 53 overexpressing 53 HEK# cells 53 TLR2 53 Leydig cells 53 beta1 53 Jhdm2a 53 receptor inhibitor 53 TNFalpha 53 Kir#.# 53 neurite outgrowth 53 cell adhesion molecule 53 streptozotocin 53 anterior pituitary 53 adipocyte 53 kinesin motor 53 paxillin 53 serpin 53 nNOS 53 immunostimulatory 53 Cx# [001] 53 CD# CD# 53 IFNg 53 deficient mice 53 embryonal carcinoma 53 Wnt1 53 leptin signaling 53 oncogenic transformation 53 H#K#me# 53 neurofilament 53 #p# [003] 53 hepatocyte 53 isoenzymes 53 gag pol 53 pRb 53 serine threonine kinase 53 hydroxylase 53 MAP kinase 53 PARP1 53 proapoptotic 53 TRPV4 53 Herpes virus 53 cynomolgus monkeys 53 autoreactive 53 Fig. 1C 53 mRNA encoding 53 C EBP alpha 53 MEK1 53 p# MAPK 53 p# deficient 53 interferon pathway 53 tyrosine hydroxylase 53 eNOS 53 NF1 gene 53 beta tubulin 53 UCP1 53 IL 1β 53 prion protein PrP 53 Hippocampus 53 inhibitory receptor 53 cells transfected 53 cardiac fibroblasts 53 isoenzyme 53 constitutively expressed 53 TGF ß1 53 lymphoid cells 53 Purkinje cell 53 Subunit 53 OCT4 53 Hh 53 acyltransferase 53 metabolizing enzyme 53 CTLs 53 SMN1 53 androgen receptor AR 53 Sgk1 53 murine 53 Nampt 53 Src kinases 53 Mice deficient 53 vascular endothelial cells 52 proximal tubule 52 homodimer 52 esterase 52 globin 52 adenosine receptor 52 IGF1R 52 GH secretion 52 PTP1B 52 vomeronasal 52 oxytocin receptor 52 xenograft tumors 52 MT1 MMP 52 IKK2 52 glutathione S transferase 52 Purkinje cells 52 PU.1 52 Mice lacking 52 retinal neurons 52 histone H3 52 lipopolysaccharide 52 C#T [002] 52 Tg# [002] 52 valine 52 potentiation 52 ß1 52 hormone adiponectin 52 aspartyl 52 miRNAs miR 52 lysophosphatidic acid 52 junctional 52 acetylcholine receptor 52 Razer Mamba 52 overexpressing cells 52 endothelial nitric oxide synthase 52 Germline 52 colocalization 52 unmutated 52 FABP 52 V#E 52 covalently attached 52 calcineurin 52 LNCaP cells 52 nicotinic receptor 52 globin genes 52 RAR beta 52 homolog 52 immunoreactivity 52 neuronal synapses 52 fibulin 52 TGF beta1 52 Reductase 52 melanocyte stimulating hormone 52 TH1 52 fibrogenesis 52 E cadherin 52 suppressor gene 52 activin 52 pineal 52 SOD1 protein 52 glycosylated 52 STAT1 52 RNA polymerases 52 P0 52 hormone angiotensin II 52 mu receptors 52 MyD# 52 LNCaP 52 4E BP1 52 IGF2 52 ubiquitylation 52 Sonic Hedgehog 52 Galectin 52 mutant mouse 52 amino terminus 52 hydroxylation 52 molecular scissors 52 calpain 52 glutamate receptor 52 decarboxylase 52 Sp1 52 estrogen receptor alpha 52 BMP4 52 Androgen receptor 52 Foxp3 52 SMAD4 52 heme oxygenase 1 52 exonuclease 52 caveolin 1 52 adenomatous polyposis coli 52 receptor tyrosine kinase 52 Nedd4 52 peptide receptor 52 cofilin 52 CD#b 52 demyelinated 52 CHD5 52 obese diabetic NOD 52 mitogen activated protein kinases 52 TMEM#B 52 Wnt signaling 52 MMP2 52 airway hyper responsiveness 52 c myc 52 mitogenic 52 deletion mutant 52 PrP 52 ErbB4 52 tiny roundworm 52 furin 52 lacZ 52 cisplatin resistant 51 CDK4 51 telomerase gene 51 TRAIL induced apoptosis 51 mice 51 serotonin transporter 51 hyperactivation 51 MEFs 51 Or#b 51 microRNA #a 51 CCR5 receptors 51 PGC 1α 51 cholinergic receptors 51 Figure 1A 51 receptor activation 51 heterologous 51 telomerase reverse transcriptase 51 cardiac myocytes 51 cytoplasmic domain 51 adipose cells 51 Microtubule 51 mu opioid receptor 51 transfected 51 Shp2 51 cellulose synthase 51 synaptic proteins 51 tyrosine phosphorylation 51 transgenic rats 51 CB1 receptors 51 DU# [002] 51 receptor antagonism 51 adrenal cortex 51 Prostaglandin 51 matrix metalloproteinase 51 keratins 51 TSC2 51 NFkB 51 histone H4 51 Hsp# [001] 51 KLF# 51 c KIT 51 TGF β1 51 vacuolar 51 MnSOD 51 Nanog 51 phosphorylate 51 metalloproteinase 51 Integrin 51 globin gene 51 potent inhibition 51 Drosha 51 HFE gene 51 Upregulation 51 stellate cells 51 melanocyte 51 TGF β 51 noncoding RNA 51 activated protein kinase 51 immunized mice 51 knockout mice 51 p# p# 51 TCF4 51 transgenic zebrafish 51 adhesion molecule 51 Sonic hedgehog 51 phosphoinositide 51 transmembrane protein 51 Cytotoxic T 51 GAPDH 51 autophagic 51 transcriptional activator 51 syntaxin 51 planaria 51 podocytes 51 genetically altered mice 51 aminopeptidase 51 NKT cell 51 preadipocytes 51 gene encodes protein 51 postsynaptic 51 Dopaminergic 51 mediated phosphorylation 51 VP1 51 dopaminergic neurons 51 E#F# 51 mutant allele 51 vasopressin receptors 51 Notch1 51 Bcl xL 51 transcriptional activation 51 CaMKII 51 budding yeast 51 inducible 51 arcuate nucleus 51 gene inactivation 51 5 HT1A 51 hTERT 51 HuR 51 fig. S2 51 β catenin 51 amino terminal 51 Sandhoff disease 51 transmembrane receptor 51 creatine kinase CK 51 P#S 51 xenograft model 51 SIRT6 51 DGAT1 51 orexin receptors 51 HepG2 51 GABAergic neurons 51 beta globin 51 myo inositol 51 LDL receptor 51 mesolimbic 51 mPGES 1 51 ERK2 51 protein p# 51 BRAF V#E 51 Bcl 51 coactivator 51 hippocampal 51 phagocytosis 51 neural cells 51 asymmetric multiprocessing 51 recessive mutation 51 p# mitogen activated 51 HERV 51 receptor subtypes 51 granule cells 51 luteolin 50 microtubule associated 50 pancreatic islet 50 toxic beta amyloid 50 muscarinic receptor 50 substrate specificity 50 apoE 50 PrPC 50 TIMP 1 50 MDMX 50 kappa opioid receptor 50 Hypoxia Inducible Factor 50 iNOS 50 PBMCs 50 pluripotency genes 50 glucocorticoid receptors 50 skin fibroblasts 50 dopamine synthesis 50 olfactory receptor neurons 50 phospholipase 50 inbred strains 50 hMSCs 50 TRAF6 50 Fig. 4a 50 Fig. 3b 50 glucokinase 50 trophoblast cells 50 Cdx2 50 leptin deficient 50 intronic 50 serotonin receptor 50 VSV G 50 dopamine signaling 50 proline rich 50 Macrophage 50 mitogen activated protein 50 XPB 50 MAPK 50 breast epithelial cells 50 TRAF1 50 CD8 T cell 50 CRF1 receptor 50 prodynorphin 50 MSNs 50 Smad3 50 costimulatory 50 Tie2 50 androgen receptor gene 50 leptin receptors 50 MMP9 50 vesicular stomatitis virus 50 MC4R gene 50 constitutively 50 weekly subcutaneous injections 50 Haplotype 50 downregulation 50 reductase 50 Macaca mulatta 50 occludin 50 mutant proteins 50 mitogen activated protein kinase 50 overexpress 50 intracellular signaling 50 RCAN1 50 downregulated 50 Figure S4 50 mitogen 50 metalloproteinases 50 atypical neuroleptics 50 osteocalcin 50 dopamine receptor 50 telomere dysfunction 50 Polymerase 50 homozygotes 50 malonyl CoA 50 genetically modified mice 50 utrophin 50 Wistar rats 50 Leukotriene 50 hippocampal cells 50 TAp# 50 monocyte 50 GPR# [002] 50 regulated kinase ERK 50 FoxO1 50 defensin 50 RNA Polymerase 50 Irs2 50 palytoxin 50 PIP3 50 Supplemental Figure 50 colorectal tumor 50 Dictyostelium 50 survivin 50 PPARgamma 50 CD1d 50 Nucleic Acids Res 50 NKX#.# 50 genetically engineered mouse 50 skeletal muscle cells 50 glucocorticoid receptor 50 tumor suppressor protein 50 CHO K1 50 pyruvate kinase 50 mTORC1 50 carcinoembryonic antigen 50 GPR# [001] 50 uPA 50 POMC neurons 50 ob ob 50 serotonergic 50 COOH terminal 50 integrin alpha 50 Fig. 3A 50 operon 50 gene polymorphism 50 cortical plasticity 50 PTEN gene 50 receptor gene 50 tyrosine kinase receptor 50 receptor kinase 50 gene encodes 50 fruitfly Drosophila 50 Wnt protein 50 zebrafish embryo 50 peptidase 50 RASSF1A 50 anaphase promoting complex 50 GSTT1 50 c Myc 50 GTPase 50 fibronectin 50 G#A [002] 50 CXCR2 50 GLUT1 50 OGG1 50 matrix metalloproteinases MMPs 50 aggregated Abeta 50 prostate epithelial cells 50 actin polymerization 50 eotaxin 50 RUNX3 50 MAPK pathway 50 uncoupling protein 50 polyamine 50 nucleoside nucleotide 50 fluorescently tagged 50 Phenotyping 50 Interferon gamma 50 SH2 B 50 SIRT1 gene 50 eIF2 50 gibbon ape 50 cAMP 50 Mutant mice 50 C#Y 50 Kv#.# 50 heterozygous 50 HSF1 50 Neural stem cells 50 GRK2 50 amino acid alanine 50 CB2 receptor 50 bacterium Escherichia coli 50 induced pluripotent cells 50 Deadlinepix 50 demethylase 50 Hh pathway 50 rod photoreceptors 50 homologous 50 costimulatory molecules 49 cells overexpressing 49 carboxylase 49 TET2 49 inosine 49 transferrin receptor 49 protein encoded 49 circulating lymphocytes 49 Neuregulin 1 49 thymidine kinase 49 COX2 49 humanized mice 49 focal adhesion 49 promoter polymorphism 49 phagocyte 49 ß amyloid 49 allergic airway inflammation 49 MEF2A 49 TG2 49 mRNA transcripts 49 TLR3 49 forelimb 49 SHANK3 49 coding genes 49 HDAC2 49 T#M 49 5HT 49 PD# [005] 49 phosphate dehydrogenase 49 MEK ERK 49 glycan binding 49 aP2 49 MeCP2 49 lyase 49 Gln 49 PDZ domain 49 cystic fibrosis transmembrane conductance 49 synthetase 49 antigenic epitopes 49 Brain derived neurotrophic 49 E1A 49 follistatin 49 epigenetically 49 stathmin 49 gene p# 49 cAMP dependent 49 TGF beta pathway 49 T#A [001] 49 insulin receptors 49 Flt3 49 transcriptional regulation 49 NFAT 49 beta1 integrin 49 pulvinar 49 stably expressing 49 cathepsin B 49 chemokine receptor 49 Fig. 2C 49 cytochrome b 49 gene encoding 49 PGC1 49 telomere maintenance 49 dopamine neurons 49 excitatory 49 glioma cells 49 brown adipose tissue 49 effector protein 49 EGF receptor 49 thymocyte 49 nicotinamide 49 piRNAs 49 transthyretin 49 acinar cells 49 Mus musculus 49 extracellular domain 49 ApoE 49 Klf4 49 mouse embryonic fibroblasts 49 HIF 1alpha 49 Notch receptor 49 Vpr 49 downstream effector 49 annexin 49 TNFa 49 myostatin gene 49 Uch L1 49 IIIc 49 carboxypeptidase 49 caspase activation 49 myocyte enhancer factor 49 MDM2 49 endogenous retrovirus 49 Myb 49 acetylcholinesterase 49 myogenesis 49 rat neurons 49 Frizzled 49 neuron degeneration 49 biotinylated 49 S#A# [002] 49 proteolysis 49 fission yeast 49 neuropeptide Y 49 cyclooxygenase 49 receptor signaling 49 neuropeptide 49 dystroglycan 49 ribonucleic acid molecules 49 stromal derived 49 cadherin 49 Olig2 49 muscarinic 49 processive 49 PTEN protein 49 extracellular signal 49 CD# + [001] 49 SIRT1 protein 49 zebrafish embryos 49 TrkA 49 PON1 49 S. cerevisiae 49 telomeric 49 Neuronal 49 Foxp2 49 Arf gene 49 exocytosis 49 hypoxia induced 49 Figure 1C 49 variant allele 49 ß 49 Cyclin 49 EBNA1 49 FGF2 49 Rho GTPase 49 xenografts 49 MDCK cells 49 p# activation 49 HOTAIR 49 IL2 49 mutant worms 49 lactamases 49 K#N 49 PTPN# 49 thymidylate synthase TS 49 PGCs 49 glutamate receptors 49 connexin 49 Caveolin 1 49 mice genetically altered 49 claudin 49 endonuclease 49 ENaC 49 Apolipoprotein 49 adult neurogenesis 49 VEGF receptor 49 stathmin gene 49 soluble receptor 49 excitatory synapses 49 Fig. 1b 49 Notch signaling 49 cyclic AMP 49 eIF4E 49 GTP hydrolysis 49 CatB 49 Stat1 49 APOC3 49 NFKBIA 49 AG# [002] 49 coding exons 49 corticosterone 49 DRD2 49 PrPSc 49 epithelial stem cells 49 NMDA receptors 48 Ribosomal 48 diabetic rats 48 H#K# [002] 48 SIR2 gene 48 trypanosome 48 HDAC6 48 phosphatidylinositol 48 goblet cells 48 isoforms 48 bispecific 48 neuroblastoma cells 48 Cytoplasmic 48 Fig. 1D 48 Schematic diagram 48 5 hydroxytryptamine 48 tumor suppressor PTEN 48 NOD mice 48 hind paw 48 NFκB 48 IGF1 48 viral capsid 48 apoptosis pathway 48 PGE2 48 calcium calmodulin dependent 48 mammary gland tumors 48 intercellular adhesion molecule 48 NKG2D 48 dephosphorylation 48 mutant p# 48 PC3 cells 48 PECAM 1 48 regulated kinase 48 PINK1 48 miR #a [002] 48 electrically stimulated 48 induces apoptosis 48 constitutively activated 48 GH IGF 48 paternally inherited 48 intergenic regions 48 MDA MB 48 mutant mice lacking 48 NRG1 48 ODNs 48 Sirt3 48 microelectrode 48 prion protein gene 48 vasopressin receptor 48 methylation patterns 48 gp# protein [002] 48 cannabinoid receptors 48 NS3 48 transfected cells 48 sonic hedgehog 48 GSTM1 48 PPARg 48 transfer RNA tRNA 48 thrombospondin 48 genetically altered mouse 48 meiotic recombination 48 elastase 48 glutamate signaling 48 μg ml 48 thioredoxin 48 diabetic mice 48 gB 48 Fig. 1a 48 RecA 48 ZP3 48 Cell Receptor 48 BOULE 48 Fig. 2B 48 heterochromatic 48 neural progenitor 48 At#g# 48 neural progenitor cells 48 X#L 48 neprilysin 48 Rhesus Macaque 48 HCV replication 48 MEF2 48 neutrophil 48 luciferase reporter 48 ribonucleotide reductase 48 homologue 48 missense mutation 48 A#V 48 DNMT1 48 Rb protein 48 Vps# 48 homodimers 48 cell receptor TCR 48 inhibitory effect 48 intestinal epithelial cells 48 Xenograft 48 modulatory 48 figs. 48 ^ sup #m 48 alanine 48 mesoderm 48 dystrophin gene 48 dopamine receptors 48 gp# [002] 48 brain derived neurotrophic 48 E3 ubiquitin ligase 48 hemagglutinin H 48 ATPases 48 hnRNP 48 N. benthamiana 48 G9x 48 Schwann cells 48 fibroblast cells 48 experimentally infected 48 EGFR signaling 48 CCR7 48 isoleucine 48 HCT# 48 serine protease 48 enzymatic activity 48 ghrelin receptor 48 primordia 48 differentially regulated 48 SGS# 48 NFATc1 48 EP1