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(Click for frequent words.) 79 ERK1 2 78 Smad3 77 MAP kinase 77 TGF beta1 77 FGFs 77 tyrosine phosphorylation 77 autophagic 77 overactivation 77 TGF b 76 IFN γ 76 proapoptotic 76 ERK signaling 76 Treg cell 76 prostaglandin synthesis 76 Hedgehog signaling 76 TGF ß 76 TGF β 76 synaptogenesis 76 Fas ligand 75 antiapoptotic 75 RAS RAF MEK 75 TNFalpha 75 MAPK pathway 75 activin 75 caveolin 1 75 c MYC 75 SIRT2 75 Rab5 75 cathepsins 75 cyclic AMP cAMP 75 NFκB 75 renal fibrosis 75 intracellular signaling 75 eNOS 75 EGF receptor 75 cell adhesion molecules 75 lymphangiogenesis 74 intracellular signal transduction 74 thioredoxin 74 PHD2 74 β catenin 74 receptor tyrosine kinase 74 mitogen activated protein kinase 74 immunoregulatory 74 histone acetylation 74 BMP signaling 74 Notch signaling 74 pro angiogenic 74 hyperactivation 74 mitogenic 74 Clusterin 74 Fc receptor 74 FKBP# 74 ACh 74 HDAC6 74 IL 1beta 74 p# MAPK 74 proteolysis 74 HIF 1α 74 miR# 74 neurotrophic 74 p# activation 74 synaptic transmission 74 γ secretase 74 NKG2D 74 MT1 MMP 74 cAMP signaling 74 Jhdm2a 74 Akt activation 74 mediated inhibition 74 synapse formation 74 Wnt signaling 74 CEACAM1 74 costimulatory 73 signaling cascades 73 nitric oxide synthase 73 tumorigenicity 73 mitochondrial respiration 73 p#Kip# 73 intestinal epithelium 73 ADAMTS# 73 transgene expression 73 P cadherin 73 SOCS3 73 intercellular signaling 73 deacetylation 73 microglial 73 melanocyte 73 cytokine signaling 73 microtubule dynamics 73 4E BP1 73 Cathepsin B 73 PDGFR 73 Lyn kinase 73 TGF ß1 73 TGF beta pathway 73 paxillin 73 cell motility 73 miR #a [002] 73 pRb 73 PPARg 73 AT1R 73 GLI1 73 GRP# 73 CD1d 73 ß catenin 73 protein kinase C 73 neuronal signaling 73 Htt 73 HepG2 cells 73 TGF beta signaling 73 Notch1 73 Th2 cytokines 73 catenin 73 ERK phosphorylation 73 FasL 73 vascular endothelial cells 73 IL 1β 73 uPAR 73 Wnt signaling pathway 73 LRP5 73 NKT cell 73 paracrine 73 neuronal differentiation 73 transcriptional repressor 73 lymphocyte activation 73 epithelia 72 PPARγ 72 p#NTR 72 PC# cells 72 cholesterol homeostasis 72 NF κB 72 secretory pathway 72 cyclic AMP 72 IRE1 72 osteoblast 72 Foxp3 72 podocytes 72 N cadherin 72 microglial activation 72 myofibroblast 72 serine threonine kinase 72 neuronal dysfunction 72 thymidylate synthase TS 72 TNF α 72 granzyme B 72 isoenzymes 72 mTORC1 72 posttranslational modification 72 PTPN# 72 constitutively active 72 FGF2 72 autocrine 72 eicosanoid 72 sphingolipid 72 ERK pathway 72 selective inhibition 72 E#F# 72 MAP kinases 72 Nod1 72 Androgen receptor 72 axon guidance 72 keratinocyte 72 effector functions 72 neuronal plasticity 72 osteoclast formation 72 HOTAIR 72 serine threonine 72 NKX#.# 72 Nedd4 72 NFkappaB 72 extracellular signal 72 HuR 72 tryptase 72 adipogenic 72 BCL#A 72 c myc 72 haematopoietic 72 DNA demethylation 72 androgen receptor AR 72 oncogenic transformation 72 IGF1R 72 HIF 1alpha 72 HDAC2 72 erythropoiesis 72 oncoprotein 72 focal adhesions 72 Src kinase 72 caveolin 72 c Myc 72 inflammatory cytokine 72 Prox1 72 cyclin B1 72 Eg5 72 Sgk1 72 AMPA receptor 72 transcriptional regulation 72 UCP2 72 cardiac fibroblasts 72 Wnt beta catenin 72 HCV replication 72 TGF β1 72 cyclins 72 BCL2 72 somatostatin 72 mesenchymal cell 72 enzymatic activity 72 HIF 1a 72 Akt1 72 p# alpha [001] 72 intracellular proteins 72 BMP4 72 LKB1 72 M1 muscarinic 72 proto oncogene 72 prostaglandin E2 PGE2 72 Wnts 72 E cadherin expression 71 cellular pathways 71 hypothalamic pituitary 71 ERK2 71 EphB2 71 MAPK 71 spermidine 71 effector function 71 IL 1ß 71 prostaglandin E2 71 CD# expression [001] 71 ectopic expression 71 cyclic adenosine monophosphate cAMP 71 TAp# 71 NF kB pathway 71 transcriptional activation 71 TNFa 71 transthyretin 71 calpain 71 oncomodulin 71 Rap1 71 Neuropeptide Y 71 pDC 71 adhesion molecule 71 SGK1 71 endogenous ligands 71 F actin 71 tumorigenesis 71 MMP9 71 JAK2 enzyme 71 steroidogenic 71 matrix metalloproteinases 71 humoral immunity 71 neurite 71 glutamate receptors 71 inhibitory effects 71 proteoglycan 71 EZH2 71 glycosyltransferase 71 Tie2 71 beta adrenergic receptors 71 Upregulation 71 acetylcholine receptor 71 GPx 71 VEGF receptor 71 histone modifications 71 chromosome condensation 71 ERK activation 71 Phosphorylation 71 adipocyte 71 neurotransmitter glutamate 71 Notch pathway 71 PTHrP 71 peroxisome 71 cardiolipin 71 p# MAP kinase 71 XBP1 71 cyclophilin D 71 PIP2 71 TNFR 71 ubiquitylation 71 GABAergic 71 GABAA receptors 71 podocyte 71 IL #p# 71 coexpression 71 messenger molecule 71 HSF1 71 serine protease 71 osteoblastic 71 GABAergic interneurons 71 transmembrane receptor 71 histone deacetylases 71 RhoA 71 EphA2 71 FUS1 71 apoptotic pathway 71 TGFbeta 71 tumor microenvironment 71 Th1 type 71 adipokines 71 JAK STAT 71 calcineurin 71 Aâ 71 regulated kinase ERK 71 Stat1 71 IL6 71 PI3K Akt 71 glutamatergic 71 ERK1 71 ENaC 71 ubiquitination 71 upregulates 71 CCL# 71 phosphorylates 71 ß amyloid 71 phosphatidylinositol 3 71 fatty acid oxidation 71 glutamate signaling 71 leukocyte recruitment 71 endothelial nitric oxide synthase 71 miR #a [001] 71 STAT3 signaling 71 amyloid β 71 PGE2 71 immunoreactivity 71 radiosensitivity 71 synovial cells 71 chromatin structure 71 hyperactivated 71 Hh pathway 71 superoxide dismutase 71 PIP3 71 actin cytoskeleton 71 Vascular endothelial growth 71 EGFR signaling 71 TrkB 71 cell adhesion molecule 71 modulatory 71 Cyclin D1 71 VEGFR1 71 upregulating 71 basophils 71 oligomerization 71 T lymphocyte 71 SCD1 71 GluR1 71 isotypes 71 downstream effectors 71 ABCA1 71 homodimers 71 IFN gamma 71 Flt3 71 osteoclast 71 ß1 71 adult neurogenesis 71 oncogenesis 71 COX enzymes 71 sGC 71 fibroblast 71 apoE 70 excitatory neurotransmitter glutamate 70 TXNIP 70 PGC 1α 70 c MET 70 CTGF 70 costimulation 70 FGF signaling 70 nAChR 70 protein tyrosine kinase 70 cytoprotective 70 TMEM#B 70 TRAIL induced apoptosis 70 TRPV4 70 cyclooxygenase 2 70 LRP6 70 phagocytosis 70 morphogen 70 anterior pituitary 70 tumor suppressor protein 70 neurofibromin 70 STAT1 70 Bcl xL 70 agonist induced 70 sortilin 70 NF kappaB activation 70 thymocyte 70 LPS induced 70 endoplasmic reticulum stress 70 MMP2 70 TGF alpha 70 Angiotensin converting enzyme 70 Akt signaling 70 anti apoptotic 70 lipid synthesis 70 polyamine 70 micro RNAs 70 arginase 70 tyrosine kinase 70 anti inflammatory cytokine 70 glucose transporter 70 eotaxin 70 cholesterol biosynthesis 70 cholecystokinin CCK 70 Oncogenic 70 hedgehog pathway 70 caspase activation 70 constitutively expressed 70 osteogenic 70 cypin 70 mTOR signaling 70 mRNA encoding 70 adrenoceptor 70 antibody mediated 70 proinflammatory 70 protein tyrosine phosphatases 70 Dpp 70 macrophage activation 70 TGFß 70 Runx2 70 neuromuscular junction 70 monocytes macrophages 70 C EBP alpha 70 dephosphorylation 70 LIS1 70 GLUT4 70 GPR# [002] 70 receptor gamma 70 phosphorylate 70 glial cell 70 IKK2 70 astrocytic 70 ATPase activity 70 exocytosis 70 CD#c 70 secretase 70 KLF2 70 potent inhibition 70 isoenzyme 70 JNK1 70 calcium homeostasis 70 C1q 70 inhibitory activity 70 cyclin E 70 FGFR3 70 inducible nitric oxide synthase 70 interleukin 1beta 70 mutant huntingtin protein 70 cathepsin B 70 FOXP3 70 thyrotropin 70 CagA 70 Smoothened 70 eIF4E 70 downregulation 70 iNOS 70 motoneurons 70 lung epithelium 70 glucocorticoid receptor 70 NO synthase 70 HBx 70 cytosolic 70 lysosomal 70 mevalonate 70 osteoclast activity 70 mitogen 70 hippocampal neurons 70 c Src 70 receptor activation 70 nitrotyrosine 70 IGF IR 70 mRNA expression 70 constitutively 70 glucokinase 70 innate immune responses 70 beta arrestin 70 fibrogenesis 70 GABAB receptors 70 interferon γ 70 mitogen activated protein kinases 70 NR2B 70 EGFr 70 protein tyrosine phosphatase 70 prostate epithelial cells 70 acinar 70 VEGF expression 70 PI3K signaling 70 cystic fibrosis transmembrane conductance 70 hematopoiesis 70 neurotransmitter GABA 70 metalloproteinase 70 VE cadherin 70 muscarinic receptors 70 IgG4 70 serine proteases 70 phosphoinositide 70 gastrin 70 factor HGF 70 MAPKs 70 NR2B subunit 70 glycosylated 70 Kv#.# 70 dimerization 70 neurotransmitter receptor 70 RANK Ligand 70 matrix metalloproteinases MMPs 70 epigenetic mechanisms 70 STIM1 70 subcellular compartments 70 extracellular dopamine 70 SIRT1 gene 70 epithelial cells lining 70 LTB4 70 galectins 70 presynaptic 70 #ß 70 mitochondrial enzyme 70 downregulate 70 estrogen receptor alpha 70 tropomyosin 70 Dopaminergic 69 PI3K AKT 69 IFNg 69 induce apoptosis 69 ERBB2 69 FGFR1 69 phospholipase 69 GAPDH 69 genotoxic stress 69 enzymatic pathways 69 histone modification 69 RRM1 69 proinflammatory cytokines 69 proteolytic cleavage 69 histone methylation 69 PKC isoforms 69 myogenesis 69 stem cell pluripotency 69 Wnt1 69 cardiac myocytes 69 cellular prion protein 69 Rho GTPases 69 huntingtin 69 polyadenylation 69 tumor suppressive 69 Notch receptor 69 Aß 69 SOCS1 69 cytolytic 69 receptor subtypes 69 membrane receptors 69 phosphate S1P 69 Protein Kinase C 69 habenula 69 MDR1 69 microRNAs miRNAs 69 COX2 69 SH2 B 69 PPAR γ 69 glomerular 69 EGF receptors 69 nAChRs 69 GSK3 69 β1 69 5 HT2A serotonin 69 Shh signaling 69 Th2 69 glycolipids 69 Wnt proteins 69 antiproliferative activity 69 NMDAR 69 fast skeletal troponin 69 cytokine receptor 69 vimentin 69 V#F mutation 69 mitotic progression 69 chromatin remodeling 69 Abeta# 69 metalloprotease 69 transgenic mice expressing 69 vasodilatation 69 cytokines IL 69 myocyte 69 bone morphogenetic proteins 69 cytochrome c 69 Th1 cells 69 proinflammatory cytokine 69 protein phosphorylation 69 basic fibroblast 69 Wnt pathway 69 DNA methylation patterns 69 PDGF receptor 69 tumor antigen 69 monocyte 69 telomere dysfunction 69 cyclin D1 69 PI3 kinase 69 serotonin receptor 69 leukemic cell 69 Notch signaling pathway 69 biogenesis 69 malignant prostate 69 SMAD4 69 alpha subunit 69 induced apoptosis 69 lymphoid cells 69 actin binding 69 secretory 69 CDK5 69 CXCL# 69 focal adhesion kinase FAK 69 redox active 69 chondrocyte 69 amyloid deposition 69 S#A# [002] 69 posttranslational modifications 69 GATA3 69 ERa 69 transmembrane protein 69 kinase pathway 69 mRNA translation 69 Cytotoxic T 69 Th1 Th2 69 pancreatic islet 69 ligand TRAIL 69 intracellular calcium 69 TGFβ 69 S1P 69 BubR1 69 adrenal cortex 69 serotonin synthesis 69 siRNA knockdown 69 protein tyrosine phosphatase 1B 69 SIRT3 69 ER alpha 69 degranulation 69 synuclein 69 neuropeptide Y NPY 69 polycystin 69 acyl CoA 69 microvascular endothelial cells 69 HER2 neu 69 axonal degeneration 69 myofibroblasts 69 EGFR protein 69 cyclic adenosine monophosphate 69 microRNA molecules 69 antitumor efficacy 69 AMPA receptors 69 CaM kinase II 69 cytokine 69 Skp2 69 MDSCs 69 mRNA decay 69 NF KB 69 downregulating 69 progranulin 69 tenascin C 69 c Fos 69 Fibroblast Growth Factor Receptor 69 Pten 69 SUMOylation 69 upregulation 69 #HT#A 69 signal transduction pathway 69 hepatoma 69 tyrosine hydroxylase 69 Neurogenesis 69 gliosis 69 IGFBP2 69 subcellular localization 69 RKIP 69 oxidative phosphorylation 69 ligand induced 69 downregulates 69 regulating gene expression 69 brain derived neurotrophic 69 structural rearrangements 69 biologic pathway 69 carcinoembryonic antigen 69 CYP#B# 69 Nampt 69 pyruvate kinase 69 HDACs 69 FOXO3a 69 sequence homology 69 Mcl 1 69 E3 ubiquitin ligase 69 lymphotoxin 69 transcriptional regulators 69 alveolar epithelial cells 69 PDGFR alpha 69 axonal 69 ligases 69 intercellular communication 69 interleukins 69 eIF2 69 neuronal cell 69 Akt phosphorylation 69 Rb#/p# 69 PU.1 69 neuropeptides 69 S nitrosylation 69 MEK ERK 69 CCR7 69 FGF# 69 chemokine receptor 69 glioma cells 69 Histone deacetylase 69 renal tubular 69 mediated apoptosis 69 primary cilia 69 IL #R 69 DNMT1 69 osteogenic differentiation 69 protein conformation 69 FLT3 69 apoptotic 69 protein p# 69 pro apoptotic 69 casein kinase 69 NFkB 69 DGAT1 69 coagulation cascade 69 dynamin 69 cell adhesion 69 homodimer 69 NF kappaB 69 antioxidant enzymes 69 circadian genes 69 hypothalamic pituitary adrenal axis 69 synaptic vesicle 69 virulence genes 69 CB2 receptor 69 TORC2 69 replicase 69 Sirt1 69 osteoblast differentiation 69 transcriptionally 69 immunostimulatory 69 CD#b 69 prostanoid 69 vesicle fusion 69 hepatocyte 69 metabolic enzymes 69 cytokine secretion 69 mutant huntingtin 69 cytoskeletal 69 plasminogen 69 POMC neurons 68 RUNX3 68 activated microglia 68 metalloproteases 68 E cadherin 68 Six3 68 KLF4 68 mTOR pathway 68 Overexpression 68 neuropeptide Y 68 cytoplasmic domain 68 chemotactic 68 cofilin 68 IL #E 68 elastase 68 BDNF protein 68 glutamate neurotransmission 68 pleiotropic 68 basolateral 68 mPGES 1 68 NFKBIA 68 bronchial epithelial cells 68 adaptive immunity 68 SOD1 68 ARF1 68 neuronal apoptosis 68 miRs 68 Sonic hedgehog 68 CD4 + CD# 68 TrkA 68 lymphocyte 68 Aldosterone 68 cyclin dependent kinases 68 receptor signaling 68 cyclooxygenase 68 P selectin 68 cyclooxygenase COX 68 hepatic glucose production 68 CCL5 68 heparanase 68 guanine nucleotide exchange 68 factor PlGF 68 NOD2 68 alpha synuclein protein 68 trophoblast cells 68 transcriptional activity 68 intestinal mucosa 68 oligodendrocyte 68 apoptosis inducing 68 adipose cells 68 cAMP 68 RANKL 68 morphogens 68 hypothalamic 68 Macrophage 68 adenylate cyclase 68 cisplatin resistant 68 hormone secretion 68 superantigens 68 lipoxygenase 68 connexin 68 glycogen synthase kinase 68 endothelial nitric oxide 68 allergic inflammation 68 epigenetic modifications 68 epigenetic alterations 68 receptor alpha 68 PAX5 68 Cyclin E 68 Dysregulation 68 beta subunit 68 PGC1 68 membrane fusion 68 experimental autoimmune encephalomyelitis 68 mutant proteins 68 proton pump 68 NQO1 68 heterodimers 68 ERalpha 68 striatal dopamine 68 PEDF 68 factor GDNF 68 #T# L1 68 FOXO 68 IgG1 68 trophoblasts 68 myeloid cells 68 CD# ligand 68 tumor suppressor PTEN 68 GABAergic neurons 68 neovascularization 68 stromal cells 68 STAT3 68 NMDA receptor 68 TET2 68 secreted protein 68 postsynaptic 68 PPARgamma 68 Rac1 68 TGFb 68 non coding RNA 68 N Myc 68 p# Shc 68 neuroligins 68 basal forebrain 68 oncoproteins 68 epithelial cell 68 TGF beta 68 receptor subtype 68 GSK3B 68 beta amyloid peptide 68 endonuclease 68 induces apoptosis 68 glucocorticoid receptors 68 CENP E 68 SVZ 68 Arp2 3 68 PDE#A 68 NADPH oxidase 68 RIP1 68 Kupffer cells 68 methyl D aspartate 68 beta1 integrin 68 EAAT2 68 TIMP 1 68 lipid homeostasis 68 binding affinities 68 replicon 68 Treg cells 68 MDM2 68 aminopeptidase 68 suppressor cells 68 apoptotic cell 68 neurotrophic factors 68 intracellular accumulation 68 IRF5 68 HEK# cells 68 ErbB1 68 STAT4 68 TORC1 68 enkephalin 68 striated muscle 68 neuromelanin 68 amyloid ß 68 sRNA 68 cyclin dependent kinase inhibitor 68 palytoxin 68 lysophosphatidic acid 68 cell signaling pathways 68 Amino acid 68 synthetase 68 MyD# 68 amyloidogenic 68 HPA axis 68 uPA 68 plasmin 68 ligand receptor 68 oncogenic 68 LNCaP cells 68 fibrin deposition 68 motor neuron degeneration 68 neurosteroids 68 tumor angiogenesis 68 ryanodine receptor 68 catabolism 68 PTH secretion 68 ADAM# 68 myogenic 68 receptor inhibitor 68 adipogenesis 68 colorectal tumor 68 Vpr 68 palmitate 68 Hypoxia Inducible Factor 68 peroxisomes 68 prostaglandin D2 68 ouabain 68 striatal 68 inverse agonist 68 cellular metabolism 68 PKM2 68 transgenic mouse model 68 aT cell 68 inhibitory neurotransmitters 68 mTOR mammalian target 68 Leydig cell 68 MyoD 68 pyrimidine 68 68 FGFR2 68 aP2 68 excitatory synapses 68 astrocyte 68 anaphase promoting complex 68 neurotrophin 68 Trp p8 68 HMG CoA reductase 68 umbilical vein 68 viral proteins 68 RANK ligand 68 abnormal angiogenesis 68 guanosine 68 PDE1 68 hematopoietic cells 68 Sp1 68 adrenocortical 68 nitric oxide synthase NOS 68 enzyme phosphodiesterase 68 aberrantly activated 68 polypeptides 68 cellular senescence 68 phosphatidylinositol 68 toxic beta amyloid 68 EGFR pathway 68 neural progenitor cells 68 NPD1 68 chemokine receptors 68 chromosomal instability 68 VIPR2 68 tumor stroma 68 TTR gene 68 PP2A 68 Hh signaling 68 integrins 68 glutamate receptor 68 nicotinic acetylcholine receptor 68 collagens 68 peroxidation 68 glycogen metabolism 68 antisense inhibition 68 Hepatocytes 68 follistatin 68 hTERT 68 adenosine diphosphate ADP 68 Ca2 + 68 flavopiridol 68 polyamines 68 telomerase activity 68 interleukin IL -6 68 vacuolar 68 substrate specificity 68 tubulin 68 gene rearrangements 68 HER2 receptors 68 RNA polymerases 68 Th# 68 trans splicing 68 potent inducer 68 chitinase 68 Aβ 68 steroidogenesis 68 phosphatases 68 Cdc#