Related by context. All words. (Click for frequent words.) 69 phenotypic variation 67 paralogs 67 orthologs 67 cDNAs 66 cytochrome b 66 QTLs 66 sexually dimorphic 66 indels 65 mutant allele 65 missense mutations 65 Jhdm2a 65 genetic loci 65 Alu elements 65 mRNA transcripts 65 heterozygotes 65 epistasis 65 mtDNA mutations 65 TMPRSS2 ERG fusion 65 nucleotide substitutions 65 mitochondrial DNA mtDNA 64 imprinted genes 64 orthologous 64 #S rRNA 64 inbred strains 64 pathogenic mutations 64 fig. S4 64 A. thaliana 64 differential gene expression 64 prion gene 64 FGFs 64 coding exons 64 methylation patterns 64 H#K#me# 64 mRNA molecules 64 androgen receptor gene 63 cis regulatory 63 ploidy 63 mitochondrial gene 63 chromosomal rearrangement 63 PTPN# 63 transgene expression 63 PrPSc 63 CYP#D# gene 63 differentially expressed genes 63 chimp genomes 63 allelic 63 oncogenic transformation 63 miRNA genes 63 morphological characteristics 63 transcriptomes 63 familial pancreatic cancer 63 metabolomic profiles 63 heritable traits 63 Supplementary Table 63 splice variants 63 A. gambiae 63 histone modifications 63 #S rDNA 63 somatic mutations 63 gene deletions 63 mitochondrial proteins 63 genomic alterations 63 mitochondrial genomes 63 phylogenetic trees 63 STAT4 63 DNA methylation patterns 62 evolvability 62 sequence homology 62 phylogenetic analyzes 62 inhibin B 62 paternally inherited 62 ortholog 62 microcephalin 62 mosaicism 62 Foxp3 62 CD#c 62 introgression 62 HLA DRB1 62 ontogenetic 62 microRNA expression 62 nucleotide sequence 62 APOE genotype 62 morphogen 62 Supplementary Fig 62 K ras mutations 62 metazoan 62 Fig. 3b 62 distantly related species 62 X chromosome inactivation 62 germline mutations 62 miRNA expression 62 gene duplications 62 epigenetic modification 62 HOTAIR 62 microdeletions 62 bacterial genomes 62 phenotypic differences 62 indel 62 spontaneous mutations 62 virulence genes 62 genotype phenotype 62 bilaterians 62 cDNA libraries 62 intergenic 62 TCF#L# gene 62 ncRNA 62 viral genomes 62 chordate 62 allelic variation 62 CD# expression [001] 62 non coding RNA 62 allele frequencies 62 differentially regulated 61 phenotypically 61 #S rRNA gene 61 polygenic 61 SCN5A 61 quantitative trait loci 61 hypermethylated 61 HER2 expression 61 multivariate regression 61 protein acetylation 61 tumorigenicity 61 glycolytic 61 untranslated regions 61 laterality 61 Fig. 2a 61 granulosa cell 61 amino acid sequences 61 Fig. 1b 61 P cadherin 61 D. melanogaster 61 assortative mating 61 noncoding RNA 61 previously uncharacterized 61 polyploid 61 phenotypic traits 61 DNMT1 61 epigenetic modifications 61 HbF 61 sequenced genomes 61 genomic variation 61 Arabidopsis genes 61 Dictyostelium 61 germline cells 61 totipotent 61 chimpanzee genomes 61 microsatellite markers 61 maternally inherited 61 #S rRNA genes 61 NR#A# gene 61 Arabidopsis plants 61 X. laevis 61 single celled yeast 61 noncoding RNAs 61 familial aggregation 61 VHL gene 61 polyadenylation 61 beta1 integrin 61 cyclin E 61 ABCB1 gene 61 #BP# 61 hamartomas 61 LRP5 61 lincRNA 61 epidermal cells 61 fig. S1 61 nucleotide substitution 61 MC4R gene 60 isotypes 60 heritable variation 60 recessive trait 60 Poisson regression 60 rRNA 60 coding genes 60 segmental duplications 60 homozygosity 60 de novo mutations 60 fungal genomes 60 intergenic regions 60 phylogenetic analysis 60 phylogenetic 60 RRM1 60 eukaryotic cell 60 noncoding 60 MC1R gene 60 haplogroups 60 ligand receptor 60 metazoans 60 cellular prion protein 60 KIAA# 60 normal karyotype 60 vertebrate embryos 60 excitatory synapses 60 coexpression 60 aneuploid 60 neurite outgrowth 60 uPAR 60 clinicopathological 60 proteomes 60 splice junctions 60 subcellular compartments 60 SCN1A 60 observable traits 60 PrPC 60 stomatal 60 nucleotide sequences 60 HMGA2 60 UGT#A# * 60 mRNA encoding 60 soluble proteins 60 Fig. 1A 60 miRs 60 thermodynamic stability 60 genetic relatedness 60 anterior pituitary 60 HLA G 60 mammalian genomes 60 homologies 60 myosins 60 prion strains 60 RNA polymerases 60 phylogenetically 60 FGF signaling 60 DNA demethylation 60 posttranslational modifications 60 phylogeographic 60 aneuploid cells 60 coding sequences 60 modifier genes 60 transfected cells 60 PGCs 60 HER2 neu 60 ribosomal RNA rRNA 60 C#Y 60 CagA 60 inhibitory receptor 60 RNA sequences 60 histone modification 60 nucleosome positioning 60 transcriptional regulation 60 conserved sequences 60 autosomal 60 intracellular signal transduction 60 Fig. 1D 60 constitutively expressed 60 DARPP 60 evolutionary divergence 60 endocasts 60 mutant alleles 60 sialic acids 60 renal cysts 60 recombination hotspots 60 genetically encoded 60 Leydig cells 60 genotypic 60 Yamanaka recipe 60 telomere lengths 60 globin genes 60 archaeal 59 M. pneumoniae 59 microRNA miR 59 C. neoformans 59 microarray gene expression 59 alternatively spliced 59 proline rich 59 Mendelian 59 constitutively active 59 ribonucleic acids 59 LRAT 59 miRNA sequences 59 motor neuron degeneration 59 p# mutations 59 positional cloning 59 protein isoforms 59 C. albicans 59 Treg cell 59 nonoverlapping 59 mutated K ras 59 metalloproteinases 59 fluorescence intensity 59 Fragile X gene 59 chromosomal aberrations 59 NRF2 gene 59 chromosomal regions 59 BRAF protein 59 EGFR protein 59 HLA genes 59 RNA transcripts 59 somatic mutation 59 neuroligins 59 Entamoeba 59 Phylogenetic 59 ncRNAs 59 embryoid bodies 59 germline 59 Pearson correlation coefficients 59 valine 59 motoneurons 59 microdeletion 59 pseudogenes 59 colorectal tumor 59 HepG2 cells 59 Fig. 1a 59 Gaussian distribution 59 GBA mutations 59 CXCL5 59 BDNF gene 59 VEGFR1 59 mammary stem cells 59 cisplatin resistant 59 epigenetically 59 genetic lineages 59 bimodal distribution 59 parthenogenetic 59 hippocampal neurons 59 ERK signaling 59 inherited mutations 59 intronic 59 plastids 59 P. gingivalis 59 MC1R 59 homologues 59 linkage disequilibrium 59 homozygote 59 Chlamydomonas 59 biogenesis 59 KCNQ1 59 Drosophila genome 59 GFP fluorescence 59 monozygotic twins 59 fru 59 β galactosidase 59 miR #b [002] 59 human leukocyte antigens 59 coevolution 59 palladin 59 glycosylated 59 TRIM5 59 epigenetic silencing 59 mammalian brains 59 Dpp 59 enterotypes 59 Fas ligand 59 SLC#A# [002] 59 MLH1 59 papillomas 59 mRNA expression 59 cytosolic 59 S. cerevisiae 59 PHLPP 59 cypin 59 chromosome #p#.# 59 Immunohistochemical analysis 59 odorant receptor 59 HAR1 59 chromosomal rearrangements 59 Trichophyton rubrum 59 phylogenetic relationships 59 hemagglutinin gene 59 telomerase inhibition 59 telomeric 59 telomere DNA 59 Bacillus thuringiensis bacterium 59 p# activation 59 homologs 59 ciliated 59 olfactory receptor 59 alpha synuclein protein 59 clade B 59 PER2 59 subcellular localization 59 RUNX3 59 budding yeast 59 mammalian tissues 59 fruitflies 59 circadian clock genes 59 Confocal microscopy 59 NF1 gene 59 causal variants 59 #q# deletion 59 SNP rs# [002] 59 3'UTR 59 genetic polymorphism 59 eusociality 59 homodimer 59 amino acid substitutions 59 CHI#L# 59 NPY gene 59 clonally 59 airway responsiveness 59 chromosomal instability 59 primary cilia 59 piRNAs 59 phylogenies 59 tyrosine phosphorylation 59 cytosine methylation 59 HLA molecules 59 HBx 59 mutant proteins 59 physicochemical properties 59 prokaryote 58 Genetic variation 58 vitellogenin 58 microRNA molecules 58 proteolytic activity 58 HER2 positivity 58 metabolite concentrations 58 drug metabolizing enzymes 58 vertebrate genomes 58 BRAF V#E mutation 58 GSTM1 gene 58 glutamic acid decarboxylase 58 outcrossing 58 dizygotic twins 58 Prochlorococcus 58 #p#.# [001] 58 costimulatory 58 chloroplast genome 58 gene amplification 58 CHD5 58 cohesin 58 S#A# [002] 58 Hox genes 58 primate genomes 58 P falciparum 58 MiRNAs 58 pseudogene 58 Or#b 58 serum antibodies 58 clefting 58 multigenic 58 autosomes 58 insertions deletions 58 malaria parasite genome 58 FGFR4 58 CDK4 58 MAPK pathway 58 enolase 58 extramedullary 58 Amino acid 58 SLC#A# [001] 58 VNTR 58 familial ALS 58 SRY gene 58 genes encoding 58 subcellular 58 Hh pathway 58 K ras gene 58 morphologic 58 metabolome 58 neural progenitor 58 C. jejuni 58 Leydig cell 58 statistically significant correlations 58 molecular abnormalities 58 phylogenetic tree 58 phenotypic 58 mutational analysis 58 gene expression microarrays 58 etiologic 58 embryonic tissues 58 androgen signaling 58 ß amyloid 58 alternative splicing 58 dimorphic 58 sexual dimorphism 58 evolutionary conserved 58 MSH2 58 LPA gene 58 amyloid deposition 58 fluoroquinolone resistance 58 glutamate glutamine 58 downregulated 58 umbilical vein 58 IFN γ 58 neuroanatomical 58 deleterious mutations 58 secretory pathway 58 histone H4 58 SMAD4 58 hepatoma 58 P gp 58 dimeric 58 prion infection 58 histopathologic examination 58 interconversion 58 major histocompatibility complex 58 missense mutation 58 isoforms 58 yeast genome 58 figs. 58 previously undescribed 58 perilipin 58 radial glia 58 assortative 58 LIS1 58 ORFs 58 herpesviruses 58 DLC1 58 ovarian follicles 58 ciliates 58 FUS1 58 synuclein 58 GnRH neurons 58 PHD2 58 Pseudomonas syringae 58 T. brucei 58 heterologous expression 58 nucleolus 58 antisense RNA 58 synaptic proteins 58 multiple logistic regression 58 synovial cells 58 Fig. 1c 58 DNA rearrangements 58 #q#.# [002] 58 MHC molecules 58 T. gondii 58 replicon 58 sRNA 58 zebrafish genome 58 monozygotic 58 APOE allele 58 Immunohistochemical staining 58 cybrid 58 alpha synuclein gene 58 ribosomal proteins 58 covariate 58 taxa 58 HCV replication 58 structural rearrangements 58 HFE gene 58 vacuolar 58 Xenopus 58 trans palmitoleate 58 isogenic 58 microRNAs miRNAs 58 placental mammals 58 ERK2 58 multivariate logistic regression 58 Fig. 2A 58 morphologically 58 hematopoietic cells 58 FKBP# 58 terrestrial vertebrates 58 sCJD 58 susceptibility loci 58 Telomere length 58 eukaryote 58 DQB1 * 58 CYP#C# gene 58 amino acid residues 58 heterozygosity 58 subcellular structures 58 phenotypic expression 58 bronchial epithelial cells 58 osteosarcomas 58 transcriptional repressor 58 lung epithelium 58 hnRNP 58 EGFP 58 CNTNAP2 58 Fig. 3a 58 constitutively 58 ENPP1 58 somatostatin 58 homologous genes 58 multivariate Cox 58 SATB1 58 clinico pathological 58 glycosylation profile 58 Notch signaling pathway 58 childhood leukemias 57 phenotypic characteristics 57 polyploidy 57 chromosomal deletions 57 ZNF# 57 alveolar epithelial cells 57 breast carcinomas 57 immunodominant 57 homozygotes 57 stereochemical 57 CEACAM1 57 endonuclease 57 distinct subtypes 57 cAMP signaling 57 epigenetic reprogramming 57 sphingolipid 57 JAK STAT 57 monomorphic 57 seropositivity 57 transcriptional profiles 57 karyotypes 57 allele frequency 57 bacteria archaea 57 phospholipase 57 eotaxin 57 S. pombe 57 evolutionary relatedness 57 RTKs 57 gene polymorphisms 57 trophoblast cells 57 genetic aberrations 57 micro RNAs 57 eIF4E 57 N. gonorrhoeae 57 eukaryotic organisms 57 quasispecies 57 transmembrane domains 57 transfection efficiency 57 TTR gene 57 monophyletic 57 pleiotropic 57 conditional logistic regression 57 multicellular organism 57 mycoplasmas 57 EGFR mutations 57 lipoprotein cholesterol 57 protein tyrosine phosphatase 57 Wwox 57 RCAN1 57 genomewide 57 tubule 57 ribosomal RNA 57 HMGA1 57 CCR7 57 GBM tumors 57 TIMP 1 57 male prairie voles 57 mitochondrial mutations 57 ectopic expression 57 lactate dehydrogenase 57 MMP9 57 Arabidopsis genome 57 MECP2 gene 57 BioMAP ® 57 ABCB1 57 frameshift mutation 57 UTRs 57 polyploids 57 proteins misfold 57 carcinoembryonic antigen 57 meiotic recombination 57 nematode C. elegans 57 brucei 57 microRNA molecule 57 molecular phylogenetic 57 organismal 57 keratins 57 dyads 57 melanocyte 57 serum PTH 57 nucleus Chinnery 57 X inactivation 57 miRNA molecules 57 picomolar 57 substrate specificity 57 mammaglobin 57 tryptase 57 cathepsin B 57 cyclin B1 57 dynamin 57 SLITRK1 57 gene locus 57 amphioxus 57 MALAT1 57 CHD7 57 phylogeny 57 ERBB2 57 E#F# 57 fission yeast 57 pea aphid 57 scintigraphic 57 sarcosine 57 chloroplast 57 Wnt proteins 57 prostate carcinoma 57 segmental duplication 57 insulin signaling pathways 57 Phylogenetic analysis 57 TNFR1 57 lymphovascular invasion 57 TOP2A gene 57 hybridizations 57 multiplicative 57 ORMDL3 57 p# alpha [002] 57 multivariable analysis 57 Prevotella 57 deacetylation 57 gp# protein [002] 57 binding affinities 57 Trypanosoma brucei 57 ALK mutations 57 astrocytic 57 invariant 57 microarray experiments 57 neoplastic 57 KCNH2 57 TGF ß 57 follicular fluid 57 Xenopus laevis 57 clades 57 dose proportionality 57 site directed mutagenesis 57 operons 57 noncoding DNA 57 COL#A# 57 dopamine neuron 57 Candida species 57 fruitfly Drosophila 57 Stat1 57 hammerhead ribozyme 57 phenotypic variability 57 miR #a [002] 57 amyloidogenic 57 globular proteins 57 polyamine 57 miRNAs miR 57 lymphoid cells 57 genomic imprinting 57 gene expression patterns 57 Hsp# [001] 57 retinal neurons 57 chromatin modification 57 tumor suppressors cytokines 57 condensin 57 NR#A# 57 nucleated cells 57 cDNA library 57 Fig. 2B 57 HSPCs 57 glial tumors 57 apoptosis pathway 57 HERV 57 titin 57 striated muscle 57 subfamilies 57 Ab# 57 Eg5 57 Multivariate analysis 57 prion protein gene 57 mitochondrial genome 57 X4 viruses 57 EF Tu 57 morphologically distinct 57 nucleolar dominance 57 bivariate 57 uncharacterized 57 meadow vole 57 noninfected 57 MMP# 57 GSTP1 57 immunoreactivity 57 Neuregulin 1 57 KRAS oncogene 57 colocalization 57 hypervariable 57 vivax 57 beta subunit 57 mitochondrial DNA mutations 57 transcriptome sequencing 57 MT1 MMP 57 fluorescently tagged 57 tetramers 57 ± SEM 57 antigenic epitopes 57 breast cancer subtypes 57 IGFBP2 57 osteoblast 57 hierarchical clustering 57 TMEM#B 57 multivariate analyzes 57 reproductively isolated 57 insulin signaling pathway 57 IDH1 mutation 57 operon 57 coactivators 57 SGK1 57 metaplasia 57 transcriptomics 57 FDG uptake 57 CAG repeats 57 CC genotype 57 Macaca mulatta 57 Genotypic 57 chromosome #q# [001] 57 Pollen grains 57 LKB1 57 inhomogeneities 57 FGF2 57 serum homocysteine 57 bdelloid rotifer 57 peroxisome 57 functional polymorphism 57 genetic variants associated 57 #ß 57 pituitary hormone 57 carboxyl terminal 57 selfing 57 TP# gene 57 chromosome #q 57 cyclophilin D 57 transposable elements 57 observable characteristics 57 cell nuclei 57 EMBL scientists 57 lognormal 57 genetic heterogeneity 57 M. bovis 57 evolutionarily conserved 57 caveolae 57 epigenetic changes 57 RFLP 57 female genital tract 57 nanomolar 57 KLF# 57 microstructural 57 CXCL# 57 prokaryotic 57 CCR5 delta# 57 Rap1 57 multivariable Cox 57 hemoglobins 57 somites 57 V#F mutation 57 cytopathic 57 proteins encoded 57 dependences 57 CYP#A# gene 57 pancreatic endocrine 57 midgut 57 trophoblasts 57 transferrin receptor 57 progranulin gene 57 chromosomal anomalies 57 isotype 57 MYH9 57 desmosomes 57 estrogen receptor alpha 56 chromatin structure 56 plasma leptin 56 Wolbachia 56 mtDNA sequences 56 NS5B 56 HLA gene 56 plant Arabidopsis thaliana 56 Y chromosomal 56 evolutionary lineages 56 Rickettsia 56 sporadic ALS 56 MAPKs 56 cortical neurons 56 TIMP 56 cysteines 56 doublesex 56 BDNF protein 56 carotid artery thickness 56 familial clustering 56 cyclic AMP cAMP 56 olfactory receptors 56 vitamin D receptor 56 vitamin D receptors 56 β1 56 unmethylated 56 immunoregulatory 56 Univariate analysis 56 hypothalamic pituitary 56 rs# [002] 56 nematode Caenorhabditis elegans 56 autophagic 56 intact parathyroid hormone 56 morphometric 56 mucinous 56 EBNA1 56 cell adhesion molecule 56 mutational 56 Eukaryotes 56 logistic regression analysis 56 protein conformation 56 NNRTI resistance 56 #S ribosomal RNA 56 mammary cells 56 neutralizing antibody responses 56 Leishmania parasites 56 histological examination 56 worm C. elegans 56 mean ± SEM 56 teleost fish 56 var genes 56 Kaplan Meier survival 56 cellularity 56 Cathepsin B 56 replicase 56 leptin receptor 56 L. pneumophila 56 carcinoids 56 Pax6 56 synthases 56 H#K# [001] 56 TOP2A 56 hyperplastic 56 fully sequenced genomes 56 non mammalian vertebrates 56 nAChR 56 Hair follicles 56 EGF receptors 56 monogenic 56 KLF4 56 transmembrane 56 prodynorphin 56 H#Y 56 Cyclin E 56 Proteobacteria 56 nucleolin 56 metalloprotease 56 inferential statistics 56 isoenzymes 56 SHANK3 56 NFKBIA 56 bisulfite sequencing 56 CCL#L# 56 postnatal foreskin fibroblasts 56 dimorphism 56 TT genotype 56 gastric carcinomas 56 antibody antigen 56 annelid worms 56 TMPRSS2 ERG 56 apo E 56 glomerular 56 proteolysis 56 statistical correlations 56 genomic deletions 56 2D 4D ratio 56 histologic subtypes 56 seminomas 56 prokaryotes 56 short hairpin RNAs 56 comparative genomic 56 AMACR 56 Genetic mutations 56 miR# 56 differentially expressed 56 Mus musculus 56 ATPase activity 56 Alternative splicing 56 loci 56 AVPR1A 56 spontaneous mutation 56 artiodactyls 56 brassinosteroid 56 serine threonine kinase 56 directed mutagenesis 56 spectrophotometric 56 ChIP chip 56 oviposition 56 mammalian fatty acid 56 Sonic hedgehog 56 hexose 56 ChIP Seq 56 p#/CBP 56 CD# expression [002] 56 steroidogenic 56 inactive X chromosome 56 thioredoxin 56 KRAS mutations 56 protein ligand 56 nitrotyrosine 56 histological subtype 56 phosphorylated tau 56 mutant enzymes 56 genes encode proteins 56 antisense inhibition 56 homology 56 transposon 56 hyperactivation 56 microarray datasets 56 ubiquitin ligases 56 morphogens 56 chemotactic 56 transgenic mice expressing 56 abnormal chromosomes 56 immunohistochemical analysis 56 intercellular signaling 56 MEF2A 56 primordial germ cells 56 hydrated electron 56 PON1 gene 56 apoE 56 morphological similarities 56 Fig. 1B 56 multicellularity 56 p# MAPK 56 miR #a [001] 56 pCR 56 cortisol hormone produced 56 colugos