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(Click for frequent words.) 63 physicochemical properties 60 physico chemical properties 58 pleiotropic effects 56 Anticalins R 56 enzyme kinetics 56 substrate specificity 56 Anticalins ® 55 molecular biomarkers 55 endogenous ligands 55 pore sizes 55 peptide conjugated 55 intracellular signal transduction 55 monodisperse 55 putative biomarkers 55 N glycan 55 glycosylated 55 splice variants 54 IntroductionThe 54 Aromatase 54 metabolomic profiles 54 nanogels 54 extracellular proteins 54 enzyme rHuPH# 54 biotransformation 54 A2A adenosine receptor 54 Anticalins 54 endophenotypes 54 kinase inhibition 54 nanocrystalline materials 54 pharmacodynamic parameters 53 moieties 53 plasma lipid 53 norepinephrine reuptake inhibition 53 bicyclic 53 immunomodulation 53 C3 convertase 53 druggable 53 stereochemical 53 DiLA2 53 cytoskeletal structure 53 synthetic peptides 53 sequence homology 53 macrocycles 53 polymersomes 53 proteins peptides 53 chromatin structure 53 axon guidance 53 secretory pathway 53 vitamin D analogs 53 vivo potency 53 protein tyrosine phosphatases 53 chemical reactivity 53 cytotoxicity assays 53 homodimers 53 MEK1 53 multiplexed assays 52 multigenic 52 biosynthetic pathway 52 peptide inhibitors 52 epithelial tissues 52 liquid crystalline 52 gp# protein [002] 52 biominerals 52 VDAs 52 rxRNA 52 MT1 MMP 52 transitivity 52 photosystem II 52 effector function 52 NR2B subunit 52 immunoregulatory 52 CD1d 52 hexose 52 ubiquinol 52 rheological properties 52 particle morphology 52 stranded nucleic acids 52 ELISAs 52 metabolizing enzymes 52 viscoelastic properties 52 DNA gyrase 52 FSH receptor 52 proline rich 52 histone code 52 inferential statistics 52 heterodimers 52 variograms 52 combinatorial libraries 52 osteoconductive 52 mechanistic insights 52 UsiRNAs 52 binding affinities 52 RNAi compounds 52 agonist antagonist 51 γ secretase 51 coexpression 51 multiplex assay 51 nucleic acid molecules 51 osteoinductive 51 thymidylate synthase TS 51 molecular determinants 51 modifier genes 51 beta subunit 51 protein tyrosine phosphatase 51 surface functionalization 51 posttranslational modification 51 phage display technology 51 5 hmC 51 pathogenic mechanisms 51 differential gene expression 51 prognostic indicators 51 ligand receptor 51 pleiotropy 51 microwell plate 51 molecules peptides 51 linear pharmacokinetics 51 phenotypic expression 51 proteolytic activity 51 pathophysiological mechanisms 51 Membrane proteins 51 morphogen 51 catalytic antibodies 51 substitutability 51 affinity ligands 51 Adnectin 51 SIRT1 activation 51 adaptogens 51 diffusion coefficients 51 diffusible 51 granzyme B 51 p# alpha [002] 51 peptides proteins 51 DNA methylation patterns 51 mammalian circadian clock 51 anti angiogenic drugs 51 APOE genotype 51 opioid antagonists 51 phenotypic variation 51 Fibroblast growth 51 organoleptic properties 51 serum PTH 51 integrin receptor 51 ENMD # 51 glycosylation profile 51 Computational biology 51 breast cancer subtypes 51 antiangiogenic agents 51 monomeric 51 glycosylation pattern 51 sphingomyelin 51 Nanobodies 50 serum biomarkers 50 ionic currents 50 molecular abnormalities 50 intracellular membranes 50 therapeutically relevant 50 LNA TM 50 situ gelling 50 ligand binding 50 endpoint assays 50 trans splicing 50 sd rxRNA 50 fluorogenic 50 enzyme catalysis 50 microtissues 50 phosphorylated proteins 50 rxRNA compounds 50 additively 50 PDZ domain 50 hERG 50 pleiotropic 50 cell adhesion molecules 50 clinically validated targets 50 tyrosine phosphorylation 50 etiologic 50 soluble CD# 50 Reproducibility 50 DNA demethylation 50 optical biosensors 50 biophysical properties 50 prognostic biomarker 50 intercellular signaling 50 discriminant 50 prognostic markers 50 patterning technique 50 posttranslational modifications 50 tetrapod quantum dots 50 endonucleases 50 vitamin D receptors 50 Flow cytometry 50 ERK signaling 50 nicotinic receptor 50 antiproliferative effects 50 Angiotensin converting enzyme 50 liposome formulation 50 Repeatability 50 alloying elements 50 multigene 50 biocompatible nanoparticles 50 sirtuin enzymes 50 reproducible measurements 50 ADAMTS# 50 PPARg 50 homochirality 50 thyrotropin 50 neurobiological mechanisms 50 perturbation theory 50 multiphoton microscopy 50 metabolomic profiling 50 bFGF 50 ADME properties 50 aggrecan 50 deletion mutant 50 potency selectivity 50 interindividual variability 50 elastic modulus 50 GFP fluorescence 50 fatty acid biosynthesis 50 monoclonals 50 microenvironments 50 macromolecular complexes 50 MTT assay 50 nanotubes nanowires 50 costimulation 50 selective inhibition 50 viscoelasticity 50 FGFs 50 physiologically relevant 50 U1 Adaptors 50 transcriptional regulation 50 seminomas 50 complexation 50 Endothelial dysfunction 50 nanoscale phenomena 50 pharmacodynamic properties 50 macromolecular 50 5 hydroxymethylcytosine 50 pharmacodynamic markers 50 biologically inert 50 Bionate ® PCU 50 chromosomal rearrangement 50 fusion enhancers 50 follicular dendritic cells 50 gamete formation 50 heritable variation 50 cystatin 50 siRNAs targeting 50 microstructural 50 SITC code 50 pharmaceutically relevant 50 proteoglycan 49 Experimentally 49 serum lipid 49 clade B 49 macromolecule 49 lognormal 49 maturation inhibitors 49 chemotypes 49 biological macromolecules 49 antitumor efficacy 49 oxidases 49 pegylated IFN 49 P2X 49 antitumor effect 49 heterotrophic 49 nucleated cells 49 sGC 49 delipidation 49 antibody antigen 49 phage display libraries 49 chemosensitivity 49 hydrophobicity 49 elemental composition 49 microRNA profiling 49 Heterogeneity 49 SGLT 2 49 immunogens 49 tribological 49 bioconjugation 49 CB2 receptor 49 threshold voltages 49 biologically inactive 49 biologic therapeutics 49 Cdc7 49 neuropsychological impairment 49 vascular endothelial 49 unimodal 49 Laminin 49 peripheral insulin sensitivity 49 Methotrexate MTX 49 transcriptional machinery 49 osteogenic 49 pituitary adenomas 49 developmental neurotoxicity 49 multidomain 49 KLF4 49 stereochemistry 49 neural substrates 49 tumorigenicity 49 glycosaminoglycans 49 wafer uniformity 49 rxRNA TM compounds 49 patient subpopulations 49 PET tracers 49 nanocarriers 49 engineered anticoagulant 49 unnatural amino acids 49 dimeric 49 enzymatic digestion 49 intracellular signaling 49 Eg5 49 coactivators 49 bioactives 49 #T# L1 cells 49 adsorbate 49 therapeutic equivalence 49 #T# L1 49 neuroanatomical 49 DLC1 49 conductivities 49 circuitries 49 striated muscle 49 ImmuneY2 49 oligosaccharide 49 Signal transduction 49 ACCU BREAK 49 excision repair 49 proliferative disorders 49 VEGF inhibitors 49 proton MR spectroscopy 49 GLUT4 49 dependences 49 Dystrophin 49 physiologic mechanisms 49 lipopeptides 49 differentiable 49 nutrigenomic 49 IgG1 antibodies 49 MMP# 49 ERK phosphorylation 49 androgen deficiency 49 GS2 M 49 methylated DNA 49 recombinant plasma 49 pharmacological approaches 49 PIP3 49 carcinoids 49 IgG1 49 nAChRs 49 transmembrane protein 49 isotype 48 Metallophile ™ Technology 48 receptor ligands 48 distinct subtypes 48 stimulate insulin secretion 48 post translational modifications 48 transcriptional repressor 48 BiTE 48 PI3K/mTOR 48 biocompatible polymers 48 Soil pH 48 potentiating 48 genetic susceptibilities 48 RRM1 48 HDL particle 48 TGF Beta 48 axonal degeneration 48 ZFPs 48 silico prediction 48 PDEs 48 Calcium phosphate 48 PDE1 48 neuropsychiatric diseases 48 HIF 1a 48 Selectivity 48 5 HT2A serotonin 48 VEGF expression 48 polymer scaffold 48 protein filaments 48 transgene expression 48 electrophysiological properties 48 spectroscopic methods 48 CYP#A# enzyme 48 evolvability 48 predictive biomarkers 48 intestinal epithelium 48 proteolytic 48 metabonomics 48 Reynolds Risk Score 48 neuroactive 48 tetramer 48 powder diffraction 48 glycosyltransferase 48 mechanistic studies 48 multipotent 48 eTag assays 48 Fibroblast 48 microRNA molecule 48 Eukaryotes 48 Annexin V 48 proapoptotic 48 magnetosomes 48 pro angiogenic 48 rheological 48 p# activation 48 underlying molecular mechanisms 48 xenobiotic 48 boron nitride 48 optimal dosing 48 DNA glycosylase 48 iPS derived 48 multiplex immunoassays 48 QRS width 48 extracellular domains 48 ribonucleoprotein 48 pharmacodynamic endpoints 48 peptide fragments 48 fermentable 48 osteoblast 48 patented Bioral 48 intracellular uptake 48 Rap1 48 proteolysis 48 Upregulation 48 ATIR ™ 48 MTHFR gene 48 vascular disrupting agents 48 F actin 48 bone metabolism 48 HMG CoA reductase 48 aluminosilicate clay 48 soy protein concentrates 48 Sgk1 48 neuromuscular junction 48 PICM #H 48 chelating agents 48 immunoglobulin G 48 MALDI-TOF/TOF 48 UCOE 48 prognostically 48 myosins 48 telomere maintenance 48 kinesin motor 48 metabolic enzymes 48 acyclic 48 phenotypic variability 48 resonant frequencies 48 aT cell 48 osmolality 48 secretase 48 co receptor tropism 48 MTP inhibitor 48 costimulatory 48 pharmacologic intervention 48 multiplex PCR 48 titin 48 DFT calculations 48 intrinsic viscosity 48 cis regulatory 48 ontogenetic 48 Umbilical cord stem cells 48 nanostructuring 48 radionuclide therapy 48 biochemical mechanisms 48 desmosomes 48 underlying pathophysiology 48 fission yeast 48 keratinocyte 48 nano fluidic 48 mass spectrometric 48 ChIP chip 48 P cadherin 48 dimensional nanostructures 48 Bloom taxonomy 48 osteoblastic 48 Alternative splicing 48 biodegradable biocompatible 48 reaction kinetics 48 biomedically 48 recombinant albumin 48 LSI #P 48 molecular subtypes 48 hydrodynamic radius 48 extracellular matrices 48 therapeutically beneficial 48 cognitive affective 48 biochemical abnormalities 48 Th2 responses 48 selectivities 48 neurotrophic 48 cathepsins 48 targeting PCSK9 48 histone modifications 48 heterogeneously 48 mitochondrial enzyme 48 Alfacell proprietary ribonuclease 48 phenotypic traits 48 pharmacologic agents 48 non coding RNA 48 supramolecular structures 48 PPARγ 48 serum antibodies 48 tumor hypoxia 48 Cardiorespiratory fitness 48 intracellular compartments 48 phosphoinositide 48 eigenvalues 48 PAMs 48 apolipoproteins 48 Fc receptor 48 demyelinating diseases 48 apoE 48 nonlinearities 48 analyte 48 Ge substrates 47 LDL HDL 47 antigen receptors 47 cleavable 47 ELISA assays 47 logistic regressions 47 serum concentrations 47 clonally 47 peroxisomal 47 KDOQI 47 thiopurine 47 proteins nucleic acids 47 AEC Q# specifications 47 spectrophotometric 47 c MET 47 subcellular localization 47 adjuvant systemic 47 inactivating mutations 47 glycogen synthesis 47 PARP inhibition 47 GABAB receptors 47 pharmacogenetic testing 47 Glycemic load 47 double helix molecular 47 periprocedural MI 47 methodological approaches 47 alpha7 NNR 47 small molecule tyrosine 47 Kv#.# 47 flowability 47 adipokines 47 miRNA biomarkers 47 pharmacokinetic characteristics 47 nucleotide sequences 47 stoichiometry 47 recombinant antibodies 47 Wnts 47 AdvancedMC module 47 HDACs 47 Ii Key 47 cytoprotective 47 hematopoietic cells 47 Phenotypic 47 normal physiologic 47 microcompartments 47 CHD5 47 sensory modalities 47 indicator kriging 47 HIF PH 47 Non inferiority 47 LDL receptor 47 SWNT 47 Mathematical modeling 47 osteoclast formation 47 ß1 47 noncognitive 47 ORFs 47 heritable traits 47 IL #p# 47 stem cell pluripotency 47 humoral responses 47 rRNA 47 peptidomimetic 47 neuroinflammation 47 membrane proximal 47 JAK inhibitors 47 tRNA synthetases 47 morphogens 47 c myc gene 47 monosaccharide 47 subcellular 47 osteocalcin protein 47 SOCS2 47 pharmacokinetic equivalence 47 epigenetically 47 cellular prion protein 47 IR spectra 47 mediated inhibition 47 chromatin proteins 47 subcellular compartments 47 HER2 expression 47 anti CD3 47 Tocomin ® 47 genotoxicity 47 XTEN 47 stochastic simulation 47 mesenchymal cell 47 PHD2 47 causative genes 47 photoconversion 47 Multiple logistic regression 47 TLE3 47 disaggregates 47 patentable invention 47 translationally 47 transgenic mice expressing 47 protein biosynthesis 47 antiapoptotic 47 glycosaminoglycans GAGs 47 ligand induced 47 heparanase 47 chloride channels 47 folate receptor 47 subgingival 47 Pitavastatin 47 TLR signaling 47 deeply ingrained maladaptive 47 plasma pharmacokinetics 47 inflammatory biomarkers 47 miRNA expression 47 graphene electrons 47 saccharide 47 coagulation cascade 47 cyclase 47 biomolecular interactions 47 quantitative PCR qPCR 47 peroxidation 47 transcriptional activation 47 effector functions 47 FKBP# 47 chronicity 47 HSPCs 47 HLA DQ2 47 oscillatory behavior 47 ERK1 47 adipogenic 47 eumelanin 47 Interferon beta 47 siRNA mediated 47 Ayurvedic herbs 47 histological subtype 47 piRNAs 47 NPM1 mutation 47 vitro dissolution 47 androgen signaling 47 stochastic optimization 47 CRAC channel 47 transfection reagent 47 osteoblast differentiation 47 CEACAM1 47 clinicopathological 47 inhomogeneity 47 lymphangiogenesis 47 ACh 47 adipocyte differentiation 47 cDNA libraries 47 transferrin receptor 47 phenotypic differences 47 endogenous hormones 47 Fig. 3a 47 Proteostasis Network 47 intercellular communication 47 magnetic resonance spectroscopy MRS 47 metabolize cholesterol 47 neoplastic transformation 47 prion strains 47 kimberlite phases 47 lesional 47 invention relates 47 Leydig cell 47 preservice teachers 47 immunohistochemical 47 activin 47 methylation patterns 47 MMP9 47 mitochondrial membranes 47 cypin 47 RAR beta 47 collagen degradation 47 enzymes catalyze 47 monoclonal antibodies mAbs 47 JAK STAT 47 constitutively expressed 47 solvation 47 KRAS mutation 47 osteocytes 47 AST ALT 47 bisulfite sequencing 47 superparamagnetic 47 compensatory mechanisms 47 Hsp# inhibition 47 Butyrate 47 N glycans 47 nucleolar 47 osteoid 47 evaluative criteria 47 allosteric 46 histone deacetylase HDAC 46 cellular pathways 46 PTH secretion 46 single celled yeast 46 ESBA# 46 observable characteristics 46 genomically 46 K DOQI 46 neuroligins 46 differentially expressed genes 46 homologies 46 Arabidopsis genes 46 genetic aberrations 46 C# fullerene 46 intact parathyroid hormone 46 CD#c 46 hydroxy vitamin D 46 hESC derived cells 46 colorectal carcinogenesis 46 GelSite ® 46 biostatistical analysis 46 homodimer 46 epistatic 46 vitamins minerals proteins 46 circadian genes 46 lung surfactant 46 FD SOI 46 assortative 46 Alu elements 46 quantum correlations 46 biopreservation media 46 TRPV4 46 gene amplification 46 immunological responses 46 lung epithelium 46 immunostaining 46 protein microarrays 46 oncoproteins 46 paralogs 46 H#K#me# 46 mammalian sperm 46 friability 46 uPAR 46 NS4B 46 PKC alpha 46 hypericin 46 analgesic efficacy 46 PI3K AKT 46 JAK#/JAK# 46 lentiviral vectors 46 hormone receptor status 46 emotional dysregulation 46 dosimetric 46 Microtubule 46 bifidobacterium 46 spatial temporal 46 Gene Ontology GO 46 functional annotation 46 Palatinose 46 pathophysiological 46 glucose homeostasis 46 NF KB 46 spectroscopic technique 46 XCel 4e 46 FGFR2 46 metabolomic 46 non pharmacological interventions 46 preferentially bind 46 kinase assay 46 Strong interpersonal skills 46 multiplicative 46 metabolite concentrations 46 HCV replication 46 CTLs 46 prostatic tissue 46 Gaussian distribution 46 fungal genomes 46 predictive validity 46 COL#A# 46 glomerular 46 CaM kinase II 46 virulence genes 46 RGD peptide 46 comorbid disorders 46 Sanger sequencing 46 plasma proteome 46 mAbs 46 aberrantly activated 46 QSAR 46 multifunctionality 46 TMEM#B 46 sensuous intuition 46 renal cortical 46 Toric IOL 46 G6PD deficiency 46 adjuvant AS# 46 gene expression microarrays 46 biologic pathways 46 nonpharmacologic 46 botanically derived 46 hematological parameters 46 Stromal 46 prodynorphin 46 gene polymorphisms 46 nitrotyrosine 46 RNAi therapeutic targeting 46 psychometric properties 46 evolutionarily conserved 46 mycobacterial 46 BubR1 46 metabolic dysfunction 46 inhibit viral replication 46 photostability 46 mammalian brains 46 neuronal signaling 46 Definitions vary 46 NOD mouse 46 electrode arrays 46 Homeopathic medicines 46 Schrodinger equation 46 prognostic variables 46 covalently bound 46 protein isoforms 46 experimentally validated 46 NAADP 46 macronutrient 46 lysophosphatidic acid LPA 46 gDNA 46 erection hardness 46 biosynthetic 46 synthetically derived 46 genotyping gene expression 46 astatine 46 biased ligands 46 impedance measurements 46 extracellular matrix ECM 46 LSD1 46 myofibroblast 46 magnetic anisotropy 46 multivariate regression 46 tumor histology 46 CEP# 46 myosin VI 46 genomic alterations 46 chaperone proteins 46 Integrins 46 NF kappaB activation 46 empiric therapy 46 Sertoli cell 46 transduce 46 Mass Spectrometry MS 46 physiological mechanisms 46 EF Tu 46 esophagogastric 46 cyclin E 46 transfect 46 ROC curves 46 dermal papilla 46 Anticalin ® 46 intracellular signaling pathways 46 neurofibrillary 46 SSc 46 Descriptive statistics 46 surrogate markers 46 aminotransferase 46 cognitive faculties 46 human pluripotent stem 46 cytologic 46 ZFP TF 46 recombinant antibody 46 neurexins 46 perfusion abnormalities 46 etiologic factors 46 trimeric 46 Neuroticism 46 genetic determinants 46 Zysolin TM 46 Heritability 46 homologous genes 46 alphabetic characters 46 PI3K signaling 46 Mesenchymal stem cells 46 hydrated electron 46 Genetic variation 46 C#T [002] 46 buccal absorption 46 modulatory 46 p# mutations 46 clonal expansion 46 homeobox gene 46 Liver biopsy 46 LDL particle 46 occludin 46 discriminant validity 46 GlcNAc 46 genomic variation 46 amyloid fibers 46 Pharmacokinetic studies 46 FGFR3 46 neuronal progenitor cells 46 regression equations 46 antibody cytokine 46 Skeletal muscle 46 metalloproteases 46 allele frequencies 46 lymphoid cells 46 esophageal squamous cell carcinoma 46 polyamine 46 medial frontal cortex 46 lysosomal 46 hepatic stellate cells 46 echocardiographic parameters 46 observable behaviors 46 abzymes 46 dense aerosol 46 hypercoagulable 46 SAXS 46 dose proportionality 46 extracellular signals 46 Glucocorticoids 46 tissue ingrowth 46 Bayesian statistical 46 parameter estimation 46 amphiphilic 46 interindividual differences 46 viral tropism 46 heterogeneities 46 BCR ABL mutations 46 lipid rafts 46 agarose gel electrophoresis 46 conceptual frameworks 46 etiologic agent 46 histone acetyltransferase 46 Nernst 46 nonequilibrium 46 Oral NKTR 46 RTP# 46 FoxO1 45 Genetic variations 45 calpain 45 Resveratrol supplements 45 viral etiology 45 atomically precise manufacturing 45 untranslated regions 45 NMES 45 lipid biosynthesis 45 nosology 45 aetiology 45 interconversion 45 Arp2 3 45 CD# expression [002] 45 Akt activation 45 somatoform disorders 45 S6K 45 automated immunoassay 45 beta islets 45 detection reagents 45 hepatic fibrosis 45 Kinesia 45 inhibiting viral replication 45 sensory modality 45 collagenous 45 Immunohistochemistry IHC 45 calcium phosphorous 45 III nitride 45 neurite outgrowth 45 hitherto unrecognized 45 antiplatelet therapies 45 phosphatases 45 demethylase 45 bistability 45 conserved sequences 45 differentially expressed proteins 45 cardioprotection 45 Telomere length 45 genomic biomarker 45 haematopoietic 45 causal pathways 45 electrophysiologic 45 RAS RAF MEK 45 physico chemical 45 MDx tests 45 soluble proteins 45 organoleptic 45 normal prion protein 45 histone H4 45 invariants 45 epithelial barrier 45 Vangl2 45 pressor response 45 Protein kinase 45 Specificity 45 Catenin 45 soluble solids 45 miR #a [001] 45 viral kinetics 45 noncoding RNA 45 amplicons