pleiotropy

Related by string. * * antagonistic pleiotropy *

Related by context. All words. (Click for frequent words.) 66 inferential statistics 66 evolvability 65 prodynorphin 65 DNA demethylation 65 DNA methylation patterns 65 protein conformation 65 p# activation 65 underlying molecular mechanisms 65 pleiotropic 64 conserved sequences 64 γ secretase 64 underlying pathophysiology 64 siRNA knockdown 64 physico chemical properties 64 clonal expansion 64 neuroanatomical 64 stereochemical 64 coexpression 64 posttranslational modifications 64 epistasis 64 genetic loci 64 neural substrates 64 phenotypic expression 63 intracellular signal transduction 63 pleiotropic effects 63 protein tyrosine phosphatases 63 phenotypic plasticity 63 Apobec3 63 missense mutations 63 mammalian circadian clock 63 Alternative splicing 63 colorectal carcinogenesis 63 differential gene expression 63 histone methylation 63 epigenetic mechanisms 63 allelic variation 63 intracellular signaling 63 epistatic 63 phenotypic variation 63 amyloid cascade 63 recombination hotspots 63 axon guidance 63 meiotic recombination 63 endophenotypes 63 GABAB receptors 63 transcriptional regulation 63 FKBP# 63 homologies 63 pathophysiological 62 Jhdm2a 62 HBx 62 DLC1 62 sequence homology 62 Smad3 62 neurite outgrowth 62 ADAMTS# 62 fungal genomes 62 paralogs 62 RAS RAF MEK 62 linear pharmacokinetics 62 FGFs 62 metazoan 62 androgen signaling 62 transgene expression 62 Endocannabinoids 62 operons 62 epigenetic modification 62 particle morphology 62 bacterial virulence 62 CPEB 62 Eg5 62 neurobiological mechanisms 62 MAPK pathway 62 sociological theories 62 antitumour 62 drug metabolizing enzymes 62 pathophysiological mechanisms 62 HPA axis 62 histone modifications 62 tyrosine phosphorylation 62 Pol IV 62 Sgk1 62 psychobiological 62 p# MAPK 62 oligomeric 62 adult neurogenesis 62 glycosylated 62 nanoelectronics photonics 62 JNK1 62 TGF beta signaling 62 constitutively active 62 cis regulatory 62 intercellular signaling 62 construal 61 siRNA mediated 61 mechanistically 61 morphogen 61 beta1 integrin 61 FoxO1 61 non coding RNA 61 epigenetic modifications 61 HSF1 61 protein tyrosine phosphatase 61 binding affinities 61 Fc receptor 61 haematopoietic 61 Skeletal muscle 61 c Myb 61 cypin 61 epigenetic alterations 61 heritable trait 61 eigenvalue 61 MT1 MMP 61 nucleosome positioning 61 podocyte 61 immunomodulation 61 transcriptional repressor 61 peroxisome 61 CD1d 61 enterotypes 61 mathematical formalism 61 antiapoptotic 61 microRNA expression 61 SGK1 61 neurobiological basis 61 ncRNAs 61 virulence genes 61 tiny roundworm 61 Cyclin E 61 epigenetic regulation 61 SIRT1 activation 61 microsaccades 61 circadian clock genes 61 oncogenesis 61 ACh 61 CEACAM1 61 interleukin 1beta 61 trans splicing 61 apoE 61 cAMP signaling 61 noncoding RNA 61 bioinformatic approaches 61 HCV replication 61 methylation patterns 61 P cadherin 61 beta globin gene 61 miRNA expression 61 mammalian brains 61 synaptic function 61 neuroimaging studies 61 transgenic mice expressing 61 #beta HSD 1 60 N glycan 60 observable traits 60 prefrontal regions 60 unmeasured factors 60 extracellular proteins 60 lung epithelium 60 FGF2 60 post translational modifications 60 phospholipid membranes 60 Genetic variation 60 infantile amnesia 60 neuronal dysfunction 60 breast cancer subtypes 60 histone acetylation 60 previously uncharacterized 60 histone code 60 SH2 B 60 PB1 F2 60 CRISPR Cas 60 CPT1c 60 neuronal differentiation 60 epigenetically 60 computational algorithms 60 glycolytic 60 quantum phenomena 60 LIS1 60 chromatin structure 60 morphometrics 60 clade B 60 M1 muscarinic 60 selenoproteins 60 oncogene addiction 60 chromosomal rearrangement 60 immunological responses 60 Thyroid hormones 60 APOE genotype 60 polyploidy 60 JAK STAT 60 selective inhibition 60 genes encode proteins 60 posttranslational modification 60 putative biomarkers 60 mitochondrial metabolism 60 glycolipids 60 modifier genes 60 subcellular localization 60 IRS1 60 polyploid 60 ipRGCs 60 M. pneumoniae 60 serum biomarkers 60 leptin signaling 60 biochemical abnormalities 60 viral genomes 60 TGF ß 60 LRP5 60 gene duplications 60 alpha7 NNR 60 mechanistic explanation 60 bistability 60 phylogenetically 60 steroidogenic 60 proteolytic 60 prostate carcinogenesis 60 Alu elements 60 splice variants 60 enzymatic pathways 60 activin 60 cellular pathways 60 CYP#C# gene 60 Clusterin 60 alpha syn 60 Notch signaling 60 subcellular compartments 60 neurophysiologic 60 DNMT1 60 SLC#A# [002] 60 homochirality 60 gamma oscillations 60 genome rearrangements 60 convergent validity 60 oncogenic transformation 60 fibrotic disease 60 Prof. Krainer 60 heritable variation 60 H#K#me# 60 Nedd4 60 biologic pathways 60 amyloid peptide 60 histocompatibility 60 evolutionary computation 59 metacognitive 59 striated muscle 59 vertebrate embryos 59 small molecule activators 59 enzymes catalyze 59 quasispecies 59 neurobiological underpinnings 59 uncharacterized genes 59 gut microbiota 59 KIAA# 59 ligand receptor 59 proteolysis 59 genetic polymorphism 59 Mathematical modeling 59 body louse genome 59 cognitive affective 59 prion strains 59 Nampt 59 ENPP1 59 Nod1 59 neuropsychiatric diseases 59 pyrimidines 59 serine threonine kinase 59 multigenic 59 microRNA molecules 59 c MYC 59 abzymes 59 monoamine neurotransmitters 59 transgenic mouse models 59 evolutionary conserved 59 physicochemical 59 ortholog 59 autoregulation 59 clinicopathological 59 IL #p# 59 etiologic 59 PON1 gene 59 micro RNAs 59 adipose cells 59 mitochondrial enzyme 59 synuclein 59 microstructural 59 metabolomic profiles 59 TXNIP 59 PHD2 59 myelofibrosis polycythemia vera 59 monogenic 59 glycosylation profile 59 hippocampal function 59 oxidative phosphorylation 59 DEAR1 59 telomere dysfunction 59 TGFß 59 IGFBP2 59 TRIM5 59 transcriptional activation 59 Androgen receptor 59 nongenetic 59 de novo mutations 59 Hsp# [001] 59 epiphenomenon 59 humoral immunity 59 magnetosomes 59 cellular prion protein 59 glial tumors 59 constitutively expressed 59 sphingolipid 59 polynucleotides 59 visuomotor 59 protein ligand interactions 59 PPARγ 59 microRNA molecule 59 aetiological 59 PTEN protein 59 enzyme kinetics 59 fatty acid biosynthesis 59 5 hydroxymethylcytosine 59 organogenesis 59 phenotypic variability 59 neutralizing antibody responses 59 ERK2 59 nanoscale phenomena 59 deacetylation 59 aptamers derives 59 plasma lipid 59 emotional dysregulation 59 mitochondrial proteins 59 cyclins 59 oxidases 59 microtubule dynamics 59 ARF1 59 photoreceptor cell 59 pharmacodynamic parameters 59 bacterial flagellum 59 Quantum mechanics 59 tumorigenicity 59 E#F# 59 NR2B subunit 59 renal fibrosis 59 somatic motility 59 P. falciparum parasites 59 dysbindin 59 neurotransmitter GABA 59 PI3K AKT 59 K ras mutations 59 S. cerevisiae 59 biomarker identification 59 physico chemical 59 IRE1 59 nonlinear dynamics 59 residual confounding 59 COX enzymes 59 transcriptional machinery 59 artifactual 59 immunodominant 59 membrane permeability 59 nonlinear optical 59 cell adhesion molecules 59 silico prediction 59 NKT cell 59 Cathepsin B 59 gene rearrangements 59 GABAergic 59 mtDNA mutations 59 VEGF expression 59 Foxp3 59 vermis 59 overactivation 59 TP# gene 59 somatostatin 59 bacterial genomes 59 multi celled organisms 59 Eukaryotes 59 eNOS 59 calcium homeostasis 59 BCL#A 59 isotypes 59 phenotypic traits 59 MMP# 59 #T# L1 59 mesoscopic 59 lymphoid cells 59 TMEM#B 59 neurosteroid 59 potentiating 59 proteoglycan 59 electrophysiologic 59 p#NTR 58 IKK2 58 Brain plasticity 58 molecular signaling pathways 58 Phenotypic 58 methodologic 58 ontogeny 58 Mendelian 58 lipoprotein metabolism 58 fatty acid metabolism 58 vitamin D receptors 58 intercellular communication 58 multisensory integration 58 microRNA genes 58 Rigorous scientific 58 Foxp2 58 CNTNAP2 58 xenobiotic 58 NOD mouse 58 causal inference 58 biologic plausibility 58 evolutionarily conserved 58 evolutionarily ancient 58 hyperactivated 58 HER2 positivity 58 messenger ribonucleic acid 58 neuropathologic 58 stochasticity 58 RRM1 58 SCD1 58 progranulin 58 morphogens 58 attentional blink 58 Reproducibility 58 organismal 58 FOXM1 58 organophosphorus compounds 58 GABRA2 58 alpha7 58 habenula 58 isoenzymes 58 filamentous fungus 58 HIF 1α 58 RT qPCR 58 codon usage 58 norepinephrine reuptake inhibition 58 lateralization 58 lymphocyte activation 58 mechanistic studies 58 genotoxic stress 58 quantum superpositions 58 Genetic predisposition 58 ERK signaling 58 neuronal plasticity 58 antitumor efficacy 58 misregulation 58 epigenetic reprogramming 58 ABCB1 gene 58 amino acid substitutions 58 neurochemistry 58 synthetic siRNAs 58 spatio temporal 58 perturbation theory 58 prognostically 58 effector function 58 Vps# 58 agonism 58 glycogen synthesis 58 primary cilia 58 CpG rich 58 amyloidogenic 58 generalisability 58 TMPRSS6 58 sarcosine 58 transcriptional regulators 58 heritable disorders 58 mitogen activated protein kinases 58 Rab5 58 COMMD1 58 physiological mechanisms 58 phenotypes 58 Polycomb proteins 58 antisense RNA 58 pseudogene 58 pharmacokinetic interactions 58 PKC isoforms 58 motor neuron degeneration 58 hormone secretion 58 FSH receptor 58 testable hypothesis 58 cyclic AMP cAMP 58 Treg cell 58 eotaxin 58 unmeasured confounders 58 effector functions 58 chromosomal aberrations 58 EphA2 58 inflammatory cytokine 58 mechanistic insights 58 p# Shc 58 Angiotensin converting enzyme 58 pathogenic mechanisms 58 TRAIL induced apoptosis 58 androgen depletion 58 Abeta# 58 cathepsins 58 #S rRNA gene 58 antibody antigen 58 neuronal function 58 GABAergic neurons 58 granzyme B 58 STAT3 signaling 58 assortative mating 58 biopsychosocial 58 molecular mimicry 58 physiological adaptations 58 Sonic hedgehog 58 hypoperfusion 58 auditory neurons 58 antigenic epitopes 58 neurosensory 58 chromosome condensation 58 astrocytic 58 Sirt1 58 adipokines 58 Htt 58 endogenous ligands 58 SIRT1 protein 58 quantitative trait loci 58 VHL gene 58 chromatin remodeling 58 oncoproteins 58 secretory pathway 58 hypothalamic pituitary adrenal axis 58 histone modification 58 Th2 responses 58 enzyme cofactor 58 proline rich 58 LKB1 58 physicochemical properties 58 HER2 neu 58 Imprinted genes 58 neurotrophic 58 factor receptor FGFR 58 FUS1 58 NKG2D 58 demethylase 58 C. neoformans 58 CDK8 58 Hox gene 58 iPSC 58 ERK1 58 cystic fibrosis transmembrane 58 BDNF gene 58 RQ PCR 58 commensal bacteria 58 amphioxus 58 eIF2 58 vitro assay 58 Hh pathway 58 dependences 58 miR #a [002] 58 spermidine 58 intracellular bacteria 58 costimulation 58 Tasigna prolongs 58 granzyme 58 unicellular organism 58 C1q 58 fascin 58 vascular dysfunction 58 Apolipoprotein E 58 S. sanguinis 58 proteolytic activity 58 CCR7 58 transitivity 58 antiangiogenic activity 58 Neuregulin 1 58 highly pathogenic viruses 58 transcriptomics proteomics 58 SMAD4 58 germline cells 58 receptor subtypes 58 orthologs 58 pathophysiologic 58 gold nanoclusters 58 p# INK4a 58 thymidylate synthase 58 KLF4 58 serine protease 58 prostaglandin synthesis 58 modulatory 58 GLUT1 58 platelet activation 58 apoptosis pathway 58 PPARg 58 atherogenesis 58 glycosyltransferase 58 parameter estimation 58 ZNF# 58 Xenopus embryos 58 gravitational redshift 58 Telomere length 58 enzyme catalysis 58 HOTAIR 58 spatial cognition 58 gliosis 58 Dictyostelium 58 computational geometry 58 FGF signaling 58 NO synthase 58 chromosomal instability 58 ERK phosphorylation 58 #S rRNA 58 immunomodulatory effects 58 left ventricular diastolic 58 NADPH oxidase 58 phenotypic differences 58 biotransformation 57 T lymphocyte 57 α synuclein 57 occludin 57 tumor suppressor PTEN 57 adaptive immunity 57 fusion enhancers 57 VEGFR1 57 bilaterians 57 NMDAR 57 TRPV4 57 Amino acid 57 biochemical assays 57 neuronal signaling 57 indels 57 tRNA synthetases 57 insulin signaling pathway 57 dimeric 57 GFP fusion 57 adrenal hormone 57 signaling cascades 57 mRNA molecules 57 ChIP seq 57 bone marrow mesenchymal stem 57 metabolizing enzymes 57 ginsenosides 57 CD# expression [001] 57 heterogeneous catalysts 57 homodimers 57 alexithymia 57 miRNA molecules 57 trans palmitoleate 57 plexiform neurofibromas 57 oligodendroglial progenitor cells 57 NRF2 gene 57 mda 7 57 noncoding 57 dysbindin gene 57 uncharacterized 57 neuro physiological 57 obligate intracellular 57 hypometabolism 57 CSHL scientists 57 PECAM 1 57 redox active 57 RUNX3 57 baroreceptor reflex 57 sleep deprivation impairs 57 Glutamic acid 57 DNA polymerases 57 Genetic variants 57 amino acid substitution 57 Notch1 57 hypothalamic pituitary 57 assortative 57 #S rRNA genes 57 Mutational 57 photosystem II 57 soluble proteins 57 neuropsychological impairments 57 natriuretic peptides 57 lipid homeostasis 57 hepatoma 57 mTOR signaling pathway 57 nucleolar dominance 57 nicotinic receptor 57 RNA polymerases 57 segmental duplications 57 uPAR 57 introgression 57 heritable traits 57 zebrafish genome 57 autophagic 57 physiologic mechanisms 57 ERK1 2 57 cytochrome oxidase 57 RIP1 57 molecular determinants 57 Wnts 57 Ashwell receptor 57 Anticalins R 57 epigenetic inheritance 57 hexose 57 nonviral gene therapy 57 sea urchin genome 57 cofactors 57 spore formation 57 telomere DNA 57 multiprotein complex 57 Proximate cause 57 replicase 57 proapoptotic 57 fusogen 57 chaperone proteins 57 metazoans 57 TPMT 57 enzymatic reactions 57 Nambu theories permeate 57 intestinal microflora 57 brain neurochemistry 57 electroencephalographic 57 remains mystery Yairi 57 chromatin immunoprecipitation ChIP 57 mirror neuron system 57 Asperger syndrome Rett syndrome 57 GABAergic interneurons 57 Aromatase 57 plexiform 57 indel 57 Kaplan Meier curve 57 circadian rhythmicity 57 CCL5 57 etiological factors 57 MALAT1 57 adipocyte 57 antisense strand 57 guanosine 57 APOBEC3G 57 plausible hypothesis 57 graphene electrons 57 MEK1 57 sRNA 57 hypericin 57 gene deletions 57 UCP2 57 melanocyte 57 chromatin modifications 57 electromechanical coupling 57 Fas ligand 57 Th2 immune 57 meta analytic 57 N Myc 57 experimentally validated 57 Membrane proteins 57 enzymatic activity 57 amyloid deposition 57 catalytic antibodies 57 metacognition 57 DARPP 57 IDH mutations 57 morphologic 57 redox reactions 57 homologous genes 57 amyloid β 57 amyloid plaque formation 57 adipokine 57 ataxias 57 p#/CBP 57 paraneoplastic 57 antiangiogenic 57 mitogen activated protein kinase 57 falsifiability 57 humoral 57 nNOS 57 phylogeographic 57 phonological processing 57 plasma lipoprotein 57 noncognitive 57 antibody mediated 57 myosin VI 57 podocytes 57 certain protein tyrosine 57 amyloid beta plaque 57 stochastic simulation 57 glutamatergic 57 mRNA decay 57 chimp genomes 57 CALHM1 57 Bayesian inference 57 histone deacetylase HDAC 57 Hfq 57 ncRNA 57 IRF5 57 receptor kinase 57 GPIHBP1 57 C#T [002] 57 SHANK3 57 PML RARA 57 c Src 57 scientifically testable 57 genomic alterations 57 Vangl2 57 3'UTR 57 downregulating 57 aneuploid cells 57 apolipoproteins 57 circadian genes 57 Hedgehog signaling 57 synapse formation 57 orally bioavailable mimics 57 spatial reasoning 57 GPx 57 dose proportionality 57 cdk5 57 C EBP alpha 57 neoplastic transformation 57 histone deacetylases 57 HIF 1a 57 dedifferentiation 57 HDAC2 57 nanocomposite material 57 primate genomes 57 hematopoietic cells 57 infectious prion proteins 57 mammalian proteins 57 symbioses 57 cortical excitability 57 gene loci 57 receptor subunits 57 atomistic simulations 57 Rap1 57 noncoding RNAs 57 chromatin modification 57 methyltransferases 57 NF kB pathway 57 titin 57 irreducible complexity 57 schizotypal 57 Pseudomonas syringae 57 HMGCR 57 transcriptionally 57 neuromuscular junction 57 ligand induced 57 glucosides 57 ENMD # 57 hpSCs 57 replicative 57 Myosin II 57 biosynthetic pathways 57 sexually dimorphic 57 cytokine signaling 57 splice variant 57 μ opioid receptor 57 epigenetic markers 57 urocortin 57 miRs 57 SOCS2 57 kinase inhibition 57 tRNA synthetase 57 agonist antagonist 57 CYP#E# 57 phonics fluency vocabulary 57 Multiple logistic regression 57 Transcription factors 57 hermaphroditism 57 cybrid 57 MEF2A 57 H#Y 57 osteogenic differentiation 57 isotype 57 meta cognitive 57 serine threonine 57 Heisenberg principle 57 metabolic enzymes 57 pro angiogenic 57 miR #a [001] 57 genotypic 57 #beta HSD1 57 neuropathological 57 mirror neuron 57 cholesterol homeostasis 57 inbred strains 57 cytoprotective 57 genetic susceptibilities 57 teleost fish 57 TGFb 57 genomic imprinting 57 additively 57 Mendelian genetics 57 TGFβ 57 transmembrane protein 57 circuitries 57 NS4B 57 peripheral insulin sensitivity 57 Wnt beta catenin 57 phosphatases 56 stathmin 56 Gene Ontology 56 behavioral abnormalities 56 HMG CoA reductase 56 nonvascular 56 synovial cells 56 microwell plate 56 globular proteins 56 mitochondrial fusion 56 pseudogap phase 56 B7 H4 56 allosteric 56 GFP fluorescence 56 proteomic analysis 56 cosmological models 56 #β HSD1 56 rifamycins 56 endocannabinoid signaling 56 microarray gene expression 56 endogenous ligand 56 metabolite concentrations 56 multivariate regression analysis 56 clonally 56 PI3K signaling 56 dimensional nanostructures 56 peptoid 56 replicon 56 neo Darwinism 56 nondeterministic 56 diathesis 56 osmotic stress 56 lincRNA 56 Leydig cell 56 focal adhesions 56 tropomyosin 56 maturational 56 anti inflammatory cytokine 56 hemoglobins 56 mathematical notation 56 vectorial 56 analogical reasoning 56 myofibroblast 56 neuroactive 56 lipin 56 CDK9 56 GCN2 56 lymphoid tumors 56 irreducibly complex 56 IFN γ 56 ErbB receptors 56 #S rDNA 56 neutrino oscillation 56 PON1 56 generative grammar 56 endoxifen 56 prostaglandin E2 PGE2 56 TLE3 56 Wnt1 56 transgenesis 56 receptor signaling 56 eicosanoid 56 biological macromolecules 56 BDNF protein 56 oncogenic signaling 56 perilipin 56 RNAi mediated 56 eukaryotic cell 56 neurophysiological 56 ontogenetic 56 biogenesis 56 cardiogenic 56 immunofluorescent 56 somatic mutations 56 thyrotropin 56 epigenetic silencing 56 LPA1 receptor 56 Proteostasis Network 56 Shp2 56 eIF4E 56 Lamarckian 56 estrogen metabolism 56 cardiac fibroblasts 56 microarray datasets 56 multinomial 56 Contagious yawning 56 multigene 56 synthetic peptides 56 Thyroid hormone 56 HDAC enzyme 56 genetic modifiers 56 thermodynamic stability 56 Signal transduction 56 correlational 56 MAPKs 56 PKC delta 56 CXCL5 56 neuroinflammation 56 ubiquitylation 56 hitherto unrecognized 56 prefrontal cortical 56 Stat1 56 mucinous 56 kidney urologic 56 laforin 56 MCH neurons 56 serum lipid 56 coevolution 56 carbonate globules 56 phylogenetic analyzes 56 metabolizing enzyme 56 costimulatory 56 chromosome aberrations 56 homologues 56 cellulases 56 nongenetic factors

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