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(Click for frequent words.) 70 hippocampal neurons 67 pyramidal cells 67 dorsal horn 67 NR2B subunit 67 dendritic spines 67 dentate gyrus 66 glutamatergic 66 interneurons 66 neuronal synapses 66 GABAergic interneurons 65 microglial 65 astrocytic 65 glial 65 hippocampal 65 Purkinje cell 65 cortical neurons 65 excitatory synapses 65 SOCS3 65 ERK signaling 64 cortical 64 glia cells 64 syntaxin 64 AMPA receptors 64 postsynaptic 64 inhibitory interneurons 64 granule cells 64 presynaptic 64 TrkB 64 cAMP signaling 64 immunoreactivity 64 synaptic function 64 Aâ 64 rostral 64 inferior frontal 64 Fig. 1C 64 synaptogenesis 64 perivascular 64 striatal 64 inhibitory synapses 64 vacuolar 63 caveolae 63 myofibroblasts 63 noradrenergic 63 amyloid deposits 63 Rab5 63 Purkinje cells 63 dorsolateral 63 lymphoid cells 63 neurones 63 ganglion cell 63 NR2B 63 cortical regions 63 cingulate 63 Fig. 2b 63 basolateral 63 somatosensory cortex 63 medial frontal cortex 63 TRPV1 receptors 63 tau aggregates 63 mesoderm 63 neurite outgrowth 63 neuroligin 63 PDZ domain 63 ACh 63 intestinal epithelium 63 SVZ 63 fusiform gyrus 63 morphogen 63 microglial activation 63 insulin signaling pathways 63 BMP signaling 63 cardiac fibroblasts 63 hypothalamic 62 F actin 62 CD#b 62 MAP kinase 62 proteoglycan 62 glioblastoma cells 62 cultured neurons 62 hindbrain 62 TGF β 62 fig. S4 62 mesenchyme 62 transmembrane protein 62 neuroligins 62 cathepsin B 62 posterior cingulate 62 transcriptional repressor 62 adhesion molecule 62 Fig. 2B 62 serotonin neurons 62 cell adhesion molecule 62 cortices 62 paxillin 62 subcortical 62 rat hippocampus 62 TGF ß 62 neuronal plasticity 62 transmembrane 62 orbitofrontal cortex OFC 62 Confocal microscopy 62 #ß 62 NMDAR 62 NMDA receptors 62 gyri 62 amyloid β 62 superior temporal gyrus 62 glutamate receptors 62 synapse formation 62 neurofilament 62 gyrus 62 neurone 62 N acetylaspartate 62 cypin 62 serine protease 62 nucleolar 62 neuromuscular junction 62 subventricular zone 62 entorhinal cortex 62 medial prefrontal 62 tau protein 62 Fig. 1D 62 neurons 62 acetylcholine receptor 62 vascular endothelial cells 62 parahippocampal gyrus 62 neuronal 62 neuronal signaling 62 TGF ß1 62 OGG1 62 Fig. 1a 62 Brodmann Area 62 neurosensory 62 retinal neurons 62 chondrocyte 61 beta1 integrin 61 chromosome #q#.# [001] 61 medial temporal lobes 61 oligomerization 61 catenin 61 Brain derived neurotrophic 61 amyloid beta plaques 61 occipital cortex 61 prefrontal cortical 61 cerebellar 61 neurites 61 reticular 61 focal adhesion 61 Ca2 + 61 constitutively active 61 gamma oscillations 61 thalamic 61 extracellular matrix proteins 61 MMP# 61 neuronal stem cells 61 p#NTR 61 Fig. 1A 61 anterior cingulate 61 CXCL# 61 AMPA receptor 61 toxic beta amyloid 61 lipid rafts 61 beta amyloid peptide 61 inhibitory transmitter 61 adrenal cortex 61 β amyloid 61 fig. S# 61 monoamine 61 myelination 61 Fig. 2a 61 inferior parietal 61 FGF2 61 perirhinal cortex 61 epithelia 61 Aβ 61 adipocyte 61 medulla 61 glutamatergic neurons 61 forebrain 61 MDSCs 61 temporoparietal 61 neurotrophin 61 dopamine D1 61 GABAA receptors 61 aggrecan 61 hippocampal formation 61 nAChR 61 epidermal cells 61 acetylcholine receptors 61 calmodulin 61 ERK1 2 61 mammary stem cells 61 Fig. 3b 61 chemoattractant 61 prefrontal regions 61 cytoskeletal 61 serotonin receptor 61 basal ganglia 61 Hippocampal 61 MMP9 61 Nod1 61 glutamate transporters 61 secretory pathway 61 cardiac myocytes 61 sphingolipid 61 ganglion cells 61 neuritic plaques 61 immunoreactive 61 CCR7 61 condensin 61 synaptic vesicles 61 choroid 61 #HT#A 61 Fig. 1c 61 nicotinic receptors 61 multinucleated giant cells 60 dorsolateral prefrontal 60 acetyl CoA 60 intramolecular 60 intraparietal sulcus 60 excitatory 60 cultured rat 60 secretase 60 miR# 60 inflammatory cytokine 60 acyl CoA 60 fig. S1 60 BDNF gene 60 periventricular 60 anterior pituitary 60 MT1 MMP 60 HepG2 cells 60 depolarizing 60 Fig. 4B 60 punctate 60 secretory cells 60 protein tyrosine phosphatase 60 fatty acid oxidation 60 basal forebrain 60 Fig. 3A 60 fibrillin 60 podocytes 60 GLUT4 60 posterior cingulate cortex 60 anterior cortex 60 H#K#me# 60 atherosclerotic lesions 60 phosphorylated tau 60 tetramer 60 phospholipase 60 Aß 60 cyclic AMP cAMP 60 VEGFR1 60 metabolizing enzyme 60 amyloid peptides 60 exocytosis 60 cell adhesion molecules 60 catecholamine 60 afferents 60 synaptic 60 ciliated 60 acetylcholine neurotransmitter 60 HDAC2 60 lysosomal 60 calcium homeostasis 60 ventrolateral 60 γ 60 habenula 60 myocytes 60 HOTAIR 60 serotonergic neurons 60 membrane lipids 60 hypocretin neurons 60 axonal 60 pineal 60 osteoblast 60 mPFC 60 lymphangiogenesis 60 PcG proteins 60 alpha secretase 60 parietal lobes 60 nAChRs 60 Fig. 1E 60 inhibitory neurotransmitters 60 metaplasia 60 myocyte 60 synuclein 60 5 hydroxytryptamine 60 fibrillar 60 coexpression 60 rCBF 60 caveolin 60 globus pallidus 60 CEACAM1 60 ventromedial 60 non coding RNA 60 glutamate signaling 60 rotaxanes 60 excitatory neurotransmitter glutamate 60 amyloid peptide 60 primary cilia 60 colocalization 60 EGFP 60 PC# cells 60 ß amyloid 60 receptor subunit 60 goblet cells 60 globin gene 60 dendritic spine 60 oculomotor 60 motoneurons 60 #HT#A receptor 60 M1 muscarinic 60 cytosol 60 serotonin transporters 60 opioid receptor 60 SUMOylation 60 cortex 60 cdk5 60 fusiform 60 myogenic 60 mitochondrial respiration 60 P cadherin 60 fronto 60 subcellular compartments 60 C1q 60 amyloid beta peptides 60 hypothalamic pituitary 60 CDH# 60 adult neurogenesis 60 zebrafish embryo 60 dopamine signaling 60 lateral hypothalamus 60 tyrosine phosphorylation 60 calpain 60 toxic amyloid beta 60 phosphoinositide 60 afferent 60 leptin signaling 60 JAK STAT 60 focal adhesions 60 5 HT2C receptor 60 dermal papilla 60 GABAA receptor 60 NAc 60 focally 60 intermediate filaments 60 Shh signaling 59 neuroepithelial cells 59 amygdalae 59 neuronal dysfunction 59 neuronal activity 59 autocrine 59 homodimer 59 senile plaques 59 TGF beta1 59 upregulates 59 osteoblastic 59 olfactory sensory neurons 59 hyperintensities 59 S#A# [002] 59 astrocyte 59 H#K# [002] 59 kainate 59 mRNA expression 59 subgenual cingulate 59 CatB 59 vitamin D receptors 59 locus coeruleus 59 PTPN# 59 transcriptional activation 59 dopamine neuron 59 GABAergic neurons 59 endonuclease 59 GABA receptor 59 uPAR 59 microvessels 59 neurofibrillary 59 oligodendroglial progenitor cells 59 Vps# 59 caspase activation 59 intracellular signaling 59 capillary endothelial cells 59 synaptic proteins 59 thermosensitive 59 osteoclast 59 hepatocyte growth 59 hexamers 59 synaptic vesicle 59 CB1 receptors 59 keratinocyte 59 mRNA encoding 59 abnormal neuronal 59 glutamyl 59 P selectin 59 GluR1 59 beta adrenergic receptors 59 melanocyte 59 paraventricular nucleus 59 hippocampi 59 chemokine receptor 59 IL 1beta 59 Figure 1C 59 depolarization 59 GFP fluorescence 59 cortico 59 FKBP# 59 catalase 59 glomerular 59 parietal cortices 59 PBMCs 59 PIP3 59 hypothalamic pituitary adrenal HPA 59 demyelination 59 CagA 59 sGC 59 ependymal cells 59 PON1 59 SIRT1 gene 59 MEK1 59 hyperintensity 59 amyloid deposition 59 pDC 59 PI3K Akt 59 rostral anterior cingulate cortex 59 Abeta# 59 frontotemporal 59 IL6 59 trabeculae 59 mammalian brains 59 glycosyltransferase 59 vasopressin receptors 59 kD 59 Kv#.# 59 Hcrt 59 circadian genes 59 trabecular 59 lesional 59 c Fos 59 ERK pathway 59 actin polymerization 59 dioxygenase 59 Skeletal muscle 59 cortical activation 59 ERK2 59 echogenicity 59 ADAMTS# 59 secretory 59 hyperactivation 59 MMP2 59 HbF 59 IGFBP2 59 SWCNT 59 MAPK pathway 59 CYP#B# 59 p# mutations 59 pro angiogenic 59 polypeptide 59 mitogen activated protein kinase 59 sensory axons 59 neural tissue 59 neuronal pathways 59 raphe 59 lipoxygenase 59 acinar 59 cyclophilin D 59 neovascularization 59 adenylyl cyclase 59 junctional 59 excitatory neurotransmitter 59 ouabain 59 polycystin 59 CA1 59 urocortin 59 dendrite 59 mitochondrial membranes 59 sensory neuron 59 brain derived neurotrophic 59 glutamate receptor 59 phosphoprotein 59 Astrocytes 59 cytosolic 59 serotonin receptors 59 dimers 59 neural cells 59 gamma aminobutyric acid 59 adipose cells 59 dimeric 59 protein kinase C 59 hippocampal cells 59 amygdale 59 midbrain 59 huntingtin 59 Fig. 3B 59 pyruvate kinase 59 neurite 59 SIRT2 58 synaptic transmission 58 POMC neurons 58 Neurogenesis 58 BMP receptor 58 ß1 58 epitaxial layer 58 β catenin 58 #q#.# [002] 58 pulvinar 58 SMAD4 58 neuropeptides 58 constitutively 58 dopamine receptors 58 Ubx 58 glomerulus 58 renal fibrosis 58 BACE1 58 insular cortex 58 cytokine signaling 58 coiled coil 58 Dpp 58 innervation 58 maturational 58 mononuclear 58 estrogen receptor alpha 58 Amyloid beta 58 ß catenin 58 cortexes 58 explants 58 Prox1 58 pRb 58 inhibitory 58 IL 1ß 58 gliosis 58 retinal ganglion cells 58 polyamine 58 Notch signaling pathway 58 amino acid substitutions 58 N cadherin 58 phagocyte 58 TNFR 58 homodimers 58 inferior colliculus 58 Fig. 4b 58 transmural 58 frontal parietal 58 alveolar epithelial cells 58 modulatory 58 fig. S2 58 LDL receptor 58 transcriptional regulators 58 cadherin 58 neurotransmitter GABA 58 branching morphogenesis 58 lymphocyte activation 58 neuritic 58 nitric oxide synthase 58 BRAF protein 58 ENaC 58 proteolytic 58 sensorimotor 58 c Src 58 oscillatory 58 pericytes 58 motor neuron degeneration 58 transmembrane proteins 58 receptor gene 58 intracellular Ca 2 58 transporter proteins 58 Fig. 1d 58 erythrocytes 58 germinal centers 58 picomolar 58 occludin 58 osteogenesis 58 cannabinoid receptors 58 Abeta protein 58 DNMT1 58 temporoparietal junction 58 hydroxylation 58 KLF2 58 transfected cells 58 HUVEC 58 melanopsin 58 glycosylated 58 DARPP 58 Wnt signaling pathway 58 TNFalpha 58 cyclic AMP 58 VEGF receptor 58 extracellular calcium 58 subretinal 58 retinal pigment epithelium 58 microcephalin 58 Notch1 58 plastid 58 myogenesis 58 primary visual cortex 58 BMP4 58 IgG1 58 retinal nerve 58 ChR2 58 gamma aminobutyric acid GABA 58 ventral pallidum 58 TGFβ 58 prefrontal lobe 58 Prefrontal 58 inferior parietal lobule 58 antiapoptotic 58 TSLP 58 factor BDNF 58 semiconductor nanowires 58 striated muscle 58 vascular endothelial 58 interneuron 58 Glial 58 #S proteasome 58 synapses 58 cholecystokinin CCK 58 CaM 58 p# MAPK 58 LTB4 58 neuronal membranes 58 neuron 58 isoenzymes 58 mesolimbic 58 synovial tissue 58 insoluble plaques 58 metaphase 58 mammalian brain 58 ubiquitin ligase 58 5 HT1A 58 mesenchymal cell 58 radial glia 58 piriform cortex 58 Fig. 1b 58 disulfide bond 58 histone acetylation 58 activated macrophages 58 downregulated 58 CB2 receptors 58 intercellular communication 58 activin 58 E3 ligase 58 6S RNA 58 Neuregulin 1 58 neural progenitor cells 58 GAGs 58 ABCA1 58 phosphatidylinositol 58 glia 58 LIS1 58 Fig. 4a 58 multisensory integration 58 lateral orbitofrontal cortex 58 osteocytes 58 dorsal anterior cingulate cortex 58 lateral ventricle 58 brain cortex 58 neuronal circuits 58 porphyrins 58 multinucleated 58 NFTs 58 apical 58 parenchyma 58 FGFs 58 kinesin motor 58 site directed mutagenesis 58 TGF b 58 perinuclear 58 superior colliculus 58 β 58 UCP1 58 TRPV4 58 p#Kip# 58 heterodimers 58 axon guidance 58 synovial cells 58 Cathepsin B 58 arcuate nucleus 58 serine 58 HEK# cells 58 palmitate 58 HDAC6 58 mu opioid 58 somites 58 kinase domain 58 glucose transporter 58 glial cells 58 plexiform 58 brain parenchyma 58 medial frontal 58 E3 ubiquitin ligase 58 granzyme B 58 hexose 58 Th1 cells 58 differential gene expression 58 exonuclease 58 enzymatic activity 58 COOH terminal 58 skeletal muscle cells 58 BrdU 58 dorsal root ganglion 58 guanosine 58 spectrin 58 palytoxin 58 electroencephalographic 58 demyelinated 58 medial temporal 58 Leydig cell 58 alpha subunit 58 transcriptional regulation 58 downregulate 58 myelinated axons 58 parietal 58 Sonic hedgehog 58 microRNA molecules 58 calcium permeable 58 activated microglia 58 anterior cingulate gyrus 58 amyloid beta plaque 58 Histone deacetylase 58 MALAT1 58 neurotransmitter receptors 58 neuronal connections 58 Cx# [001] 58 neurotransmitter glutamate 58 proto oncogene 58 p#/CBP 58 vermis 58 synaptic cleft 58 CaM kinase II 58 Inhibitory 58 efferent 58 prefrontal brain 58 cytochrome 58 ubiquitylation 58 connexin 58 eNOS 58 apoE 58 Dysregulation 58 receptor tyrosine kinase 58 tumorigenicity 58 Fig. 2C 58 deacetylation 58 extracellular 58 Htt 58 alpha synuclein protein 57 TRPV3 57 cellularity 57 ipRGCs 57 KLF4 57 apical membrane 57 medial prefrontal cortex mPFC 57 amygdala neurons 57 EphA2 57 tenascin C 57 olfactory receptor neurons 57 vesicle fusion 57 SNARE proteins 57 ERK1 57 CD1d 57 basal cells 57 synaptic inputs 57 genetic loci 57 Dopaminergic 57 electrical conduction 57 ectoderm 57 autophagic 57 SNAREs 57 epididymal 57 presenilin 57 neuronal cell 57 ERK phosphorylation 57 overactivation 57 Androgen receptor 57 inhomogeneities 57 visual cortex 57 ATPase 57 mutant huntingtin protein 57 ribosomal protein 57 Neural stem cells 57 transgenic mouse models 57 serine threonine 57 Fig. 3a 57 JAK2 enzyme 57 retinoid X 57 neuronal differentiation 57 lamellar 57 thymocyte 57 N acetyl 57 protein tau 57 ER alpha 57 caudate 57 hippocampus 57 dystroglycan 57 intestinal epithelial cells 57 Fig. 3C 57 nonlinear optical 57 substantia nigra 57 5' triphosphate 57 trophoblast cells 57 Amino acid 57 synaptic plasticity 57 BDNF protein 57 cathepsins 57 microelectrode array 57 aggregated Abeta 57 FGF signaling 57 parahippocampal 57 cilium 57 dopaminergic neurons 57 trimeric 57 C3 convertase 57 cyclin E 57 cerebral hemispheres 57 CD# CD# 57 remyelination 57 Amyloid Precursor Protein 57 immunofluorescence microscopy 57 β1 57 transgene expression 57 electrophilic 57 beta amyloid proteins 57 histone methylation 57 serotonergic 57 cingulate gyrus 57 p# mitogen activated 57 tubulin 57 p# activation 57 Akt activation 57 matrix metalloproteinase 57 IFN γ 57 collagenous 57 amyloid beta proteins 57 putamen 57 nicotinic receptor 57 dendritic 57 trigeminal 57 medullary 57 anterior temporal 57 myometrium 57 axonal damage 57 cholesterol homeostasis 57 corticospinal 57 synaptotagmin 57 Wnt signaling 57 hydrated electron 57 proteolytic cleavage 57 centrosome 57 neuronal migration 57 DRG neurons 57 pDCs 57 trophoblasts 57 ectodermal 57 FGFR3 57 monocytes macrophages 57 PU.1 57 focal adhesion kinase FAK 57 histone H3 57 angular gyrus 57 TCF#L# 57 MCF7 cells 57 acetyltransferase 57 PDGFR alpha 57 receptor gamma 57 hsp# 57 lung epithelium 57 forkhead 57 cysteines 57 nicotinic acetylcholine receptors 57 vimentin 57 excitatory neurons 57 TNFa 57 intercellular signaling 57 cytochrome c oxidase 57 5 HT2A 57 fluorescence intensity 57 miR #a [002] 57 monomeric 57 mice genetically altered 57 SCID mice 57 mitral cells 57 inhomogeneity 57 dorsal root 57 mitochondrial enzyme 57 IGF1 57 dysbindin 57 T#M 57 suppressor gene 57 GSTP1 57 muscarinic receptors 57 metabolizing enzymes 57 adrenoceptor 57 NADPH oxidase 57 Rap1 57 Fig. 1B 57 Tubulin 57 D2 receptor 57 osteocalcin 57 neo cortex 57 glucocorticoid receptors 57 mitochondrial proteins 57 adrenergic receptors 57 nitric oxide synthase NOS 57 ectopic expression 57 PKMzeta 57 voxels 57 cerebral cortical 57 TIMP 1 57 neurofibrillary tangles 57 mucin 57 hexamer 57 microvessel 57 thermodynamic stability 57 translationally 57 tumor suppressor protein 57 corticospinal tract 57 bronchial epithelial cells 57 RNA polymerases 57 globular proteins 57 phospholipid membranes 57 CA3 57 neuroendocrine 57 beta amyloid peptides 57 Notch signaling 57 adenylate cyclase 57 Actin filaments 57 redox reactions 57 oligomers 57 meningeal 57 IKKß 57 Foxp3 57 hormone secreting 57 fibrin deposition 57 Sgk1 57 mammillary bodies 57 synapse maturation 57 proteoglycans 57 carboxy terminal 57 TGF beta pathway 57 Thyroid hormone 57 collagen fibrils 57 sebaceous gland 57 progranulin 57 glycolipid 57 spinous 57 transgenic mice expressing 57 InAs 57 podocyte 57 ciliary 57 hyperexcitability 57 sensory cortex 57 genotoxic stress 57 neural plasticity 57 collagen fibers 57 missense mutations 57 stromal 57 diffusible 57 premotor 57 Supplementary Fig 57 prostatic tissue 57 cytokine IL 57 Immunohistochemical analysis 57 MyD# 57 intraventricular 57 ERalpha 57 vesicular 57 rod photoreceptors 57 beta endorphin 57 Fibroblasts 57 Skp2 57 cholinergic 57 relaxivity 57 ErbB2 57 RhoA 57 endocytic 57 antioxidant enzyme 57 evolutionarily conserved 57 EGFR protein 57 monocyte chemoattractant protein 57 ADDL 57 microstructural 57 PDE#A 57 fission yeast 57 avidin 57 transferase 57 IGF1R 57 microdomains 57 CD#c 57 extracellular domain 57 scavenger receptor 57 caveolin 1 57 nociceptive 57 quinone 57 vascular endothelium 57 subthalamic nucleus 57 Neuronal 57 T2 weighted images 57 TRAF6 57 enolase 57 sortilin