Related by context. All words. (Click for frequent words.) 66 c MET 65 biochemical signaling pathways 65 intracellular protein 64 MAP kinases 64 p# mitogen activated 64 cathepsins 64 CDK5 64 NF kB signaling 63 JAK2 enzyme 63 PI3K pathway 63 FGFR2 63 protein kinase C 63 AT1R 63 protein tyrosine kinase 62 myelofibrosis polycythemia vera 62 cyclin dependent kinases 62 Oyster Creek corroded 62 regulating gene expression 62 MAP kinase pathway 62 hyperphosphorylation 62 downstream effectors 62 PI 3K 62 phosphatidylinositol 3 62 Enzastaurin 61 tyrosine kinases 61 Wnt signaling pathway 61 NOTCH1 61 hepatic stellate cells 61 anaphase promoting complex 61 mitogen activated protein kinase 61 Cathepsin B 61 Flt3 61 leukocyte adhesion 61 intracellular signaling pathways 61 synapse formation 61 protein kinases 61 FGFs 61 Smad3 61 MAPK 61 cell signaling pathway 61 beta amyloid peptide 61 lipoprotein metabolism 61 MAPK pathway 61 cell signaling pathways 61 Oncogenic 61 PI3 kinase 61 Caspases 61 aberrant activation 61 Pten 60 histone deacetylase HDAC 60 ERK1 2 60 PI3K AKT 60 Factor VEGF 60 signal transduction pathways 60 LRP5 60 histone deacetylases 60 Raf MEK ERK 60 Kinases 60 cytolytic 60 ERK pathway 60 underlying vasculopathy 60 oncogenesis 60 tumor suppressor protein 60 Src kinase 60 Genetic variations 60 tumorigenesis 60 PPARγ 60 MEK ERK 60 cell adhesion molecules 60 alpha#beta# integrin 60 neuronal differentiation 60 transcriptional regulation 60 cMET 60 autophagic 60 kidney urologic 60 extracellular signal 60 kinase pathway 60 4E BP1 60 NKX#.# 60 E#F# 60 DNA methyltransferases 60 VIPR2 60 TNF alpha cytokine 60 Hedgehog signaling 60 signaling cascades 60 FGFR1 60 CCR1 59 serine proteases 59 myeloproliferative diseases 59 uPAR 59 ABCA1 59 prostaglandin D2 59 cAMP signaling 59 autocrine 59 glycogen synthase kinase 59 pDC 59 tumor angiogenesis 59 coagulation cascade 59 pro inflammatory cytokine 59 c myc gene 59 regulates gene expression 59 virulence determinants 59 receptor gamma 59 Protein Kinase C 59 signaling pathways 59 COX2 59 apoptotic pathway 59 PAR1 59 PI3K Akt 59 histone deacetylation 59 LPA1 59 proto oncogene 59 cyclin dependent kinases CDKs 59 ERK signaling 59 NFAT 59 biologic pathway 59 Rab# 59 histone deacetylase inhibitors 59 JNK pathway 59 SMAD4 59 telomerase inhibitor 59 E3 ubiquitin ligase 59 pRb 59 NF kB pathway 59 myogenesis 59 NF kappa B 59 retinoic acid receptor 59 MMP2 59 γ secretase 59 Tumor necrosis factor 59 enzymatic pathways 59 lysophosphatidic acid LPA 59 mTOR mammalian target 59 protein tyrosine phosphatase 1B 59 Akt signaling 59 GCN2 59 PML RARA 59 STAT3 58 p# MAPK 58 Chemokines 58 primary cilia 58 potently inhibit 58 receptor tyrosine kinase 58 NS4B 58 cyclic AMP cAMP 58 HDACs 58 NFκB 58 IGF IR 58 serine protease 58 oncogenic 58 caveolin 1 58 IAP inhibitor 58 Wnt beta catenin 58 neurotransmission 58 chemokine receptor 58 Skp2 58 downregulation 58 SIRT1 gene 58 lipid metabolism 58 enzyme AMPK 58 C5aR 58 mediating pathological inflammation 58 phosphorylates 58 lipid synthesis 58 Wnt pathway 58 chemokine receptors 58 MTHFR 58 JNK1 58 CRAC channel 58 TGF b 58 p# pathway 58 receptors PPARs 58 NS5b 58 synaptogenesis 58 multiple sclerosis psoriasis 58 Oxidative damage 58 adipokines 58 GSK3B 58 mTOR pathway 58 sphingolipid 58 androgen receptor AR 58 sPLA2 58 dysregulated 58 5 HT2A serotonin 58 mTOR inhibitors 58 p# alpha [001] 58 intracellular signaling 58 CENP E 58 potently inhibited 58 immunoregulatory 58 triggers apoptosis 58 lung cancer NSCLC 58 cellular pathways 58 epigenetic regulation 58 c myb 58 FGFR 58 β catenin 58 signaling molecule 58 Aurora kinases 58 GPC5 58 neuroinflammatory 58 retinoid X 58 pathological hallmarks 58 PI3K signaling pathway 58 chromatin remodeling 58 EGFR pathway 58 activating mutations 58 PDGFR 58 PTP 1B 58 induce apoptosis programmed 58 tau phosphorylation 58 receptor PPAR 57 HER pathway 57 tumor suppressors 57 RANK ligand 57 serine threonine kinase 57 NF kappaB 57 JAK2 57 VE cadherin 57 cholesterol metabolism 57 cyclooxygenase 2 57 proapoptotic 57 eotaxin 57 NF κB 57 cytokines chemokines 57 Epstein Barr Virus EBV 57 NF kappaB pathway 57 potent inducer 57 renal fibrosis 57 TNF α 57 transcriptional activation 57 neurofibromin 57 interleukins 57 p# activation 57 pathophysiological effects 57 mesenchymal cell 57 matrix metalloproteinases MMPs 57 neuroligins 57 ERBB4 57 intercellular signaling 57 mTOR signaling pathway 57 Hedgehog signaling pathway 57 hypoxia inducible factor 57 HER signaling pathway 57 glucocorticoid receptors 57 dysregulation 57 activin 57 Vascular Endothelial Growth 57 HDAC2 57 synaptic transmission 57 IL#R 57 ORMDL3 57 hedgehog pathway 57 acetylcholine receptor 57 cardiometabolic disorders 57 serine threonine 57 anti inflammatory cytokine 57 histone deacetylase 57 Misfolded proteins 57 selectively inhibited 57 Stat5 57 BCL2 57 FasL 57 superoxide dismutase 57 basophils 57 beta secretase inhibitors 57 BRAF kinase 57 #beta HSD1 57 neurite outgrowth 57 metabolic enzymes 57 IL #p# 57 Oxidative stress 57 PECAM 57 E3 ligase 57 vimentin 57 CB2 receptor 57 molecule interleukin 57 Akt3 57 Dysregulation 57 GATA3 57 CYT# potent vascular disrupting 57 phosphatases 57 proliferative diseases 57 lysosomal 57 genotoxic stress 57 cytoprotective 57 PDGF receptors 57 ubiquitin ligases 57 prostaglandin synthesis 57 DISC1 57 Fas ligand 57 osteogenic differentiation 57 anticancer therapeutics 57 protein tyrosine phosphatases 57 Glucocorticoids 57 c myc 57 PI3K 57 LKB1 57 tissue fibrosis 57 lymphangiogenesis 57 adhesion molecule 57 Notch pathway 57 ß catenin 57 Aurora kinase 57 MLL2 57 peroxisome proliferator activated 57 methyl D aspartate 57 Akt activation 57 Dendritic cells DCs 57 GSK3 56 RAF kinase VEGFR 56 HER1 56 receptor tyrosine kinase inhibitor 56 cytoskeletal 56 PI3 K 56 TNFalpha 56 PPARg 56 VEGF protein 56 RUNX3 56 secretory phospholipase A2 56 Cdc7 56 CYP #A# 56 leukotriene pathway 56 immune modulator 56 TH# cells 56 lung fibrosis 56 cardio metabolic diseases 56 apoE 56 Hedgehog pathway 56 VEGF receptor 56 selectively inhibit 56 endogenous ligands 56 chromosomal rearrangement 56 effector function 56 upregulation 56 cell adhesion molecule 56 factor receptor FGFR 56 LDL receptor 56 tumor vasculature 56 carbohydrate metabolism 56 cellular signaling pathways 56 pleiotropic 56 focal adhesion kinase FAK 56 GABAA receptors 56 receptor tyrosine kinases 56 Notch1 56 mTOR signaling 56 stem cell pluripotency 56 gastric carcinogenesis 56 cyclin dependent kinase inhibitor 56 biologic pathways 56 NKG2D 56 excess TNF alpha 56 transmembrane receptor 56 PKC isoforms 56 phosphoinositide 3 56 TGF ß 56 signal transduction 56 autoreactive T cells 56 pathogenic mechanisms 56 intracellular pathways 56 cholesterol homeostasis 56 K ras mutations 56 non coding RNA 56 mGluR2 NAM 56 Angiotensin converting enzyme 56 lymphotoxin 56 EGFR tyrosine kinase inhibitors 56 Clusterin 56 PPAR alpha 56 poly ADP ribose polymerase 56 LRP1 56 GRNOPC1 contains 56 JAK kinases 56 paxillin 56 tyrosine phosphorylation 56 Epothilones 56 apoptosis pathways 56 fibrogenesis 56 CTGF 56 potent inhibitors 56 thyroid hormone receptor 56 SOD1 56 Fibroblast 56 potent activator 56 IGF 1R 56 osteoblast 56 ARF1 56 tumor suppressor gene 56 hypothalamic pituitary adrenal axis 56 inhibit oxidative stress 56 intracellular proteins 56 FLT3 56 pro angiogenic 56 myeloproliferative disorders 56 Raf kinase 56 calcineurin 56 Integrins 56 epigenetic alterations 56 receptor alpha 56 oncology metabolic disorders 56 NFkappaB 56 cell motility 56 Systemic lupus erythematosus SLE 56 JAK3 56 PTPN# 56 cytokine signaling 56 Short telomeres 56 PHD2 56 FGFR3 56 actin cytoskeleton 56 mediated inhibition 56 LRP6 56 glial tumors 56 GNAQ 56 glucokinase 56 pathological hallmark 56 molecular pathway 56 Aβ 56 lectin pathway 56 SCD1 56 pancreatic islet beta 56 Factor Receptor 56 TGF beta 56 myopathies 56 abnormal p# 56 Genetic variants 56 glial derived neurotrophic 56 Wnt signaling 56 beta globin gene 56 mGluRs 56 cellular senescence 56 osteoprotegerin 56 osteoclast activity 56 podocyte 56 casein kinase 56 pro apoptotic 56 ectopic expression 56 thromboxane A2 56 DNA hypermethylation 56 anti apoptotic 56 mitotic catastrophe 56 hormone angiotensin II 56 intercellular communication 56 microtubule dynamics 56 protein CETP 56 transient receptor 55 STK# [002] 55 antineoplastic 55 micro RNAs 55 IL 1β 55 cell adhesion 55 epigenetic mechanisms 55 monocytes macrophages 55 Epidermal Growth Factor Receptor 55 protein kinase 55 adipogenic 55 CD#L 55 MAP kinase 55 neurotransmitter glutamate 55 autoreactive B 55 galectin 55 PPAR γ 55 MCSP respectively 55 CaM kinase II 55 papillary renal cell carcinoma 55 small molecule modulators 55 signaling pathway 55 immune modulating 55 demyelinating disease 55 signal transduction inhibitors 55 fibrotic disease 55 Ets2 55 mutational status 55 RAS RAF MEK ERK 55 MEK inhibitors 55 TRAIL induced apoptosis 55 oxidases 55 potent cytotoxic 55 apoptotic cell 55 NOD2 55 IKK2 55 Amyloid beta protein 55 selective inhibition 55 Notch signaling 55 EGFR HER2 55 secreted protein 55 ALK inhibitors 55 caspases 55 basolateral 55 neuronal degeneration 55 cystic fibrosis transmembrane conductance 55 sphingosine 1 55 RAS RAF MEK 55 matrix metalloproteinases 55 effector functions 55 apoptosis proteins 55 monocyte chemoattractant protein 55 costimulation 55 induce apoptosis 55 BCR ABL 55 post transcriptional 55 CK2 55 polyamine 55 deacetylation 55 Th1 cells 55 phosphate S1P 55 neuronal dysfunction 55 Macrophage 55 small molecule agonists 55 spermidine 55 COX enzymes 55 Receptors GPCRs 55 CDK inhibitor 55 thymidylate synthase 55 bioactive lipid 55 mda 7 55 muscle contractility 55 upregulating 55 glucocerebroside primarily 55 lipid metabolites 55 Rho proteins 55 activate SIRT1 55 erlotinib Tarceva 55 overactivation 55 protein alpha synuclein 55 Phosphorylation 55 glycolipids 55 cytokine receptor 55 allergic inflammation 55 PKM2 55 neurotrophic 55 antibody mediated 55 Tß4 55 metalloproteinase 55 sphingolipids 55 RhoA 55 tumor microenvironment 55 Janus kinase 55 mesenchymal transition 55 histone acetylation 55 potent inhibitor 55 AKT pathway 55 tumor metastasis 55 modulates Akt 55 nitric oxide synthase 55 abnormal angiogenesis 55 transthyretin 55 Six3 55 Protease inhibitors 55 neuronal nicotinic receptors NNRs 55 glutamate receptors 55 Smac mimetics 55 XBP1 55 beta arrestin 55 LymphoStat B belimumab 55 prostate carcinogenesis 55 PDGFR B 55 gastro intestinal inflammation 55 alpha folate receptor 55 motor neuron degeneration 55 fatty acid oxidation 55 steroidogenic 55 regulate gene expression 55 metabotropic glutamate receptors 55 Chronic inflammation 55 orally administered inhibitor 55 dihydrofolate reductase 55 amyloidogenic 55 FOXP3 55 SGK1 55 inhibit angiogenesis 55 ubiquitylation 55 RNAi therapeutic targeting 55 kinase PI3K Akt pathway 55 CEA CD# Her2 55 adipocyte 55 neuromuscular junction 55 costimulatory 55 Ras pathway 55 tumor suppressor genes 55 STAT3 signaling 55 GGTase 55 Polycomb proteins 55 neuroendocrine cancers 55 ARID1A 55 Galectins 55 p#Kip# 55 nicotinic acetylcholine receptors 55 polycythemia vera PV 55 TSP1 55 atherogenesis 55 effector cells 55 pDCs 55 EphA2 55 5 HT2A inverse 55 aldose reductase 55 Ribavirin causes 55 coronary vasodilation 55 hedgehog signaling 54 PICALM 54 vascular inflammation 54 Hypoxia Inducible Factor 54 p# MAP kinase 54 ABCB1 54 missense mutations 54 metabolism viral replication 54 misregulation 54 oncogenic signaling 54 BRAF gene 54 vWF 54 PAK1 54 c MYC 54 Tumor Necrosis Factor 54 V#F mutation 54 delta isoform 54 Fibroblast Growth Factor Receptor 54 LPA1 receptor 54 neuropsychiatric diseases 54 Bcr Abl 54 apoptosis programmed cell 54 type glutamate receptor 54 cypin 54 hypermethylated 54 PKC beta 54 cardio renal 54 multiprotein complex 54 novel VDA molecule 54 cyclic adenosine monophosphate cAMP 54 Treg cell 54 tumor suppressor PTEN 54 certain protein tyrosine 54 peroxisomal 54 dimerization 54 eNOS 54 iNOS 54 psoriasis rheumatoid arthritis 54 inactivating mutations 54 histone demethylase 54 selective antagonists 54 NFkB 54 PARP inhibition 54 mitogen 54 proteolysis 54 amyloid cascade 54 PKC enzyme 54 ThermoDox ® clinical 54 RANK Ligand 54 antiapoptotic 54 HCV replication 54 neuronal apoptosis 54 CYP# [002] 54 targeting PCSK9 54 pancreatic carcinogenesis 54 interferon pathway 54 PLA2 54 chitinase 54 muscarinic receptors 54 stellate cells 54 neoplastic transformation 54 underlying pathophysiology 54 EGFR signaling pathway 54 oxidative phosphorylation 54 inflammasome 54 intestinal epithelium 54 SETDB1 54 suppresses tumor 54 keratinocyte 54 triggers apoptosis programmed 54 SCN5A 54 beta secretase 54 A3 adenosine receptor 54 uPA 54 PI3K signaling 54 plasminogen 54 signal transduction pathway 54 telomere dysfunction 54 alpha glucans 54 fast skeletal troponin 54 dopaminergic 54 GLI1 54 ubiquitination 54 factor HGF 54 Src 54 HIF 1alpha 54 NF KB 54 VEGFR 54 neuroinflammation 54 VEGF inhibitors 54 adipogenesis 54 treat musculoskeletal metabolic 54 activated microglia 54 secretory pathway 54 vascular disrupting agents 54 IFN γ 54 KRAS oncogene 54 orally bioavailable mimics 54 endosomal release 54 intracellular pathogens 54 protein p# 54 lipid biosynthesis 54 ligases 54 MT1 MMP 54 estrogen receptor alpha 54 mTORC1 54 mTOR kinase 54 ADAM# 54 tumor suppressor proteins 54 small molecule activators 54 histone deacetylase HDAC inhibitors 54 BMP signaling 54 psoriatic plaques 54 CREB protein 54 microglial activation 54 excitatory neurotransmitter 54 Triapine R potent 54 TGF β 54 HCV polymerase 54 triterpenoids 54 TLR3 54 fatty acid biosynthesis 54 Additionally Nexavar 54 EGF receptor 54 proliferation apoptosis 54 Amyloid plaques 54 gene loci 54 STIM1 54 MAPKs 54 inhibiting tumor 54 glucagon receptor 54 GLUT1 54 induced apoptosis 54 gastrointestinal stromal tumors GISTs 54 immunomodulatory effects 54 adhesion proteins 54 histone deacetylases HDAC 54 amyloid beta plaques 54 RAS pathway 54 ErbB3 HER3 54 SIRT3 54 HDAC inhibition 54 Akt 54 dopamine transporter DAT 54 Cytotoxic T 54 TTR gene 54 glucocorticoid receptor 54 G Protein Coupled 54 essential thrombocythemia 54 Cyclin D1 54 Alzheimer disease pathogenesis 54 messenger molecule 54 TLR8 54 amyloid formation 54 ErbB3 54 GPI anchored 54 induces apoptosis 54 tRNA synthetases 54 Improper braking 54 RKIP 54 alpha TNF alpha 54 LXRs 54 cyclin dependent kinase 54 LHRH receptor positive 54 systemic autoimmune 54 SIRT1 enzyme 54 protein tau 54 NF kB 54 airway remodeling 54 etiologic factors 54 cellular metabolism 54 Darapladib 54 TGF beta pathway 54 immune dysregulation 53 transcriptional repressor 53 peroxisome 53 Aß 53 mGluR4 53 TMEM#B 53 alpha glucosidase 53 protein misfolding 53 MTP inhibitor 53 tumor necrosis 53 drug metabolizing enzymes 53 DGAT1 53 PKC alpha 53 gene rearrangements 53 cyclin E 53 Sp1 53 fusion enhancers 53 nAChRs 53 Th2 cells 53 kinases 53 granzyme B 53 antisense oligonucleotides 53 inflammatory cytokine 53 5 HT6 receptor 53 endoplasmic reticulum stress 53 receptor mediated endocytosis 53 NR2B subunit 53 neuronal signaling 53 Th# cells 53 cholecystokinin CCK 53 molecular pathways 53 specific chemokine receptors 53 FOXO1a 53 secreted proteins 53 AAG geldanamycin analog 53 plasma kallikrein 53 pancreatic colon 53 biochemical pathway 53 hypermethylation 53 autoimmune diseases inflammation 53 amyloid ß 53 Mcl 1 53 childhood leukemias 53 M2 subunit 53 beta catenin 53 molecular signaling pathway 53 sortilin 53 adenosine receptor 53 Y2 receptor 53 colon carcinogenesis 53 thymidylate synthase TS 53 mGluR2 53 proteosome 53 somatic mutations 53 sGC 53 microRNA molecules 53 siRNA therapeutic 53 acetylcholinesterase AChE 53 rheumatoid arthritis multiple sclerosis 53 mitochondrial function 53 AtuPLEX 53 5 lipoxygenase 53 biochemical pathways 53 TNFα 53 redox active 53 Platelet Derived Growth 53 Transcription factors 53 specific lectin receptors 53 catenin 53 Pim kinases 53 neuropsychiatric disorders 53 neurodegenerative diseases 53 Vidofludimus 53 BCL#A 53 MAbs targeting 53 inducible nitric oxide synthase 53 anionic backbone 53 chemokines 53 alpha 2A adrenergic 53 factor PlGF 53 virulence genes 53 beta1 integrin 53 chromatin structure 53 miR #a [002] 53 colorectal carcinogenesis 53 neurotrophic factors 53 Epstein Barr virus EBV 53 oncoprotein 53 carbohydrate polymer 53 NS5B 53 TGF beta1 53 neurofibrillary tangles 53 dephosphorylation 53 estrogen receptor beta 53 Lymphocytes 53 SOD1 gene 53 Eg5 53 molecular biomarkers 53 Overexpression 53 PDE4 53 novel therapeutic antibodies 53 5 HT4 53 RAS MAPK pathway 53 mitogenic 53 upregulates 53 receptor subtypes 53 chemokine 53 amyloid β 53 ryanodine receptor 53 alpha#beta# 53 heme oxygenase 53 MKC# MT 53 engineered RAP peptides 53 inflammatory cytokines 53 obesity insulin resistance 53 Alzheimer disease cognitive impairment 53 noncoding RNAs 53 anterior pituitary 53 5 HT1A receptor 53 neuronal plasticity 53 mTOR 53 E2F 53 constitutive activation 53 PI3K/Akt pathway 53 dendritic spine 53 beta catenin protein 53 commonly mutated genes 53 pyrimidines 53 Treg cells 53 mediated apoptosis 53 gluconeogenesis 53 tau protein 53 S6K 53 Hh pathway 53 super oxide dismutase 53 malignant transformation 53 biased ligand 53 intestinal epithelial cells 53 small molecule inhibitor 53 calcium homeostasis 53 pro inflammatory cytokines 53 tramiprosate Alzhemed TM 53 immuno modulatory 53 paracrine 53 caspase activation 53 neuro degenerative disorders 53 B lymphocyte stimulator 53 selective inhibitors 53 nNOS 53 lymphocyte activation 53 PLX MS 53 p# Shc 53 related apoptosis inducing 53 membrane receptors 53 lipogenesis 53 diagnostic biomarkers 53 PTEN mutations 53 included Raf kinase 53 axonal degeneration 53 fatty acid amide hydrolase 53 mitogen activated protein kinases 53 frataxin 53 anti amnesic 53 rheumatoid arthritis gout 53 Syk 53 Upregulation 53 receptor mediated 53 Symadex 53 p#INK#a 53 TNF blocker therapy 53 carcinogenesis 53 FOXO3a 53 monogenic 53 syngeneic 53 c Myb 53 beta adrenergic receptors 53 SCN9A 53 granulosa cell 53 Angiotensin II 53 small molecule tyrosine 53 protein biosynthesis 53 epigenetic therapies 53 PI3K/Akt pathway inhibitor 53 TNFR 53 chemoresistance 53 antisense inhibitors 53 tumor antigen 53 thyrotropin 53 Th1 type 53 microglial cells 53 cyclooxygenase COX 53 ATC ovarian cancer 53 vivo pharmacology 53 PI3K/mTOR 53 clinically validated targets 53 splice variants 53 PDGF receptor 53 inhibiting enzymes 52 tumorigenicity 52 beta defensins 52 peptide hormone 52 ENMD # 52 D aspartate NMDA receptor 52 GABAA receptor 52 OPHN1 52 TGF alpha 52 Inflammatory bowel diseases 52 leukotrienes 52 beta adrenergic 52 ErbB2 52 genetic polymorphisms 52 Src kinases 52 melanocyte 52 Epidermal Growth Factor 52 lymphomas leukemias 52 humanized monoclonal antibodies 52 humoral immunity 52 EP1 receptor 52 oral ghrelin agonist 52 nAChR 52 demonstrated anti amnesic 52 TNF antagonist 52 UCP2 52 IL 1beta 52 5 HT4 receptor 52 EphB2 52 ALS #-#